lysine has been researched along with Cancer of Ovary in 32 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (3.13) | 18.7374 |
1990's | 1 (3.13) | 18.2507 |
2000's | 6 (18.75) | 29.6817 |
2010's | 17 (53.13) | 24.3611 |
2020's | 7 (21.88) | 2.80 |
Authors | Studies |
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Bitler, BG; Dai, Z; Drapkin, R; Karakashev, S; Kossenkov, AV; Lin, J; Liu, H; Moses, R; Zhang, R; Zhou, W | 1 |
Cheng, H; Li, H; Song, W; Wang, J; Wu, F; Zeng, Z; Zhang, Y | 1 |
Li, L; Song, Y; Xi, Y | 1 |
Burke, TR; Hwang, D; Park, H; Rader, C; Tsuji, K | 1 |
Czogalla, B; Han, N; Hester, A; Jeschke, U; Kuhn, C; Mahner, S; Mayr, D; Rottmann, M; Schmoeckel, E; Trillsch, F | 1 |
An, N; Chen, XJ | 1 |
Fujii, T; Hamamoto, R; Honjoh, H; Inoue, F; Kaneko, S; Kashiyama, T; Kojima, M; Komatsu, M; Kukita, A; Miyamoto, Y; Mori-Uchino, M; Osuga, Y; Sone, K; Taguchi, A; Takahashi, Y; Tanikawa, M; Tsuruga, T; Wada, M; Wada-Hiraike, O | 1 |
Czogalla, B; Han, N; Hester, A; Heublein, S; Jeschke, U; Kuhn, C; Mahner, S; Mayr, D; Rottmann, M; Schmoeckel, E; Trillsch, F | 1 |
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW | 1 |
Chen, L; Höti, N; Liu, Y; Thomas, SN; Zhang, H | 1 |
Arend, RC; Jones, BA; Varambally, S | 1 |
Chan, DW; Chen, L; Moore, C; Shih, IM; Song, G; Song, Q; Wang, TL; Yu, Y; Zhang, B; Zhang, H; Zhang, Z; Zhu, H | 1 |
Dai, MS; David, LL; Elferich, J; Li, Y; Shinde, U; Sun, XX | 1 |
Dorn, J; Ferrari, E; Hübscher, U; Imhof, R; Ziegler, N | 1 |
Chen, J; Fu, Y; Li, C; Pang, B; Shen, K; Zhao, J | 1 |
Chen, CK; Chen, MW; Hsiao, M; Hua, KT; Jan, YH; Jeng, YM; Ko, CH; Kuo, ML; Sung, PL; Wang, MY; Wei, LH; Yen, ML | 1 |
Davidson, B; Falnes, PØ; Jakobsson, ME; Moen, A | 1 |
Cho, K; Dou, Y; Hensley-Alford, S; Kotarski, J; Kryczek, I; Liu, R; Munkarah, A; Nagarsheth, N; Peng, D; Sun, Y; Szeliga, W; Tarkowski, R; Vatan, L; Wang, W; Wei, S; Zhao, E; Zhao, L; Zou, W | 1 |
Agnarsson, BA; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Antoniou, AC; Bandera, EV; Banerjee, S; Barile, M; Barrowdale, D; Beckman, MW; Beeghly-Fadiel, A; Benitez, J; Berchuck, A; Bjorge, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Borg, A; Borresen-Dale, AL; Brauch, H; Brenner, H; Broeks, A; Bruinsma, F; Brunet, J; Brüning, T; Burwinkel, B; Butterbach, K; Butzow, R; Buys, SS; Cai, H; Campbell, IG; Cannioto, R; Castillo, D; Chan, SB; Chang-Claude, J; Chenevix-Trench, G; Claes, KB; Collavoli, A; Cook, LS; Couch, FJ; Cox, A; Cramer, D; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Damiola, F; Darabi, H; Dennis, J; Devilee, P; Diez, O; Ding, YC; Doherty, JA; Domchek, SM; Dorfling, CM; Dörk, T; Dunning, AM; Easton, DF; Eccles, DM; Ellis, S; Eunjung, L; Fasching, PA; Feng, B; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Foretova, L; Fostira, F; Friedman, E; Frost, D; Ganz, PA; Gao, YT; Garber, J; García-Closas, M; Gayther, S; Gerdes, AM; Giles, GG; Glasspool, R; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Goode, EL; Goodman, MT; Greene, MH; Gronwald, J; Guénel, P; Hahnen, E; Haiman, CA; Hall, P; Hallberg, E; Hamann, U; Hansen, TV; Hart, SN; Healey, S; Heitz, F; Henderson, BE; Henriksson, K; Hildebrant, MA; Hogdall, C; Hogdall, E; Hogervorst, FB; Hopper, JL; Hosono, S; Hoya, Mde L; Hulick, PJ; Imyanitov, EN; Isaacs, C; Jakubowska, A; James, PA; Janavicius, R; Jensen, A; John, EM; Johnson, N; Jones, M; Kabisch, M; Karlan, BY; Khan, S; Kiemeney, LA; Kjaer, SK; Knight, JA; Konstantopoulou, I; Koppert, LB; Kosma, VM; Kristensen, V; Kupryjanczyk, J; Kwong, A; Laitman, Y; Lambrechts, D; Lazaro, C; Le, N; Lester, J; Levine, D; Li, J; Liang, D; Lindblom, A; Loud, JT; Lu, KH; Lubinski, J; Maerken, TV; Mai, PL; Mannermaa, A; Manoukian, S; Margolin, S; Marme, F; Massuger, LF; Matsuo, K; Maugard, C; Mazoyer, S; McGuffog, L; McNeish, I; Meeks, HD; Meindl, A; Menon, U; Michailidou, K; Milne, RL; Modugno, F; Moes-Sosnowska, J; Montagna, M; Monteiro, AN; Moysich, KB; Narod, S; Nathanson, KL; Ness, R; Neuhausen, SL; Nevanlinna, H; Neven, P; Nussbaum, RL; Offit, K; Öfverholm, A; Olah, E; Oliani, C; Olopade, OI; Olson, JE; Olson, SH; Osorio, A; Ouweland, AM; Park, SK; Pasini, BJ; Pearce, L; Pedersen, IS; Peissel, B; Peixoto, A; Pejovic, T; Pelttari, LM; Peterlongo, P; Pharoah, PD; Phelan, CM; Piedmonte, M; Poole, EM; Pylkäs, K; Radice, P; Ramus, SJ; Rantala, J; Rappaport-Feurhauser, C; Rennert, G; Riboli, E; Risch, H; Robson, M; Rossing, MA; Rudolph, A; Salvesen, HB; Sawyer, EJ; Schildkraut, J; Schmidt, MK; Schoemaker, MJ; Segura, PP; Senter, L; Shah, M; Shimelis, H; Siddiquil, N; Sieh, W; Simard, J; Singer, CF; Sinilnikova, OM; Slager, S; Song, H; Soucy, P; Southey, MC; Spurdle, AB; Stoppa-Lyonnet, D; Swerdlow, A; Teixeira, MR; Teo, SH; Terry, KL; Terry, MB; Tesoriero, A; Thomassen, M; Thompson, PJ; Tihomirova, L; Tischkowitz, M; Tollenaar, RA; Tomlinson, I; Torres, D; Truong, T; Tucker, K; Tung, N; Tworoger, SS; van Rensburg, EJ; Varon-Mateeva, R; Viel, A; Wang, Q; Wappenschmidt, B; Weitzel, JN; Wentzensen, N; Whittermore, AS; Winqvist, R; Woo, YL; Wu, A; Yoon, SY; Zheng, W | 1 |
Chaudhuri, G; Farias-Eisner, R; Ramachandran, I; Ramadoss, S; Roy, S; Sen, S | 1 |
Allis, CD; Cook, RG; Frierson, HF; Fujita, M; Fukusato, T; Iizuka, M; Mizzen, CA; Smith, MM; Takahashi, Y | 1 |
Gui-lan, L; Jin, H; Ping, Y; Ya-li, W; Zhen, L | 1 |
Cai, J; Hu, S; Li, Z; Shen, Y; Wang, J; Wang, Z; Xiao, L; Yu, L | 1 |
Chin, JW; Komander, D; Nguyen, DP; Virdee, S; Ye, Y | 1 |
Bäck, T; Chouin, N; Frost, SH; Hultborn, R; Jacobsson, L; Jensen, H; Lindegren, S | 1 |
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW | 1 |
Capo-chichi, CD; Caslini, C; Nicolas, E; Roland, IH; Xu, XX; Yeung, AT | 1 |
Abbosh, PH; Balch, C; Brannon, KM; Egorin, MJ; Golas, A; Huang, TH; Montgomery, JS; Moseman, AP; Nephew, KP; Novotny, M; Starkey, JA; Zuhowski, EG | 1 |
Abbruzzese, JL; Adsay, NV; Albarracin, C; Bast, RC; Hortobagyi, GN; Hung, MC; Liu, J; Mills, GB; Wang, H; Wei, Y; Xia, W; Yu, D; Zhang, Z | 1 |
Nagy, B; Papp, Z; Páy, A; Rigó, J; Tanyi, J | 1 |
Baumal, R; Marks, A; Sheldon, K | 1 |
Karuzina, NP; Timofeevskaia, EA | 1 |
1 review(s) available for lysine and Cancer of Ovary
Article | Year |
---|---|
Histone Methyltransferase EZH2: A Therapeutic Target for Ovarian Cancer.
Topics: Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Molecular Targeted Therapy; Ovarian Neoplasms; Small Molecule Libraries | 2018 |
31 other study(ies) available for lysine and Cancer of Ovary
Article | Year |
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KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer.
Topics: Animals; Antigen Presentation; Down-Regulation; Female; Humans; Immunity; Lysine; Mice; Ovarian Neoplasms; Retinoblastoma-Binding Protein 2 | 2022 |
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Topics: Autophagy; Beclin-1; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; F-Box Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; MicroRNAs; Ovarian Neoplasms; RNA, Circular; RNA, Messenger; Ubiquitination | 2022 |
Lysine demethylase 3A in hypoxic macrophages promotes ovarian cancer development through regulation of the vascular endothelial growth factor A/Akt signaling.
Topics: Cell Adhesion Molecules; Cell Line, Tumor; Female; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Macrophages; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2023 |
Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Topics: Antibodies, Monoclonal; beta-Lactams; Breast Neoplasms; Cell Proliferation; Female; Humans; Hydrocarbons, Aromatic; Immunoconjugates; Ketones; Lysine; Ovarian Neoplasms; Protein Engineering; Receptor, ErbB-2; Tumor Cells, Cultured | 2019 |
H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology.
Topics: Adult; Aged; Aged, 80 and over; Calcitriol; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Female; Histones; Humans; Kaplan-Meier Estimate; Lysine; Methylation; Middle Aged; Multivariate Analysis; Ovarian Neoplasms; Proportional Hazards Models; Receptors, Calcitriol; Survival Analysis | 2020 |
Long noncoding RNA ATB promotes ovarian cancer tumorigenesis by mediating histone H3 lysine 27 trimethylation through binding to EZH2.
Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Protein Binding; RNA, Long Noncoding; Treatment Outcome | 2021 |
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Ovarian Neoplasms; Prognosis; Quinazolines; RNA, Small Interfering; Transfection; Up-Regulation | 2020 |
The G-Protein-Coupled Estrogen Receptor (GPER) Regulates Trimethylation of Histone H3 at Lysine 4 and Represses Migration and Proliferation of Ovarian Cancer Cells In Vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphorylation; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction | 2021 |
A Specific Mixture of Nutrients Suppresses Ovarian Cancer A-2780 Tumor Incidence, Growth, and Metastasis to Lungs.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Lysine; Matrix Metalloproteinase 9; Mice; Mice, Nude; Micronutrients; Neoplasm Metastasis; Ovarian Neoplasms; Plant Extracts; Proline; Quercetin; Tea; Xenograft Model Antitumor Assays | 2017 |
Targeted Proteomic Analyses of Histone H4 Acetylation Changes Associated with Homologous-Recombination-Deficient High-Grade Serous Ovarian Carcinomas.
Topics: Acetylation; BRCA1 Protein; Carcinoma; DNA Damage; DNA Repair; Female; Histone Deacetylase 6; Histones; Homologous Recombination; Humans; Lysine; Mutation; Ovarian Neoplasms; Protein Processing, Post-Translational; Proteomics | 2017 |
Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors.
Topics: Acetylation; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Humans; Lysine; Ovarian Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proteomics; Sumoylation; Tyrosine; Ubiquitination | 2019 |
Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.
Topics: Amino Acid Sequence; Cell Line, Tumor; Cysteine Endopeptidases; Deubiquitinating Enzymes; DNA Damage; Female; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Ovarian Neoplasms; Protein Binding; Protein Stability; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2014 |
Regulation of human MutYH DNA glycosylase by the E3 ubiquitin ligase mule.
Topics: Amino Acid Substitution; Cell Line, Tumor; Chromatin; DNA Glycosylases; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Lysine; Mutation; Ovarian Neoplasms; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2014 |
EZH2-induced H3K27me3 is associated with epigenetic repression of the ARHI tumor-suppressor gene in ovarian cancer.
Topics: Adenosine; Carcinogenesis; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Female; Gene Knockdown Techniques; Histones; Humans; Lysine; Methylation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polycomb Repressive Complex 2; rho GTP-Binding Proteins; RNA, Small Interfering; Survival Analysis; Tumor Suppressor Proteins | 2015 |
The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.
Topics: Animals; Anoikis; Biomarkers, Tumor; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mice, Inbred NOD; Mice, SCID; Multivariate Analysis; Neoplasm Invasiveness; Ovarian Neoplasms; Peritoneal Neoplasms; Prognosis; Signal Transduction | 2014 |
Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Female; HSP70 Heat-Shock Proteins; Humans; Kaplan-Meier Estimate; Lysine; Methylation; Middle Aged; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Prognosis; Proportional Hazards Models; Protein Processing, Post-Translational | 2015 |
Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy.
Topics: Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Chemokine CXCL10; Chemokine CXCL9; Chemokines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Silencing; Histones; Humans; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Lysine; Mice; Ovarian Neoplasms; Polycomb Repressive Complex 2; Prognosis; Th1 Cells; Tumor Cells, Cultured; Tumor Escape; Xenograft Model Antitumor Assays | 2015 |
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
Topics: Adult; Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Heterozygote; Humans; Logistic Models; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Ovarian Neoplasms; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Assessment; Risk Factors | 2016 |
Lysine-specific demethylase KDM3A regulates ovarian cancer stemness and chemoresistance.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cellular Senescence; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Heterografts; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Mice; Neoplastic Stem Cells; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; SOXB1 Transcription Factors; Tumor Suppressor Protein p53 | 2017 |
Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers.
Topics: Acetylation; Binding Sites; Blotting, Western; Breast Neoplasms; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histones; Humans; Immunohistochemistry; Kidney Neoplasms; Lysine; Male; Neoplasms; Nucleosomes; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Recombinant Proteins; Tissue Array Analysis; Urinary Bladder Neoplasms | 2009 |
The expression of H3K9Ac, H3K14Ac, and H4K20TriMe in epithelial ovarian tumors and the clinical significance.
Topics: Cystadenocarcinoma, Serous; Cystadenoma, Mucinous; Female; Histone Acetyltransferases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms | 2010 |
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase.
Topics: Endopeptidases; Female; Humans; Lysine; Ovarian Neoplasms; Peptides; Protein Engineering; Substrate Specificity; Ubiquitins | 2010 |
In vivo distribution of avidin-conjugated MX35 and (211)At-labeled, biotinylated poly-L-lysine for pretargeted intraperitoneal α-radioimmunotherapy.
Topics: Animals; Antibodies, Monoclonal; Astatine; Avidin; Biotinylation; Bone Marrow; Female; Iodine Isotopes; Isotope Labeling; Kidney; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Polymers; Radioimmunotherapy; Tissue Distribution | 2011 |
Inhibition of matrix metalloproteinase-2 secretion and invasion by human ovarian cancer cell line SK-OV-3 with lysine, proline, arginine, ascorbic acid and green tea extract.
Topics: Amino Acids; Arginine; Ascorbic Acid; Cell Division; Cell Line, Tumor; Enzyme Inhibitors; Female; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Ovarian Neoplasms; Proline; Tea | 2006 |
Histone modifications silence the GATA transcription factor genes in ovarian cancer.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Carcinoma; Cell Line, Tumor; Female; GATA Transcription Factors; GATA4 Transcription Factor; GATA6 Transcription Factor; Gene Silencing; Genes, Tumor Suppressor; Heterochromatin; Histones; Humans; Lysine; Methylation; Ovarian Neoplasms; Tumor Suppressor Proteins | 2006 |
Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatin; Cisplatin; CpG Islands; DNA Methylation; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Lysine; Ovarian Neoplasms; Point Mutation; Tumor Suppressor Proteins | 2006 |
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Histones; Humans; Lysine; Middle Aged; Ovarian Neoplasms; Pancreatic Neoplasms; Predictive Value of Tests; Prognosis; Treatment Failure; Treatment Outcome | 2008 |
[Mutation analysis of the beta-catenin gene in epithelial carcinomas of the ovaries].
Topics: Adult; Age Factors; Aged; beta Catenin; Cadherins; Carcinoma; Cytoskeletal Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Isoleucine; Lysine; Middle Aged; Mutation; Neoplasm Staging; Ovarian Neoplasms; Polymerase Chain Reaction; Serine; Trans-Activators | 2000 |
Targeting of [111In]biocytin to cultured ovarian adenocarcinoma cells using covalent monoclonal antibody-streptavidin conjugates.
Topics: Adenocarcinoma; Female; Humans; In Vitro Techniques; Indium Radioisotopes; Isotope Labeling; Lysine; Ovarian Neoplasms; Radioimmunodetection | 1992 |
[The effect of sarcolysin on nucleic acid synthesis in monolayer cultures of human tumor cells].
Topics: Adenine; Carbon Isotopes; Culture Techniques; Female; Hemangiosarcoma; Humans; Lysine; Melphalan; Mesenchymoma; Neoplasm Proteins; Ovarian Neoplasms; Pancreatic Neoplasms; RNA, Neoplasm; Stomach Neoplasms; Uridine | 1970 |