Page last updated: 2024-08-17

lysine and Cell Transformation, Neoplastic

lysine has been researched along with Cell Transformation, Neoplastic in 114 studies

Research

Studies (114)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (22.81)	18.7374
1990's	6 (5.26)	18.2507
2000's	20 (17.54)	29.6817
2010's	54 (47.37)	24.3611
2020's	8 (7.02)	2.80

Authors

Authors	Studies
Cao, C; Ding, W; Gao, P; Lin, S; Meng, Y; Peng, T; Wu, P; Zhi, W	1
Allevato, MM; Ann, D; Faiola, F; Gates, R; Girke, T; Hamilton, MJ; Hung, YW; Hurd, M; Ichikawa, W; Jang, K; Martinez, E; Pan, S; Pino, J; Qi, Y; Seewaldt, V; Villalpando, E; Vorontchikhina, M; Zhao, Y	1
Gu, R; Janknecht, R; Kim, TD; Oh, S; Shin, S; Song, H; Sui, Y	1
Qi, Y; Zhao, Y	1
Chen, W; Chen, YH; Ruan, Q; Sun, H; Tang, A; Wan, X; Wang, J; Yan, D; Yang, X; Zamani, A; Zhang, H	1
Chandra, D; Gogada, R; Gundampati, RK; Hashmi, S; Jayanthi, S; Kumar, R; Lella, R; O'Malley, J; Suresh Kumar, TK; Wang, J; Yadav, N; Zhang, D	1
An, X; Liu, Y; Zhang, X; Zhu, S	1
Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W	1
Chen, J; Chen, L; Fang, H; Fang, L; Ge, X; Han, D; Jiao, C; Jin, J; Jin, X; Li, C; Li, Y; Liao, G; Liao, L; Liu, M; Liu, Z; Peng, X; Qin, HL; Teng, H; Wang, P; Wang, X; Wang, Y; Wei, Q; Weng, L; Yang, Y; Zhang, S; Zhao, B; Zhou, D; Zhou, J	1
Avadhani, NG; Basha, J; Fang, J; Garcia-Diaz, M; Glineburg, MR; Guha, M; Guja, K; Johnson, FB; Kaufman, BA; Kundu, T; Nakagawa, H; Ruthel, G; Srinivasan, S	1
Bassik, MC; Caporicci, M; Carlson, SM; Elias, JE; Francis, JW; Fuentes, ME; Gozani, O; Hausmann, S; Hulea, L; Kim, MP; Li, A; Liu, S; Lofgren, SM; Lu, J; Maitra, A; Mazur, PK; Nguyen, ND; Pillai, R; Porco, JA; Song, J; Tandoc, K; Topisirovic, I; Van Rechem, C; Wang, H; Wistuba, II	1
Allis, CD; Bagert, JD; Feng, L; Gao, J; Kundra, R; Lemiesz, AE; Muir, TW; Nacev, BA; Schultz, N; Soshnev, AA	1
Cai, J; Fang, B; Han, T; Haura, EB; Izumi, V; Jiang, S; Kim, M; Koomen, JM; Roberts, ER; Smalley, KSM; Wan, L; Yin, Q; Yin, X; Zhang, C; Zhang, G; Zheng, M	1
Chen, ZJ; Hahn, WC; Kim, E; Lock, YJ; Shen, RR; Xu, M; Zhou, AY	1
Cho, EJ; Choi, A; Han, JW; Jang, H; Jo, CH; Kim, ST; Kim, YN; Lee, HY; Lee, J; Lim, J; Park, J; Song, TY; Song, Y; Yang, JH; Yang, YJ; Youn, HD	1
Barosi, G; Campanelli, R; Catarsi, P; Massa, M; Poletto, V; Rosti, V; Vannucchi, AM; Villani, L	1
An, J; Bowden, M; Cetinbas, N; Chow, C; Gleave, M; Huang-Hobbs, H; Leprivier, G; McIntosh, LP; McKinney, S; Sorensen, PH; Tognon, C	1
Carver, BS; Chen, Y; Chi, P; Gao, D; Iaquinta, PJ; Rockowitz, S; Sawyers, CL; Scher, HI; Shamu, T; Shukla, S; Sirota, I; Wongvipat, J; Zheng, D	1
Futscher, BW; Severson, PL; Tokar, EJ; Vrba, L; Waalkes, MP	2
Debald, M; Hartmann, G; Kuhn, W; Linke, A; Schildberg, FA; Walgenbach, K; Walgenbach-Brünagel, G	1
Aparicio, SA; Berg, T; Bilenky, M; Chang, H; Cheng, SW; Gascoyne, RD; Hirst, M; Humphries, RK; Lai, CK; Lai, D; Lee, S; Lim, E; Marra, MA; Morin, GB; Morin, RD; Mungall, AJ; Oellerich, T; Rosten, P; Salmi, A; Schoeler, N; Serve, H; Thoene, S; Umlandt, P; Wee, T; Yap, D; Yue, L	1
Balabanov, S; Boettcher, S; Bokemeyer, C; Braig, M; Brümmendorf, TH; Duncan, KE; Hauber, J; Hengartner, MO; Hermans-Borgmeyer, I; Janiesch, PC; Manz, MG; Miller, KK; Pällmann, N; Preukschas, M; Schweizer, M; Sendoel, A; Sievert, H; Streichert, T; Venz, S; Walther, R	1
Deuker, MM; McMahon, M	1
Barbash, O; Butte, AJ; Dhanak, D; Garcia, BA; Gozani, O; Huddleston, M; Jansen, PW; Khatri, P; Kruger, RG; Liu, S; Mazur, PK; Reynoird, N; Sage, J; Tummino, PJ; Van Aller, GS; Vermeulen, M; Wilkinson, AW	1
DePinho, RA; Ying, H	1
Bulic, M; Calogero, RA; Carrara, M; Elemento, O; Ezponda, T; Giannopoulou, EG; Hua, Y; Jiang, Y; Kath, WL; Kelleher, NL; Licht, JD; Martinez-Garcia, E; Popovic, R; Shah, MY; Small, EC; Wang, JP; Will, CM; Zhang, Q; Zheng, Y	1
Choi, YB; Harhaj, EW	1
Liu, Q; Liu, Y; Lu, X; Luo, F; Qin, Y; Shi, L; Wang, B; Xiang, Q; Xu, W; Xu, Y	1
Bohlander, SK; Chopra, M	1
Hamamoto, R; Nakamura, Y; Saloura, V	1
Cleary, ML; Duque-Afonso, J; Goode, DL; Iwasaki, M; Kuo, HP; Schneidawind, D; Wei, MC; Weng, Z; Wong, SH; Zhu, L	1
Liu, XJ; Wang, DY; Zhu, HG; Zhu, R; Zou, LP	1
Ariyan, CE; Berger, MF; Borsu, L; Busam, KJ; Button, J; Cao, Z; Chen, Y; Chi, P; Fagin, JA; Gao, D; Hollmann, TJ; Hu, W; Ladanyi, M; Lailler, N; Landa, I; Lee, W; Merghoub, T; Murali, R; Murphy, DA; Obenauf, AC; Postow, MA; Ran, L; Sboner, A; Schwartz, GK; Scott, SN; Shah, RH; Shukla, S; Wang, L; Wiesner, T; Wong, EW; Zhang, QF; Zheng, D	1
Buechele, C; Cleary, ML; Duque-Afonso, J; Gozani, O; Hansen, L; Huang, M; Ikenouye, L; Klein, BJ; Kutateladze, TG; Li, Q; Majeti, R; Martin, GM; Onishi, M; Schneidawind, D; Shen, J; Wong, SH; Zhu, F; Zhu, L	1
Chen, D; Costa, M; Fang, L; Jin, C; Kluz, T; Sun, H; Zhang, X	1
Barletta, F; Clark, T; Dirico, K; Falahaptisheh, H; Gerber, HP; Graziani, EI; Green, M; Han, X; He, H; Koehn, F; Loganzo, F; Lucas, J; Ma, D; Musto, S; O'Donnell, CJ; Puthenveetil, S; Rago, B; Sapra, P; Subramanyam, C; Teske, J; Tumey, LN; Veneziale, R	1
Carlson, SM; Gozani, O	1
Biancucci, M; Gius, D; Jiang, H; Kang, HJ; O'Callaghan, C; Park, SH; Principe, DR; Raparia, K; Satchell, KF; Song, HY; Vassilopoulos, A; Yan, Y	1
Fang, D; Gan, H; Wang, H; Zhang, Z; Zhou, H	1
Buck, M; Chen, X; Gaile, D; Ren, X; Tsompana, M; Wang, J; Zhu, J	1
Gao, D; Inuzuka, H; Nihira, NT; North, BJ; Ogura, K; Shimizu, K; Wei, W; Zhang, J	1
Barretina, J; Chang, B; Elledge, SJ; Howley, PM; Liu, J; Macia, E; Mulligan, P; Ottinger, M; Pavlova, N; Shi, Y; Shi, YJ; Westbrook, TF	1
Arita, A; Costa, M; Li, Q; Sun, H; Zhou, X	1
Allis, CD; Casadio, F; Dormann, HL; Li, H; Luo, JL; Patel, DJ; Song, J; Wang, GG; Wang, Z	1
Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K	1
Chen, J; Coppola, D; Glozak, M; Lane, WS; Peng, L; Seto, E; Sotomayor, EM; Villagra, A; Yuan, Z	1
Lin, HK; Yang, WL; Zhang, X	1
Gururaj, AE; Hawley, RG; Kumar, R; Landberg, G; Lee, NH; Månsson, SS; Molli, PR; Natha, RS; Ohshiro, K; Pakala, SB; Ramezani, A; Rayala, SK; Wigerup, C	1
Hamazaki, Y; Han, SI; Kamitani, A; Kanai, K; Kataoka, K; Reza, HM; Yasuda, K	1
Cho, YJ; Koellhoffer, EC; Lemieux, ME; McKenna, ES; Orkin, SH; Pomeroy, SL; Roberts, CW; Shen, X; Wang, X; Wilson, BG	1
Cheng, Y; Kalland, KH; Ke, XS; Li, WC; Qu, Y; Rotter, V; Øyan, AM	1
Achille, NJ; Chang, MJ; Chou, CW; Hemenway, CS; Reisenauer, MR; Wu, H; Zeleznik-Le, NJ; Zhang, W	1
Janas, JA; Van Aelst, L	1
Armstrong, SA; Bernt, KM; Bullinger, L; Daigle, A; Faber, J; Feng, Z; Krivtsov, AV; Kung, AL; Pollock, RM; Punt, N; Richon, VM; Sinha, AU; Vempati, S; Zhu, N	1
Asai, T; Cole, PA; Deblasio, T; Gural, A; Hatlen, MA; Huang, G; Jiang, Y; Liu, F; Melnick, A; Menendez, S; Nimer, SD; Perna, F; Roeder, RG; Sun, XJ; Voza, F; Vu, L; Wang, L; Xu, H; Zhang, J; Zhao, X	1
Brans, L; Däpp, S; García Garayoa, E; Maes, V; Müller, C; Schibli, R; Tourwé, DA	1
Chen, K; Cheung, P; Garcia, BA; Gozani, O; Kioi, M; Kuo, AJ; Lauring, J; Li, W; Park, BH; Shi, X; Xi, Y; Zee, BM	1
Abbruzzese, A; Caraglia, M; Marra, M; Park, MH; Wolff, EC	1
Beverly, LJ; Erdjument-Bromage, H; Lockwood, WW; Shah, PP; Varmus, H	1
Armstrong, SA; Beverloo, HB; Bindels, EM; Delwel, R; Döhner, H; Erpelinck, C; Haanstra, JR; Havermans, M; Hudson, WA; Kersey, JH; Krivtsov, AV; Kumar, AR; Lugthart, S; Rombouts, E; Taskesen, E; Wocjtowicz, E	1
Akasu, T; Atomi, Y; Cho, HS; Dohmae, N; Field, HI; Hamamoto, R; Hayami, S; Iwai, Y; Kobayashi, T; Kogure, M; Maejima, K; Masuda, A; Nakamura, Y; Ohnuma, S; Ponder, BA; Sugiyama, M; Takawa, M; Toyokawa, G; Tsunoda, T; Ueda, K; Yamane, Y	1
Barber, MF; Chen, K; Chua, KF; Garcia, BA; Gozani, O; Kioi, M; Li, W; Michishita-Kioi, E; Moqtaderi, Z; Paredes, S; Struhl, K; Tasselli, L; Tennen, RI; Xi, Y; Young, NL	1
He, L; Song, J; Wan, Y; Zheng, Y	1
Gozani, O; Hammell, M; Joshua-Tor, L; Kuo, A; McCombie, WR; Mills, AA; Paul, S; Schalch, T; Vogel, H	1
Armstrong, SA; Banka, D; Bernt, KM; Chang, J; Chen, L; Daigle, SR; Deshpande, AJ; Dias, S; Fazio, M; Olhava, EJ; Pollock, RM; Richon, VM; Sinha, AU	1
Douvlis, Z	1
Ciechanover, A; Fajerman, I; Schwartz, AL	1
Beckman, M	1
Pierce, A; Sternberg, DW; Unwin, RD; Watson, RB; Whetton, AD	1
Cha, TL; Chen, CT; Hung, MC; Otte, AP; Ping, B; Wu, Y; Xia, W; Yang, CC; Zhou, BP	1
Golebiowski, F; Kasprzak, KS	1
Avantaggiati, ML; Beerman, T; Catania, J; Di Giovanni, S; Knights, CD; Muratoglu, S; Perez, R; Pestell, RG; Quong, AA; Swartzbeck, A; Zhang, X	1
Bommer, GT; Fearon, ER; Gonik, N; Winer, IS	1
Kagan, HM; Lucero, HA	1
Camporeale, G; Griffin, JB; Oommen, AM; Sarath, G; Zempleni, J	1
Chikova, A; Dalal, S; DiMaio, D; Lang, T; Sweasy, JB	1
McMahon, SB; Mellert, H; Murphy, ME; Sykes, SM	1
Eisenman, RN; Secombe, J	1
French, AC; Litchfield, DW; Luscher, B	1
Baek, SH; Choi, HJ; Chung, CH; Kim, JH; Kim, KI; Kim, MH; Kim, SI; Lee, JM; Lee, JS; Nam, HJ; Yang, JW	1
Conlon-Hollingshead, C; Ortwerth, BJ	1
Barber, GN; Galabru, J; Hovanessian, AG; Katze, MG; Meurs, EF	1
Buss, JE; Cochrane, CG; Der, CJ; Jackson, JH; Li, JW	1
Douglas, JL; Quinlan, MP	1
Chen, KY; Chen, ZP	1
Hirai, H; Kanda, Y; Kurokawa, M; Mitani, K; Yamagata, T; Yazaki, Y	1
Shimizu, K; Shimizu, N; Soga, H; Tanino, M; Tsukuda, K	1
Krause, MO; Stein, GS	2
Berlin, RD	1
Weber, MJ	1
Katze, JR	1
Bhargava, PM; Vigier, P	1
Lubinus, J; Zimmermann, RE	1
Bermayer, HP; Jungwirth, C; Mayr, U; Weidinger, G	1
Pearlstein, E	1
Hedgcoth, C; Juarez, D; Juarez, H; Ortwerth, BJ	1
Belford, D; Bomzer, G; Brandt-Rauf, PW; Pincus, MR	1
Levin, SD; Perlmutter, RM; Ziegler, SF	1
Pawson, T; Weinmaster, G; Zoller, MJ	1
Frank, M; Green, I; Herberman, R; Shevach, EM; Stobo, J	1
Gumińska, M; Porwit-Bóbr, Z; Stachurska, MB	1
Defendi, V; Hirai, K; Lehman, J	1
Haemmerli, G; Schnebli, HP	1
Collard, JG; Smets, LA	1
Fischer, H	1
Consigli, RA; Hedgcoth, C; Jacobson, EL; Juarez, H	1
Hung, PP; Kothari, RM; Taylor, MW; Wang, S	1
Cowden, M; Maslow, D; Mayhew, E; Poste, G; Tolson, N	1
Hedgcoth, C; Juarez, D; Juarez, H	1
Danon, D; Inbar, M; Marikovsky, Y; Sachs, L	1
Goldman, M; Griffin, AC	1
Janoff, A; Klassen, A; Troll, W	1

Reviews

10 review(s) available for lysine and Cell Transformation, Neoplastic

Article	Year
Disturbing the histone code in leukemia: translocations and mutations affecting histone methyl transferases. Cancer genetics, 2015, Volume: 208, Issue:5 Topics: Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia; Lysine; Methyltransferases; Myeloid-Lymphoid Leukemia Protein; Polycomb Repressive Complex 2; Translocation, Genetic	2015
Critical roles of non-histone protein lysine methylation in human tumorigenesis. Nature reviews. Cancer, 2015, Volume: 15, Issue:2 Topics: Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Retinoblastoma Protein; STAT3 Transcription Factor; Tumor Suppressor Protein p53	2015
Nonhistone Lysine Methylation in the Regulation of Cancer Pathways. Cold Spring Harbor perspectives in medicine, 2016, Nov-01, Volume: 6, Issue:11 Topics: Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; DNA Damage; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction	2016
Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene, 2010, Aug-12, Volume: 29, Issue:32 Topics: Animals; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Lysine; Neoplasms; Phosphoric Monoester Hydrolases; Protein Kinases; Ubiquitination	2010
eIF5A isoforms and cancer: two brothers for two functions? Amino acids, 2013, Volume: 44, Issue:1 Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Humans; Lysine; Neoplasms; Peptide Initiation Factors; Protein Isoforms; RNA-Binding Proteins	2013
Lysyl oxidase: an oxidative enzyme and effector of cell function. Cellular and molecular life sciences : CMLS, 2006, Volume: 63, Issue:19-20 Topics: Animals; Catalysis; Cell Proliferation; Cell Transformation, Neoplastic; Chemotaxis; Coenzymes; Lysine; Models, Molecular; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Substrate Specificity	2006
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell cycle (Georgetown, Tex.), 2007, Jun-01, Volume: 6, Issue:11 Topics: Acetylation; Animals; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; DNA; DNA Damage; Doxycycline; Genes, p53; Histone Acetyltransferases; Humans; Lysine; Lysine Acetyltransferase 5; Mice; Phosphatidylethanolamines; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Stress, Physiological; Tumor Suppressor Protein p53	2007
The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection. Cell cycle (Georgetown, Tex.), 2007, Jun-01, Volume: 6, Issue:11 Topics: Animals; Caenorhabditis elegans Proteins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Epigenesis, Genetic; Gene Expression Regulation; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Lysine; Mammals; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; Nucleosomes; Oxidoreductases, N-Demethylating; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Repressor Proteins; Retinoblastoma-Binding Protein 2; Saccharomyces cerevisiae Proteins; Substrate Specificity; Tumor Suppressor Proteins	2007
Microtubules and the fluidity of the cell surface. Annals of the New York Academy of Sciences, 1975, Jun-30, Volume: 253 Topics: Adenine; Animals; Binding Sites; Biological Transport; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; Fibroblasts; Leukocytes; Lysine; Macrophages; Microscopy, Electron; Microtubules; Models, Biological; Phagocytosis; Rabbits; Simian virus 40	1975
[The enzymatic linkage of fibrinogenesis and fibrinolysis (author's transl)]. Klinische Wochenschrift, 1978, Aug-15, Volume: 56, Issue:16 Topics: Aminocaproates; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Dexamethasone; Factor XII; Fibrin; Fibrinolysin; Fibrinolysis; Hemostasis; Humans; L Cells; Lysine; Mice; Peptide Hydrolases; Plasminogen; Plasminogen Activators; Receptors, Cell Surface; Simian virus 40; Streptokinase; Tranexamic Acid; Urokinase-Type Plasminogen Activator	1978

Other Studies

104 other study(ies) available for lysine and Cell Transformation, Neoplastic

Article	Year
LOXL2 small molecule inhibitor restrains malignant transformation of cervical cancer cells by repressing Cell cycle (Georgetown, Tex.), 2022, Volume: 21, Issue:17 Topics: Amino Acid Oxidoreductases; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Protein-Lysine 6-Oxidase; Uterine Cervical Neoplasms	2022
MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival. Genes & development, 2023, 10-01, Volume: 37, Issue:19-20 Topics: Acetylation; Animals; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Histone Acetyltransferases; Humans; Lysine; Mice	2023
SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A. JCI insight, 2023, Oct-23, Volume: 8, Issue:20 Topics: Carcinogenesis; Cell Transformation, Neoplastic; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Matrix Metalloproteinase 1; Methylation; Prostatic Neoplasms	2023
CBP-triggered KDM2B acetylation accelerates the carcinogenesis of colon cancer. Journal of cellular physiology, 2020, Volume: 235, Issue:3 Topics: Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; CREB-Binding Protein; F-Box Proteins; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Protein Processing, Post-Translational	2020
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. The Journal of experimental medicine, 2020, 02-03, Volume: 217, Issue:2 Topics: Acetylcysteine; Adoptive Transfer; Animals; Carcinogenesis; Cell Polarity; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myeloid Cells; Myeloid-Derived Suppressor Cells; Reactive Oxygen Species; Signal Transduction; Transfection	2020
Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer. Biochimica et biophysica acta. Molecular cell research, 2020, Volume: 1867, Issue:1 Topics: Alanine; Amino Acid Substitution; Apoptosomes; Apoptotic Protease-Activating Factor 1; Case-Control Studies; Cell Transformation, Neoplastic; Cells, Cultured; Cytochromes c; Female; Humans; Lysine; Male; Models, Molecular; Molecular Docking Simulation; Mutant Proteins; Neoplasms; Nucleotides; PC-3 Cells; Protein Binding; Protein Interaction Mapping; Protein Multimerization; Signal Transduction	2020
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2020, Feb-25, Volume: 36, Issue:2 Topics: Carcinogenesis; Cell Transformation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Oncogenes	2020
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia. Oncogene, 2020, Volume: 39, Issue:50 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic	2020
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis. Cancer cell, 2018, 07-09, Volume: 34, Issue:1 Topics: A549 Cells; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; Methylation; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Prognosis; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Signal Transduction; Transcription Factors; Tumor Burden; YAP-Signaling Proteins	2018
hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. PloS one, 2018, Volume: 13, Issue:11 Topics: Acetylation; Animals; Cell Line; Cell Transformation, Neoplastic; Chromosomal Instability; Epigenesis, Genetic; Fibroblasts; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mitochondria; Mutagenesis, Site-Directed; Mutation; Telomerase; Telomere; Telomere Shortening	2018
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Cell, 2019, 01-24, Volume: 176, Issue:3 Topics: Adult; Aged; Animals; Carcinogenesis; Cell Line; Cell Transformation, Neoplastic; Female; HEK293 Cells; Heterografts; Humans; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pancreatic Neoplasms; Peptide Elongation Factor 1; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Signal Transduction	2019
The expanding landscape of 'oncohistone' mutations in human cancers. Nature, 2019, Volume: 567, Issue:7749 Topics: Cell Transformation, Neoplastic; Histones; Humans; Lysine; Methylation; Mutation; Neoplasms; Nucleosomes; Protein Domains; Protein Processing, Post-Translational	2019
K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling. Nature communications, 2019, 04-23, Volume: 10, Issue:1 Topics: 14-3-3 Proteins; Animals; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cytokines; HEK293 Cells; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lysine; Male; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins B-raf; Repressor Proteins; Skin Neoplasms; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays	2019
IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. Cell reports, 2013, Mar-28, Volume: 3, Issue:3 Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; I-kappa B Kinase; Inhibitor of Apoptosis Proteins; Interleukin-1beta; Lysine; Mice; Molecular Sequence Data; Neoplasms, Experimental; NF-kappa B; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Ubiquitination	2013
Menin mediates epigenetic regulation via histone H3 lysine 9 methylation. Cell death & disease, 2013, Apr-11, Volume: 4 Topics: Animals; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Fibroblasts; HEK293 Cells; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Methyltransferases; Mice; Mutation; Protein Transport; Proto-Oncogene Proteins; Repressor Proteins; Signal Transduction	2013
No association between the XPD Lys751Gln (rs13181) polymorphism and disease phenotype or leukemic transformation in primary myelofibrosis. Haematologica, 2013, Volume: 98, Issue:8 Topics: Cell Transformation, Neoplastic; Cohort Studies; Genetic Variation; Glutamine; Humans; Leukemia, Myeloid, Acute; Lysine; Phenotype; Polymorphism, Genetic; Primary Myelofibrosis; Xeroderma Pigmentosum Group D Protein	2013
Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation. The Journal of biological chemistry, 2013, Sep-27, Volume: 288, Issue:39 Topics: Animals; Calorimetry; Cell Transformation, Neoplastic; ETS Translocation Variant 6 Protein; Humans; Lysine; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Mutation; NIH 3T3 Cells; Polymers; Protein Structure, Tertiary; Proto-Oncogene Proteins c-ets; Receptor, trkC; Repressor Proteins; Salts; Signal Transduction; Static Electricity; Tyrosine	2013
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nature medicine, 2013, Volume: 19, Issue:8 Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Disease Models, Animal; DNA-Binding Proteins; Genes; Histones; Humans; Lysine; Male; Mice; Oncogene Proteins; Phenotype; Principal Component Analysis; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-ets; PTEN Phosphohydrolase; Receptors, Androgen; Signal Transduction; Transcription Factors; Transcriptional Regulator ERG; Transcriptome	2013
Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation. Epigenetics, 2013, Volume: 8, Issue:10 Topics: Arsenites; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Ontology; Gene Silencing; Histones; Humans; Lysine; Nuclear Proteins; Repressor Proteins; Zinc Fingers	2013
Specific expression of k63-linked ubiquitination of calmodulin-like protein 5 in breast cancer of premenopausal patients. Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:12 Topics: Adult; Aged; Breast Neoplasms; Calcium-Binding Proteins; Cell Nucleus; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Immunoblotting; Lysine; Middle Aged; Premenopause; Tumor Cells, Cultured; Ubiquitination	2013
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis. Blood, 2014, Jun-19, Volume: 123, Issue:25 Topics: Animals; B-Lymphocytes; Blotting, Western; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Profiling; Histones; Humans; Kaplan-Meier Estimate; Lymphoma; Lymphoma, B-Cell; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Polycomb Repressive Complex 2; Proto-Oncogene Proteins c-myc; Spleen	2014
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation. Disease models & mechanisms, 2014, Volume: 7, Issue:8 Topics: 3T3 Cells; Alleles; Animals; Caenorhabditis elegans; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Senescence; Disease Models, Animal; Embryo Loss; Embryonic Development; Eukaryotic Translation Initiation Factor 5A; Fibroblasts; Gene Knockout Techniques; Hydroxylation; Lysine; Mice; Mixed Function Oxygenases; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; ras Proteins; RNA-Binding Proteins	2014
Cancer biology: Enzyme meets a surprise target. Nature, 2014, Jun-12, Volume: 510, Issue:7504 Topics: Animals; Cell Transformation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Oncogene Protein p21(ras)	2014
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature, 2014, Jun-12, Volume: 510, Issue:7504 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Pancreatic Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins A-raf; Signal Transduction	2014
Cancer signaling: when phosphorylation meets methylation. Cell research, 2014, Volume: 24, Issue:11 Topics: Animals; Cell Transformation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Oncogene Protein p21(ras)	2014
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation. PLoS genetics, 2014, Volume: 10, Issue:9 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin; DNA Methylation; Epigenesis, Genetic; Female; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mice; Mice, Inbred C57BL; Multiple Myeloma; Polycomb Repressive Complex 2; Protein Binding; RNA, Small Interfering	2014
HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation. PLoS pathogens, 2014, Volume: 10, Issue:10 Topics: Animals; Apoptosis; Cell Survival; Cell Transformation, Neoplastic; DNA Damage; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Lysine; Mass Spectrometry; Mice; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Polyubiquitin; TNF Receptor-Associated Factor 6	2014
Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract. Archives of toxicology, 2016, Volume: 90, Issue:2 Topics: Bronchi; Cell Line; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Lysine; Methylation; MicroRNAs; Mitogen-Activated Protein Kinase 7; Smoking	2016
The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential. Cancer cell, 2015, Aug-10, Volume: 28, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Interleukin Receptor Common gamma Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous	2015
Hepatitis B virus X protein induces the histone H3 lysine 9 trimethylation on the promoter of p16 gene in hepatocarcinogenesis. Experimental and molecular pathology, 2015, Volume: 99, Issue:3 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Genes, p16; Hepatitis B virus; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins	2015
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer. Nature, 2015, Oct-15, Volume: 526, Issue:7573 Topics: Alleles; Anaplastic Lymphoma Kinase; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Introns; Isoenzymes; Lysine; Methylation; Mice; Molecular Sequence Data; Molecular Weight; Neoplasms; NIH 3T3 Cells; Oncogenes; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; RNA Polymerase II; RNA, Messenger; Signal Transduction; Transcription Initiation, Genetic	2015
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia. Cancer discovery, 2016, Volume: 6, Issue:7 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Disease Models, Animal; DNA-Binding Proteins; F-Box Proteins; Female; Gene Expression Regulation, Leukemic; Heterografts; High-Throughput Nucleotide Sequencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intercellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Transcription Factors	2016
Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1. PloS one, 2016, Volume: 11, Issue:6 Topics: Acetylation; Basic Helix-Loop-Helix Transcription Factors; Carcinogens, Environmental; Cell Line; Cell Transformation, Neoplastic; Chromium; Epigenesis, Genetic; Histones; Humans; Lung; Lung Neoplasms; Lysine; Neoplasm Proteins; Up-Regulation	2016
Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads. Bioconjugate chemistry, 2016, 08-17, Volume: 27, Issue:8 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Products; Carboxylic Acids; Cell Line, Tumor; Cell Transformation, Neoplastic; Cysteine; Humans; Immunoconjugates; Lysine; Maleimides; Mice; Pyrans; Tissue Distribution	2016
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status. Oncotarget, 2016, Dec-06, Volume: 7, Issue:49 Topics: Acetylation; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HCT116 Cells; HEK293 Cells; Humans; Lung Neoplasms; Lysine; Male; Mice; Mice, Knockout; Mice, Nude; Mutation; NIH 3T3 Cells; Pancreatic Neoplasms; Phenotype; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sirtuin 2; Time Factors; Tumor Burden	2016
Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells. Cell cycle (Georgetown, Tex.), 2017, Oct-02, Volume: 16, Issue:19 Topics: Amino Acid Substitution; Cell Line, Transformed; Cell Transformation, Neoplastic; Chondrocytes; Chromatin; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Lysine; Methionine; Methylation; Mutation; Protein Processing, Post-Translational; Signal Transduction	2017
A time-series analysis of altered histone H3 acetylation and gene expression during the course of MMAIII-induced malignant transformation of urinary bladder cells. Carcinogenesis, 2017, 04-01, Volume: 38, Issue:4 Topics: Acetylation; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression; Gene Regulatory Networks; Genome; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Organometallic Compounds; Promoter Regions, Genetic; Up-Regulation; Urinary Bladder	2017
Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. Science signaling, 2017, 02-14, Volume: 10, Issue:466 Topics: A549 Cells; Acetylation; Cell Line, Tumor; Cell Transformation, Neoplastic; HCT116 Cells; HEK293 Cells; Humans; Immunoblotting; Lysine; MCF-7 Cells; Oncogenes; p300-CBP Transcription Factors; Protein Binding; Proto-Oncogene Proteins c-mdm2; RNA Interference; Sirtuin 1; Tumor Suppressor Protein p53; Ubiquitin-Specific Peptidase 7; Ubiquitination	2017
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Molecular cell, 2008, Dec-05, Volume: 32, Issue:5 Topics: Cell Transformation, Neoplastic; Co-Repressor Proteins; DNA-Binding Proteins; Down-Regulation; Epithelial Cells; HeLa Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydro-Lyases; Lysine; Methylation; Multiprotein Complexes; Nerve Tissue Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Protein Binding; Protein Methyltransferases; Proteins; Proto-Oncogene Mas; Receptor, trkC; Repressor Proteins; RNA Interference; Transcription, Genetic	2008
Effects of nickel, chromate, and arsenite on histone 3 lysine methylation. Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1 Topics: Arsenites; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromates; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Lysine; Methylation; Nickel; Potassium Compounds; Protein Processing, Post-Translational; Sodium Compounds; Time Factors	2009
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 2009, Jun-11, Volume: 459, Issue:7248 Topics: Amino Acid Motifs; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Genes, Homeobox; Hematologic Neoplasms; Hematopoiesis; Hematopoietic Stem Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Magnetic Resonance Spectroscopy; Methylation; Mice; Models, Molecular; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Protein Binding; Protein Conformation; Retinoblastoma-Binding Protein 2; Transcription, Genetic; Tumor Suppressor Proteins	2009
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity. Cancer research, 2009, May-15, Volume: 69, Issue:10 Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine	2009
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Molecular and cellular biology, 2010, Volume: 30, Issue:12 Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; HCT116 Cells; Humans; Lysine; Mice; Phosphoserine; Promoter Regions, Genetic; Protein Binding; Protein Transport; Proteins; Subcellular Fractions; Transcription Factors; Transcriptional Activation; Tumor Suppressor Protein p53	2010
Acetylation-dependent oncogenic activity of metastasis-associated protein 1 co-regulator. EMBO reports, 2010, Volume: 11, Issue:9 Topics: Acetylation; Animals; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; GTP-Binding Protein alpha Subunit, Gi2; Histone Deacetylases; Humans; Lysine; Mice; Mice, Nude; Neoplasms, Experimental; Oncogenes; ras Proteins; Repressor Proteins; Trans-Activators; Transcription, Genetic; Transplantation, Heterologous	2010
SUMOylation negatively regulates transcriptional and oncogenic activities of MafA. Genes to cells : devoted to molecular & cellular mechanisms, 2010, Sep-01, Volume: 15, Issue:9 Topics: Animals; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Chick Embryo; delta-Crystallins; Fibroblasts; Gene Expression Regulation, Developmental; HeLa Cells; Humans; Lysine; Maf Transcription Factors, Large; MafB Transcription Factor; Mice; Mutation; NIH 3T3 Cells; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcription, Genetic; Transfection	2010
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer cell, 2010, Oct-19, Volume: 18, Issue:4 Topics: Animals; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Models, Genetic; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Repressor Proteins; SMARCB1 Protein; Stem Cells; T-Lymphocytes; Transcription, Genetic; Up-Regulation	2010
Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells. BMC genomics, 2010, Nov-25, Volume: 11 Topics: Cadherins; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Histones; Humans; Lysine; Male; Prostate; Receptors, Fibroblast Growth Factor; Transcription, Genetic	2010
Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes. Cancer research, 2010, Dec-15, Volume: 70, Issue:24 Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Leukemia, Experimental; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein	2010
Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and cellular biology, 2011, Volume: 31, Issue:13 Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; DNA-Binding Proteins; Down-Regulation; Fusion Proteins, bcr-abl; Humans; Lysine; Phosphoproteins; Proteasome Endopeptidase Complex; RNA-Binding Proteins; src-Family Kinases; Ubiquitin; Ubiquitination	2011
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. Cancer cell, 2011, Jul-12, Volume: 20, Issue:1 Topics: Animals; Apoptosis; Cell Cycle; Cell Differentiation; Cell Transformation, Neoplastic; Gene Rearrangement; Genetic Loci; Hematopoiesis; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Methyltransferases; Mice; Myeloid Ecotropic Viral Integration Site 1 Protein; Myeloid Progenitor Cells; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oncogene Proteins, Fusion; Protein Processing, Post-Translational	2011
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (New York, N.Y.), 2011, Aug-05, Volume: 333, Issue:6043 Topics: Acetylation; Animals; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Core Binding Factor Alpha 2 Subunit; E1A-Associated p300 Protein; Fetal Blood; Gene Expression Profiling; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred C57BL; Mutant Proteins; Oncogene Proteins, Fusion; Preleukemia; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; RUNX1 Translocation Partner 1 Protein; Transcriptional Activation; Tumor Cells, Cultured	2011
PEGylation of (99m)Tc-labeled bombesin analogues improves their pharmacokinetic properties. Nuclear medicine and biology, 2011, Volume: 38, Issue:7 Topics: Amino Acid Sequence; Animals; Bombesin; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Lysine; Male; Mice; Molecular Weight; Octanols; Organotechnetium Compounds; Phosphates; Polyethylene Glycols; Prostatic Neoplasms; Protein Transport; Receptors, Bombesin; Structure-Activity Relationship	2011
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Molecular cell, 2011, Nov-18, Volume: 44, Issue:4 Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Mice, SCID; Multiple Myeloma; Recombinant Proteins; Repressor Proteins; Signal Transduction; Transcription, Genetic; Translocation, Genetic; Xenograft Model Antitumor Assays	2011
Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. Proceedings of the National Academy of Sciences of the United States of America, 2012, Jan-17, Volume: 109, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy-Related Proteins; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysine; Mice; Models, Biological; Protein Binding; Protein Stability; Protein Transport; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Subcellular Fractions; Survival Analysis; Ubiquitination; Ubiquitins	2012
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs. Blood, 2012, Jun-14, Volume: 119, Issue:24 Topics: Animals; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Colony-Forming Units Assay; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Gene Rearrangement; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; MDS1 and EVI1 Complex Locus Protein; Mice; Mice, Inbred C57BL; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Transcription Factors	2012
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer research, 2012, Jul-01, Volume: 72, Issue:13 Topics: Aged; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Damage; DNA Replication; Female; Histone-Lysine N-Methyltransferase; Humans; Lysine; Male; Methylation; Middle Aged; Proliferating Cell Nuclear Antigen; Real-Time Polymerase Chain Reaction; RNA, Small Interfering	2012
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature, 2012, Jul-05, Volume: 487, Issue:7405 Topics: Acetylation; Adenovirus E1A Proteins; Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chromatin; Contact Inhibition; Disease Progression; ets-Domain Protein Elk-4; Histone Deacetylases; Histones; Humans; Lysine; Mice; Neoplasm Transplantation; Nucleotide Motifs; Phenotype; Promoter Regions, Genetic; Repressor Proteins; Sirtuins; Transcription, Genetic; Transplantation, Heterologous	2012
H3K9me-enhanced DNA hypermethylation of the p16INK4a gene: an epigenetic signature for spontaneous transformation of rat mesenchymal stem cells. Stem cells and development, 2013, Jan-15, Volume: 22, Issue:2 Topics: Animals; Biomarkers; Bone Marrow; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Culture Media; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Knockdown Techniques; Histones; Lysine; Male; Mesenchymal Stem Cells; Phosphorylation; Polycomb Repressive Complex 2; Rats; Rats, Sprague-Dawley; RNA, Small Interfering	2013
Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation. Epigenetics, 2012, Volume: 7, Issue:11 Topics: Animals; Arsenic; Cadherins; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Genes, Homeobox; Histones; Humans; Lysine; Male; Mice; Mice, Nude; Multigene Family; Neoplasm Transplantation; Prostatic Neoplasms; Protein Processing, Post-Translational	2012
Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell reports, 2013, Jan-31, Volume: 3, Issue:1 Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; DNA Helicases; Genetic Loci; Genome; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasms; Neuroblastoma; Peptides; Protein Binding; Structure-Activity Relationship	2013
Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l. Blood, 2013, Mar-28, Volume: 121, Issue:13 Topics: Adenosine; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Kinesins; Lysine; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Myeloid-Lymphoid Leukemia Protein; Myosins; Oncogene Proteins, Fusion; Phenylurea Compounds	2013
Malignant tumor disease as a sub-chronic, progressive intoxication on the basis of the perpetuation of the release of amino acids, initiated by a retrograde-differentiated muscle degradation protease. Medical hypotheses, 2002, Volume: 59, Issue:5 Topics: Amino Acids; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Progression; Endopeptidases; Humans; Lysine; Models, Biological; Muscle Proteins; Muscle, Skeletal; Neoplasm Proteins; Neoplasms; Nutrition Disorders	2002
Degradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination. Biochemical and biophysical research communications, 2004, Feb-06, Volume: 314, Issue:2 Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cell-Free System; COS Cells; Cysteine Endopeptidases; DNA; DNA-Binding Proteins; DNA, Complementary; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Gene Deletion; HeLa Cells; Humans; Inhibitor of Differentiation Protein 2; Lysine; Multienzyme Complexes; Peptide Hydrolases; Plasmids; Polyubiquitin; Proteasome Endopeptidase Complex; Protein Binding; Protein Folding; Protein Structure, Tertiary; Repressor Proteins; Time Factors; Transcription Factors; Transcription, Genetic; Ubiquitin	2004
Going Ku Ku on Bax. Science of aging knowledge environment : SAGE KE, 2004, Mar-17, Volume: 2004, Issue:11 Topics: Acetylation; Animals; Antigens, Nuclear; Apoptosis; bcl-2-Associated X Protein; Cell Transformation, Neoplastic; DNA Helicases; DNA-Binding Proteins; Ku Autoantigen; Lysine; Mice; Niacinamide; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2	2004
Quantitative proteomic analysis using isobaric protein tags enables rapid comparison of changes in transcript and protein levels in transformed cells. Molecular & cellular proteomics : MCP, 2005, Volume: 4, Issue:7 Topics: Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Chromatography, Liquid; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Isotope Labeling; Lysine; Mass Spectrometry; Mice; Molecular Sequence Data; Multipotent Stem Cells; Oncogene Proteins, Fusion; Peptides; Proteome; Transcription, Genetic	2005
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science (New York, N.Y.), 2005, Oct-14, Volume: 310, Issue:5746 Topics: 3T3 Cells; Animals; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; Chromones; COS Cells; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Regulation; HeLa Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Mice; Molecular Sequence Data; Morpholines; Phosphorylation; Polycomb Repressive Complex 2; Protein Binding; Protein Methyltransferases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Transcription Factors	2005
Inhibition of core histones acetylation by carcinogenic nickel(II). Molecular and cellular biochemistry, 2005, Volume: 279, Issue:1-2 Topics: Acetates; Acetylation; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression; Histones; Humans; Lysine; Organometallic Compounds; Time Factors; Transcription, Genetic	2005
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate. The Journal of cell biology, 2006, May-22, Volume: 173, Issue:4 Topics: Acetylation; Amino Acid Sequence; Apoptosis; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Gene Expression Regulation; Genes, cdc; Humans; Lysine; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Regulatory Elements, Transcriptional; Repressor Proteins; Tumor Suppressor Protein p53	2006
Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation. The Journal of biological chemistry, 2006, Sep-08, Volume: 281, Issue:36 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; beta Catenin; Cell Line; Cell Transformation, Neoplastic; Humans; Lysine; Molecular Sequence Data; Mutation; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; TCF Transcription Factors; Transcriptional Activation; Ubiquitin; Wnt Proteins	2006
K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells. The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:11 Topics: Biotinylation; Cell Transformation, Neoplastic; Choriocarcinoma; Chromatin Immunoprecipitation; Heterochromatin; Histones; Humans; Jurkat Cells; Lysine; RNA, Small Interfering; Tumor Cells, Cultured	2007
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation. Molecular and cellular biology, 2007, Volume: 27, Issue:15 Topics: Animals; Cell Transformation, Neoplastic; DNA Polymerase beta; DNA Primers; DNA Repair; Embryo, Mammalian; Fibroblasts; Glutamic Acid; Humans; Lysine; Methyl Methanesulfonate; Mice; Mutant Proteins; Sister Chromatid Exchange; Stomach Neoplasms; Uracil	2007
Development of a stabilized form of the regulatory CK2beta subunit that inhibits cell proliferation. The Journal of biological chemistry, 2007, Oct-05, Volume: 282, Issue:40 Topics: Amino Acid Sequence; Animals; Casein Kinase II; Cell Proliferation; Cell Transformation, Neoplastic; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; HeLa Cells; Humans; Lysine; Molecular Sequence Data; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Sequence Homology, Amino Acid; Ubiquitin	2007
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-26, Volume: 104, Issue:52 Topics: ATPases Associated with Diverse Cellular Activities; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chromatin; DNA Helicases; Humans; Hydroxytestosterones; Lysine; Male; Models, Biological; Prostatic Neoplasms; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Transcription, Genetic; Ubiquitin-Conjugating Enzymes	2007
Lys-tRNA levels and cell division in mouse 3T3 cells. Experimental cell research, 1980, Volume: 128, Issue:1 Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Kinetics; Lysine; Mice; RNA, Transfer; Trypsin	1980
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; eIF-2 Kinase; Enzyme Induction; Female; Gene Expression; Gentamicins; Humans; Interferons; Lysine; Mice; Molecular Weight; Mutagenesis, Site-Directed; Neoplasms, Experimental; Protein Kinases; Recombinant Proteins; Restriction Mapping; Transfection; Tumor Cells, Cultured	1993
Polylysine domain of K-ras 4B protein is crucial for malignant transformation. Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-20, Volume: 91, Issue:26 Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; In Vitro Techniques; Lysine; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Rats; Structure-Activity Relationship	1994
Efficient nuclear localization of the Ad5 E1A 12S protein is necessary for immortalization but not cotransformation of primary epithelial cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:5 Topics: Adenovirus E1A Proteins; Adenoviruses, Human; Amino Acid Sequence; Arginine; Base Sequence; Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Mutational Analysis; Epithelial Cells; Exons; Genes, ras; Humans; Lysine; Molecular Sequence Data; Mutation; Transformation, Genetic	1994
Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells. Cancer letters, 1997, May-19, Volume: 115, Issue:2 Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Lysine; Mice; Oncogene Protein p21(ras); Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine	1997
Overexpression of the MEN/ELL protein, an RNA polymerase II elongation factor, results in transformation of Rat1 cells with dependence on the lysine-rich region. The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9 Topics: 3T3 Cells; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; DNA-Binding Proteins; Epidermal Growth Factor; Fibroblasts; Gene Expression; Gene Transfer Techniques; Humans; Leukemia, Myeloid; Lysine; Mice; Mutation; Neoplasm Proteins; Peptide Elongation Factors; Proto-Oncogene Proteins c-fos; Rats; Recombinant Proteins; Retroviridae; RNA Polymerase II; RNA, Messenger; Sequence Deletion; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Elongation Factors	1998
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma. Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3 Topics: 3T3 Cells; Adenine; Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; Genes, ras; Humans; Lysine; Mice; Mice, Nude; Point Mutation; Recombinant Proteins; Transfection; Xenograft Model Antitumor Assays	2000
Properties of the genome in normal and SV40 transformed WI38 human diploid fibroblasts. II. Metabolism and binding of histones. Experimental cell research, 1975, Volume: 92, Issue:1 Topics: Acetylation; Arginine; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Genes; Histones; Humans; Lung; Lysine; Nucleoproteins; Simian virus 40; Spectrophotometry	1975
Inhibition of protease activity in cultures of rous sarcoma virus-transformed cells: effect on the transformed phenotype. Cell, 1975, Volume: 5, Issue:3 Topics: Animals; Avian Sarcoma Viruses; Biological Transport, Active; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cycloheximide; Deoxyglucose; Fibrinolysis; Fibroblasts; Lysine; Phenotype; Plasminogen; Protease Inhibitors; Protein Biosynthesis; Tosyllysine Chloromethyl Ketone; Trypsin Inhibitors	1975
Relation of cell type and cell density to the degree of post-transcriptional modification of tRNALys and tRNAPhe. Biochimica et biophysica acta, 1975, Nov-04, Volume: 407, Issue:4 Topics: Cell Count; Cell Line; Cell Transformation, Neoplastic; Lysine; Phenylalanine; Protein Biosynthesis; RNA, Transfer; Simian virus 40; Transcription, Genetic	1975
Control of the uptake of amino acids by serum chick embryo cells, untransformed or transformed rous sarcoma virus. The Journal of membrane biology, 1976, Feb-17, Volume: 26, Issue:1 Topics: Amino Acids; Arginine; Avian Sarcoma Viruses; Blood; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Kinetics; Leucine; Lysine; Protein Biosynthesis; Valine	1976
Release of interferon-induced translation inhibition by tRNA in cell-free extracts from mouse erythroleukemia cells. European journal of biochemistry, 1977, Jun-15, Volume: 76, Issue:2 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Erythroblasts; Friend murine leukemia virus; Globins; Interferons; Kinetics; L Cells; Leukemia, Erythroblastic, Acute; Liver; Lysine; Mice; Protein Biosynthesis; Rabbits; Ribosomes; RNA, Messenger; RNA, Transfer	1977
Plasma membrane glycoprotein which mediates adhesion of fibroblasts to collagen. Nature, 1976, Aug-05, Volume: 262, Issue:5568 Topics: Cell Adhesion; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Collagen; Glycoproteins; Lysine	1976
Amounts of isoaccepting lysine tRNAs change with the proliferative state of cells. Nature, 1975, Mar-27, Volume: 254, Issue:5498 Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Embryo, Mammalian; Liver; Lysine; Mice; RNA, Transfer	1975
An activating amino acid substitution in the c-abl oncogene protein fails to produce a local conformational change. Journal of protein chemistry, 1991, Volume: 10, Issue:4 Topics: Amino Acid Sequence; Cell Transformation, Neoplastic; Genes, abl; Glutamates; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Oncogene Proteins; Philadelphia Chromosome; Protein Conformation; Software	1991
Transformation of NIH 3T3 fibroblasts by an activated form of p59hck. Molecular and cellular biology, 1989, Volume: 9, Issue:6 Topics: Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; DNA; Fibroblasts; Lysine; Mice; Moloney murine leukemia virus; Mutation; Phenotype; Phosphorylation; Protein-Tyrosine Kinases; Transfection; Tyrosine	1989
A lysine in the ATP-binding site of P130gag-fps is essential for protein-tyrosine kinase activity. The EMBO journal, 1986, Volume: 5, Issue:1 Topics: Adenosine Triphosphate; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Codon; Gene Products, gag; Genes, Viral; Humans; Lysine; Mutation; Oncogenes; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Retroviridae Proteins; Species Specificity	1986
B cell, T cell and monocyte origin of the guinea pig L2C leukemia, mouse lymphomas and human leukemias and lymphoblastic cell lines. Advances in experimental medicine and biology, 1973, Volume: 29, Issue:0 Topics: Animals; Antibodies; Antibody Formation; Antilymphocyte Serum; B-Lymphocytes; Binding Sites, Antibody; Carbon Radioisotopes; Cell Transformation, Neoplastic; Chromium Radioisotopes; Complement System Proteins; Cytotoxicity Tests, Immunologic; Epitopes; Fluorescent Antibody Technique; Guinea Pigs; Humans; Immune Adherence Reaction; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lymphoma; Lysine; Mice; Monocytes; Rabbits; T-Lymphocytes	1973
Nuclear basic proteins of polyoma virus-infected cells cultivated in vitro. Acta virologica, 1973, Volume: 17, Issue:2 Topics: Animals; Arginine; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cricetinae; Electrophoresis, Polyacrylamide Gel; Histidine; Histones; Hydrochloric Acid; Kidney; Lysine; Mice; Neoplasm Proteins; Polyomavirus; Proteins; Thymus Gland	1973
Integration of simian virus 40 deoxyribonucleic acid into the deoxyribonucleic acid of primary infected Chinese hamster cells. Journal of virology, 1971, Volume: 8, Issue:5 Topics: Animals; Antigens, Viral; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; DNA; DNA, Viral; Fluorescent Antibody Technique; Leucine; Lysine; Nucleic Acid Hybridization; RNA, Viral; Simian virus 40; Sucrose; Surface-Active Agents; Thymidine; Time Factors; Tritium; Valine	1971
Protease inhibitors do not block transformed cells in the G1 phase of the cell cycle. Nature, 1974, Mar-08, Volume: 248, Issue:5444 Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chlorine; DNA; DNA, Neoplasm; Fibroblasts; Lysine; Mice; Mice, Inbred BALB C; Mitosis; Protease Inhibitors; Simian virus 40; Thymidine; Tosyl Compounds	1974
Effect of proteolytic inhibitors on growth and surface architecture of normal and transformed cells. Experimental cell research, 1974, Volume: 86, Issue:1 Topics: Agglutination Tests; Animals; Arginine; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chlorine; Concanavalin A; Contact Inhibition; Fibroblasts; Lysine; Mice; Protease Inhibitors; Simian virus 40; Tosyl Compounds	1974
Modifications in the chromosomal proteins of SV-40 transformed WI-38 human diploid fibroblasts. Biochemical and biophysical research communications, 1974, Jul-24, Volume: 59, Issue:2 Topics: Arginine; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chromosomes; Diploidy; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Histones; Humans; Lung; Lysine; Microscopy, Phase-Contrast; Molecular Weight; Nucleoproteins; Simian virus 40; Spectrophotometry; Tosyl Compounds; Tritium	1974
The SV40-induced T-antigen in mouse cells. FEBS letters, 1974, Jul-15, Volume: 43, Issue:2 Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Leucine; Lysine; Mice; Microscopy, Electron; Molecular Weight; Mycoplasma; Simian virus 40; Thymidine; Tritium; Valine	1974
An extra species of lysine transfer ribonucleic acid in polyoma virus-transformed cells in tissue culture. Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:2 Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Embryo, Mammalian; Escherichia coli; Female; Isotope Labeling; Kidney; Liver; Lysine; Mice; Polyomavirus; Pregnancy; RNA, Bacterial; RNA, Transfer; Tritium	1974
Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses. Journal of virology, 1974, Volume: 14, Issue:5 Topics: Alpharetrovirus; Amino Acyl-tRNA Synthetases; Animals; Arginine; Aspartic Acid; Avian Sarcoma Viruses; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cell-Free System; Chick Embryo; Chickens; Chromatography; Culture Techniques; Fibroblasts; Liver; Lysine; Methionine; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Satellite Viruses; Tritium	1974
Cellular binding of 3H-cytochalasin B. Journal of cellular physiology, 1974, Volume: 84, Issue:3 Topics: Animals; Avian Sarcoma Viruses; Binding Sites; Calorimetry; Carcinoma, Ehrlich Tumor; Cell Fractionation; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Colchicine; Cricetinae; Cyclohexanes; Cytochalasin B; Cytochalasins; Dactinomycin; Fibroblasts; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Mice; Mice, Inbred BALB C; Ouabain; Polyomavirus; Proteins; Rats; Simian virus 40; Surface Properties; Tritium	1974
Seven lysine isoaccepting tRNA's from polyoma virus-transformed cells. Biochemical and biophysical research communications, 1974, Nov-06, Volume: 61, Issue:1 Topics: Animals; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Fibroblasts; Lysine; Mice; Polyomavirus; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Tritium	1974
Distribution of surface charge and concanavalin A-binding sites on normal and malignant transformed cells. Experimental cell research, 1974, Volume: 89, Issue:2 Topics: Agglutination; Animals; Binding Sites, Antibody; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; Cricetinae; Culture Techniques; Electricity; Ferritins; Fibroblasts; Lymphocytes; Lymphoma; Lysine; Models, Biological; Moloney murine leukemia virus; Neoplasms, Experimental; Neuraminidase; Polymers; Rats; Simian virus 40; Surface Properties	1974
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene. Cancer research, 1970, Volume: 30, Issue:6 Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine	1970
Tumorigenesis in mouse skin: inhibition by synthetic inhibitors of proteases. Science (New York, N.Y.), 1970, Sep-18, Volume: 169, Issue:3951 Topics: Animals; Antineoplastic Agents; Arginine; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Chymotrypsin; Croton Oil; Depression, Chemical; Esters; Ketones; Lysine; Mice; Papain; Phenylalanine; Skin Neoplasms; Terpenes; Trypsin Inhibitors	1970