lysine has been researched along with Colorectal Neoplasms in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 20 (52.63) | 24.3611 |
| 2020's | 12 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, J; Cao, JM; Feng, YL; Gao, LJ; Hou, JY; Shen, J; Shi, JY; Wang, DP; Yan, Z; Zhang, FP; Zhou, L | 1 |
| Dammer, EB; Danelia, D; Duong, DM; Seyfried, NT; Yu, DS; Zhang, H | 1 |
| Huang, Z; Wang, H; Yang, M | 1 |
| Brezmes, J; Cumeras, R; Gumà, J; Llambrich, M | 1 |
| Cui, L; Fang, L; Guan, X; Liao, Y; Liu, C; Liu, R; Lu, X; Sun, H; Wang, B; Yao, Y; Zhang, D; Zhang, Y | 1 |
| Gu, Y; Ma, Q; Tao, Y; Zhang, Y | 1 |
| Ha, J; Jung, SM; Kim, M; Lee, J; Park, JS; Park, SH; Seo, D | 1 |
| Chen, W; Du, W; He, Y; Liu, N; Liu, X; Yang, Y; Zhang, Y | 1 |
| Liu, HY; Liu, MY; Sun, HL; Zhang, HS; Zhou, Z | 1 |
| Lei, H; Tao, K | 1 |
| Chen, S; Cheng, X; Fang, W; Hao, H; Hu, X; Hua, F; Huang, D; Huang, Z; Li, Q; Liu, F; Luo, Z; Xiao, F; Zhang, X | 1 |
| Agostinelli, E; Bertani, C; Bordone, R; Canettieri, G; Coni, S; De Smaele, E; Di Magno, L; Di Marcotullio, L; Fatica, A; Giannini, G; Guerrieri, F; Ianniello, Z; Infante, P; Licursi, V; Macone, A; Maroder, M; Moretti, M; Petroni, M; Serrao, SM; Yurtsever, ZN | 1 |
| Aglago, EK; Aleksandrova, K; Amiano, P; Bueno-de-Mesquita, B; Colorado-Yohar, SM; Dahm, CC; Fedirko, V; Freisling, H; Gram, IT; Gunter, MJ; Gurrea, AB; Heath, AK; Hughes, DJ; Jakszyn, P; Jenab, M; Jiao, L; Johnson, T; Katzke, V; Macciotta, A; Masala, G; Mayén, AL; Olsen, A; Perez-Cornago, A; Sánchez, MJ; Sandanger, T; Schalkwijk, CG; Schulze, MB; Sieri, S; Simeon, V; Skeie, G; Tjønneland, A; Tumino, R; Weiderpass, E | 1 |
| Chen, J; Chen, L; Fang, H; Fang, L; Ge, X; Han, D; Jiao, C; Jin, J; Jin, X; Li, C; Li, Y; Liao, G; Liao, L; Liu, M; Liu, Z; Peng, X; Qin, HL; Teng, H; Wang, P; Wang, X; Wang, Y; Wei, Q; Weng, L; Yang, Y; Zhang, S; Zhao, B; Zhou, D; Zhou, J | 1 |
| Antunes, L; Carvalho, S; Freitas, M; Henrique, R; Jerónimo, C; Monteiro-Reis, S; Paulino, S; Tavares, A; Videira, JF; Vieira-Coimbra, M | 1 |
| An, S; Huang, G; Jia, W; Liu, J; Shen, M; Shi, L; Yan, H; Zhang, R; Zhao, L | 1 |
| Bartels, CF; Bayles, I; Faber, ZJ; Hong, ES; Hung, S; Kalady, MF; Liu, R; Markowitz, S; Morton, AR; Neu, D; Ojo, E; Pontius, WD; Saiakhova, A; Scacheri, PC; Wald, DN | 1 |
| Braga, VNL; Cavalcanti, BC; Dornelas, CA; Jamacaru, FVF; Juanes, CC; Lemos, TLG; Peres Júnior, HS; Sousa, JR | 1 |
| Bai, JJ; Cao, J; Farooqi, AS; Hong, JY; Kosciuk, T; Lin, H; Lu, X; Price, IR; Yang, M; Zhao, Q | 1 |
| Andrade, N; Correia-Branco, A; Ferreira, AC; Martel, F; Silva, C; Soares, ML; Sonveaux, P; Stephenne, J | 1 |
| Cao, W; Chen, HY; Cui, Y; Du, W; Fang, JY; Han, ZG; Hong, J; Lin, YW; Ren, LL; Shen, N; Sun, DF; Sun, TT; Wang, JL; Wang, YC; Wang, ZH; Weng, YR; Xiong, H; Xu, J; Yu, YN; Zou, W | 1 |
| Akaike, M; Kameda, Y; Masuda, M; Miyagi, Y; Morinaga, S; Nakamura, Y; Numata, M; Oshima, T; Rino, Y; Sakuma, Y; Shiozawa, M; Tamagawa, H; Yamamoto, N; Yoshihara, M; Yukawa, N | 1 |
| Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y | 1 |
| Gao, C; Gao, W; Hu, Z; Li, Q; Ma, Z; Wei, D; Wu, Z; Xu, Y; Zhu, X | 1 |
| Jiang, K; Luo, J; Mustonen, H; Puolakkainen, P; Shen, Z; Wang, B; Wang, S; Ye, Y; Zhang, H; Zhu, J | 1 |
| Balaji, R; Balasubramanian, D; Bartels, CF; Crawford, GE; Laframboise, T; Scacheri, PC; Schnetz, MP; Shastri, K; Song, L; Wang, Z; Zentner, GE; Zhang, X | 1 |
| Chan, AT | 1 |
| Engin, A; Engin, AB; Karahalil, B; Karakaya, AE | 1 |
| Andrews, R; Bird, AP; Gruenewald-Schneider, U; Harrison, DJ; Illingworth, RS; James, KD; Kerr, AR; Smith, C; Turner, DJ; Webb, S | 1 |
| Choi, BH; Choi, EK; Jeong, SY; Oh, ET; Park, HJ; Park, MT; Ro, S | 1 |
| Benamouzig, R; Chaussade, S; Deyra, J; Girard, B; Little, J; Martin, A; Uzzan, B | 1 |
| Akaike, M; Imada, T; Kameda, Y; Masuda, M; Miyagi, Y; Morinaga, S; Nakamura, Y; Oshima, T; Sakuma, Y; Shiozawa, M; Tamagawa, H; Yoshihara, M | 1 |
| Fukami, K; Honda, K; Jigami, T; Kitabayashi, I; Satow, R; Shitashige, M; Yamada, T | 1 |
| Issa, JP; Kondo, Y; Shen, L | 1 |
| Akino, K; Endo, T; Fujita, M; Hinoda, Y; Hosokawa, M; Ikeda, H; Imai, K; Kanaseki, T; Mita, H; Morimoto, Y; Sasaki, Y; Sato, N; Satoh, A; Soejima, H; Suzuki, H; Takamura, Y; Tokino, T; Toyota, M; Urano, T; Yanagihara, K | 1 |
| Bonanno, E; Calvani, M; Mazzarelli, P; Pucci, S; Sesti, F; Spagnoli, LG | 1 |
| Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ | 1 |
| Hajer, J; Kepelová, A; Kment, M; Zádorová, Z | 1 |
1 review(s) available for lysine and Colorectal Neoplasms
| Article | Year |
|---|---|
Urine NMR Metabolomics for Precision Oncology in Colorectal Cancer.
Topics: Acetates; Acetone; Biomarkers; Carnitine; Colorectal Neoplasms; Creatinine; Glucose; Humans; Lysine; Metabolomics; Precision Medicine; Prospective Studies; Pyruvic Acid; Threonine; Urea | 2022 |
1 trial(s) available for lysine and Colorectal Neoplasms
| Article | Year |
|---|---|
Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial.
Topics: Adenoma; Adenomatous Polyps; Aged; Aspirin; Colonoscopy; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Secondary Prevention; Treatment Outcome | 2012 |
36 other study(ies) available for lysine and Colorectal Neoplasms
| Article | Year |
|---|---|
Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; CREB-Binding Protein; DNA-Binding Proteins; Humans; Lysine; Mass Spectrometry; Neoplasm Metastasis; Phosphopyruvate Hydratase; Protein Processing, Post-Translational; Sirtuin 2; Tumor Suppressor Proteins; Up-Regulation | 2021 |
Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates.
Topics: Acetylation; Colorectal Neoplasms; Humans; Lysine; Proteins; Proteomics; Sirtuin 2 | 2022 |
Long non-coding RNA tumor protein 73 antisense RNA 1 influences an interaction between lysine demethylase 5A and promoter of tumor protein 73 to enhance the malignancy of colorectal cancer.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Lysine; MicroRNAs; Neoplasm Proteins; Retinoblastoma-Binding Protein 2; RNA, Antisense; RNA, Long Noncoding; Tumor Protein p73 | 2022 |
ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization.
Topics: Activin Receptors, Type II; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Humans; Lysine; MicroRNAs; Tyrosine Kinase Inhibitors; Ubiquitin-Specific Proteases | 2023 |
Butyrate facilitates immune clearance of colorectal cancer cells by suppressing STAT1-mediated PD-L1 expression.
Topics: B7-H1 Antigen; Butyrates; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colorectal Neoplasms; Humans; Lysine; STAT1 Transcription Factor | 2023 |
The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway.
Topics: Activin Receptors, Type I; ATP-Binding Cassette Transporters; Bone Morphogenetic Protein 6; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Humans; Lysine; Models, Biological; Neoplastic Stem Cells; Polyubiquitin; Prognosis; Proteasome Endopeptidase Complex; Protein Binding; Protein Stability; Signal Transduction; Trans-Activators; Ubiquitin-Protein Ligases; Ubiquitination | 2019 |
PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2.
Topics: Aerobiosis; Aged; Caco-2 Cells; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Colorectal Neoplasms; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Hexokinase; HT29 Cells; Humans; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Up-Regulation | 2020 |
TSPAN8 promotes colorectal cancer cell growth and migration in LSD1-dependent manner.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Tetraspanins | 2020 |
Somatic mutations in colorectal cancer are associated with the epigenetic modifications.
Topics: Base Pairing; Base Sequence; Binding Sites; CCCTC-Binding Factor; Chromatin; Colorectal Neoplasms; CpG Islands; DNA Methylation; Enhancer Elements, Genetic; Epigenesis, Genetic; Genome, Human; HCT116 Cells; Histones; Humans; Lysine; Methylation; MicroRNAs; Mutation | 2020 |
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Topics: Animals; Carcinogenesis; CDX2 Transcription Factor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multivariate Analysis; Nuclear Proteins; Promoter Regions, Genetic; Repressor Proteins; Survival Analysis; Up-Regulation; Wnt Signaling Pathway | 2020 |
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Topics: Adenomatous Polyposis Coli; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Eukaryotic Translation Initiation Factor 5A; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Nude; Open Reading Frames; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Peptides; Polyamines; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins | 2020 |
Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study.
Topics: Adult; Aged; Chromatography, Liquid; Cohort Studies; Colorectal Neoplasms; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Odds Ratio; Ornithine; Tandem Mass Spectrometry | 2021 |
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Topics: A549 Cells; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; Methylation; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Prognosis; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Signal Transduction; Transcription Factors; Tumor Burden; YAP-Signaling Proteins | 2018 |
Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancer.
Topics: Aged; Biomarkers, Tumor; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Female; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lysine; Male; Methylation; Middle Aged; Prognosis; Protein Methyltransferases; Retrospective Studies | 2018 |
SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer.
Topics: Acetylation; Amino Acid Sequence; Animals; Autophagy; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Colorectal Neoplasms; Female; HEK293 Cells; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lysine; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Prognosis; Protein Binding; Sirtuins | 2019 |
Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes.
Topics: Acetylation; Animals; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; DNA Mismatch Repair; Enhancer Elements, Genetic; Epigenome; Gene Expression Regulation; Histones; Humans; INDEL Mutation; Lysine; Mice; Microsatellite Instability; Mutation; Nucleotide Motifs; Phenotype; Selection, Genetic; Transcription Factors | 2019 |
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane1.
Topics: Animals; Azoxymethane; Carcinogens; Colorectal Neoplasms; Disease Models, Animal; Gum Arabic; Lysine; Male; Oxidative Stress; Precancerous Conditions; Propolis; Rats; Rats, Wistar | 2019 |
Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Lysine; Male; Mice; Mice, Transgenic; Molecular Docking Simulation; Protein Isoforms; Sirtuin 2; Structure-Activity Relationship; Thiourea | 2019 |
Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Glucose; Humans; Lactic Acid; Lysine; Pancreatic Neoplasms; Polyphenols | 2019 |
Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer.
Topics: Animals; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Polycomb Repressive Complex 2; Receptors, Calcitriol; Recombinant Fusion Proteins; RNA Interference; Signal Transduction; STAT3 Transcription Factor | 2013 |
Global histone modification of H3K27 correlates with the outcomes in patients with metachronous liver metastasis of colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Polycomb Repressive Complex 2; Prognosis; Retrospective Studies; Risk Factors; Tissue Array Analysis | 2013 |
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.
Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation | 2013 |
TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells.
Topics: Acetyl Coenzyme A; Acetylation; Animals; Cell Line, Tumor; Cellular Reprogramming; Colorectal Neoplasms; E1A-Associated p300 Protein; Fatty Acids; Genes, myc; Heterografts; Humans; Liver Neoplasms; Low Density Lipoprotein Receptor-Related Protein-6; Lysine; Mice; Mice, Knockout; Neoplastic Stem Cells; Oxidative Stress; Receptors, Thrombopoietin; Thrombopoietin | 2015 |
Global-scale profiling of differential expressed lysine acetylated proteins in colorectal cancer tumors and paired liver metastases.
Topics: Acetylation; Binding Sites; Biopsy; Colorectal Neoplasms; Gene Expression Regulation; Humans; Liver Neoplasms; Lysine; Metabolic Networks and Pathways; Neoplasm Metastasis; Neoplasm Proteins; Protein Interaction Maps; Protein Processing, Post-Translational; Proteome | 2016 |
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chromatin; Chromatin Immunoprecipitation; Colorectal Neoplasms; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Enhancer Elements, Genetic; Histones; Humans; Luciferases; Lysine; Mice; Neuroblastoma; Neurons; Oligonucleotide Array Sequence Analysis; Transcription Initiation Site; Transcription, Genetic | 2009 |
COX-2 expression in adenoma: an imperfect marker for chemoprevention.
Topics: Adenoma; Anticarcinogenic Agents; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Lysine; Neoplasm Recurrence, Local | 2010 |
Oxidative stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln polymorphisms in a Turkish population with colorectal carcinoma.
Topics: Adult; Aged; Amino Acid Substitution; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA-Binding Proteins; Genetics, Population; Glutamine; Helicobacter Infections; Helicobacter pylori; Humans; Lysine; Middle Aged; Mutation, Missense; Oxidative Stress; Polymorphism, Single Nucleotide; Serine; Turkey; Xeroderma Pigmentosum Group D Protein | 2010 |
Orphan CpG islands identify numerous conserved promoters in the mammalian genome.
Topics: Adult; Animals; Base Sequence; Chromatography, Affinity; Colorectal Neoplasms; Conserved Sequence; CpG Islands; DNA Methylation; Female; Genome; Histones; Humans; Lysine; Male; Mammals; Mice; Middle Aged; Organ Specificity; Promoter Regions, Genetic; Sequence Analysis, DNA; Transcription, Genetic; Young Adult | 2010 |
Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells.
Topics: Acetylation; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Lysine; Male; Mutation; Naphthalenes; Prostatic Neoplasms; Protein Stability; Proto-Oncogene Proteins c-mdm2; Time Factors; Transcriptional Activation; Transfection; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2012 |
The global histone modification pattern correlates with overall survival in metachronous liver metastasis of colorectal cancer.
Topics: Acetylation; Colorectal Neoplasms; Female; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Neoplasms, Second Primary; Prognosis; Protein Processing, Post-Translational; Retrospective Studies; Survival Rate | 2012 |
β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cell Nucleus; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Humans; Lysine; Molecular Chaperones; Nuclear Pore Complex Proteins; Nuclear Proteins; Promyelocytic Leukemia Protein; Protein Binding; Protein Isoforms; RNA Interference; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcription Factor 4; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2012 |
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carrier Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Methylation; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured | 2003 |
Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.
Topics: Blotting, Western; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Chromatin Immunoprecipitation; Colorectal Neoplasms; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; DNA, Complementary; Flow Cytometry; Gene Silencing; Histones; HLA-DR Antigens; Humans; Immunohistochemistry; Interferon-gamma; Lysine; Models, Genetic; Nuclear Proteins; Plasmids; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Signal Transduction; STAT1 Transcription Factor; Stomach Neoplasms; Sulfites; Trans-Activators; Transcription, Genetic; Transfection | 2004 |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?
Topics: Acetylation; Adenocarcinoma; Aged; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Nucleus; Chromatin Immunoprecipitation; Colorectal Neoplasms; Fatty Acid Synthases; Female; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Lysine; Male; Transcription, Genetic | 2007 |
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms | 2008 |
Two novel germline mutations (Y548X and K732X) of the MLH1 gene in Czech patients with hereditary nonpolyposis colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Adult; Base Pair Mismatch; Carrier Proteins; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Female; Germ-Line Mutation; Humans; Lysine; Male; Molecular Sequence Data; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Polymorphism, Genetic; Tyrosine | 2000 |