Page last updated: 2024-08-17

lysine and Colonic Neoplasms

lysine has been researched along with Colonic Neoplasms in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.64)	18.7374
1990's	8 (13.11)	18.2507
2000's	19 (31.15)	29.6817
2010's	24 (39.34)	24.3611
2020's	9 (14.75)	2.80

Authors

Authors	Studies
Allu, PK; Black, BE; Dawicki-McKenna, JM; Fachinetti, D; Gambogi, CW; Logsdon, GA; Salinas-Luypaert, C	1
Hahm, JY; Hong, YJ; Kim, SH; Lee, DH; Park, J; Park, KS; Seo, SB	1
Chakraborty, S; Mishra, J; Patra, SK; Roy, A; Singh, SP	1
Qi, Y; Zhao, Y	1
Alnajjar, KS; Goodman, MF; Haratipour, P; Huang, J; Kashemirov, BA; Krylov, IS; Mahmoud, M; McKenna, CE; Negahbani, A; Sweasy, JB	1
Choi, YS; Jeong, JH; Kim, YJ; Kwon, SH; Lee, DH	1
Bruer, M; Reinhardt, D; Thakur, BK; Welte, K	1
Barlev, N; Daks, A; Fedorova, O; Nader, R; Petukhov, A; Shuvalov, O; Vasileva, E	1
Benelli, D; Catalanotto, C; La Teana, A; Londei, P; Martella, M; Talora, C	1
Jang, MM; Jin, GR; Ju, BG; Jung, TY; Kim, CW; Kim, H; Kim, HS; Koo, YB; Lee, CY; Lee, SY	1
Byun, Y; Chang, KY; Choi, JU; Jha, SK; Kang, SH; Kweon, S; Pangeni, R; Park, JW; Subedi, L	1
Song, J; Wan, J; Wang, P; Wang, T; Wang, Y; Xu, W; Zhan, J; Zhang, H	1
Chen, S; Liu, B; Liu, M; Luo, J; Qi, H; Shi, X; Song, S; Yu, M; Zhu, WG; Zou, J	1
Chen, C; Chen, YM; Li, Y; Lin, Y; Mei, XY; Qu, YY; Wang, D; Xu, W; Yang, SB; Zhang, X; Zhao, JY; Zhao, R; Zhao, SM; Zhou, Q; Zuo, ZG	1
Liu, TT; Liu, XN; Liu, XS; Ouyang, SW; Peng, ZH; Zhu, FM; Zhu, FX	1
Chen, H; Cheng, Q; Huang, R; Li, S; Qian, Y; Shao, Z; Wang, H; Xiang, M; Xie, R; Xu, N; Xu, Q; Zhou, Z	1
Jia, L; Liu, J; Wan, L; Xu, H; Xu, J; Zheng, N	1
Chang, CK; Chen, CL; Chen, SH; Chou, YA; Dong, JJ; Hsiao, M; Huang, MS; Jan, YH; Lai, TC; Liang, PH; Lin, YF; Liu, HG; Teng, KH; Tian, WT; Yang, CJ	1
Barknowitz, G; Brigelius-Flohé, R; Florian, S; Glatt, H; Haack, M; Kipp, AP; Lehmann, C; Lippmann, D; Mewis, I; Schreiner, M; Wiesner, M	1
Ai, G; Alfonso, LF; Bhat, GJ; Dachineni, R; Kumar, DR; Marimuthu, S	1
Jia, YL; Li, YC; Sun, QL; Wang, L; Wang, TY; Wang, XY; Zhang, JH; Zhang, X; Zhao, CP	1
Akiyama, T; Hiyoshi, M; Iwasaki, K; Kawasaki, Y; Kitayama, J; Kozuka-Hata, H; Kurimoto, A; Nagashima, T; Nasu, E; Negishi, L; Okada-Hatakeyama, M; Oyama, M; Sugimasa, H; Takeda, Y; Taniue, K	1
Guo, Y; Huang, MT; Kong, AN; Li, W; Liu, Y; Su, ZY; Zhang, C	1
Chang, WY; Hyun, JW; Kang, HK; Kang, KA; Keum, YS; Piao, MJ; Ryu, YS	1
Chai, YR; Gao, JH; Han, HF; Jia, YL; Peng, XJ; Wang, TY	1
Han, F; Han, L; Huang, CY; Jin, G; Li, CF; Lin, HK; Liu, C; Rezaeian, AH; Tsai, CH; Tsai, FJ; Watabe, K; Wu, CY; Xu, C; Xu, X; Zhang, L; Zhang, X	1
Hou, L; Hu, B; Meng, X; Sun, J; Wang, J; Zhao, H; Zhu, D	1
Ge, X; Jin, Q; Yan, T; Zhai, Q; Zhang, F	1
Fujisaki, Y; Horii, Y; Nagai, K; Shen, J	1
Andersson, R; Enroth, S; Komorowski, J; Påhlman, L; Rada-Iglesias, A; Wadelius, C; Wanders, A	1
Aranganathan, S; Gopalan, R; Nalini, N; Selvam, JP	1
Becker, K; Hanel, W; Li, D; Marchenko, ND; Moll, UM; Reich, N	1
Kawano, K; Maitani, Y; Shiraishi, K; Yokoyama, M	1
Accardo, A; Bracci, L; Brunetti, J; Falciani, C; Lelli, B; Morelli, G; Pini, A; Tesauro, D	1
Bartels, SJ; Bock, C; Brinkman, AB; Gnirke, A; Gu, H; Marks, H; Matarese, F; Meissner, A; Simmer, F; Stunnenberg, HG; Zhang, Y	1
Casero, RA; Hanigan, CL; Jin, L; Park, BH; Wang, W; Woster, PM; Wu, Y	1
Charbonnière, LJ; Christine, C; Clavier, S; Ehret-Sabatier, L; Koubemba, M; Orend, G; Saupe, F; Shakir, S	1
Bartley, SM; Farnham, PJ; Green, R; Kirmizis, A; Kuzmichev, A; Margueron, R; Reinberg, D	1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW	1
Bar Meir, S; Fidder, HH; Figer, A; Friedman, E; Zidan, J	1
Ben-Shushan, E; Bergman, Y; Cedar, H; Eden, E; Farkash, S; Hecht, M; Keshet, I; Reubinoff, BE; Schlesinger, Y; Simon, I; Straussman, R; Yakhini, Z; Zimmerman, J	1
Alimonti, A; Carver, BS; Chen, Z; Chi, SG; Cordon-Cardo, C; Erdjument-Bromage, H; Jiang, X; Kim, HJ; Misteli, T; Pandolfi, PP; Pavletich, NP; Tempst, P; Teruya-Feldstein, J; Trotman, LC; Wang, X; Yang, H	1
Fujita, T; Furumai, T; Igarashi, Y; Miyanaga, S; Obata, T; Onaka, H; Saiki, I; Saito, N; Sakurai, H	1
Bernard, BF; Breeman, WA; de Jong, M; de Visser, M; Erion, JL; Janssen, PJ; Krenning, EP; Srinivasan, A; Verwijnen, SM; Vulto, AG	1
Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R	1
Aranganathan, S; Nalini, N; Panneer Selvam, J	1
Goto, M; Hamada, T; Higashi, M; Nishida, Y; Nomoto, M; Tsutsumida, H; Yamada, N; Yonezawa, S	1
Bajbouj, K; Habold, C; Hartig, R; Korkmaz, KS; Poehlmann, A; Roessner, A; Schneider-Stock, R	1
Buchner, J; Haslbeck, M; Schmid, K; Somoza, V	1
Di Girolamo, M; Ferruzza, S; Ranaldi, G; Sambuy, Y	1
Bair, HJ; Becker, WS; Behr, TM; Blumenthal, RD; Dunn, RM; Goldenberg, DM; Griffiths, GL; Juweid, ME; Sharkey, RM; Wolf, FG	1
Hanson, LA; Lomonte, B; Tarkowski, A	1
Alvarez-Diez, TM; Polihronis, J; Reilly, RM	1
Grossie, VB; Nishioka, K	1
Adelstein, SJ; Harapanhalli, RS; Jones, PL; Kassis, AI; Mahmood, A; Matalka, KZ	1
de los Santos, AR; Di Girolamo, G; Franchi, A; Gimeno, MA; Marti, ML	1
Arano, Y; Konishi, J; Nakamoto, Y; Ono, M; Saga, T; Saji, H; Sakahara, H; Sato, N; Yao, Z; Zhang, M; Zhao, S	1
Shimizu, K; Shimizu, N; Soga, H; Tanino, M; Tsukuda, K	1
Erbersdobler, HF; Faist, V; Fölsch, UR; Günther, R; Zill, H	1
De Los Santos, AR; Di Girolamo, G; Farina, M; Fernández de Gimeno, MA; Franchi, A; Martí, ML	1
Anderson, RL; Hahn, GM; Kapp, DS; Lee, KJ; Rice, GC; Woo, SY	1

Trials

1 trial(s) available for lysine and Colonic Neoplasms

Article	Year
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8 Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine	2007

Article

Year

Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8

Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine

2007

Other Studies

60 other study(ies) available for lysine and Colonic Neoplasms

Article	Year
Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A Cell reports, 2021, 11-02, Volume: 37, Issue:5 Topics: Cell Line, Tumor; Cell Survival; Centromere; Centromere Protein A; Chromatin; Chromatin Assembly and Disassembly; Colonic Neoplasms; Gene Editing; Genetic Techniques; Humans; Lysine; Mutation; Retinal Pigment Epithelium; Ubiquitination	2021
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation. Genes & genomics, 2022, Volume: 44, Issue:11 Topics: Acetylation; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Colonic Neoplasms; DNA Methylation; Humans; Lysine; Lysine Acetyltransferase 5; RNA, Small Interfering; Ubiquitin-Protein Ligases; Ubiquitins	2022
Mechanistic aspects of reversible methylation modifications of arginine and lysine of nuclear histones and their roles in human colon cancer. Progress in molecular biology and translational science, 2023, Volume: 197 Topics: Arginine; Colonic Neoplasms; DNA Methylation; Histones; Humans; Lysine; Protein Processing, Post-Translational	2023
CBP-triggered KDM2B acetylation accelerates the carcinogenesis of colon cancer. Journal of cellular physiology, 2020, Volume: 235, Issue:3 Topics: Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; CREB-Binding Protein; F-Box Proteins; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Protein Processing, Post-Translational	2020
A pre-catalytic non-covalent step governs DNA polymerase β fidelity. Nucleic acids research, 2019, 12-16, Volume: 47, Issue:22 Topics: Adenomatous Polyposis Coli; Amino Acid Substitution; Base Sequence; Catalysis; Colonic Neoplasms; DNA Polymerase beta; DNA Replication; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Substrate Specificity; Templates, Genetic	2019
Benzo[ International journal of molecular sciences, 2019, Nov-25, Volume: 20, Issue:23 Topics: Carbamates; Cell Proliferation; Colonic Neoplasms; Enzyme Inhibitors; HeLa Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Tumor Cells, Cultured	2019
Insights into the limitations of transient expression systems for the functional study of p53 acetylation site and oncogenic mutants. Biochemical and biophysical research communications, 2020, 04-16, Volume: 524, Issue:4 Topics: Acetylation; Colonic Neoplasms; HCT116 Cells; Humans; Lysine; Mutagenesis; Mutation; Transcriptional Activation; Tumor Suppressor Protein p53	2020
KMT Set7/9 is a new regulator of Sam68 STAR-protein. Biochemical and biophysical research communications, 2020, 05-14, Volume: 525, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Colonic Neoplasms; Computational Biology; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Histone-Lysine N-Methyltransferase; Humans; Lysine; Mass Spectrometry; Methylation; Protein Binding; Protein Domains; Protein Interaction Maps; RNA-Binding Proteins	2020
Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes. International journal of molecular sciences, 2020, Jun-27, Volume: 21, Issue:13 Topics: Apoptosis; Cell Proliferation; Colonic Neoplasms; Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation, Neoplastic; Humans; Lysine; Peptide Initiation Factors; Protein Biosynthesis; Protein Processing, Post-Translational; Ribosomes; RNA-Binding Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2020
Deacetylation by SIRT1 promotes the tumor-suppressive activity of HINT1 by enhancing its binding capacity for β-catenin or MITF in colon cancer and melanoma cells. Experimental & molecular medicine, 2020, Volume: 52, Issue:7 Topics: Acetylation; Animals; beta Catenin; Cell Line, Tumor; Colonic Neoplasms; HEK293 Cells; Humans; Lysine; Male; Melanoma; Mice, Inbred BALB C; Mice, Nude; Microphthalmia-Associated Transcription Factor; Mutation; Nerve Tissue Proteins; Peptide Fragments; Protein Binding; Sialoglycoproteins; Sirtuin 1; Transcription, Genetic; Xenograft Model Antitumor Assays	2020
Improvements in the Oral Absorption and Anticancer Efficacy of an Oxaliplatin-Loaded Solid Formulation: Pharmacokinetic Properties in Rats and Nonhuman Primates and the Effects of Oral Metronomic Dosing on Colorectal Cancer. International journal of nanomedicine, 2020, Volume: 15 Topics: Administration, Metronomic; Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chenodeoxycholic Acid; Colonic Neoplasms; Drug Carriers; Female; Glycerides; Humans; Intestinal Absorption; Lysine; Macaca fascicularis; Male; Mice, Inbred BALB C; Oxaliplatin; Poloxamer; Rats, Sprague-Dawley	2020
HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression. Cancer letters, 2018, 07-10, Volume: 426 Topics: Acetylation; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Disease Progression; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HeLa Cells; Homeodomain Proteins; Humans; Lysine; Male; MCF-7 Cells; Prognosis; Survival Analysis	2018
Sirtuin 7-mediated deacetylation of WD repeat domain 77 (WDR77) suppresses cancer cell growth by reducing WDR77/PRMT5 transmethylase complex activity. The Journal of biological chemistry, 2018, 11-16, Volume: 293, Issue:46 Topics: Acetylation; Cell Proliferation; Colonic Neoplasms; CREB-Binding Protein; HCT116 Cells; HEK293 Cells; Humans; Lysine; Protein Multimerization; Protein-Arginine N-Methyltransferases; Sirtuins; Transcription Factors	2018
Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair. Cell reports, 2018, 10-09, Volume: 25, Issue:2 Topics: Animals; Apoptosis; Case-Control Studies; Cell Proliferation; Colonic Neoplasms; Diet, High-Fat; DNA Damage; DNA Repair; Homocysteine; Humans; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Protein Processing, Post-Translational; Rats; Rats, Wistar; Rectal Neoplasms; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2018
USP10 regulates Musashi-2 stability via deubiquitination and promotes tumour proliferation in colon cancer. FEBS letters, 2019, Volume: 593, Issue:4 Topics: Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Lysine; Protein Stability; RNA-Binding Proteins; Ubiquitin Thiolesterase; Ubiquitination; Up-Regulation	2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer. Molecular oncology, 2019, Volume: 13, Issue:4 Topics: Adenocarcinoma; Adenosine; Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Conditioned; Dendritic Cells; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Pancreatic Neoplasms; Phenylurea Compounds; Signal Transduction; Thiostrepton; Wnt-5a Protein	2019
HAMPT, A Novel Quadruple Drug Combination Designed for Cancer Metastatic Chemoprevention: From Hypothesis to Proof-of-concept. Current cancer drug targets, 2019, Volume: 19, Issue:4 Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Doxycycline; Drug Therapy, Combination; Female; Hormone Antagonists; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Mifepristone; Proof of Concept Study; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2019
Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies. The Journal of clinical investigation, 2013, Volume: 123, Issue:9 Topics: Alkylation; Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 7; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Activation; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lysine; MCF-7 Cells; Mice; Mice, Inbred NOD; Mice, SCID; Protein Interaction Maps; Signal Transduction; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays	2013
Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently. Food & function, 2014, Volume: 5, Issue:6 Topics: Animals; Anticarcinogenic Agents; Basic Helix-Loop-Helix Transcription Factors; Brassica; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Diet; Glucosinolates; Glutathione Peroxidase; Glutathione Transferase; Imidoesters; Indoles; Inflammation; Isothiocyanates; Lysine; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidoreductases Acting on Sulfur Group Donors; Oximes; Plant Extracts; Receptors, Aryl Hydrocarbon; Sulfoxides; Vegetables	2014
Aspirin acetylates wild type and mutant p53 in colon cancer cells: identification of aspirin acetylated sites on recombinant p53. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:5 Topics: Acetylation; Aspirin; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; HCT116 Cells; HT29 Cells; Humans; Lysine; Mutant Proteins; Protein Processing, Post-Translational; Protein Transport; Recombinant Proteins; Tumor Suppressor Protein p53	2016
Treating Colon Cancer Cells with FK228 Reveals a Link between Histone Lysine Acetylation and Extensive Changes in the Cellular Proteome. Scientific reports, 2015, Dec-17, Volume: 5 Topics: Acetylation; Antibiotics, Antineoplastic; Blotting, Western; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; Colonic Neoplasms; Depsipeptides; Dose-Response Relationship, Drug; Histones; Humans; Isotope Labeling; Lysine; Protein Processing, Post-Translational; Proteome; Proteomics; Tandem Mass Spectrometry	2015
Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proceedings of the National Academy of Sciences of the United States of America, 2016, Feb-02, Volume: 113, Issue:5 Topics: CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Colonic Neoplasms; Epigenesis, Genetic; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Nerve Tissue Proteins; Proteolysis; RNA, Long Noncoding; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation	2016
The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice. Carcinogenesis, 2016, Volume: 37, Issue:6 Topics: Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Epigenesis, Genetic; Histone Deacetylases; Histones; Lysine; Male; Mice, Inbred Strains; Neoplasms, Experimental; Nitric Oxide Synthase Type II	2016
Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells. Oncotarget, 2016, Jun-28, Volume: 7, Issue:26 Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydrogen Peroxide; Lysine; Mixed Function Oxygenases; Myeloid-Lymphoid Leukemia Protein; N-Acetylglucosaminyltransferases; NF-E2-Related Factor 2; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reactive Oxygen Species; RNA, Small Interfering; Up-Regulation	2016
Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells. Oncotarget, 2016, Aug-16, Volume: 7, Issue:33 Topics: Acetylation; Antibiotics, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; Depsipeptides; Histone Deacetylase Inhibitors; Humans; Lysine; Phosphorylation; Proteome; Receptor Cross-Talk	2016
TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression. Molecular cell, 2016, 11-17, Volume: 64, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytosol; E1A-Associated p300 Protein; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation; Protein Transport; Signal Transduction; Sulfonamides; Survival Analysis; TNF Receptor-Associated Factor 6; Tumor Suppressor Protein p53; Ubiquitination; Xenograft Model Antitumor Assays	2016
Crosstalk among proteome, acetylome and succinylome in colon cancer HCT116 cell treated with sodium dichloroacetate. Scientific reports, 2016, 11-22, Volume: 6 Topics: Acetylation; Amino Acid Sequence; Citric Acid Cycle; Cluster Analysis; Colonic Neoplasms; Dichloroacetic Acid; HCT116 Cells; Humans; Lysine; Neoplasm Proteins; Protein Processing, Post-Translational; Proteome; Succinates; Tandem Mass Spectrometry	2016
PCAF acetylates {beta}-catenin and improves its stability. Molecular biology of the cell, 2009, Volume: 20, Issue:1 Topics: Acetylation; Animals; beta Catenin; Cell Differentiation; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Humans; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; p300-CBP Transcription Factors; Protein Stability; Signal Transduction; Transcriptional Activation; Wnt Proteins	2009
Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation. Autonomic neuroscience : basic & clinical, 2009, May-11, Volume: 147, Issue:1-2 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arginine; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Immune Tolerance; Immunologic Factors; Killer Cells, Natural; Lysine; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neuroimmunomodulation; Rats; Rats, Wistar; Spleen; Sympathetic Nervous System; Treatment Outcome	2009
Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation. Epigenetics, 2009, Feb-16, Volume: 4, Issue:2 Topics: Adult; Colon; Colonic Neoplasms; DNA Methylation; Embryonic Stem Cells; Histones; Humans; Lysine; Methylation; Polycomb-Group Proteins; Repressor Proteins	2009
Chemopreventive efficacy of pronyl-lysine on lipid peroxidation and antioxidant status in rat colon carcinogenesis. Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:3 Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Cecum; Colon; Colonic Neoplasms; Lipid Peroxidation; Lysine; Male; Pyrroles; Rats; Rats, Wistar	2009
Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 binding. Cell death and differentiation, 2010, Volume: 17, Issue:2 Topics: Active Transport, Cell Nucleus; Adenocarcinoma; alpha Karyopherins; Cell Division; Cell Nucleus; Colonic Neoplasms; Cytoplasm; HCT116 Cells; Humans; Lung Neoplasms; Lysine; Protein Binding; Proto-Oncogene Proteins c-mdm2; Stress, Physiological; Tumor Suppressor Protein p53; Ubiquitination	2010
Polyion complex micelle MRI contrast agents from poly(ethylene glycol)-b-poly(l-lysine) block copolymers having Gd-DOTA; preparations and their control of T(1)-relaxivities and blood circulation characteristics. Journal of controlled release : official journal of the Controlled Release Society, 2010, Dec-01, Volume: 148, Issue:2 Topics: Animals; Colonic Neoplasms; Contrast Media; Dextran Sulfate; Female; Heterocyclic Compounds; Injections, Intravenous; Lysine; Magnetic Resonance Imaging; Mice; Micelles; Molecular Weight; Organometallic Compounds; Phantoms, Imaging; Polyamines; Polyelectrolytes; Polyethylene Glycols; Polymers; Tissue Distribution	2010
Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides. ChemMedChem, 2011, Apr-04, Volume: 6, Issue:4 Topics: 1,2-Dipalmitoylphosphatidylcholine; Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Drug Delivery Systems; Humans; Hydrodynamics; Liposomes; Lysine; Neurotensin; Peptide Fragments; Rhabdomyosarcoma; Tumor Cells, Cultured	2011
Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome research, 2012, Volume: 22, Issue:6 Topics: Animals; Cell Line; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Colonic Neoplasms; CpG Islands; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Gene Knockout Techniques; Genomics; Histones; Humans; Lysine; Mice; Sequence Analysis, DNA; Sulfites	2012
Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner. The Biochemical journal, 2013, Jan-15, Volume: 449, Issue:2 Topics: Animals; Blotting, Western; Cell Proliferation; Cluster Analysis; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; HCT116 Cells; Histone Demethylases; Histones; Humans; Lysine; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Transplantation, Heterologous; Tumor Suppressor Protein p53	2013
Synthesis of an activated phosphonated bifunctional chelate with potential for PET imaging and radiotherapy. Organic & biomolecular chemistry, 2012, Dec-14, Volume: 10, Issue:46 Topics: Antibodies, Monoclonal; Biopsy; Chelating Agents; Colonic Neoplasms; Cysteine; Ethylamines; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Multimodal Imaging; Neoplasm Proteins; Organophosphonates; Peptides; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Tenascin; Tomography, X-Ray Computed	2012
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes & development, 2004, Jul-01, Volume: 18, Issue:13 Topics: Carrier Proteins; Colonic Neoplasms; CpG Islands; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Macromolecular Substances; Methylation; Neoplasm Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Promoter Regions, Genetic; Proteins; Repressor Proteins; Transcription Factors	2004
In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry. Oncology reports, 2005, Volume: 13, Issue:3 Topics: Animals; Antioxidants; Ascorbic Acid; Colonic Neoplasms; Diet; Disease Progression; Immunohistochemistry; Ki-67 Antigen; Lysine; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Mucins; Neoplasms, Experimental; Proline; Tea; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2005
Colonic adenomas do not cosegregate with the I1307K APC missense mutation in an Israeli non-Ashkenazi family. Digestive diseases and sciences, 2005, Volume: 50, Issue:1 Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Chromosome Segregation; Colonic Neoplasms; Female; Genes, APC; Genetic Predisposition to Disease; Humans; Isoleucine; Israel; Jews; Lysine; Male; Middle Aged; Mutation, Missense; Pedigree	2005
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nature genetics, 2007, Volume: 39, Issue:2 Topics: Caco-2 Cells; Carrier Proteins; Cells, Cultured; Colonic Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms; Viral Envelope Proteins	2007
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell, 2007, Jan-12, Volume: 128, Issue:1 Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Cell Nucleus; Colonic Neoplasms; Endosomal Sorting Complexes Required for Transport; Glutamine; Hamartoma Syndrome, Multiple; Humans; Lysine; Mice; Molecular Sequence Data; Mutant Proteins; Mutation; Nedd4 Ubiquitin Protein Ligases; Neoplasm Staging; Polyps; Protein Structure, Secondary; Protein Transport; PTEN Phosphohydrolase; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases	2007
Absolute configuration and antitumor activity of myxochelin A produced by Nonomuraea pusilla TP-A0861. The Journal of antibiotics, 2006, Volume: 59, Issue:11 Topics: Actinobacteria; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Lysine; Mice; Microscopy, Electron, Scanning; Nuclear Magnetic Resonance, Biomolecular; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism	2006
Five Stabilized 111In-labeled neurotensin analogs in nude mice bearing HT29 tumors. Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:3 Topics: Analysis of Variance; Animals; Colonic Neoplasms; Humans; Indium Radioisotopes; Kidney; Lysine; Male; Mice; Mice, Nude; Neurotensin; Oligopeptides; Pentetic Acid; Radiography; Tissue Distribution; Transplantation, Heterologous	2007
Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis. Investigational new drugs, 2008, Volume: 26, Issue:6 Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anticarcinogenic Agents; Antigens, Nuclear; Antioxidants; Biomarkers, Tumor; Bread; Carcinogens; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Lysine; Male; Precancerous Conditions; Pyrroles; Random Allocation; Rats; Rats, Wistar	2008
MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells. Cancer research, 2008, Apr-15, Volume: 68, Issue:8 Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Molecular Sequence Data; Mucin-1; Pancreatic Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm	2008
Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. Journal of cellular and molecular medicine, 2008, Volume: 12, Issue:2 Topics: Acetylation; Annexin A5; Apoptosis; Cell Cycle; Cell Line, Tumor; Chromatin Immunoprecipitation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; G2 Phase; HCT116 Cells; Histones; Humans; Hydrogen Peroxide; Hydroxamic Acids; Lysine; Mitosis; Models, Biological; Promoter Regions, Genetic; Time Factors; Transcriptional Activation; Tumor Suppressor Protein p53	2008
Induction of heat shock proteins and the proteasome system by casein-N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)lysine in Caco-2 cells. Annals of the New York Academy of Sciences, 2008, Volume: 1126 Topics: Adenocarcinoma; Blotting, Western; Caco-2 Cells; Caseins; Cell Line, Tumor; Colonic Neoplasms; Glycation End Products, Advanced; Humans; Lysine; Mass Spectrometry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2008
The transport of lysine across monolayers of human cultured intestinal cells (Caco-2) depends on Na(+)-dependent and Na(+)-independent mechanisms on different plasma membrane domains. The Journal of nutrition, 1995, Volume: 125, Issue:10 Topics: Adenocarcinoma; Biological Transport, Active; Cell Membrane; Colonic Neoplasms; Humans; Intestinal Absorption; Intestinal Mucosa; Lysine; Membrane Potentials; Models, Biological; Regression Analysis; Sodium; Tumor Cells, Cultured	1995
Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives. Cancer research, 1995, Sep-01, Volume: 55, Issue:17 Topics: Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Immunoglobulin Fab Fragments; Kidney Neoplasms; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Proteins; Technetium; Transplantation, Heterologous; Tumor Cells, Cultured	1995
Broad cytolytic specificity of myotoxin II, a lysine-49 phospholipase A2 of Bothrops asper snake venom. Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:11 Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Bothrops; Colonic Neoplasms; Crotalid Venoms; Cytoplasm; Dose-Response Relationship, Drug; Endothelium, Vascular; Group II Phospholipases A2; Heparin; Humans; Isoenzymes; Leukemia, Monocytic, Acute; Lysine; Mice; Muscle, Skeletal; Neuraminidase; Neurotoxins; Phospholipases A; Phospholipases A2; Protamines; Rats; Reptilian Proteins; Rhabdomyosarcoma; Spleen; Tumor Cells, Cultured; Tunicamycin	1994
Pretargeted tumour imaging with streptavidin immunoconjugates of monoclonal antibody CC49 and 111In-DTPA-biocytin. Nuclear medicine and biology, 1996, Volume: 23, Issue:4 Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bacterial Proteins; Colonic Neoplasms; Female; Glycoproteins; Humans; Immunoconjugates; Indium Radioisotopes; Lysine; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Radionuclide Imaging; Streptavidin; Tissue Distribution; Transplantation, Heterologous	1996
A parenteral nutrition regimen with ornithine substituted for arginine alters the amino acid, but not polyamine, content of the ward colon tumor. Nutrition and cancer, 1997, Volume: 27, Issue:1 Topics: Amino Acids; Animals; Arginine; Colonic Neoplasms; Lysine; Male; Ornithine; Parenteral Nutrition; Polyamines; Rats; Rats, Inbred F344	1997
Lysine-directed conjugation of ethidium homodimer to B72.3 antibody: retention of immunoreactivity but altered tumor targeting. Nuclear medicine and biology, 1998, Volume: 25, Issue:3 Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Carbon Radioisotopes; Colonic Neoplasms; Dimerization; Ethidium; Humans; Indicators and Reagents; Iodine Radioisotopes; Lysine; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Tissue Distribution	1998
[Effect of lysine clonixinate and indomethacin on lipoxygenase and cyclooxygenase activity in colon isolated from cancer patients]. Medicina, 1998, Volume: 58, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Indomethacin; Lipoxygenase Inhibitors; Lysine; Prostaglandin-Endoperoxide Synthases	1998
A radioiodinated biocytin derivative for in-vivo applications. Nuclear medicine communications, 1998, Volume: 19, Issue:10 Topics: Animals; Avidin; Benzoates; Colonic Neoplasms; Female; Humans; Iodine Radioisotopes; Kidney; Lysine; Mice; Mice, Inbred Strains; Mice, Nude; Radionuclide Imaging; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured	1998
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma. Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3 Topics: 3T3 Cells; Adenine; Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; Genes, ras; Humans; Lysine; Mice; Mice, Nude; Point Mutation; Recombinant Proteins; Transfection; Xenograft Model Antitumor Assays	2000
RAGE expression and AGE-induced MAP kinase activation in Caco-2 cells. Biochemical and biophysical research communications, 2001, Nov-16, Volume: 288, Issue:5 Topics: Adenocarcinoma; Blotting, Western; Caco-2 Cells; Caseins; Colonic Neoplasms; Enzyme Activation; Glycation End Products, Advanced; Glycoside Hydrolases; Hot Temperature; Humans; Lysine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Denaturation; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transcription, Genetic	2001
[Effect of nonsteroidal antiinflammatory drugs on colonic lipoxygenase and cyclooxygenase activities from patients with colonic neoplasia]. Medicina, 2001, Volume: 61, Issue:5 Pt 1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Clonixin; Colon; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Isoenzymes; Lipoxygenase Inhibitors; Lysine; Membrane Proteins; Prostaglandin-Endoperoxide Synthases	2001
Predictive assays for tumor response to single and multiple fractions of hyperthermia. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 109 Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Concanavalin A; Cyclic AMP; Heat-Shock Proteins; Humans; Hyperthermia, Induced; Lysine; Membrane Glycoproteins; Neoplasm Proteins; Predictive Value of Tests; Protein Biosynthesis	1988