Page last updated: 2024-08-17

lysine and Cirrhosis

lysine has been researched along with Cirrhosis in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (15.15)18.2507
2000's6 (18.18)29.6817
2010's9 (27.27)24.3611
2020's13 (39.39)2.80

Authors

AuthorsStudies
Agborbesong, E; Li, LX; Li, X; Zhang, L; Zhang, X; Zhou, JX1
Jiao, LM; Li, YL; Liu, HM; Qi, YR; Tang, K; Wang, TC; Wang, ZW; Xu, JL; Yu, B; Zhao, W1
Chamadol, N; Ho, PN; Khuntikeo, N; Klanrit, P; Kulthawatsiri, T; Loilome, W; Namwat, N; Phetcharaburanin, J; Sirirattanakul, S; Suksawat, M; Titapun, A; Treeriya, R; Wangwiwatsin, A1
Kang, L; Liang, Z; Wang, X; Xiang, J; Yang, G; Yang, S1
Ediga, HH; Hester, P; Madala, SK; Reddy, GB; Yepuri, A1
Chen, W; Fan, J; Huang, F; Li, H; Lu, M; Mao, H; Peng, X; Wang, Y; Xiong, L; Yu, X; Zhong, Z; Zhou, Y1
Cao, L; Qian, H; Sun, Y; Wu, S; Zhang, N; Zhang, Y1
Arai, T; Hoshi, T; Nishio, T; Nogami, M; Toukairin, Y1
John, R; Konvalinka, A; Pei, Y; Scholey, JW; Song, X; Williams, VR; Zhou, X1
Barozzino, M; Casagrande, V; Castellano, G; Cinefra, C; Conserva, F; Divella, C; Federici, M; Gallone, A; Gesualdo, L; Giorgino, F; Menghini, R; Pesce, F; Pontrelli, P; Rossini, M; Simone, S; Stallone, G; Stasi, A1
Bayliss, G; Guan, Y; Li, X; Liu, F; Liu, L; Xiong, C; Zhang, C; Zhao, TC; Zhuang, S; Zou, J1
Adeyeye, M; Castellon, A; Dawson, B; Eyre, DR; Grol, MW; Keene, DR; Krakow, D; Lee, BH; Lietman, C; Lim, J; Park, D; Rai, J; Schweitzer, R; Weis, M1
Hu, J; Liu, J; Tan, L; Wu, X; Zhou, Q1
Cheng, P; Gu, Y; Lai, L; Xue, J; Yan, M1
Rieder, F; Sadler, T; Scarpa, M; Stylianou, E; West, G1
Brouwers, O; de Vos-Houben, JM; Hageman, G; Janssen, BJ; Miyata, T; Niessen, PM; Schalkwijk, CG; Stehouwer, CD; van Nieuwenhoven, F1
Long, CS; McKinsey, TA; Schuetze, KB1
Andrews, C; Balasubramanian, R; Chan, WM; Chew, S; Engle, EC; Kang, PB; MacKinnon, SE1
Han, J; Tan, C; Tan, D; Wang, Y; Yang, S1
Begieneman, MP; Krijnen, PA; Kubat, B; Niessen, HW; Paulus, WJ; Rijvers, L; Schalkwijk, CG; Stooker, W; van Rossum, AC; Vonk, AB1
Arihiro, K; Doi, S; Doi, T; Irifuku, T; Kohno, N; Masaki, T; Nakashima, A; Sasaki, K; Ueno, T; Yamada, K1
Gaikwad, AB; Goru, SK; Kadakol, A; Malek, V; Pandey, A; Sharma, N1
Adam, AG; Baddour, NM; El Nahas, AM; El-Koraie, AF; Griffin, M; Johnson, TS; Njloma, M; Skill, NJ1
Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC1
Cailhier, JF; Clay, S; Ferenbach, D; Houlberg, K; Hughes, J; Kipari, T; Savill, J; Walbaum, D; Watson, S1
Ansorge, S; Faust, J; Gollnick, HP; Lindenlaub, P; Neubert, K; Reinhold, D; Schultze, B; Simeoni, L; Thielitz, A; Vetter, RW; Wrenger, S1
Bajpai, P; Benghuzzi, H; Butler, K; Cason, Z; England, B; Puckett, A; Tucci, M1
Bresson-Hadni, S; Carbillet, JP; Grenard, P; Humbert, P; Ricard-Blum, S; Risteli, L; Vuitton, DA1
Esterre, P; Hartmann, DJ; Ricard-Blum, S1
Ando, A; Fukunaga, M; Hori, M; Imai, E; Kawada, N; Kurokawa, K; Miyata, T; Moriyama, T1
Açil, Y; Bätge, B; Brinckmann, J; Fietzek, PP; Müller, PK; Notbohm, H; Schmeller, W; Tronnier, M1
Aricó, CN; Bernich, P; Brezzi, B; Lapolla, A; Lupo, A; Maiorca, P; Marcantoni, C; Maschio, G; Rugiu, C1
Fukuma, T; Hara, T; Hirata, K; Hirata, M; Kage, M; Zhang, M1

Reviews

2 review(s) available for lysine and Cirrhosis

ArticleYear
Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.
    Journal of molecular and cellular cardiology, 2014, Volume: 70

    Topics: Acetylation; Animals; Arrhythmias, Cardiac; Fibrosis; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Lysine; Molecular Targeted Therapy; Myocardium; Myofibroblasts; Protein Processing, Post-Translational; Signal Transduction

2014
The dialytic failure of the peritoneal membrane.
    Contributions to nephrology, 2001, Issue:131

    Topics: Aquaporin 1; Aquaporins; Arginine; Basement Membrane; Biological Transport; Blood Group Antigens; Body Water; Cross-Sectional Studies; Diabetic Angiopathies; Dialysis Solutions; Drug Packaging; Equipment Design; Female; Fibrosis; Glucose; Glycation End Products, Advanced; Glycosylation; Humans; Longitudinal Studies; Lysine; Male; Membrane Proteins; Molecular Weight; Osmotic Pressure; Oxidation-Reduction; Peritoneal Dialysis; Peritoneum; Peritonitis; Permeability; Sterilization; Time Factors; Treatment Failure

2001

Other Studies

31 other study(ies) available for lysine and Cirrhosis

ArticleYear
Cross talk between lysine methyltransferase Smyd2 and TGF-β-Smad3 signaling promotes renal fibrosis in autosomal dominant polycystic kidney disease.
    American journal of physiology. Renal physiology, 2022, 08-01, Volume: 323, Issue:2

    Topics: Animals; Cysts; Fibrosis; Histones; Kidney; Lysine; Methyltransferases; Mice; NIH 3T3 Cells; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Rats; Smad3 Protein; Transforming Growth Factor beta

2022
Discovery of Novel Pyrazole-Based KDM5B Inhibitor
    Journal of medicinal chemistry, 2022, 10-13, Volume: 65, Issue:19

    Topics: Animals; DNA-Binding Proteins; Fibrosis; Isoproterenol; Jumonji Domain-Containing Histone Demethylases; Lysine; Mice; Myocardium; Pyrazoles

2022
    PeerJ, 2023, Volume: 11

    Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Fibrosis; Gastrointestinal Microbiome; Humans; Lysine; Methanol; Proton Magnetic Resonance Spectroscopy; Risk Factors

2023
SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells.
    Cell death & disease, 2023, 09-30, Volume: 14, Issue:9

    Topics: Epithelial Cells; Fibrosis; Humans; Lysine; Renal Insufficiency, Chronic; Sirtuin 2; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1

2023
Nε-Carboxymethyl-Lysine Modification of Extracellular Matrix Proteins Augments Fibroblast Activation.
    International journal of molecular sciences, 2023, Oct-31, Volume: 24, Issue:21

    Topics: Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Lysine

2023
Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis.
    Cell death & disease, 2020, 01-16, Volume: 11, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Dynamins; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Histones; Humans; Kidney; Lysine; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Phosphorylation; Phosphoserine; Proliferating Cell Nuclear Antigen; Promoter Regions, Genetic; Protein Binding; Rats; Reactive Oxygen Species; Transforming Growth Factor beta1

2020
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
    Cell death and differentiation, 2020, Volume: 27, Issue:9

    Topics: Animals; Cardiomegaly; Fibrosis; Heart Failure; Humans; Isoproterenol; Leupeptins; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Myocardium; Poly ADP Ribosylation; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Ventricular Remodeling

2020
Immunohistochemistry of advanced glycation end product N
    BMC research notes, 2020, May-12, Volume: 13, Issue:1

    Topics: Adult; Aged; Atherosclerosis; Atrial Remodeling; Autopsy; Coronary Vessels; Female; Fibrosis; Forensic Pathology; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Natriuretic Peptides; Young Adult

2020
Connectivity mapping of a chronic kidney disease progression signature identified lysine deacetylases as novel therapeutic targets.
    Kidney international, 2020, Volume: 98, Issue:1

    Topics: Animals; Disease Progression; Fibrosis; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Lysine; Mice; Renal Insufficiency, Chronic

2020
Inhibition of Lysine 63 Ubiquitination Prevents the Progression of Renal Fibrosis in Diabetic DBA/2J Mice.
    International journal of molecular sciences, 2021, May-14, Volume: 22, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Female; Fibrosis; Lysine; Mice; Mice, Inbred DBA; Nitrofurans; Ramipril; Sulfones; Ubiquitination

2021
Critical roles of SMYD2 lysine methyltransferase in mediating renal fibroblast activation and kidney fibrosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:7

    Topics: Animals; Benzoxazines; beta-Alanine; Cell Proliferation; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Histone-Lysine N-Methyltransferase; Kidney; Kidney Diseases; Lysine; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Phosphorylation; Rats; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Ureteral Obstruction

2021
Localized chondro-ossification underlies joint dysfunction and motor deficits in the
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-22, Volume: 118, Issue:25

    Topics: Animals; Animals, Newborn; Chondrocytes; Chondrogenesis; Collagen Type I; Disease Models, Animal; Fibrosis; Gait; Gene Deletion; Gene Expression Regulation; Hedgehog Proteins; Hydroxylation; Inflammation; Joints; Ligaments; Lysine; Mice; Models, Biological; Motor Activity; Ossification, Heterotopic; Osteogenesis; Osteogenesis Imperfecta; Peptides; Sequence Analysis, RNA; Signal Transduction; Tacrolimus Binding Proteins; Tendons

2021
Abnormalities in lysine degradation are involved in early cardiomyocyte hypertrophy development in pressure-overloaded rats.
    BMC cardiovascular disorders, 2021, 08-21, Volume: 21, Issue:1

    Topics: Animals; Aorta, Thoracic; Arterial Pressure; Disease Models, Animal; Energy Metabolism; Fibrosis; Hypertrophy, Left Ventricular; Ligation; Lysine; Male; Metabolome; Metabolomics; Myocardium; Proteolysis; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left; Ventricular Remodeling

2021
Aldosterone induces renal fibrosis by promoting HDAC1 expression, deacetylating H3K9 and inhibiting klotho transcription.
    Molecular medicine reports, 2019, Volume: 19, Issue:3

    Topics: Acetylation; Adult; Aged; Aged, 80 and over; Aldosterone; Animals; Down-Regulation; Female; Fibronectins; Fibrosis; Glucuronidase; Histone Deacetylase 1; Histones; Humans; Kidney; Kidney Tubules; Klotho Proteins; Lysine; Male; Mice; Middle Aged; Renal Insufficiency, Chronic; Transcription, Genetic; Up-Regulation

2019
Cytokine-induced chromatin modifications of the type I collagen alpha 2 gene during intestinal endothelial-to-mesenchymal transition.
    Inflammatory bowel diseases, 2013, Volume: 19, Issue:7

    Topics: Blotting, Western; Cells, Cultured; Chromatin; Chromatin Immunoprecipitation; Collagen Type I; DNA Methylation; Endothelium, Vascular; Fibrosis; Histones; Humans; Interleukin-1beta; Intestinal Mucosa; Lysine; Mesoderm; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase II; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2013
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
    International journal of molecular sciences, 2013, Jul-29, Volume: 14, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling

2013
Expanding the phenotypic spectrum and variability of endocrine abnormalities associated with TUBB3 E410K syndrome.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:3

    Topics: Adult; Aged; Amino Acid Substitution; Child; Child, Preschool; Developmental Disabilities; Endocrine System Diseases; Eye Diseases, Hereditary; Female; Fibrosis; Glutamic Acid; Humans; Kallmann Syndrome; Lysine; Male; Ophthalmoplegia; Pedigree; Phenotype; Syndrome; Tubulin

2015
Betanin reduces the accumulation and cross-links of collagen in high-fructose-fed rat heart through inhibiting non-enzymatic glycation.
    Chemico-biological interactions, 2015, Feb-05, Volume: 227

    Topics: Animals; Betacyanins; Blood Glucose; Collagen; Connective Tissue Growth Factor; Fibrosis; Fructose; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Heart; Insulin; Lysine; Male; Myocardium; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1

2015
Atrial fibrillation coincides with the advanced glycation end product N(ε)-(carboxymethyl)lysine in the atrium.
    The American journal of pathology, 2015, Volume: 185, Issue:8

    Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Female; Fibrosis; Granulocytes; Heart Atria; Humans; Lymphocytes; Lysine; Macrophages; Male; Middle Aged; Myocardium; Vascular Cell Adhesion Molecule-1

2015
Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression.
    Kidney international, 2016, Volume: 89, Issue:1

    Topics: Actins; Animals; Antibodies, Neutralizing; Azepines; Cell Line; Enzyme Inhibitors; Fibroblasts; Fibronectins; Fibrosis; Glomerulonephritis, IGA; Glucuronidase; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney; Klotho Proteins; Lysine; Male; Methylation; Mice; Quinazolines; Rats; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta1; Ureteral Obstruction

2016
H2AK119 monoubiquitination regulates Angiotensin II receptor mediated macrophage infiltration and renal fibrosis in type 2 diabetic rats.
    Biochimie, 2016, Volume: 131

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fibrosis; Histones; Imidazoles; Kidney; Lysine; Macrophages; Male; Promoter Regions, Genetic; Pyridines; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Telmisartan; Transforming Growth Factor beta1; Ubiquitination

2016
Tissue transglutaminase and the progression of human renal scarring.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:8

    Topics: Animals; Antibodies; Biopsy; Cicatrix; Cross-Linking Reagents; Extracellular Matrix; Fibrosis; Humans; Immunohistochemistry; In Situ Hybridization; Kidney; Lysine; Mice; Microscopy, Fluorescence; Retrospective Studies; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transglutaminases

2003
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:12

    Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine

2003
Nitric oxide is an important mediator of renal tubular epithelial cell death in vitro and in murine experimental hydronephrosis.
    The American journal of pathology, 2006, Volume: 169, Issue:2

    Topics: Animals; Cell Death; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Dogs; Epithelial Cells; Fibrosis; Hydronephrosis; Kidney Tubules; Lysine; Macrophage Activation; Mice; Nephritis, Interstitial; Nitric Oxide; Nitric Oxide Synthase Type II

2006
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:4

    Topics: Actins; Animals; Collagen Type I; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Lysine; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Skin; Thiazoles; Transforming Growth Factor beta1

2008
One year histopathological evaluation of fibrous tissue surrounding TCPL implants using adult rats as a model.
    Biomedical sciences instrumentation, 1997, Volume: 33

    Topics: Animals; Biocompatible Materials; Calcium Phosphates; Ceramics; Fibroblasts; Fibrosis; Foreign-Body Reaction; Inflammation; Lysine; Macrophages; Male; Neutrophils; Phosphates; Prostheses and Implants; Rats; Rats, Sprague-Dawley

1997
The level of the collagen cross-link pyridinoline reflects the improvement of cutaneous lesions in one case of skin alveolar echinococcosis.
    Parasitology research, 1998, Volume: 84, Issue:9

    Topics: Albendazole; Amino Acids; Anticestodal Agents; Antiparasitic Agents; Arginine; Biopsy; Collagen; Echinococcosis; Echinococcosis, Pulmonary; Fibrosis; Humans; Immunohistochemistry; Lysine; Skin; Skin Diseases, Parasitic

1998
Monitoring of extracellular matrix metabolism and cross-linking in tissue, serum and urine of patients with chromoblastomycosis, a chronic skin fibrosis.
    European journal of clinical investigation, 1998, Volume: 28, Issue:9

    Topics: Amino Acids; Antifungal Agents; Arginine; Biomarkers; Chromoblastomycosis; Collagen; Cross-Linking Reagents; Extracellular Matrix; Fibrosis; Humans; Hyaluronic Acid; Lysine; Naphthalenes; Skin; Terbinafine; Time Factors

1998
Increased oxidative stress in mouse kidneys with unilateral ureteral obstruction.
    Kidney international, 1999, Volume: 56, Issue:3

    Topics: Animals; Disease Models, Animal; Fibrosis; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Kidney; Lysine; Male; Membrane Proteins; Mice; Oxidative Stress; RNA, Messenger; Ureteral Obstruction

1999
Overhydroxylation of lysyl residues is the initial step for altered collagen cross-links and fibril architecture in fibrotic skin.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:4

    Topics: Aged; Collagen; Fibrosis; Glycosylation; Humans; Hydroxylation; Lysine; Microscopy, Electron; Skin; Solubility

1999
Effect of nitric oxide synthase inhibition on Schistosoma japonicum egg-induced granuloma formation in the mouse liver.
    Parasite immunology, 2001, Volume: 23, Issue:6

    Topics: Animals; Enzyme Inhibitors; Female; Fibrosis; Granuloma; Interleukin-13; Interleukin-4; Liver Diseases; Lysine; Mice; Mice, Inbred CBA; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Schistosoma japonicum; Schistosomiasis japonica

2001