Page last updated: 2024-08-17

lysine and Amyotrophic Lateral Sclerosis

lysine has been researched along with Amyotrophic Lateral Sclerosis in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's10 (40.00)29.6817
2010's6 (24.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Kang, YS; Latif, S1
Buratti, E; Elsässer, SJ; Feederle, R; Garcia Morato, J; Gloeckner, CJ; Hans, F; Kahle, PJ; Neumann, M; Skodras, AA; von Zweydorf, F1
Arenas, A; Barnett, KR; Chen, J; Gal, J; Kasarskis, EJ; Kuang, L; Zhu, H1
Chen, S; Chen, Z; Cui, F; Huang, X; Li, Y; Ling, L; Ren, Y; Sun, B; Yang, F1
Cohen, TJ; Hwang, AW; Lee, VM; Restrepo, CR; Trojanowski, JQ; Yuan, CX1
Ball, LE; Comte-Walters, S; Harlan, BA; Neely, BA; Pehar, M; Sharma, DR; Vargas, MR1
Gourie-Devi, M; Kukreti, R; Ramachandran, S; Taneja, B; Taneja, V; Vats, A; Verma, M1
Kamishina, H; Kato, S; Kobatake, Y; Kohyama, M; Maeda, S; Sakai, H; Sasaki, J; Tsukui, T; Urushitani, M; Yamato, O1
Baas, F; Bourque, PR; Diekstra, FP; Hennekam, EA; Lindhout, D; Ophoff, RA; Schelhaas, HJ; Strengman, E; van den Berg, LH; van Es, MA; Veldink, JH1
Gordon, T; Hegedus, J; Jones, KE1
Ashley, J; Bilgicer, B; Borchelt, DR; Hentz, M; Mowery, RA; Ramirez, AJ; Shaw, BF; Shi, Y; Slunt-Brown, H1
Kikuchi, S; Makita, Z; Ogata, A; Shinpo, K; Takeuchi, M; Tashiro, K; Tsuji, S1
Boehm, BO; Kaufmann, E; Kientsch-Engel, R; Ludolph, AC; Sperfeld, A; Süssmuth, SD; Tumani, H1
Horiuchi, S; Kawaguchi, M; Kobayashi, M; Shibata, N1
Hanemann, CO; Krause, BJ; Ludolph, AC; Meyer, T; Münch, C; Reske, S; Rosenbohm, A; Sedlmeier, R; Sperfeld, AD; Stumm, G; Uttner, I1
Beck, M; Sendtner, M; Toyka, KV1
Gralla, EB; Nishida, CR; Valentine, JS1
Gamonet, F; Lauquin, GJ1
Barnéoud, P; Curet, O1
Asayama, K; Hirano, A; Horiuchi, S; Kato, S; Kobayashi, M; Komori, T; Nagai, R; Shibata, N; Umahara, T1
Asayama, K; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Nakano, I; Nakashima, K; Ohama, E; Saito, M; Shibata, N1
Fujii, J; Kikuchi, S; Moriwaka, F; Ogata, A; Shinpo, K; Taniguchi, N; Tashiro, K1
Asayama, K; Hirano, A; Horiuchi, S; Jono, T; Kato, S; Kobayashi, M; Miyata, S; Nagai, R; Sasaki, S; Shibata, N1
Cleveland, DW; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Liu, J; Nagai, R; Nakano, I; Nakashima, K; Ohama, E; Shibata, N; Takikawa, M1
Bunch, LD; Poser, CM1

Other Studies

25 other study(ies) available for lysine and Amyotrophic Lateral Sclerosis

ArticleYear
Differences of Transport Activity of Arginine and Regulation on Neuronal Nitric Oxide Synthase and Oxidative Stress in Amyotrophic Lateral Sclerosis Model Cell Lines.
    Cells, 2021, 12-16, Volume: 10, Issue:12

    Topics: Amino Acid Transport Systems, Basic; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Line; Gene Expression Regulation; Humans; Hydrogen Peroxide; Lysine; Mice; Motor Neurons; Nitric Oxide Synthase Type I; Oxidative Stress; Spinal Cord; Superoxide Dismutase-1

2021
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
    Nature communications, 2022, 03-09, Volume: 13, Issue:1

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Humans; Lysine; Protein Aggregation, Pathological; Protein Processing, Post-Translational; RNA; Sirtuin 1

2022
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS.
    Human molecular genetics, 2020, 09-29, Volume: 29, Issue:16

    Topics: Acetylation; Adult; Amyotrophic Lateral Sclerosis; beta Karyopherins; Female; Frontotemporal Dementia; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Male; Middle Aged; Nuclear Localization Signals; Protein Domains; RNA-Binding Protein FUS; RNA-Binding Proteins; Sirtuins; Young Adult

2020
A novel D90_K91insN mutation in exon 4 of the SOD1 gene caused familial amyotrophic lateral sclerosis in a Chinese pedigree.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2018, Volume: 19, Issue:7-8

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Asparagine; Computational Biology; DNA Mutational Analysis; Exons; Humans; Lysine; Male; Middle Aged; Models, Molecular; Mutation; Pediatrics; Superoxide Dismutase-1

2018
An acetylation switch controls TDP-43 function and aggregation propensity.
    Nature communications, 2015, Jan-05, Volume: 6

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Frontotemporal Lobar Degeneration; Humans; Immunohistochemistry; Immunoprecipitation; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Oxidative Stress; Protein Aggregation, Pathological; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spinal Cord

2015
Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:2

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Disease Models, Animal; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; Lysine; Mice; Mice, Knockout; Neurons; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Reactive Oxygen Species

2016
Identification of L84F mutation with a novel nucleotide change c.255G > T in the superoxide dismutase gene in a North Indian family with amyotrophic lateral sclerosis.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2016, Volume: 17, Issue:3-4

    Topics: Aged; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Family Health; Female; Genetic Testing; Genotype; Humans; India; Lysine; Male; Middle Aged; Models, Molecular; Phenylalanine; Polymorphism, Single Nucleotide; Superoxide Dismutase-1

2016
Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy.
    Journal of the neurological sciences, 2017, Jan-15, Volume: 372

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies; Calcium-Binding Proteins; Disease Models, Animal; DNA-Binding Proteins; Dogs; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; HEK293 Cells; Humans; Immunoprecipitation; Lysine; Microfilament Proteins; Mutation; Spinal Cord; Superoxide Dismutase-1; Transfection

2017
A case of ALS-FTD in a large FALS pedigree with a K17I ANG mutation.
    Neurology, 2009, Jan-20, Volume: 72, Issue:3

    Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Base Sequence; Dementia; Female; Heterozygote; Humans; Isoleucine; Lysine; Male; Middle Aged; Mutation; Pedigree; Ribonuclease, Pancreatic

2009
Development and use of the incremental twitch subtraction MUNE method in mice.
    Supplements to Clinical neurophysiology, 2009, Volume: 60

    Topics: Action Potentials; Alanine; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Electric Stimulation; Electromyography; Isometric Contraction; Lysine; Male; Mice; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors

2009
Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding.
    Protein science : a publication of the Protein Society, 2012, Volume: 21, Issue:8

    Topics: Acetylation; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Mice; Motion; Mutant Proteins; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Superoxide Dismutase; Superoxide Dismutase-1; Surface-Active Agents

2012
Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cord.
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2002, Volume: 3, Issue:2

    Topics: Aged; Amyotrophic Lateral Sclerosis; Autopsy; Axons; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Neurons; Spinal Cord

2002
The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.
    Neuroscience letters, 2004, Nov-23, Volume: 371, Issue:2-3

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Statistics, Nonparametric

2004
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2005, Volume: 25, Issue:1

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glyoxal; Immunoblotting; Immunohistochemistry; Lysine; Rats

2005
Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.
    Annals of neurology, 2005, Volume: 58, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Arginine; Dementia; DNA Mutational Analysis; Dynactin Complex; Family Health; Female; Humans; Lysine; Magnetic Resonance Imaging; Male; Microtubule-Associated Proteins; Middle Aged; Mutation

2005
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
    Muscle & nerve, 2007, Volume: 36, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Asparagine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Lysine; Middle Aged; Mutation; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1

2007
Characterization of three yeast copper-zinc superoxide dismutase mutants analogous to those coded for in familial amyotrophic lateral sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: Alanine; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Arginine; Edetic Acid; Glycine; Humans; Kinetics; Lysine; Mutagenesis; Paraquat; Point Mutation; Saccharomyces cerevisiae; Spectrophotometry; Superoxide Dismutase

1994
The Saccharomyces cerevisiae LYS7 gene is involved in oxidative stress protection.
    European journal of biochemistry, 1998, Feb-01, Volume: 251, Issue:3

    Topics: Alleles; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Copper; Cytosol; Fungal Proteins; Humans; Isoenzymes; Lysine; Methionine; Mitochondria; Molecular Chaperones; Molecular Sequence Data; Oxidative Stress; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Superoxide Dismutase; Superoxides

1998
Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis.
    Experimental neurology, 1999, Volume: 155, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; Brain; Humans; Lysine; Male; Mice; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Mutation; Postural Balance; Reflex; Salicylates; Solubility; Superoxide Dismutase

1999
Advanced glycation endproducts are deposited in neuronal hyaline inclusions: a study on familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
    Acta neuropathologica, 1999, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Antibodies; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Motor Neurons; Neurofilament Proteins; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins

1999
Astrocytic hyaline inclusions contain advanced glycation endproducts in familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation: immunohistochemical and immunoelectron microscopical analyses.
    Acta neuropathologica, 1999, Volume: 97, Issue:3

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Astrocytes; Cytoplasmic Granules; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lewy Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Mutation; Neurofibrils; Neurons; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins

1999
Detection of an Amadori product, 1-hexitol-lysine, in the anterior horn of the amyotrophic lateral sclerosis and spinobulbar muscular atrophy spinal cord: evidence for early involvement of glycation in motoneuron diseases.
    Acta neuropathologica, 2000, Volume: 99, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Atrophy; Axons; Glycosylation; Humans; Lysine; Muscular Disorders, Atrophic; Neurons; Spinal Cord; Time Factors

2000
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Aged; Aldehydes; Amyotrophic Lateral Sclerosis; Arginine; Deoxyguanosine; Glycosylation; Humans; Imidazoles; Lipid Peroxidation; Lysine; Male; Middle Aged; Motor Neurons; Oxidative Stress; Spinal Cord; Superoxide Dismutase

2000
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Animals; Arginine; Female; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Immunoelectron; Middle Aged; Mutation; Norleucine; Pyrroles; Superoxide Dismutase; Superoxide Dismutase-1

2000
Serum amino acid studies in amyotrophic lateral sclerosis. II. Results of metrecal arginine lysine tolerance tests in US caucasians and Guam Chamorros.
    Archives of neurology, 1966, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Amyotrophic Lateral Sclerosis; Arginine; Blood Chemical Analysis; Chromatography; Humans; Lysine; Male; Middle Aged; Pacific Islands; United States; White People

1966