Page last updated: 2024-08-17

lysine and Carcinogenesis

lysine has been researched along with Carcinogenesis in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	49 (59.04)	24.3611
2020's	34 (40.96)	2.80

Authors

Authors	Studies
Herlyn, M; Yang, X; Zhu, G	1
Feng, T; Gu, R; Guo, Y; Li, K; Li, Q; Li, S; Lin, P; Ou, D; Yuan, H; Zhang, J; Zhao, G	1
Chen, ES; Lam, UTF	1
Diao, H; Hao, N; Koropatnick, J; Liu, Q; Maleki Vareki, S; Min, J; Min, W; Raphael, J; Sang, Y; Wang, Z; Xiong, J; Xu, D; Zhang, Y; Zheng, X	1
Fu, Y; Ge, S; Li, F; Yu, J	1
Boruah, N; Chatterjee, A; Singh, CS; Swargiary, P	1
Cao, X; Dong, Y; Fan, Y; Hou, J; Jia, K; Li, N; Li, Y; Li, Z; Lu, S; Wang, M; Wang, S; Yang, Y; Yu, Y; Zhang, D; Zhang, L; Zhang, W; Zhou, Y	1
Cui, X; Fu, Y; Jia, J; Liu, F; Shao, W; Wang, Y; Yang, Q; Yang, Z; Zhang, L; Zheng, L	1
Chen, J; Chen, LJ; Li, CY; Liu, YJ; She, QS; Tao, F; Xu, XY; Yang, GJ; Zhong, XD; Zhu, MH	1
Gin, GE; Liao, JC; Meeks, JJ; Song, L; Tian, X; Uchio, E; Wang, B; Wu, XR; Xie, J; Xu, X; Zi, X	1
Chen, Y; Hu, J; Huang, C; Li, K; Li, X; Liu, A; Liu, L; Qiu, C; She, X; Song, D; Wan, K; Wang, G; Wang, J; Wu, Q; Xu, F; Yu, C	1
Charlesworth, MC; Chi, YI; De Assuncao, TM; Doria Jorge, S; Iovanna, J; Lomberk, G; Madden, B; Pollin, G; Urrutia, R; Zimmermann, MT	1
Gu, R; Janknecht, R; Kim, TD; Oh, S; Shin, S; Song, H; Sui, Y	1
Dai, Y; Hong, XP; Jiang, HW; Lin, LW; Liu, DZ; Tang, DE; Xu, SH; Xu, Y	1
Ge, L; Huang, X; Sang, K; Yi, T; Zhou, J; Zhou, X	1
Bailly, AP; Gartner, A; Leidecker, O; Maghames, C; Martinez-Chantar, ML; Perrin, A; Serrano-Macia, M; Trauchessec, H; Xirodimas, DP	1
Chen, W; Chen, YH; Ruan, Q; Sun, H; Tang, A; Wan, X; Wang, J; Yan, D; Yang, X; Zamani, A; Zhang, H	1
Beckedorff, F; Duffort, S; Figueroa, M; Greenblatt, S; Karl, D; Lai, F; Liu, F; Man, N; Martin, GM; Martinez, C; Martinez, CJ; Nimer, S; Roisman, A; Shiekhattar, R; Sun, J; Sun, X; Wang, L; Xu, Y; Yue, J	1
Ha, J; Jung, SM; Kim, M; Lee, J; Park, JS; Park, SH; Seo, D	1
Feng, D; Gao, J; Gao, T; Hou, Y; Huang, W; Leng, S; Liu, R; Liu, W; Qiu, R; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zhang, K; Zhang, X; Zheng, Y	1
An, X; Liu, Y; Zhang, X; Zhu, S	1
Bao, S; Chen, L; Cui, J; Guo, S; Han, Q; He, K; Huang, H; Li, A; Li, D; Li, T; Li, Y; Man, J; Mi, L; Ran, H; Rich, JN; Wang, X; Wu, J; Xiao, D; Yan, X; Yu, Y; Zhan, X; Zhang, S; Zhang, X; Zhou, T	1
Chen, R; Dou, J; Huang, J; Shu, Z; Wang, Y; Yu, J; Yuan, H; Zhang, H; Zhao, X; Zhou, A	1
Chai, P; Fan, J; Fan, X; Ge, S; Jia, R; Ni, H; Wang, S; Wang, Y; Xing, Y; Yu, J	1
Ge, Y; Jin, JY; Li, M; Li, XY; Li, YH; Li, YX; Song, SW; Tan, XD; Ye, J	1
Chen, Z; Dong, S; Feng, L; Hua, Y; Liu, L; Meng, Z; Ning, Z; Shi, W	1
Bellacosa, A; Cai, KQ; Chau, LQ; Cheng, Y; Contreras, A; Corney, DC; Du, F; Guo, D; Hu, J; Liao, S; Noronha, AM; Peri, S; Wang, Y; Wechsler-Reya, RJ; Wiest, DL; Xu, G; Yang, ZJ; Zhao, Y; Zhou, G	1
Dong, Q; He, Q; Li, Y; Lv, C; Ming, X; Wang, H; Yi, Y; Zhang, Z; Zhu, B; Zou, Z	1
Dent, SYR; Farria, AT; Koutelou, E	1
Li, X; Mao, L; Zhang, J; Zhang, Y	1
Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F	1
Chen, S; Cheng, X; Fang, W; Hao, H; Hu, X; Hua, F; Huang, D; Huang, Z; Li, Q; Liu, F; Luo, Z; Xiao, F; Zhang, X	1
Klonou, A; Markouli, M; Papavassiliou, AG; Piperi, C; Strepkos, D	1
A, D; Albrecht, S; Andrade, AF; Bajic, A; Bandopadhayay, P; Bassenden, AV; Berghuis, AM; Beroukhim, R; Blanchette, M; Bognar, L; Brandner, S; Chen, CCL; Coutelier, M; Dali, R; De Jay, N; Deshmukh, S; Dubois, F; Ekert, PG; Ellezam, B; Faury, D; Filbin, MG; Garcia, BA; Garzia, L; Gayden, T; Hadjadj, D; Hansford, JR; Harutyunyan, AS; Hauser, P; Hébert, S; Jabado, N; Jawhar, W; Jessa, S; Jones, DTW; Juretic, N; Karamchandani, J; Khuong-Quang, DA; Kleinman, CL; Klekner, A; Korshunov, A; Kramm, C; Krskova, L; Ligon, KL; Lisi, V; Mack, SC; Maestro, N; Marchione, DM; Mikael, LG; Pathania, M; Pfister, SM; Russo, C; Salomoni, P; Sturm, D; Sumerauer, D; Suzuki, H; Taylor, MD; Vanova, K; Vicha, A; Virga, J; Weil, AG; Woodward, E; Zamecnik, J; Zapotocky, M; Zeinieh, M; Ziegler, DS	1
Gu, W; Kon, N; Li, H; Ou, Y; Rustgi, AK; Wang, SJ	1
An, N; Chen, XJ	1
Chen, L; da Silva, SR; Gao, SJ; Ju, E; Li, T; Wang, X; Wei, S; Zhang, X	1
Allis, CD; Chen, H; Chen, X; Lu, C; Majewski, J; Rajagopalan, KN; Weinberg, DN	1
Bernard, BJ; Burkitt, K; Nigam, N; Saloura, V	1
Chen, L; Deng, X; Gao, F; Li, B; Li, L; Li, X; Liang, T; Pan, Y; Ren, Y; Wang, J; Yang, D; Yang, Y; Zhai, S; Zhang, S; Zhang, X; Zhao, J; Zheng, Y; Zhou, P	1
Fa, M; Jiang, Y; Lee, JH; Li, J; Li, X; Lu, Z; Wang, Y; Xia, Y; Yang, W; Zheng, Y	1
Azevedo, RB; Coelho, JPF; Diniz, CA; Dornelas, CA; Jamacaru, FVF; Juanes, CC; Santos, AMD	1
Chen, HZ; Guan, ZY; Guo, F; He, XD; Lin, Y; Liu, DP; Liu, LX; Qu, YY; Wang, SD; Wang, X; Wei, Y; Wu, XH; Xu, W; Yang, C; Yao, CF; Zhang, YK; Zhao, J; Zhao, SM; Zhou, KQ	1
Chen, R; Deng, R; Hou, G; Jiang, B; Wang, Y; Xu, M; Yu, J; Yuan, H; Zhang, H; Zhao, X	1
Bulic, M; Dupéré-Richer, D; Ezponda, T; Huang, X; Keats, J; Kelleher, N; Licht, JD; Maji, S; Nabet, B; Occhionorelli, M; Oyer, J; Patel, T; Popovic, R; Riva, A; Shah, MY; Small, EC; Tonon, G; Varghese, N; Will, CM; Zheng, Y	1
Adépo, JA; Dano, SD; Diakité, A; Manda, P; Ngbé, JV; Tigori Sangaré, B	1
Chiang, YC; Chowdhury, P; Davis, IJ; de Cubas, AA; Dere, R; Fahey, CC; Karki, M; Khan, A; Mason, FM; Ohi, R; Park, IY; Parker, JS; Powell, RT; Rathmell, WK; Shuster, CB; Sohn, BH; Strahl, BD; Terzo, EA; Tripathi, DN; Tsai, YS; Walker, CL	1
Andrews, CA; Chan, MP; Kahana, A; Rao, RC	1
An, S; Huang, G; Jia, W; Liu, J; Shen, M; Shi, L; Yan, H; Zhang, R; Zhao, L	1
Bassik, MC; Caporicci, M; Carlson, SM; Elias, JE; Francis, JW; Fuentes, ME; Gozani, O; Hausmann, S; Hulea, L; Kim, MP; Li, A; Liu, S; Lofgren, SM; Lu, J; Maitra, A; Mazur, PK; Nguyen, ND; Pillai, R; Porco, JA; Song, J; Tandoc, K; Topisirovic, I; Van Rechem, C; Wang, H; Wistuba, II	1
Cai, Z; Chen, TY; Gao, Y; Han, F; Hou, Z; Hsu, CC; Hu, J; Jin, G; Lan, J; Lee, MG; Li, H; Lin, HK; Long, J; Sun, L; Wang, G; Wang, YH; Xu, C; Yang, SC; Zhang, W	1
Bechet, D; Belle, J; Cagnone, G; Chen, CCL; Chen, H; Cheung, WA; De Jay, N; Deshmukh, S; Ellezam, B; Faury, D; Garcia, BA; Harutyunyan, AS; Hu, B; Jabado, N; Jain, SU; Kleinman, CL; Krug, B; Lewis, PW; Li, R; Lu, C; Majewski, J; Marchione, DM; McConechy, MK; Mikael, LG; Mohammadnia, A; Montpetit, A; Nikbakht, H; Papillon-Cavanagh, S; Pastinen, T; Pathania, M; Salomoni, P; Weil, AG; Zeinieh, M	1
Bardwell, VJ; Gearhart, MD; Gregory, G; Johnstone, RW; Kats, LM; Kelly, MJ; Li, J; Rogers, AJ; So, J; Vervoort, SJ; Zethoven, M	1
Liu, M; Liu, W; Wang, W; Zhang, J	1
Guo, J; Wei, W	1
Assenov, Y; Federico, A; Gebhardt, C; Granados, K; Hüser, L; Larribère, L; Lipka, DB; Novak, D; Orouji, E; Plass, C; Sachindra, S; Umansky, V; Utikal, J	1
Bonini, M; Brien, JO; Dean, AE; Gao, Y; Gius, D; Hart, R; Horikoshi, N; Jiang, H; Kieffer, MB; Liu, G; Park, SH; Quan, S; Satchell, KJF; Stauffer, ME; Tran, EL; Zhu, Y; Zou, X	1
Fan, M; Shi, X	1
Dong, H; Sun, B; Wang, Y; Zhang, J; Zhang, Q	1
Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y	1
Beland, FA; de Conti, A; Heidor, R; Koturbash, I; Kuroiwa-Trzmielina, J; Moreno, FS; Ong, TP; Pogribny, IP; Tryndyak, V	1
Beuch, S; Reuter, G; Rudolph, T	1
Li, Y; Liu, C; Xu, W; Zhao, S	1
Guan, KL; Jiang, Y; Lei, QY; Li, FL; Li, TT; Lv, L; Sasaki, N; Wang, W; Xiong, Y; Xu, YP; Zhao, D; Zhou, X	1
Bradner, JE; Chen, LF; Qi, J; Wu, X; Xiao, G	1
Atomi, Y; Hamamoto, R; Ibrahim, R; Kogure, M; Nakamura, Y; Piao, L; Saloura, V; Sone, K; Sugiyama, M; Takawa, M; Tsunoda, T; Ueda, K	1
Cavalcanti, BC; Dornelas, CA; Furtado, FN; Jamacaru, FV; Juanes, Cde C; Magalhães, HI; Melo, Nde O; Moraes, MO	1
Chen, J; Fu, Y; Li, C; Pang, B; Shen, K; Zhao, J	1
Goyama, S; Huang, G; Kurokawa, M; Mulloy, JC	1
Chen, C; Chen, Q; Chen, R; Deng, R; Dou, J; Huang, J; Jin, H; Wang, Y; Xu, M; Yu, J; Zhang, H; Zhao, X; Zhu, C	1
Honda, T; Kawamura, M; Sugimura, H; Susumu, H; Tanno, Y; Watanabe, Y	1
Armstrong, SA; Chen, S; Deshpande, AJ; Garcia, BA; Gozani, O; Krajewski, K; Patel, DJ; Sidoli, S; Strahl, BD; Wilkinson, AW; Yang, Z	1
Kaypee, S; Kundu, TK; Mukherjee, D; Sethi, G; Shanmugam, MK; Sudarshan, D	1
Cai, J; Cai, R; Cao, Y; Chen, FL; Cheng, J; Mu, J; Wang, T; Zuo, Y	1
Chen, S; De Marco, V; Gamblin, SJ; Haire, LF; Justin, N; Martin, SR; Reinberg, D; Tarricone, C; Underwood, E; Walker, PA; Wilson, JR; Zhang, Y	1
Allis, CD; Andrulis, IL; Bechet, D; Chi, P; De Jay, N; Dickson, BC; Fahiminiyah, S; Garcia, BA; Grynspan, D; Hameed, M; Hoelper, D; Jabado, N; Jain, SU; Jani, KS; Lewis, PW; Lu, C; Lundgren, SM; Majewski, J; Molden, RC; Muir, TW; Murphy, D; Nadaf, J; Papillon-Cavanagh, S; Pawel, BR; Ran, L; Sawyer, SL; Thompson, CB; Turcotte, RE; Venneti, S; Wunder, JS	1
Bradley, EW; Bridge, JA; Chen, J; Chen, Y; Fang, D; Gan, H; Han, J; Ho, TH; Jin, L; Lee, JH; Oliveira, AM; Ordog, T; Riester, SM; Rubin, BP; Thibodeau, SN; van Wijnen, AJ; Wang, J; Wang, Z; Westendorf, JJ; Xu, RM; Yang, N; Zhang, H; Zhang, Z; Zhou, H	1
Bizet, M; Brenner, C; Calonne, E; Cartron, PF; Dedeurwaerder, S; Defrance, M; Deplus, R; Fuks, F; Josseaux, E; Luciani, J; Ndlovu, M; Putmans, P	1
Ding, X; Duan, Y; Gao, J; Huo, D; Liu, Z; Shan, L; Shang, Y; Shi, L; Su, D; Wang, Y; Wu, H; Xuan, C; Ye, Z; Zhang, K; Zhou, X	1
Adam, A; Büttner, R; Dietlein, F; Ermolaeva, MA; Fernández-Majada, V; Komander, D; Pasparakis, M; Schell, M; Schumacher, B; Thomas, RK; Welz, PS	1
Azevedo, RB; Coelho, JP; Dornelas, CA; Jamacaru, FV; Juanes, CC; Melo, NO; Santos, AM	1
Dwane, L; Gallagher, WM; Ní Chonghaile, T; O'Connor, DP	1
Chou, PC; Han, F; Huang, CY; Jin, G; Li, B; Lin, HK; Logothetis, C; Long, J; Pan, BS; Rezaeian, AH; Tsai, CH; Tsai, FJ; Wang, CY; Xu, X; Zhang, A; Zhang, X	1

Reviews

11 review(s) available for lysine and Carcinogenesis

Article	Year
Molecular mechanisms in governing genomic stability and tumor suppression by the SETD2 H3K36 methyltransferase. The international journal of biochemistry & cell biology, 2022, Volume: 144 Topics: Animals; Carcinogenesis; Chromatin; Genomic Instability; Histones; Humans; Lysine; Mammals; Methylation; Neoplasms	2022
Oncometabolites drive tumorigenesis by enhancing protein acylation: from chromosomal remodelling to nonhistone modification. Journal of experimental & clinical cancer research : CR, 2022, Apr-15, Volume: 41, Issue:1 Topics: Acetylation; Acylation; Carcinogenesis; Histones; Humans; Lysine; Protein Processing, Post-Translational	2022
The role of lysine-specific demethylase 6A (KDM6A) in tumorigenesis and its therapeutic potentials in cancer therapy. Bioorganic chemistry, 2023, Volume: 133 Topics: Carcinogenesis; Histone Demethylases; Histones; Humans; Lysine; Neoplasms	2023
Complex functions of Gcn5 and Pcaf in development and disease. Biochimica et biophysica acta. Gene regulatory mechanisms, 2021, Volume: 1864, Issue:2 Topics: Acetylation; Adaptive Immunity; Animals; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Embryonic Development; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Immunity, Innate; Lysine; Mice; Mice, Transgenic; Mutation; Neoplasms; p300-CBP Transcription Factors	2021
Histone Methyltransferase SETDB1: A Common Denominator of Tumorigenesis with Therapeutic Potential. Cancer research, 2021, 02-01, Volume: 81, Issue:3 Topics: Carcinogenesis; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic	2021
SMYD3: a regulator of epigenetic and signaling pathways in cancer. Clinical epigenetics, 2021, 02-26, Volume: 13, Issue:1 Topics: Carcinogenesis; Chromatin; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Prognosis; Protein Processing, Post-Translational; Signal Transduction	2021
Lysine-specific histone demethylase LSD1 and the dynamic control of chromatin. Biological chemistry, 2013, Volume: 394, Issue:8 Topics: Animals; Carcinogenesis; Cell Cycle; Chromatin; Drosophila; Drosophila Proteins; Gene Silencing; Histone Demethylases; Humans; Lysine; Oxidoreductases, N-Demethylating; Schizosaccharomyces; Schizosaccharomyces pombe Proteins	2013
Protein lysine acetylation guards metabolic homeostasis to fight against cancer. Oncogene, 2014, May-01, Volume: 33, Issue:18 Topics: Acetylation; Carcinogenesis; Genes, Neoplasm; Homeostasis; Humans; Lysine; Mitochondria; Neoplasms; Sirtuins	2014
Posttranslational modifications of RUNX1 as potential anticancer targets. Oncogene, 2015, Volume: 34, Issue:27 Topics: Animals; Antineoplastic Agents; Base Sequence; Carcinogenesis; Core Binding Factor Alpha 2 Subunit; Hematologic Neoplasms; Humans; Lysine; Molecular Sequence Data; Molecular Targeted Therapy; Protein Processing, Post-Translational; Tyrosine	2015
Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics. Pharmacology & therapeutics, 2016, Volume: 162 Topics: Acetylation; Animals; Antineoplastic Agents; Carcinogenesis; Humans; Lysine; Lysine Acetyltransferases; Neoplasms	2016
The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways. The Journal of biological chemistry, 2017, 03-03, Volume: 292, Issue:9 Topics: Animals; Carcinogenesis; Catalysis; Fanconi Anemia; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Lysine; Neoplasms; NF-kappa B; Oncogenes; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Ubiquitin; Ubiquitination	2017

Other Studies

72 other study(ies) available for lysine and Carcinogenesis

Article	Year
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination. Nature cell biology, 2021, Volume: 23, Issue:9 Topics: Carcinogenesis; Deubiquitinating Enzyme CYLD; DNA-Binding Proteins; Genes, Tumor Suppressor; Humans; Lysine; MAP Kinase Signaling System; Phosphorylation; Polyubiquitin; Signal Transduction; Ubiquitin	2021
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53. Cell death & disease, 2021, 10-14, Volume: 12, Issue:10 Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Protein Domains; Protein Stability; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Treatment Outcome; Tripartite Motif Proteins; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination	2021
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer. International journal of molecular sciences, 2021, 12-27, Volume: 23, Issue:1 Topics: Animals; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Demethylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Histones; Lung Neoplasms; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Transcription Factors	2021
Genome-wide analysis of DNaseI hypersensitivity unveils open chromatin associated with histone H3 modifications after areca nut with lime exposure. Mutagenesis, 2022, 10-26, Volume: 37, Issue:3-4 Topics: Acetylation; Animals; Areca; Carcinogenesis; Chromatin; Histones; Lysine; Mice; Nuts; Plant Extracts; Securin	2022
JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis. Journal of hematology & oncology, 2022, 11-04, Volume: 15, Issue:1 Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cholesterol; Humans; Interleukin-6; Liver Neoplasms; Lysine; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease	2022
KDM6B promotes gastric carcinogenesis and metastasis via upregulation of CXCR4 expression. Cell death & disease, 2022, 12-23, Volume: 13, Issue:12 Topics: Carcinogenesis; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Receptors, CXCR4; Stomach Neoplasms; Transcriptional Activation; Up-Regulation	2022
Kawain Inhibits Urinary Bladder Carcinogenesis through Epigenetic Inhibition of LSD1 and Upregulation of H3K4 Methylation. Biomolecules, 2023, 03-13, Volume: 13, Issue:3 Topics: Animals; Carcinogenesis; Epigenesis, Genetic; Histone Demethylases; Humans; Lysine; Mice; Up-Regulation; Urinary Bladder; Urinary Bladder Neoplasms	2023
NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism-mediated cancer radiotherapy. Cell reports, 2023, 10-31, Volume: 42, Issue:10 Topics: Carcinogenesis; Fatty Acids; Histone-Lysine N-Methyltransferase; Humans; Lysine; Neoplasms; Repressor Proteins; Sirtuin 1	2023
Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry. Bioscience reports, 2023, 10-31, Volume: 43, Issue:10 Topics: Carcinogenesis; Cell Cycle; Cell Division; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine	2023
SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A. JCI insight, 2023, Oct-23, Volume: 8, Issue:20 Topics: Carcinogenesis; Cell Transformation, Neoplastic; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Matrix Metalloproteinase 1; Methylation; Prostatic Neoplasms	2023
STUB1 suppresseses tumorigenesis and chemoresistance through antagonizing YAP1 signaling. Cancer science, 2019, Volume: 110, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Mice; Neoplasm Transplantation; Phosphoproteins; Protein Stability; Proteolysis; Signal Transduction; Stomach Neoplasms; Transcription Factors; Ubiquitin-Protein Ligases; Ubiquitination; YAP-Signaling Proteins	2019
Activation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway. Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1 Topics: Acetylation; Adult; Anion Exchange Protein 1, Erythrocyte; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Interleukin-8; Lysine; Middle Aged; Neoplasm Invasiveness; NF-kappa B; RNA, Long Noncoding; Signal Transduction; Transcriptional Activation; Up-Regulation	2019
The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity. Cell reports, 2019, 10-01, Volume: 29, Issue:1 Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Carcinogenesis; Cell Line, Tumor; DNA Damage; Endopeptidases; Female; HSP70 Heat-Shock Proteins; Humans; Lysine; MCF-7 Cells; Mice; NEDD8 Protein; Ubiquitin	2019
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. The Journal of experimental medicine, 2020, 02-03, Volume: 217, Issue:2 Topics: Acetylcysteine; Adoptive Transfer; Animals; Carcinogenesis; Cell Polarity; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myeloid Cells; Myeloid-Derived Suppressor Cells; Reactive Oxygen Species; Signal Transduction; Transfection	2020
TAF1 plays a critical role in AML1-ETO driven leukemogenesis. Nature communications, 2019, 10-29, Volume: 10, Issue:1 Topics: Acetylation; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Chromatin; Core Binding Factor Alpha 2 Subunit; Gene Expression Regulation, Leukemic; Histone Acetyltransferases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice, Inbred C57BL; Myeloid Cells; Oncogene Proteins, Fusion; Protein Binding; Protein Domains; RUNX1 Translocation Partner 1 Protein; TATA-Binding Protein Associated Factors; Transcription Factor TFIID	2019
The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway. EBioMedicine, 2019, Volume: 49 Topics: Activin Receptors, Type I; ATP-Binding Cassette Transporters; Bone Morphogenetic Protein 6; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Humans; Lysine; Models, Biological; Neoplastic Stem Cells; Polyubiquitin; Prognosis; Proteasome Endopeptidase Complex; Protein Binding; Protein Stability; Signal Transduction; Trans-Activators; Ubiquitin-Protein Ligases; Ubiquitination	2019
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis. Cell reports, 2019, 11-05, Volume: 29, Issue:6 Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Databases, Genetic; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational	2019
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2020, Feb-25, Volume: 36, Issue:2 Topics: Carcinogenesis; Cell Transformation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Oncogenes	2020
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. The Journal of experimental medicine, 2020, 05-04, Volume: 217, Issue:5 Topics: Acetylation; Aged; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Disease Progression; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Interferons; Lysine; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Middle Aged; Neoplastic Stem Cells; Promoter Regions, Genetic; STAT1 Transcription Factor; Up-Regulation	2020
SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells. Molecular oncology, 2020, Volume: 14, Issue:9 Topics: Animals; Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Nude; MicroRNAs; Mutation; Neoplasms; Protein Binding; RNA-Binding Proteins; Signal Transduction; Stress, Physiological; Sumoylation; Uridine	2020
LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter. Cell death & disease, 2020, 05-04, Volume: 11, Issue:5 Topics: Carcinogenesis; Cell Line; Class Ib Phosphatidylinositol 3-Kinase; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; Retinoblastoma; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic	2020
The Ras-ERK1/2 signaling pathway regulates H3K9ac through PCAF to promote the development of pancreatic cancer. Life sciences, 2020, Sep-01, Volume: 256 Topics: Acetylation; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase 1; Histones; Humans; Lysine; MAP Kinase Signaling System; p300-CBP Transcription Factors; Pancreatic Neoplasms; Phenotype; Proteolysis; Proto-Oncogene Proteins c-mdm2; ras Proteins; Signal Transduction; Transcription, Genetic	2020
FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1. Cell communication and signaling : CCS, 2020, 06-23, Volume: 18, Issue:1 Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; F-Box Proteins; Gene Expression Regulation, Neoplastic; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Liver Neoplasms; Lysine; Mice, Inbred BALB C; Mice, Nude; Protein Stability; Proto-Oncogene Proteins c-myc; RNA, Messenger; Transcription, Genetic; Ubiquitination	2020
NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma. Cell reports, 2020, 06-23, Volume: 31, Issue:12 Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Enhancer of Zeste Homolog 2 Protein; Hedgehog Proteins; Histones; Humans; Lysine; Medulloblastoma; Methylation; Mice; Nerve Tissue Proteins; Neurons; Patched-1 Receptor; Signal Transduction; Single-Cell Analysis	2020
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration. Cell research, 2020, Volume: 30, Issue:11 Topics: Aging; Animals; Carcinogenesis; CCAAT-Enhancer-Binding Proteins; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA Replication; Genome, Human; HeLa Cells; Histones; Humans; Inheritance Patterns; Kinetics; Lysine; Mice; Mitosis; Mouse Embryonic Stem Cells; Nucleosomes; Proliferating Cell Nuclear Antigen; Protein Binding; Protein Domains; Ubiquitin-Protein Ligases	2020
E6 hijacks KDM5C/lnc_000231/miR-497-5p/CCNE1 axis to promote cervical cancer progression. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:19 Topics: Acetylation; Animals; Base Sequence; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Oncogene Proteins; Oncogene Proteins, Viral; Promoter Regions, Genetic; Protein Stability; RNA, Long Noncoding; Tumor Stem Cell Assay; Up-Regulation; Uterine Cervical Neoplasms	2020
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2. Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20 Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms	2020
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level. Cell communication and signaling : CCS, 2020, 10-27, Volume: 18, Issue:1 Topics: Animals; Carcinogenesis; CDX2 Transcription Factor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multivariate Analysis; Nuclear Proteins; Promoter Regions, Genetic; Repressor Proteins; Survival Analysis; Up-Regulation; Wnt Signaling Pathway	2020
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell, 2020, 12-10, Volume: 183, Issue:6 Topics: Animals; Astrocytes; Brain Neoplasms; Carcinogenesis; Cell Lineage; Cellular Reprogramming; Chromatin; Embryo, Mammalian; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Histones; Interneurons; Lysine; Mice, Inbred C57BL; Models, Biological; Mutation; Neoplasm Grading; Neural Stem Cells; Oligodendroglia; Promoter Regions, Genetic; Prosencephalon; Receptor, Platelet-Derived Growth Factor alpha; Transcription, Genetic; Transcriptome	2020
mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression. Genes & development, 2021, 01-01, Volume: 35, Issue:1-2 Topics: Acetylation; Animals; Carcinogenesis; Cell Cycle Checkpoints; Embryo, Mammalian; Lysine; Mice; Mutation; Neoplasms; Proto-Oncogene Proteins c-mdm2; Sirolimus; Survival Analysis; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2021
Long noncoding RNA ATB promotes ovarian cancer tumorigenesis by mediating histone H3 lysine 27 trimethylation through binding to EZH2. Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:1 Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Protein Binding; RNA, Long Noncoding; Treatment Outcome	2021
RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nature communications, 2021, 02-16, Volume: 12, Issue:1 Topics: Animals; Arginine; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Female; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Lysine; Mechanistic Target of Rapamycin Complex 1; Mice, Nude; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Ubiquitin-Protein Ligases; Ubiquitination	2021
Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation. Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-02, Volume: 118, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Carcinogenesis; Cell Line; Chromatin; CRISPR-Cas Systems; Cytarabine; Decitabine; Epigenesis, Genetic; Gene Editing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methylation; Mice; Mutation; Neoplasm Proteins; Neoplasms; Phenotype; Protein Isoforms; Protein Processing, Post-Translational; Repressor Proteins; Transcriptome	2021
Histone demethylase KDM4A plays an oncogenic role in nasopharyngeal carcinoma by promoting cell migration and invasion. Experimental & molecular medicine, 2021, Volume: 53, Issue:8 Topics: Adult; Aged; Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Nude; Middle Aged; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Up-Regulation; Young Adult	2021
RNF8 mediates histone H3 ubiquitylation and promotes glycolysis and tumorigenesis. The Journal of experimental medicine, 2017, 06-05, Volume: 214, Issue:6 Topics: Carcinogenesis; Cell Line, Tumor; Cyclin D1; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression Regulation; Glycolysis; Histones; Humans; Lysine; Models, Biological; Nucleosomes; Phosphothreonine; Promoter Regions, Genetic; Protein Domains; Proteolysis; Proto-Oncogene Proteins c-myc; Ubiquitin-Protein Ligases; Ubiquitination	2017
Transitional metaplasia in intestinal epithelium of rats submitted to intestinal cystoplasty and treatment with L -lysine. Acta cirurgica brasileira, 2017, Volume: 32, Issue:4 Topics: Animals; Carcinogenesis; Disease Models, Animal; Female; Intestinal Mucosa; Lysine; Metaplasia; Rats; Urinary Bladder; Urinary Diversion	2017
Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients. Nature communications, 2017, 09-06, Volume: 8, Issue:1 Topics: Acetylation; Amino Acids, Branched-Chain; Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Enoyl-CoA Hydratase; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Hep G2 Cells; Humans; Lysine; Male; Mice; Mice, Knockout; Neoplasm Transplantation; Recombinant Proteins; Signal Transduction; Sirtuin 3; TOR Serine-Threonine Kinases; Ubiquitin	2017
SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis. Molecular cancer, 2017, 10-11, Volume: 16, Issue:1 Topics: Base Composition; Carcinogenesis; Cell Line, Tumor; Disease Progression; Humans; Hydrogen Peroxide; Hypoxia; Lysine; MicroRNAs; Models, Biological; Nucleic Acid Conformation; Protein Binding; Protein Transport; RNA-Binding Proteins; SUMO-1 Protein; Sumoylation; Terminal Repeat Sequences; Trans-Activators	2017
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition. Cell reports, 2017, Oct-17, Volume: 21, Issue:3 Topics: Animals; Carcinogenesis; Cell Adhesion; Cell Dedifferentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clone Cells; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Indazoles; Interferon Regulatory Factors; Lysine; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Mutation; Nuclear Proteins; Phenotype; Pyridones; Transcription, Genetic	2017
Study of aflatoxicosis reduction: effect of Alchornea cordifolia on biomarkers in an aflatoxin B1 exposed rats. Drug and chemical toxicology, 2019, Volume: 42, Issue:3 Topics: Aflatoxin B1; Aflatoxin M1; Animals; Antioxidants; Biomarkers; Carcinogenesis; Dose-Response Relationship, Drug; Euphorbiaceae; Lysine; Male; Plant Extracts; Plant Leaves; Rats, Wistar; Toxicity Tests, Acute	2019
Cancer research, 2018, 06-15, Volume: 78, Issue:12 Topics: Animals; Carcinogenesis; Carcinoma, Renal Cell; Cell Line, Tumor; Chromosomes, Human, Pair 3; Fibroblasts; Gene Knockdown Techniques; Genomic Instability; Haploinsufficiency; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney Neoplasms; Kidney Tubules, Proximal; Lysine; Methylation; Mice; Micronuclei, Chromosome-Defective; Microtubules	2018
Epigenetic markers in basal cell carcinoma: universal themes in oncogenesis and tumor stratification? - a short report. Cellular oncology (Dordrecht), 2018, Volume: 41, Issue:6 Topics: 5-Methylcytosine; Carcinogenesis; Carcinoma, Basal Cell; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Skin Neoplasms	2018
SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer. Molecular oncology, 2019, Volume: 13, Issue:2 Topics: Acetylation; Amino Acid Sequence; Animals; Autophagy; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Colorectal Neoplasms; Female; HEK293 Cells; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lysine; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Prognosis; Protein Binding; Sirtuins	2019
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Cell, 2019, 01-24, Volume: 176, Issue:3 Topics: Adult; Aged; Animals; Carcinogenesis; Cell Line; Cell Transformation, Neoplastic; Female; HEK293 Cells; Heterografts; Humans; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pancreatic Neoplasms; Peptide Elongation Factor 1; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Signal Transduction	2019
SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis. Nature cell biology, 2019, Volume: 21, Issue:2 Topics: A549 Cells; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Female; HEK293 Cells; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; NIH 3T3 Cells; Protein Methyltransferases; Proto-Oncogene Proteins c-akt; Transplantation, Heterologous; Ubiquitination	2019
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nature communications, 2019, 03-19, Volume: 10, Issue:1 Topics: Adolescent; Aged; Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Child; Chromatin; CpG Islands; CRISPR-Cas Systems; DNA Methylation; Epigenesis, Genetic; Female; Gene Editing; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Histone Code; Histones; Humans; Lysine; Male; Methionine; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neurogenesis; Polycomb Repressive Complex 2; Xenograft Model Antitumor Assays	2019
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis. Nature communications, 2019, 03-22, Volume: 10, Issue:1 Topics: Animals; Carcinogenesis; Cell Differentiation; Cell Proliferation; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histones; Homeodomain Proteins; Leukemia; Lysine; Mice, Inbred C57BL; Mutation; Myeloid Cells; Polycomb Repressive Complex 1; Proto-Oncogene Proteins p21(ras); Repressor Proteins; Transcription Factors; Transcription, Genetic; Ubiquitination	2019
Ras-ERK1/2 signalling promotes the development of osteosarcoma through regulation of H4K12ac through HAT1. Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1 Topics: Acetylation; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Activation; Histone Acetyltransferases; Histones; Humans; Lysine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteosarcoma; Proteolysis; Proto-Oncogene Proteins c-mdm2; ras Proteins; Transcription, Genetic	2019
Fine-tuning AKT kinase activity through direct lysine methylation. Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:9 Topics: Animals; Carcinogenesis; Histone-Lysine N-Methyltransferase; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt	2019
Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target. International journal of cancer, 2019, 12-15, Volume: 145, Issue:12 Topics: Animals; Carcinogenesis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Melanoma; Mice; Mice, Inbred NOD; Mice, SCID	2019
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter. Nature communications, 2019, 06-03, Volume: 10, Issue:1 Topics: Acetylation; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Drug Resistance, Neoplasm; Humans; In Vitro Techniques; Lysine; MCF-7 Cells; Mice; Mutation; Neoplasm Transplantation; Peroxidase; Protein Structure, Quaternary; Reactive Oxygen Species; Superoxide Dismutase; Tamoxifen; Tumor Suppressor Proteins	2019
Tip60-dependent acetylation of KDM2B promotes osteosarcoma carcinogenesis. Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:9 Topics: Acetylation; Animals; Carcinogenesis; Cell Line, Tumor; F-Box Proteins; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Lysine Acetyltransferase 5; Methylation; Mice; Osteosarcoma; Promoter Regions, Genetic; Protein Processing, Post-Translational	2019
p300 Acetylates JHDM1A to inhibit osteosarcoma carcinogenesis. Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1 Topics: Acetylation; Animals; Apoptosis Regulatory Proteins; Carcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; E1A-Associated p300 Protein; F-Box Proteins; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Nucleosomes; Osteosarcoma; Proto-Oncogene Proteins; Transcription, Genetic	2019
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo. Cancer science, 2013, Volume: 104, Issue:7 Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation	2013
The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. Carcinogenesis, 2013, Volume: 34, Issue:8 Topics: Acetylation; Animals; Apoptosis; Butyric Acid; Carcinogenesis; Hepatocytes; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Liver Neoplasms, Experimental; Lysine; Male; Precancerous Conditions; Prodrugs; Random Allocation; Rats; Rats, Wistar; Signal Transduction; Triglycerides; Tumor Suppressor Protein p53; Up-Regulation	2013
Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. Molecular cell, 2013, Nov-07, Volume: 52, Issue:3 Topics: Acetylation; Alternative Splicing; Carcinogenesis; Carrier Proteins; Cell Proliferation; Fructosediphosphates; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lysine; Membrane Proteins; p300-CBP Transcription Factors; Thyroid Hormone-Binding Proteins; Thyroid Hormones	2013
Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling. The Journal of biological chemistry, 2013, Dec-13, Volume: 288, Issue:50 Topics: Acetylation; Animals; Azepines; Carcinogenesis; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Lysine; Mice; Nuclear Proteins; Signal Transduction; Transcription Factor RelA; Transcription Factors; Triazoles	2013
The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination. Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:11 Topics: Carcinogenesis; Cell Line; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; HeLa Cells; Histones; Humans; Lysine; MCF-7 Cells; Polycomb Repressive Complex 2; Transcription, Genetic; Ubiquitination	2013
Potential chemoprotective effects of green propolis, L-lysine and celecoxib on bone marrow cells and peripheral blood lymphocytes of Wistar rats subjected to bladder chemical carcinogenesis. Acta cirurgica brasileira, 2014, Volume: 29, Issue:7 Topics: Animals; Anticarcinogenic Agents; Bone Marrow Cells; Carcinogenesis; Carcinogenicity Tests; Celecoxib; Comet Assay; DNA Damage; Lymphocytes; Lysine; Micronucleus Tests; Propolis; Pyrazoles; Rats, Wistar; Reference Values; Reproducibility of Results; Sulfonamides; Time Factors; Urinary Bladder Neoplasms	2014
EZH2-induced H3K27me3 is associated with epigenetic repression of the ARHI tumor-suppressor gene in ovarian cancer. Cell biochemistry and biophysics, 2015, Volume: 71, Issue:1 Topics: Adenosine; Carcinogenesis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Female; Gene Knockdown Techniques; Histones; Humans; Lysine; Methylation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polycomb Repressive Complex 2; rho GTP-Binding Proteins; RNA, Small Interfering; Survival Analysis; Tumor Suppressor Proteins	2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic acids research, 2015, Sep-18, Volume: 43, Issue:16 Topics: Animals; Carcinogenesis; Cell Line; Cell Movement; Cells, Cultured; Humans; Lysine; Mice; Mice, Nude; MicroRNAs; Neoplasms; Phosphorylation; Protein Stability; RNA-Binding Proteins; SUMO-1 Protein; Sumoylation; Ubiquitination	2015
RETRACTED: The inner centromere-shugoshin network prevents chromosomal instability. Science (New York, N.Y.), 2015, 09-11, Volume: 349, Issue:6253 Topics: BRCA1 Protein; Carcinogenesis; Cell Cycle Proteins; Centromere; Chromatids; Chromatin; Chromosomal Instability; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Cohesins; HeLa Cells; Histones; Humans; Kinetochores; Lysine; Methylation; Microtubules; Retinoblastoma Protein	2015
The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Molecular cell, 2015, Oct-15, Volume: 60, Issue:2 Topics: Binding Sites; Carcinogenesis; Cell Line, Tumor; Chromatin; Crystallography, X-Ray; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydrogen Bonding; Leukocytes; Lysine; Methylation; Methyltransferases; Models, Molecular; Protein Binding; Protein Interaction Domains and Motifs; Signal Transduction; Transcription Factors	2015
A crucial role of SUMOylation in modulating Sirt6 deacetylation of H3 at lysine 56 and its tumor suppressive activity. Oncogene, 2016, 09-15, Volume: 35, Issue:37 Topics: A549 Cells; Acetylation; Carcinogenesis; Cell Proliferation; Genes, Tumor Suppressor; Histone Deacetylases; Humans; Lung Neoplasms; Lysine; Proto-Oncogene Proteins c-myc; Sirtuins; Sumoylation	2016
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2. Nature communications, 2016, 04-28, Volume: 7 Topics: Brain Neoplasms; Carcinogenesis; Catalytic Domain; Crystallography, X-Ray; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Lysine; Methylation; Models, Molecular; Mutation; Oncogenes; Polycomb Repressive Complex 2; Protein Binding; Protein Domains	2016
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science (New York, N.Y.), 2016, May-13, Volume: 352, Issue:6287 Topics: Animals; Bone Neoplasms; Carcinogenesis; Child, Preschool; Chondroblastoma; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methionine; Methylation; Methyltransferases; Mice; Mutation; Mutation, Missense; Neoplastic Stem Cells; Nucleosomes; Polycomb Repressive Complex 1; Sarcoma	2016
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science (New York, N.Y.), 2016, Jun-10, Volume: 352, Issue:6291 Topics: Amino Acid Substitution; Bone Neoplasms; Carcinogenesis; Chondroblastoma; Epigenesis, Genetic; Genes, Neoplasm; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Repressor Proteins	2016
The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent. Oncotarget, 2016, Sep-13, Volume: 7, Issue:37 Topics: Animals; Carcinogenesis; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; HeLa Cells; Histone Demethylases; Histones; Humans; Lysine; Mice; Neoplasms; NIH 3T3 Cells; Protein Binding; S Phase Cell Cycle Checkpoints	2016
Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5. Nature communications, 2016, 08-25, Volume: 7 Topics: Animals; Apoptosis; Biocatalysis; Breast Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Kinesins; Loss of Function Mutation; Lysine; MCF-7 Cells; Mice, Nude; Mitosis; Protein Binding; Protein Stability; Signal Transduction; Spindle Apparatus; Spindle Poles; Ubiquitin-Protein Ligases; Ubiquitination	2016
The tumour suppressor CYLD regulates the p53 DNA damage response. Nature communications, 2016, 08-26, Volume: 7 Topics: Animals; Apoptosis; Azoxymethane; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carcinogenesis; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Intestinal Neoplasms; Lysine; Male; Mice; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53; Ubiquitination	2016
Carcinogenesis in rats subjected to a new model ureterosigmoidostomy and treated with L-lysine. Acta cirurgica brasileira, 2016, Volume: 31, Issue:12 Topics: Aberrant Crypt Foci; Animals; Carcinogenesis; Colon, Sigmoid; Disease Models, Animal; Female; Intestinal Mucosa; Intestinal Neoplasms; Lysine; Rats; Rats, Wistar; Surgical Stomas; Ureterostomy; Urinary Bladder Neoplasms; Urinary Diversion; Urologic Neoplasms	2016
H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nature communications, 2017, 03-16, Volume: 8 Topics: Acetylation; Animals; Carcinogenesis; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose; HEK293 Cells; Histones; Humans; Lysine; Mice, Nude; Nedd4 Ubiquitin Protein Ligases; Transplantation, Heterologous; Ubiquitination	2017