Page last updated: 2024-08-17

lysine and Disease Exacerbation

lysine has been researched along with Disease Exacerbation in 108 studies

Research

Studies (108)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (5.56)	18.2507
2000's	19 (17.59)	29.6817
2010's	59 (54.63)	24.3611
2020's	24 (22.22)	2.80

Authors

Authors	Studies
Feng, T; Gu, R; Guo, Y; Li, K; Li, Q; Li, S; Lin, P; Ou, D; Yuan, H; Zhang, J; Zhao, G	1
Ji, T; Liu, A; Mao, X; Weng, Y	1
Bakht, MK; Beltran, H; Cheon, GJ; Dong, X; Fifield, BA; Grimm, J; Hayward, JJ; Kang, KW; Ku, SY; Mader, L; Meister, D; Pillon, A; Porter, LA; Shahbazi-Raz, F; Skubal, M; Stover, M; Stringer, KF; Tamura, R; Trant, JF; Tronchin, A; Venkadakrishnan, VB; Wang, Y; Xue, H	1
Chi, H; Ding, Y; Shao, J; Shi, T; Wang, X; Yu, H	1
Feng, D; Gao, J; Gao, T; Hou, Y; Huang, W; Leng, S; Liu, R; Liu, W; Qiu, R; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zhang, K; Zhang, X; Zheng, Y	1
Chen, W; Du, W; He, Y; Liu, N; Liu, X; Yang, Y; Zhang, Y	1
Bracken, B; Kasper, S; Wong, RM; Wu, T	1
Chen, Y; Gui, X; Jia, S; Jiang, X; Li, J; Li, T; Li, X; Lu, D; Lu, Y; Meng, Q; Pu, H; Song, S; Wang, C; Wang, L; Xie, S; Xin, X; Xu, J; Yang, Y	1
Chu, JW; Im, H; Kim, H; Lee, JM; Park, IG; Park, SC; Song, H	1
Bao, S; Chen, L; Cui, J; Guo, S; Han, Q; He, K; Huang, H; Li, A; Li, D; Li, T; Li, Y; Man, J; Mi, L; Ran, H; Rich, JN; Wang, X; Wu, J; Xiao, D; Yan, X; Yu, Y; Zhan, X; Zhang, S; Zhang, X; Zhou, T	1
Chai, P; Fan, J; Fan, X; Ge, S; Jia, R; Ni, H; Wang, S; Wang, Y; Xing, Y; Yu, J	1
An, T; Li, Y; Ma, P; Mao, B; Ren, B; Sun, B; Wang, H; Zhang, L; Zhou, X; Zhu, L	1
John, R; Konvalinka, A; Pei, Y; Scholey, JW; Song, X; Williams, VR; Zhou, X	1
Cho, SY; Jadvar, H; Kim, CK; Potvin, K; Winquist, E; Zukotynski, KA	1
Cai, Y; Chen, L; Chen, Y; Chen, Z; Feng, Y; Fu, Y; Huang, H; Huang, Y; Liu, R; Zhang, Y	1
Li, X; Mao, L; Zhang, J; Zhang, Y	1
Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F	1
Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W	1
Chen, S; Cheng, X; Fang, W; Hao, H; Hu, X; Hua, F; Huang, D; Huang, Z; Li, Q; Liu, F; Luo, Z; Xiao, F; Zhang, X	1
Fujii, T; Hamamoto, R; Honjoh, H; Inoue, F; Kaneko, S; Kashiyama, T; Kojima, M; Komatsu, M; Kukita, A; Miyamoto, Y; Mori-Uchino, M; Osuga, Y; Sone, K; Taguchi, A; Takahashi, Y; Tanikawa, M; Tsuruga, T; Wada, M; Wada-Hiraike, O	1
Chen, S; Dai, X; Gong, Y; Huang, H; Li, H; Zhao, Y	1
Chen, R; Hou, G; Huang, C; Jiang, B; Li, L; Liu, X; Lu, R; Wang, Y; Yang, Q; Yu, J; Zhao, X	1
Chen, L; da Silva, SR; Gao, SJ; Ju, E; Li, T; Wang, X; Wei, S; Zhang, X	1
Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z	1
Cui, J; Han, J; Ou, J; Qin, Y; Wang, RF; Zhang, C; Zhang, J; Zhi, F	1
Chen, S; Chen, X; Greenblatt, S; Guo, Y; Guo, Z; He, F; Li, J; Li, Z; Man, N; Morey, L; Nimer, SD; Shi, H; Sun, Y; Wang, L; Wang, QF; Wang, QT; Williams, S; Xu, M; Yang, FC; Yang, H; Yu, P; Zhang, P; Zhou, Y	1
Chen, R; Deng, R; Hou, G; Jiang, B; Wang, Y; Xu, M; Yu, J; Yuan, H; Zhang, H; Zhao, X	1
Chen, R; Cui, N; Deng, R; Dou, J; Huang, J; Liu, T; Wang, J; Wang, Y; Yu, J; Zhang, H; Zhao, X	1
Bao, Z; Dai, Z; Jing, L; Li, L; Shao, C; Sun, Z; Wang, Z; Xu, S; Yan, J; Ye, F; Zhu, J	1
Blasetti Fantauzzi, C; Cappello, P; de Latouliere, L; Iacobini, C; Ionta, V; Manni, I; Menini, S; Novelli, F; Pesce, C; Piaggio, G; Pugliese, G	1
Song, J; Wan, J; Wang, P; Wang, T; Wang, Y; Xu, W; Zhan, J; Zhang, H	1
Han, L; Lin, Y; Ma, D; Ma, X; Qin, Z; Qiu, Y; Sun, C; Sun, Y; You, Y; Zhao, Y; Zhu, L	1
Barozzino, M; Castellano, G; Conserva, F; Divella, C; Fiore, MG; Gallone, A; Gesualdo, L; Giorgino, F; Laviola, L; Oranger, A; Papale, M; Piscitelli, D; Pontrelli, P; Rossi, R; Simone, S	1
Anthony, DC; Claridge, TDW; Jagielowicz, M; Probert, F; Simmons, A; Travis, S; Walsh, A; Yeo, T	1
Chen, L; Cheng, H; Li, W; Liu, C; Liu, Y; Zhang, B; Zhang, M	1
Hirata, K; Kitamoto, T; Nakamura, T; Satoh, K; Suzuki, K; Takayanagi, M	1
Nakaya, I; Nakayama, K; Nakayama, M; Soma, J; Tezuka, Y; Yahata, M	1
Liu, H; Ming, L; Wan, J	1
Fülöp, T; Haddad, M; Landri, S; Lepage, A; Perrotte, M; Ramassamy, C	1
Bonini, M; Brien, JO; Dean, AE; Gao, Y; Gius, D; Hart, R; Horikoshi, N; Jiang, H; Kieffer, MB; Liu, G; Park, SH; Quan, S; Satchell, KJF; Stauffer, ME; Tran, EL; Zhu, Y; Zou, X	1
Fang, W; Song, J; Sun, X; Zhan, J; Zhang, H; Zhang, J	1
Damen, J; deGroot, J; Huisman, AM; Lafeber, FP; Mastbergen, SC; Oostveen, JC; Reijman, M; Vos, PA; Welsing, PM	1
Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM	1
Akune, T; Enyo, Y; Hashizume, H; Ishimoto, Y; Kagotani, R; Kawaguchi, H; Muraki, S; Nagata, K; Nakamura, K; Oka, H; Tanaka, S; Teraguchi, M; Toyama, Y; Yamada, H; Yoshida, M; Yoshimura, N	1
Kang, C; Kim, MY; Lee, J; Song, JJ	1
Chen, Z; Li, Z; Lu, S; Niu, X; Shen, S; Tang, N; Xu, L; Xu, Y; Ye, X	1
Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y	1
Chen, CK; Chen, MW; Hsiao, M; Hua, KT; Jan, YH; Jeng, YM; Ko, CH; Kuo, ML; Sung, PL; Wang, MY; Wei, LH; Yen, ML	1
Cui, W; Kong, L; Li, X; Luo, M; Miao, L; Tan, Y; Wu, H; Xu, F; Zhou, S	1
Borghi, R; Cammarata, S; Monacelli, F; Nencioni, A; Odetti, P; Piccini, A; Tabaton, M	1
Fukami, K; Matsui, T; Yamagishi, S	1
Borg, DJ; Forbes, JM; Groop, PH; Härkönen, T; Ilonen, J; Knip, M; Ryhänen, SJ; Salonen, KM; Simell, O; Veijola, R	1
Siddula, A; Sroga, GE; Vashishth, D	1
Culmes, M; Eckstein, HH; Gebhard, H; Greißel, A; Napieralski, R; Pelisek, J; Schmitt, M; Wagner, E; Zernecke, A; Zimmermann, A	1
Brismar, K; Kärvestedt, L; Malmstedt, J; Swedenborg, J	1
Cleary, PA; Gao, X; Genuth, S; Lachin, JM; Monnier, VM; Sell, DR; Sun, W	1
Dekker, JM; Ferreira, I; Gaens, KH; Nijpels, G; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; van de Waarenburg, MP; van der Kallen, CJ; van Greevenbroek, MM	1
Borsos, AM; M'bemba, J; Peyroux, J; Selam, JL; Slama, G; Sternberg, M; Urios, P	1
Ikeda, T; Ito, N; Kurita, H; Maruyama, K; Shimada, A; Shiokawa, Y; Utagawa, A	1
Gaspar, L; Khanna, V; Kruzliak, P; Mishra, N; Prasad, S; Ruia, S; Saxena, S; Singh, V; Staffa, R	1
Fujiwara, N; Imoto, S; Inazawa, J; Kawano, T; Kozaki, KI; Miyano, S; Morishita, M; Muramatsu, T; Tsuda, H; Yamaguchi, R	1
Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L	1
Byun, S; Chiang, CM; Kemper, B; Kemper, JK; Kim, DH; Kwon, S; Park, S; Wu, SY; Xiao, Z	1
Deb, M; Kar, S; Parbin, S; Patra, SK; Pradhan, N; Rath, SK; Sengupta, D	1
Hyötyläinen, T; Kurko, J; Lietzen, N; Mattila, I; Mykkänen, J; Näntö-Salonen, K; Niinikoski, H; Nygren, H; Olkku, A; Orešič, M; Pöhö, P; Simell, O; Tanner, L; Tringham, M; Vähä-Mäkilä, M	1
Chan, CH; Frohman, MA; Lee, HJ; Li, CF; Powers, S; Ruan, D; Thompson, PA	1
Bhatia, A; Chen, M; Dong, H; Guo, J; Hou, Y; Jayaprakash, P; Li, W; O'Brien, K; Sahu, D; Schmidt, T; Situ, AJ; Tong, C; Tsen, F; Ulmer, TS; Woodley, DT; Ying, Q; Zou, M	1
Cui, J; Ou, J; Xia, X; Yang, Z; Zhang, J; Zhi, F	1
Chen, D; Li, L; Li, Y; Su, X; Wang, N; Yin, H	1
Iida, H; Kobayashi, F; Miwa, M; Nagasaka, K; Nagasaka, T; Nakamura, Y; Shindo, K; Shiozawa, Z; Togashi, S; Watanabe, H	1
Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J	1
Al-Zawahary, WM; Mansour, DE; Radwan, AA; Salman, AG; Swelem, AH	1
Hennessy, M; Mayne, PD; McCarthy, P; Murphy, S; Saidha, S	1
Barranco, P; Bobolea, I; Larco, JI; López-Serrano, MC; Prior, N; Quirce, S	1
Buccheri, S; Caccamo, N; Cicero, G; D'Asaro, M; Dieli, F; Eberl, M; Guggino, G; Hayday, AC; La Mendola, C; Meraviglia, S; Orlando, V; Roberts, A; Scarpa, F; Stassi, G; Todaro, M; Vermijlen, D	1
Lee, WY; Wei, YH; Wu, SB; Wu, YT	1
Chang, CC; Chen, ST; Hsieh, TH; Kuo, MY; Li, YJ; Lin, BR	1
Bonner, A; Chen, JM; Cong, X; Czerwieniec, GA; DeGiacomo, F; Ellerby, LM; Gibson, BW; Held, JM; Schilling, B	1
Gomez-Esteban, JC; Lezcano, E; Molano, A; Somme, JH; Tijero, B; Zarranz, JJ	1
Arai, M; Araki, T; Itokawa, M; Kasai, K; Koike, S; Miyashita, M; Miyata, T; Nishida, A; Oshima, N; Takizawa, R	1
An, Y; Chen, D; Jiang, Y; Liu, N; Ren, L; Wang, Z; Zhu, Y	1
Akasaka, J; Kobayashi, H; Koike, N; Naruse, K; Noguchi, T; Oi, H; Sado, T; Tsunemi, T; Yoshida, S	1
D'Amato, E; Di Rocco, M; Famà, A; Garibotto, G; Gianiorio, F; Simonato, A; Verzola, D; Villaggio, B	1
Dillmann, U; Erdmann, P; Papanagiotou, P; Shamdeen, MG; Sühs, KW	1
Avery, NC; De Croos, JN; Grynpas, MD; Kandel, R; Willett, TL	1
Barber, MF; Chen, K; Chua, KF; Garcia, BA; Gozani, O; Kioi, M; Li, W; Michishita-Kioi, E; Moqtaderi, Z; Paredes, S; Struhl, K; Tasselli, L; Tennen, RI; Xi, Y; Young, NL	1
Chen, S; Liu, Y; Sun, FL; Wang, DL; Zhao, L	1
Douvlis, Z	1
Braun, M; Forejtová, S; Gatterová, J; Hulejová, M; Olejárová, M; Pavelka, K; Pavelková, A; Senolt, L; Spacek, P; Stovícková, J	1
Eriksson, J; Hämäläinen, H; Ilanne-Parikka, P; Keinänen-Kiukaanniemi, S; Laakso, M; Laukkanen, O; Lindström, J; Pihlajamäki, J; Tuomilehto, J; Uusitupa, M; Valle, TT	1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW	3
Cleary, P; Dahms, W; Genuth, S; Malone, J; Monnier, VM; Sell, DR; Sivitz, W; Sun, W	1
Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G	1
Niwa, T; Taki, K; Tsuruta, Y	1
Altshuler, D; Dabelea, D; Florez, JC; Franks, PW; Hamman, RF; Jablonski, KA; Kahn, SE; Knowler, WC; Nathan, DM	1
Helanterä, A; Huoponen, K; Jahnukainen, T; Kananen, K; Keskinen, P; Linnanvuo, M; Metso, M; Näntö-Salonen, K; Niinikoski, H; Saha, H; Simell, O; Tanner, LM	1
Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S	1
Dwyer, E; Itescu, S; Rose, S; Winchester, R	1
Descamps-Latscha, B; Friedlander, MA; Jungers, P; Labrunte, M; Nguyen, AT; Verger, C; Witko-Sarsat, V; Wu, YC	1
Hricik, DE; Justice, AC; Rodby, RA; Weiss, MF	1
Arai, K; Chikuda, M; Hashimoto, H; Obara, Y	1
Birlouez-Aragon, I; Junes, P; Mondon, H; Moreaux, V; Tessier, F	1
Chen, JR; Inoue, T; Kushida, K; Miyamoto, S; Suzuki, M; Takahashi, M	1
Connor, JR; Currie, MG; Fernandes, JC; Jovanovic, DV; Lascau-Coman, V; Manning, PT; Martel-Pelletier, J; Pelletier, JP	1
Abe, N; Baba, A; Kadowaki, T; Nakayama, K; Okamoto, K; Ratnayake, DB; Shi, Y; Yamamoto, K	1
Benghuzzi, H; Cason, Z; Higdon, K; Hughes, J; Puckett, A; Scott, A; Tsao, A; Tucci, M	1

Reviews

5 review(s) available for lysine and Disease Exacerbation

Article	Year
Epigenetics: an emerging player in gastric cancer. World journal of gastroenterology, 2014, Jun-07, Volume: 20, Issue:21 Topics: Chromatin; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; MicroRNAs; Neoplasm Metastasis; Nucleosomes; RNA, Long Noncoding; Stomach Neoplasms	2014
The role of microRNAs in diabetic nephropathy. Journal of diabetes research, 2014, Volume: 2014 Topics: Acetylation; Animals; Chromatin; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dogs; Epigenesis, Genetic; Epigenomics; Histones; Humans; Inflammation; Kidney; Lysine; Methylation; Mice; Mice, Transgenic; MicroRNAs; Rats	2014
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk. Rejuvenation research, 2015, Volume: 18, Issue:1 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disease Progression; Humans; Inflammation; Ligands; Lysine; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Oxidative Stress; Receptor for Advanced Glycation End Products; Risk Factors; Treatment Outcome	2015
Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases. Annals of the New York Academy of Sciences, 2010, Volume: 1201 Topics: Acetylation; Animals; Disease Progression; DNA, Mitochondrial; Electron Transport; Humans; Lysine; Mitochondria; Mitochondrial Diseases; Mutation; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Syndrome; Ubiquitin	2010
Porphyromonas gingivalis proteinases as virulence determinants in progression of periodontal diseases. Journal of biochemistry, 2000, Volume: 128, Issue:2 Topics: Adhesins, Bacterial; Animals; Arginine; Cysteine Endopeptidases; Disease Progression; Gingipain Cysteine Endopeptidases; Hemagglutinins; Humans; Lysine; Mutation; Periodontal Diseases; Porphyromonas gingivalis; Virulence	2000

Trials

6 trial(s) available for lysine and Disease Exacerbation

Article	Year
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine. PloS one, 2013, Volume: 8, Issue:5 Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2013
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes. Cardiovascular diabetology, 2015, Sep-05, Volume: 14 Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chi-Square Distribution; Collagen; Coronary Artery Disease; Diabetes Mellitus, Type 1; Disease Progression; Female; Glycation End Products, Advanced; Glycosylation; Heart Diseases; Humans; Logistic Models; Lysine; Magnetic Resonance Imaging; Male; Multivariate Analysis; Odds Ratio; Pepsin A; Pyruvaldehyde; Risk Factors; Skin; Time Factors; Vascular Calcification; Young Adult	2015
In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients. Clinical and experimental immunology, 2010, Volume: 161, Issue:2 Topics: Adjuvants, Immunologic; Aged; Breast Neoplasms; Cell Proliferation; Chemokines; Cytokines; Diphosphonates; Disease Progression; Esterases; Female; Hemiterpenes; Humans; Imidazoles; Immunotherapy; Interferon-gamma; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Count; Lysine; Middle Aged; Mucin-1; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Salvage Therapy; T-Lymphocyte Subsets; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Tumor Necrosis Factor Receptor Superfamily, Member 7; Zoledronic Acid	2010
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:12 Topics: Adenine; Adult; Alleles; ATP-Binding Cassette Transporters; Confidence Intervals; Diabetes Mellitus, Type 2; Disease Progression; Genetic Predisposition to Disease; Glucose Intolerance; Guanine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Middle Aged; Odds Ratio; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Receptors, Drug; Sulfonylurea Receptors	2004
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program. Diabetes, 2007, Volume: 56, Issue:2 Topics: Alleles; ATP-Binding Cassette Transporters; Diabetes Mellitus, Type 2; Disease Progression; Female; Genetic Predisposition to Disease; Genotype; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lysine; Male; Metformin; Middle Aged; Mutation, Missense; Polymorphism, Genetic; Potassium Channels; Potassium Channels, Inwardly Rectifying; Proportional Hazards Models; Receptors, Drug; Sulfonylurea Receptors; Treatment Outcome	2007
Free pentosidine and neopterin as markers of progression rate in diabetic nephropathy. Collaborative Study Group. Kidney international, 1998, Volume: 54, Issue:1 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Captopril; Creatinine; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progression; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Lysine; Male; Neopterin; Predictive Value of Tests; Survival Analysis	1998

Other Studies

97 other study(ies) available for lysine and Disease Exacerbation

Article	Year
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53. Cell death & disease, 2021, 10-14, Volume: 12, Issue:10 Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Protein Domains; Protein Stability; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Treatment Outcome; Tripartite Motif Proteins; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination	2021
ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis. Cell death & disease, 2021, 10-18, Volume: 12, Issue:11 Topics: Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; ets-Domain Protein Elk-4; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Receptor, Notch1; RNA, Long Noncoding; Stomach Neoplasms; Up-Regulation	2021
Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 2022, 01-25, Volume: 119, Issue:4 Topics: Animals; Antigens, Surface; Binding Sites; Cell Cycle Proteins; Disease Models, Animal; Disease Progression; Fluorescent Antibody Technique; Fluorescent Dyes; Gene Expression; Glutamate Carboxypeptidase II; Glutamates; Humans; Immunohistochemistry; Lysine; Male; Mice; Models, Molecular; Molecular Conformation; Molecular Imaging; Molecular Probes; Prostatic Neoplasms; Protein Binding; Receptors, Kainic Acid; Structure-Activity Relationship; Urea	2022
Leukemia inhibitory factor receptor homodimerization mediated by acetylation of extracellular lysine promotes prostate cancer progression through the PDPK1/AKT/GCN5 axis. Clinical and translational medicine, 2022, Volume: 12, Issue:2 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Acetylation; Animals; Disease Progression; Lysine; Male; Mice; Prostatic Neoplasms; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, OSM-LIF	2022
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis. Cell reports, 2019, 11-05, Volume: 29, Issue:6 Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Databases, Genetic; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational	2019
PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:3 Topics: Aerobiosis; Aged; Caco-2 Cells; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Colorectal Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Hexokinase; HT29 Cells; Humans; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Up-Regulation	2020
Identification of Differential Patterns of Oxidative Biomarkers in Prostate Cancer Progression. Clinical genitourinary cancer, 2020, Volume: 18, Issue:2 Topics: Aged; Aged, 80 and over; Biomarkers; Disease Progression; F2-Isoprostanes; Follow-Up Studies; Humans; Kallikreins; Lysine; Male; Middle Aged; Oxidative Stress; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Risk Assessment; Watchful Waiting	2020
miR24-2 accelerates progression of liver cancer cells by activating Pim1 through tri-methylation of Histone H3 on the ninth lysine. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:5 Topics: Animals; Base Sequence; Cell Line, Tumor; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Liver Neoplasms; Lysine; Male; Methylation; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Models, Biological; Oncogenes; Proto-Oncogene Proteins c-pim-1	2020
Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression. International journal of molecular sciences, 2020, Feb-27, Volume: 21, Issue:5 Topics: Animals; Cell Proliferation; Chromatin Immunoprecipitation; Chromatography, Liquid; Disease Progression; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Lysine Acetyltransferase 5; Male; Methylation; Mice; Mice, Nude; Nuclear Receptor Subfamily 1, Group F, Member 1; Oncogenes; PC-3 Cells; Prostatic Neoplasms; Protein Binding; Protein Domains; Protein Isoforms; Tandem Mass Spectrometry; Trans-Activators	2020
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. The Journal of experimental medicine, 2020, 05-04, Volume: 217, Issue:5 Topics: Acetylation; Aged; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Disease Progression; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Interferons; Lysine; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Middle Aged; Neoplastic Stem Cells; Promoter Regions, Genetic; STAT1 Transcription Factor; Up-Regulation	2020
LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter. Cell death & disease, 2020, 05-04, Volume: 11, Issue:5 Topics: Carcinogenesis; Cell Line; Class Ib Phosphatidylinositol 3-Kinase; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; Retinoblastoma; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic	2020
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling. Development (Cambridge, England), 2020, 06-15, Volume: 147, Issue:21 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cerebellum; Cytoplasmic Granules; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Lysine; Medulloblastoma; Mice, Inbred C57BL; Mice, Knockout; Neural Stem Cells; Polycomb Repressive Complex 2; Polyubiquitin; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays	2020
Connectivity mapping of a chronic kidney disease progression signature identified lysine deacetylases as novel therapeutic targets. Kidney international, 2020, Volume: 98, Issue:1 Topics: Animals; Disease Progression; Fibrosis; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Lysine; Mice; Renal Insufficiency, Chronic	2020
Prostate Cancer Lymphangitic Pulmonary Carcinomatosis: Appearance on 18F-FDG PET/CT and 18F-DCFPyL PET/CT. Clinical nuclear medicine, 2020, Volume: 45, Issue:9 Topics: Disease Progression; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Lysine; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Prednisone; Prostatic Neoplasms; Urea	2020
Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. Aging, 2020, 07-17, Volume: 12, Issue:14 Topics: Acetylation; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; CREB-Binding Protein; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lysine; Male; Mice; Mice, Knockout; Neoplasm Invasiveness; Peroxisomal Multifunctional Protein-2; Prostatic Neoplasms; Sirtuin 3; Testosterone; Xenograft Model Antitumor Assays	2020
E6 hijacks KDM5C/lnc_000231/miR-497-5p/CCNE1 axis to promote cervical cancer progression. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:19 Topics: Acetylation; Animals; Base Sequence; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Oncogene Proteins; Oncogene Proteins, Viral; Promoter Regions, Genetic; Protein Stability; RNA, Long Noncoding; Tumor Stem Cell Assay; Up-Regulation; Uterine Cervical Neoplasms	2020
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20 Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms	2020
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia. Oncogene, 2020, Volume: 39, Issue:50 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic	2020
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level. Cell communication and signaling : CCS, 2020, 10-27, Volume: 18, Issue:1 Topics: Animals; Carcinogenesis; CDX2 Transcription Factor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multivariate Analysis; Nuclear Proteins; Promoter Regions, Genetic; Repressor Proteins; Survival Analysis; Up-Regulation; Wnt Signaling Pathway	2020
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer. Biomolecules, 2020, 12-16, Volume: 10, Issue:12 Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Ovarian Neoplasms; Prognosis; Quinazolines; RNA, Small Interfering; Transfection; Up-Regulation	2020
Overexpression of ring finger protein 20 inhibits the progression of liver fibrosis via mediation of histone H2B lysine 120 ubiquitination. Human cell, 2021, Volume: 34, Issue:3 Topics: Cell Movement; Cell Survival; Cells, Cultured; Disease Progression; Gene Expression; Histones; Humans; Interleukin-6; Liver Cirrhosis; Lysine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ubiquitination; Vascular Endothelial Growth Factor A	2021
SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs. Nucleic acids research, 2021, 03-18, Volume: 49, Issue:5 Topics: Adenosine; Animals; Cell Hypoxia; Cell Line; Disease Progression; Humans; Lysine; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oxidative Stress; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcriptome; Ubiquitination	2021
RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nature communications, 2021, 02-16, Volume: 12, Issue:1 Topics: Animals; Arginine; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Female; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Lysine; Mechanistic Target of Rapamycin Complex 1; Mice, Nude; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Ubiquitin-Protein Ligases; Ubiquitination	2021
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters. Cell death & disease, 2021, 07-23, Volume: 12, Issue:8 Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay	2021
TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination. Cell death & disease, 2017, 05-25, Volume: 8, Issue:5 Topics: Animals; Apoptosis; Biocatalysis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Protein Stability; Repressor Proteins; RNA, Messenger; Signal Transduction; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination	2017
Loss of Asxl2 leads to myeloid malignancies in mice. Nature communications, 2017, 06-08, Volume: 8 Topics: Animals; Cell Lineage; Cell Self Renewal; Disease Progression; Gene Deletion; Gene Expression Regulation, Leukemic; Hematopoiesis; Hematopoietic Stem Cells; Histones; Leukemia, Myeloid, Acute; Lysine; Mice; Myelodysplastic Syndromes; Myeloid Cells; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic	2017
SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis. Molecular cancer, 2017, 10-11, Volume: 16, Issue:1 Topics: Base Composition; Carcinogenesis; Cell Line, Tumor; Disease Progression; Humans; Hydrogen Peroxide; Hypoxia; Lysine; MicroRNAs; Models, Biological; Nucleic Acid Conformation; Protein Binding; Protein Transport; RNA-Binding Proteins; SUMO-1 Protein; Sumoylation; Terminal Repeat Sequences; Trans-Activators	2017
Src SUMOylation Inhibits Tumor Growth Via Decreasing FAK Y925 Phosphorylation. Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:12 Topics: Animals; Cell Line; Disease Progression; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysine; Mice; Models, Molecular; Mutation; Neoplasms; Phosphorylation; Protein Conformation; src-Family Kinases; Sumoylation	2017
CML/CD36 accelerates atherosclerotic progression via inhibiting foam cell migration. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97 Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Cell Migration Inhibition; Cell Movement; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Foam Cells; Glycation End Products, Advanced; Lysine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells	2018
The advanced glycation end-product N The Journal of pathology, 2018, Volume: 245, Issue:2 Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Diabetes Complications; Disease Models, Animal; Disease Progression; Genes, ras; Humans; Lysine; Mice, Inbred C57BL; Mice, Transgenic; Pancreatic Neoplasms; Peptides; Receptor for Advanced Glycation End Products; Risk Factors; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays	2018
HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression. Cancer letters, 2018, 07-10, Volume: 426 Topics: Acetylation; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Disease Progression; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HeLa Cells; Homeodomain Proteins; Humans; Lysine; Male; MCF-7 Cells; Prognosis; Survival Analysis	2018
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation. Cell death & disease, 2018, 05-22, Volume: 9, Issue:6 Topics: Anoikis; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Models, Biological; Neoplasm Invasiveness; Polyubiquitin; Proteolysis; Snail Family Transcription Factors; Tripartite Motif Proteins; Tumor Stem Cell Assay; Ubiquitin-Protein Ligases; Ubiquitination	2018
Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy. Journal of molecular medicine (Berlin, Germany), 2018, Volume: 96, Issue:7 Topics: Adult; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Diabetic Nephropathies; Disease Progression; Epithelial Cells; Female; Fluorescent Antibody Technique; Gene Expression; Gene Silencing; Humans; Hyperglycemia; Immunohistochemistry; Kidney Tubules; Lysine; Male; Microtubule-Associated Proteins; Middle Aged; Ubiquitination	2018
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis. Journal of Crohn's & colitis, 2018, Nov-15, Volume: 12, Issue:11 Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult	2018
Quantitative proteome and lysine succinylome analyses provide insights into metabolic regulation in breast cancer. Breast cancer (Tokyo, Japan), 2019, Volume: 26, Issue:1 Topics: Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Computational Biology; Disease Progression; Female; Humans; Lysine; Middle Aged; Protein Processing, Post-Translational; Proteome; Proteomics; Succinic Acid; Tandem Mass Spectrometry	2019
[Genetic Creutzfeldt-Jakob disease with a glutamate-to-lysine substitution at codon 219 (E219K) in the presence of the E200K mutation presenting with rapid progressive dementia following slowly progressive clinical course]. Rinsho shinkeigaku = Clinical neurology, 2018, Nov-28, Volume: 58, Issue:11 Topics: 14-3-3 Proteins; Alleles; Amino Acid Substitution; Biomarkers; Brain; Codon; Creutzfeldt-Jakob Syndrome; Diffusion Magnetic Resonance Imaging; Disease Progression; Electroencephalography; Frontotemporal Dementia; Glutamates; Humans; Lysine; Male; Middle Aged; Mutation; Polymorphism, Genetic; Prion Proteins; tau Proteins	2018
Methylglyoxal as a prognostic factor in patients with chronic kidney disease. Nephrology (Carlton, Vic.), 2019, Volume: 24, Issue:9 Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Deoxyglucose; Diabetic Nephropathies; Disease Progression; Female; Humans; Japan; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvaldehyde; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Up-Regulation	2019
Lysine crotonylation is involved in hepatocellular carcinoma progression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111 Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Liver Neoplasms; Lysine; Mice; Mice, Inbred C57BL; Protein Processing, Post-Translational; Up-Regulation	2019
Circulating and Extracellular Vesicles Levels of N-(1-Carboxymethyl)-L-Lysine (CML) Differentiate Early to Moderate Alzheimer's Disease. Journal of Alzheimer's disease : JAD, 2019, Volume: 69, Issue:3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Biomarkers; Cell Line; Diagnosis, Differential; Disease Progression; Extracellular Vesicles; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Mental Status and Dementia Tests; Neurons	2019
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter. Nature communications, 2019, 06-03, Volume: 10, Issue:1 Topics: Acetylation; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Drug Resistance, Neoplasm; Humans; In Vitro Techniques; Lysine; MCF-7 Cells; Mice; Mutation; Neoplasm Transplantation; Peroxidase; Protein Structure, Quaternary; Reactive Oxygen Species; Superoxide Dismutase; Tamoxifen; Tumor Suppressor Proteins	2019
Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma. Frontiers of medicine, 2020, Volume: 14, Issue:1 Topics: Acetylation; Adult; Aged; Aged, 80 and over; Carcinoma, Pancreatic Ductal; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Protein Processing, Post-Translational	2020
Skin pentosidine in very early hip/knee osteoarthritis (CHECK) is not a strong independent predictor of radiographic progression over 5 years follow-up. Osteoarthritis and cartilage, 2013, Volume: 21, Issue:6 Topics: Aged; Arginine; Chromatography, High Pressure Liquid; Collagen Type II; Cross-Sectional Studies; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Lysine; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteophyte; Radiography; Skin	2013
Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population: a 3-year follow-up of the ROAD study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014, Volume: 25, Issue:3 Topics: Age Distribution; Aged; Aged, 80 and over; Anthropometry; Arginine; Biomarkers; Bone Density; Comorbidity; Disease Progression; Female; Femur Neck; Follow-Up Studies; Humans; Hyperostosis, Diffuse Idiopathic Skeletal; Japan; Lumbar Vertebrae; Lysine; Male; Middle Aged; Ossification of Posterior Longitudinal Ligament; Prevalence; Radiography; Sex Distribution	2014
The polycomb group protein EZH2 inhibits lung cancer cell growth by repressing the transcription factor Nrf2. FEBS letters, 2014, Aug-25, Volume: 588, Issue:17 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Histones; Humans; Lung Neoplasms; Lysine; Male; Methylation; Middle Aged; NF-E2-Related Factor 2; Polycomb Repressive Complex 2; Survival Analysis	2014
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nature communications, 2014, Aug-06, Volume: 5 Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors	2014
The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis. Molecular cancer, 2014, Aug-12, Volume: 13 Topics: Animals; Anoikis; Biomarkers, Tumor; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mice, Inbred NOD; Mice, SCID; Multivariate Analysis; Neoplasm Invasiveness; Ovarian Neoplasms; Peritoneal Neoplasms; Prognosis; Signal Transduction	2014
Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters. Journal of Alzheimer's disease : JAD, 2015, Volume: 45, Issue:1 Topics: Aged; Alzheimer Disease; Arginine; Blood Glucose; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Humans; Insulin; Insulin Resistance; Lysine; Male; Malondialdehyde; Neuropsychological Tests; Psychiatric Status Rating Scales; Statistics as Topic	2015
Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes. Diabetes care, 2015, Volume: 38, Issue:4 Topics: Autoantibodies; Case-Control Studies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Disease Progression; Down-Regulation; Female; Humans; Infant; Infant, Newborn; Lysine; Male; Prediabetic State; Receptor for Advanced Glycation End Products; Receptors, Immunologic	2015
Glycation of human cortical and cancellous bone captures differences in the formation of Maillard reaction products between glucose and ribose. PloS one, 2015, Volume: 10, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arginine; Disease Progression; Female; Glucose; Glycation End Products, Advanced; Glycosylation; Humans; Kinetics; Lysine; Maillard Reaction; Male; Middle Aged; Models, Molecular; Osteocalcin; Protein Conformation; Ribose; Tibia	2015
Alternation of histone and DNA methylation in human atherosclerotic carotid plaques. Thrombosis and haemostasis, 2015, Volume: 114, Issue:2 Topics: Aged; Blood Cells; Carotid Arteries; Carotid Artery Diseases; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Induction; Female; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Inflammation; Leukocytes; Long Interspersed Nucleotide Elements; Lysine; Macrophages; Male; Methylation; Middle Aged; Mixed Function Oxygenases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neoplasm Proteins; Plaque, Atherosclerotic; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction	2015
The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study. Cardiovascular diabetology, 2015, Jul-28, Volume: 14 Topics: Aged; Amputation, Surgical; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Disease-Free Survival; Female; Humans; Incidence; Kaplan-Meier Estimate; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Risk Assessment; Risk Factors; S100A12 Protein; Sweden; Time Factors	2015
Protein-Bound Plasma Nε-(Carboxymethyl)lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation: The Hoorn and CODAM Studies. Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:12 Topics: Absorptiometry, Photon; Adiposity; Adult; Aged; Biomarkers; Body Mass Index; Chromatography, Liquid; Cross-Sectional Studies; Disease Progression; Female; Humans; Inflammation; Inflammation Mediators; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Obesity, Abdominal; Obesity, Morbid; Prospective Studies; Risk Factors; Tandem Mass Spectrometry; Waist Circumference	2015
Skin collagen pentosidine and fluorescence in diabetes were predictors of retinopathy progression and creatininemia increase already 6years after punch-biopsy. Clinical biochemistry, 2016, Volume: 49, Issue:3 Topics: Adult; Albuminuria; Arginine; Biomarkers; Biopsy; Case-Control Studies; Collagen; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Female; Fluorescence; Humans; Longitudinal Studies; Lysine; Male; Middle Aged; Skin; Spectrometry, Fluorescence	2016
High serum pentosidine in branch atheromatous disease among small vessels occlusion. Journal of neurosurgical sciences, 2019, Volume: 63, Issue:4 Topics: Aged; Aged, 80 and over; Arginine; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Disease Progression; Female; Humans; Lysine; Male; Middle Aged; Plaque, Atherosclerotic; Prognosis; Risk Factors; Sensitivity and Specificity	2019
Increased levels of N(ε)- Carboxy methyl lysine (N(ε)-CML) are associated with topographic alterations in retinal pigment epithelium: A preliminary study. Journal of diabetes and its complications, 2016, Volume: 30, Issue:5 Topics: Adult; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Glycated Hemoglobin; Humans; Lysine; Male; Middle Aged; Prospective Studies; Regression Analysis; Retinal Pigment Epithelium; Severity of Illness Index; Tertiary Care Centers; Up-Regulation; Vitreoretinopathy, Proliferative	2016
The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. Oncogene, 2016, 10-06, Volume: 35, Issue:40 Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diamines; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Male; Mice; Middle Aged; Neoplasm Metastasis; Oxidoreductases Acting on CH-NH Group Donors; rhoA GTP-Binding Protein; Signal Transduction	2016
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition. Cell reports, 2016, 06-21, Volume: 15, Issue:12 Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes	2016
Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis. Nature communications, 2016, 07-14, Volume: 7 Topics: Amino Acid Sequence; Animals; Bile Acids and Salts; Cell Nucleus; Cholestasis; Disease Progression; Down-Regulation; Epigenesis, Genetic; Hep G2 Cells; Homeostasis; Humans; Liver; Lysine; Male; Mice, Inbred BALB C; Models, Biological; Molecular Chaperones; Mutation; Nuclear Pore Complex Proteins; Phosphorylation; Phosphothreonine; Protein Binding; Protein Transport; Receptors, Cytoplasmic and Nuclear; Small Ubiquitin-Related Modifier Proteins; Sumoylation	2016
DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop. Experimental cell research, 2016, 08-15, Volume: 346, Issue:2 Topics: Antigens, CD; Base Sequence; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Chromatin; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; MicroRNAs; Neoplasm Grading; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; RNA, Small Interfering; Transfection; Wound Healing	2016
Imbalance of plasma amino acids, metabolites and lipids in patients with lysinuric protein intolerance (LPI). Metabolism: clinical and experimental, 2016, Volume: 65, Issue:9 Topics: Adolescent; Adult; Aged; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Essential; Carbohydrate Metabolism; Child; Disease Progression; Energy Metabolism; Female; Finland; Glomerular Filtration Rate; Humans; Lipid Metabolism; Lipids; Lysine; Male; Middle Aged; Nitrites; Phosphatidylcholines; Triglycerides; Young Adult	2016
The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation. Molecular cell, 2016, 09-15, Volume: 63, Issue:6 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Lysine; MCF-7 Cells; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplastic Stem Cells; Nuclear Proteins; RNA, Small Interfering; Signal Transduction; Survival Analysis; Twist-Related Protein 1; Ubiquitin-Protein Ligases; Ubiquitination	2016
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression. Oncogene, 2017, Volume: 36, Issue:15 Topics: Breast Neoplasms; Cell Line, Tumor; CRISPR-Cas Systems; Disease Progression; Evolution, Molecular; Female; Gene Knockout Techniques; HSP90 Heat-Shock Proteins; Humans; Lysine; Structure-Activity Relationship	2017
The F-box protein FBXL18 promotes glioma progression by promoting K63-linked ubiquitination of Akt. FEBS letters, 2017, Volume: 591, Issue:1 Topics: Apoptosis; Bcl-2-Like Protein 11; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression; F-Box Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Humans; Lysine; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Ubiquitination; Up-Regulation	2017
Chemical Isotope Labeling LC-MS for Monitoring Disease Progression and Treatment in Animal Models: Plasma Metabolomics Study of Osteoarthritis Rat Model. Scientific reports, 2017, 01-16, Volume: 7 Topics: Animals; Biomarkers; Chromatography, Liquid; Discriminant Analysis; Disease Models, Animal; Disease Progression; Isotope Labeling; Joints; Least-Squares Analysis; Lysine; Metabolome; Metabolomics; Osteoarthritis; Principal Component Analysis; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2017
Clinical and histopathological features of progressive-type familial amyloidotic polyneuropathy with TTR Lys54. Journal of the neurological sciences, 2009, Jan-15, Volume: 276, Issue:1-2 Topics: 3-Iodobenzylguanidine; Adult; Amyloid Neuropathies, Familial; Autopsy; Disease Progression; Female; Glucose Tolerance Test; Humans; Lysine; Male; Mutation; Myocardial Perfusion Imaging; Peripheral Nerves; Prealbumin; Sural Nerve	2009
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science (New York, N.Y.), 2008, Dec-12, Volume: 322, Issue:5908 Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors	2008
Pentosidine - a new biochemical marker in diabetic retinopathy. Ophthalmic research, 2009, Volume: 42, Issue:2 Topics: Adult; Arginine; Biomarkers; Blood Glucose; Blood Proteins; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Disease Progression; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged	2009
L-2-hydroxyglutaric aciduria diagnosed in an adult presenting with acute deterioration. Journal of neurology, 2010, Volume: 257, Issue:1 Topics: Adult; Ataxia; Brain; Disease Progression; Epilepsy; Glutarates; Humans; Lysine; Male; Metabolism, Inborn Errors; Rare Diseases; Seizures	2010
Diagnosis of aspirin-induced asthma combining the bronchial and the oral challenge tests: a pilot study. Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:6 Topics: Administration, Oral; Adult; Allergens; Aspirin; Asthma, Aspirin-Induced; Bronchial Provocation Tests; Cross-Sectional Studies; Disease Progression; Female; Humans; Immunization; Lysine; Male; Middle Aged; Nasal Polyps; Pilot Projects; Predictive Value of Tests	2009
HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2011, Volume: 40, Issue:7 Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Gene Expression Profiling; Gene Knockdown Techniques; Histone Deacetylase 2; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphatic Metastasis; Lysine; Mice; Mice, SCID; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Transplantation; Protein Processing, Post-Translational; Protein Stability; Random Allocation; Ubiquitination; Von Hippel-Lindau Tumor Suppressor Protein	2011
Mass spectrometric identification of novel lysine acetylation sites in huntingtin. Molecular & cellular proteomics : MCP, 2011, Volume: 10, Issue:10 Topics: Acetylation; Animals; Antibodies; Brain; Disease Progression; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Huntingtin Protein; Huntington Disease; Lysine; Mass Spectrometry; Mice; Nerve Tissue Proteins; Nuclear Proteins; Protein Processing, Post-Translational; Protein Structure, Tertiary	2011
Initial neuropsychological impairments in patients with the E46K mutation of the α-synuclein gene (PARK 1). Journal of the neurological sciences, 2011, Nov-15, Volume: 310, Issue:1-2 Topics: Aged; Aged, 80 and over; alpha-Synuclein; Cognition Disorders; Disease Progression; Family Health; Female; Glutamine; Humans; Longitudinal Studies; Lysine; Male; Mutation; Neuropsychological Tests; Parkinson Disease; Psychiatric Status Rating Scales; Time Factors	2011
Idiopathic carbonyl stress in a drug-naive case of at-risk mental state. Psychiatry and clinical neurosciences, 2011, Volume: 65, Issue:6 Topics: Arginine; Disease Progression; Humans; Lysine; Male; Mental Disorders; Oxidative Stress; Young Adult	2011
Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes. Atherosclerosis, 2012, Volume: 221, Issue:2 Topics: Alkaline Phosphatase; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Core Binding Factor Alpha 2 Subunit; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diet, High-Fat; Disease Progression; Glucose; Immunohistochemistry; Injections, Intravenous; Lipoproteins, LDL; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteogenesis; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Staining and Labeling; Time Factors; Vascular Calcification	2012
Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response. Journal of reproductive immunology, 2012, Volume: 93, Issue:2 Topics: Adult; Biomarkers; Disease Progression; Female; Follow-Up Studies; HMGB1 Protein; Humans; Inflammation; Inflammation Mediators; Ligands; Lysine; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; S100A12 Protein	2012
Lysine triggers apoptosis through a NADPH oxidase-dependent mechanism in human renal tubular cells. Journal of inherited metabolic disease, 2012, Volume: 35, Issue:6 Topics: Amino Acid Metabolism, Inborn Errors; Antioxidants; Apoptosis; Caspase Inhibitors; Cell Line; Disease Progression; Gene Expression; Humans; Kidney Tubules, Proximal; Lysine; Membrane Potential, Mitochondrial; NADPH Oxidases; Protein Subunits; Reactive Oxygen Species; Renal Insufficiency, Chronic	2012
Adult manifestation of L-2-hydroxyglutarate dehydrogenase deficiency by a novel mutation. Neurology, 2012, Apr-10, Volume: 78, Issue:15 Topics: Adult; Alcohol Oxidoreductases; Brain; Cerebellar Diseases; Cognition Disorders; Disease Progression; Female; Humans; Lysine; Magnetic Resonance Imaging; Mutation; Saccades; Tremor	2012
Enhanced levels of non-enzymatic glycation and pentosidine crosslinking in spontaneous osteoarthritis progression. Osteoarthritis and cartilage, 2012, Volume: 20, Issue:7 Topics: Animals; Arginine; Arthritis, Experimental; Bone Density; Cartilage, Articular; Collagen; Disease Progression; Glycation End Products, Advanced; Guinea Pigs; Injections, Intra-Articular; Lysine; Male; Osteoarthritis; Ribose; X-Ray Microtomography	2012
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature, 2012, Jul-05, Volume: 487, Issue:7405 Topics: Acetylation; Adenovirus E1A Proteins; Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chromatin; Contact Inhibition; Disease Progression; ets-Domain Protein Elk-4; Histone Deacetylases; Histones; Humans; Lysine; Mice; Neoplasm Transplantation; Nucleotide Motifs; Phenotype; Promoter Regions, Genetic; Repressor Proteins; Sirtuins; Transcription, Genetic; Transplantation, Heterologous	2012
Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49 Topics: Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Lysine; Neoplasms; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; ras Proteins; RNA, Small Interfering; Signal Transduction	2012
Malignant tumor disease as a sub-chronic, progressive intoxication on the basis of the perpetuation of the release of amino acids, initiated by a retrograde-differentiated muscle degradation protease. Medical hypotheses, 2002, Volume: 59, Issue:5 Topics: Amino Acids; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Progression; Endopeptidases; Humans; Lysine; Models, Biological; Muscle Proteins; Muscle, Skeletal; Neoplasm Proteins; Neoplasms; Nutrition Disorders	2002
Hyaluronic acid levels may have predictive value for the progression of knee osteoarthritis. Osteoarthritis and cartilage, 2004, Volume: 12, Issue:4 Topics: Adipokines; Adjuvants, Immunologic; Arginine; Biomarkers; Cartilage Oligomeric Matrix Protein; Cartilage, Articular; Chitinase-3-Like Protein 1; Cross-Linking Reagents; Disease Progression; Extracellular Matrix Proteins; Female; Glycoproteins; Humans; Hyaluronic Acid; Knee Joint; Lectins; Lysine; Male; Matrilin Proteins; Matrix Metalloproteinase 9; Middle Aged; Osteoarthritis, Knee; Prognosis; Radiography; Tissue Inhibitor of Metalloproteinases	2004
In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry. Oncology reports, 2005, Volume: 13, Issue:3 Topics: Animals; Antioxidants; Ascorbic Acid; Colonic Neoplasms; Diet; Disease Progression; Immunohistochemistry; Ki-67 Antigen; Lysine; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Mucins; Neoplasms, Experimental; Proline; Tea; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2005
In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7. Medical oncology (Northwood, London, England), 2005, Volume: 22, Issue:2 Topics: Animals; Antioxidants; Ascorbic Acid; Collagen; Disease Progression; Drug Combinations; Drug Synergism; Female; Humans; Immunoenzyme Techniques; In Vitro Techniques; Laminin; Lysine; Mammary Neoplasms, Experimental; Matrix Metalloproteinases; Mice; Mice, Nude; Proline; Proteoglycans; Tea; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2005
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications p Diabetes, 2005, Volume: 54, Issue:11 Topics: Adult; Biopsy; Collagen; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Disease Susceptibility; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Prognosis; Skin; Time Factors	2005
Antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on bladder cancer cell line T-24. International journal of urology : official journal of the Japanese Urological Association, 2006, Volume: 13, Issue:4 Topics: Antioxidants; Arginine; Ascorbic Acid; Biomarkers, Tumor; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Humans; In Vitro Techniques; Lysine; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Plant Extracts; Proline; Urinary Bladder Neoplasms	2006
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:4 Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors	2006
Indoxyl sulfate and atherosclerotic risk factors in hemodialysis patients. American journal of nephrology, 2007, Volume: 27, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Atherosclerosis; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Chromatography, High Pressure Liquid; Creatinine; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Incidence; Indican; Lysine; Male; Middle Aged; Nephelometry and Turbidimetry; Renal Dialysis; Uremia	2007
Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intolerance. The Journal of pediatrics, 2007, Volume: 150, Issue:6 Topics: Adolescent; Adult; Amino Acid Transport Disorders, Inborn; Child; Child, Preschool; Citrulline; Creatinine; Cystatin C; Cystatins; Disease Progression; Female; Glomerular Filtration Rate; Humans; Infant; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Male; Middle Aged; Proteinuria	2007
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:4 Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta	2008
Grouping HLA-B locus serologic specificities according to shared structural motifs suggests that different peptide-anchoring pockets may have contrasting influences on the course of HIV-1 infection. Human immunology, 1995, Volume: 42, Issue:1 Topics: Adult; AIDS-Related Opportunistic Infections; Antigen Presentation; Binding Sites; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Child; Disease Progression; Disease Susceptibility; Gene Frequency; Genetic Predisposition to Disease; HIV Infections; HIV-1; HLA-B Antigens; HLA-B35 Antigen; Humans; Lymphocyte Count; Lysine; Peptide Fragments; Protein Binding; Protein Conformation	1995
The advanced glycation endproduct pentosidine and monocyte activation in uremia. Clinical nephrology, 1996, Volume: 45, Issue:6 Topics: Arginine; Biomarkers; Biopterins; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Disease Progression; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Monocytes; Neopterin; Peritoneal Dialysis; Radioimmunoassay; Renal Dialysis; Uremia	1996
[Relationship between vascular endothelial growth factors and advanced glycation end products in the human vitreous]. Nippon Ganka Gakkai zasshi, 1998, Volume: 102, Issue:7 Topics: Adult; Arginine; Cytokines; Diabetic Retinopathy; Disease Progression; Endothelial Growth Factors; Glycation End Products, Advanced; Humans; Lymphokines; Lysine; Middle Aged; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitreous Body	1998
Decrease in vitamin C concentration in human lenses during cataract progression. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1998, Volume: 68, Issue:5 Topics: Ascorbic Acid; Cataract; Disease Progression; Female; Fructose; Humans; Lens Nucleus, Crystalline; Lysine; Male; Sensitivity and Specificity; Tryptophan	1998
Pentosidine in synovial fluid in osteoarthritis and rheumatoid arthritis: relationship with disease activity in rheumatoid arthritis. The Journal of rheumatology, 1998, Volume: 25, Issue:12 Topics: Adult; Aged; Anti-Inflammatory Agents; Arginine; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Diabetes Complications; Diabetes Mellitus; Disease Progression; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Osteoarthritis; Prednisolone; Severity of Illness Index; Steroids; Synovial Fluid	1998
Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level. Arthritis and rheumatism, 2000, Volume: 43, Issue:6 Topics: Animals; Apoptosis; Cartilage, Articular; Caspase 3; Caspases; Disease Progression; Dogs; Enzyme Inhibitors; Immunohistochemistry; Lysine; Matrix Metalloproteinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis; Proto-Oncogene Proteins c-bcl-2	2000
The prevention of osteoporotic progression by means of steroid loaded TCPL drug delivery systems. Biomedical sciences instrumentation, 2001, Volume: 37 Topics: Animals; Bone Resorption; Calcium Phosphates; Dehydroepiandrosterone; Diosgenin; Disease Progression; Drug Delivery Systems; Drug Implants; Estradiol; Female; Lysine; Osteoporosis; Ovariectomy; Phosphates; Rats; Rats, Sprague-Dawley	2001