Page last updated: 2024-08-17

lysine and Benign Neoplasms

lysine has been researched along with Benign Neoplasms in 325 studies

Research

Studies (325)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (12.31)	18.7374
1990's	4 (1.23)	18.2507
2000's	49 (15.08)	29.6817
2010's	143 (44.00)	24.3611
2020's	89 (27.38)	2.80

Authors

Authors	Studies
Jung, M; Staudt, M	1
Bachmann, M; Brandt, F; Kopka, K; Laube, M; Löser, R; Pietzsch, HJ; Pietzsch, J; Ullrich, M; van den Hoff, J; Wodtke, R	1
Chen, ES; Lam, UTF	1
Jeon, HY; Pornour, M; Qi, J; Ryu, H	1
Geng, Y; Niu, JQ; Song, TQ; Wang, YF; Yang, G; Yuan, HF; Yuan, Y; Yun, HL; Zhang, XD; Zhao, LN; Zhao, M; Zheng, W	1
Abbasi, Y; Anbiyaee, O; Farzaneh, M; Ghaedrahmati, F; Gholami, E; Kuchaki, Z; Meybodi, SM; Rashid Sheykhahmad, F	1
Barceló, C; Javed, A; Malagraba, G; Rubio-Tomás, T; Yarmohammadi, M	1
Burchell, JM; Taylor-Papadimitriou, J	1
Kong, F; Ma, L; Tang, R; Wang, X; You, H; Zheng, K	1
Gu, MZ; Han, C; Li, ZR; Xu, X; Zhang, HL; Zhang, JH	1
Li, X; Nie, S; Song, Y; Wu, F; Wu, J; Yao, Y; Zhou, C	1
Ding, P; Feng, Y; Han, J; Jiang, M; Li, H; Liu, D; Lu, D; Ma, Z; Pan, M; Shao, C; Wang, J; Yan, X; Zhang, Y	1
Contreras, J; El-Sherif, AA; Froux, A; Martín-Hurtado, A; Mohamed, HT; Plaza-Menacho, I; Shehata, MA	1
Biggar, KK; Chopra, A; Willmore, WG	1
Chen, Y; Ma, L; Sun, Y; Yao, F; Yao, Y; Zhou, D	1
Barghout, SH; Barsyte-Lovejoy, D; Machado, RAC	1
Chen, M; Chen, X; Guo, Z; Liang, R; Tian, H; Wang, Z	1
Diao, W; Li, Y; Wang, J; Xu, S; Zheng, J	1
Castiello, C; Fiorentino, F; Mai, A; Rotili, D	1
Abu-Hanna, J; Anastasakis, E; Clapp, LH; Cohen, R; Eddama, MMR; Loizidou, M; Patel, JA	1
Bouleau, A; Chevaleyre, C; Dubois, S; Evans, MJ; Kereselidze, D; Kuhnast, B; Nozach, H; Richard, M; Specklin, S; Tran, VL; Truillet, C	1
Ding, L; Li, Y; Rao, GW; Ren, S; Zhang, W	1
Li, WH; Li, YM; Su, JY	1
Ambrosi, C; Baubec, T; Faller, WJ; Haarhuis, JHI; Kwesi-Maliepaard, EM; Liu, NQ; Malik, M; Molenaar, TM; Silva, J; van Leeuwen, F; van Welsem, T	1
Bartling, CRO; Bolding, JE; Davies, MJ; Gamon, LF; Hansen, TN; Martín-Gago, P; Olsen, CA; Rajabi, N; Strømgaard, K	1
De Martino, M; Vanpouille-Box, C	1
Azagra, A; Cobaleda, C	1
Cang, W; Chen, L; Gu, Y; Huang, L; Sun, P; Xiang, Y	1
Kundu, TK; Senapati, P; Singh, S	1
Abousaida, B; Carter, R; Derry, P; Gonzalez, VV; Kim, JBK; Krishnan, S; Liopo, AV; Mackeyev, Y; Rauta, PR; Sanders, K; Shohayeb, MA; Singh, P; Tezcan, O; Vijay, GV; Zahra, Y; Zubarev, ER	1
Cheng, Y; Deng, X; Jia, L; Li, S; Lian, S; Lu, Y; Wang, J; Zhai, S	1
Han, D; Lu, K	1
Mohri, K; Mukai, H; Nhat, KPH; Tagami, S; Wada, Y; Warashina, S; Watanabe, Y; Zouda, M	1
Chen, S; Cheng, K; Debnath, B; Han, H; Liang, B; Liu, Y; Lombard, DB; Neamati, N; Shu, K; Wang, Q; Wu, M; Yao, J; Yin, Y; Zheng, Y	1
Ranathunga, DTS; Torabifard, H	1
Mao, L; Wang, J; Wang, JH; Wen, Q; Wu, M; Yu, SC; Zhang, X	1
Chen, J; Chen, LJ; Li, CY; Liu, YJ; She, QS; Tao, F; Xu, XY; Yang, GJ; Zhong, XD; Zhu, MH	1
Chen, Y; Li, Z; Lin, C; Wang, G; Zhang, L; Zhang, T	1
Brown, MA; Crans, DC; Huesgen, L; Manganaro, JF; Padilla, A; Roess, DA	1
Agnew, DW; Bachmann, AS; Demireva, EY; Geerts, D; Schultz, CR; Sheldon, RD; Uhl, KL; Xie, H	1
Cheng, C; Deng, CM; He, Y; Li, A; Li, B; Li, SJ; Li, ZG; Liang, YY; Liao, L; Liu, JB; Liu, ZC; Wei, X; Xu, TY; Yang, H; Yang, J; Yu, XM; Zhang, GG; Zheng, CC; Zhu, YD	1
Leung, CH; Ma, DL; Song, YQ; Wang, W; Yang, GJ	1
Cai, NL; Lau, ATY; Wu, GQ; Wu, YY; Xu, YM	1
Bashtrykov, P; Bröhm, A; Bui, T; Jeltsch, A; Khella, MS; Pleiss, J; Schnee, P; Weirich, S	1
Abdullah, KG; Chatoff, A; Duan, T; Gao, J; Huang, T; Jin, C; Megill, E; Rich, JN; Snyder, NW; Wang, S; Wu, Q; Wu, X; Yang, K; Yuan, F; Yuan, H; Zhao, L; Zhao, Y; Zinn, PO	1
Ardana, A; Fletcher, NL; Ghosh, S; Huda, P; Thurecht, KJ; Williams, CC	1
Locasale, JW; Wei, F	1
Ko, CN; Li, D; Tian, T; Yang, C	1
Bao, L; Mou, Y; Qin, Y; Song, Y; Zhu, P	1
Abini-Agbomson, S; Armache, KJ; Burg, JM; Cheek, MA; De Ioannes, P; Ezell, RJ; Gloor, SL; Godínez-López, V; Gopinath, S; Gretarsson, K; Hickman, AR; Keogh, MC; Lee, R; Lu, C; Meiners, MJ; Nudler, E; Pasini, D; Rice, WJ; Rustichelli, S; Sun, L; Sun, ZW; Svetlov, V; Tamburri, S; Taylor, HF; Thomas, JF; Vaidya, A; Valencia-Sánchez, MI	1
Jadhav, HR; Jain, P; Manchanda, N; Wahi, A	1
Ju, Y; Li, Z; Pang, X; Ren, L; Sun, X; Wang, W; Wu, Z; Zhang, J; Zhang, Y; Zhao, Y; Zhao, Z; Zhou, Y	1
Prasad, SK; Sindhu, R; Supreeth, M; Thanmaya, M	1
Mao, F; Shi, YG	1
Chen, Y; Hu, J; Huang, C; Li, K; Li, X; Liu, A; Liu, L; Qiu, C; She, X; Song, D; Wan, K; Wang, G; Wang, J; Wu, Q; Xu, F; Yu, C	1
Eccleston, M; Herzog, M; Kotronoulas, A; Lobbens, A; Pamart, D; Rommelaere, G; Van den Ackerveken, P	1
Afenjar, A; Banka, S; Barish, S; Bellen, HJ; Blyth, M; Choufani, S; Costain, G; Cytrynbaum, C; Deshwar, AR; Haldeman-Englert, C; Hayes, I; Haynes, D; Huang, Y; Jobling, R; Kanca, O; Keren, B; Le Quesne Stabej, P; Mao, X; Mignot, C; Nil, Z; Prescott, T; Robin-Renaldo, F; Shinawi, M; Sisco, K; Tveten, K; Vøllo, A; Wangler, MF; Wegner, DJ; Weksberg, R; Wheeler, PG; Wilson, C; Yamamoto, S; Yap, P; Zhang, X; Zon, J	1
Chandnani, N; Gupta, I; Sarkar, K; Thakkar, V	1
Deng, J; Liao, X	1
Barroso-González, J; Bernstein, KA; de Vitis, M; García-Expósito, L; Ghosh, A; Hoang, SM; Lynskey, ML; Modesti, M; O'Sullivan, RJ; Roncaioli, JL; Sarkar, SN; Wallace, CT; Watkins, SC	1
Cornett, EM; Defossez, PA; Ferry, L; Rothbart, SB	1
Mi, YY; Song, NH; Wang, ZJ; Yuan, W; Zhang, LF; Zhang, W; Zhu, LJ; Zuo, L	1
Chandra, D; Gogada, R; Gundampati, RK; Hashmi, S; Jayanthi, S; Kumar, R; Lella, R; O'Malley, J; Suresh Kumar, TK; Wang, J; Yadav, N; Zhang, D	1
Adams, S; Archer, KE; Bai, C; Chari, R; Harvey, L; Keating, TA; Kovtun, Y; Laleau, R; Maloney, EK; Miller, ML; Reid, EE; Shizuka, M; Vitharana, D; Wilhelm, A; Yoder, NC	1
Chakraborty, D; Clarke, TL; Ji, F; Jin, J; Kaniskan, HÜ; Lawrence, MS; Ma, A; Mishra, S; Sadreyev, RI; Tang, R; Van Rechem, C; Whetstine, JR	1
Casanova, AG; Chuffart, F; Lukinović, V; Reynoird, N; Roth, GS	1
Gao, J; Gao, Y; Guo, L; Zhang, Y; Zhu, Z	1
Chen, J; Huang, K; Li, J; Li, R; Sun, R; Wang, Y; Xie, K; Yang, Q; Zhang, T; Zhang, Y; Zhao, Q; Zou, L	1
Butcher, D; Karim, B; Kobayashi, H; Liu, XF; Molitoris, BA; Nagaya, T; Okada, R; Pastan, I; Sandoval, R; Wei, J; Zhou, Q	1
Chen, R; Dou, J; Huang, J; Shu, Z; Wang, Y; Yu, J; Yuan, H; Zhang, H; Zhao, X; Zhou, A	1
Kosciuk, T; Lin, H	1
Cheng, L; Li, L; Liang, Y; Liu, M; Wang, R; Xia, J; Yue, L; Zhang, L; Zhang, N	1
Dent, SYR; Farria, AT; Koutelou, E	1
Cheng, H; Deng, W; Guo, Y; Jiang, P; Ning, W; Xu, H; Xue, Y	1
Huttner, D; Meller, A; Ohayon, S; Zrehen, A	1
Cheng, H; Du, Y; Gao, X; Li, X; Liu, Z; Liu, ZX; Yu, K; Zhang, Q; Zhao, Q	1
Bernard, BJ; Burkitt, K; Nakamura, Y; Nigam, N; Saloura, V; Vougiouklakis, T	1
Klonou, A; Markouli, M; Papavassiliou, AG; Piperi, C; Strepkos, D	1
Coller, HA; Corvalan, AZ	1
Hu, J; Li, S; Xia, X; Zhao, Q	1
Ahmed, Z; Bacolla, A; Cooper, DN; De-Paula, RB; Hegde, ML; Mitra, J; Mitra, S; Mort, M; Sengupta, S; Tainer, JA; Yang, C; Ye, Z	1
Gu, W; Kon, N; Li, H; Ou, Y; Rustgi, AK; Wang, SJ	1
Barshop, W; Bradley, LM; Finlay, D; Garcia, G; Gimple, RC; Hope, JL; Qiu, Z; Rantala, J; Rich, JN; Sangfelt, O; Shen, JZ; Spruck, C; Sun, D; Wohlschlegel, J; Wu, Q	1
Breau, RH; Cagiannos, I; Fergusson, DA; Flaman, A; Hutton, B; Lavallée, LT; Montroy, J; Morash, C; Tinmouth, A	1
Akther, M; Cho, DY; Choi, DK; Haque, ME; Jakaria, M; Kim, IS	1
Gong, X; Liu, F; Su, M	1
Chen, R; Hou, G; Huang, C; Jiang, B; Li, L; Liu, X; Lu, R; Wang, Y; Yang, Q; Yu, J; Zhao, X	1
Allis, CD; Chen, H; Chen, X; Lu, C; Majewski, J; Rajagopalan, KN; Weinberg, DN	1
Bauer, D; Hauser, S; Kopka, K; Laube, M; Löser, R; Neuber, C; Pietsch, M; Pietzsch, J; Rothe, R; Wodtke, J; Wodtke, R	1
Jeon, M; Kim, H; Lee, JM; Park, IG	1
Allegretti, M; Bellassai, N; Corradini, R; D'Agata, R; Giacomini, P; Huskens, J; Marti, A; Rozzi, A; Spoto, G; Volpi, S	1
Fujiki, K; Tanaka, K	1
Breau, RH; Cagiannos, I; Cnossen, S; Fergusson, DA; Fergusson, NA; Hutton, B; Lavallée, LT; Montroy, J; Morash, C	1
Dash, J; Pantoş, GD; Răsădean, DM; Sheng, B	1
Zaware, N; Zhou, MM	1
Ambrosio, S; Majello, B; Saccà, CD	1
Chau, LY; Chiang, MT; Hsu, FF; Lee, WH; Li, FA; Yeh, CT	1
Burke, KA; Conicella, AE; Fawzi, NL; Janke, AM; Mathews, KL; Mittal, J; Rahmanian, V; Seo, DH	1
Chen, R; Cui, N; Deng, R; Dou, J; Huang, J; Liu, T; Wang, J; Wang, Y; Yu, J; Zhang, H; Zhao, X	1
Dutra, LA; Heidenreich, D; Knapp, S; Man Chin, C; Santos, JLD; Silva, GDBD	1
Carpenter, BL; Chariou, PL; Ghiladi, RA; Gulati, NM; Hu, H; Masarapu, H; Patel, BK; Shukla, S; Steinmetz, NF	1
Ma, S; Zhang, F	1
Guo, YR; Hawke, D; He, J; Lee, JH; Li, XJ; Liu, K; Liu, R; Lu, Z; Lyu, J; Qian, X; Tan, L; Tao, YJ; Wang, Y; Xia, Y; Xing, D; Yang, P; Yin, Z; Zheng, Y	1
Chen, R; Garcia, JA; Nagati, J; Xu, M	1
Alabugin, IV; Basak, A; Bhattacharya, P; Campbell, A	1
Fan, YR; Huang, M; Huang, Y; Song, Y; Tian, DN; Wu, CX; Yang, XB	1
Alexander, C; Almarwani, B; Nguyen, HAT; Phambu, EN; Phambu, N; Sunda-Meya, A	1
Garza, N; Jin, VX; Kornblau, S; Li, T; Liu, Q	1
Bondy-Chorney, E; Denoncourt, A; Downey, M; Sai, Y	1
Boriack-Sjodin, PA; Chesworth, R; Copeland, RA; Duncan, KW; Harvey, DM; Janzen, WP; Kuntz, KW; Lampe, JW; Mitchell, LH; Morrison, MJ; Sadalge, D; Scott, MP; Swinger, KK; Wigle, TJ	1
Dai, Z; Gao, X; Locasale, JW; Mentch, SJ; Nichenametla, SN	1
Brasher, B; Fu, TM; Gan, W; Hauenstein, AV; Liang, AC; Liu, P; Schwerdtfeger, C; Su, S; Wei, W; Xu, M	1
Chan, DV; Hara, E; Iimori, M; Kitao, H; Maehara, Y; Watanabe, S	1
Brown, AM; Finkielstein, CV; Gotoh, T; Jiang, L; Kim, JK; Liu, J; Wisdom, EL; Zou, X	1
Bai, Y; Chen, T; Guo, X; Hu, R; Hu, Z; Huang, X; Jiang, S; Liu, H; Liu, X; Meng, X; Sun, SC; Wei, L; Xu, C; Xue, M; Yang, W; Zhou, P	1
Li, L; Li, R; Wang, Y	1
Cui, H; Dong, Z; Lei, Q; Li, L; Li, Q; Mao, J; Yang, J; Yang, L	1
Chen, L; Fang, Q; Li, W; Li, Z; Liang, W; Liu, N; Lu, F; Tian, Y; Wang, D; Xie, M; Yin, F; Zhao, H; Zhao, R	1
Allis, CD; Bagert, JD; Feng, L; Gao, J; Kundra, R; Lemiesz, AE; Muir, TW; Nacev, BA; Schultz, N; Soshnev, AA	1
Chen, Y; Chu, X; Han, D; Huang, M; Lei, Z; Li, Z; Liu, C; Wang, T	1
Chen, D; Chen, X; Li, H; Li, K; Liang, J; Liu, Y; Xu, X; Zeng, Q; Zeng, Y; Zhan, Y	1
Guo, J; Wei, W	1
Chen, R; Cui, N; Dou, J; Guo, Y; Huang, J; Liu, T; Wang, Y; Yang, Q; Yu, J; Zhang, H; Zhao, X	1
Chu, H; Felten, AE; Leamon, CP; Lu, YJ; Nelson, M; Parker, N; Reddy, JA; Shillingford, JM; Vaughn, JF; Vlahov, IR; Wang, EZ; Westrick, E; Xu, LC	1
Bros, C; Chan, PK; Kalkat, M; Kim, SS; Konforte, D; Oliveri, S; Pandyra, A; Penn, LZ; Raught, B; Sedivy, E; Wasylishen, AR	1
Li, Y; Liu, C; Xu, W; Zhao, S	1
Allen, JR; Chen, CY; Johnson, DL; Rohira, AD	1
Arinbasarova, AY; Berezov, TT; Lukasheva, EV; Medentzev, AG; Pokrovsky, VS; Sedakova, LA; Treshalina, HM	1
Babinski, DJ; Best, AM; Brekken, RA; Bruick, R; Chang, J; Dellinger, M; Easmon, J; Frantz, DE; Kumar, S; Martinez, ED; Peña-Llopis, S; Quinn, AM; Ruiz, J; Simeonov, A; Varghese, D; Wang, L; Xu, J	1
Gao, FY; Shen, JM; Tian, XZ; Xu, S; Yin, T	1
Guan, KL; Huang, W; Lei, QY; Lin, R; Lv, L; Xiong, Y; Zhao, D; Zhou, X	1
Chandrasekharan, P; Chuang, KH; He, T; Poh, Z; Raju, A; Robins, EG; Yang, CT	1
Li, GM	1
Chitalia, V; Costello, CE; Hartsough, EJ; Jiang, Y; Marquez, VE; Meyer, RD; Rahimi, N; Weinberg, J; Zhdanova, IV	1
Gu, Z; Jiang, W; Lai, K; Wu, Y	1
Díaz-Tejada, C; Grande-García, A; Lallous, N; Ramón-Maiques, S	1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW	1
Chun, YS; Park, JW; Shin, DH; Shin, SH; Yoon, H	1
Aguiar, M; Alečković, M; Arellano, M; Boggon, TJ; Britton, LM; Chen, H; Chen, J; Devi, N; Elf, S; Fan, J; Gaddh, M; Garcia, BA; Gu, TL; Hitosugi, T; Kaluz, S; Kang, HB; Kang, S; Kang, Y; Khoury, HJ; Khuri, FR; Lonial, S; Lonning, S; Mohammadi, M; Seo, JH; Shan, C; Tucker, M; Van Meir, EG; Xie, J	1
D'Argenio, V; Esposito, MV; Frisso, G; Gilder, JA; Salvatore, F	1
Choi, M; Kim, JE; Kim, W	1
Meslamani, J; Sanchez, R; Zhou, MM	1
Van Rechem, C; Whetstine, JR	1
Bailey, KM; Balagurunathan, Y; Cornnell, HH; Gillies, RJ; Hashim, AI; Ribeiro, MC; Wojtkowiak, JW	1
Chen, G; Jiao, H; Li, J; Mei, Z; Wang, W; Xu, Y	1
Chen, CY; Chen, HY; Chen, KB; Chen, KC	1
Bauer, A; Gerrits, B; Hoving, S; Kirschner, MW; Luchansky, SJ; Nagel, J; Schirle, M; Thomas, JR; Thompson, JW	1
Buettner, GR; Gius, D; Jung, B; Ozden, O; Park, SH; Song, HY; Vassilopoulos, A; Wagner, BA; Zhu, Y	1
Alfarano, MG; Jayaraman, P; Kidwai, S; Lu, G; Parikh, F; Sikora, AG; Svider, PF; Xiong, H	1
Barbacid, M; Beijersbergen, RL; Bernards, R; Drosten, M; García-Medina, R; Huang, S; Jacob, HK; Lechuga, CG; Simón-Carrasco, L; Sum, EY	1
Gao, C; Huang, F; Mao, Z; Yu, G; Yu, W	1
Fukami, K; Matsui, T; Yamagishi, S	1
Benes, CH; Black, JC; Burrowes, PD; Christiani, DC; Donado, C; Greninger, P; Ladd, B; Van Rechem, C; Whetstine, JR; Zhao, Y	1
McGrath, J; Trojer, P	1
Dent, SY; Farria, A; Li, W	1
Dasgupta, M; Dermawan, JK; Stark, GR; Willard, B	1
Dunne, K; Flashman, E; Hancock, RL; Kawamura, A; Walport, LJ	1
Cal, PM; Cordeiro, C; Frade, RF; Gois, PM	1
Hershey, JW; Mathews, MB	1
Balabanov, S; Bokemeyer, C; Braig, M; Hagel, C; Haralambieva, E; Hauber, J; Hermans-Borgmeyer, I; Nagel, CH; Neumann, M; Pällmann, N; Preukschas, M; Schweizer, M; Sievert, H; Wild, P	1
Ashkenazi, A; Chen, TT; Filvaroff, E; Jubb, A; Koeppen, H; Marsters, S; Merchant, M; Peng, J	1
Burchfield, JS; Li, Q; Wang, HY; Wang, RF	1
Chen, C; Chen, Q; Chen, R; Deng, R; Dou, J; Huang, J; Jin, H; Wang, Y; Xu, M; Yu, J; Zhang, H; Zhao, X; Zhu, C	1
Barsotti, AM; Rollins, RA; Ryskin, M	1
Ariyan, CE; Berger, MF; Borsu, L; Busam, KJ; Button, J; Cao, Z; Chen, Y; Chi, P; Fagin, JA; Gao, D; Hollmann, TJ; Hu, W; Ladanyi, M; Lailler, N; Landa, I; Lee, W; Merghoub, T; Murali, R; Murphy, DA; Obenauf, AC; Postow, MA; Ran, L; Sboner, A; Schwartz, GK; Scott, SN; Shah, RH; Shukla, S; Wang, L; Wiesner, T; Wong, EW; Zhang, QF; Zheng, D	1
Delgado-Andrade, C	1
Chen, H; Jiang, C; Li, X; Li, Y; Pan, T; Wang, Z; Xu, J; Zhang, J; Zhao, Z	1
D'Angiolella, V; Dianov, GL; Drobnitzky, N; Humphrey, TC; Jiang, Y; La Thangue, NB; Macaulay, VM; Markkanen, E; Mavrommati, I; Orlando, G; Pai, CC; Pfister, SX; Ryan, AJ; Sarkar, S; Verrill, C; Woodcock, M; Ying, S; Zalmas, LP	1
Kaypee, S; Kundu, TK; Mukherjee, D; Sethi, G; Shanmugam, MK; Sudarshan, D	1
Chen, Y; Hu, B; Ji, W; Liu, X; Mei, Z; Ouyang, G; Wang, J; Xiao, W; Zhang, D; Zhang, W; Zhou, C; Zhou, J	1
Aires, D; Axiak-Bechtel, SM; Bryan, JN; Cai, S; Douglas, J; Forrest, ML; Forrest, WC; Groer, C; Mohr, E; Selting, KA; Swarz, JA; Tate, DJ; Yang, Q; Zhang, T	1
Baba, T; Chiba, T; Ebina, M; Endo, T; Fukuda, T; Haratake, K; Kanemori, Y; Kigoshi, Y; Kim, J; Miyahara, H; Takebe, A; Tsuruta, F	1
Leng, Q; Mixson, AJ	1
Del Bufalo, D; Di Martile, M; Trisciuoglio, D	1
Cleveland, JL; Nakanishi, S	1
Kanoh, D; Kikuchi, S; Nakamura, H; Sakurai, Y; Sato, S; Suzuki, M	1
Liu, HM; Liu, Y; Ma, JL; Zheng, YC	1
Bizet, M; Brenner, C; Calonne, E; Cartron, PF; Dedeurwaerder, S; Defrance, M; Deplus, R; Fuks, F; Josseaux, E; Luciani, J; Ndlovu, M; Putmans, P	1
Dupéré-Richer, D; Ezponda, T; Licht, JD; Miller, WH; Nichol, JN	1
Alabugin, IV; Kaya, K; Nogues, JC; Rojas, JC; Roy, S; Sokolikj, Z; Zorio, DA	1
Giaccia, AJ	1
Carlson, SM; Gozani, O	1
Dohmae, N; Hamamoto, R; Matsuo, Y; Nakakido, M; Nakamura, Y; Simone, C; Suzuki, T; Tsurita, G; Watanabe, T; Yoshioka, Y	1
Encarnación-Guevara, S; Gil, J; Ramírez-Torres, A	1
Taniguchi, Y	1
Jiang, L; Mao, H; Wang, Y; Xue, Z; Zhu, D	1
Esteller, M; Pérez-Salvia, M	1
Bazarov, N; Celik, A; Cigdem, S; Gunduz, E; Kahraman, B; Kaya, T; Toker, AS	1
Filippakopoulos, P; Fujisawa, T	1
Dwane, L; Gallagher, WM; Ní Chonghaile, T; O'Connor, DP	1
Chakravarti, D; Chen, JR; Chen, P; Deng, P; DePinho, RA; Dey, P; Lan, Z; Li, J; Liang, X; Liao, W; Lu, X; Navone, NM; Shah, S; Shang, X; Spring, DJ; Tang, M; Troncoso, P; Wang, G; Wang, YA; Zhang, J; Zhao, D	1
Anselmi, F; Basile, G; Incarnato, D; Krepelova, A; Maldotti, M; Neri, F; Oliviero, S; Parlato, C; Rapelli, S	1
Basu, M; Chakrabarti, P; Das, C; Khan, MW	1
Champagne, KS; Gozani, O; Hom, RA; Hung, T; Kuo, AJ; Kutateladze, TG; Li, G; Lin, H; Peña, PV; Subach, OM; Verkhusha, VV; Wong, RP; Zhao, R	1
Klose, RJ; Ng, SS; Oppermann, U; Yue, WW	1
Falke, JJ; Landgraf, KE; Pilling, C	1
Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J	1
Fujisaki, Y; Horii, Y; Nagai, K; Shen, J	1
Hu, L; Qi, C; Zhu, YJ; Zhu, YT	1
La Thangue, NB; Stimson, L	1
Allis, CD; Cook, RG; Frierson, HF; Fujita, M; Fukusato, T; Iizuka, M; Mizzen, CA; Smith, MM; Takahashi, Y	1
Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K	1
Clerkin, K; Liang, JF; Shah, K; Tu, Z; Volk, M	1
Alabugin, IV; Ben, C; Breiner, B; Copland, JA; Kovalenko, SV; LeGrand, SN; Sang, QX; Singh, M; Strouse, GF; Yang, WY	1
Abraham, RT; Aslanian, A; Brognard, J; Coughlin, C; Dolled-Filhart, M; Hunter, T; Manning, G; You, Z; Zhang, YW	1
Hauser, AT; Heinke, R; Jung, M; Sippl, W; Spannhoff, A	1
Dubrot, J; Martinez-Forero, I; Melero, I; Palazon, A; Rouzaut, A	1
Bazan, F; Dixit, VM; Dornan, D; Eastham-Anderson, J; Ferrando, R; French, DM; Huang, DC; Huang, X; Lill, JR; Liu, J; Maecker, H; O'Rourke, K; Schwickart, M; Yue, P	1
Alekseev, SB; Shevchenko, AA; Smirnova, IP	1
Berger, SL; Chuikov, S; Dorsey, J; Huang, J; Jenuwein, T; Reinberg, D; Zhang, X	1
Füllgrabe, J; Hajji, N; Hermanson, O; Joseph, B; Vlachos, P; Wallenborg, K	1
Bergmann, A; Bolduc, C; Buff, E; Chen, Z; Davuluri, R; Gupta, R; Hariharan, IK; Herz, HM; Madden, LD; Shilatifard, A	1
Lin, HK; Yang, WL; Zhang, X	1
Akbarian, S; Hock, H; Huang, HS; Mostoslavsky, R; Qin, J; Van Buren, D; Zhong, L	1
Baek, SH; Binda, O; Choi, HJ; Gozani, O; Hwang, D; Kim, B; Kim, IS; Kim, JH; Kim, JY; Kim, KI; Kim, M; Kim, Y; Lee, H; Lee, JM; Lee, JS; Semenza, GL; Seo, SB; Shin, HJ	1
Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW	1
Abbasi, M; Berthiaume, LG; Lavasanifar, A; Uludağ, H; Weinfeld, M	1
Chen, HW; Gemo, AT; Kalashnikova, EV; Revenko, AS; Zou, JX	1
Allis, CD; Duncan, EM	1
Lu, T; Stark, GR; Wang, Y	1
Hübner, MR; Spector, DL	1
Ahn, WS; Baek, KH; Lee, EJ; Lee, HJ; Ramakrishna, S; Suresh, B	1
Boyd, BJ; Kaminskas, LM; Kelly, BD; McLeod, VM; Owen, DJ; Porter, CJ; Sberna, G	1
Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Raj, BS; Tate, RJ; Tetley, L	1
Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Tate, RJ; Tetley, L	1
Abbasi, M; Aliabadi, HM; Doillon, C; Kaur, K; Lai, R; Lavasanifar, A; Moase, EH; Uludağ, H	1
Jaramillo-Lambert, AN; Lee, NH; Li, Y; Williams, R; Yang, Y; Zhu, W	1
Dwarakanath, BS; Ganguli, M; Jiang, Y; Kalra, N; Khanduri, R; Langel, U; Mann, A; Naik, R; Shukla, V; Singh, AK; Thakur, G	1
Wolf, DH	1
Peng, L; Seto, E	1
Atadja, P; Dai, J; Gu, J; Li, E; Li, L; Lu, C; Luo, X; Wang, L; Zhang, H; Zhao, K; Zhou, S; Zhu, J	1
Raines, RT; Sundlass, NK	1
Beland, FA; Koturbash, I; Pogribny, IP; Simpson, NE	1
Jang, H; Lee, SJ; Park, C	1
Richon, VM	1
Lee, JH; Marks, PA	1
Abbruzzese, A; Caraglia, M; Marra, M; Park, MH; Wolff, EC	1
Seto, E; Telles, E	1
Huang, C; Li, J; Liu, J; Wu, XR; Yu, J; Yu, Y; Zhang, D	1
Duan, Y; Liu, P; Sun, Y; Yu, H; Zhu, M	1
Becker, A; Chandra, P; Dittrich, T; Klusmann, JH; Lippka, Y; Reinhardt, D; Selvakumar, D; Thakur, BK; Welte, K	1
Decarlo, D; Hadden, MK	1
Ikegami, D; Kim, YJ; Niwa, T; Takeshima, H; Ushijima, T; Wakabayashi, M	1
Chen, S; Liu, Y; Sun, FL; Wang, DL; Zhao, L	1
Black, JC; Whetstine, JR	1
Gozani, O; Hammell, M; Joshua-Tor, L; Kuo, A; McCombie, WR; Mills, AA; Paul, S; Schalch, T; Vogel, H	1
Chou, ST; Kahn, JD; Leng, Q; Mixson, AJ; Scaria, P; Tricoli, LJ; Woodle, M	1
Douvlis, Z	1
Hirohashi, S; Koizume, S; Sekiya, T; Shiraishi, M; Tachibana, K	1
Boehncke, WH; Elliott, PJ; Zollner, TM	1
GREENBERG, DM; OLSON, ME; RABINOVITZ, M	1
ANDERSON, DC; BUSCH, H; DAVIS, JR	2
LEACH, FR	1
DAVIS, JR; MORRIS, RN	1
BUSCH, H; HNILICA, LS; TAYLOR, CW	1
BUSCH, H; HNILICA, LS; MAVIOGLU, H; STEELE, WJ; TAYLOR, CW	1
BUSCH, H; STEELE, WJ	1
GENTY, N; MELONI, GA; VENDRELY, R	1
CHRISTENSEN, HN	1
HOLLINSHEAD, AC	1
MCQUEEN, JD; MEGO, JL	2
FARAONI, H; FROMM, GA; HECKER, E; NAJENSON, H	1
KRISHNA, G	1
Hahm, KS; Lee, DG; Park, Y	1
Aratani, Y; Furuhata, A; Kawai, Y; Toyokuni, S; Uchida, K	1
Yang, XJ	1
Albiez, H; Cremer, C; Cremer, M; Cremer, T; Stein, S; Wagler, B; Zinner, R	1
Kentsis, A; Miller, F; Osman, R; Pan, ZQ	1
Ahn, N; Ballestar, E; Boix-Chornet, M; Bonaldi, T; Calasanz, MJ; Caldas, C; Calvo, E; Cano, A; Colomer, D; Espada, J; Esteller, M; Fraga, MF; Haydon, C; Imhof, A; Iyer, NG; Jenuwein, T; Lopez, JA; Pérez-Rosado, A; Petrie, K; Piris, MA; Ropero, S; Schotta, G; Villar-Garea, A	1
Hoekman, K; Niessen, HW; Schalkwijk, CG; van Heijst, JW	1
Berndorff, D; Borkowski, S; Cyr, JE; Dinkelborg, LM; Friebe, M; Hilger, CS; Rother, A; Sieger, S; Viti, F	1
Clement, PM; Johansson, HE; Park, MH; Wolff, EC	1
Kroetz, MB	1
Akimoto, N; Hashida, M; Kawakami, S; Niidome, T; Okuda, T; Yamashita, F	1
Bernard, B; Bijster, M; de Jong, M; Forrer, F; Krenning, EP; Rolleman, EJ; Valkema, R; Vermeij, M	1
Fischer, PM; Heery, DM	1
Ben-Shushan, E; Bergman, Y; Cedar, H; Eden, E; Farkash, S; Hecht, M; Keshet, I; Reubinoff, BE; Schlesinger, Y; Simon, I; Straussman, R; Yakhini, Z; Zimmerman, J	1
Ambulos, N; Cambell, P; Goldgeier, L; Leng, Q; Mixson, AJ; Zhu, J	1
Eisenman, RN; Secombe, J	1
Reinberg, D; Sternglanz, R; Vaquero, A	1
Shi, Y	1
Li, K; Teng, LJ	1
Morrison, Z; Wiencke, JK; Yeh, RF; Zheng, S	1
Horinouchi, S; Shimazu, T; Yoshida, M	1
Ashworth, A; Barford, D; Hofmann, K; Komander, D; Lord, CJ; Scheel, H; Swift, S	1
Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ	1
Baert, JL; de Launoit, Y; Degerny, C; Wohlkonig, A	1
Ahmed, S; Boumber, Y; Haddad, BR; Issa, JP; Kondo, Y; Sekido, Y; Shen, L	1
Brown, RR	1
Tabor, CW; Tabor, H	1
Devoghel, JC	1
Szent-Györgyi, A	1
Tisdale, MJ	1
Brouckaert, P; Fiers, W; Takahashi, N	1
Gebbink, MF; Reijerkerk, A; Voest, EE	1
Allis, CD; Rice, JC	1
Dyson, MH; Mahadevan, LC; Rose, S	1
Ballario, P; Filetici, P; P, O	1
Carrasquillo, JA; Jeong, HJ; Kao, CH; Kim, MK; Kobayashi, H; Paik, CH; Paik, DS; Pie, JE; Waldmann, TA; Yao, Z	1
Mukhopadhyay, T; Nakamura, S; Roth, JA	1
Martino, G; Ventafridda, V	1
Bojan, O; Kiricuta, I	1
Ax, W; Bauer, HW	1
Hempel, K; Lange, HW; Löwer, R	1
Anderson, RL; Hahn, GM; Kapp, DS; Krag, DN; Rice, GC; van Kersen, I; Woo, SY	1
Cacciatore, L; Fabris, N; Lingetti, M; Mocchegiani, E; Talarico, M	1
Hahn, GM; Kapp, DS; Rice, GC; Woo, SY	1
Abergel, A; Amiot, JF; Babinet, P; Boule, D; Glowinski, J; Hardy, F; Mechali, D; Palacci, JH; Pellerin, M; Wingtin, LN	1
Farcot, JM; Laugner, B; Muller, A; Thiébaut, JB	1
Gabrielli, F; Tsugita, A	1
Brennan, MF; Burt, ME; Gorschboth, CM; Norton, JA; Wesley, RA	1
Le Grignou, P; Michelet, FX; Pinsolle, J	1
Laki, K	1
Eisen, HN	1
Al-Sarraf, M; Belamaric, J; Cejka, J; Kithier, K; Peterson, WD; Poulik, MD; Vaitkevicius, VK	1
Bottici, R; Ferrucci, A; Taddeucci, E	1
Berke, G; Stulting, RD	1
Balhorn, M; Balhorn, R; Chalkley, R; Morris, HP	1
Hersh, EM; Ohno, R	1
Bürgi, W; Schärer, HU	1
ROZHEK, IS	1
PUSHKAR, LN	1

Reviews

99 review(s) available for lysine and Benign Neoplasms

Article	Year
Molecular mechanisms in governing genomic stability and tumor suppression by the SETD2 H3K36 methyltransferase. The international journal of biochemistry & cell biology, 2022, Volume: 144 Topics: Animals; Carcinogenesis; Chromatin; Genomic Instability; Histones; Humans; Lysine; Mammals; Methylation; Neoplasms	2022
Emerging roles of JMJD3 in cancer. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022, Volume: 24, Issue:7 Topics: Apoptosis; Female; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Neoplasms	2022
The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update. Biomolecules, 2022, 03-17, Volume: 12, Issue:3 Topics: Chromatin; Histone Demethylases; Histones; Humans; Lysine; Neoplasms	2022
Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer. Cells, 2022, 03-25, Volume: 11, Issue:7 Topics: Animals; Epigenesis, Genetic; Histone Demethylases; Histone Methyltransferases; Histones; Humans; Lysine; Neoplasms; Polycomb-Group Proteins	2022
Regulation of epithelial-mesenchymal transition by protein lysine acetylation. Cell communication and signaling : CCS, 2022, 04-28, Volume: 20, Issue:1 Topics: Acetylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Histones; Humans; Lysine; Neoplasms	2022
Promising natural lysine specific demethylase 1 inhibitors for cancer treatment: advances and outlooks. Chinese journal of natural medicines, 2022, Volume: 20, Issue:4 Topics: Antineoplastic Agents; Enzyme Inhibitors; Histone Demethylases; Humans; Lysine; Neoplasms	2022
Lysine Acetylation/Deacetylation Modification of Immune-Related Molecules in Cancer Immunotherapy. Frontiers in immunology, 2022, Volume: 13 Topics: Acetylation; Humans; Immunotherapy; Lysine; Neoplasms; Protein Processing, Post-Translational	2022
Monoubiquitination in Homeostasis and Cancer. International journal of molecular sciences, 2022, May-25, Volume: 23, Issue:11 Topics: Homeostasis; Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Ubiquitin; Ubiquitination	2022
Chemical biology and pharmacology of histone lysine methylation inhibitors. Biochimica et biophysica acta. Gene regulatory mechanisms, 2022, Volume: 1865, Issue:6 Topics: Biology; Epigenesis, Genetic; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational	2022
Targeting histone demethylases as a potential cancer therapy (Review). International journal of oncology, 2022, Volume: 61, Issue:3 Topics: Histone Demethylases; Histones; Humans; Lysine; Methylation; Neoplasms	2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5. Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14 Topics: Humans; Lysine; Neoplasms; Peptides; Sirtuins; Structure-Activity Relationship	2022
Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature. Clinical epigenetics, 2022, 08-01, Volume: 14, Issue:1 Topics: DNA Methylation; Epigenesis, Genetic; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms	2022
Protein Lysine Methyltransferases Inhibitors. Current medicinal chemistry, 2023, Volume: 30, Issue:27 Topics: Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methyltransferases; Neoplasms; Protein Processing, Post-Translational	2023
NSD2 as a Promising Target in Hematological Disorders. International journal of molecular sciences, 2022, Sep-21, Volume: 23, Issue:19 Topics: Epigenesis, Genetic; Hematologic Diseases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Neoplasms; Repressor Proteins	2022
Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression. International journal of molecular sciences, 2022, Oct-08, Volume: 23, Issue:19 Topics: Histones; Humans; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Lactic Acid; Lysine; Neoplasms; Tumor Microenvironment; Waste Products	2022
Metabolic Regulation of Lysine Acetylation: Implications in Cancer. Sub-cellular biochemistry, 2022, Volume: 100 Topics: Acetyl Coenzyme A; Acetylation; Humans; Lysine; NAD; Neoplasms; Protein Processing, Post-Translational	2022
A review of the mechanism of succinylation in cancer. Medicine, 2022, Nov-11, Volume: 101, Issue:45 Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Acid	2022
Beyond metabolic waste: lysine lactylation and its potential roles in cancer progression and cell fate determination. Cellular oncology (Dordrecht), 2023, Volume: 46, Issue:3 Topics: Epigenesis, Genetic; Glycolysis; Humans; Lactic Acid; Lysine; Neoplasms	2023
The role of lysine-specific demethylase 6A (KDM6A) in tumorigenesis and its therapeutic potentials in cancer therapy. Bioorganic chemistry, 2023, Volume: 133 Topics: Carcinogenesis; Histone Demethylases; Histones; Humans; Lysine; Neoplasms	2023
Development of JmjC-domain-containing histone demethylase (KDM2-7) inhibitors for cancer therapy. Drug discovery today, 2023, Volume: 28, Issue:5 Topics: Chromatin; Histone Demethylases; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms	2023
Targeting Epigenetic Changes Mediated by Members of the SMYD Family of Lysine Methyltransferases. Molecules (Basel, Switzerland), 2023, Feb-20, Volume: 28, Issue:4 Topics: DNA-Binding Proteins; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Neoplasms; Transcription Factors	2023
The role and prospect of lysine-specific demethylases in cancer chemoresistance. Medicinal research reviews, 2023, Volume: 43, Issue:5 Topics: Drug Resistance, Neoplasm; Histone Demethylases; Histones; Humans; Lysine; Neoplasms	2023
Prospect of targeting lysine methyltransferase NSD3 for tumor therapy. Pharmacological research, 2023, Volume: 194 Topics: Humans; Lysine; Neoplasms	2023
Targeting LSD1 in tumor immunotherapy: rationale, challenges and potential. Frontiers in immunology, 2023, Volume: 14 Topics: Histone Demethylases; Histones; Humans; Immunotherapy; Lysine; Neoplasms; Tumor Microenvironment	2023
Targeting the epigenetic reader "BET" as a therapeutic strategy for cancer. Bioorganic chemistry, 2023, Volume: 140 Topics: Bromodomain Containing Proteins; Chromatin; Epigenesis, Genetic; Histones; Humans; Lysine; Neoplasms	2023
Shuttle between arginine and lysine: influence on cancer immunonutrition. Amino acids, 2023, Volume: 55, Issue:11 Topics: Amino Acids; Arginine; Diet; Immunonutrition Diet; Lysine; Neoplasms	2023
Targeting the LSD1/KDM1 Family of Lysine Demethylases in Cancer and Other Human Diseases. Advances in experimental medicine and biology, 2023, Volume: 1433 Topics: Histone Demethylases; Histones; Humans; Lysine; Neoplasms	2023
Epigenetic regulation of enhancer of zeste homolog 2 (EZH2) -Yin Yang 1 (YY1) axis in cancer. Pathology, research and practice, 2023, Volume: 251 Topics: Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Histones; Humans; Lysine; Neoplasms; Polycomb Repressive Complex 2; Yin-Yang; YY1 Transcription Factor	2023
Lysine Methylation Regulators Moonlighting outside the Epigenome. Molecular cell, 2019, 09-19, Volume: 75, Issue:6 Topics: Animals; Epigenome; Humans; Lysine; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Signal Transduction	2019
Lysine Methyltransferases Signaling: Histones are Just the Tip of the Iceberg. Current protein & peptide science, 2020, Volume: 21, Issue:7 Topics: Chromosomal Proteins, Non-Histone; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction	2020
N-Myristoyltransferase as a Glycine and Lysine Myristoyltransferase in Cancer, Immunity, and Infections. ACS chemical biology, 2020, 07-17, Volume: 15, Issue:7 Topics: Acyltransferases; Animals; Communicable Diseases; Enzyme Inhibitors; Glycine; Humans; Immunity, Innate; Lysine; Neoplasms; Protein Processing, Post-Translational; Proteins	2020
Complex functions of Gcn5 and Pcaf in development and disease. Biochimica et biophysica acta. Gene regulatory mechanisms, 2021, Volume: 1864, Issue:2 Topics: Acetylation; Adaptive Immunity; Animals; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Embryonic Development; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Immunity, Innate; Lysine; Mice; Mice, Transgenic; Mutation; Neoplasms; p300-CBP Transcription Factors	2021
Clinicopathologic significance of protein lysine methyltransferases in cancer. Clinical epigenetics, 2020, 10-13, Volume: 12, Issue:1 Topics: Adolescent; Adult; Clinical Trials as Topic; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenomics; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Lysine; Neoplasm Staging; Neoplasms; Survival Analysis; Young Adult	2020
Histone Methyltransferase SETDB1: A Common Denominator of Tumorigenesis with Therapeutic Potential. Cancer research, 2021, 02-01, Volume: 81, Issue:3 Topics: Carcinogenesis; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic	2021
Methylation of histone 4's lysine 20: a critical analysis of the state of the field. Physiological genomics, 2021, 01-01, Volume: 53, Issue:1 Topics: Animals; Cell Cycle; Embryonic Development; Histones; Humans; Lysine; Methylation; Neoplasms	2021
The GCN5: its biological functions and therapeutic potentials. Clinical science (London, England : 1979), 2021, 01-15, Volume: 135, Issue:1 Topics: Acetylation; Animals; Antineoplastic Agents; Chromatin Assembly and Disassembly; Enzyme Inhibitors; Epigenesis, Genetic; Histone Acetyltransferases; Histones; Humans; Lysine; Molecular Targeted Therapy; Neoplasms; Protein Domains; Protein Processing, Post-Translational; Structure-Activity Relationship; Substrate Specificity	2021
An update on the emerging approaches for histone deacetylase (HDAC) inhibitor drug discovery and future perspectives. Expert opinion on drug discovery, 2021, Volume: 16, Issue:7 Topics: Drug Discovery; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Neoplasms	2021
Coordinated methyl readers: Functional communications in cancer. Seminars in cancer biology, 2022, Volume: 83 Topics: Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms	2022
Biomolecular labeling based on lysine-clickable 6π-azaelectrocyclization toward innovative cancer theranostics. Bioorganic & medicinal chemistry, 2021, 07-15, Volume: 42 Topics: Animals; Antineoplastic Agents; Azides; Click Chemistry; Cyclization; Dose-Response Relationship, Drug; Humans; Lysine; Mice; Molecular Structure; Neoplasms; Positron-Emission Tomography; Structure-Activity Relationship; Theranostic Nanomedicine	2021
The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis. Transfusion medicine reviews, 2017, Volume: 31, Issue:3 Topics: Adult; Aminocaproic Acid; Blood Loss, Surgical; Blood Transfusion; Erythrocyte Transfusion; Humans; Lysine; Neoplasms; Patient Safety; Platelet Transfusion; Randomized Controlled Trials as Topic; Tranexamic Acid; Treatment Outcome; Venous Thrombosis	2017
Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation. Current opinion in chemical biology, 2017, Volume: 39 Topics: Epigenesis, Genetic; Genomics; Humans; Inflammation; Lysine; Neoplasms	2017
Epigenetic regulation of epithelial to mesenchymal transition by the Lysine-specific demethylase LSD1/KDM1A. Biochimica et biophysica acta. Gene regulatory mechanisms, 2017, Volume: 1860, Issue:9 Topics: Cell Movement; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Histone Demethylases; Humans; Lysine; Neoplasms	2017
Disrupting Acetyl-lysine Interactions: Recent Advance in the Development of BET Inhibitors. Current drug targets, 2018, Volume: 19, Issue:10 Topics: Acetylation; Animals; Antineoplastic Agents; Cell Cycle Proteins; Drug Development; Histones; Humans; Lysine; Models, Molecular; Neoplasms; Nuclear Proteins; Protein Conformation; Protein Processing, Post-Translational; Proteins; Structure-Activity Relationship; Transcription Factors	2018
Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy. Molecular pharmaceutics, 2018, 03-05, Volume: 15, Issue:3 Topics: Antibiotics, Antineoplastic; Cyclization; DNA Damage; DNA, Neoplasm; Enediynes; Humans; Light; Lysine; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Photochemotherapy	2018
Nonhistone targets of KAT2A and KAT2B implicated in cancer biology Biochemistry and cell biology = Biochimie et biologie cellulaire, 2019, Volume: 97, Issue:1 Topics: Acetylation; Animals; Histone Acetyltransferases; Humans; Lysine; Neoplasms; p300-CBP Transcription Factors; Protein Processing, Post-Translational	2019
[Progress in roles and mechanisms of deacetylase SIRT7]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2019, Jan-25, Volume: 35, Issue:1 Topics: Animals; Histones; Humans; Lysine; Neoplasms; Signal Transduction; Sirtuins	2019
Lysine methylation of transcription factors in cancer. Cell death & disease, 2019, 03-29, Volume: 10, Issue:4 Topics: Antineoplastic Agents; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational; Protein Stability; Transcription Factors	2019
Protein lysine acetylation guards metabolic homeostasis to fight against cancer. Oncogene, 2014, May-01, Volume: 33, Issue:18 Topics: Acetylation; Carcinogenesis; Genes, Neoplasm; Homeostasis; Humans; Lysine; Mitochondria; Neoplasms; Sirtuins	2014
Decoding the histone code: Role of H3K36me3 in mismatch repair and implications for cancer susceptibility and therapy. Cancer research, 2013, Nov-01, Volume: 73, Issue:21 Topics: Base Pair Mismatch; Histone Code; Humans; Lysine; Methylation; Neoplasms; Polycomb Repressive Complex 2	2013
The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle. Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:5 Topics: Animals; Cell Cycle; Cellular Reprogramming; Chromatin; DNA Damage; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms	2014
The bromodomain: from epigenome reader to druggable target. Biochimica et biophysica acta, 2014, Volume: 1839, Issue:8 Topics: Acetylation; Cardiovascular Diseases; Epigenesis, Genetic; Histones; HIV Infections; Humans; Lysine; Models, Molecular; Neoplasms; Protein Conformation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Structure, Tertiary; Small Molecule Libraries; Transcription Factors	2014
Examining the impact of gene variants on histone lysine methylation. Biochimica et biophysica acta, 2014, Volume: 1839, Issue:12 Topics: Animals; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasms; Polymorphism, Single Nucleotide	2014
Sumoylation of hypoxia inducible factor-1α and its significance in cancer. Science China. Life sciences, 2014, Volume: 57, Issue:7 Topics: Amino Acid Sequence; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ligases; Lysine; Molecular Sequence Data; Neoplasms; Polycomb-Group Proteins; Sumoylation; Ubiquitin-Protein Ligases	2014
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk. Rejuvenation research, 2015, Volume: 18, Issue:1 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disease Progression; Humans; Inflammation; Ligands; Lysine; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Oxidative Stress; Receptor for Advanced Glycation End Products; Risk Factors; Treatment Outcome	2015
Targeting histone lysine methylation in cancer. Pharmacology & therapeutics, 2015, Volume: 150 Topics: Animals; Antineoplastic Agents; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Molecular Targeted Therapy; Neoplasms; Signal Transduction	2015
KATs in cancer: functions and therapies. Oncogene, 2015, Sep-17, Volume: 34, Issue:38 Topics: Animals; Enzyme Inhibitors; Histone Acetyltransferases; Humans; Lysine; Neoplasms	2015
Epigenetic regulation by histone demethylases in hypoxia. Epigenomics, 2015, Volume: 7, Issue:5 Topics: Cardiovascular Diseases; Epigenesis, Genetic; Histones; Humans; Hypoxia; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Models, Genetic; Neoplasms	2015
The translation factor eIF5A and human cancer. Biochimica et biophysica acta, 2015, Volume: 1849, Issue:7 Topics: Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation; Humans; Lysine; Neoplasms; Oncogene Proteins; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Protein Isoforms; Protein Processing, Post-Translational; RNA-Binding Proteins	2015
JMJD3 as an epigenetic regulator in development and disease. The international journal of biochemistry & cell biology, 2015, Volume: 67 Topics: Animals; Chromatin; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Germ Layers; Histone Demethylases; Histones; Humans; Immunity, Innate; Jumonji Domain-Containing Histone Demethylases; Lysine; Mice; Neoplasms; Neurodegenerative Diseases; Nuclear Proteins; Polycomb Repressive Complex 2	2015
Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation. Food & function, 2016, Volume: 7, Issue:1 Topics: Biological Availability; Bone Diseases; Diet; Food; Food Contamination; Food Handling; Glycation End Products, Advanced; Hot Temperature; Humans; Lysine; Maillard Reaction; Neoplasms; Neurodegenerative Diseases; Oxidative Stress	2016
Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics. Pharmacology & therapeutics, 2016, Volume: 162 Topics: Acetylation; Animals; Antineoplastic Agents; Carcinogenesis; Humans; Lysine; Lysine Acetyltransferases; Neoplasms	2016
The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target. Oncotarget, 2016, 08-23, Volume: 7, Issue:34 Topics: Acetylation; Acetyltransferases; Animals; Biomarkers; Humans; Lysine; Lysine Acetyltransferases; Mice; Microtubule Proteins; Neoplasms; p300-CBP Transcription Factors; Prognosis; Protein Processing, Post-Translational	2016
Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer. Amino acids, 2016, Volume: 48, Issue:10 Topics: Animals; Biogenic Polyamines; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Mixed Function Oxygenases; Neoplasm Proteins; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins	2016
Writers and Erasers of Histone Lysine methylation with Clinically Applied Modulators: Promising Target for Cancer Therapy. Current pharmaceutical design, 2016, Volume: 22, Issue:39 Topics: Antineoplastic Agents; Histones; Humans; Lysine; Methylation; Neoplasms	2016
H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer. Advances in cancer research, 2016, Volume: 131 Topics: Animals; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Neoplasms; Transcription Factors	2016
Nonhistone Lysine Methylation in the Regulation of Cancer Pathways. Cold Spring Harbor perspectives in medicine, 2016, Nov-01, Volume: 6, Issue:11 Topics: Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; DNA Damage; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction	2016
Lysine acetylation and cancer: A proteomics perspective. Journal of proteomics, 2017, 01-06, Volume: 150 Topics: Acetylation; Humans; Lysine; Neoplasms; Nuclear Proteins; Protein Processing, Post-Translational; Proteomics	2017
The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins. International journal of molecular sciences, 2016, Nov-07, Volume: 17, Issue:11 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Chromatin; Epigenesis, Genetic; Evolution, Molecular; Gene Duplication; Histones; Humans; Lysine; Multigene Family; Neoplasms; Protein Domains; Protein Isoforms; Protein Serine-Threonine Kinases; Signal Transduction; Transcription Factors; Virus Diseases	2016
Bromodomain inhibitors and cancer therapy: From structures to applications. Epigenetics, 2017, 05-04, Volume: 12, Issue:5 Topics: Acetylation; Antineoplastic Agents; Chromatin; Epigenesis, Genetic; Histone Acetyltransferases; Histone Chaperones; Histone Code; Humans; Lysine; Neoplasms; Nuclear Proteins; Protein Domains	2017
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer. Nature reviews. Molecular cell biology, 2017, Volume: 18, Issue:4 Topics: Acylation; Animals; Chromatin Assembly and Disassembly; Gene Expression Regulation; Histones; Homeostasis; Humans; Lysine; Mutation; Neoplasms; Oncogene Proteins, Fusion; Protein Domains; Protein Processing, Post-Translational; Proteins; Tumor Suppressor Proteins	2017
The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways. The Journal of biological chemistry, 2017, 03-03, Volume: 292, Issue:9 Topics: Animals; Carcinogenesis; Catalysis; Fanconi Anemia; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Lysine; Neoplasms; NF-kappa B; Oncogenes; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Ubiquitin; Ubiquitination	2017
Dynamic protein methylation in chromatin biology. Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:3 Topics: Animals; Arginine; Chromatin; DNA Damage; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation; Germ Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Models, Molecular; Molecular Structure; Neoplasms; Oxidoreductases, N-Demethylating; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; Tumor Suppressor Protein p53	2009
Biomarkers for predicting clinical responses to HDAC inhibitors. Cancer letters, 2009, Aug-08, Volume: 280, Issue:2 Topics: Acetylation; Antineoplastic Agents; Biomarkers, Tumor; Clinical Trials as Topic; Gene Expression Profiling; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Neoplasms; Predictive Value of Tests	2009
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors. ChemMedChem, 2009, Volume: 4, Issue:10 Topics: Arginine; Enzyme Inhibitors; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational	2009
Lysine 63 polyubiquitination in immunotherapy and in cancer-promoting inflammation. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22 Topics: Animals; Humans; Immunotherapy; Inflammation; Lysine; Models, Biological; Neoplasms; NF-kappa B; Polyubiquitin; Protein Processing, Post-Translational; Signal Transduction; Ubiquitin; Ubiquitination	2009
Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene, 2010, Aug-12, Volume: 29, Issue:32 Topics: Animals; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Lysine; Neoplasms; Phosphoric Monoester Hydrolases; Protein Kinases; Ubiquitination	2010
Errors in erasure: links between histone lysine methylation removal and disease. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 2011, Volume: 67 Topics: Animals; Cathepsin L; Cell Cycle Proteins; Histone Chaperones; Histone Demethylases; Histones; Humans; Lysine; Methylation; Neoplasms; Transcription Factors	2011
Deacetylation of nonhistone proteins by HDACs and the implications in cancer. Handbook of experimental pharmacology, 2011, Volume: 206 Topics: Acetylation; Animals; Apoptosis; Autophagy; Cell Differentiation; DNA Damage; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Humans; Lysine; Neoplasm Invasiveness; Neoplasms; Protein Processing, Post-Translational	2011
Alterations in histone H4 lysine 20 methylation: implications for cancer detection and prevention. Antioxidants & redox signaling, 2012, Jul-15, Volume: 17, Issue:2 Topics: Animals; Epigenesis, Genetic; Epigenomics; Histones; Humans; Lysine; Methylation; Neoplasms	2012
Targeting histone deacetylases: development of vorinostat for the treatment of cancer. Epigenomics, 2010, Volume: 2, Issue:3 Topics: Acetylation; Animals; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Neoplasms; Vorinostat	2010
eIF5A isoforms and cancer: two brothers for two functions? Amino acids, 2013, Volume: 44, Issue:1 Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Humans; Lysine; Neoplasms; Peptide Initiation Factors; Protein Isoforms; RNA-Binding Proteins	2013
Modulation of cell cycle regulators by HDACs. Frontiers in bioscience (Scholar edition), 2012, 01-01, Volume: 4, Issue:3 Topics: Cell Cycle; Cell Cycle Proteins; Cell Growth Processes; Histone Deacetylases; Histones; Humans; Lysine; Neoplasms	2012
Oncoepigenomics: making histone lysine methylation count. European journal of medicinal chemistry, 2012, Volume: 56 Topics: Animals; Epigenomics; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasms	2012
Tipping the lysine methylation balance in disease. Biopolymers, 2013, Volume: 99, Issue:2 Topics: Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Mutation; Neoplasms; Nervous System Diseases	2013
Proteasome inhibition: a new anti-inflammatory strategy. Journal of molecular medicine (Berlin, Germany), 2003, Volume: 81, Issue:4 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Asthma; Boronic Acids; Bortezomib; Clinical Trials as Topic; Cysteine Endopeptidases; Disease Models, Animal; Humans; Inflammation; Lysine; Models, Biological; Models, Chemical; Multienzyme Complexes; Multiple Sclerosis; Neoplasms; NF-kappa B; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Psoriasis; Pyrazines; Reperfusion Injury	2003
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic acids research, 2004, Volume: 32, Issue:3 Topics: Acetylation; Acetyltransferases; Humans; Leukemia; Lysine; Neoplasms; Protein Structure, Tertiary; Proteins; Substrate Specificity	2004
SUMO: a ubiquitin-like protein modifier. The Yale journal of biology and medicine, 2005, Volume: 78, Issue:4 Topics: Animals; Cell Cycle; Chromosomes; DNA Damage; Humans; Inflammation; Lysine; Neoplasms; Protein Binding; Saccharomyces cerevisiae; SUMO-1 Protein; Ubiquitin	2005
Pharmacological targeting of lysine acetyltransferases in human disease: a progress report. Drug discovery today, 2007, Volume: 12, Issue:1-2 Topics: Acetyltransferases; Curcumin; Drug Delivery Systems; Drug Design; Enzyme Inhibitors; Humans; Lysine; Models, Molecular; Molecular Structure; Neoplasms	2007
Histidine-lysine peptides as carriers of nucleic acids. Drug news & perspectives, 2007, Volume: 20, Issue:2 Topics: Angiostatic Proteins; Animals; DNA; Gene Expression Regulation, Neoplastic; Genetic Therapy; Histidine; Humans; Lysine; Neoplasms; Neovascularization, Pathologic; Nucleic Acid Conformation; Peptides; Protein Conformation; RNA Interference; RNA, Small Interfering; Transfection; Tumor Burden	2007
The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection. Cell cycle (Georgetown, Tex.), 2007, Jun-01, Volume: 6, Issue:11 Topics: Animals; Caenorhabditis elegans Proteins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Epigenesis, Genetic; Gene Expression Regulation; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Lysine; Mammals; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; Nucleosomes; Oxidoreductases, N-Demethylating; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Repressor Proteins; Retinoblastoma-Binding Protein 2; Saccharomyces cerevisiae Proteins; Substrate Specificity; Tumor Suppressor Proteins	2007
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene, 2007, Aug-13, Volume: 26, Issue:37 Topics: Acetylation; Aging; Diabetes Mellitus; Histone Deacetylases; Histones; Humans; Lysine; NAD; Neoplasms; Sirtuins	2007
Histone lysine demethylases: emerging roles in development, physiology and disease. Nature reviews. Genetics, 2007, Volume: 8, Issue:11 Topics: Amino Acid Sequence; Animals; Gene Expression Regulation, Developmental; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Molecular Sequence Data; Neoplasms; Nervous System Diseases	2007
[Research progress on the relationship between nutrition and cancer epigenetics---histone modification mechanisms]. Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:9 Topics: Acetylation; Biotinylation; DNA, Neoplasm; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Neoplasms; Nutritional Physiological Phenomena; Phosphorylation; Poly Adenosine Diphosphate Ribose	2007
[Biological diversity of protein lysine acetylation which has been revealed by small molecule inhibitors]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2007, Volume: 52, Issue:13 Suppl Topics: Acetylation; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Cortactin; Enzyme Inhibitors; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Lysine; mRNA Cleavage and Polyadenylation Factors; Neoplasms; Tubulin; Tumor Suppressor Protein p53	2007
Polyamines. Annual review of biochemistry, 1984, Volume: 53 Topics: Adenosylmethionine Decarboxylase; Animals; Arginase; Aspergillus nidulans; Carboxy-Lyases; Cloning, Molecular; DNA; Escherichia coli; Lysine; Mutation; Neoplasms; Neurospora crassa; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Physarum; Plants; Polyamines; Protein Biosynthesis; Protein Kinases; Protein Processing, Post-Translational; Putrescine; RNA; Saccharomyces cerevisiae; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase	1984
No grip, no growth: the conceptual basis of excessive proteolysis in the treatment of cancer. European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:13 Spec No Topics: Angiogenesis Inhibitors; Angiostatins; Antineoplastic Agents; Carboxypeptidase B2; Carboxypeptidases; Collagen; Endostatins; Humans; Lysine; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Peptide Fragments; Plasminogen; Plasminogen Activators; Thrombolytic Therapy; Urokinase-Type Plasminogen Activator	2000
Histone methylation versus histone acetylation: new insights into epigenetic regulation. Current opinion in cell biology, 2001, Volume: 13, Issue:3 Topics: Acetylation; Animals; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; DNA Methylation; Gene Expression Regulation, Developmental; Gene Silencing; Heterochromatin; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms; Protein Methyltransferases; Transcription, Genetic	2001
Acetyllysine-binding and function of bromodomain-containing proteins in chromatin. Frontiers in bioscience : a journal and virtual library, 2001, Aug-01, Volume: 6 Topics: Acetyltransferases; Amino Acid Motifs; Animals; Binding Sites; Chromatin; Histone Acetyltransferases; Histones; Humans; Lysine; Mutation; Neoplasms; Nuclear Proteins; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Terminology as Topic; Transcription, Genetic	2001
The bromodomain: a chromatin browser? Frontiers in bioscience : a journal and virtual library, 2001, Aug-01, Volume: 6 Topics: Acetyltransferases; Amino Acid Sequence; Animals; Chromatin; Histone Acetyltransferases; Humans; Lysine; Molecular Sequence Data; Mutation; Neoplasms; Nuclear Proteins; Oncogene Proteins, Fusion; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Transcription, Genetic	2001

Trials

1 trial(s) available for lysine and Benign Neoplasms

Article	Year
[First results of the clinical use of injectable lysine acetylsalicylate]. Minerva medica, 1972, Nov-21, Volume: 63, Issue:83 Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Female; Glycine; Headache; Humans; Injections, Intramuscular; Injections, Intravenous; Joint Diseases; Lysine; Male; Middle Aged; Neoplasms; Neuritis; Osteoarthritis; Pain	1972

Article

Year

[First results of the clinical use of injectable lysine acetylsalicylate].

Minerva medica, 1972, Nov-21, Volume: 63, Issue:83

Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Female; Glycine; Headache; Humans; Injections, Intramuscular; Injections, Intravenous; Joint Diseases; Lysine; Male; Middle Aged; Neoplasms; Neuritis; Osteoarthritis; Pain

1972

Other Studies

225 other study(ies) available for lysine and Benign Neoplasms

Article	Year
Hypoxia-activated KDAC inhibitor: Taking a breath from untargeted therapy. Cell chemical biology, 2021, 09-16, Volume: 28, Issue:9 Topics: Animals; Histone Deacetylases; Hypoxia; Lysine; Neoplasms; Prodrugs	2021
"Clickable" Albumin Binders for Modulating the Tumor Uptake of Targeted Radiopharmaceuticals. Journal of medicinal chemistry, 2022, 01-13, Volume: 65, Issue:1 Topics: Albumins; Animals; Copper Radioisotopes; Lysine; Mice; Neoplasms; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Structure-Activity Relationship; Tissue Distribution; Xenograft Model Antitumor Assays	2022
Histone demethylase JMJD1A in cancer progression and therapeutic resistance. Molecular carcinogenesis, 2022, Volume: 61, Issue:4 Topics: Drug Resistance, Neoplasm; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Neoplasms; Transcription Factors	2022
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours. Acta pharmacologica Sinica, 2022, Volume: 43, Issue:9 Topics: Adaptor Proteins, Signal Transducing; Humans; Lipid Metabolism; Lysine; Neoplasms; Protein-Arginine N-Methyltransferases; Sirtuins; Sterol Regulatory Element Binding Protein 1; Ubiquitin-Protein Ligases	2022
Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Acetylation; Acetyltransferases; Enzyme Inhibitors; Histone Acetyltransferases; Histones; Humans; Lysine; Neoplasms; Pyrazines; Structure-Activity Relationship	2022
Structural and dynamic determinants for highly selective RET kinase inhibition reveal cryptic druggability. Journal of advanced research, 2023, Volume: 45 Topics: Humans; Lysine; Molecular Conformation; Molecular Dynamics Simulation; Neoplasms; Proto-Oncogene Proteins c-ret	2023
Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A. Biomolecules, 2022, 04-27, Volume: 12, Issue:5 Topics: Demethylation; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms; Protein Processing, Post-Translational	2022
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy. Bosnian journal of basic medical sciences, 2022, Oct-23, Volume: 22, Issue:6 Topics: Antineoplastic Agents; Arginine; Camptothecin; Cell Line, Tumor; Humans; Lactones; Lysine; Mitochondria; Neoplasms; Prodrugs; Reactive Oxygen Species; Water	2022
Impact of Radiolabeling Strategies on the Pharmacokinetics and Distribution of an Anti-PD-L1 PET Ligand. Molecular pharmaceutics, 2022, 10-03, Volume: 19, Issue:10 Topics: Amides; Animals; B7-H1 Antigen; Cell Line, Tumor; Fluorine Radioisotopes; Immunoglobulin Fragments; Ligands; Ligases; Lysine; Mice; Neoplasms; Peptides; Positron-Emission Tomography; Radiopharmaceuticals; Thioctic Acid; Tissue Distribution	2022
Rational Design of T-Cell- and B-Cell-Based Therapeutic Cancer Vaccines. Accounts of chemical research, 2022, 09-20, Volume: 55, Issue:18 Topics: Adjuvants, Immunologic; Cancer Vaccines; CD8-Positive T-Lymphocytes; DNA; Epitopes; Humans; Hydrogels; Immunoglobulin G; Interferons; Lysine; Neoplasms; Phosphorus; Receptors, Pattern Recognition	2022
The histone methyltransferase SETD2 negatively regulates cell size. Journal of cell science, 2022, 10-01, Volume: 135, Issue:19 Topics: Cell Size; Histone Methyltransferases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms; RNA Polymerase II; Tumor Suppressor Proteins	2022
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase. Angewandte Chemie (International ed. in English), 2022, 11-21, Volume: 61, Issue:47 Topics: Animals; HEK293 Cells; Humans; Lysine; Mice; Neoplasms; Sirtuins	2022
Type I interferon induces cancer stem cells-mediated chemotherapy resistance. Oncoimmunology, 2022, Volume: 11, Issue:1 Topics: Interferon Type I; Lysine; Neoplasms; Neoplastic Stem Cells	2022
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization. Science advances, 2022, 11-11, Volume: 8, Issue:45 Topics: Acidosis; Animals; Cell Line, Tumor; Glutamic Acid; Gold; Hypoxia; Lysine; Mice; Nanotubes; Neoplasms; Tumor Microenvironment	2022
Combination of Se-methylselenocysteine, D-α-tocopheryl succinate, β-carotene, and L-lysine can prevent cancer metastases using as an adjuvant therapy. Journal of Zhejiang University. Science. B, 2022, Nov-15, Volume: 23, Issue:11 Topics: alpha-Tocopherol; Animals; Antioxidants; Apoptosis; beta Carotene; Cell Line, Tumor; Cell Proliferation; Lysine; Mice; Neoplasms; Paclitaxel; Quality of Life; Succinates	2022
Lasso peptide microcin J25 variant containing RGD motif as a PET probe for integrin a v ß 3 in tumor imaging. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Jan-01, Volume: 180 Topics: Animals; Escherichia coli; Integrin alphaVbeta3; Lysine; Mice; Molecular Probes; Neoplasms; Positron-Emission Tomography; Tissue Distribution	2023
Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors. European journal of medicinal chemistry, 2023, Feb-05, Volume: 247 Topics: Humans; Lysine; NAD; Neoplasms; Pyrazolones; Sirtuins	2023
Histone tail electrostatics modulate E2-E3 enzyme dynamics: a gateway to regulate ubiquitination machinery. Physical chemistry chemical physics : PCCP, 2023, Jan-27, Volume: 25, Issue:4 Topics: Histones; Humans; Lysine; Neoplasms; Nucleosomes; Static Electricity; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination	2023
New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape. Biology open, 2023, 03-15, Volume: 12, Issue:3 Topics: Animals; Gene Expression; Humans; Lysine; Mice; Neoplasms	2023
Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner. Cell research, 2023, Volume: 33, Issue:5 Topics: Acetyltransferases; Acylation; Epigenesis, Genetic; Humans; Lysine; N-Terminal Acetyltransferases; Neoplasms; Protein Processing, Post-Translational; Ubiquitin-Specific Proteases	2023
Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability. International journal of molecular sciences, 2023, Mar-23, Volume: 24, Issue:7 Topics: Amino Acids; Eukaryotic Initiation Factors; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Neoplasms; Peptide Initiation Factors; Protein Stability	2023
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation. The Journal of biological chemistry, 2023, Volume: 299, Issue:6 Topics: Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasms	2023
Lysine catabolism reprograms tumour immunity through histone crotonylation. Nature, 2023, Volume: 617, Issue:7962 Topics: Animals; Chromatin; Glutaryl-CoA Dehydrogenase; Histones; Humans; Interferon Type I; Lysine; Mice; Neoplasms; Protein Processing, Post-Translational; RNA, Double-Stranded	2023
RAFT Polymer-Antibody Conjugation: Squaramide Ester Chemistry Leads to Conjugates with a Therapeutic Anti-EGFR Antibody with Full Retention of Activity and Increased Tumor Uptake Molecular pharmaceutics, 2023, 06-05, Volume: 20, Issue:6 Topics: Animals; Antibodies; Humans; Lysine; Mice; Neoplasms; Polymers; Proteins; Reproducibility of Results	2023
Lysine metabolism at the nexus of crotonylation and tumor immunity. Cell research, 2023, Volume: 33, Issue:11 Topics: Histones; Humans; Lysine; Neoplasms; Protein Processing, Post-Translational	2023
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Science advances, 2023, 08-09, Volume: 9, Issue:32 Topics: Drosophila Proteins; Histones; Humans; Lysine; Neoplasms; Nucleosomes; Polycomb-Group Proteins; Repressor Proteins; Tumor Suppressor Proteins; Ubiquitin Thiolesterase	2023
CBX4 promotes antitumor immunity by suppressing Pdcd1 expression in T cells. Molecular oncology, 2023, Volume: 17, Issue:12 Topics: Animals; Ligases; Lysine; Mice; Mice, Knockout; Neoplasms; Polycomb Repressive Complex 1; Polycomb-Group Proteins; Programmed Cell Death 1 Receptor; T-Lymphocytes	2023
NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism-mediated cancer radiotherapy. Cell reports, 2023, 10-31, Volume: 42, Issue:10 Topics: Carcinogenesis; Fatty Acids; Histone-Lysine N-Methyltransferase; Humans; Lysine; Neoplasms; Repressor Proteins; Sirtuin 1	2023
Epigenetic profiles of elevated cell free circulating H3.1 nucleosomes as potential biomarkers for non-Hodgkin lymphoma. Scientific reports, 2023, Sep-28, Volume: 13, Issue:1 Topics: Acetylation; Biomarkers; Epigenesis, Genetic; Histones; Humans; Lymphoma, Non-Hodgkin; Lysine; Neoplasms; Nucleosomes; Protein Processing, Post-Translational	2023
Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. American journal of human genetics, 2023, 11-02, Volume: 110, Issue:11 Topics: Congenital Abnormalities; Developmental Disabilities; Drosophila; Drosophila Proteins; Gain of Function Mutation; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms	2023
Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer. BMC medical genomics, 2023, 11-10, Volume: 16, Issue:1 Topics: Breast Neoplasms; Female; Histones; Humans; Immunotherapy; Lactic Acid; Lysine; Neoplasms; Prognosis; Tumor Microenvironment	2023
RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Molecular cell, 2019, 10-03, Volume: 76, Issue:1 Topics: Autophagy; Autophagy-Related Protein 7; Autophagy-Related Protein-1 Homolog; Cell Proliferation; DNA Polymerase III; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Homologous Recombination; Humans; Intracellular Signaling Peptides and Proteins; Ligases; Lysine; Neoplasms; Nucleotidyltransferases; Protein Stability; Rad52 DNA Repair and Recombination Protein; RNA-Binding Proteins; Signal Transduction; Sumoylation; Telomere; Telomere Homeostasis	2019
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer. BMC medical genetics, 2019, 10-21, Volume: 20, Issue:1 Topics: Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Matrix Metalloproteinase 8; Neoplasms; Polymorphism, Single Nucleotide; Threonine	2019
Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer. Biochimica et biophysica acta. Molecular cell research, 2020, Volume: 1867, Issue:1 Topics: Alanine; Amino Acid Substitution; Apoptosomes; Apoptotic Protease-Activating Factor 1; Case-Control Studies; Cell Transformation, Neoplastic; Cells, Cultured; Cytochromes c; Female; Humans; Lysine; Male; Models, Molecular; Molecular Docking Simulation; Mutant Proteins; Neoplasms; Nucleotides; PC-3 Cells; Protein Binding; Protein Interaction Mapping; Protein Multimerization; Signal Transduction	2020
Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation. Bioconjugate chemistry, 2020, 01-15, Volume: 31, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Benzodiazepines; Cell Line, Tumor; Female; Humans; Immunoconjugates; Lysine; Mice; Mice, SCID; Neoplasms; Oxindoles; Therapeutic Index	2020
Histone Lysine Methylation Dynamics Control Cancer discovery, 2020, Volume: 10, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cell Line, Tumor; DNA Copy Number Variations; DNA Methylation; Epigenesis, Genetic; ErbB Receptors; Gene Amplification; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms; Protein Kinase Inhibitors	2020
Aspirin Reshapes Acetylomes in Inflammatory and Cancer Cells via CoA-Dependent and CoA-Independent Pathways. Journal of proteome research, 2020, 02-07, Volume: 19, Issue:2 Topics: Acetyl Coenzyme A; Acetylation; Aspirin; Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Proteome	2020
A novel EZH2 inhibitor induces synthetic lethality and apoptosis in PBRM1-deficient cancer cells. Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:7 Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Indoles; Lysine; Methylation; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Prognosis; Pyridones; Reproducibility of Results; Synthetic Lethal Mutations; Transcription Factors	2020
Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-17, Volume: 117, Issue:11 Topics: Albuminuria; Animals; Antibodies, Monoclonal; Capillary Leak Syndrome; Disease Models, Animal; Female; Fluorescent Dyes; Half-Life; Humans; Immunotoxins; Intravital Microscopy; Kidney Glomerulus; Kidney Tubules, Proximal; Lysine; Mesothelin; Mice; Microscopy, Fluorescence; Neoplasms; Recombinant Proteins; Renal Elimination; Serum Albumin; Staining and Labeling	2020
SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells. Molecular oncology, 2020, Volume: 14, Issue:9 Topics: Animals; Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Nude; MicroRNAs; Mutation; Neoplasms; Protein Binding; RNA-Binding Proteins; Signal Transduction; Stress, Physiological; Sumoylation; Uridine	2020
Host-Guest Protein Assembly for Affinity Purification of Methyllysine Proteomes. Analytical chemistry, 2020, 07-07, Volume: 92, Issue:13 Topics: Amantadine; Bridged-Ring Compounds; Chromatography, Affinity; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; HeLa Cells; Humans; Imidazoles; Lysine; Methylation; Neoplasms; Peptides	2020
HybridSucc: A Hybrid-learning Architecture for General and Species-specific Succinylation Site Prediction. Genomics, proteomics & bioinformatics, 2020, Volume: 18, Issue:2 Topics: Acylation; Algorithms; Amino Acid Sequence; Area Under Curve; Humans; Lysine; Machine Learning; Neoplasms; Proteins; Proteome; ROC Curve; Species Specificity; Succinic Acid	2020
On-chip protein separation with single-molecule resolution. Scientific reports, 2020, 09-17, Volume: 10, Issue:1 Topics: Acrylic Resins; Calibration; Cell Line, Tumor; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Molecular Weight; Neoplasms; Protein Array Analysis; Proteins; Proteomics; Sodium Dodecyl Sulfate	2020
Deep learning based prediction of reversible HAT/HDAC-specific lysine acetylation. Briefings in bioinformatics, 2020, 09-25, Volume: 21, Issue:5 Topics: Acetylation; Datasets as Topic; Deep Learning; Histone Deacetylases; Humans; Internet; Lysine; Neoplasms	2020
Lysine acetylation of NKG2D ligand Rae-1 stabilizes the protein and sensitizes tumor cells to NKG2D immune surveillance. Cancer letters, 2021, 04-01, Volume: 502 Topics: Acetylation; Cell Line, Tumor; GPI-Linked Proteins; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mutation; Neoplasm Transplantation; Neoplasms; NK Cell Lectin-Like Receptor Subfamily K; Nuclear Matrix-Associated Proteins; Nucleocytoplasmic Transport Proteins; p300-CBP Transcription Factors; Protein Stability; Survival Analysis; Tissue Array Analysis; Tumor Escape	2021
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin. Nucleic acids research, 2021, 01-11, Volume: 49, Issue:1 Topics: Acetylation; Animals; Cell Line, Tumor; Cell Nucleus; Chromatin; Datasets as Topic; DNA Glycosylases; DNA Repair; Evolution, Molecular; Genes, Helminth; Genes, Homeobox; HEK293 Cells; Helminth Proteins; Humans; Invertebrates; Lysine; Mutation; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Protein Processing, Post-Translational; Proteome; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Initiation Site; Vertebrates	2021
mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression. Genes & development, 2021, 01-01, Volume: 35, Issue:1-2 Topics: Acetylation; Animals; Carcinogenesis; Cell Cycle Checkpoints; Embryo, Mammalian; Lysine; Mice; Mutation; Neoplasms; Proto-Oncogene Proteins c-mdm2; Sirolimus; Survival Analysis; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2021
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 01-21, Volume: 184, Issue:2 Topics: Adult; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Breaks, Double-Stranded; DNA Replication; Drug Resistance, Neoplasm; F-Box Proteins; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Immune Checkpoint Inhibitors; Immunity; Interferons; Lysine; Male; Methylation; Middle Aged; Neoplasm Proteins; Neoplasms; Nucleosomes; Repetitive Sequences, Nucleic Acid; Signal Transduction; Transcription, Genetic; Treatment Outcome	2021
Lysine analogue use during cancer surgery: a survey from a Canadian tertiary care centre. Current oncology (Toronto, Ont.), 2020, Volume: 27, Issue:6 Topics: Aminocaproic Acid; Blood Loss, Surgical; Humans; Lysine; Neoplasms; Ontario; Surveys and Questionnaires; Tertiary Care Centers; Tranexamic Acid	2020
SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs. Nucleic acids research, 2021, 03-18, Volume: 49, Issue:5 Topics: Adenosine; Animals; Cell Hypoxia; Cell Line; Disease Progression; Humans; Lysine; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oxidative Stress; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Sumoylation; Transcriptome; Ubiquitination	2021
Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation. Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-02, Volume: 118, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Carcinogenesis; Cell Line; Chromatin; CRISPR-Cas Systems; Cytarabine; Decitabine; Epigenesis, Genetic; Gene Editing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methylation; Mice; Mutation; Neoplasm Proteins; Neoplasms; Phenotype; Protein Isoforms; Protein Processing, Post-Translational; Repressor Proteins; Transcriptome	2021
Development of an Journal of medicinal chemistry, 2021, 03-25, Volume: 64, Issue:6 Topics: Animals; Cell Line, Tumor; Fluorine Radioisotopes; GTP-Binding Proteins; Humans; Lysine; Mice; Neoplasms; Piperazines; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases	2021
Detection of Tumor DNA in Human Plasma with a Functional PLL-Based Surface Layer and Plasmonic Biosensing. ACS sensors, 2021, 06-25, Volume: 6, Issue:6 Topics: DNA; Humans; Lysine; Neoplasms; Peptide Nucleic Acids; Surface Plasmon Resonance	2021
Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders. Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Jun-22, Volume: 23, Issue:35 Topics: Amino Acids; Base Sequence; Circular Dichroism; DNA; G-Quadruplexes; Humans; Imides; Ligands; Lysine; Naphthalenes; Neoplasms; Promoter Regions, Genetic; Solubility; Telomere; Thermodynamics; Up-Regulation; Water	2017
Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness. Oncogene, 2017, 12-07, Volume: 36, Issue:49 Topics: Acetylation; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Female; HEK293 Cells; HeLa Cells; Heme Oxygenase-1; Humans; Lysine; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Neoplasms; Transplantation, Heterologous; Tumor Burden	2017
Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment. Biochemistry, 2018, 05-01, Volume: 57, Issue:17 Topics: Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Lysine; Magnetic Resonance Spectroscopy; Multiprotein Complexes; Mutation; Neoplasms; Promoter Regions, Genetic; Protein Binding; Protein Domains; RNA Polymerase II; TATA-Binding Protein Associated Factors; Transcription, Genetic; Translocation, Genetic	2018
Src SUMOylation Inhibits Tumor Growth Via Decreasing FAK Y925 Phosphorylation. Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:12 Topics: Animals; Cell Line; Disease Progression; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysine; Mice; Models, Molecular; Mutation; Neoplasms; Phosphorylation; Protein Conformation; src-Family Kinases; Sumoylation	2017
Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor. Nutrients, 2017, Oct-27, Volume: 9, Issue:11 Topics: Acetylation; Antineoplastic Agents, Phytogenic; Cell Cycle Proteins; Diet; Epigenesis, Genetic; Gene Expression; Histones; Humans; Kinetics; Lysine; Molecular Docking Simulation; Neoplasms; Nuclear Proteins; Phytotherapy; Plant Extracts; Proteins; Resveratrol; Stilbenes; Transcription Factors	2017
Physalis Mottle Virus-Like Particles as Nanocarriers for Imaging Reagents and Drugs. Biomacromolecules, 2017, Dec-11, Volume: 18, Issue:12 Topics: Animals; Cell Line; Cell Line, Tumor; Doxorubicin; Drug Carriers; HeLa Cells; Humans; Indicators and Reagents; Lysine; Maleimides; Mice; Mitoxantrone; Nanoparticles; Neoplasms; Pharmaceutical Preparations; Photosensitizing Agents; RAW 264.7 Cells; Tymovirus	2017
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase. Nature, 2017, 12-14, Volume: 552, Issue:7684 Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Crystallography, X-Ray; Female; Gene Expression Regulation; Histone Acetyltransferases; Histones; Humans; Ketoglutarate Dehydrogenase Complex; Lysine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Neoplasms; Protein Binding; Protein Domains; Transcription Initiation Site; Tyrosine	2017
Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells. PloS one, 2017, Volume: 12, Issue:12 Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Epigenesis, Genetic; HEK293 Cells; Humans; Lysine; Mice; Mice, Nude; Neoplasms; Oxidative Stress; Real-Time Polymerase Chain Reaction; Signal Transduction	2017
Synthesis, DNA Binding, and Anticancer Properties of Bis-Naphthalimide Derivatives with Lysine-Modified Polyamine Linkers. Molecules (Basel, Switzerland), 2018, Jan-29, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Cell Line, Tumor; DNA, Neoplasm; Humans; Lysine; Naphthalimides; Neoplasms; Polyamines	2018
Vesicles mimicking normal and cancer cell membranes exhibit differential responses to the cell-penetrating peptide Pep-1. Biochimica et biophysica acta. Biomembranes, 2018, Volume: 1860, Issue:6 Topics: Amino Acid Sequence; Calorimetry, Differential Scanning; Cell Membrane; Cell-Penetrating Peptides; Cysteamine; Dose-Response Relationship, Drug; Liposomes; Lysine; Membrane Lipids; Microscopy, Electron, Scanning; Neoplasms; Peptides; Phosphates; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Static Electricity; Thermogravimetry	2018
Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing. Genome medicine, 2018, 04-17, Volume: 10, Issue:1 Topics: Alternative Splicing; Cell Line, Tumor; Cluster Analysis; Exons; Gene Expression Regulation, Neoplastic; Gene Ontology; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms; Nucleotide Motifs; Reproducibility of Results; RNA Splice Sites	2018
Identification of a peptide inhibitor for the histone methyltransferase WHSC1. PloS one, 2018, Volume: 13, Issue:5 Topics: Crystallography, X-Ray; Enzyme Inhibitors; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Neoplasms; Norleucine; Peptides; PR-SET Domains; Protein Conformation; Repressor Proteins	2018
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width. Nature communications, 2018, 05-16, Volume: 9, Issue:1 Topics: Animals; Gene Expression Profiling; Genomics; HCT116 Cells; Histone Code; Histones; Humans; Liver; Lysine; Male; Methionine; Methylation; Mice, Inbred C57BL; Neoplasms	2018
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair. Science signaling, 2018, 06-05, Volume: 11, Issue:533 Topics: DNA; DNA Damage; DNA Repair; Humans; Lysine; Models, Molecular; Neoplasms; Polyubiquitin; Protein Processing, Post-Translational; Signal Transduction; Tumor Cells, Cultured; Ubiquitination	2018
MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites. Scientific reports, 2018, Jul-18, Volume: 8, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Chromatin; DNA Damage; DNA Methylation; DNA Repair; Genomic Instability; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Neoplasms; Nuclear Proteins; Trans-Activators; Tumor Cells, Cultured	2018
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2. Science signaling, 2018, 11-13, Volume: 11, Issue:556 Topics: Circadian Rhythm; DNA, Complementary; HCT116 Cells; Humans; Lysine; Neoplasms; Period Circadian Proteins; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination	2018
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells. Nature, 2018, Volume: 564, Issue:7734 Topics: Animals; F-Box Proteins; Female; HEK293 Cells; Humans; Interleukin-2; Lysine; Male; Melanoma, Experimental; Mice; Neoplasms; Programmed Cell Death 1 Receptor; Proteasome Endopeptidase Complex; T-Lymphocytes; Tumor Microenvironment; Ubiquitination	2018
Identification of selective and reversible LSD1 inhibitors with anti-metastasis activity by high-throughput docking. Bioorganic & medicinal chemistry letters, 2019, 02-15, Volume: 29, Issue:4 Topics: Cell Line, Tumor; Demethylation; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Lysine; Methylation; Molecular Docking Simulation; Neoplasm Metastasis; Neoplasms; Structure-Activity Relationship	2019
Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells Cancer research, 2019, 04-15, Volume: 79, Issue:8 Topics: Animals; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Female; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neoplastic Stem Cells; Peptide Fragments; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2019
The expanding landscape of 'oncohistone' mutations in human cancers. Nature, 2019, Volume: 567, Issue:7749 Topics: Cell Transformation, Neoplastic; Histones; Humans; Lysine; Methylation; Mutation; Neoplasms; Nucleosomes; Protein Domains; Protein Processing, Post-Translational	2019
A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging. Nanomedicine : nanotechnology, biology, and medicine, 2019, Volume: 19 Topics: Animals; Cell Death; Cell Line, Tumor; Cell Survival; Endocytosis; Humans; Ligands; Light; Lysine; Mice; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Oligopeptides; Porosity; Silicon Dioxide; Tissue Distribution; Toxicity Tests, Acute	2019
Fine-tuning AKT kinase activity through direct lysine methylation. Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:9 Topics: Animals; Carcinogenesis; Histone-Lysine N-Methyltransferase; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt	2019
SUMOylation of Csk Negatively Modulates its Tumor Suppressor Function. Neoplasia (New York, N.Y.), 2019, Volume: 21, Issue:7 Topics: CSK Tyrosine-Protein Kinase; Humans; Hydrogen Peroxide; Lysine; Molecular Chaperones; Neoplasms; Phosphorylation; Protein Binding; Protein Inhibitors of Activated STAT; Protein Processing, Post-Translational; Small Ubiquitin-Related Modifier Proteins; src-Family Kinases; SUMO-1 Protein; Sumoylation; Ubiquitin-Protein Ligases	2019
Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys. Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9 Topics: A549 Cells; Animals; Doxycycline; Fluorescein-5-isothiocyanate; Folate Receptor 1; Folic Acid; HeLa Cells; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Molecular Targeted Therapy; Neoplasms; Oligopeptides; Polycystic Kidney Diseases; Protein Kinase C; Tissue Distribution; Trityl Compounds; Xenograft Model Antitumor Assays	2019
MYC activity is negatively regulated by a C-terminal lysine cluster. Oncogene, 2014, Feb-20, Volume: 33, Issue:8 Topics: Animals; Cell Division; Gene Expression Regulation; Genes, myc; Heterografts; Humans; Lysine; Neoplasms; Phosphorylation; Protein Stability; Rats	2014
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression. The Journal of biological chemistry, 2013, Jun-28, Volume: 288, Issue:26 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; COS Cells; Cysteine Endopeptidases; Endopeptidases; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasms; Protein Processing, Post-Translational; Repressor Proteins; RNA Polymerase III; Small Ubiquitin-Related Modifier Proteins; Transcription Factors; Transcription, Genetic	2013
Enzymatic properties and anticancer activity of L-lysine α-oxidase from Trichoderma cf. aureoviride Rifai BKMF-4268D. Anti-cancer drugs, 2013, Volume: 24, Issue:8 Topics: Amino Acid Oxidoreductases; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Stability; Female; Fungal Proteins; HT29 Cells; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; K562 Cells; Kinetics; Lysine; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Weight; Neoplasms; Protein Multimerization; Substrate Specificity; Time Factors; Trichoderma; Xenograft Model Antitumor Assays	2013
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nature communications, 2013, Volume: 4 Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Hydrazones; Inhibitory Concentration 50; Isomerism; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Neoplasms; Small Molecule Libraries; Survival Analysis; Transcription, Genetic	2013
Surface charge-switchable polymeric magnetic nanoparticles for the controlled release of anticancer drug. ACS applied materials & interfaces, 2013, Aug-14, Volume: 5, Issue:15 Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Physical; Erythrocytes; Hot Temperature; Humans; Hydrogen-Ion Concentration; Lysine; Magnetics; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanoparticles; Neoplasms; Oleic Acid; Paclitaxel; Polymers; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Surface Properties; X-Ray Diffraction	2013
Acetylation control of cancer cell metabolism. Current pharmaceutical design, 2014, Volume: 20, Issue:15 Topics: Acetylation; Animals; Glycolysis; Humans; Lipogenesis; Lysine; Neoplasms; Pyruvate Kinase; Reactive Oxygen Species	2014
An intravascular MRI contrast agent based on Gd(DO3A-Lys) for tumor angiography. Biomaterials, 2014, Volume: 35, Issue:1 Topics: Angiography; Animals; Contrast Media; Female; Gadolinium; Half-Life; Heterocyclic Compounds; Humans; Lysine; Magnetic Resonance Imaging; Mice; Mice, SCID; Neoplasms; Organometallic Compounds; Tissue Distribution	2014
Lysine methylation promotes VEGFR-2 activation and angiogenesis. Science signaling, 2013, Dec-03, Volume: 6, Issue:304 Topics: Animals; Cell Line, Tumor; HEK293 Cells; Heterografts; Humans; Lysine; Methylation; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Protein Processing, Post-Translational; Vascular Endothelial Growth Factor Receptor-2; Zebrafish; Zebrafish Proteins	2013
Protein corona on magnetite nanoparticles and internalization of nanoparticle-protein complexes into healthy and cancer cells. Archives of pharmacal research, 2014, Volume: 37, Issue:1 Topics: Blood Proteins; Cell Culture Techniques; Cell Survival; Endocytosis; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Lysine; Magnetite Nanoparticles; Nanomedicine; Neoplasms; Particle Size; Surface Properties; Time Factors	2014
Structure, functional characterization, and evolution of the dihydroorotase domain of human CAD. Structure (London, England : 1993), 2014, Feb-04, Volume: 22, Issue:2 Topics: Amino Acid Sequence; Aspartate Carbamoyltransferase; Bacterial Proteins; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Catalysis; Catalytic Domain; Cell Line; Dihydroorotase; DNA Repair; Escherichia coli; HEK293 Cells; Histidine; Humans; Hydrogen-Ion Concentration; Ions; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasms; Phosphorylation; Phylogeny; Protein Binding; Protein Multimerization; Sequence Homology, Amino Acid; Zinc	2014
Effect of a nutrient mixture on matrix metalloproteinase-9 dimers in various human cancer cell lines. International journal of oncology, 2014, Volume: 44, Issue:3 Topics: Antioxidants; Ascorbic Acid; Dimerization; Gelatinases; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Lysine; Matrix Metalloproteinase 9; Neoplasms; Proline; Urokinase-Type Plasminogen Activator	2014
Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses. Biochemical and biophysical research communications, 2014, Jan-31, Volume: 444, Issue:1 Topics: Acetylation; Amino Acid Sequence; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; HCT116 Cells; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Molecular Sequence Data; Neoplasms; RNA, Small Interfering; Sirtuin 1	2014
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Molecular cell, 2014, Feb-20, Volume: 53, Issue:4 Topics: Acetyl-CoA C-Acetyltransferase; Animals; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lysine; Male; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Neoplasms; Phosphorylation; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Sirtuin 3; Tyrosine	2014
Should a BRCA2 stop codon human variant, usually considered a polymorphism, be classified as a predisposing mutation? Cancer, 2014, May-15, Volume: 120, Issue:10 Topics: Aged; BRCA2 Protein; Breast Neoplasms; Codon, Terminator; Female; Genetic Predisposition to Disease; Genotype; Germ-Line Mutation; Humans; Lysine; Male; Middle Aged; Neoplasms; Polymorphism, Genetic	2014
Mechanisms of buffer therapy resistance. Neoplasia (New York, N.Y.), 2014, Volume: 16, Issue:4 Topics: Animals; Buffers; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Lysine; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasms	2014
In silico investigation of potential pyruvate kinase M2 regulators from traditional Chinese medicine against cancers. BioMed research international, 2014, Volume: 2014 Topics: Asparagine; Binding Sites; Carrier Proteins; Chemistry, Pharmaceutical; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Ligands; Lysine; Medicine, Chinese Traditional; Membrane Proteins; Mitosis; Molecular Dynamics Simulation; Neoplasms; Protein Conformation; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tryptophan	2014
Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. The Journal of biological chemistry, 2014, Oct-17, Volume: 289, Issue:42 Topics: Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Humans; Lysine; Mass Spectrometry; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteolysis; Proteomics; RNA Interference; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin Thiolesterase; Ubiquitin-Protein Ligases; Ubiquitin-Specific Peptidase 7	2014
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. Free radical biology & medicine, 2014, Volume: 76 Topics: Acetylation; Blotting, Western; Cell Proliferation; Fluorescent Antibody Technique; Glucose; Glycolysis; Humans; Immunoprecipitation; Lactic Acid; Lysine; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Phenotype; Protein Processing, Post-Translational; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Reactive Oxygen Species; Sirtuin 3; Tumor Cells, Cultured	2014
iNOS expression in CD4+ T cells limits Treg induction by repressing TGFβ1: combined iNOS inhibition and Treg depletion unmask endogenous antitumor immunity. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Dec-15, Volume: 20, Issue:24 Topics: Animals; Antineoplastic Agents, Alkylating; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cyclophosphamide; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Humans; Lymphocyte Activation; Lymphocyte Depletion; Lymphocytes, Tumor-Infiltrating; Lysine; Mice; Mice, Knockout; Myeloid Cells; Neoplasms; Nitric Oxide Synthase Type II; T-Lymphocytes, Regulatory; Transcription, Genetic; Transforming Growth Factor beta1; Tumor Burden	2014
Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway. Proceedings of the National Academy of Sciences of the United States of America, 2014, Oct-21, Volume: 111, Issue:42 Topics: Alleles; Amino Acid Sequence; Animals; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Extracellular Signal-Regulated MAP Kinases; Genes, ras; Humans; Lysine; MAP Kinase Signaling System; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Neoplasms; raf Kinases; ras Proteins; Sequence Homology, Amino Acid; Tumor Suppressor Protein p53	2014
A pillararene-based ternary drug-delivery system with photocontrolled anticancer drug release. Small (Weinheim an der Bergstrasse, Germany), 2015, Feb-25, Volume: 11, Issue:8 Topics: Antineoplastic Agents; Cell Line, Tumor; Chlorambucil; Drug Carriers; Drug Delivery Systems; Humans; Lysine; Magnetic Resonance Spectroscopy; Micelles; Nanocapsules; Neoplasms; Photochemistry; Prodrugs; Quaternary Ammonium Compounds; Reproducibility of Results; Solubility; Water	2015
A coding single-nucleotide polymorphism in lysine demethylase KDM4A associates with increased sensitivity to mTOR inhibitors. Cancer discovery, 2015, Volume: 5, Issue:3 Topics: Alleles; Antineoplastic Agents; Cell Line; Cell Line, Tumor; DNA Mutational Analysis; Drug Resistance, Neoplasm; Gene Frequency; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms; Open Reading Frames; Polymorphism, Single Nucleotide; Prognosis; Protein Kinase Inhibitors; TOR Serine-Threonine Kinases; Ubiquitination	2015
STAT3-driven transcription depends upon the dimethylation of K49 by EZH2. Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-31, Volume: 112, Issue:13 Topics: Cell Line, Tumor; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Interleukin-6; Lysine; Mutation; Neoplasms; Phosphorylation; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Processing, Post-Translational; Retroviridae; STAT3 Transcription Factor; Transcription, Genetic	2015
Reversible lysine modification on proteins by using functionalized boronic acids. Chemistry (Weinheim an der Bergstrasse, Germany), 2015, May-26, Volume: 21, Issue:22 Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Azides; Boronic Acids; Cell Line; Cell Line, Tumor; Folic Acid; Humans; Imines; Insulin; Lysine; Models, Molecular; Muramidase; Neoplasms; Paclitaxel; Polyethylene Glycols; Proteins	2015
Biological Relevance and Therapeutic Potential of the Hypusine Modification System. The Journal of biological chemistry, 2015, Jul-24, Volume: 290, Issue:30 Topics: Animals; Homeostasis; Humans; Lysine; Mice; Mice, Knockout; Mixed Function Oxygenases; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Biosynthesis; Protein Interaction Maps; Protein Processing, Post-Translational	2015
MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation. EBioMedicine, 2015, Volume: 2, Issue:5 Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Endoplasmic Reticulum-Associated Degradation; Endoribonucleases; Epithelial Cells; Humans; Intracellular Space; Lysine; Mice; Models, Biological; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteolysis; Proto-Oncogene Proteins c-met; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors; Ubiquitination; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; X-Box Binding Protein 1	2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic acids research, 2015, Sep-18, Volume: 43, Issue:16 Topics: Animals; Carcinogenesis; Cell Line; Cell Movement; Cells, Cultured; Humans; Lysine; Mice; Mice, Nude; MicroRNAs; Neoplasms; Phosphorylation; Protein Stability; RNA-Binding Proteins; SUMO-1 Protein; Sumoylation; Ubiquitination	2015
Epigenetic reprogramming in solid tumors: therapeutic implications of EZH2 gain-of-function mutations. Epigenomics, 2015, Volume: 7, Issue:5 Topics: Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Molecular Targeted Therapy; Mutation; Neoplasms; Polycomb Repressive Complex 2	2015
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer. Nature, 2015, Oct-15, Volume: 526, Issue:7573 Topics: Alleles; Anaplastic Lymphoma Kinase; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Introns; Isoenzymes; Lysine; Methylation; Mice; Molecular Sequence Data; Molecular Weight; Neoplasms; NIH 3T3 Cells; Oncogenes; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; RNA Polymerase II; RNA, Messenger; Signal Transduction; Transcription Initiation, Genetic	2015
LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns. Oncotarget, 2015, Nov-24, Volume: 6, Issue:37 Topics: Algorithms; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromatin; Gene Expression Profiling; Gene Ontology; Gene Regulatory Networks; HeLa Cells; Hep G2 Cells; Histones; Humans; K562 Cells; Lysine; Methylation; Models, Genetic; Neoplasms; Promoter Regions, Genetic; RNA, Long Noncoding; RNA, Messenger; Transcription Initiation Site	2015
Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation. Cancer cell, 2015, Nov-09, Volume: 28, Issue:5 Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Nucleotides; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleoside Diphosphate Reductase; RNA Interference; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Xenograft Model Antitumor Assays	2015
ELL targets c-Myc for proteasomal degradation and suppresses tumour growth. Nature communications, 2016, Mar-24, Volume: 7 Topics: Animals; Cell Proliferation; HCT116 Cells; HEK293 Cells; Humans; Lysine; Male; Mice, Nude; Neoplasms; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Proto-Oncogene Proteins c-myc; Rats; Transcription, Genetic; Transcriptional Elongation Factors; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays	2016
Hyaluronan-Lysine Cisplatin Drug Carrier for Treatment of Localized Cancers: Pharmacokinetics, Tolerability, and Efficacy in Rodents and Canines. Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Dogs; Dose-Response Relationship, Drug; Drug Carriers; Female; Humans; Hyaluronic Acid; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Pilot Projects; Rats; Rats, Sprague-Dawley; Treatment Outcome	2016
SCFFbl12 Increases p21Waf1/Cip1 Expression Level through Atypical Ubiquitin Chain Synthesis. Molecular and cellular biology, 2016, 08-15, Volume: 36, Issue:16 Topics: Autoantigens; Cyclin-Dependent Kinase Inhibitor p21; F-Box Proteins; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Lysine; Neoplasms; Proteasome Endopeptidase Complex; Protein Binding; Ubiquitination; Up-Regulation	2016
The neuropilin-1 receptor mediates enhanced tumor delivery of H2K polyplexes. The journal of gene medicine, 2016, Volume: 18, Issue:7 Topics: Amino Acid Sequence; Animals; Antibodies; Cell Line, Tumor; Female; Genetic Therapy; Histidine; Humans; Luciferases; Lysine; Mice, Nude; Neoplasms; Neuropilin-1; Peptides; Transfection; Xenograft Model Antitumor Assays	2016
Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy. Journal of controlled release : official journal of the Controlled Release Society, 2016, 09-10, Volume: 237 Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Line; Cysteine; Drug Carriers; Female; Lysine; Maleimides; Mice; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Serum Albumin, Bovine	2016
The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent. Oncotarget, 2016, Sep-13, Volume: 7, Issue:37 Topics: Animals; Carcinogenesis; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; HeLa Cells; Histone Demethylases; Histones; Humans; Lysine; Mice; Neoplasms; NIH 3T3 Cells; Protein Binding; S Phase Cell Cycle Checkpoints	2016
Optimizing Protonation States for Selective Double-Strand DNA Photocleavage in Hypoxic Tumors: pH-Gated Transitions of Lysine Dipeptides. Journal of medicinal chemistry, 2016, Sep-22, Volume: 59, Issue:18 Topics: Acetylene; Dipeptides; DNA; Humans; Hydrogen-Ion Concentration; Light; Lysine; Neoplasms; Photolysis; Photosensitizing Agents; Protons	2016
A New Chromatin-Cytoskeleton Link in Cancer. Molecular cancer research : MCR, 2016, Volume: 14, Issue:12 Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin	2016
SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. Oncotarget, 2016, Nov-15, Volume: 7, Issue:46 Topics: Cell Membrane; Enzyme Activation; Gene Expression; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; Phosphorylation; Pleckstrin Homology Domains; Proto-Oncogene Proteins c-akt; Signal Transduction; Tyrosine	2016
Alteration of histone H3 lysine 9 dimethylation in peripheral white blood cells of septic patients with trauma and cancer. Molecular medicine reports, 2016, Volume: 14, Issue:6 Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Female; Fluorescent Antibody Technique; Histones; Humans; Leukocytes; Lysine; Male; Methylation; Middle Aged; Neoplasms; ROC Curve; Sepsis; Wounds and Injuries	2016
Suppression of bromodomain-containing protein 4 by shRNA: A new approach for cancer treatment. Clinical and investigative medicine. Medecine clinique et experimentale, 2016, 12-01, Volume: 39, Issue:6 Topics: Antineoplastic Agents; Cell Cycle Proteins; Cloning, Molecular; Gene Expression Regulation, Neoplastic; Genetic Therapy; Genome, Human; HEK293 Cells; HeLa Cells; Hep G2 Cells; HT29 Cells; Humans; Lysine; MCF-7 Cells; Neoplasms; Nuclear Proteins; Plasmids; Protein Domains; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Transcription Factors; Transcriptional Activation	2016
Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature, 2017, 02-23, Volume: 542, Issue:7642 Topics: beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; DNA Helicases; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Essential; Glycogen Synthase Kinase 3 beta; Histones; Humans; Lysine; Male; Methylation; Molecular Targeted Therapy; Neoplasms; NF-kappa B; Phosphorylation; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Stability; Proteolysis; PTEN Phosphohydrolase; Tumor Necrosis Factor-alpha; Ubiquitination	2017
Intragenic DNA methylation prevents spurious transcription initiation. Nature, 2017, 03-02, Volume: 543, Issue:7643 Topics: Animals; Cell Line; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Genes; Histone-Lysine N-Methyltransferase; Histones; Lysine; Mice; Mouse Embryonic Stem Cells; Neoplasms; Polyadenylation; Ribosomes; RNA Caps; RNA Polymerase II; RNA Stability; RNA, Messenger; Transcription Initiation Site; Transcription Initiation, Genetic	2017
Chromatin reader ZMYND8 is a key target of all trans retinoic acid-mediated inhibition of cancer cell proliferation. Biochimica et biophysica acta. Gene regulatory mechanisms, 2017, Volume: 1860, Issue:4 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Fluorescent Antibody Technique; Histone Deacetylases; Histones; Humans; Lysine; Methylation; Mice; Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors for Activated C Kinase; Receptors, Cell Surface; Response Elements; RNA Polymerase II; Time Factors; Tretinoin; Tumor Suppressor Proteins; YY1 Transcription Factor	2017
Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. Journal of molecular biology, 2008, Jul-04, Volume: 380, Issue:2 Topics: Apoptosis; Crystallography, X-Ray; DNA Repair; Histones; Humans; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasms; Nuclear Proteins; Peptides; Protein Array Analysis; Protein Binding; Protein Structure, Tertiary; Tumor Suppressor Proteins	2008
Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry, 2008, Nov-25, Volume: 47, Issue:47 Topics: 3T3 Cells; Animals; Cattle; Cell Membrane; Cell Survival; Glutamic Acid; Humans; Kinetics; Lysine; Mice; Microscopy, Fluorescence; Mutation; Neoplasms; Oncogenes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Substrate Specificity	2008
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science (New York, N.Y.), 2008, Dec-12, Volume: 322, Issue:5908 Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors	2008
Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation. Autonomic neuroscience : basic & clinical, 2009, May-11, Volume: 147, Issue:1-2 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arginine; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Immune Tolerance; Immunologic Factors; Killer Cells, Natural; Lysine; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neuroimmunomodulation; Rats; Rats, Wistar; Spleen; Sympathetic Nervous System; Treatment Outcome	2009
PRIP promotes tumor formation through enhancing serum-responsive factor-mediated FOS expression. The Journal of biological chemistry, 2009, May-22, Volume: 284, Issue:21 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mammary Neoplasms, Animal; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Receptor Coactivators; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-fos; ras Proteins; Serum Response Factor	2009
Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers. Gene, 2009, May-01, Volume: 436, Issue:1-2 Topics: Acetylation; Binding Sites; Blotting, Western; Breast Neoplasms; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histones; Humans; Immunohistochemistry; Kidney Neoplasms; Lysine; Male; Neoplasms; Nucleosomes; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Recombinant Proteins; Tissue Array Analysis; Urinary Bladder Neoplasms	2009
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity. Cancer research, 2009, May-15, Volume: 69, Issue:10 Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine	2009
Constructing bioactive peptides with pH-dependent activities. Peptides, 2009, Volume: 30, Issue:8 Topics: Amino Acid Sequence; Animals; Arginine; Cell Death; Cell Line; Fluoresceins; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Mice; Mice, Nude; Micelles; Neoplasms; Peptides; Structure-Activity Relationship; Transplantation, Homologous	2009
C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy. Journal of the American Chemical Society, 2009, Aug-19, Volume: 131, Issue:32 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Cleavage; Humans; Hydrogen-Ion Concentration; Light; Lysine; Models, Molecular; Molecular Structure; Neoplasms; Photolysis; Plasmids	2009
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Molecular cell, 2009, Aug-28, Volume: 35, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; RNA Interference; SKP Cullin F-Box Protein Ligases; Stress, Physiological; Time Factors; Ubiquitination	2009
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival. Nature, 2010, Jan-07, Volume: 463, Issue:7277 Topics: Animals; Apoptosis; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Cell Survival; DNA Damage; Docetaxel; Etoposide; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Half-Life; Humans; Lysine; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Nitrophenols; Phosphorylation; Piperazines; Polyubiquitin; Prognosis; Protein Binding; Protein Stability; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Sulfonamides; Taxoids; Ubiquitin Thiolesterase; Ubiquitination; Ultraviolet Rays; Xenograft Model Antitumor Assays	2010
[Biosynthesis of L-lysine-alpha-oxidase, an antitumor enzyme, by Trichoderma spp]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2009, Volume: 54, Issue:5-6 Topics: Amino Acid Oxidoreductases; Animals; Antineoplastic Agents; Brevibacterium; Fungal Proteins; Humans; Lysine; Neoplasms; Trichoderma	2009
G9a and Glp methylate lysine 373 in the tumor suppressor p53. The Journal of biological chemistry, 2010, Mar-26, Volume: 285, Issue:13 Topics: Autoantigens; DNA Damage; DNA Methylation; Gene Expression Regulation; Golgi Matrix Proteins; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; Peptides; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; RNA, Small Interfering; Tumor Suppressor Protein p53	2010
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. Oncogene, 2010, Apr-15, Volume: 29, Issue:15 Topics: Acetylation; Animals; Cell Death; Cell Line, Tumor; DNA Damage; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Male; Neoplasms; Sirtuin 1; Topoisomerase II Inhibitors; Valproic Acid	2010
The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Molecular and cellular biology, 2010, Volume: 30, Issue:10 Topics: Adaptor Proteins, Vesicular Transport; Animals; Calcium-Binding Proteins; Cell Cycle; Drosophila melanogaster; Drosophila Proteins; Histones; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Lysine; Membrane Proteins; Mutation; Neoplasms; Oxidoreductases, N-Demethylating; Phenotype; Photoreceptor Cells, Invertebrate; Pigmentation; Receptors, Notch; Recombinant Fusion Proteins; RNA Interference; Serrate-Jagged Proteins	2010
Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice. The Journal of biological chemistry, 2010, Sep-03, Volume: 285, Issue:36 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Cycle; Chromatin; Cyclin E; Gene Expression Regulation; Gene Knockout Techniques; Growth and Development; HeLa Cells; Histones; Humans; Longevity; Lymphopoiesis; Lysine; Male; Methylation; Mice; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Repressor Proteins; Survival Rate; Tumor Suppressor Proteins	2010
Negative regulation of hypoxic responses via induced Reptin methylation. Molecular cell, 2010, Jul-09, Volume: 39, Issue:1 Topics: Animals; ATPases Associated with Diverse Cellular Activities; Carrier Proteins; Cell Hypoxia; Cell Line; DNA Helicases; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Methylation; Mice; Models, Biological; Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Binding; Xenograft Model Antitumor Assays	2010
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines. Oncology reports, 2010, Volume: 24, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate	2010
Cationic polymer-mediated small interfering RNA delivery for P-glycoprotein down-regulation in tumor cells. Cancer, 2010, Dec-01, Volume: 116, Issue:23 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cations; Cell Line, Tumor; Down-Regulation; Doxorubicin; Drug Resistance, Multiple; Feasibility Studies; Gene Transfer Techniques; Humans; Lysine; Neoplasms; Paclitaxel; Polymers; RNA, Small Interfering	2010
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Molecular and cellular biology, 2010, Volume: 30, Issue:22 Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; ATPases Associated with Diverse Cellular Activities; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatin; DNA-Binding Proteins; E2F Transcription Factors; Epigenesis, Genetic; Genes, Reporter; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Protein Isoforms; RNA, Small Interfering; Sequence Alignment; Transcriptional Activation	2010
Lysine methylation of promoter-bound transcription factors and relevance to cancer. Cell research, 2011, Volume: 21, Issue:3 Topics: DNA; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; NF-kappa B; Promoter Regions, Genetic; STAT3 Transcription Factor	2011
Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. Cold Spring Harbor symposia on quantitative biology, 2010, Volume: 75 Topics: Cell Differentiation; Cellular Senescence; Gene Expression Regulation; Genome, Human; Histone Demethylases; Histones; Homeodomain Proteins; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Neoplasms; Nuclear Proteins; Transcription, Genetic	2010
Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. The Journal of biological chemistry, 2011, Mar-25, Volume: 286, Issue:12 Topics: Cell Survival; Endopeptidases; HEK293 Cells; HeLa Cells; Histone Deacetylases; Humans; Lysine; Neoplasm Proteins; Neoplasms; Repressor Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Ubiquitination	2011
Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker. Journal of controlled release : official journal of the Controlled Release Society, 2011, Jun-10, Volume: 152, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Dendrimers; Doxorubicin; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Lysine; Male; Neoplasms; Polyethylene Glycols; Polylysine; Rats; Rats, Sprague-Dawley	2011
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex. Nanomedicine : nanotechnology, biology, and medicine, 2011, Volume: 7, Issue:5 Topics: Animals; Arginine; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Humans; Leucine; Lysine; Mice; Mice, Inbred BALB C; Neoplasms; Polyethyleneimine	2011
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex. Biomaterials, 2011, Volume: 32, Issue:25 Topics: Animals; Arginine; Female; Gene Expression; Humans; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasms; Polypropylenes	2011
siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. Pharmaceutical research, 2011, Volume: 28, Issue:10 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Down-Regulation; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Lysine; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms; Polyethyleneimine; Polymers; RNA, Small Interfering; Stearic Acids; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2011
And-1 is required for the stability of histone acetyltransferase Gcn5. Oncogene, 2012, Feb-02, Volume: 31, Issue:5 Topics: Acetylation; Cell Cycle; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA-Binding Proteins; HCT116 Cells; HEK293 Cells; HeLa Cells; Histones; Humans; Immunoblotting; Lysine; Neoplasms; p300-CBP Transcription Factors; Protein Binding; Protein Stability; RNA Interference	2012
Differences in DNA condensation and release by lysine and arginine homopeptides govern their DNA delivery efficiencies. Molecular pharmaceutics, 2011, Oct-03, Volume: 8, Issue:5 Topics: Animals; Arginine; Biological Transport; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Packaging; DNA-Binding Proteins; DNA, Neoplasm; DNA, Viral; Gene Transfer Techniques; Genetic Vectors; Humans; Lysine; Molecular Weight; Neoplasms; Nucleic Acid Conformation; Oligopeptides; Particle Size; Peptides; Structure-Activity Relationship	2011
The ubiquitin clan: A protein family essential for life. FEBS letters, 2011, Sep-16, Volume: 585, Issue:18 Topics: Animals; Diabetes Mellitus, Type 2; Humans; Lysine; Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Ubiquitin; Ubiquitination	2011
Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation. The Journal of biological chemistry, 2011, Nov-04, Volume: 286, Issue:44 Topics: Calorimetry; Cell Line, Tumor; Crystallography, X-Ray; Genes, Tumor Suppressor; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Lysine; Methylation; Molecular Conformation; Neoplasms; Protein Binding; Transcription, Genetic; Tumor Suppressor Protein p53	2011
Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase. Biochemistry, 2011, Nov-29, Volume: 50, Issue:47 Topics: Amphibian Proteins; Animals; Antineoplastic Agents; Arginine; Humans; K562 Cells; Lysine; Models, Molecular; Neoplasms; Rana pipiens; Ribonucleases	2011
Maspin increases Ku70 acetylation and Bax-mediated cell death in cancer cells. International journal of molecular medicine, 2012, Volume: 29, Issue:2 Topics: Acetylation; Antigens, Nuclear; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; Cytoplasm; DNA-Binding Proteins; HEK293 Cells; HeLa Cells; Humans; Ku Autoantigen; Lysine; Neoplasms; Protein Binding; Protein Transport; Serpins	2012
Histone deacetylase inhibitors in the therapy of cancer: much to learn. Epigenomics, 2010, Volume: 2, Issue:6 Topics: Cell Death; Cell Movement; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Lysine; Neoplasms	2010
RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility. The Journal of biological chemistry, 2012, Apr-20, Volume: 287, Issue:17 Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Dissociation Inhibitors; Humans; Lysine; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; rho GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Sumoylation; Wound Healing; X-Linked Inhibitor of Apoptosis Protein	2012
A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery. Biomaterials, 2012, Volume: 33, Issue:17 Topics: Amines; Animals; Cell Death; Cell Line, Tumor; Chromatography, Gel; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Flow Cytometry; Gene Transfer Techniques; Humans; Hydroxylation; Lysine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Particle Size; Polyesters; Polyethylene Glycols; Polylysine; Polymerization; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared	2012
Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells. Biochemical and biophysical research communications, 2012, Aug-03, Volume: 424, Issue:3 Topics: Acetylation; Acrylamides; Apoptosis; Cell Cycle; Cytokines; Enzyme Inhibitors; Gene Knockdown Techniques; HEK293 Cells; Humans; Lysine; Metabolic Networks and Pathways; Neoplasms; Nicotinamide Phosphoribosyltransferase; Piperidines; Simian virus 40; Sirtuin 1; Tumor Suppressor Protein p53	2012
Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells. Carcinogenesis, 2012, Volume: 33, Issue:12 Topics: Aging; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Colitis; Colon; Death-Associated Protein Kinases; Dextran Sulfate; Epithelial Cells; Gene Expression; Histones; Intestinal Mucosa; Lysine; Male; Methylation; Mice; Mice, Inbred BALB C; Neoplasms	2012
Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49 Topics: Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Lysine; Neoplasms; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; ras Proteins; RNA, Small Interfering; Signal Transduction	2012
Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell reports, 2013, Jan-31, Volume: 3, Issue:1 Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; DNA Helicases; Genetic Loci; Genome; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasms; Neuroblastoma; Peptides; Protein Binding; Structure-Activity Relationship	2013
Surface-modified HK:siRNA nanoplexes with enhanced pharmacokinetics and tumor growth inhibition. Biomacromolecules, 2013, Mar-11, Volume: 14, Issue:3 Topics: Animals; Cell Line, Tumor; Female; Gene Expression; Gene Silencing; Histidine; Humans; Lysine; Mice; Nanostructures; Neoplasms; Proto-Oncogene Proteins c-raf; RNA, Small Interfering; Xenograft Model Antitumor Assays	2013
Malignant tumor disease as a sub-chronic, progressive intoxication on the basis of the perpetuation of the release of amino acids, initiated by a retrograde-differentiated muscle degradation protease. Medical hypotheses, 2002, Volume: 59, Issue:5 Topics: Amino Acids; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Progression; Endopeptidases; Humans; Lysine; Models, Biological; Muscle Proteins; Muscle, Skeletal; Neoplasm Proteins; Neoplasms; Nutrition Disorders	2002
Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells. Nucleic acids research, 2002, Nov-01, Volume: 30, Issue:21 Topics: Acetylation; Cadherins; Chromatin; Chromosomal Proteins, Non-Histone; CpG Islands; DNA Methylation; DNA-Binding Proteins; Gene Silencing; Histones; Humans; Lysine; Methyl-CpG-Binding Protein 2; Methylation; Neoplasms; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Tumor Cells, Cultured	2002
8-Hydroxylysine: an inhibitor of glutamine and protein synthesis by the Ehrlich ascites carcinoma cell. Cancer research, 1957, Volume: 17, Issue:9 Topics: Ascites; Glutamine; Hydroxylysine; Lysine; Neoplasms; Protein Biosynthesis; Proteins	1957
Labeling of histones and other nuclear proteins with L-lysine-U-C14 in tissues of tumor-bearing rats. Cancer research, 1958, Volume: 18, Issue:8 Part 1 Topics: Animals; Encephalomyelitis; Histones; Lysine; Neoplasms; Nuclear Proteins; Nucleoproteins; Rats	1958
Labeling of nuclear proteins of tumors and other tissues in vitro with L-lysine-U-C14 and L-alanine-U-C14. Acta - Unio Internationalis Contra Cancrum, 1960, Volume: 16 Topics: Alanine; Biochemical Phenomena; Humans; In Vitro Techniques; Lysine; Neoplasms; Nuclear Proteins; Nucleoproteins	1960
The effect of hydroxylysine on ascites cell growth in vitro. Experimental cell research, 1963, Volume: 29 Topics: Ascites; Cell Cycle; Cell Proliferation; Hydroxylysine; In Vitro Techniques; Lysine; Neoplasms; Neoplasms, Experimental	1963
The isolation of intermediary metabolites of L-lysine-U-C14 from tissues of tumor-bearing rats. Cancer research, 1963, Volume: 23 Topics: Animals; Lysine; Neoplasms; Neoplasms, Experimental; Rats	1963
ANALYSIS OF PEPTIDES OF THE MOCERATELY LYSINE RICH HISTONE FRACTION, F2B, OF THE WALKER TUMOR AND OTHER TISSUES. Experimental cell research, 1963, Volume: 88 Topics: Animals; Carcinoma 256, Walker; Chromatography; Electrophoresis; Histones; Lysine; Neoplasm Proteins; Neoplasms; Peptides; Research	1963
BIOCHEMISTRY OF HISTONES AND THE CELL CYCLE. Journal of cellular and comparative physiology, 1963, Volume: 62 Topics: Animals; Carbon Isotopes; Carcinoma 256, Walker; Cell Division; Cell Nucleus; Chromatography; DNA; DNA, Neoplasm; Electrophoresis; Histones; Lysine; Neoplasm Proteins; Neoplasms; Research	1963
STUDIES ON ACIDIC NUCLEAR PROTEINS OF THE WALKER TUMOR AND LIVER. Cancer research, 1963, Volume: 23 Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma 256, Walker; DNA; DNA, Neoplasm; Liver; Lysine; Neoplasms; Neoplasms, Experimental; Nuclear Proteins; Nucleoproteins; Proteins; Rats; Research; RNA; RNA, Neoplasm	1963
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-04, Volume: 257 Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine	1963
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS. Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51 Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research	1964
INCORPORATION OF 8-AZAGUANINE AND GROWTH INHIBITION IN MAMMALIAN SPINNER CULTURES. Experimental cell research, 1964, Volume: 34 Topics: Azaguanine; Carbon Isotopes; Cell Biology; DNA; DNA, Neoplasm; Guanine; Lysine; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Pharmacology; Proteins; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques; Urethane	1964
AN EXPERIMENTAL STUDY OF TISSUE-CONCENTRATION RATIOS OF AS74 ARSENATE AND LABELED ORGANIC CONJUGATES. Journal of neurosurgery, 1964, Volume: 21 Topics: Animals; Arsenates; Arsenic; Arsenicals; Azo Compounds; Brain Neoplasms; Ependymoma; Lysine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Research	1964
[DIAGNOSTIC VALUE OF TOLBUTAMIDE AND 1-LYSINE IN INSULAR ADENOMA OF THE PANCREAS]. Revista argentina de endocrinologia y metabolismo, 1964, Volume: 10 Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hypoglycemia; Lysine; Neoplasms; Pancreatic Neoplasms; Pharmacology; Tolbutamide	1964
EXPERIMENTAL AND CLINICAL EVALUATION OF ARGINASE INHIBITOR IN CHRONIC URINARY OBSTRUCTION. The Journal of the International College of Surgeons, 1965, Volume: 43 Topics: Arginase; Biomedical Research; Dogs; Enzyme Inhibitors; Humans; Lysine; Male; Neoplasms; Preoperative Care; Prostatic Hyperplasia; Prostatic Neoplasms; Research; Uremia; Urethral Stricture; Urinary Bladder Neck Obstruction; Urologic Diseases	1965
THE UPTAKE OF DIFFERENTIALLY COUPLED 74-AS-ARSANO-POLY-L-LYSINE IN TUMOR-BEARING MOUSE TISSUES. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1964, Volume: 5 Topics: Animals; Arsenicals; Blood; Dialysis; Kidney; Liver; Lysine; Mice; Neoplasms; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Renal Dialysis; Research	1964
Antibiotic activity of Leu-Lys rich model peptides. Biotechnology letters, 2003, Volume: 25, Issue:16 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Erythrocytes; Fungi; Hemolysis; Humans; Leucine; Lysine; Microbial Sensitivity Tests; Neoplasms; Peptide Fragments	2003
Formation of acrolein-derived 2'-deoxyadenosine adduct in an iron-induced carcinogenesis model. The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50 Topics: Acrolein; Aldehydes; Animals; Antibodies, Monoclonal; Binding, Competitive; Cattle; Cell Nucleus; Deoxyadenosines; DNA Adducts; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Ions; Iron; Lipid Peroxidation; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Chemical; Neoplasms; Oxidative Stress; Oxygen; Peroxidase; Rats; Rats, Wistar; Threonine; Thymus Gland; Time Factors	2003
Three dimensional analysis of histone methylation patterns in normal and tumor cell nuclei. European journal of histochemistry : EJH, 2004, Volume: 48, Issue:1 Topics: Cell Line, Tumor; Cell Nucleus; Centromere; DNA; Female; Fibroblasts; Heterochromatin; Histones; Humans; Lysine; Methylation; Monocytes; Neoplasms; T-Lymphocytes	2004
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex. The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9 Topics: Actins; Anaphase-Promoting Complex-Cyclosome; Antibodies, Monoclonal; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine; Lysine; Models, Molecular; Mutation; Mutation, Missense; Neoplasms; Peptides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Time Factors; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein	2005
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nature genetics, 2005, Volume: 37, Issue:4 Topics: Acetylation; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lymphocytes; Lysine; Neoplasms; Promoter Regions, Genetic; Protein Processing, Post-Translational; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured	2005
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine. Annals of the New York Academy of Sciences, 2005, Volume: 1043 Topics: Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycolysis; Humans; Lysine; Neoplasm Proteins; Neoplasms; Pyruvaldehyde	2005
Radioimmunotherapy of solid tumors by targeting extra domain B fibronectin: identification of the best-suited radioimmunoconjugate. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 2 Topics: Animals; Bone Marrow; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dimerization; Electrophoresis, Polyacrylamide Gel; Fibronectins; Humans; Immunoconjugates; Immunoglobulin Fragments; Immunoglobulin G; Lysine; Mice; Neoplasms; Pentetic Acid; Protein Structure, Tertiary; Radioimmunotherapy; Radiometry; Time Factors	2005
Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells. The FEBS journal, 2006, Volume: 273, Issue:6 Topics: Base Sequence; Cell Line; Cell Line, Tumor; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Molecular Sequence Data; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Polyadenylation; Polyribosomes; Protein Biosynthesis; Protein Isoforms; Protein Precursors; Protein Processing, Post-Translational; RNA-Binding Proteins; RNA, Messenger; Transfection	2006
PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. Journal of controlled release : official journal of the Controlled Release Society, 2006, Dec-01, Volume: 116, Issue:3 Topics: Animals; Dendrimers; Drug Carriers; Injections, Intravenous; Liver; Lysine; Male; Mice; Mice, Inbred Strains; Neoplasms; Polyethylene Glycols; Spleen; Tissue Distribution	2006
Amifostine protects rat kidneys during peptide receptor radionuclide therapy with [177Lu-DOTA0,Tyr3]octreotate. European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:5 Topics: Amifostine; Animals; Body Weight; Creatinine; Kidney; Lysine; Male; Neoplasms; Octreotide; Organometallic Compounds; Proteinuria; Radiation Injuries; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Tomography, Emission-Computed, Single-Photon	2007
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nature genetics, 2007, Volume: 39, Issue:2 Topics: Caco-2 Cells; Carrier Proteins; Cells, Cultured; Colonic Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Methyltransferases; Neoplasms; Viral Envelope Proteins	2007
Differentially expressed genes are marked by histone 3 lysine 9 trimethylation in human cancer cells. Oncogene, 2008, Apr-10, Volume: 27, Issue:17 Topics: Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Neoplasms; Otx Transcription Factors; Transcription, Genetic	2008
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Molecular cell, 2008, Feb-29, Volume: 29, Issue:4 Topics: Amino Acid Sequence; Binding Sites; Cell Line; Crystallography, X-Ray; Deubiquitinating Enzyme CYLD; Genes, Tumor Suppressor; Humans; JNK Mitogen-Activated Protein Kinases; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasms; NF-kappa B; Polyubiquitin; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Substrate Specificity; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7; Zinc	2008
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias. British journal of cancer, 2008, May-06, Volume: 98, Issue:9 Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms	2008
[Multiple post-translational modifications implied in the gene expression regulation: example of the sumoylation of Ets factors]. Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007, Volume: 162, Issue:5-6 Topics: Acetylation; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Leukemia; Lysine; Mice; Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Protein c-ets-1; SUMO-1 Protein; Ubiquitin	2007
Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells. PloS one, 2008, Apr-30, Volume: 3, Issue:4 Topics: Cell Line, Tumor; Centrosome; Chromosomal Instability; Cyclin-Dependent Kinase Inhibitor p16; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methyltransferases; Neoplasms; Protein Methyltransferases; Repressor Proteins; Telomere; Tumor Suppressor Proteins	2008
Aminoaciduria resulting from cycloleucine administration in man. Science (New York, N.Y.), 1967, Jul-28, Volume: 157, Issue:3787 Topics: Amino Acids; Arginine; Cystinuria; Humans; Kidney Tubules; Lysine; Neoplasms; Ornithine	1967
Small intrathecal doses of lysine-acetylsalicylate relieve intractable pain in man. The Journal of international medical research, 1983, Volume: 11, Issue:2 Topics: Analgesics; Aspirin; Back Pain; Drug Evaluation; Humans; Injections, Spinal; Lysine; Neoplasms; Pain, Intractable	1983
The living state and cancer. Physiological chemistry and physics, 1980, Volume: 12, Issue:2 Topics: Aldehydes; Ascorbic Acid; Biological Evolution; Chemical Phenomena; Chemistry; Electric Conductivity; Electron Spin Resonance Spectroscopy; Electron Transport; Ethylenediamines; Glutathione; Lysine; Methylamines; Mixed Function Oxygenases; Neoplasms; Origin of Life; Oxygen; Proteins; Pyruvaldehyde	1980
Apparent methionine auxotrophy of some tumour cell lines may be linked to impaired amino acid transport. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12 Topics: Animals; Biological Transport; Carcinoma 256, Walker; Cell Division; Cell Line; Embryo, Mammalian; Fibroblasts; Humans; Leukemia, Experimental; Lysine; Methionine; Mice; Neoplasms; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms	1981
Researchers develop ceramic drug delivery system. Journal of the Mississippi State Medical Association, 1995, Volume: 36, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Animals; Calcium Phosphates; Drug Implants; Humans; Lysine; Neoplasms; Osteoporosis	1995
Cyclooxygenase inhibitors prevent the induction of tolerance to the toxic effects of tumor necrosis factor. Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy, 1993, Volume: 14, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Protocols; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Immunotherapy; Indomethacin; Lysine; Mice; Mice, Inbred C57BL; Neoplasms; Piroxicam; Recombinant Proteins; Tumor Necrosis Factor-alpha	1993
Improved renal clearance and tumor targeting of 99mTc-labeled anti-Tac monoclonal antibody Fab by chemical modifications. Nuclear medicine and biology, 2002, Volume: 29, Issue:2 Topics: Animals; Antibodies, Monoclonal; Female; Glycolates; Hydrogen-Ion Concentration; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Kidney; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Mertiatide; Tissue Distribution	2002
Multiple lysine mutations in the C-terminus of p53 make it resistant to degradation mediated by MDM2 but not by human papillomavirus E6 and induce growth inhibition in MDM2-overexpressing cells. Oncogene, 2002, Apr-11, Volume: 21, Issue:16 Topics: Base Sequence; Cell Division; Humans; Lysine; Mutation; Neoplasms; Nuclear Proteins; Oncogene Proteins, Viral; Papillomaviridae; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2002
[Analgesic action of lysine acetylsalicylate in intravenous administration on pain caused by cancer]. Minerva anestesiologica, 1975, Volume: 41, Issue:12 Topics: Aspirin; Humans; Lysine; Neoplasms; Pain, Intractable; Palliative Care	1975
Differences in uptake of aminoacids by patients with various forms of cancer. Neoplasma, 1978, Volume: 25, Issue:5 Topics: Amino Acids; Female; Humans; Lysine; Male; Neoplasm Metastasis; Neoplasms; Valine	1978
[A new method for the detection of sensitized lymphocytes in malignant diseases--PAL test]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Hemagglutination Tests; Humans; Lymphocytes; Lysine; Neoplasms; Oligopeptides	1978
Diagnostic meaning of the urinary output of Nepsilon-methylated lysines. Investigation of healthy individuals and patients with malignant diseases, myopathies or renal failure. Clinica chimica acta; international journal of clinical chemistry, 1975, Jan-20, Volume: 58, Issue:2 Topics: Adolescent; Adult; Child; Diagnosis, Differential; Female; Humans; Infant; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Muscular Diseases; Neoplasms; Tritium	1975
Heterogeneity of heat response in murine, canine and human tumors: influence on predictive assays. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:3 Topics: Animals; Cell Survival; Dogs; Humans; Hyperthermia, Induced; Lysine; Mice; Neoplasms; Neoplasms, Experimental; Temperature; Thermodynamics; Thermography	1991
Recovery of low thymic hormone levels in cancer patients by lysine-arginine combination. International journal of immunopharmacology, 1990, Volume: 12, Issue:4 Topics: Adult; Aged; Arginine; Drug Combinations; Female; Humans; Lysine; Male; Middle Aged; Neoplasms; T-Lymphocytes; Thymic Factor, Circulating; Thymus Hormones	1990
A predictive assay for human tumor cellular response to hyperthermia using dansyl lysine staining and flow cytometry. International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:2 Topics: Biopsy; Cell Survival; Flow Cytometry; Fluorescence; Humans; Hyperthermia, Induced; Lysine; Neoplasms; Staining and Labeling	1988
[Chronic refractory pain in cancer patients. Value of the spinal injection of lysine acetylsalicylate. 60 cases]. Presse medicale (Paris, France : 1983), 1987, Sep-19, Volume: 16, Issue:30 Topics: Adult; Aged; Analgesics; Aspirin; Chronic Disease; Female; Humans; Injections, Spinal; Lysine; Male; Middle Aged; Neoplasms; Pain	1987
[Analgesia with an implanted device for repetitive intrathecal injections of morphine]. Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:6 Topics: Adolescent; Adult; Aged; Aspirin; Chronic Disease; Clonidine; Drug Tolerance; Humans; Injections, Spinal; Lysine; Middle Aged; Morphine; Neoplasms; Pain; Receptors, Opioid	1985
H1(0) histones of normal and cancer human cells. Amino acid composition of H1 purified by polyacrylamide gel electrophoresis. Molecular and cellular biochemistry, 1986, Volume: 71, Issue:2 Topics: Amino Acids; Arginine; Carcinoma, Hepatocellular; Cell Line; Histones; Humans; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lysine; Neoplasms	1986
Fasting plasma amino acid levels in cancer patients. Cancer, 1985, Sep-01, Volume: 56, Issue:5 Topics: Adolescent; Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Esophageal Neoplasms; Fasting; Female; Humans; Lysine; Male; Middle Aged; Neoplasms; Tyrosine	1985
[Comparative study of the analgesic activity of 1 g injectable Aspegic and injectable Noramidopyrine]. Revue d'odonto-stomatologie du midi de la France, 1985, Volume: 43, Issue:4 Topics: Adult; Aged; Aminopyrine; Analgesics; Aspirin; Dipyrone; Female; Humans; Lysine; Male; Middle Aged; Neoplasms; Pain, Postoperative; Pyrazolones; Surgery, Plastic	1985
Fibrinogen and metastases. Journal of medicine, 1974, Volume: 5, Issue:1 Topics: Animals; Cell Line; Culture Media; Female; Fibrinogen; gamma-Glutamyltransferase; Humans; In Vitro Techniques; Lysine; Mitochondria; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Oxygen Consumption; Plasmacytoma; Pregnancy; Thrombin; Thrombosis; Wound Healing	1974
Learning and memory in the immune response. Cancer research, 1966, Volume: 26, Issue:9 Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Dinitrophenols; gamma-Globulins; Lysine; Neoplasms; Rabbits	1966
Beta2-microglobulin: occurrence in fetal life and malignancy. Clinica chimica acta; international journal of clinical chemistry, 1974, May-17, Volume: 52, Issue:3 Topics: Aging; Carbon Radioisotopes; Female; Fetal Proteins; Fetus; Gestational Age; Humans; Immunodiffusion; Infant, Newborn; Infant, Premature; Isoleucine; Leukemia; Lysine; Maternal-Fetal Exchange; Neoplasms; Pregnancy; Serum Globulins; Umbilical Cord	1974
Nature of lymphocyte-tumor interaction. A general method for cellular immunoabsorption. The Journal of experimental medicine, 1973, Apr-01, Volume: 137, Issue:4 Topics: Animals; Ascitic Fluid; Calcium; Cell Adhesion; Chromium Isotopes; Hemadsorption; Immunity, Cellular; Immunologic Techniques; Leukemia, Experimental; Lymphocytes; Lysine; Magnesium; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred BALB C; Neoplasms	1973
Comparative high-resolution electrophoresis of tumor histones: variation in phosphorylation as a function of cell replication rate. Cancer research, 1972, Volume: 32, Issue:8 Topics: Alkaline Phosphatase; Animals; Densitometry; Electrophoresis, Disc; Histones; Lysine; Methods; Mice; Mice, Inbred Strains; Mitosis; Neoplasms; Neoplasms, Experimental; Phosphoric Acids; Rats; Rats, Inbred Strains; Time Factors	1972
Immunosuppressive effects of L-asparaginase. Cancer research, 1970, Volume: 30, Issue:6 Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine	1970
Occurrence of L-lysine dehydrogenase (LyDH) in human serum in normal and some pathological states. Helvetica medica acta, 1967, Volume: 34, Issue:1 Topics: Adolescent; Adult; Amino Acid Oxidoreductases; Breast Neoplasms; Female; Heart Diseases; Heart Failure; Humans; Kidney Neoplasms; Leukemia, Lymphoid; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Lysine; Male; Middle Aged; Multiple Myeloma; Myocardial Infarction; Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms	1967
[Use of L-103 hydrolysin in malignant tumors]. Voprosy onkologii, 1959, Volume: 5, Issue:5 Topics: Amino Acids; Humans; Neoplasms; Protein Hydrolysates	1959
[CLINICAL USE OF HYDROLYSIN L-103]. Vestnik khirurgii imeni I. I. Grekova, 1963, Volume: 91 Topics: Anaphylaxis; Burns; Humans; Neoplasms; Peptic Ulcer; Protein Hydrolysates	1963