lysine has been researched along with Astrocytoma, Grade IV in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 20 (60.61) | 24.3611 |
| 2020's | 10 (30.30) | 2.80 |
| Authors | Studies |
|---|---|
| Ayyannan, SR; Mitra, R | 1 |
| Amé, JC; Dantzer, F; Hanini, N; Nguekeu-Zebaze, L; Noll, A; Roegel, L; Wadier, N | 1 |
| Alejo, S; Brenner, AJ; Chen, Y; Clarke, K; Gilbert, AR; He, Y; Jayamohan, S; Johnson, JD; Lai, Z; Li, W; Lv, Y; Palacios, BE; Pratap, UP; Sareddy, GR; Suzuki, T; Tekmal, RR; Vadlamudi, RK; Venkata, PP; Viswanadhapalli, S; Weldon, K; Ye, Z; Zhao, W; Zheng, S; Zou, Y | 1 |
| Cai, J; Chen, C; Chen, J; Chen, Z; Fan, Z; Gu, J; Guo, C; Hu, J; Jiang, B; Leng, T; Li, Q; Liang, J; Liang, X; Lin, Y; Liu, X; Mai, J; Sai, K; Sun, S; Wang, J; Xu, J; Yan, G; Yang, W; Yin, W; Zhong, Y; Zhu, W | 1 |
| Guha, C; Sidoli, S; Young, D | 1 |
| Gao, Z; Hu, R; Li, M; Li, Y; Liu, C; Mei, M; Pang, B; Ren, Y; Wang, Y; Yang, J; Zhang, B; Zhang, X; Zhou, X | 1 |
| Jang, JH; Jin, SY; Kim, KH; Kim, MS; Kim, SH; Kim, YZ; Lee, M; Lee, SH; Lee, YS; Nam, TM | 1 |
| Gül, D; Krämer, OH; Reinhardt, C | 1 |
| Barbus, M; Biran, A; Gal, Z; Glass, R; Herold-Mende, C; Mallm, JP; Meshorer, E; Rippe, K; Schumacher, S; Windisch, P | 1 |
| Badodi, S; Barnes, MR; Brandner, S; Ceric, D; Cognolato, E; Gemma, C; Guglielmi, L; Marino, S; Millner, TO; Pomella, N; Ricci, B; Zhang, X; Zhang, Y | 1 |
| Brennum, J; Hamerlik, P; Jensen, KE; Michaelsen, SR; Pedersen, H; Poulsen, HS; Rasmussen, RD; Skjoth-Rasmussen, J; Staberg, M; Villingshøj, M; Vitting-Seerup, K | 1 |
| Li, W; Shi, J; Shi, L; Shi, X; Wen, H | 1 |
| Bao, L; Chen, Y; Chiang, CM; Fontenot, M; Hatanpaa, KJ; Lai, HT; Lega, B; Luo, W; Raisanen, JM; Semenza, GL; Wang, JE; Wang, Y; Wu, SY | 1 |
| Akiyama, T; Echizen, K; Funato, K; Hayashi, T; Ino, Y; Koyama-Nasu, R; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Negishi, L; Saito, N; Shimizu, N; Tabar, V; Todo, T | 1 |
| Bechet, D; Belle, J; Cagnone, G; Chen, CCL; Chen, H; Cheung, WA; De Jay, N; Deshmukh, S; Ellezam, B; Faury, D; Garcia, BA; Harutyunyan, AS; Hu, B; Jabado, N; Jain, SU; Kleinman, CL; Krug, B; Lewis, PW; Li, R; Lu, C; Majewski, J; Marchione, DM; McConechy, MK; Mikael, LG; Mohammadnia, A; Montpetit, A; Nikbakht, H; Papillon-Cavanagh, S; Pastinen, T; Pathania, M; Salomoni, P; Weil, AG; Zeinieh, M | 1 |
| Garimella, MT; Heguy, A; Huse, JT; Judkins, AR; Martinez, D; Santi, M; Sullivan, LM; Thompson, CB; Venneti, S | 1 |
| Allis, CD; Banaszynski, LA; Becher, OJ; Cordero, F; Garcia, BA; Koletsky, MS; Lewis, PW; Lin, S; Muir, TW; Müller, MM | 1 |
| Hatanaka, A; Ishikawa, Y; Issa, JP; Ito, M; Katsushima, K; Kim, SU; Kondo, Y; Natsume, A; Ohka, F; Okano, H; Sato, S; Sekido, Y; Shimogawa, H; Shinjo, K; Takahashi, S; Takeuchi, I; Uesugi, M; Wakabayashi, T | 1 |
| Adamopoulos, C; Dalagiorgou, G; Gargalionis, A; Lea, RW; Papavassiliou, AG; Papavassiliou, KA; Piperi, C; Spyropoulou, A | 1 |
| Cui, X; Nenoi, M; Ninomiya, Y; Sekine-Suzuki, E; Wang, B; Yasuda, T; Yu, D | 1 |
| Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW | 2 |
| Felicella, MM; Judkins, AR; Lewis, PW; Martinez, D; Perry, A; Phillips, JJ; Santi, M; Sullivan, LM; Thompson, CB; Venneti, S; Yarilin, D | 1 |
| Biffoni, M; Cappellari, M; De Maria, R; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Runci, D; Viti, V | 1 |
| Luo, D; Luo, K; Wen, H | 1 |
| Jang, JH; Kim, J; Kim, MS; Kim, YZ; Lee, EH; Lee, SH | 1 |
| Aster, JC; Bernstein, BE; Cahill, DP; Carey, CD; Donohue, LK; Flavahan, WA; Gillespie, SM; Hebert, CH; Liau, BB; Miller, TE; Najm, FJ; Patel, AP; Rich, JN; Rodig, SJ; Shareef, SJ; Sievers, C; Suvà, ML; van Galen, P; Venteicher, AS; Wakimoto, H | 1 |
| Bae, Y; Choi, JS; Han, J; Ko, KS; Lee, S; Rhim, HS | 1 |
| Berger, MS; Lin, C; Lin, CA; Phillips, JJ; Rhodes, CT | 1 |
| Chernov, AV; Remacle, AG; Sounni, NE; Strongin, AY | 1 |
| Hiwasa, T; Iwadate, Y; Koshida, T; Kumazawa, T; Matsutani, T; Sato, K; Shimada, H; Shinmen, N; Takiguchi, M | 1 |
| Balabanov, S; Bokemeyer, C; Braig, M; Hagel, C; Hauber, J; Lamszus, K; Pällmann, N; Preukschas, M; Schulte, A; Sievert, H; Weber, K | 1 |
| Baserga, R; Burgaud, JL; Resnicoff, M | 1 |
2 review(s) available for lysine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Role of Lysine-specific Demethylase 1 and Its Small Molecule Inhibitors in Glioblastoma Multiforme Therapy.
Topics: Flavins; Glioblastoma; Glioma; Histone Demethylases; Histones; Humans; Lysine; Neoplasm Recurrence, Local | 2022 |
The role of histone H3 lysine demethylases in glioblastoma.
Topics: Epigenesis, Genetic; Glioblastoma; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine | 2023 |
31 other study(ies) available for lysine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Cycle Proteins; Complement C9; Glioblastoma; Histones; Humans; Hypoxia; Lysine; Methyltransferases; Poly(ADP-ribose) Polymerases; Tumor Suppressor Proteins | 2022 |
Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Breaks, Double-Stranded; DNA Repair; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Histone Demethylases; Lysine; Mice; Tandem Mass Spectrometry; Temozolomide; Xenograft Model Antitumor Assays | 2023 |
Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell.
Topics: Acetylation; Glioblastoma; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Lysine | 2023 |
Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma.
Topics: ErbB Receptors; Glioblastoma; Humans; Lysine; Methylation; NFATC Transcription Factors; Temozolomide; TNF Receptor-Associated Factor 6; Transcription Factors | 2023 |
Epigenetic Regulation of the Expression of T Cell Stimulatory and Inhibitory Factors by Histone H3 Lysine Modification Enzymes and Its Prognostic Roles in Glioblastoma.
Topics: B7-H1 Antigen; CD28 Antigens; CTLA-4 Antigen; Epigenesis, Genetic; Glioblastoma; Histones; Humans; Lysine; Prognosis; Retrospective Studies; T-Lymphocytes | 2023 |
Starving out brain tumors: a reprogrammed lysine catabolism serves as a novel target for glioblastoma treatment.
Topics: Brain Neoplasms; Glioblastoma; Humans; Lysine | 2023 |
Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to epigenetic deregulation.
Topics: Acetylation; Animals; Apoptosis; Cell Line, Tumor; Cell Self Renewal; Chromatin; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; HEK293 Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Mice; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2020 |
Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma.
Topics: Animals; Antihypertensive Agents; Cell Proliferation; Doxazosin; Drug Delivery Systems; Ephrin-A5; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Lysine; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neural Stem Cells; Neurogenesis; Polycomb Repressive Complex 1; Tumor Cells, Cultured | 2020 |
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B.
Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line; DNA Damage; Drug Resistance, Neoplasm; Etoposide; F-Box Proteins; Glioblastoma; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lomustine; Lysine; Neoplastic Stem Cells; Primary Cell Culture | 2018 |
Histone H3.3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis.
Topics: Bone Neoplasms; Brain Neoplasms; Child; Epigenesis, Genetic; Giant Cell Tumor of Bone; Glioblastoma; HeLa Cells; Histones; Humans; Lysine; Methylation; Mutation | 2018 |
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.
Topics: Autoantigens; Cell Hypoxia; Cell Line; Cell Movement; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Golgi Matrix Proteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Methylation; Response Elements; Transcription, Genetic | 2018 |
SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity.
Topics: Acetylation; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Furans; Gene Knockdown Techniques; Glioblastoma; Humans; Lysine; Mice, Nude; Neoplastic Stem Cells; Quinolines; Sirtuin 2; Tumor Cells, Cultured; Tumor Protein p73; Xenograft Model Antitumor Assays | 2018 |
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Topics: Adolescent; Aged; Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Child; Chromatin; CpG Islands; CRISPR-Cas Systems; DNA Methylation; Epigenesis, Genetic; Female; Gene Editing; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Histone Code; Histones; Humans; Lysine; Male; Methionine; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neurogenesis; Polycomb Repressive Complex 2; Xenograft Model Antitumor Assays | 2019 |
Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.
Topics: Adolescent; Brain Neoplasms; Child; Cohort Studies; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Lysine; Male; Methionine; Mutation; Neuroglia; Polycomb Repressive Complex 2 | 2013 |
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
Topics: Amino Acid Substitution; Animals; Brain Neoplasms; Child; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Glioblastoma; HEK293 Cells; Histones; Humans; Lysine; Methionine; Methylation; Mice; Mutation, Missense; Polycomb Repressive Complex 2; Transgenes | 2013 |
Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma.
Topics: Animals; Apoptosis; Bone Morphogenetic Protein 5; Brain Neoplasms; Cell Differentiation; Cell Line; Chromatin; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Glioblastoma; Heterografts; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neural Stem Cells; Neuronal Plasticity; Polycomb Repressive Complex 2; Transcription Factors; Wnt1 Protein | 2013 |
Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.
Topics: Apoptosis; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Enzyme Induction; Glioblastoma; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Methyltransferases; Neoplasm Grading; Neoplasm Proteins; Protein Methyltransferases; Protein Processing, Post-Translational; Repressor Proteins; RNA Interference; RNA, Small Interfering; Tumor Stem Cell Assay; Up-Regulation | 2014 |
Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells.
Topics: Arsenites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Glioblastoma; Histones; Humans; Lysine; Methylation; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Modulation of uPA, MMPs and their inhibitors by a novel nutrient mixture in human glioblastoma cell lines.
Topics: Arginine; Ascorbic Acid; Brain Neoplasms; Camellia sinensis; Cell Line, Tumor; Copper; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lysine; Manganese; Matrix Metalloproteinases; Micronutrients; Plant Extracts; Proline; Selenium; Tissue Inhibitor of Metalloproteinases; Urokinase-Type Plasminogen Activator | 2014 |
A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Cohort Studies; DNA Mutational Analysis; Female; Glioblastoma; Histones; Humans; Infant, Newborn; Lysine; Male; Methionine; Mutation; Pediatrics; Proportional Hazards Models; Sensitivity and Specificity; Young Adult | 2014 |
(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.
Topics: 2-Aminoadipic Acid; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Cell Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Lysine; Male; Metabolic Networks and Pathways; Mitochondria; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Proton Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted | 2015 |
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
Topics: Animals; Ascorbic Acid; Brain; Brain Neoplasms; Cell Line, Tumor; Dietary Supplements; Glioblastoma; Humans; Lysine; Male; Mice; Mice, Nude; Proline; Tea | 2016 |
Homeobox genes gain trimethylation of histone H3 lysine 4 in glioblastoma tissue.
Topics: Brain Neoplasms; Cadherins; Chromatin Immunoprecipitation; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Glioblastoma; Histones; Humans; Lysine; Methylation; Middle Aged; Promoter Regions, Genetic | 2016 |
Increased expression of the histone H3 lysine 4 methyltransferase MLL4 and the histone H3 lysine 27 demethylase UTX prolonging the overall survival of patients with glioblastoma and a methylated MGMT promoter.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Proliferation; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA-Binding Proteins; Glioblastoma; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methyltransferases; Nuclear Proteins; Prognosis; Retrospective Studies; Tumor Suppressor Proteins | 2017 |
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Topics: Acetylation; Base Sequence; Biomarkers, Tumor; Brain; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatin Assembly and Disassembly; Drug Resistance, Neoplasm; Enhancer Elements, Genetic; Glioblastoma; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Neoplastic Stem Cells; Nuclear Proteins; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Receptors, Notch; Signal Transduction; Transcription, Genetic | 2017 |
Apoptin Gene Delivery by the Functionalized Polyamidoamine Dendrimer Derivatives Induces Cell Death of U87-MG Glioblastoma Cells.
Topics: Apoptosis; Arginine; Brain Neoplasms; Capsid Proteins; Cell Line, Tumor; Cells, Cultured; Dendrimers; DNA; Genetic Therapy; Glioblastoma; Histidine; Humans; Lysine; Transfection | 2017 |
Comparative analyses identify molecular signature of MRI-classified SVZ-associated glioblastoma.
Topics: Brain Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Isocitrate Dehydrogenase; Lateral Ventricles; Lysine; Magnetic Resonance Imaging; Methylation; Mutation; Neoplastic Stem Cells; Neural Stem Cells; Sequence Analysis, RNA | 2017 |
Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Movement; Chromatin; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Fibrosarcoma; Glioblastoma; Histones; Humans; Immunoprecipitation; Lysine; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured | 2009 |
Activation of NFAT signal by p53-K120R mutant.
Topics: Acetylation; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Esophageal Neoplasms; Genes, Reporter; Glioblastoma; Humans; Luciferases; Lysine; Mutagenesis, Site-Directed; NFATC Transcription Factors; Phosphorylation; Point Mutation; Proline Oxidase; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2009 |
Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Dacarbazine; Eukaryotic Translation Initiation Factor 5A; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Guanine; Humans; Lysine; Male; Mixed Function Oxygenases; Molecular Targeted Therapy; Neoplasm Grading; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Temozolomide | 2012 |
Mutant IGF-I receptors as dominant negatives for growth and transformation.
Topics: Analysis of Variance; Animals; Apoptosis; Arginine; Binding Sites; Brain Neoplasms; Cell Division; Cell Line; Glioblastoma; Humans; Lysine; Mutagenesis, Site-Directed; Point Mutation; Rats; Receptor, IGF Type 1; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1995 |