Compounds > lysine
Page last updated: 2024-08-17

lysine and Cancer of Pancreas

lysine has been researched along with Cancer of Pancreas in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.38)18.7374
1990's0 (0.00)18.2507
2000's10 (21.28)29.6817
2010's26 (55.32)24.3611
2020's8 (17.02)2.80

Authors

AuthorsStudies
Brillouet, S; Chatelut, E; Courbon, F; Dierickx, L; Lambert, M1
Li, C; Lu, Y1
Chen, D; He, Q; He, X; Li, J; Li, M; Li, T; Liu, H; Liu, J; Tao, Y; Zang, S; Zhang, L1
Cheng, K; Fetse, J; Guo, Y; Hasan, MR; Jain, A; Lin, CY; Nakhjiri, M; Patel, P; Zhao, Z1
Dong, QZ; Guo, Y; Hu, BY; Qin, LX; Qin, ZY; Shen, KY; Wang, CQ; Wang, S; Wang, XF; Xue, M; Zheng, Y; Zhu, L1
Ge, Y; Jin, JY; Li, M; Li, XY; Li, YH; Li, YX; Song, SW; Tan, XD; Ye, J1
Churchill, M; Gu, W; Kon, N; Li, H; Manfredi, JJ; Mukherjee, S1
Casanova, AG; Lemonnier, N; Reynoird, N; Roth, GS1
Fujimura, K; Klemke, RL; Wang, H; Watson, F1
Colby, AH; Grinstaff, MW; Liu, K; Lu, C; Oberlies, NH; Pearce, C; Sabbatini, ME; Yang, D1
Bengtsson, E; Blixt, O; Danielsson, L; Jansson, B; Nodin, B; Nordin Fredrikson, G; Persson, N; Risinger, C; Welinder, C; Wendel, U1
Blasetti Fantauzzi, C; Cappello, P; de Latouliere, L; Iacobini, C; Ionta, V; Manni, I; Menini, S; Novelli, F; Pesce, C; Piaggio, G; Pugliese, G1
Bassik, MC; Caporicci, M; Carlson, SM; Elias, JE; Francis, JW; Fuentes, ME; Gozani, O; Hausmann, S; Hulea, L; Kim, MP; Li, A; Liu, S; Lofgren, SM; Lu, J; Maitra, A; Mazur, PK; Nguyen, ND; Pillai, R; Porco, JA; Song, J; Tandoc, K; Topisirovic, I; Van Rechem, C; Wang, H; Wistuba, II1
Chen, H; Cheng, Q; Huang, R; Li, S; Qian, Y; Shao, Z; Wang, H; Xiang, M; Xie, R; Xu, N; Xu, Q; Zhou, Z1
Andrade, N; Correia-Branco, A; Ferreira, AC; Martel, F; Silva, C; Soares, ML; Sonveaux, P; Stephenne, J1
Damen, E; Ehlert, JE; Feger, D; Heidemann-Dinger, C; Kubbutat, M; Leenders, R; Lenstra, DC; Mecinović, J; Müller, D; Müller, G; Schächtele, C; Trivarelli, F; van Bree, B; van de Sande, M; Wegert, A; Zijlmans, R1
Fang, W; Song, J; Sun, X; Zhan, J; Zhang, H; Zhang, J1
Dong, B; Guan, KL; Lei, QY; Liu, Y; Mo, Y; Wang, P; Xiong, Y; Xu, YH; Zhao, D; Zhou, X; Zou, SW1
Barbash, O; Butte, AJ; Dhanak, D; Garcia, BA; Gozani, O; Huddleston, M; Jansen, PW; Khatri, P; Kruger, RG; Liu, S; Mazur, PK; Reynoird, N; Sage, J; Tummino, PJ; Van Aller, GS; Vermeulen, M; Wilkinson, AW1
Bouvet, M; Fujimura, K; Kaushal, S; Kelber, JA; Klemke, RL; Lowy, AM; Metildi, C; Strnadel, J; Wright, T1
Colón-Bolea, P; Crespo, P1
Chen, Y; Huang, K; Li, J; Liang, J; Lin, Z; Qian, C; Wu, W; Zeng, L; Zhang, Q1
Chen, L; Cross, AJ; Duan, Z; Hollenbeck, A; Jiao, L; Kahle, L; Risch, A; Sinha, R; Stolzenberg-Solomon, R; Striker, G; Subar, AF; Vlassara, H; Zimmerman, TP1
Karnak, D; Lawrence, TS; Morgan, MA; Sun, Y; Tan, M; Zhang, Q1
Biancucci, M; Gius, D; Jiang, H; Kang, HJ; O'Callaghan, C; Park, SH; Principe, DR; Raparia, K; Satchell, KF; Song, HY; Vassilopoulos, A; Yan, Y1
Dirisala, A; Ikeda, S; Kataoka, K; Osada, K; Takeda, KM; Tockary, TA; Toh, K; Yamasaki, Y1
Allis, CD; Cook, RG; Frierson, HF; Fujita, M; Fukusato, T; Iizuka, M; Mizzen, CA; Smith, MM; Takahashi, Y1
Fischer, SM; Loo, JA; Matyska, MT; Pesek, JJ; Sana, TR1
Braunschweig, T; Büttner, R; Ellinger, J; Gütgemann, I; Höller, T; Koch, LK; Kremmer, E; Lüscher, B; Magerl, C1
Itaka, K; Kataoka, K; Kim, P; Morii, K; Osada, K; Yun, SH1
Hiki, S; Kano, MR; Kataoka, K; Koyama, H; Miyata, K; Miyazono, K; Nishiyama, N; Oba, M; Vachutinsky, Y1
Aguiar, M; Gygi, SP; Sliter, DA; Wojcikiewicz, RJ1
Chang, CW; Ding, H; Erogbogbo, F; Law, WC; Prasad, PN; Roy, I; Swihart, MT; Tien, CA; Yong, KT1
Allen, NE; Argüelles Suárez, MV; Barricarte, A; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Clavel-Chapelon, F; Crowe, FL; Dorronsoro, M; Drogan, D; Duell, EJ; Fedirko, V; Grote, VA; Huerta Castaño, JM; Jenab, M; Jeurnink, SM; Kaaks, R; Khaw, KT; Lagiou, P; Lindkvist, B; Lukanova, A; Mattiello, A; Nielsen, MR; Nieters, A; Overvad, K; Palli, D; Peeters, PH; Racine, A; Regner, S; Rohrmann, S; Romaguera, D; Roswall, N; Sánchez, MJ; Siddiq, A; Sieri, S; Sund, M; Teucher, B; Tjønneland, A; Trichopoulos, D; Trichopoulou, A; Tumino, R; Vineis, P; Wareham, N; Ye, W1
Akaike, M; Kameda, Y; Miyagi, Y; Morinaga, S; Nakamura, Y; Numata, M; Ohkawa, S; Shiozawa, M; Tamagawa, H; Watanabe, T; Yamamoto, N1
Avan, A; Cantore, M; Caponi, S; Cereda, S; Giovannetti, E; Mambrini, A; Milella, M; Pacetti, P; Peters, GJ; Reni, M; Vaccaro, V; Vasile, E1
FARAONI, H; FROMM, GA; HECKER, E; NAJENSON, H1
Bouterfa, H; Bushnell, D; Carlisle, T; Connolly, M; Kahn, D; Karwal, M; Madsen, M; Menda, Y; Miller, S; O'Dorisio, S; O'Dorisio, T; Ponto, J; Squires, S; Walkner, W1
Amidon, GL; Landowski, CP; Song, X; Vig, BS1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Abbruzzese, JL; Bondy, ML; Evans, DB; Hassan, MM; Jiao, L; Li, D1
Abbruzzese, JL; Adsay, NV; Albarracin, C; Bast, RC; Hortobagyi, GN; Hung, MC; Liu, J; Mills, GB; Wang, H; Wei, Y; Xia, W; Yu, D; Zhang, Z1
Goto, M; Hamada, T; Higashi, M; Nishida, Y; Nomoto, M; Tsutsumida, H; Yamada, N; Yonezawa, S1
Beuneu, C; Goldman, M; Verhasselt, V; Vosters, O1
Haas, OA; Muhr, D; Niederle, B; Scheuba, C; Schlegl, R; Vierhapper, H; Wagner, T; Weinhaeusel, A1
Amatruda, TT; Upton, GV1
Karuzina, NP; Timofeevskaia, EA1

Reviews

1 review(s) available for lysine and Cancer of Pancreas

ArticleYear
Lysine methylation in cancer: SMYD3-MAP3K2 teaches us new lessons in the Ras-ERK pathway.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2014, Volume: 36, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Protein Binding; Protein Kinase Inhibitors; Protein Phosphatase 2; Proto-Oncogene Proteins p21(ras); Signal Transduction

2014

Trials

2 trial(s) available for lysine and Cancer of Pancreas

ArticleYear
Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:1

    Topics: Aged; Cohort Studies; Databases, Factual; Diet; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Meat; Middle Aged; Normal Distribution; Pancreatic Neoplasms; Proportional Hazards Models; Prospective Studies; Risk; Sex Factors; Surveys and Questionnaires; United States

2015
Effects of intravenous amino acid administration with Y-90 DOTA-Phe1-Tyr3-Octreotide (SMT487[OctreoTher) treatment.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:1

    Topics: Adult; Aged; Amino Acids; Arginine; Carcinoid Tumor; Female; Humans; Infusions, Intravenous; Kidney; Lung Neoplasms; Lysine; Male; Meningioma; Middle Aged; Octreotide; Pancreatic Neoplasms; Radiopharmaceuticals; Yttrium Radioisotopes

2004

Other Studies

44 other study(ies) available for lysine and Cancer of Pancreas

ArticleYear
Comparison of Two Types of Amino Acid Solutions on
    Current radiopharmaceuticals, 2022, Volume: 15, Issue:2

    Topics: Arginine; Humans; Intestinal Neoplasms; Lysine; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Positron-Emission Tomography; Radionuclide Imaging; Radiopharmaceuticals; Stomach Neoplasms

2022
Incidental Findings of Coexisting Metastatic Pancreatic Cancer in Patients With Prostate Cancer on 18 F-Prostate-Specific Membrane Antigen PET/CT.
    Clinical nuclear medicine, 2022, Dec-01, Volume: 47, Issue:12

    Topics: Aged; Gallium Radioisotopes; Humans; Incidental Findings; Lysine; Male; Pancreatic Neoplasms; Positron Emission Tomography Computed Tomography; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Urea

2022
Spatially targeting and regulating tumor-associated macrophages using a raspberry-like micellar system sensitizes pancreatic cancer chemoimmunotherapy.
    Nanoscale, 2022, Sep-22, Volume: 14, Issue:36

    Topics: Cathepsin B; Cell Line, Tumor; Humans; Lysine; Macrophages; Micelles; Pancreatic Neoplasms; Peptides; Phosphatidylinositol 3-Kinases; Polyethylene Glycols; Tumor Microenvironment; Tumor-Associated Macrophages; Wortmannin

2022
Development of amino acid-modified biodegradable lipid nanoparticles for siRNA delivery.
    Acta biomaterialia, 2022, Volume: 154

    Topics: Amino Acids; Animals; Humans; Lipids; Lysine; Male; Mice; Nanoparticles; Pancreatic Neoplasms; Prostatic Neoplasms; RNA, Small Interfering

2022
Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression.
    Cell reports, 2023, 07-25, Volume: 42, Issue:7

    Topics: Glycolysis; Histones; Humans; Lysine; Pancreatic Neoplasms; Protein Processing, Post-Translational

2023
The Ras-ERK1/2 signaling pathway regulates H3K9ac through PCAF to promote the development of pancreatic cancer.
    Life sciences, 2020, Sep-01, Volume: 256

    Topics: Acetylation; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase 1; Histones; Humans; Lysine; MAP Kinase Signaling System; p300-CBP Transcription Factors; Pancreatic Neoplasms; Phenotype; Proteolysis; Proto-Oncogene Proteins c-mdm2; ras Proteins; Signal Transduction; Transcription, Genetic

2020
Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
    Cancer research, 2021, 02-15, Volume: 81, Issue:4

    Topics: Acetylation; Animals; Apoptosis; Carcinoma, Pancreatic Ductal; Cells, Cultured; DNA Damage; Genes, Tumor Suppressor; Lysine; Mice; Mice, Transgenic; Mutant Proteins; Mutation; Pancreatic Neoplasms; Protein Processing, Post-Translational; Protein Stability; Transcriptional Activation; Tumor Suppressor Protein p53

2021
Lysine methylation signaling in pancreatic cancer.
    Current opinion in oncology, 2018, Volume: 30, Issue:1

    Topics: Animals; Histone-Lysine N-Methyltransferase; Humans; Lysine; MAP Kinase Signaling System; Methylation; Pancreatic Neoplasms; Signal Transduction

2018
KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop.
    Cancer research, 2018, 03-15, Volume: 78, Issue:6

    Topics: Animals; Carcinoma, Pancreatic Ductal; Eukaryotic Translation Initiation Factor 5A; Feedback, Physiological; Female; Glutamine; GTP Phosphohydrolases; Humans; Lysine; Membrane Proteins; Mice, Nude; Pancreatic Neoplasms; Peptide Initiation Factors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); RNA-Binding Proteins; Signal Transduction; Xenograft Model Antitumor Assays

2018
Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells.
    BMC cancer, 2018, 02-06, Volume: 18, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gemcitabine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Indoles; Lysine; Methylation; Pancreatic Neoplasms

2018
A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer.
    PloS one, 2018, Volume: 13, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Atherosclerosis; Epitope Mapping; Female; Glycation End Products, Advanced; Humans; Lysine; Mice; Mice, Inbred BALB C; Pancreatic Neoplasms; Protein Array Analysis

2018
The advanced glycation end-product N
    The Journal of pathology, 2018, Volume: 245, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Diabetes Complications; Disease Models, Animal; Disease Progression; Genes, ras; Humans; Lysine; Mice, Inbred C57BL; Mice, Transgenic; Pancreatic Neoplasms; Peptides; Receptor for Advanced Glycation End Products; Risk Factors; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2018
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
    Cell, 2019, 01-24, Volume: 176, Issue:3

    Topics: Adult; Aged; Animals; Carcinogenesis; Cell Line; Cell Transformation, Neoplastic; Female; HEK293 Cells; Heterografts; Humans; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pancreatic Neoplasms; Peptide Elongation Factor 1; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Signal Transduction

2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
    Molecular oncology, 2019, Volume: 13, Issue:4

    Topics: Adenocarcinoma; Adenosine; Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Conditioned; Dendritic Cells; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Pancreatic Neoplasms; Phenylurea Compounds; Signal Transduction; Thiostrepton; Wnt-5a Protein

2019
Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.
    European journal of pharmacology, 2019, Sep-15, Volume: 859

    Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Glucose; Humans; Lactic Acid; Lysine; Pancreatic Neoplasms; Polyphenols

2019
Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2.
    Bioorganic & medicinal chemistry letters, 2019, 09-01, Volume: 29, Issue:17

    Topics: Binding Sites; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Molecular Docking Simulation; Pancreatic Neoplasms; Point Mutation; Quinazolines; Structure-Activity Relationship

2019
Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma.
    Frontiers of medicine, 2020, Volume: 14, Issue:1

    Topics: Acetylation; Adult; Aged; Aged, 80 and over; Carcinoma, Pancreatic Ductal; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Protein Processing, Post-Translational

2020
Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer.
    Cancer cell, 2013, Apr-15, Volume: 23, Issue:4

    Topics: Acetylation; Animals; Autophagy; Cell Growth Processes; Cell Movement; Down-Regulation; Gene Knockdown Techniques; HeLa Cells; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lysine; Mice; Mice, Nude; Pancreatic Neoplasms; Sirtuin 2; Transfection; Transplantation, Heterologous

2013
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
    Nature, 2014, Jun-12, Volume: 510, Issue:7504

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Pancreatic Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins A-raf; Signal Transduction

2014
A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer.
    Cancer research, 2014, Nov-15, Volume: 74, Issue:22

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Ciclopirox; Deoxycytidine; Eukaryotic Translation Initiation Factor 5A; Female; Gemcitabine; Humans; Lysine; Mice; Pancreatic Neoplasms; Peptide Initiation Factors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyridones; ras Proteins; RNA-Binding Proteins

2014
Effective suppression of the Kirsten rat sarcoma viral oncogene in pancreatic tumor cells via targeted small interfering RNA delivery using nanoparticles.
    Pancreas, 2015, Volume: 44, Issue:2

    Topics: Animals; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Therapy; Humans; Hyaluronan Receptors; Lysine; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanomedicine; Nanoparticles; Neoplasm Invasiveness; Pancreatic Neoplasms; Polyethylene Glycols; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA Interference; RNA, Small Interfering; Single-Chain Antibodies; Time Factors; Transfection; Tumor Burden; U937 Cells; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2015
FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.
    Molecular cell, 2016, Feb-04, Volume: 61, Issue:3

    Topics: Amino Acid Sequence; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cyclopentanes; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; HCT116 Cells; Humans; Lysine; Mice, Knockout; Molecular Sequence Data; Nuclear Proteins; Pancreatic Neoplasms; Phosphorylation; Polyubiquitin; Protein Processing, Post-Translational; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; RNA Interference; Time Factors; Transfection; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination; Ubiquitins

2016
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Acetylation; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HCT116 Cells; HEK293 Cells; Humans; Lung Neoplasms; Lysine; Male; Mice; Mice, Knockout; Mice, Nude; Mutation; NIH 3T3 Cells; Pancreatic Neoplasms; Phenotype; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sirtuin 2; Time Factors; Tumor Burden

2016
Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(l-lysine) block copolymers as systemic gene delivery carrier.
    Biomaterials, 2017, Volume: 126

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Blood Circulation; Cell Line, Tumor; Cross-Linking Reagents; DNA; DNA Packaging; Gene Transfer Techniques; Humans; Lysine; Mice, Inbred BALB C; Micelles; Pancreatic Neoplasms; Plasmids; Polyethylene Glycols; Shear Strength; Transfection

2017
Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers.
    Gene, 2009, May-01, Volume: 436, Issue:1-2

    Topics: Acetylation; Binding Sites; Blotting, Western; Breast Neoplasms; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histones; Humans; Immunohistochemistry; Kidney Neoplasms; Lysine; Male; Neoplasms; Nucleosomes; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Recombinant Proteins; Tissue Array Analysis; Urinary Bladder Neoplasms

2009
Analysis of hydrophilic metabolites in physiological fluids by HPLC-MS using a silica hydride-based stationary phase.
    Journal of separation science, 2009, Volume: 32, Issue:13

    Topics: Chromatography, High Pressure Liquid; Creatinine; Glucose; Glutamine; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Pancreatic Neoplasms; Pancreatitis; Saliva; Silicates; Urine

2009
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
    Human pathology, 2010, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Chi-Square Distribution; Cholangiocarcinoma; DNA-Binding Proteins; Female; Gastrointestinal Neoplasms; Histone Demethylases; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Nuclear Proteins; Pancreatic Neoplasms; Transcription Factors

2010
Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Apr-02, Volume: 143, Issue:1

    Topics: Adenocarcinoma; Animals; DNA; Feasibility Studies; Genetic Therapy; Humans; Injections, Intravenous; Luciferases; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Microscopy, Confocal; Microscopy, Video; Muscle, Skeletal; Nanoparticles; Nanotechnology; Neovascularization, Pathologic; Pancreatic Neoplasms; Polyethylene Glycols; Time Factors; Transfection; Tumor Burden; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor Receptor-1

2010
Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Jan-05, Volume: 149, Issue:1

    Topics: Animals; Cell Line, Tumor; Cross-Linking Reagents; DNA; Female; Gene Transfer Techniques; Genetic Therapy; Injections, Intravenous; Lysine; Mice; Mice, Inbred BALB C; Micelles; Microvessels; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Peptides, Cyclic; Plasmids; Polyethylene Glycols; Polylysine; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Transfection; Vascular Endothelial Growth Factor Receptor-1

2011
Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradation.
    The Journal of biological chemistry, 2011, Jan-14, Volume: 286, Issue:2

    Topics: Amino Acid Sequence; Animals; Calcium Channels; Cell Line, Tumor; Fibroblasts; Humans; Inositol 1,4,5-Trisphosphate Receptors; Lysine; Mice; Molecular Sequence Data; Neuroblastoma; Pancreatic Neoplasms; Pituitary Gland; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Rats; Receptors, Cytoplasmic and Nuclear; Ubiquitin; Ubiquitination

2011
Bioconjugation of luminescent silicon quantum dots for selective uptake by cancer cells.
    Bioconjugate chemistry, 2011, Jun-15, Volume: 22, Issue:6

    Topics: Cell Line, Tumor; Coated Materials, Biocompatible; Folic Acid; Humans; Luminescence; Lysine; Materials Testing; Molecular Imaging; Molecular Structure; Pancreatic Neoplasms; Particle Size; Quantum Dots; Silicon; Stereoisomerism; Surface Properties; Transferrin

2011
The associations of advanced glycation end products and its soluble receptor with pancreatic cancer risk: a case-control study within the prospective EPIC Cohort.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012, Volume: 21, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2012
The cellular level of histone H3 lysine 4 dimethylation correlates with response to adjuvant gemcitabine in Japanese pancreatic cancer patients treated with surgery.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2012, Volume: 38, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Histones; Humans; Immunohistochemistry; Lysine; Male; Methylation; Middle Aged; Pancreatic Neoplasms

2012
Prognostic factors in gemcitabine-cisplatin polychemotherapy regimens in pancreatic cancer: XPD-Lys751Gln polymorphism strikes back.
    International journal of cancer, 2013, Aug-15, Volume: 133, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Female; Gemcitabine; Glycine; Humans; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Xeroderma Pigmentosum Group D Protein

2013
[DIAGNOSTIC VALUE OF TOLBUTAMIDE AND 1-LYSINE IN INSULAR ADENOMA OF THE PANCREAS].
    Revista argentina de endocrinologia y metabolismo, 1964, Volume: 10

    Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hypoglycemia; Lysine; Neoplasms; Pancreatic Neoplasms; Pharmacology; Tolbutamide

1964
Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:4

    Topics: Amino Acids; Animals; Antimetabolites, Antineoplastic; Caco-2 Cells; Cell Line; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dogs; Floxuridine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrolysis; Inhibitory Concentration 50; Lysine; Models, Chemical; Neoplasm Metastasis; Nucleosides; Oligopeptides; Pancreatic Neoplasms; Peptide Transporter 1; Prodrugs; Proline; Symporters; Time Factors

2005
Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2.
    International journal of gastrointestinal cancer, 2005, Volume: 35, Issue:2

    Topics: Antioxidants; Arginine; Ascorbic Acid; Cell Proliferation; Cell Survival; Humans; Lysine; Matrix Metalloproteinases; Neoplasm Invasiveness; Pancreatic Neoplasms; Proline; Tea; Tumor Cells, Cultured

2005
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
    Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2

    Topics: Adenocarcinoma; Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Xeroderma Pigmentosum Group D Protein

2007
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers.
    Molecular carcinogenesis, 2008, Volume: 47, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Histones; Humans; Lysine; Middle Aged; Ovarian Neoplasms; Pancreatic Neoplasms; Predictive Value of Tests; Prognosis; Treatment Failure; Treatment Outcome

2008
MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells.
    Cancer research, 2008, Apr-15, Volume: 68, Issue:8

    Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Molecular Sequence Data; Mucin-1; Pancreatic Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm

2008
N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells.
    Pancreas, 2008, Volume: 36, Issue:4

    Topics: Acetylcysteine; Adenocarcinoma; CD40 Antigens; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lysine; NF-kappa B; Pancreatic Ducts; Pancreatic Neoplasms; Transcription, Genetic

2008
A novel mutation E179K of the MEN1 gene predisposes for multiple endocrine neoplasia-type 1 (MEN1).
    Human mutation, 2000, Volume: 16, Issue:6

    Topics: Adenoma; Adolescent; Adult; Amino Acid Substitution; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glutamic Acid; Humans; Hyperinsulinism; Hyperparathyroidism; Insulinoma; Lysine; Male; Multiple Endocrine Neoplasia Type 1; Mutation, Missense; Nuclear Family; Pancreatic Neoplasms

2000
Evidence for the presence of tumor peptides with corticotropin-releasing-factor-like activity in the ectopic ACTH syndrome.
    The New England journal of medicine, 1971, Aug-19, Volume: 285, Issue:8

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Amino Acids; Animals; Biological Assay; Carcinoma, Bronchogenic; Corticotropin-Releasing Hormone; Dexamethasone; Electrophoresis; Feedback; Hormones, Ectopic; Humans; Lung Neoplasms; Lysine; Metyrapone; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Peptides; Rats; Vasopressins

1971
[The effect of sarcolysin on nucleic acid synthesis in monolayer cultures of human tumor cells].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:6

    Topics: Adenine; Carbon Isotopes; Culture Techniques; Female; Hemangiosarcoma; Humans; Lysine; Melphalan; Mesenchymoma; Neoplasm Proteins; Ovarian Neoplasms; Pancreatic Neoplasms; RNA, Neoplasm; Stomach Neoplasms; Uridine

1970