Compounds > lysine
Page last updated: 2024-08-17

lysine and Carcinoma, Hepatocellular

lysine has been researched along with Carcinoma, Hepatocellular in 112 studies

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199040 (35.71)18.7374
1990's4 (3.57)18.2507
2000's13 (11.61)29.6817
2010's28 (25.00)24.3611
2020's27 (24.11)2.80

Authors

AuthorsStudies
Lee, JM; Park, SC1
Wang, P; Wang, X; Wang, Y; Yan, L; Yang, K; Yu, Y; Zhang, L; Zhong, XB1
Bao, ZM; Qian, X; Shi, Y; Yao, D1
Averilla, J; Gunewardena, S; Schonfeld, M; Tikhanovich, I; Weinman, SA1
Kim, B; Park, C; Park, T1
Chen, R; Guan, X; Jia, X; Li, H; Lu, Y; Xu, J1
Liu, J; Nie, C1
Li, N; Lv, S; Ma, X; Song, T; Sun, L; Yan, Y; Zhang, E; Zhao, X; Zou, Q1
Hou, CY; Huang, CL; Lin, YJ; Ma, CY; Wang, HD; Yuh, CH1
Bai, W; Cheng, L; Liu, H; Wang, M; Wang, W; Xiong, L; Yu, K1
Cao, X; Dong, Y; Fan, Y; Hou, J; Jia, K; Li, N; Li, Y; Li, Z; Lu, S; Wang, M; Wang, S; Yang, Y; Yu, Y; Zhang, D; Zhang, L; Zhang, W; Zhou, Y1
Chen, X; Gu, X; Hong, H; Wang, H; Yuan, Y; Zhang, Z1
Bai, L; Cao, Z; Ding, C; Ding, W; Jin, J; Li, Y; Wang, D; Wang, Y; Wei, H; Xi, L; Yan, P; Zheng, X1
Gao, X; Gao, Y; Jin, D; Li, X; Liu, T; Liu, Z; Wang, X; Wei, P; Wei, X1
Chen, YS; Guo, YX; Han, B; Li, JY; Tian, T; Wu, JY; Xie, RJ; Yang, Q; Yang, T1
Dhanarajan, A; Ding, X; Gad, SA; Hou, W; Qiu, W1
Li, X; Liu, Q; Long, M; Wu, Q; Xie, X1
Das, C; Gadad, SS; Klein, BJ; Kutateladze, TG; Mondal, P; Roy, S; Sen, S; Tiwary, N1
Bock, T; Buechel, D; Christofori, G; Dazert, E; Gao, R; Hall, MN; Heim, MH; Hergovich, A; Hindupur, SK; Jeevan-Raj, B; Kalathur, RKR; Lim, DS; Matthias, P; Morini, MF; Ng, CKY; Nuciforo, S; Piscuoglio, S; Song, S; Tang, F; Terracciano, LM; Wyss, CB1
Fan, H; Li, Y; Lu, T; Mao, Y; Qian, Y; Sun, R; Yu, S; Zhang, Z; Zheng, C1
Chen, Z; Dong, S; Feng, L; Hua, Y; Liu, L; Meng, Z; Ning, Z; Shi, W1
Alaggio, R; Alisi, A; Castellano, A; D'Oria, V; De Stefanis, C; Francalanci, P; Giovannoni, I; Grimaldi, C; Romito, I1
Das, P; Kwekkeboom, J; Li, P; Li, Y; Liu, J; Ma, B; Noordam, L; Ou, X; Pan, Q; Peppelenbosch, MP; Reddy, DS; Shi, S; Smits, R; van der Laan, LJW; Verstegen, MMA; Wang, L; Zhang, R1
Aillot, L; Glendová, K; Hirsch, I; Hodek, J; Hubálek, M; Janovec, V; Langerová, H; Lubyová, B; Strunin, D; Weber, J; Zábranský, A1
Chen, Y; Huang, G; Li, J; Liu, J; Lu, J; Meng, H; Shen, M; Wu, C; Zhang, R; Zhao, L; Zhao, X; Zhou, X1
Lin, L; Liu, W; Luan, R; Song, H; Sun, N; Wang, C; Wang, M; Wang, S; Wei, S; Wu, Y; Yang, F; Zeng, K; Zhao, Y; Zhou, B; Zou, R1
Geng, Y; Wang, YF; Yang, G; Yuan, HF; Yuan, Y; Yun, HL; Zhang, XD; Zhao, LN1
Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z1
Beland, FA; de Conti, A; Dreval, K; Orisakwe, OE; Pogribny, IP; Ross, SA; Tryndyak, V1
Cai, X; Gao, X; Gu, G; Li, M; Li, Y; Shao, Z; Wang, G; Wang, P; Yang, J1
Jensen, ON; Kempf, SJ; Rogowska-Wrzesinska, A; Schwämmle, V; Tvardovskiy, A1
Ding, LH; Gao, SB; Jin, GH; Liu, JY; Ni, GY; Qiu, H; Wang, HM; Xu, B; Ye, J; Zhang, L; Zheng, QF; Zhu, LY1
Han, L; Lin, Y; Ma, D; Ma, X; Qin, Z; Qiu, Y; Sun, C; Sun, Y; You, Y; Zhao, Y; Zhu, L1
Liu, H; Ming, L; Wan, J1
Fan, H; Li, Y; Liu, Y; Yang, P; Yao, F1
Aburatani, H; Fukayama, M; Hayashi, A; Ishikawa, S; Kimura, H; Kokudo, N; Morikawa, T; Nagae, G; Nishi, A; Sakamoto, Y; Shibahara, J; Yamauchi, N1
Gao, SB; Jin, GH; Li, KL; Lin, X; Pan, CB; Xu, B; Xue, LX; Zhao, Y; Zheng, QF; Zheng, QL1
Gao, N; Wu, J; Xi, Q; Ye, W; Zhang, B; Zhang, X1
Asiki, G; Kaleebu, P; Kang, MS; Lutalo, T; Muwanika, R; Nalugoda, F; Newton, R; Nkurunziza, P; Nkwata, A; Qian, G; Seeley, J; Serwadda, D; Song, X; Ssempebwa, J; Tang, L; Wang, JS; William, JH; Xue, K1
Liu, XJ; Wang, DY; Zhu, HG; Zhu, R; Zou, LP1
Li, Z; Sun, HG; Sun, Y; Wang, FQ; Wang, XM; Xie, CR; Yin, ZY; Zhang, S; Zhao, WX1
Chan, AW; Chan, MT; Cheng, AS; Kang, W; Lai, PB; Lau, SS; Lee, SD; Lee, TL; Lee, YY; Li, MS; Li, X; Lo, KW; To, KF; Tong, JH; Tsang, DP; Wang, H; Wong, N; Wu, F; Wu, WK; Xiong, L; Xu, G; Yang, W; Yang, Y; Yip, KY; Yu, DY; Yu, J; Yu, Z1
Ganapathy, V; Gong, P; He, Z; Jing, Y; Kou, L; Luo, Q; Sun, J; Sun, M1
Fan, S; Fan, X; Hussain, M; Mei, L; Qian, Y; Shi, W; Tang, C; Wu, X; Yang, W; Yuan, L1
Bai, L; Chen, J; Duan, C; Wang, Y; Zeng, S; Zhang, T; Zhang, Z; Zhao, L1
Chen, J; Huang, AL; Liu, B; Ran, LK; Ren, JH; Tang, H; Tao, NN; Zhou, HZ1
Ebina, M; Funayama, R; Igarashi, K; Itoh-Nakadai, A; Katoh, Y; Matsumoto, M; Nakayama, K; Sato, M; Sato, Y; Unno, M1
Gong, YY; Groopman, JD; Kieszak, SM; McCoy, LF; Powers, CD; Rogers, HS; Schleicher, RL; Scholl, PF; Sutcliffe, AE; Wild, CP1
Chen, N; Chen, X; Deng, X; Hao, Y; He, F; Jia, W; Jiang, Y; Ma, J; Qian, X; Sun, W; Wei, H; Xing, B; Zhu, Y1
Hiwasa, T; Iwadate, Y; Koshida, T; Kumazawa, T; Matsutani, T; Sato, K; Shimada, H; Shinmen, N; Takiguchi, M1
Agirre, E; Alló, M; Buggiano, V; Chabot, B; de la Mata, M; Elela, SA; Eyras, E; Fededa, JP; Klinck, R; Kornblihtt, AR; Petrillo, E; Plass, M; Schor, I1
Braunschweig, T; Büttner, R; Ellinger, J; Gütgemann, I; Höller, T; Koch, LK; Kremmer, E; Lüscher, B; Magerl, C1
Chan, IH; Privalsky, ML1
Qian, G; Su, J; Tang, L; Wang, JS; Xu, L1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Cunningham, K; Donnelly, KC; Guerra, F; Johnson, NM; Kaufman, L; Marroquin-Cardona, A; Phillips, TD; Qian, G; Robinson, A; Rodriguez, M; Tietze, D; Wang, JS; Williams, JH; Wittmer, J; Xu, L1
Beretta, L; Booth, GC; Campbell, JS; Fausto, N; Lai, KK; Lohia, N; Masse, DJ; Shang, S1
Bardag-Gorce, F; Buslon, V; French, BA; French, SW; Li, J; Oliva, J; Zhong, J1
Albanes, D; Freedman, ND; Jiao, L; Moy, KA; Sinha, R; Stolzenberg-Solomon, RZ; Virtamo, J; Weinstein, SJ1
Brunovskis, P; Cooper, MJ; Fink, TL; Gedeon, CR; Hanson, RW; Hyatt, SL; Kowalczyk, TH; Li, D; Liu, G; Miller, TJ; Moen, RC; Muhammad, O; Pasumarthy, MK; Payne, JM1
KONIKOVA, AS; KOROTKINA, RN; KRITZMAN, MG1
Bonnefin, P; Feng, X; Hara, Y; Harris, CC; Joh, T; Kataoka, H; Miura, Y; Nakabayashi, H; Riabowol, K; Vaziri, H; Vieyra, D1
Chen, JY; Chen, SY; Kao, CF; Wu Lee, YH1
Loukili, N; Okano, Y; Plans, V; Scheper, J; Soler, M; Thomson, TM1
Boldogh, I; Brasier, AR; Ray, S1
El-Kadi, AO; Gharavi, N1
Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ1
Coleman, PL; Green, GD1
Chalkley, R; Louters, L1
Armstrong, VW; Brunner, C; Ernst, A; Helmhold, M; Müller, HJ; Pethö-Schramm, A1
Byus, CV; Fukumoto, GH; Hawel, L; Tjandrawinata, RR1
Beppu, T; Samejima, K; Shirahata, A1
Kawasaki, T; Ma, Y; Shida, H1
Julkunen, I; Kinnunen, L; Melen, K1
Bridle, KR; Crawford, DH; Powell, LW; Ramm, GA1
Colten, HR; Strunk, RC; Tashjian, AH1
Ezirike, J; Kim, S; Morris, HP; Paik, WK1
Balhorn, R; Chalkey, R; Granner, D; Jackson, V1
Chae, CB; Morris, HP; Smith, MC1
Iwanami, Y; Suzuki, T1
Barra, R; Beres, B; Koch, MR; Lea, MA1
Gabrielli, F; Tsugita, A1
Hekman, A; Sluyser, M1
Hnilica, LS; Hnilica, VS; Kappler, HA1
Hnilica, LS; Hurlbert, RB; Liau, MC1
Boutwell, RK; Morris, HP; Potter, VR; Schreiber, G1
Byvoet, P3
Ishiwata, Y1
Henshaw, EC; Hiatt, HH; Hirsch, CA; Milosevic, F1
Ohanian, SH; Taubman, SB; Thorbecke, GJ1
Sasada, M; Terayama, H1
Egawa, K1
Maeno, H; Rotermund, HM; Schreiber, G; Weigand, K; Weinssen, U1
Irvin, JL; Morris, HP; Strobel, HW1
Gorbacheva, LB; Kukushkina, GV1
Taylor, MW; Volkers, SA1
Kinkade, JM1
Balhorn, R; Chalkley, R; Granner, D1
Saito, M; Tsumita, T1
Balhorn, R; Chalkley, R; Granner, D; Hohmann, P; Oliver, D1
Balhorn, R; Chalkley, R; Granner, D; Oliver, D1
Hermes, Y; Sluyser, M1
Liu, LP; Ortwerth, BJ1
Carlson, JV; Ortwerth, BJ; Yonuschot, GR1
Pickart, L; Thaler, MM; Thayer, L1
Chalkley, R; Granner, D; Oliver, D1
Bustin, M; Sluyser, M1
Kot, E; Morris, HP; Schweppe, JS; Smoron, GL1
Olivotto, M; Paoletti, F1
Balhorn, R; Chalkley, R; Granner, D; Tanphaichitr, N1

Other Studies

112 other study(ies) available for lysine and Carcinoma, Hepatocellular

ArticleYear
Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma.
    Genes & genomics, 2022, Volume: 44, Issue:3

    Topics: Carcinoma, Hepatocellular; Enhancer of Zeste Homolog 2 Protein; Glucose; Humans; Liver Neoplasms; Lysine; Methylation; Protein Processing, Post-Translational; Thyroid Hormone Receptors beta

2022
Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:5

    Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury, Chronic; Cytochrome P-450 CYP3A; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 4; Histones; Humans; Liver Neoplasms; Lysine; Receptors, Steroid; Rifampin; Ritonavir; RNA, Antisense; RNA, Long Noncoding

2022
Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma.
    The Kaohsiung journal of medical sciences, 2022, Volume: 38, Issue:5

    Topics: Alpha-Globulins; Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Histone Demethylases; Humans; Liver Neoplasms; Lysine; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt

2022
Male-Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol-Induced Liver Injury and Hepatocyte Dedifferentiation.
    Hepatology communications, 2022, Volume: 6, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury, Chronic; Female; Hepatocyte Nuclear Factor 4; Hepatocytes; Liver Neoplasms; Lysine; Male; Mice

2022
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
    Briefings in bioinformatics, 2022, 09-20, Volume: 23, Issue:5

    Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine

2022
In-depth Profiling and Quantification of the Lysine Acetylome in Hepatocellular Carcinoma with a Trapped Ion Mobility Mass Spectrometer.
    Molecular & cellular proteomics : MCP, 2022, Volume: 21, Issue:8

    Topics: Acetylation; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Lysine; Mass Spectrometry; Protein Processing, Post-Translational; Proteome; Sirtuin 2

2022
KDM5B regulates the PTEN/PI3K/Akt pathway to increase sorafenib-resistance in hepatocellular carcinoma.
    Anti-cancer drugs, 2022, 10-01, Volume: 33, Issue:9

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Hep G2 Cells; Humans; Jumonji Domain-Containing Histone Demethylases; Liver Neoplasms; Lysine; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Repressor Proteins; Sorafenib; Tensins

2022
Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:9

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Histone Demethylases; Histones; Humans; Liver Neoplasms; Lysine; Proto-Oncogene Proteins c-bcl-2; Sorafenib; Tacrolimus Binding Proteins

2022
WNK1-OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer Strategy.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Animals; beta-Galactosidase; Carcinoma, Hepatocellular; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Lysine; Minor Histocompatibility Antigens; Neovascularization, Pathologic; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Rafoxanide; Transcription Factors; Tumor Suppressor Protein p53; WNK Lysine-Deficient Protein Kinase 1; Zebrafish

2022
Protein succinylation associated with the progress of hepatocellular carcinoma.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:22

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Lysine; Protein Processing, Post-Translational; Sirtuin 3; Sirtuins

2022
JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis.
    Journal of hematology & oncology, 2022, 11-04, Volume: 15, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cholesterol; Humans; Interleukin-6; Liver Neoplasms; Lysine; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease

2022
Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.
    Proteomics, 2023, Volume: 23, Issue:9

    Topics: ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Humans; Lactates; Liver Neoplasms; Lysine; Proteomics; Ubiquitin Thiolesterase

2023
SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth.
    EMBO reports, 2023, 05-04, Volume: 24, Issue:5

    Topics: Carcinoma, Hepatocellular; Cell Proliferation; Cyclins; Humans; Liver Neoplasms; Lysine; Sirtuin 3

2023
ZBTB34 is a hepatocellular carcinoma-associated protein with a monopartite nuclear localization signal.
    Aging, 2023, 08-30, Volume: 15, Issue:16

    Topics: Alanine; Carcinoma, Hepatocellular; Humans; Karyopherins; Liver Neoplasms; Lysine; MicroRNAs; Nuclear Localization Signals

2023
Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells.
    World journal of gastroenterology, 2023, Sep-14, Volume: 29, Issue:34

    Topics: Autophagy; Carcinoma, Hepatocellular; Cell Death; Histones; Humans; Liver Neoplasms; Lysine; Vorinostat

2023
Focal adhesion kinase confers lenvatinib resistance in hepatocellular carcinoma via the regulation of lysine-deficient kinase 1.
    Molecular carcinogenesis, 2024, Volume: 63, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver Neoplasms; Lysine

2024
Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma.
    Scientific reports, 2023, 10-30, Volume: 13, Issue:1

    Topics: Carcinoma, Hepatocellular; Histones; Humans; Lactic Acid; Liver Neoplasms; Lysine; Nuclear Receptor Subfamily 6, Group A, Member 1; Prognosis; Tumor Microenvironment

2023
TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark.
    Biochemistry, 2020, 02-04, Volume: 59, Issue:4

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Hep G2 Cells; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Models, Molecular; PHD Zinc Fingers; Protein Binding; Transcription Factors

2020
LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.
    Nature communications, 2019, 12-17, Volume: 10, Issue:1

    Topics: Animals; Autophagy; Beclin-1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Datasets as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Hippo Signaling Pathway; Humans; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Lysine; Mice; Mice, Knockout; Organoids; Protein Serine-Threonine Kinases; Protein Stability; Signal Transduction; Sorafenib; Tumor Suppressor Proteins; Ubiquitination; Xenograft Model Antitumor Assays

2019
High methylation levels of histone H3 lysine 9 associated with activation of hypoxia-inducible factor 1α (HIF-1α) predict patients' worse prognosis in human hepatocellular carcinomas.
    Cancer genetics, 2020, Volume: 245

    Topics: Carcinoma, Hepatocellular; Cell Nucleus; Gene Expression Regulation, Neoplastic; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Lysine; Methylation; Prognosis; Retrospective Studies; Survival Analysis; Tissue Array Analysis; Up-Regulation

2020
FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1.
    Cell communication and signaling : CCS, 2020, 06-23, Volume: 18, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; F-Box Proteins; Gene Expression Regulation, Neoplastic; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Liver Neoplasms; Lysine; Mice, Inbred BALB C; Mice, Nude; Protein Stability; Proto-Oncogene Proteins c-myc; RNA, Messenger; Transcription, Genetic; Ubiquitination

2020
Focal Adhesion Kinase (FAK) Over-Expression and Prognostic Implication in Pediatric Hepatocellular Carcinoma.
    International journal of molecular sciences, 2020, Aug-12, Volume: 21, Issue:16

    Topics: beta Catenin; Carcinoma, Hepatocellular; Cell Nucleus; Child; Enhancer of Zeste Homolog 2 Protein; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Cirrhosis; Liver Neoplasms; Lysine; Male; Methylation; Phosphorylation; Phosphotyrosine; Prognosis; Proliferating Cell Nuclear Antigen; Tumor Burden; Up-Regulation

2020
The biological process of lysine-tRNA charging is therapeutically targetable in liver cancer.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:1

    Topics: Biological Phenomena; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Lysine; Neoplasm Recurrence, Local; Transfer RNA Aminoacylation

2021
Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination.
    Cells, 2020, 11-26, Volume: 9, Issue:12

    Topics: Arginine; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; HEK293 Cells; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Humans; Lysine; Protein Processing, Post-Translational; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination; Viral Proteins

2020
HDAC8-dependent deacetylation of PKM2 directs nuclear localization and glycolysis to promote proliferation in hepatocellular carcinoma.
    Cell death & disease, 2020, 12-05, Volume: 11, Issue:12

    Topics: Acetylation; Animals; beta Catenin; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin D1; G1 Phase; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; Histone Deacetylases; Humans; Liver Neoplasms; Lysine; Male; Membrane Proteins; Mice; Middle Aged; Models, Biological; Protein Binding; Protein Transport; Repressor Proteins; S Phase; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Up-Regulation

2020
MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma.
    Cancer science, 2021, Volume: 112, Issue:5

    Topics: Acetylation; Acetylesterase; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Databases, Genetic; Down-Regulation; Estrogen Receptor alpha; Female; Heterografts; Histone Acetyltransferases; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Male; Mice; Middle Aged; Neoplasm Invasiveness; Signal Transduction; Transcriptional Activation; Ubiquitination; Up-Regulation

2021
Aspirin modulates 2-hydroxyisobutyrylation of ENO1K281 to attenuate the glycolysis and proliferation of hepatoma cells.
    Biochemical and biophysical research communications, 2021, 06-30, Volume: 560

    Topics: Antineoplastic Agents; Aspirin; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Glycolysis; Humans; Liver Neoplasms; Lysine; Phosphopyruvate Hydratase; Tumor Suppressor Proteins

2021
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
    Cell death & disease, 2021, 07-23, Volume: 12, Issue:8

    Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay

2021
Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:9

    Topics: Acetylation; Animals; Carcinoma, Hepatocellular; Cell Death; Disease Models, Animal; Histones; Humans; Liver Neoplasms; Lysine; Mice; Non-alcoholic Fatty Liver Disease

2017
Polyethylene glycol-poly(ε-benzyloxycarbonyl-l-lysine)-conjugated VEGF siRNA for antiangiogenic gene therapy in hepatocellular carcinoma.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Hepatocellular; Drug Delivery Systems; Female; Genetic Therapy; Hep G2 Cells; Humans; Liver Neoplasms; Lysine; Mice, Inbred BALB C; Nanoparticles; Polyethylene Glycols; Polylysine; Polymers; RNA, Small Interfering; Succinimides; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2017
Accumulation of histone variant H3.3 with age is associated with profound changes in the histone methylation landscape.
    Nucleic acids research, 2017, Sep-19, Volume: 45, Issue:16

    Topics: Aging; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Hepatocytes; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice, Inbred C57BL; Protein Isoforms; Protein Processing, Post-Translational

2017
Epigenetic alterations contribute to promoter activity of imprinting gene IGF2.
    Biochimica et biophysica acta. Gene regulatory mechanisms, 2018, Volume: 1861, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Hep G2 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Lysine; Methylation; Myeloid-Lymphoid Leukemia Protein; Promoter Regions, Genetic; Proto-Oncogene Proteins

2018
TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.
    Cell death & disease, 2018, 05-22, Volume: 9, Issue:6

    Topics: Anoikis; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Models, Biological; Neoplasm Invasiveness; Polyubiquitin; Proteolysis; Snail Family Transcription Factors; Tripartite Motif Proteins; Tumor Stem Cell Assay; Ubiquitin-Protein Ligases; Ubiquitination

2018
Lysine crotonylation is involved in hepatocellular carcinoma progression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Liver Neoplasms; Lysine; Mice; Mice, Inbred C57BL; Protein Processing, Post-Translational; Up-Regulation

2019
Detection and quantification of lysine acetyl-alteration using antibody microarray.
    Bioanalysis, 2013, Volume: 5, Issue:20

    Topics: Acetylation; Animals; Antibodies; Biomarkers, Tumor; Biotin; Carcinoma, Hepatocellular; Cattle; Humans; Liver Neoplasms; Lysine; Protein Array Analysis; Protein Processing, Post-Translational; Reproducibility of Results; Sensitivity and Specificity; Serum Albumin, Bovine; Streptavidin; Vascular Endothelial Growth Factor A

2013
Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acetylation; beta Catenin; Carcinoma, Hepatocellular; Fluorescent Antibody Technique; Hepatectomy; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Methylation; Multivariate Analysis; Neoplasm Invasiveness; Treatment Outcome; Tumor Suppressor Protein p53

2014
EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:10

    Topics: Animals; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mice, Nude; Polycomb Repressive Complex 2; Repressor Proteins; Signal Transduction; Transcription, Genetic; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2014
A natural antisense transcript regulates acetylcholinesterase gene expression via epigenetic modification in Hepatocellular Carcinoma.
    The international journal of biochemistry & cell biology, 2014, Volume: 55

    Topics: Acetylcholinesterase; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cisplatin; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mitomycin; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Antisense

2014
Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2015, Volume: 32, Issue:8

    Topics: Adult; Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Cohort Studies; Environmental Exposure; Female; Food Contamination; Humans; Liver Neoplasms; Longitudinal Studies; Lysine; Male; Middle Aged; Rural Population; Serum Albumin; Uganda

2015
Hepatitis B virus X protein induces the histone H3 lysine 9 trimethylation on the promoter of p16 gene in hepatocarcinogenesis.
    Experimental and molecular pathology, 2015, Volume: 99, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Genes, p16; Hepatitis B virus; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2015
Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Chi-Square Distribution; DNA Helicases; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Nerve Tissue Proteins; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction

2015
Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.
    The Journal of pathology, 2016, Volume: 238, Issue:5

    Topics: Animals; Apoptosis; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mice, Nude; Mice, Transgenic; MicroRNAs; NF-kappa B; Polycomb Repressive Complex 2; Promoter Regions, Genetic; RNA Interference; Signal Transduction; Time Factors; Trans-Activators; Transfection; Tumor Burden; Up-Regulation; Viral Regulatory and Accessory Proteins; YY1 Transcription Factor

2016
Transporter occluded-state conformation-induced endocytosis: Amino acid transporter ATB
    Journal of controlled release : official journal of the Controlled Release Society, 2016, 12-10, Volume: 243

    Topics: Amino Acid Transport System ASC; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Docetaxel; Drug Delivery Systems; Endocytosis; Hep G2 Cells; Humans; Liposomes; Liver Neoplasms; Lysine; Mice; Mice, Inbred BALB C; Minor Histocompatibility Antigens; Particle Size; Polyethylene Glycols; Taxoids

2016
SUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions.
    Cancer letters, 2017, 02-01, Volume: 386

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; HEK293 Cells; Hep G2 Cells; Hippo Signaling Pathway; Humans; Liver Neoplasms; Lysine; Mice, Nude; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; SUMO-1 Protein; Sumoylation; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins

2017
UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells.
    International journal of molecular medicine, 2017, Volume: 39, Issue:1

    Topics: Acetylation; Carcinoma, Hepatocellular; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Lysine; Protein Binding; Protein Domains; Protein Transport; Sequence Deletion; Structure-Activity Relationship; Ubiquitin-Protein Ligases

2017
Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma.
    Biochemical and biophysical research communications, 2017, 04-15, Volume: 485, Issue:4

    Topics: Acetylation; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression; Humans; Ku Autoantigen; Liver Neoplasms; Lysine; Microscopy, Fluorescence; Mitochondria; Mutation; Protein Binding; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sirtuins

2017
Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics.
    The Journal of biological chemistry, 2017, 05-12, Volume: 292, Issue:19

    Topics: Amino Acid Motifs; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation; Histones; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Proteome; RNA, Messenger; Transcriptome

2017
Human aflatoxin albumin adducts quantitatively compared by ELISA, HPLC with fluorescence detection, and HPLC with isotope dilution mass spectrometry.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:7

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Humans; Incidence; Kenya; Liver Neoplasms; Lysine; Mass Spectrometry; Reproducibility of Results

2008
Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC.
    Proteomics, 2008, Volume: 8, Issue:23-24

    Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Isotope Labeling; Liver Neoplasms; Lysine; Neoplasm Metastasis; Neoplasm Proteins; Proteome; ROC Curve; Subcellular Fractions

2008
Activation of NFAT signal by p53-K120R mutant.
    FEBS letters, 2009, Jun-18, Volume: 583, Issue:12

    Topics: Acetylation; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Esophageal Neoplasms; Genes, Reporter; Glioblastoma; Humans; Luciferases; Lysine; Mutagenesis, Site-Directed; NFATC Transcription Factors; Phosphorylation; Point Mutation; Proline Oxidase; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms

2009
Control of alternative splicing through siRNA-mediated transcriptional gene silencing.
    Nature structural & molecular biology, 2009, Volume: 16, Issue:7

    Topics: Alternative Splicing; Animals; Argonaute Proteins; Base Sequence; Carcinoma, Hepatocellular; Chromobox Protein Homolog 5; Epigenesis, Genetic; Eukaryotic Initiation Factors; Exons; Fibronectins; Gene Knockdown Techniques; HeLa Cells; Heterochromatin; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice; Oligonucleotides, Antisense; Promoter Regions, Genetic; Ribonuclease III; RNA Interference; RNA Polymerase II; RNA, Small Interfering; Transcription, Genetic

2009
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
    Human pathology, 2010, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Chi-Square Distribution; Cholangiocarcinoma; DNA-Binding Proteins; Female; Gastrointestinal Neoplasms; Histone Demethylases; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Nuclear Proteins; Pancreatic Neoplasms; Transcription Factors

2010
A conserved lysine in the thyroid hormone receptor-alpha1 DNA-binding domain, mutated in hepatocellular carcinoma, serves as a sensor for transcriptional regulation.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:1

    Topics: Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Chlorocebus aethiops; Conserved Sequence; DNA; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Lysine; Models, Molecular; Mutant Proteins; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thyroid Hormone Receptors alpha; Transcription, Genetic; Transfection

2010
Genetic variations of hepatitis B virus and serum aflatoxin-lysine adduct on high risk of hepatocellular carcinoma in Southern Guangxi, China.
    Journal of hepatology, 2010, Volume: 53, Issue:4

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; China; Environmental Exposure; Female; Genotype; Hepatitis B virus; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Risk Factors

2010
In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1.
    Experimental oncology, 2010, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Camellia sinensis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Humans; Liver Neoplasms; Lysine; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasms, Experimental; Plant Extracts; Proline; Tea; Xenograft Model Antitumor Assays

2010
Aflatoxin and PAH exposure biomarkers in a U.S. population with a high incidence of hepatocellular carcinoma.
    The Science of the total environment, 2010, Nov-01, Volume: 408, Issue:23

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Biomarkers; Carcinoma, Hepatocellular; Creatinine; Diet; Environmental Exposure; Environmental Pollutants; Female; Hepatitis, Viral, Human; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Polycyclic Aromatic Hydrocarbons; Pyrenes; Texas; Young Adult

2010
Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models.
    PLoS genetics, 2011, Volume: 7, Issue:6

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Collagen; Extracellular Matrix; Extracellular Matrix Proteins; Hydroxylation; Integrins; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Lymphokines; Lysine; Mass Spectrometry; Mice; Mice, Knockout; Platelet-Derived Growth Factor; Protein Isoforms; Proteomics; PTEN Phosphohydrolase; Up-Regulation

2011
Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.
    Experimental and molecular pathology, 2012, Volume: 92, Issue:3

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Hepatitis, Alcoholic; Hepatocytes; Histones; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Lysine; Mallory Bodies; Methylation; Mice; Microscopy, Electron; Polycomb Repressive Complex 2; Proliferating Cell Nuclear Antigen; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Transcription Factors

2012
Soluble receptor for advanced glycation end products and risk of liver cancer.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6

    Topics: Aged; Carcinoma, Hepatocellular; Finland; Glycation End Products, Advanced; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Randomized Controlled Trials as Topic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors

2013
Nanoparticles of compacted DNA transfect postmitotic cells.
    The Journal of biological chemistry, 2003, Aug-29, Volume: 278, Issue:35

    Topics: Active Transport, Cell Nucleus; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, High Pressure Liquid; Circular Dichroism; Cytoplasm; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Green Fluorescent Proteins; Humans; Intracellular Membranes; Kinetics; Light; Luciferases; Luminescent Proteins; Lysine; Microscopy, Electron; Mitosis; Nanotechnology; Neuroblastoma; Nuclear Pore; Peptides; Phosphatidylethanolamines; Plasmids; Scattering, Radiation; Time Factors; Transfection; Transgenes; Tumor Cells, Cultured

2003
THE FATE OF PARENTERALLY INJECTED 14C-RIBONUCLEASE.
    Enzymologia biologica et clinica, 1963, Volume: 45

    Topics: Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Lysine; Metabolism; Neoplasm Proteins; Neoplasms, Experimental; Pancreas; Proteins; Rats; Research; Ribonucleases; Tyrosine

1963
ING1 represses transcription by direct DNA binding and through effects on p53.
    Cancer research, 2003, Sep-15, Volume: 63, Issue:18

    Topics: Acetylation; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HCT116 Cells; Histone Deacetylases; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Lysine; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Protein Binding; Proteins; Sirtuin 1; Sirtuins; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2003
Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein.
    Oncogene, 2004, Apr-01, Volume: 23, Issue:14

    Topics: Acetylation; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Gene Expression Regulation, Viral; Genes, Tumor Suppressor; Glutathione Transferase; HeLa Cells; Hepacivirus; Humans; Lysine; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Serine; Transcription, Genetic; Tumor Suppressor Protein p53; Viral Core Proteins

2004
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation.
    Journal of cellular biochemistry, 2006, Feb-15, Volume: 97, Issue:3

    Topics: Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; HeLa Cells; Humans; Liver Neoplasms; Lysine; Molecular Sequence Data; Protein Transport; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Two-Hybrid System Techniques; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases

2006
STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen.
    Gastroenterology, 2005, Volume: 129, Issue:5

    Topics: Acetylation; Active Transport, Cell Nucleus; Acute-Phase Reaction; Angiotensinogen; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoplasm; E1A-Associated p300 Protein; Humans; Interleukin-6; Lipopolysaccharides; Liver Neoplasms; Lysine; Mice; Mice, Inbred BALB C; Mutagenesis; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Tyrosine

2005
Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: Quinone oxidoreductase 1 by tumor necrosis factor-alpha and lipopolysaccharide.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:10

    Topics: Animals; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Inflammation; Lipopolysaccharides; Liver Neoplasms; Lysine; Metalloporphyrins; Mice; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxynitrous Acid; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha

2007
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
    British journal of cancer, 2008, May-06, Volume: 98, Issue:9

    Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms

2008
A sensitive, coupled assay for plasminogen activator using a thiol ester substrate for plasmin.
    Annals of the New York Academy of Sciences, 1981, Volume: 370

    Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cattle; Dexamethasone; Fibrinolysin; Fibrinolysis; Kinetics; Liver Neoplasms; Lysine; Plasminogen Activators; Time Factors; Urokinase-Type Plasminogen Activator

1981
In vitro exchange of nucleosomal histones H2a and H2b.
    Biochemistry, 1984, Jan-31, Volume: 23, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Chromatin; Histones; Humans; Kinetics; Liver Neoplasms; Lysine; Macromolecular Substances; Micrococcal Nuclease; Nucleosomes; Temperature; Tritium

1984
Identification of two functionally distinct lysine-binding sites in kringle 37 and in kringles 32-36 of human apolipoprotein(a).
    The Journal of biological chemistry, 1995, Mar-17, Volume: 270, Issue:11

    Topics: Amino Acid Sequence; Apolipoproteins; Apoprotein(a); Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Cysteine; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Kringles; Lipoprotein(a); Liver Neoplasms; Lysine; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plasmids; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Serine; Transfection; Tryptophan; Tumor Cells, Cultured

1995
Biosynthesis and selective export of 1,5-diaminopentane (cadaverine) in mycoplasma-free cultured mammalian cells.
    The Journal of biological chemistry, 1994, Mar-11, Volume: 269, Issue:10

    Topics: Amino Acids; Animals; Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cell Line; Culture Media; Eflornithine; Insulin; Kinetics; Lipopolysaccharides; Lysine; Mice; Mycoplasma; Ornithine; Putrescine; Rats; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured

1994
Determination of covalently bound hypusine and deoxyhypusine to protein using submilligram of protein samples by HPLC.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pressure Liquid; Lysine; Protein Binding; Rats; Reference Standards; Tumor Cells, Cultured

1996
Functional expression of human mannan-binding proteins (MBPs) in human hepatoma cell lines infected by recombinant vaccinia virus: post-translational modification, molecular assembly, and differentiation of serum and liver MBP.
    Journal of biochemistry, 1997, Volume: 122, Issue:4

    Topics: Aged; Amino Acid Sequence; Animals; Biopolymers; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cloning, Molecular; Collagen; Collectins; Complement Activation; COS Cells; Humans; Hydroxylation; Liver; Lysine; Male; Mannans; Molecular Sequence Data; Proline; Protein Processing, Post-Translational; Rabbits; Recombination, Genetic; Tumor Cells, Cultured; Vaccinia virus

1997
Arginine/lysine-rich structural element is involved in interferon-induced nuclear import of STATs.
    The Journal of biological chemistry, 2001, May-11, Volume: 276, Issue:19

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Dimerization; DNA-Binding Proteins; Humans; Interferon-alpha; Interferon-gamma; Kinetics; Liver Neoplasms; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Transport; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; STAT1 Transcription Factor; STAT2 Transcription Factor; Trans-Activators; Transfection; Tumor Cells, Cultured

2001
Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis.
    Liver, 2001, Volume: 21, Issue:2

    Topics: Actins; Aged; Carcinoma, Hepatocellular; Cell Count; Fibroblasts; Hemochromatosis; Humans; Immunohistochemistry; In Situ Hybridization; Liver Neoplasms; Lysine; Male; Malondialdehyde; Middle Aged; Muscle, Smooth; Procollagen; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta

2001
Complement biosynthesis in vitro by rat hepatoma cell strains.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 114, Issue:1 Pt 2

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cycloheximide; Erythrocytes; Humans; Hydrocortisone; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Isoleucine; Leucine; Liver Neoplasms; Lysine; Male; Rabbits; Rats; Sheep; Valine

1975
S-adenosylmethionine:protein methyltransferases in hepatomas.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Adenine; Animals; Arginine; Carcinoma, Hepatocellular; Cell Nucleus; Cytosol; Histones; Liver; Liver Neoplasms; Lysine; Methionine; Methyltransferases; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Rats; Sulfuric Acids

1975
Phosphorylation of the lysine-rich histones throughout the cell cycle.
    Biochemistry, 1975, Jun-03, Volume: 14, Issue:11

    Topics: Autoradiography; Carcinoma, Hepatocellular; Cells, Cultured; Demecolcine; DNA, Neoplasm; Electrophoresis; Histones; Hydroxyurea; Liver Neoplasms; Lysine; Mitosis; Neoplasms, Experimental; Phosphates; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Tritium

1975
Lack of relationship between activity of chromatin-bound proteinase and cell growth rates.
    The Biochemical journal, 1975, Volume: 146, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Division; Chromatin; Histones; Liver; Liver Neoplasms; Lysine; Peptide Hydrolases; Rats

1975
Interaction of lysine-rich histone and DNA in chromatin structure.
    Biochimica et biophysica acta, 1975, Jul-07, Volume: 395, Issue:3

    Topics: Binding Sites; Carcinoma, Hepatocellular; Chromatin; Deoxyribonucleases; DNA; Electrophoresis, Polyacrylamide Gel; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Macromolecular Substances; Neoplasms, Experimental; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Protein Binding; Protein Denaturation; Temperature

1975
Actions of exogenous histones and other proteins on [3H]-thymidine incorporation into DNA of Novikoff hepatoma cells.
    Cytobios, 1976, Volume: 17, Issue:66

    Topics: Animals; Carcinoma, Hepatocellular; Cytosol; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Peptides; Protamines; Protein Biosynthesis; Proteins; Rats; Serum Albumin, Bovine

1976
H1(0) histones of normal and cancer human cells. Amino acid composition of H1 purified by polyacrylamide gel electrophoresis.
    Molecular and cellular biochemistry, 1986, Volume: 71, Issue:2

    Topics: Amino Acids; Arginine; Carcinoma, Hepatocellular; Cell Line; Histones; Humans; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lysine; Neoplasms

1986
Antigenic determinants on lysine-rich histones.
    Biochimica et biophysica acta, 1973, Feb-21, Volume: 295, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cattle; Complement Fixation Tests; Cross Reactions; Epitopes; Female; Fluorescent Antibody Technique; Histones; Liver; Liver Neoplasms; Lysine; Mammary Neoplasms, Experimental; Rabbits; Rats; Species Specificity; Spleen; Thymus Gland; Uterus

1973
Biosynthess of histones and acidic nuclear proteins under different conditions of growth.
    Science (New York, N.Y.), 1965, Dec-10, Volume: 150, Issue:3702

    Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chemistry Techniques, Analytical; Histones; In Vitro Techniques; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Male; Nucleoproteins; Radiometry; Rats

1965
Biosynthesis and composition of histones in Novikoff hepatoma nuclei and nucleoli.
    Science (New York, N.Y.), 1966, Apr-22, Volume: 152, Issue:3721

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Electrophoresis; Histones; In Vitro Techniques; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Radiometry; Rats

1966
Lack of secretion of serum protein by transplanted rat hepatomas.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Animals; Blood Protein Electrophoresis; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Histidine; Leucine; Liver; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Rats

1966
Metabolic integrity of deoxyribonucleohistones.
    Journal of molecular biology, 1966, Volume: 17, Issue:2

    Topics: Animals; Carbon Isotopes; Carcinoma 256, Walker; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Histones; Intestine, Small; Iodine Isotopes; Liver; Liver Neoplasms; Lysine; Rats; Sarcoma, Experimental; Spleen; Thymus Gland; Uridine

1966
Effect of different proteins (casein, gluten, zein) and supplements of amino acids (lysine, tryptophan) on hepatic injuries induced by p-dimethylaminoazobenzene.
    Medical journal of Osaka University, 1968, Volume: 18, Issue:4

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Caseins; Chemical and Drug Induced Liver Injury; Diet; Dietary Proteins; Glutens; Liver; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Tryptophan; Zein

1968
Studies of control of tissue protein levels: differential responses of tumor and liver to fasting.
    Transactions of the Association of American Physicians, 1968, Volume: 81

    Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; Fasting; Leucine; Liver; Liver Neoplasms; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Proteins; Rats; Ribosomes; RNA

1968
Rates of albumin and transferrin synthesis in vitro in rat hepatoma-derived H4II-EC cells.
    Journal of the National Cancer Institute, 1969, Volume: 43, Issue:2

    Topics: Albumins; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Division; Cell Line; Culture Techniques; Fluorescent Antibody Technique; Isoleucine; Liver; Liver Neoplasms; Lysine; Neoplasms, Experimental; Precipitin Tests; Rats; Serum Albumin, Bovine; Transferrin

1969
The nature of inhibitors of DNA synthesis in rat-liver hepatoma cells.
    Biochimica et biophysica acta, 1969, Sep-17, Volume: 190, Issue:1

    Topics: Animals; Animals, Newborn; Antineoplastic Agents; Arginase; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Ion Exchange; DNA, Neoplasm; Hepatectomy; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; Ornithine; p-Dimethylaminoazobenzene; Rats; Regeneration; Thymidine; Tissue Extracts

1969
Studies on the biosynthesis of nuclear asis proteins. I. Incorporation of L-lysine-14C in isolated rat hepatoma nuclei.
    The Japanese journal of experimental medicine, 1969, Volume: 39, Issue:1

    Topics: Acetates; Adenosine Triphosphate; Animals; Ascites; Carboxypeptidases; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography; Culture Media; Glycolysis; Histones; In Vitro Techniques; Liver; Liver Neoplasms; Lysine; Microscopy, Electron; Neoplasms, Experimental; Puromycin; Rats; Ribonucleases; Spectrophotometry; Sucrose; Trypsin; Ultracentrifugation; Ultraviolet Rays

1969
The ratio of albumin synthesis to total protein synthesis in normal rat liver, in host liver, and in Morris hepatoma 9121.
    Cancer research, 1970, Volume: 30, Issue:8

    Topics: Albumins; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Electrophoresis; Injections, Intravenous; Leucine; Liver; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Protein Binding; Protein Biosynthesis; Rats

1970
Effects of exogenous histones upon the induction of tryptophan pyrrolase and tyrosine transaminase in liver and Morris hepatomas.
    Cancer research, 1970, Volume: 30, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Animals; Carcinoma, Hepatocellular; Enzyme Induction; Histones; Hydrocortisone; Injections, Intraperitoneal; Liver; Liver Neoplasms; Lysine; Neoplasms, Experimental; Puromycin; Rats; Stimulation, Chemical; Time Factors; Transaminases; Tryptophan Oxygenase

1970
Some aspects of the mechanism of action of 1-propyl-1-nitrosourea.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chlorophyta; DNA, Neoplasm; Formates; Histones; Leukemia L1210; Liver; Liver Neoplasms; Lysine; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Protein Hydrolysates; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer; Spleen; Time Factors; Urea

1970
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
    Biochimica et biophysica acta, 1971, May-13, Volume: 238, Issue:2

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors

1971
Alterations in the transfer RNA population of hepatoma 9618A as compared with normal rat liver.
    Biochimica et biophysica acta, 1971, Dec-30, Volume: 254, Issue:3

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Leucine; Liver; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; Serine; Tritium; Tyrosine

1971
Differences in the quantitative distribution of lysine-rich histones in neoplastic and normal tissues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cattle; Chromatography, Ion Exchange; Histones; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Lysine; Male; Neoplasm Proteins; Neoplasms, Experimental; Nucleoproteins; Rats; Spectrophotometry; Spleen

1971
Lysine-rich histone phosphorylation. A positive correlation with cell replication.
    Biochemistry, 1972, Mar-14, Volume: 11, Issue:6

    Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Densitometry; Electrophoresis; Escherichia coli; Hepatectomy; Histones; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Phosphoric Acids; Rats; Urea

1972
-Aminoadipic -semialdehyde in cell nucleus, chromatin and histone.
    The Japanese journal of experimental medicine, 1972, Volume: 42, Issue:4

    Topics: Adipates; Aldehydes; Animals; Carcinoma, Hepatocellular; Cattle; Cell Nucleus; Chick Embryo; Chromatin; Chromatography, Gas; Densitometry; Electrophoresis, Paper; Histones; Hydrolysis; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Rats; Thymus Gland; Tritium

1972
Turnover of deoxyribonucleic acid, histones, and lysine-rich histone phosphate in hepatoma tissue culture cells.
    Biochemistry, 1972, Oct-10, Volume: 11, Issue:21

    Topics: Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Half-Life; Histones; Hydrolysis; Isotope Labeling; Kinetics; Liver Neoplasms; Lysine; Neoplasms, Experimental; Phosphates; Phosphoproteins; Phosphorus Isotopes; Surface-Active Agents; Thymidine; Time Factors; Tritium; Urea

1972
Molecular nature of F 1 histone phosphorylation in cultured hepatoma cells.
    Biochemistry, 1972, Oct-10, Volume: 11, Issue:21

    Topics: Carcinoma, Hepatocellular; Cell Line; Electrophoresis, Polyacrylamide Gel; Histones; Isotope Labeling; Kinetics; Liver Neoplasms; Lysine; Oxidative Phosphorylation; Phosphates; Phosphoproteins; Phosphorus Isotopes; Time Factors; Tritium; Urea

1972
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen

1972
A rat-specific lysine-rich histone.
    Biochimica et biophysica acta, 1973, Feb-21, Volume: 295, Issue:2

    Topics: Amino Acids; Animals; Bromine; Carcinoma, Hepatocellular; Cattle; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Female; Genes, Regulator; Histones; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Peptides; Rabbits; Rats; Species Specificity; Succinimides; Thymus Gland; Uterus

1973
Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and cell division in mammalian tissues.
    Biochemistry, 1973, Sep-25, Volume: 12, Issue:20

    Topics: Aging; Animals; Bone Marrow; Brain; Carcinoma, Hepatocellular; Cattle; Cell Division; Cells, Cultured; Chromatography, Ion Exchange; Female; Fetus; Lens, Crystalline; Leukemia; Liver; Liver Neoplasms; Lysine; Mice; Neoplasms, Experimental; Organ Specificity; Pancreas; Pregnancy; Rats; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet; Spleen; Swine; Tritium

1973
Properties of tRNALys4 from various tissues.
    Biochemistry, 1973, Sep-25, Volume: 12, Issue:20

    Topics: Acylation; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cats; Cell Division; Cells, Cultured; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Hydrogen-Ion Concentration; Leukemia; Liver; Liver Neoplasms; Lysine; Mice; Neoplasms, Experimental; Organ Specificity; Oxidation-Reduction; Rats; Ribosomes; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet; Spleen; Tritium

1973
A synthetic tripeptide which increases survival of normal liver cells, and stimulates growth in hepatoma cells.
    Biochemical and biophysical research communications, 1973, Sep-18, Volume: 54, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; DNA; Glycine; Histidine; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Neoplasms, Experimental; Oligopeptides; Rats; RNA; Time Factors

1973
Identification of a distinction between cytoplasmic histone synthesis and subsequent histone deposition within the nucleus.
    Biochemistry, 1974, Feb-12, Volume: 13, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Fractionation; Cell Nucleus; Cells, Cultured; Chromosomes; Cytoplasm; DNA; Electrophoresis, Polyacrylamide Gel; Histones; Liver; Liver Neoplasms; Lysine; Membranes; Mice; Neoplasms, Experimental; Phosphates; Protein Binding; Rats; Tritium

1974
Immunological specificities of lysine-rich histones from tumors.
    The Journal of biological chemistry, 1974, Apr-25, Volume: 249, Issue:8

    Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Complement Fixation Tests; Female; Histones; Humans; Liver; Liver Neoplasms; Lysine; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Organ Specificity; Peptide Fragments; Phyllodes Tumor; Rabbits; Rats; Species Specificity; Thymus Gland

1974
DNA and nucleoprotein changes in liver and tumor nuclei after irradiation.
    Oncology, 1974, Volume: 29, Issue:4

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; DNA, Neoplasm; Histones; Liver; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; Nucleoproteins; Phosphates; Phosphorus Radioisotopes; Radiation Effects; Rats; Rats, Inbred ACI; Thymidine; Time Factors

1974
Protein metabolism in tumor cells at various stages of growth in vivo.
    The Journal of cell biology, 1974, Volume: 62, Issue:3

    Topics: Animals; Ascitic Fluid; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Division; Cell Fractionation; Cell Nucleus; Liver Neoplasms; Lysine; Male; Microsomes, Liver; Mitochondria, Liver; Neoplasm Proteins; Neoplasms, Experimental; Rats; Tritium

1974
Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.
    Biochemistry, 1974, Oct-08, Volume: 13, Issue:21

    Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Enzyme Activation; Histones; Hydroxyurea; Kinetics; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Thymidine; Tritium

1974