lysine has been researched along with Breast Cancer in 157 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (5.10) | 18.7374 |
| 1990's | 2 (1.27) | 18.2507 |
| 2000's | 36 (22.93) | 29.6817 |
| 2010's | 78 (49.68) | 24.3611 |
| 2020's | 33 (21.02) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, W; Yao, J; Zhang, T | 1 |
| Feng, T; Gu, R; Guo, Y; Li, K; Li, Q; Li, S; Lin, P; Ou, D; Yuan, H; Zhang, J; Zhao, G | 1 |
| Borkiewicz, L | 1 |
| Enkhbat, G; Miki, Y; Nakanishi, A | 1 |
| Barnon, MT; Beacon, TH; Davie, JR; López, C; Nardocci, G | 1 |
| Sharma, M; Tollefsbol, TO | 1 |
| Bernstein, KA; Böhm, S; Lee, AV; Li, Z; Luong, TT; Parker, PS; Priedigkeit, N; Rapchak, K | 1 |
| Aruga, T; Iwasa, T; Iwata, H; Kaneda, A; Kaneko, K; Kawabata, A; Kobayashi, K; Lee, MJ; Masuda, N; Nakamura, R; Nishimura, Y; Saji, S; Seike, T; Tamura, K; Tokunaga, E; Trepel, JB; Tsurutani, J; Yamamoto, Y; Yamashita, T; Yonemori, K; Yuno, A | 1 |
| Iqbal, J; Lee, DY; Salahuddin, T | 1 |
| Chen, XL; Ren, YX; Ren, ZF; Shi, YY; Tang, LY; Wang, B; Yang, YZ; Zhou, M | 1 |
| Archer, KJ; Cousin, L; Garrett, T; Kelly, DL; Lyon, DE; Yao, Y | 1 |
| Crowe, DL; Kramer, K; Wu, J | 1 |
| Gan, XL; Guan, JX; Ren, YX; Ren, ZF; Tang, LY; Wang, B; Weng, ZJ; Yang, YZ; Zhang, XF; Zhou, M | 1 |
| Deng, J; Liao, X | 1 |
| Ge, L; Huang, X; Sang, K; Yi, T; Zhou, J; Zhou, X | 1 |
| Andrechek, ER; Daldoul, K; Harris, LN; Hirukawa, A; Lavoie, C; Muller, WJ; Park, M; Rennhack, JP; Sanguin-Gendreau, V; Singh, S; Smith, HW; Swiatnicki, M; Varadan, V; Wang, J; Westbrook, TF; Zuo, D | 1 |
| Burke, TR; Hwang, D; Park, H; Rader, C; Tsuji, K | 1 |
| Feng, D; Gao, J; Gao, T; Hou, Y; Huang, W; Leng, S; Liu, R; Liu, W; Qiu, R; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zhang, K; Zhang, X; Zheng, Y | 1 |
| Hjelmeland, AB; Patel, RP | 1 |
| Hu, X; Li, DQ; Liu, HY; Liu, YY; Shao, ZM; Yang, F; Zhang, FL; Zhang, L | 1 |
| Bao, H; Gao, X; Liu, L; Yue, L; Zhang, L; Zhu, W | 1 |
| Bomhard, A; Brückner, F; Lisowska, H; Lundholm, L; Płódowska, M; Sterr, C; Svetličič, M | 1 |
| Crocamo, S; Delbue, D; Lemos, LGT; Lucena, PI; Magalhães, LM; Maia, RC; Mendonça, BS; Nestal de Moraes, G; Oliveira, CAB; Robaina, MC; Teixeira, FR; Viola, JPB | 1 |
| Chen, Y; Ding, L; Hao, Y; He, C; Yao, H; Yu, L | 1 |
| Caggiano, R; Di Bonito, M; Di Mauro, A; Faraonio, R; Feola, A; Gigantino, V; Porcellini, A; Romano, A; Zuchegna, C | 1 |
| Choi, JH; Kim, JJ; Lee, SY; Miller, KM; Woo, HG; Xhemalce, B | 1 |
| Campbell, PA; Crawley, CD; Garofalo, A; Khramtsova, GF; Nichols, JW; Olopade, OI; Weichselbaum, RR; Wu, L; Yamini, B | 1 |
| Abedi, F; Akbarzadeh, A; Alizadeh, E; Annabi, N; Baradaran, B; Davaran, S; Moghaddam, SV | 1 |
| Ignatov, A; Kalinski, T; Nass, N; Scheifele, C; Zhu, Q | 1 |
| Cao, Q; Chen, K; Cooke, JP; Gao, X; Lee, MG; Lv, J; Meng, Q; Tomoiaga, AS; Wang, G; Xia, B; Yi, Y; Zhang, L; Zhang, M; Zhao, D; Zhu, S | 1 |
| Boeer, B; Brucker, SY; Hahn, M; Hartkopf, A; Marx, M; Oberlechner, E; Ohlinger, R; Paepke, S; Röhm, C; Schneider, J; Schoenfisch, B | 1 |
| Dashtestani, F; Ganji, M; Haghiralsadat, F; Hakimian, F; Neghab, HK; Soheilifar, MH | 1 |
| Anwar, T; Gonzalez, ME; Kleer, CG | 1 |
| Chen, L; da Silva, SR; Gao, SJ; Ju, E; Li, T; Wang, X; Wei, S; Zhang, X | 1 |
| Abedin, MR; Aiardo, R; Barua, D; Barua, S; Powers, K | 1 |
| Cao, D; Ding, H; Hou, J; Huang, B; Lin, C; Liu, J; Liu, L; Liu, X; Liu, Y; Lu, J; Wang, G; Zhang, N; Zhang, X; Zhang, Y | 1 |
| Cardoso, ME; Rey Ríos, AM; Savio, E; Tejería, E; Terán, M; Zirbesegger, K | 1 |
| Gu, Y; Guo, G; Li, L; Wang, F; Wang, N; Wang, X; Xiong, Y; Zhu, M | 1 |
| Armstrong, SA; Baselga, J; Castel, P; Chan, C; Dickler, MN; Elkabets, M; Hendrickson, RC; Leslie, CS; Osmanbeyoglu, HU; Scaltriti, M; Toska, E | 1 |
| Ahn, SG; Bae, E; Ha, J; Jeong, J; Jung, SM; Kim, JH; Kim, M; Kim, SJ; Lee, J; Lee, JH; Lee, S; Lee, YS; Ooshima, A; Park, J; Park, JS; Park, SH; Seo, D; Shin, D; van Loo, G; Yang, KM | 1 |
| Chen, H; Liu, YB; Ngernyuang, N; Oh, D; Schwartz, LM; Shao, R; Yan, W | 1 |
| Azevedo, FVPV; Barbosa, MJ; Borges, BC; da Silva, CV; da Silva, MS; Elias, MC; Gimenes, SNC; Lopes, DS; Oliveira Júnior, RJ; Polloni, L; Rodrigues, RS; Rodrigues, VM; Silva, MA; Teixeira, SC; Yoneyama, KAG | 1 |
| An, W; Jeong, D; Kim, J; Kim, K; Kim, M; Koh, J; Lee, S; Lu, JF; Punj, V; Shin, H; Shin, Y; Ulmer, TS | 1 |
| Chen, L; Cheng, H; Li, W; Liu, C; Liu, Y; Zhang, B; Zhang, M | 1 |
| Han, D; Li, X; Lu, J; Ma, M; Ma, Y; Tan, J; Wang, Y; Xu, G; Yao, R; Zhao, Y | 1 |
| Baeumner, AJ; Buchner, M; García Calavia, P; Hirsch, T; Kröninger, A; Marín, MJ; Muhr, V; Russell, DA | 1 |
| Ding, C; Ding, W; Du, J; Feng, XH; Fu, P; Guan, KL; Jin, J; Jin, K; Li, F; Shao, L; van Dam, H; Wang, A; Wang, S; Wei, B; Yang, B; Zhang, L; Zhang, Z; Zheng, M | 1 |
| Bonini, M; Brien, JO; Dean, AE; Gao, Y; Gius, D; Hart, R; Horikoshi, N; Jiang, H; Kieffer, MB; Liu, G; Park, SH; Quan, S; Satchell, KJF; Stauffer, ME; Tran, EL; Zhu, Y; Zou, X | 1 |
| Andrade, N; Correia-Branco, A; Ferreira, AC; Martel, F; Silva, C; Soares, ML; Sonveaux, P; Stephenne, J | 1 |
| Ban, YJ; Caslini, C; Chen, XS; Hong, S; Ince, TA | 1 |
| Bernard-Gallon, D; Bignon, YJ; Dagdemir, A; Durif, J; Ngollo, M | 1 |
| Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y | 1 |
| Bourdon, V; Dreyfus, H; Eisinger, F; Extra, JM; Geneix, J; Gesta, P; Hassanein, M; Huiart, L; Jacquemier, J; Lidereau, R; Meynard, P; Noguchi, T; Nogues, C; Petrot, D; Peyrat, JP; Rabayrol, L; Sobol, H; Viens, P | 1 |
| Jin, C; Tang, LY; Tang, Y; Wang, X; Zhang, YE | 1 |
| Chang, CK; Chen, CL; Chen, SH; Chou, YA; Dong, JJ; Hsiao, M; Huang, MS; Jan, YH; Lai, TC; Liang, PH; Lin, YF; Liu, HG; Teng, KH; Tian, WT; Yang, CJ | 1 |
| Debald, M; Hartmann, G; Kuhn, W; Linke, A; Schildberg, FA; Walgenbach, K; Walgenbach-Brünagel, G | 1 |
| D'Argenio, V; Esposito, MV; Frisso, G; Gilder, JA; Salvatore, F | 1 |
| Bi, FF; Cao, C; Cao, JM; Li, D; Liu, B; Yang, Q | 1 |
| Barton, MC; Jiang, S; Li, B; Li, H; Li, W; Li, Y; Peng, D; Ren, Y; Shi, X; Stratton, S; Tanaka, K; Wen, H; Wu, J; Xi, Y; Xia, Z | 1 |
| Venkatesh, S; Workman, JL | 1 |
| Chen, Y; Jacobson, F; Kim, MT; Marhoul, J | 1 |
| Li, H; Li, Y; Shi, X; Wen, H | 1 |
| Benz, CC; Gabriel, BS; Gibson, BW; Hanson, IM; Held, JM; Kehasse, A; Rothschild, DE; Schilling, B; Scott, GK; Wilson-Edell, KA; Yau, C; Yevtushenko, MA | 1 |
| Chen, YX; Du, YJ; Gao, CJ; Gu, LC; Li, Y; Liang, N; Ma, R; Ning, SL; Pang, Q; Sun, JP; Wang, HM; Xiao, KH; Xu, YF; Yang, DX; Yang, F; Yao, W; Yu, X; Zhang, LL; Zhang, Y | 1 |
| Beck, AH; Collins, LC; Hazra, A; Healey, MA; Hu, R; Schnitt, SJ; Tamimi, RM | 1 |
| Khattar, V; Thottassery, JV | 1 |
| Chen, F; Deng, L; Mo, Q; Song, Y; Wei, L; Wu, B; Yao, Y; Zhang, L | 1 |
| Cheng, R; Deng, C; Meng, F; Xie, F; Zhang, J; Zhong, Y; Zhong, Z | 1 |
| Anjanappa, M; Appaiah, HN; Badve, S; Bhat-Nakshatri, P; Crooks, PA; Gilley, D; Mathews, W; Nakshatri, H; Sweeney, C; Tanaka, H | 1 |
| Chattopadhyay, A; Das, D; Ghosh, A; Sengupta, A | 1 |
| Davidson, B; Falnes, PØ; Jakobsson, ME; Moen, A | 1 |
| Agnarsson, BA; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Antoniou, AC; Bandera, EV; Banerjee, S; Barile, M; Barrowdale, D; Beckman, MW; Beeghly-Fadiel, A; Benitez, J; Berchuck, A; Bjorge, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Borg, A; Borresen-Dale, AL; Brauch, H; Brenner, H; Broeks, A; Bruinsma, F; Brunet, J; Brüning, T; Burwinkel, B; Butterbach, K; Butzow, R; Buys, SS; Cai, H; Campbell, IG; Cannioto, R; Castillo, D; Chan, SB; Chang-Claude, J; Chenevix-Trench, G; Claes, KB; Collavoli, A; Cook, LS; Couch, FJ; Cox, A; Cramer, D; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Damiola, F; Darabi, H; Dennis, J; Devilee, P; Diez, O; Ding, YC; Doherty, JA; Domchek, SM; Dorfling, CM; Dörk, T; Dunning, AM; Easton, DF; Eccles, DM; Ellis, S; Eunjung, L; Fasching, PA; Feng, B; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Foretova, L; Fostira, F; Friedman, E; Frost, D; Ganz, PA; Gao, YT; Garber, J; García-Closas, M; Gayther, S; Gerdes, AM; Giles, GG; Glasspool, R; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Goode, EL; Goodman, MT; Greene, MH; Gronwald, J; Guénel, P; Hahnen, E; Haiman, CA; Hall, P; Hallberg, E; Hamann, U; Hansen, TV; Hart, SN; Healey, S; Heitz, F; Henderson, BE; Henriksson, K; Hildebrant, MA; Hogdall, C; Hogdall, E; Hogervorst, FB; Hopper, JL; Hosono, S; Hoya, Mde L; Hulick, PJ; Imyanitov, EN; Isaacs, C; Jakubowska, A; James, PA; Janavicius, R; Jensen, A; John, EM; Johnson, N; Jones, M; Kabisch, M; Karlan, BY; Khan, S; Kiemeney, LA; Kjaer, SK; Knight, JA; Konstantopoulou, I; Koppert, LB; Kosma, VM; Kristensen, V; Kupryjanczyk, J; Kwong, A; Laitman, Y; Lambrechts, D; Lazaro, C; Le, N; Lester, J; Levine, D; Li, J; Liang, D; Lindblom, A; Loud, JT; Lu, KH; Lubinski, J; Maerken, TV; Mai, PL; Mannermaa, A; Manoukian, S; Margolin, S; Marme, F; Massuger, LF; Matsuo, K; Maugard, C; Mazoyer, S; McGuffog, L; McNeish, I; Meeks, HD; Meindl, A; Menon, U; Michailidou, K; Milne, RL; Modugno, F; Moes-Sosnowska, J; Montagna, M; Monteiro, AN; Moysich, KB; Narod, S; Nathanson, KL; Ness, R; Neuhausen, SL; Nevanlinna, H; Neven, P; Nussbaum, RL; Offit, K; Öfverholm, A; Olah, E; Oliani, C; Olopade, OI; Olson, JE; Olson, SH; Osorio, A; Ouweland, AM; Park, SK; Pasini, BJ; Pearce, L; Pedersen, IS; Peissel, B; Peixoto, A; Pejovic, T; Pelttari, LM; Peterlongo, P; Pharoah, PD; Phelan, CM; Piedmonte, M; Poole, EM; Pylkäs, K; Radice, P; Ramus, SJ; Rantala, J; Rappaport-Feurhauser, C; Rennert, G; Riboli, E; Risch, H; Robson, M; Rossing, MA; Rudolph, A; Salvesen, HB; Sawyer, EJ; Schildkraut, J; Schmidt, MK; Schoemaker, MJ; Segura, PP; Senter, L; Shah, M; Shimelis, H; Siddiquil, N; Sieh, W; Simard, J; Singer, CF; Sinilnikova, OM; Slager, S; Song, H; Soucy, P; Southey, MC; Spurdle, AB; Stoppa-Lyonnet, D; Swerdlow, A; Teixeira, MR; Teo, SH; Terry, KL; Terry, MB; Tesoriero, A; Thomassen, M; Thompson, PJ; Tihomirova, L; Tischkowitz, M; Tollenaar, RA; Tomlinson, I; Torres, D; Truong, T; Tucker, K; Tung, N; Tworoger, SS; van Rensburg, EJ; Varon-Mateeva, R; Viel, A; Wang, Q; Wappenschmidt, B; Weitzel, JN; Wentzensen, N; Whittermore, AS; Winqvist, R; Woo, YL; Wu, A; Yoon, SY; Zheng, W | 1 |
| Hur, W; Hwang, JT; Jeong, JC; Kang, MR; Kim, EJ; Kwon, YS; Park, JH; Park, UH; Song, BJ; Um, SJ; Yoon, SK | 1 |
| Boyd, JR; Browne, G; Gordon, JA; Lian, JB; Messier, TL; Stein, GS; Stein, JL; Tye, CE | 1 |
| Boulding, T; Bullman, A; Dahlstrom, JE; Dunn, J; Hardy, K; McCuaig, R; Rao, S; Sutton, CR; Tu, W; Wu, F; Yip, D | 1 |
| Boyd, JR; Gordon, JA; Lian, JB; Messier, TL; Stein, GS; Stein, JL | 1 |
| Gius, D; O'Brien, J; Santa-Maria, CA; Zhu, Y; Zou, X | 1 |
| Carbonaro, M; Chiang, YL; Giannakakou, P; He, B; Hu, J; Jing, H; Lin, H; Negrón Abril, YL; Southard, T; Stupinski, J; Weiser, K; Weiss, RS | 1 |
| Guo, G; Ramadoss, S; Wang, CY | 1 |
| Bradner, J; Brown, M; Cheng, H; Dreijerink, KM; Groner, AC; Lin, CY; Ohlson, CE; Reyes, J; Roberts, TM; Spangle, JM; Zhao, JJ | 1 |
| Clevenger, CV; Craig, JM; Feeney, YB; Fiorillo, AA; Harrell, JC; Medler, TR | 1 |
| Jang, JH; Kim, J; Kim, MS; Kim, YZ; Lee, EH; Lee, SH | 1 |
| Hyun, S; Kim, S; Lee, Y; Yu, J | 1 |
| Deb, M; Kar, S; Parbin, S; Patra, SK; Pradhan, N; Rath, SK; Sengupta, D | 1 |
| Ding, X; Duan, Y; Gao, J; Huo, D; Liu, Z; Shan, L; Shang, Y; Shi, L; Su, D; Wang, Y; Wu, H; Xuan, C; Ye, Z; Zhang, K; Zhou, X | 1 |
| Chan, CH; Frohman, MA; Lee, HJ; Li, CF; Powers, S; Ruan, D; Thompson, PA | 1 |
| Jiao, Y; Lu, M; Wang, Y; Yan, S; You, D; Zhao, H | 1 |
| Asano, S; Barbas, CF; Fuller, RP; Nilchan, N; Patterson, JT; Rader, C; Roush, WR; Wilson, HD | 1 |
| Bhatia, A; Chen, M; Dong, H; Guo, J; Hou, Y; Jayaprakash, P; Li, W; O'Brien, K; Sahu, D; Schmidt, T; Situ, AJ; Tong, C; Tsen, F; Ulmer, TS; Woodley, DT; Ying, Q; Zou, M | 1 |
| Beck, A; Glass, B; Kuperwasser, C; Ni, TK; Skibinski, A; Wronski, A; Zhou, W | 1 |
| Andreas, L; Ignatov, A; Kalinski, T; Nass, N; Sel, S; Weißenborn, C | 1 |
| Chakravarti, D; Chen, JR; Chen, P; Deng, P; DePinho, RA; Dey, P; Lan, Z; Li, J; Liang, X; Liao, W; Lu, X; Navone, NM; Shah, S; Shang, X; Spring, DJ; Tang, M; Troncoso, P; Wang, G; Wang, YA; Zhang, J; Zhao, D | 1 |
| Brown, M; Chi, D; Cook, J; de Laat, W; Dreijerink, KMA; Font-Tello, A; Groner, AC; Gu, L; Lim, E; Lin, CY; Long, HW; Rao, PK; Reyes, J; Vos, ESM | 1 |
| Chen, J; Lei, QY; Li, JT; Xu, YY; Yang, HB; Yao, CB; Yin, M; Zhang, M; Zhang, Y; Zhao, XN | 1 |
| Atadja, P; Bhalla, K; Fiskus, W; Nechtman, J; Rao, R; Shen, J; Tang, Y; Yang, Y | 1 |
| Kagey, JD; Kapoor-Vazirani, P; Powell, DR; Vertino, PM | 1 |
| Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J | 1 |
| Jiang, ZW; Mei, ZR; Tao, L; Wu, HP; Zhu, XG | 1 |
| Huang, YH; Lin, YJ; Liu, XJ; Zhen, YS; Zhen, YZ | 1 |
| Chernov, AV; Remacle, AG; Sounni, NE; Strongin, AY | 1 |
| Lin, YJ; Zhen, YS | 1 |
| Allis, CD; Cook, RG; Frierson, HF; Fujita, M; Fukusato, T; Iizuka, M; Mizzen, CA; Smith, MM; Takahashi, Y | 1 |
| Chen, Y; Domann, FE; Hitchler, MJ; Weigel, RJ; Woodfield, GW | 1 |
| Andò, S; Barone, I; Beyer, A; Corona-Rodriguez, A; Cui, Y; Fuqua, SA; Giordano, C; Herynk, MH; Selever, J | 1 |
| Bebenek, M; Lu, A; Mann, M; Pudełko, M; Wiśniewski, JR; Ziółkowski, P; Zougman, A | 1 |
| Chaerkady, R; Davidson, NE; Kensler, TW; Pandey, A; Shaw, PG; Zhou, Q | 1 |
| Buccheri, S; Caccamo, N; Cicero, G; D'Asaro, M; Dieli, F; Eberl, M; Guggino, G; Hayday, AC; La Mendola, C; Meraviglia, S; Orlando, V; Roberts, A; Scarpa, F; Stassi, G; Todaro, M; Vermijlen, D | 1 |
| Breiling, A; Croce, CM; de Souza Rocha Simonini, P; Diederichs, S; Gupta, N; Hoheisel, JD; Lyko, F; Malekpour, F; Malekpour, M; Mayer, D; Najmabadi, H; Omranipour, R; Riazalhosseini, Y; Sahin, O; Volinia, S; Youns, M | 1 |
| Chen, X; Chen, Y; Hsu, SC; Hung, MC; Huo, LF; Kan, SF; Labaff, AM; Lang, J; Li, CW; Li, LY; Lim, SO; Song, H; Wang, Y; Xie, X; Zhang, K; Zhao, Y | 1 |
| Akiyama, SK; Olden, K; Ray, DM; Roberts, JD; Rogers, BA; Sunman, JA | 1 |
| Flockhart, DA; Huang, TH; Huang, Y; Li, L; Liu, Y; Nephew, KP; Shen, C; Skaar, TC; Teng, M; Wang, G; Wang, Y; Wang, Z; Yan, P; Zhao, Y | 1 |
| de Lumen, BO; Hernández-Ledesma, B; Hsieh, CC | 1 |
| Das, PM; Huynh, FC; Jones, FE; Mitra, D | 1 |
| Cavalli, LR; da Costa Prando, E; Rainho, CA | 1 |
| Balint, E; Boros, IM; Toth, M | 1 |
| Altura, RA; Bianchi, C; Cheng, Y; Chin, YE; Cooper, ZA; Holloway, MP; Ma, L; Riolo, MT; Yakirevich, E | 1 |
| Duan, Y; Li, Y; Liu, P; Qi, X; Sun, Y; Wang, H | 1 |
| Gerard, B; Sanders, MA; Shekhar, MP; Tait, L; Visscher, DW | 1 |
| Damante, G; Di Loreto, C; Marasco, D; Poletto, E; Poletto, M; Puglisi, F; Tell, G | 1 |
| Chin, YR; Finley, LW; Fukushima, H; Gao, D; Gygi, SP; Haigis, MC; Inuzuka, H; Lau, AW; Nakayama, K; Pandolfi, PP; Shaik, S; Teruya-Feldstein, J; Toker, A; Wan, L; Wang, Z; Wei, W; Yang, W; Zhai, B | 1 |
| Barnhart, TE; Cai, W; Chen, X; Hong, H; Nayak, TR; Niu, G; Orbay, H; Valdovinos, HF; Zhang, Y | 1 |
| Desaire, H; Finney, J; Go, EP; Lantz, M; Moon, H; Mure, M; Rebecchi, K; Xu, L | 1 |
| Benghuzzi, H; Brinkley, J; Copeland, L; Streckfus, C; Tucci, M | 1 |
| BABINEAU, LM; BEGIN, N; BERLINGUET, L; DUNNIGAN, J; MARTEL, F | 1 |
| Carlberg, C; Frank, C; Lempiäinen, H; Matilainen, M; Molnár, F | 1 |
| Barbas, CF; Das, S; Lerner, RA; Li, LS; Matsushita, M; Rader, C; Sinha, SC | 1 |
| Cross, JV; Hannink, M; Lo, SC; Templeton, DJ; Zhang, DD | 1 |
| Herédi-Szabó, K; Lovas, S; Lubke, J; Murphy, RF; Toth, G | 1 |
| Dewhirst, MW; Greenberg, CS; Lai, TS; Mazooz, G; Mehlman, T; Neeman, M | 1 |
| Kovalchuk, O; Pogribny, IP; Tryndyak, VP | 1 |
| Cui, Y; Curran, EM; Fuqua, SA; Kumar, R; Liu, Y; Niu, A; Pestell, R | 1 |
| Degani, H; Eshhar, Z; Kalchenko, V; Makovitzki, A; Papo, N; Seger, D; Shai, Y | 1 |
| Azhdarinia, A; Chanda, M; Greenwell, AC; Karacalioglu, AO; Kim, EE; Kohanim, S; Mendez, R; Oh, C; Yang, DJ; Yu, DF | 1 |
| Ranson, M; Saunders, DN; Stillfried, GE | 1 |
| Argalásová, S; Kalousová, M; Mestek, O; Petruzelka, L; Soukupová, J; Tesarová, P; Trnková, B; Zima, T | 1 |
| Wang, Y; Zou, Y | 1 |
| Andrews, LG; Berletch, JB; Katiyar, SK; Liu, C; Love, WK; Tollefsbol, TO | 1 |
| Daniel, AR; Faivre, EJ; Lange, CA | 1 |
| Abbruzzese, JL; Adsay, NV; Albarracin, C; Bast, RC; Hortobagyi, GN; Hung, MC; Liu, J; Mills, GB; Wang, H; Wei, Y; Xia, W; Yu, D; Zhang, Z | 1 |
| Bonanno, E; Calvani, M; Mazzarelli, P; Pucci, S; Sesti, F; Spagnoli, LG | 1 |
| Birrane, G; Carvalho, MA; Foulkes, WD; Goldgar, DE; Grist, SA; Hamel, N; Joosse, SA; Ladias, JA; Monteiro, AN; Nederlof, PM; Novak, D; Quenneville, LA; Soni, A; Tavtigian, SV; Tischkowitz, M; van Beers, EH; Wong, N | 1 |
| Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ | 1 |
| Goto, M; Hamada, T; Higashi, M; Nishida, Y; Nomoto, M; Tsutsumida, H; Yamada, N; Yonezawa, S | 1 |
| Bachmeier, BE; Friess, U; Nerlich, AG; Rohrbach, H; Schleicher, ED | 1 |
| Cheng, X; Collins, RE; Jia, D; Kapoor-Vazirani, P; Peng, J; Powell, DR; Sharma, D; Subramanian, K; Vertino, PM | 1 |
| Ahmed, S; Boumber, Y; Charo, C; Cheng, AS; Furukawa, K; Gold, DL; Huang, TH; Issa, JP; Kondo, Y; Kwabi-Addo, B; Sekido, Y; Shen, L; Urano, T; Yamochi, T | 1 |
| Bebenek, M; Krüger, S; Mann, M; Pudełko, M; Wiśniewski, JR; Ziółkowski, P; Zougman, A | 1 |
| Koziol, M; Mikolajski, K; Rozek-Lesiak, K; Scheller, S | 1 |
| Malycha, P; Mountford, C | 1 |
| Burns, MR; Cai, F; Carlson, CL; Devens, BH; O'Day, CL; Vanderwerf, SM; Webb, HK; Weeks, RS | 1 |
| Blomgren, H; Hammarström, S; Petrini, B; Rotstein, S; Wasserman, J | 1 |
| Carlino, JA; Niu, EM; Sherman, MR; Stevens, YW; Tuazon, FB | 1 |
| Bustin, M; Sluyser, M | 1 |
| Hersh, EM; Ohno, R | 1 |
| Bernard-Weil, E; Guillemant, S | 1 |
| Bürgi, W; Schärer, HU | 1 |
| Bojan, O; Mustea, I; Preda, N | 1 |
5 review(s) available for lysine and Breast Cancer
| Article | Year |
|---|---|
Histone 3 Lysine 27 Trimethylation Signature in Breast Cancer.
Topics: Breast Neoplasms; Chromatin; DNA Methylation; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Protein Processing, Post-Translational | 2021 |
Lysine-Specific Demethylase 1 (LSD1)-Mediated Epigenetic Modification of Immunogenicity and Immunomodulatory Effects in Breast Cancers.
Topics: Breast Neoplasms; Epigenesis, Genetic; Female; Histone Demethylases; Humans; Immune Checkpoint Inhibitors; Immunity; Lysine; Tumor Microenvironment | 2023 |
Noncanonical Functions of the Polycomb Group Protein EZH2 in Breast Cancer.
Topics: Breast Neoplasms; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Lysine; Methylation | 2021 |
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.
Topics: Acetylation; Aging; Biomarkers, Tumor; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Incidence; Longevity; Lysine; Molecular Targeted Therapy; Neoplasm Metastasis; Phenotype; Recurrence; Sirtuin 3; Superoxide Dismutase | 2016 |
"Defective" receptors in steroid-resistant conditions may be proteolytic artifacts.
Topics: Animals; Breast; Breast Neoplasms; Centrifugation, Density Gradient; Cytosol; Drug Resistance; Endometrium; Endopeptidases; Female; Humans; Kidney; Leukemia; Leupeptins; Liver; Lysine; Macromolecular Substances; Male; Molybdenum; Osmolar Concentration; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Substrate Specificity; Ultracentrifugation; Uterine Neoplasms | 1986 |
3 trial(s) available for lysine and Breast Cancer
| Article | Year |
|---|---|
Efficacy and exploratory biomarker analysis of entinostat plus exemestane in advanced or recurrent breast cancer: phase II randomized controlled trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; Estrogen Receptor alpha; Female; Humans; Lysine; Neoplasm Recurrence, Local; Receptors, Estrogen | 2023 |
Lysine-urethane-based tissue adhesion for mastectomy-an approach to reducing the seroma rate?
Topics: Adult; Breast Neoplasms; Drainage; Female; Humans; Lysine; Mastectomy; Middle Aged; Plastic Surgery Procedures; Postoperative Complications; Prospective Studies; Quality of Life; Seroma; Surgical Tape; Suture Techniques; Tissue Adhesions; Tissue Adhesives; Treatment Outcome; Urethane | 2021 |
In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients.
Topics: Adjuvants, Immunologic; Aged; Breast Neoplasms; Cell Proliferation; Chemokines; Cytokines; Diphosphonates; Disease Progression; Esterases; Female; Hemiterpenes; Humans; Imidazoles; Immunotherapy; Interferon-gamma; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Count; Lysine; Middle Aged; Mucin-1; Organophosphorus Compounds; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Salvage Therapy; T-Lymphocyte Subsets; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Tumor Necrosis Factor Receptor Superfamily, Member 7; Zoledronic Acid | 2010 |
149 other study(ies) available for lysine and Breast Cancer
| Article | Year |
|---|---|
[Knockdown of lysine-specific demethylase 3A (KDM3A) inhibits the invasion and migration of MDA-MB-231 breast cancer cells and arrests the cell cycle in the G0/G1 phase].
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasm Invasiveness | 2021 |
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Protein Domains; Protein Stability; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Treatment Outcome; Tripartite Motif Proteins; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination | 2021 |
The BRCA2 missense mutation K2497R suppressed self-degradation and increased ATP production and cell proliferation.
Topics: Adenosine Triphosphate; Amino Acid Sequence; BRCA2 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; HEK293 Cells; HSP27 Heat-Shock Proteins; Humans; Lysine; Mutation, Missense; Peptides; Protein Binding; Proteolysis; Ubiquitin; Ubiquitination | 2022 |
The key role of differential broad H3K4me3 and H3K4ac domains in breast cancer.
Topics: Breast Neoplasms; Chromatin; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Transcription Initiation Site | 2022 |
Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Epigenesis, Genetic; Female; Genistein; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Isothiocyanates; Lysine; Sulfoxides | 2022 |
Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer.
Topics: Breast Neoplasms; Cisplatin; DNA; Female; Genomic Instability; Humans; Lysine; Proteasome Endopeptidase Complex; Recombination, Genetic; RecQ Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2022 |
Survival is associated with repressive histone trimethylation markers in both HR-positive HER2-negative and triple-negative breast cancer patients.
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Histones; Humans; Lysine; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Progesterone; Triple Negative Breast Neoplasms | 2023 |
Comparison of serum metabolomics in women with breast Cancer Prior to Chemotherapy and at 1 year: cardiometabolic implications.
Topics: Amines; Amino Acids; Breast Neoplasms; Cardiovascular Diseases; Female; Humans; Lysine; Tandem Mass Spectrometry | 2023 |
Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer.
Topics: Acetoacetates; Animals; Breast Neoplasms; Female; Humans; Lysine; Mice; Obesity; PPAR gamma; Tumor Microenvironment | 2023 |
Combined low levels of H4K16ac and H4K20me3 predicts poor prognosis in breast cancer.
Topics: Breast Neoplasms; Female; Histones; Humans; Lysine; Methylation; Prognosis | 2023 |
Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer.
Topics: Breast Neoplasms; Female; Histones; Humans; Immunotherapy; Lactic Acid; Lysine; Neoplasms; Prognosis; Tumor Microenvironment | 2023 |
Activation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway.
Topics: Acetylation; Adult; Anion Exchange Protein 1, Erythrocyte; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Interleukin-8; Lysine; Middle Aged; Neoplasm Invasiveness; NF-kappa B; RNA, Long Noncoding; Signal Transduction; Transcriptional Activation; Up-Regulation | 2019 |
Reduction of Global H3K27me
Topics: Adult; Animals; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Interferon Type I; Lysine; Methylation; Mice; Models, Biological; Molecular Targeted Therapy; Polycomb Repressive Complex 2; Receptor, ErbB-2; Retroelements; Trastuzumab; Up-Regulation | 2019 |
Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Topics: Antibodies, Monoclonal; beta-Lactams; Breast Neoplasms; Cell Proliferation; Female; Humans; Hydrocarbons, Aromatic; Immunoconjugates; Ketones; Lysine; Ovarian Neoplasms; Protein Engineering; Receptor, ErbB-2; Tumor Cells, Cultured | 2019 |
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Databases, Genetic; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational | 2019 |
SOD2 acetylation and deacetylation: Another tale of Jekyll and Hyde in cancer.
Topics: Acetylation; Breast Neoplasms; Cellular Reprogramming; Humans; Lysine; Sirtuin 3 | 2019 |
Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer.
Topics: Acetylation; Antineoplastic Agents; Breast Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cyclin B1; DNA Damage; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; N-Terminal Acetyltransferases; Radiation, Ionizing; Sirtuin 2; Transcription Factors | 2020 |
Systematic analysis of lysine acetylome and succinylome reveals the correlation between modification of H2A.X complexes and DNA damage response in breast cancer.
Topics: Acetylation; Adult; Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; Cell Line, Tumor; Cell Survival; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; MCF-7 Cells; Middle Aged; Nuclear Proteins; Nucleophosmin; Proteomics; Succinic Acid; Up-Regulation | 2020 |
Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells.
Topics: Acetylation; Alpha Particles; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Clone Cells; Female; Gamma Rays; Heterochromatin; Histones; Humans; Hydroxamic Acids; Lysine; Neoplastic Stem Cells; Radiation Exposure; Spheroids, Cellular | 2020 |
Expression of nuclear XIAP associates with cell growth and drug resistance and confers poor prognosis in breast cancer.
Topics: Apoptosis; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Multivariate Analysis; Mutant Proteins; Mutation; NF-kappa B; Polyubiquitin; Prognosis; Protein Domains; Receptors, Cell Surface; Survival Analysis; Ubiquitination; X-Linked Inhibitor of Apoptosis Protein | 2020 |
Lysine demethylase KDM3A regulates nanophotonic hyperthermia resistance generated by 2D silicene in breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hyperthermia; Hyperthermia, Induced; Jumonji Domain-Containing Histone Demethylases; Lysine; Phototherapy | 2020 |
Estrogen Induces Selective Transcription of Caveolin1 Variants in Human Breast Cancer through Estrogen Responsive Element-Dependent Mechanisms.
Topics: Adult; Aged; Breast Neoplasms; Caveolin 1; Cell Line, Tumor; Estradiol; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Middle Aged; Receptors, Estrogen; Response Elements | 2020 |
PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
Topics: Acetylation; Amino Acid Sequence; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cell Line, Tumor; DNA Repair Enzymes; DNA Replication; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Models, Biological; MRE11 Homologue Protein; Mutation; p300-CBP Transcription Factors; Phosphorylation; Phosphoserine; Poly(ADP-ribose) Polymerase Inhibitors; Protein Binding | 2020 |
p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
Topics: Animals; Binding Sites; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Female; Fibroblasts; Genomic Instability; Humans; Lysine; Mice; Neuroblastoma; NF-kappa B p50 Subunit; Protein Domains; Protein Processing, Post-Translational; Serine; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |
Lysine-embedded cellulose-based nanosystem for efficient dual-delivery of chemotherapeutics in combination cancer therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cellulose; Curcumin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Humans; Lysine; Methotrexate; Nanoparticles; Tumor Cells, Cultured | 2020 |
Glyoxalase 1 expression analysis by immunohistochemistry in breast cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lactoylglutathione Lyase; Lysine; Neoplasm Recurrence, Local; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Progression-Free Survival; Receptor for Advanced Glycation End Products; Receptor, ErbB-2; Time Factors; Vascular Endothelial Growth Factor A | 2020 |
Broad genic repression domains signify enhanced silencing of oncogenes.
Topics: Breast Neoplasms; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatin; Conserved Sequence; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Nucleotide Motifs; Oncogenes; Regulatory Sequences, Nucleic Acid; RNA, Long Noncoding; Transcription Elongation, Genetic; Transcription Initiation, Genetic | 2020 |
Gold Nanoparticles Conjugated L-Lysine for Improving Cisplatin Delivery to Human Breast Cancer Cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cisplatin; Female; Gold; Humans; Lysine; Metal Nanoparticles | 2021 |
RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation.
Topics: Animals; Arginine; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Female; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Lysine; Mechanistic Target of Rapamycin Complex 1; Mice, Nude; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Ubiquitin-Protein Ligases; Ubiquitination | 2021 |
Antibody-drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells.
Topics: Antibodies; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Fluorescent Dyes; G2 Phase Cell Cycle Checkpoints; Humans; Imidazoles; Inhibitory Concentration 50; Lysine; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Nanomedicine; Nanoparticles; Paclitaxel; Receptor, ErbB-2; Trastuzumab | 2021 |
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.
Topics: Arginine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lysine; Methylation; Mitochondria; Neoplasm Metastasis; Organoids; Oxidative Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2021 |
Development and characterization of two novel
Topics: Amines; Amino Acid Sequence; Animals; Biological Transport; Breast Neoplasms; Cineradiography; Female; Gallium Radioisotopes; Humans; Lysine; Mice, Nude; Neoplasms, Experimental; Neuropeptide Y; Protein Binding; Radiopharmaceuticals; Staining and Labeling; Structure-Activity Relationship; Tissue Distribution | 2021 |
Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma.
Topics: Acetylation; Animals; Breast Neoplasms; Cell Line, Tumor; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice, Inbred BALB C; Mice, Nude; Microfilament Proteins; Neoplasm Metastasis; Neuropeptides; Nuclear Proteins; Oncogenes; Prognosis; Protein Serine-Threonine Kinases; Radiation Tolerance; RNA, Small Interfering; Transcription Factor 4; Transcriptional Activation; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2021 |
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.
Topics: Animals; Breast Neoplasms; Chromatin; Class I Phosphatidylinositol 3-Kinases; DNA-Binding Proteins; Epigenesis, Genetic; Female; HEK293 Cells; Hepatocyte Nuclear Factor 3-alpha; Humans; Lysine; MCF-7 Cells; Metabolic Networks and Pathways; Methyltransferases; Mice; Mice, Nude; Neoplasm Proteins; Pre-B-Cell Leukemia Transcription Factor 1; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Transcription, Genetic | 2017 |
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1.
Topics: Animals; Breast Neoplasms; Cell Movement; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Lung Neoplasms; Lysine; MCF-7 Cells; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Phosphorylation; Protein Stability; RNA Interference; Signal Transduction; Snail Family Transcription Factors; Time Factors; Transfection; Transforming Growth Factor beta1; Tumor Necrosis Factor alpha-Induced Protein 3; Tumor Necrosis Factor-alpha; Ubiquitination | 2017 |
A Heparin Binding Motif Rich in Arginine and Lysine is the Functional Domain of YKL-40.
Topics: Animals; Apoptosis; Arginine; Binding Sites; Breast Neoplasms; Cell Movement; Cell Proliferation; Chitinase-3-Like Protein 1; Female; Heparin; Humans; Lysine; Mice; Mice, SCID; Mutation; Neovascularization, Pathologic; Protein Binding; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Genotoxic effects of BnSP-6, a Lys-49 phospholipase A
Topics: Amino Acid Sequence; Animals; Bothrops; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Crotalid Venoms; DNA Damage; Female; Humans; Lysine; Phospholipases A2; Sequence Homology, Amino Acid; Snake Venoms | 2018 |
Regulation of Breast Cancer-Induced Osteoclastogenesis by MacroH2A1.2 Involving EZH2-Mediated H3K27me3.
Topics: Animals; Bone Resorption; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice, Inbred C57BL; Nucleosomes; Osteoclasts; Osteogenesis; Phosphorylation; Protein Binding; Protein-Lysine 6-Oxidase; Proto-Oncogene Proteins pp60(c-src) | 2018 |
Quantitative proteome and lysine succinylome analyses provide insights into metabolic regulation in breast cancer.
Topics: Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Computational Biology; Disease Progression; Female; Humans; Lysine; Middle Aged; Protein Processing, Post-Translational; Proteome; Proteomics; Succinic Acid; Tandem Mass Spectrometry | 2019 |
Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration.
Topics: Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Lysine; MCF-7 Cells; Methylation; Myeloid-Lymphoid Leukemia Protein; Protein Methyltransferases | 2018 |
Photosensitiser functionalised luminescent upconverting nanoparticles for efficient photodynamic therapy of breast cancer cells.
Topics: Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Endocytosis; Female; Fluorescent Dyes; Humans; Lysine; Nanoparticles; Photochemotherapy; Photosensitizing Agents; Rose Bengal; Singlet Oxygen | 2019 |
OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.
Topics: Adaptor Proteins, Signal Transducing; Animals; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; ErbB Receptors; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Metastasis; Neoplastic Stem Cells; Phenotype; Phosphoproteins; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sumoylation; Thiolester Hydrolases; Time Factors; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2019 |
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter.
Topics: Acetylation; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; Drug Resistance, Neoplasm; Humans; In Vitro Techniques; Lysine; MCF-7 Cells; Mice; Mutation; Neoplasm Transplantation; Peroxidase; Protein Structure, Quaternary; Reactive Oxygen Species; Superoxide Dismutase; Tamoxifen; Tumor Suppressor Proteins | 2019 |
Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Glucose; Humans; Lactic Acid; Lysine; Pancreatic Neoplasms; Polyphenols | 2019 |
HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells.
Topics: Acetylation; Benzamides; Breast Neoplasms; Down-Regulation; Enhancer Elements, Genetic; Female; Gene Knockdown Techniques; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Lysine; Neoplastic Stem Cells; Pyridines; Transcription Factors; Transcription, Genetic | 2019 |
Histone lysine trimethylation or acetylation can be modulated by phytoestrogen, estrogen or anti-HDAC in breast cancer cell lines.
Topics: Acetylation; Breast Neoplasms; Chromatin; DNA Methylation; Epigenesis, Genetic; Estrogens; Female; Gene Expression Regulation, Neoplastic; Glycine max; Histone Deacetylase Inhibitors; Histone Demethylases; Histones; Humans; Lysine; MCF-7 Cells; Phytoestrogens | 2013 |
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.
Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation | 2013 |
Prediction of BRCA1 germ-line mutation status in patients with breast cancer using histoprognosis grade, MS110, Lys27H3, vimentin, and KI67.
Topics: BRCA1 Protein; Breast Neoplasms; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Germ-Line Mutation; Histones; Humans; Immunohistochemistry; Ki-67 Antigen; Logistic Models; Lysine; Multivariate Analysis; Neoplasm Grading; Patient Selection; Phenotype; Predictive Value of Tests; Prognosis; Reproducibility of Results; Tissue Array Analysis; Vimentin | 2013 |
Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Line; Cell Movement; Epithelial Cells; Green Fluorescent Proteins; HEK293 Cells; Humans; Lysine; Mammary Glands, Human; MCF-7 Cells; Mice; Microscopy, Confocal; Mutation; rac1 GTP-Binding Protein; RNA Interference; Tight Junctions; TNF Receptor-Associated Factor 4; Ubiquitin-Protein Ligases; Ubiquitination | 2013 |
Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies.
Topics: Alkylation; Amino Acid Sequence; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 7; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Activation; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lysine; MCF-7 Cells; Mice; Mice, Inbred NOD; Mice, SCID; Protein Interaction Maps; Signal Transduction; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays | 2013 |
Specific expression of k63-linked ubiquitination of calmodulin-like protein 5 in breast cancer of premenopausal patients.
Topics: Adult; Aged; Breast Neoplasms; Calcium-Binding Proteins; Cell Nucleus; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Immunoblotting; Lysine; Middle Aged; Premenopause; Tumor Cells, Cultured; Ubiquitination | 2013 |
Should a BRCA2 stop codon human variant, usually considered a polymorphism, be classified as a predisposing mutation?
Topics: Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Genotype; Germ-Line Mutation; Humans; Lysine; Male; Middle Aged; Neoplasms; Polymorphism, Genetic | 2014 |
Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation.
Topics: Acetylation; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Chromatin Immunoprecipitation; Circular Dichroism; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; E2F1 Transcription Factor; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Histones; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Kaplan-Meier Estimate; Lysine; Middle Aged; Mutation; Prognosis; Proportional Hazards Models; Real-Time Polymerase Chain Reaction; Receptor Cross-Talk; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2014 |
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Chromatin; Co-Repressor Proteins; Crystallography, X-Ray; Disease-Free Survival; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Oncogenes; Prognosis; Protein Binding; Protein Conformation; Protein Structure, Tertiary; RNA Polymerase II; Substrate Specificity; Transcription Elongation, Genetic | 2014 |
Recognizing methylated histone variant H3.3 to prevent tumors.
Topics: Animals; Breast Neoplasms; Carrier Proteins; Female; Histones; Humans; Lysine; RNA Polymerase II; Transcription Elongation, Genetic | 2014 |
Statistical modeling of the drug load distribution on trastuzumab emtansine (Kadcyla), a lysine-linked antibody drug conjugate.
Topics: Ado-Trastuzumab Emtansine; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Chromatography, Liquid; Female; Humans; Immunoconjugates; Lysine; Maytansine; Models, Statistical; Molecular Structure; Receptor, ErbB-2; Structure-Activity Relationship; Tandem Mass Spectrometry; Tissue Distribution; Trastuzumab; Tumor Cells, Cultured | 2014 |
ZMYND11: an H3.3-specific reader of H3K36me3.
Topics: Animals; Breast Neoplasms; Carrier Proteins; Female; Histones; Humans; Lysine; RNA Polymerase II; Transcription Elongation, Genetic | 2014 |
RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.
Topics: Acetylation; Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Eukaryotic Initiation Factors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lysine; Mass Spectrometry; Molecular Sequence Data; Polyribosomes; Ribosomal Proteins; RNA Interference | 2014 |
The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes.
Topics: Amino Acid Motifs; Amino Acid Sequence; beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lysine; Lysosomes; Models, Biological; Molecular Sequence Data; Neoplasm Staging; Peptides; Phosphorylation; Phosphotyrosine; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases, Non-Receptor; Proteolysis; Receptor, ErbB-2; Signal Transduction; Structure-Activity Relationship; Substrate Specificity; Ubiquitination | 2014 |
Association of H3K9me3 and H3K27me3 repressive histone marks with breast cancer subtypes in the Nurses' Health Study.
Topics: Adult; Breast Neoplasms; Epidemiologic Studies; Estrogen Receptor alpha; Female; Histones; Humans; Life Style; Lysine; Methylation; Middle Aged; Multivariate Analysis; Receptor, ErbB-2; Receptors, Progesterone; Reproductive History; Risk Factors; United States | 2014 |
Cks1 proteasomal turnover is a predominant mode of regulation in breast cancer cells: role of key tyrosines and lysines.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cells, Cultured; Female; HEK293 Cells; HeLa Cells; Humans; Lysine; MCF-7 Cells; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Proteolysis; Tyrosine | 2015 |
Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Movement; Cell Proliferation; DNA Methylation; Enzyme Inhibitors; Female; Flow Cytometry; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunoenzyme Techniques; Lysine; Methyltransferases; Mice; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Reversibly crosslinked hyaluronic acid nanoparticles for active targeting and intelligent delivery of doxorubicin to drug resistant CD44+ human breast tumor xenografts.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Chemistry, Pharmaceutical; Cross-Linking Reagents; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Injections, Intravenous; Lysine; MCF-7 Cells; Mice, Nude; Molecular Targeted Therapy; Nanomedicine; Nanoparticles; Solubility; Technology, Pharmaceutical; Thioctic Acid; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT.
Topics: Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; Lysine; Membrane Proteins; Methylation; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Prognosis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Sesquiterpenes; Transcription Factor RelA; Urinary Bladder Neoplasms | 2015 |
Lysine triggered ratiometric conversion of dynamic to static excimer of a pyrene derivative: aggregation-induced emission, nanomolar detection and human breast cancer cell (MCF7) imaging.
Topics: Amination; Breast; Breast Neoplasms; Female; Fluorescent Dyes; Humans; Lysine; MCF-7 Cells; Microscopy, Fluorescence; Models, Molecular; Optical Imaging; Propanols; Pyrenes | 2015 |
Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Female; HSP70 Heat-Shock Proteins; Humans; Kaplan-Meier Estimate; Lysine; Methylation; Middle Aged; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Prognosis; Proportional Hazards Models; Protein Processing, Post-Translational | 2015 |
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
Topics: Adult; Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Heterozygote; Humans; Logistic Models; Lysine; Male; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Ovarian Neoplasms; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Risk Assessment; Risk Factors | 2016 |
ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Proliferation; DNA-Binding Proteins; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone Demethylases; Histones; Humans; Lysine; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Prognosis; Protein Binding; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2016 |
Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes.
Topics: Acetylation; Breast Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Histones; Humans; Lysine | 2016 |
Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Chromatin; Dual-Specificity Phosphatases; E1A-Associated p300 Protein; Epigenomics; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; Genetic Loci; Histones; Humans; Lysine; MCF-7 Cells; Neoplastic Stem Cells; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport | 2016 |
Oncofetal Epigenetic Bivalency in Breast Cancer Cells: H3K4 and H3K27 Tri-Methylation as a Biomarker for Phenotypic Plasticity.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Epithelial Cells; Female; Genes, Neoplasm; Histones; Human Embryonic Stem Cells; Humans; Lysine; Neoplastic Stem Cells; Phenotype; Promoter Regions, Genetic; Protein Processing, Post-Translational | 2016 |
A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; HeLa Cells; Humans; Lysine; MCF-7 Cells; Mice; Oncogene Proteins; Proteolysis; Proto-Oncogene Proteins c-myc; Sirtuin 2; Ubiquitination | 2016 |
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Mutation; Neoplastic Stem Cells; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2017 |
PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Cycle; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Transport; Proto-Oncogene Proteins c-akt; Retinoblastoma-Binding Protein 2; Subcellular Fractions; Substrate Specificity; Treatment Outcome | 2016 |
HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth.
Topics: Acetylation; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 6; Histone Deacetylases; HMGN2 Protein; Humans; Lysine; MCF-7 Cells; Mice; Neoplasm Metastasis; Neoplasm Transplantation; STAT5 Transcription Factor; Transcription, Genetic; Tumor Suppressor Proteins | 2016 |
Increased expression of the histone H3 lysine 4 methyltransferase MLL4 and the histone H3 lysine 27 demethylase UTX prolonging the overall survival of patients with glioblastoma and a methylated MGMT promoter.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Proliferation; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA-Binding Proteins; Glioblastoma; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methyltransferases; Nuclear Proteins; Prognosis; Retrospective Studies; Tumor Suppressor Proteins | 2017 |
Nonhemolytic Cell-Penetrating Peptides: Site Specific Introduction of Glutamine and Lysine Residues into the α-Helical Peptide Causes Deletion of Its Direct Membrane Disrupting Ability but Retention of Its Cell Penetrating Ability.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cations; Cell Membrane; Cell Survival; Cell-Penetrating Peptides; Drug Delivery Systems; Female; Glutamine; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Methotrexate; Mutation; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop.
Topics: Antigens, CD; Base Sequence; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Chromatin; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; MicroRNAs; Neoplasm Grading; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; RNA, Small Interfering; Transfection; Wound Healing | 2016 |
Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.
Topics: Animals; Apoptosis; Biocatalysis; Breast Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Kinesins; Loss of Function Mutation; Lysine; MCF-7 Cells; Mice, Nude; Mitosis; Protein Binding; Protein Stability; Signal Transduction; Spindle Apparatus; Spindle Poles; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Lysine; MCF-7 Cells; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplastic Stem Cells; Nuclear Proteins; RNA, Small Interfering; Signal Transduction; Survival Analysis; Twist-Related Protein 1; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
Acetylation Enhances the Promoting Role of AIB1 in Breast Cancer Cell Proliferation.
Topics: Acetylation; Breast Neoplasms; Cell Proliferation; Female; Gene Knockdown Techniques; Histone Acetyltransferases; Humans; Lysine; MCF-7 Cells; Nuclear Receptor Coactivator 3; Signal Transduction; Transfection | 2016 |
Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.
Topics: Antibodies; Breast Neoplasms; Cell Line, Tumor; Female; Flow Cytometry; Humans; Immunoconjugates; Lysine; Protein Domains; Protein Engineering; Receptor, ErbB-2; Recombinant Fusion Proteins; Rhodamines; Serum Albumin; Trastuzumab | 2016 |
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression.
Topics: Breast Neoplasms; Cell Line, Tumor; CRISPR-Cas Systems; Disease Progression; Evolution, Molecular; Female; Gene Knockout Techniques; HSP90 Heat-Shock Proteins; Humans; Lysine; Structure-Activity Relationship | 2017 |
The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Silencing; HEK293 Cells; Humans; Lysine; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Protein Binding; Protein Stability; Proteomics; Sirtuin 2; Snail Family Transcription Factors; Substrate Specificity | 2016 |
Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Female; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Prognosis; Receptors, Estrogen; Survival Analysis; Tumor Cells, Cultured; Young Adult | 2017 |
Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer.
Topics: beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; DNA Helicases; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Essential; Glycogen Synthase Kinase 3 beta; Histones; Humans; Lysine; Male; Methylation; Molecular Targeted Therapy; Neoplasms; NF-kappa B; Phosphorylation; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Stability; Proteolysis; PTEN Phosphohydrolase; Tumor Necrosis Factor-alpha; Ubiquitination | 2017 |
Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enhancer Elements, Genetic; Estradiol; Estrogen Receptor alpha; Female; GATA3 Transcription Factor; Gene Expression Regulation, Neoplastic; Genomics; Hepatocyte Nuclear Factor 3-alpha; Histones; Humans; Lysine; Methylation; Oncogenes; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Transcription, Genetic | 2017 |
Acetylation targets HSD17B4 for degradation via the CMA pathway in response to estrone.
Topics: Acetylation; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Movement; CREB-Binding Protein; Down-Regulation; Estrone; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Models, Biological; Mutation; Neoplasm Invasiveness; Peroxisomal Multifunctional Protein-2; Proteolysis; Sirtuin 3; Substrate Specificity | 2017 |
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Topics: Acetylation; Adenosine Triphosphate; Benzoquinones; Breast Neoplasms; Cells, Cultured; Collagen; Drug Combinations; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Immunoblotting; Immunoprecipitation; Indoles; Lactams, Macrocyclic; Laminin; Lysine; Matrix Metalloproteinase 2; Mutagenesis, Site-Directed; Neoplasm Invasiveness; p300-CBP Transcription Factors; Panobinostat; Protein Processing, Post-Translational; Proteoglycans; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.
Topics: Acetylation; Antigens, CD; Apoptosis; Blotting, Western; Breast Neoplasms; Cadherins; CARD Signaling Adaptor Proteins; Cells, Cultured; Chromatin Immunoprecipitation; CpG Islands; Cytoskeletal Proteins; Epigenesis, Genetic; Estrogen Receptor alpha; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histones; Humans; Kidney; Lysine; Methylation; Nucleosomes; Polymerase Chain Reaction; RNA, Small Interfering | 2008 |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors | 2008 |
Aspisol inhibits tumor growth and induces apoptosis in breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lysine; Mice; Proto-Oncogene Proteins c-bcl-2 | 2008 |
[Rhein lysinate induces apoptosis in breast cancer SK-Br-3 cells by inhibiting HER-2 signal pathway].
Topics: Anthraquinones; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Female; Humans; Inhibitory Concentration 50; Lysine; NF-kappa B; Receptor, ErbB-2; RNA, Messenger; Signal Transduction; Tumor Suppressor Protein p53 | 2008 |
Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Chromatin; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Fibrosarcoma; Glioblastoma; Histones; Humans; Immunoprecipitation; Lysine; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured | 2009 |
Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of Taxol in athymic mice.
Topics: Animals; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Inhibitory Concentration 50; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Time Factors; Xenograft Model Antitumor Assays | 2009 |
Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers.
Topics: Acetylation; Binding Sites; Blotting, Western; Breast Neoplasms; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histones; Humans; Immunohistochemistry; Kidney Neoplasms; Lysine; Male; Neoplasms; Nucleosomes; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Recombinant Proteins; Tissue Array Analysis; Urinary Bladder Neoplasms | 2009 |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-2 | 2009 |
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.
Topics: Amino Acid Substitution; Animals; Arginine; Aromatase Inhibitors; Breast Neoplasms; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Lysine; Mice; Mice, Nude; Mutation, Missense; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Prognosis; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Mapping of lysine monomethylation of linker histones in human breast and its cancer.
Topics: Aged; Breast; Breast Neoplasms; Female; Histones; Humans; Linear Models; Lysine; Methylation; Middle Aged; Peptide Fragments; Peptide Mapping; Proteomics; Tandem Mass Spectrometry | 2009 |
Screening for therapeutic targets of vorinostat by SILAC-based proteomic analysis in human breast cancer cells.
Topics: Acetylation; Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hydroxamic Acids; Immunoprecipitation; Isotope Labeling; Lysine; Mass Spectrometry; Molecular Sequence Data; Neoplasm Proteins; Peptides; Proteomics; Reproducibility of Results; Time Factors; Vorinostat | 2010 |
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; CCCTC-Binding Factor; Cell Line; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Estrogen Receptor alpha; Feedback, Physiological; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Immunoblotting; Lysine; Methylation; MicroRNAs; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; ras Proteins; Repressor Proteins; RNA Interference | 2010 |
Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors.
Topics: Acetylation; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Drug Resistance, Neoplasm; ErbB Receptors; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lysine; Mice; Mice, Inbred Strains; RNA, Small Interfering; Vorinostat | 2011 |
Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.
Topics: Arachidonic Acid; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type IV; Enzyme Inhibitors; Extracellular Matrix; Humans; Lysine; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitination | 2010 |
A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer.
Topics: Bayes Theorem; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epigenesis, Genetic; Estrogen Receptor alpha; Gene Regulatory Networks; Genomics; Histones; Humans; Lysine; Methylation; Models, Genetic; Reproducibility of Results; RNA Polymerase II; Tamoxifen; Time Factors | 2011 |
Relationship between lunasin's sequence and its inhibitory activity of histones H3 and H4 acetylation.
Topics: Acetylation; Amino Acid Sequence; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclins; Enzyme Inhibitors; Histone Acetyltransferases; Histones; Humans; Inhibitory Concentration 50; Lysine; Molecular Sequence Data; p300-CBP Transcription Factors; Peptide Fragments; Soybean Proteins; Structure-Activity Relationship | 2011 |
Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e.
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin D1; Epigenesis, Genetic; Female; Gene Silencing; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; MicroRNAs; Nuclear Proteins; Repressor Proteins | 2011 |
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Lysine; Multigene Family; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Elevated level of lysine 9-acetylated histone H3 at the MDR1 promoter in multidrug-resistant cells.
Topics: Acetylation; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Lysine; p300-CBP Transcription Factors; Promoter Regions, Genetic; RNA Interference | 2012 |
Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer.
Topics: Acetylation; Active Transport, Cell Nucleus; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CREB-Binding Protein; Cytoplasm; Estrogens; Exportin 1 Protein; Histone Deacetylase 6; Histone Deacetylases; Humans; Inhibitor of Apoptosis Proteins; Intracellular Space; Karyopherins; Lysine; Mice; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Survivin | 2012 |
RGD-conjugated PLA-PLL nanoparticles targeting to Bacp-37 breast cancer xenografts in vivo.
Topics: Biocompatible Materials; Breast Neoplasms; Female; Flow Cytometry; Humans; Lactic Acid; Lysine; Microscopy, Confocal; Nanoparticles; Oligopeptides; Polyesters; Polymers; Tissue Distribution; Xenograft Model Antitumor Assays | 2011 |
Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.
Topics: Armadillo Domain Proteins; beta Catenin; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Female; Gene Silencing; Humans; Lysine; Mutation; Neoplasm Invasiveness; Protein Binding; Transcription, Genetic; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination; Up-Regulation | 2012 |
Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers.
Topics: Acetylation; Amino Acid Sequence; Breast Neoplasms; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Humans; Lysine; Molecular Sequence Data; Protein Processing, Post-Translational; Tumor Cells, Cultured | 2012 |
Acetylation-dependent regulation of Skp2 function.
Topics: Acetylation; Amino Acid Sequence; Animals; Breast Neoplasms; Cadherins; Casein Kinase I; Cell Line, Tumor; Cell Movement; Cytoplasm; Disease Models, Animal; Humans; Lysine; Male; Mice; Molecular Sequence Data; p300-CBP Transcription Factors; Prostatic Neoplasms; Protein Processing, Post-Translational; Protein Sorting Signals; S-Phase Kinase-Associated Proteins; Sequence Alignment; Ubiquitination | 2012 |
Positron emission tomography imaging of vascular endothelial growth factor receptor expression with (61)Cu-labeled lysine-tagged VEGF121.
Topics: Animals; Breast Neoplasms; Copper Radioisotopes; Female; Humans; Lysine; Mice; Mice, Inbred BALB C; Molecular Imaging; Neovascularization, Pathologic; Positron-Emission Tomography; Radiometry; Receptors, Vascular Endothelial Growth Factor; Tissue Distribution; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2012 |
Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells.
Topics: Amino Acid Oxidoreductases; Animals; Breast Neoplasms; Carbohydrates; Catalytic Domain; Cell Line; Drosophila melanogaster; Glycosylation; Humans; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Neoplasm Metastasis; Peptides; Polysaccharides; Protein Folding; Protein Processing, Post-Translational; Quinones; Recombinant Proteins; Solvents | 2013 |
Sustained delivery of Her-2/neu antibody by TCPL delivery device using adult male rats as a model.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Calcium Phosphates; Capsules; Dose-Response Relationship, Drug; Drug Implants; Enzyme-Linked Immunosorbent Assay; Lysine; Male; Phosphates; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Reference Values; Saliva | 2003 |
PRELIMINARY BIOCHEMICAL STUDIES OF SOME EPSILON-SUBSTITUTED LYSINES.
Topics: Animals; Antimetabolites; Biochemical Phenomena; Biochemistry; Body Weight; Breast Neoplasms; Carboxy-Lyases; Diet; Humans; Lysine; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Pharmacology; Rats; Research; Toxicology | 1963 |
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Line, Tumor; Drug Design; Female; Fructose-Bisphosphate Aldolase; Humans; Immunotherapy; Integrin alphaVbeta3; Integrins; Ketones; Lysine; Melanoma; Models, Molecular; Molecular Mimicry; Oligopeptides; Protein Binding; Receptors, Vitronectin; Structure-Activity Relationship | 2004 |
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acid Substitution; Animals; Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cullin Proteins; DNA-Binding Proteins; Genes, Reporter; Humans; Hydroquinones; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Luciferases; Lysine; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Precipitin Tests; Protein Structure, Tertiary; Proteins; Serine; Substrate Specificity; Sulfoxides; Thiocyanates; Trans-Activators; Ubiquitin-Protein Ligases; Ubiquitins | 2004 |
Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth.
Topics: Alanine; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Histidine; Humans; Inhibitory Concentration 50; Lampreys; Lysine; Oligopeptides; Peptides; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Pyrrolidonecarboxylic Acid; Radioligand Assay | 2005 |
Development of magnetic resonance imaging contrast material for in vivo mapping of tissue transglutaminase activity.
Topics: alpha-2-Antiplasmin; Breast Neoplasms; Cell Line, Tumor; Contrast Media; Gadolinium DTPA; Humans; Lysine; Magnetic Resonance Imaging; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptide Fragments; Spheroids, Cellular; Substrate Specificity; Transglutaminases | 2005 |
Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins.
Topics: Breast Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Endodeoxyribonucleases; Epigenesis, Genetic; Female; Genome, Human; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methyl-CpG-Binding Protein 2; Methyltransferases; Repressor Proteins | 2006 |
Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.
Topics: Acetylation; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Estrogens; Histone Deacetylases; Humans; Lysine; Mutation; Protein Binding; Repressor Proteins; Transcription, Genetic | 2006 |
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Leucine; Lung Neoplasms; Lysine; Male; Membrane Potentials; Mice; Mice, SCID; Neoplasm Metastasis; Peptides; Phosphatidylserines; Prostate-Specific Antigen; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2006 |
Radiolabeled L-lysine for tumor imaging.
Topics: Adenocarcinoma; Animals; Breast; Breast Neoplasms; Chelating Agents; Chromatography, High Pressure Liquid; Chromatography, Paper; Chromatography, Thin Layer; Disease Models, Animal; Feasibility Studies; Female; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Radiometry; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Technetium Tc 99m Dimercaptosuccinic Acid; Tumor Cells, Cultured | 2006 |
Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity.
Topics: Breast Neoplasms; Female; Fibrinolysin; Humans; Lysine; Neoplasm Invasiveness; Plasminogen; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Up-Regulation; Urokinase-Type Plasminogen Activator | 2007 |
Carbonyl and oxidative stress in patients with breast cancer--is there a relation to the stage of the disease?
Topics: Blood Proteins; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Neoplasm Staging; Oxidation-Reduction; Oxidative Stress; Prognosis; Protein Carbonylation; Receptor, ErbB-2 | 2007 |
Mass spectrometric analysis of high-mobility group proteins and their post-translational modifications in normal and cancerous human breast tissues.
Topics: Amino Acid Sequence; Breast; Breast Neoplasms; Female; HMGA1a Protein; HMGA1b Protein; Humans; Lysine; Methylation; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry | 2007 |
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; Lysine; Male; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Telomerase | 2008 |
Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line; Chlorocebus aethiops; Down-Regulation; Endopeptidases; Hormones; Humans; Ligands; Lysine; Mutation; Phosphorylation; Promoter Regions, Genetic; Receptors, Progesterone; Sensitivity and Specificity; SUMO-1 Protein; Transcription, Genetic | 2007 |
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Histones; Humans; Lysine; Middle Aged; Ovarian Neoplasms; Pancreatic Neoplasms; Predictive Value of Tests; Prognosis; Treatment Failure; Treatment Outcome | 2008 |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?
Topics: Acetylation; Adenocarcinoma; Aged; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Nucleus; Chromatin Immunoprecipitation; Colorectal Neoplasms; Fatty Acid Synthases; Female; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Lysine; Male; Transcription, Genetic | 2007 |
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Topics: Adult; Amino Acid Substitution; BRCA1 Protein; Breast Neoplasms; Carrier Proteins; Chromosome Segregation; Conserved Sequence; DNA-Binding Proteins; Endodeoxyribonucleases; Evolution, Molecular; Fanconi Anemia Complementation Group Proteins; Female; Humans; Likelihood Functions; Lysine; Male; Methionine; Middle Aged; Models, Molecular; Mutation, Missense; Nuclear Proteins; Nucleic Acid Hybridization; Pedigree; Phosphopeptides; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; RNA Helicases | 2008 |
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms | 2008 |
MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells.
Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Molecular Sequence Data; Mucin-1; Pancreatic Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2008 |
Maillard products as biomarkers in cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cytoplasm; Female; Glycolysis; Humans; Immunohistochemistry; Lysine; Maillard Reaction; Neoplasm Invasiveness | 2008 |
Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line; Crystallography, X-Ray; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Conformation; Protein Methyltransferases; Sequence Alignment | 2008 |
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.
Topics: Acetylation; Alkaline Phosphatase; Biomarkers, Tumor; Breast Neoplasms; Cells, Cultured; Chromatin Immunoprecipitation; Colony-Forming Units Assay; CpG Islands; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Gene Silencing; Histones; Humans; Lung Neoplasms; Lysine; Male; Microarray Analysis; Microfilament Proteins; Phosphatidylinositol 3-Kinases; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2008 |
Constitutive and dynamic phosphorylation and acetylation sites on NUCKS, a hypermodified nuclear protein, studied by quantitative proteomics.
Topics: Acetylation; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; DNA; DNA Footprinting; G2 Phase; HeLa Cells; Humans; Lysine; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Proteomics | 2008 |
[Evaluation of the efficiency of the immune system after immunostimulation in patients with breast cancer].
Topics: Adult; BCG Vaccine; Breast Neoplasms; Complement System Proteins; Cyclophosphamide; Female; Fluorouracil; Humans; Immunization; Immunoglobulins; Levamisole; Lysine; Middle Aged; Muramidase; Properdin; Vincristine | 1983 |
Magnetic resonance spectroscopy and breast cancer.
Topics: Biopsy, Needle; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Choline; Creatine; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Magnetic Resonance Spectroscopy; Mammography; Phosphocreatine | 1998 |
Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Division; Eflornithine; Female; Humans; Indicators and Reagents; Kinetics; Lysine; Male; Melanoma; Mice; Mice, Nude; Molecular Structure; Polyamines; Prostatic Neoplasms; Spermidine; Spermine; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2000 |
In vitro capacity of various cyclooxygenase inhibitors to revert immune suppression caused by radiation therapy for breast cancer.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Ketoprofen; Lymphocyte Activation; Lysine; Meclofenamic Acid; Middle Aged; Phytohemagglutinins | 1990 |
Immunological specificities of lysine-rich histones from tumors.
Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Complement Fixation Tests; Female; Histones; Humans; Liver; Liver Neoplasms; Lysine; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Organ Specificity; Peptide Fragments; Phyllodes Tumor; Rabbits; Rats; Species Specificity; Thymus Gland | 1974 |
Immunosuppressive effects of L-asparaginase.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine | 1970 |
[Lysine-Vasopressin test for the diagnosis of breast cancer].
Topics: Adrenal Medulla; Breast Neoplasms; Female; Humans; Hydrocortisone; Lysine; Pituitary Gland; Pituitary-Adrenal Function Tests; Vasopressins | 1971 |
Occurrence of L-lysine dehydrogenase (LyDH) in human serum in normal and some pathological states.
Topics: Adolescent; Adult; Amino Acid Oxidoreductases; Breast Neoplasms; Female; Heart Diseases; Heart Failure; Humans; Kidney Neoplasms; Leukemia, Lymphoid; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Lysine; Male; Middle Aged; Multiple Myeloma; Myocardial Infarction; Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms | 1967 |
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Proteins; Female; Gastrointestinal Neoplasms; Glucose; Glycolysis; Leucine; Lung Neoplasms; Lysine; Neoplasm Metastasis; Perfusion; Stimulation, Chemical; Uterine Neoplasms; Valine | 1969 |