Page last updated: 2024-08-17

lysine and Cystic Fibrosis

lysine has been researched along with Cystic Fibrosis in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (12.00)	18.7374
1990's	5 (20.00)	18.2507
2000's	5 (20.00)	29.6817
2010's	10 (40.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Henri, YT; Hou, X; Ma, X; Wang, Z; Wu, Q; Yao, R; Yu, L; Zhang, B; Zhao, G	1
Rowbotham, NJ; Smith, S	1
Bilton, D; Downey, DG; Eustace, JA; Gunaratnam, C; Haworth, CS; Jones, AM; Ketchell, RI; McKone, EF; Peckham, DG; Plant, BJ	1
Aquino, RP; Del Gaudio, P; Mencherini, T; Russo, P; Sansone, F; Stigliani, M	1
Attucci, S; Bréa, D; Diot, P; Dubois, AV; Gauthier, F; Gras, D; Hervé, V; Khelloufi, MK; Midoux, P; Ramphal, R; Si-Tahar, M	1
Rubin, BK	1
Despanie, J; Henderson, MJ; Henry, K; Kang, PW; Lee, S; McClure, ML; Schiffhauer, E; Sorscher, EJ; Walker, D; Wilson, L; Zeitlin, PL	1
Aquino, RP; Casciaro, R; Del Gaudio, P; Galietta, L; Garofalo, E; Incarnato, L; Manniello, MD; Minicucci, L; Russo, P; Stigliani, M; Zegarra-Moran, O	1
Kirkpatrick, P; O'Sullivan, BP; Yasothan, U	1
Elborn, JS; Parkins, MD	1
Plosker, GL	2
Chiari, M; Corradini, R; Cretich, M; Galaverna, G; Marchelli, R; Sforza, S; Tedeschi, T	1
Casals, T; Chillón, M; Dörk, T; Estivill, X; Nunes, V; Tümmler, B	1
Carson, MR; Teem, JL; Welsh, MJ	1
Dasgupta, B; King, M	1
Gillissen, A	1
Baran, D; Moës, AJ; Schoutens, A; Van Gansbeke, B; Vanderbist, F; Wery, B	1
Alton, EW; Colledge, WH; Evans, MJ; Farley, R; Ferrari, S; Geddes, DM; Kitson, C; Marriott, C; Parkins, DA; Scarpa, M; Steel, R; Wainwright, B	1
App, EM; Baran, D; Coffiner, M; Dab, I; King, M; Malfroot, A; Vanderbist, F	1
Aron, Y; Briand, P; Fajac, I; Grosse, S; Tremeau-Bravard, A	1
Bonin, A; Lasalle, R; Morin, CL; Roy, CC	1
Beards, F; Harris, A; Shackleton, S	1
Benke, PJ; Herrick, N; Pitot, HC	1
Mangos, JA; McSherry, NR	1

Reviews

4 review(s) available for lysine and Cystic Fibrosis

Article	Year
Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. The Cochrane database of systematic reviews, 2022, Nov-14, Volume: 11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Child, Preschool; Cystic Fibrosis; Humans; Lysine; Middle Aged; Quality of Life; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2022
Aztreonam lysine: a novel inhalational antibiotic for cystic fibrosis. Expert review of respiratory medicine, 2010, Volume: 4, Issue:4 Topics: Administration, Inhalation; Adult; Aerosols; Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Humans; Lysine; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Treatment Outcome	2010
Aztreonam lysine for inhalation solution: in cystic fibrosis. Drugs, 2010, Oct-01, Volume: 70, Issue:14 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Humans; Lysine; Pharmaceutical Solutions; Pseudomonas aeruginosa; Pseudomonas Infections	2010
[New perspectives of antioxidant therapy with thiols: nacystelyn]. Pneumologie (Stuttgart, Germany), 1996, Volume: 50 Suppl 3 Topics: Acetylcysteine; Antioxidants; Cystic Fibrosis; Expectorants; Humans; Lysine; Prodrugs	1996

Trials

2 trial(s) available for lysine and Cystic Fibrosis

Article	Year
Deposition of nacystelyn from a dry powder inhaler in healthy volunteers and cystic fibrosis patients. Drug development and industrial pharmacy, 2001, Volume: 27, Issue:3 Topics: Absorption; Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Analysis of Variance; Child; Cystic Fibrosis; Expectorants; Female; Humans; Lung; Lysine; Male; Powders; Radionuclide Imaging; Technetium; Tissue Distribution	2001
Dose-finding and 24-h monitoring for efficacy and safety of aerosolized Nacystelyn in cystic fibrosis. The European respiratory journal, 2002, Volume: 19, Issue:2 Topics: Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Aerosols; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Female; Humans; Lysine; Male; Nebulizers and Vaporizers; Respiratory Mechanics; Sputum; Viscosity	2002

Article

Year

Deposition of nacystelyn from a dry powder inhaler in healthy volunteers and cystic fibrosis patients.

Drug development and industrial pharmacy, 2001, Volume: 27, Issue:3

Topics: Absorption; Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Analysis of Variance; Child; Cystic Fibrosis; Expectorants; Female; Humans; Lung; Lysine; Male; Powders; Radionuclide Imaging; Technetium; Tissue Distribution

2001

Dose-finding and 24-h monitoring for efficacy and safety of aerosolized Nacystelyn in cystic fibrosis.

The European respiratory journal, 2002, Volume: 19, Issue:2

Topics: Acetylcysteine; Administration, Inhalation; Adolescent; Adult; Aerosols; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Female; Humans; Lysine; Male; Nebulizers and Vaporizers; Respiratory Mechanics; Sputum; Viscosity

2002

Other Studies

19 other study(ies) available for lysine and Cystic Fibrosis

Article	Year
Opposite regulation of F508del-CFTR biogenesis by four poly-lysine ubiquitin chains In vitro. Biochimica et biophysica acta. Proteins and proteomics, 2022, 06-01, Volume: 1870, Issue:6 Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Lysine; Proteasome Endopeptidase Complex; Ubiquitin	2022
A treatment evaluator tool to monitor the real-world effectiveness of inhaled aztreonam lysine in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:6 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Aztreonam; Body Mass Index; Cystic Fibrosis; Drug Monitoring; Female; Forced Expiratory Volume; Hospitalization; Humans; Lysine; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Treatment Outcome	2017
Non-steroidal anti-inflammatory drug for pulmonary administration: design and investigation of ketoprofen lysinate fine dry powders. International journal of pharmaceutics, 2013, May-01, Volume: 448, Issue:1 Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cell Line; Cell Proliferation; Cystic Fibrosis; Drug Compounding; Drug Design; Dry Powder Inhalers; Humans; Ketoprofen; Leucine; Lysine; Microscopy, Electron, Scanning; Mucus; Particle Size; Powders	2013
Poly-L-Lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum. American journal of respiratory and critical care medicine, 2013, Sep-15, Volume: 188, Issue:6 Topics: Adult; Aged; Animals; Anti-Bacterial Agents; Cathepsin G; Cystic Fibrosis; Disease Models, Animal; DNA; Female; Flow Cytometry; Humans; Leukocyte Elastase; Lung; Lysine; Male; Mice; Middle Aged; Neutrophils; Peptide Hydrolases; Proteolysis; Pseudomonas aeruginosa; Sputum; Staphylococcus aureus	2013
Faster, higher, stronger. American journal of respiratory and critical care medicine, 2013, Sep-15, Volume: 188, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cystic Fibrosis; DNA; Female; Humans; Lysine; Male; Peptide Hydrolases; Sputum	2013
Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools. Molecular and cellular biology, 2014, Volume: 34, Issue:14 Topics: Cell Line; Cell Membrane; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; HEK293 Cells; Humans; Lysine; Mass Spectrometry; Models, Molecular; Mutation; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Protein Stability; Protein Structure, Tertiary; Protein Transport; Proteolysis; Ubiquitin; Ubiquitination	2014
Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate. Journal of aerosol medicine and pulmonary drug delivery, 2016, Volume: 29, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Cystic Fibrosis; Dry Powder Inhalers; Elastic Modulus; Female; Humans; Ketoprofen; Lysine; Male; Middle Aged; Models, Biological; Permeability; Rheology; Sodium Bicarbonate; Sputum; Viscosity; Young Adult	2016
Inhaled aztreonam. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:5 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Drug Discovery; Humans; Lysine; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome	2010
Aztreonam lysine for inhalation solution in cystic fibrosis: profile report. Paediatric drugs, 2011, Apr-01, Volume: 13, Issue:2 Topics: Administration, Inhalation; Adult; Aztreonam; Cystic Fibrosis; Humans; Infant; Lysine; Solutions; Young Adult	2011
Detection of the R553X DNA single point mutation related to cystic fibrosis by a "chiral box" D-lysine-peptide nucleic acid probe by capillary electrophoresis. Electrophoresis, 2005, Volume: 26, Issue:22 Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Probes; Electrophoresis, Capillary; Humans; Lysine; Nucleic Acid Hybridization; Peptide Nucleic Acids; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Stereoisomerism	2005
A new missense mutation (E92K) in the first transmembrane domain of the CFTR gene causes a benign cystic fibrosis phenotype. Human molecular genetics, 1993, Volume: 2, Issue:1 Topics: Base Sequence; Child; Codon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Genotype; Glutamates; Glutamic Acid; Humans; Lysine; Male; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenotype; Point Mutation; Polymerase Chain Reaction	1993
Mutation of R555 in CFTR-delta F508 enhances function and partially corrects defective processing. Receptors & channels, 1996, Volume: 4, Issue:1 Topics: Amino Acid Sequence; Arginine; ATP-Binding Cassette Transporters; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Fungal Proteins; Humans; Ion Channel Gating; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Suppression, Genetic; Yeasts	1996
Reduction in viscoelasticity in cystic fibrosis sputum in vitro using combined treatment with nacystelyn and rhDNase. Pediatric pulmonology, 1996, Volume: 22, Issue:3 Topics: Acetylcysteine; Adolescent; Adult; Cystic Fibrosis; Deoxyribonuclease I; Elasticity; Expectorants; Humans; In Vitro Techniques; Lysine; Recombinant Proteins; Rheology; Sputum; Viscosity	1996
Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium. Gene therapy, 2001, Volume: 8, Issue:18 Topics: Acetylcysteine; Animals; Chloramphenicol O-Acetyltransferase; Cholinergic Antagonists; Cystic Fibrosis; Dose-Response Relationship, Drug; Expectorants; Gene Expression; Genetic Therapy; Genetic Vectors; Glycopyrrolate; Injections, Intramuscular; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred CFTR; Models, Animal; Nasal Mucosa; Sheep; Trachea	2001
Intracellular rate-limiting steps of gene transfer using glycosylated polylysines in cystic fibrosis airway epithelial cells. Gene therapy, 2002, Volume: 9, Issue:15 Topics: Cystic Fibrosis; Epithelial Cells; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Lactose; Luciferases; Lysine; Mannose; Plasmids; Respiratory Mucosa; Second Messenger Systems; Transcription, Genetic; Tumor Cells, Cultured	2002
Small bowel mucosal dysfunction in patients with cystic fibrosis. The Journal of pediatrics, 1976, Volume: 88, Issue:2 Topics: Adolescent; Celiac Disease; Child; Child, Preschool; Cycloleucine; Cystic Fibrosis; Dipeptidases; Disaccharidases; Humans; Intestinal Mucosa; Intestine, Small; Lysine; Malabsorption Syndromes; Phenylalanine	1976
Detection of novel and rare mutations in exon 4 of the cystic fibrosis gene by SSCP. Human molecular genetics, 1992, Volume: 1, Issue:6 Topics: Amino Acid Sequence; Base Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA; DNA, Single-Stranded; Exons; Glutamine; Humans; Ion Channels; Lysine; Membrane Proteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic	1992
Studies on basic charged molecules and cell membranes in cystic fibrosis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:4 Topics: Albumins; Animals; Carbon Isotopes; Cell Membrane; Cells, Cultured; Cystic Fibrosis; Electrophoresis; Electrophoresis, Disc; Fibroblasts; gamma-Globulins; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Lysine; Mitochondria, Liver; Peptides; Rats; Saliva; Sarcoma 180; Serum Albumin, Radio-Iodinated; Succinates; Sulfur Isotopes; Thiamine	1971
Studies on the mechanism of inhibition of sodium transport in cystic fibrosis of the pancreas. Pediatric research, 1968, Volume: 2, Issue:5 Topics: Animals; Arginine; Biological Transport; Cell Membrane Permeability; Cystic Fibrosis; Heparin; Humans; Imines; Lysine; Macromolecular Substances; Male; Parotid Gland; Rats; Saliva; Sodium	1968