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lysine and Akinetic-Rigid Variant of Huntington Disease

lysine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bodai, L; Csont, T; Faragó, A; Farkas, A; Neller, A; Siági, F; Szabó, MR; Zsindely, N1
Boulos, A; Ciechanover, A; Cohen-Rosenzweig, C; Hakim-Eshed, V; Kwon, YT; Phuc Nguyen, HH; Riess, O; Yu-Taeger, L; Ziv, NE; Ziv, T1
Bezstarosti, K; Bury, AE; Demmers, JA; Guler, AT; Juenemann, K; Reits, EA; Sap, KA1
Bates, GP; Bodai, L; Finkbeiner, S; Fraenkel, E; Gipson, TA; Housman, DE; Krainc, D; Kratter, IH; Labadorf, A; Lau, A; Marsh, JL; Ng, CW; Ross, CA; Sadri-Vakili, G; Song, W; Thompson, LM; Troncosco, J; Vashishtha, M; Vogel-Ciernia, A; Yildirim, F1
Curtis, MA; Faull, RL; Kim, J; Nicholson, LF; Waldvogel, HJ1
Bajaj, N; Bedford, L; Cavey, JR; Layfield, R; Lowe, J; Mayer, RJ; Paine, S; Sheppard, PW; Thorpe, JR1
Barrow, RK; Mealer, RG; Sixt, KM; Snyder, SH; Subramaniam, S; Usiello, A1
Boo, JH; Han, D; Hwang, YJ; Kim, Y; Kowall, NW; Kwon, OK; Lee, J; Ryu, H; Todorova, K1
Bonner, A; Chen, JM; Cong, X; Czerwieniec, GA; DeGiacomo, F; Ellerby, LM; Gibson, BW; Held, JM; Schilling, B1
Agrawal, N; Cattaneo, E; Illes, K; Lukacsovich, T; Marsh, JL; Pallos, J; Pandolfi, PP; Rockabrand, E; Slepko, N; Steffan, JS; Thompson, LM; Trotman, LC; Zhu, YZ1
Beal, MF; Browne, S; D'Mello, S; Ferrante, RJ; Hewett, S; Kristal, BS; Kubilus, JK; Langley, B; Lee, J; Lu, P; Ratan, RR; Rubinsztein, DC; Ryu, H; Smith, K; Stavrovskaya, IG; Sugars, KL1
Baksi, K; Bhattacharyya, NP; Chattopadhyay, B; Mukhopadhyay, S1
Bates, GP; Becker, CH; Bennett, EJ; Kopito, RR; Ryu, KY; Schulman, H; Shaler, TA; Woodman, B; Zaitseva, TS1
Ahari, SE; Bahar, M; Banoei, MM; Houshmand, M; Kasraie, S; Moin, M; Panahi, MS; Shariati, P1
Blass, JP; Cooper, AJ; Folk, JE; Jeitner, TM; Matson, WR1
Arrieta, A; Bonilla, E; Prasad, AL1

Other Studies

16 other study(ies) available for lysine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Acetylation State of Lysine 14 of Histone H3.3 Affects Mutant Huntingtin Induced Pathogenesis.
    International journal of molecular sciences, 2022, Dec-02, Volume: 23, Issue:23

    Topics: Acetylation; Animals; Drosophila; Histone Acetyltransferases; Histone Deacetylases; Histones; Huntington Disease; Lysine; Protein Processing, Post-Translational

2022
Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 08-04, Volume: 117, Issue:31

    Topics: Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Huntingtin Protein; Huntington Disease; Lysine; Neurons; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Rats; Rats, Transgenic; Ubiquitination

2020
Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains.
    Molecular & cellular proteomics : MCP, 2019, Volume: 18, Issue:9

    Topics: Animals; Brain; Cell Membrane; Huntingtin Protein; Huntington Disease; Lysine; Mice, Mutant Strains; Proteome; Solubility; Ubiquitin; Ubiquitination; Workflow

2019
Targeting H3K4 trimethylation in Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-06, Volume: 110, Issue:32

    Topics: Animals; Animals, Genetically Modified; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Drosophila melanogaster; Female; Gene Expression Profiling; Histone Demethylases; Histones; Humans; Huntingtin Protein; Huntington Disease; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nerve Tissue Proteins; Neurons; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2013
The RAGE receptor and its ligands are highly expressed in astrocytes in a grade-dependant manner in the striatum and subependymal layer in Huntington's disease.
    Journal of neurochemistry, 2015, Volume: 134, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Astrocytes; Corpus Striatum; Ependyma; Female; Formins; Humans; Huntington Disease; Lysine; Male; MAP Kinase Signaling System; Microglia; Middle Aged; Nerve Tissue Proteins; Neurons; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; Severity of Illness Index

2015
Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration.
    Neuroscience letters, 2009, Sep-04, Volume: 460, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Humans; Huntington Disease; Immunohistochemistry; Lewy Bodies; Lysine; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; Polyubiquitin; Proteasome Endopeptidase Complex

2009
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
    The Journal of biological chemistry, 2010, Jul-02, Volume: 285, Issue:27

    Topics: Animals; Corpus Striatum; Cysteine; Glutamine; GTP-Binding Proteins; Humans; Huntington Disease; Lysine; Mice; Mice, Knockout; Mutation; Small Ubiquitin-Related Modifier Proteins; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases

2010
Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease.
    Cell death and differentiation, 2011, Volume: 18, Issue:11

    Topics: Acetylation; Animals; Cell Line; Chromatin Immunoprecipitation; CREB-Binding Protein; Disease Models, Animal; DNA, Ribosomal; Huntington Disease; Lysine; Male; Mice; Mice, Transgenic; Mutation; Pol1 Transcription Initiation Complex Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Transcription, Genetic

2011
Mass spectrometric identification of novel lysine acetylation sites in huntingtin.
    Molecular & cellular proteomics : MCP, 2011, Volume: 10, Issue:10

    Topics: Acetylation; Animals; Antibodies; Brain; Disease Progression; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Huntingtin Protein; Huntington Disease; Lysine; Mass Spectrometry; Mice; Nerve Tissue Proteins; Nuclear Proteins; Protein Processing, Post-Translational; Protein Structure, Tertiary

2011
SUMO modification of Huntingtin and Huntington's disease pathology.
    Science (New York, N.Y.), 2004, Apr-02, Volume: 304, Issue:5667

    Topics: Animals; Animals, Genetically Modified; Cell Line; Cell Nucleus; Corpus Striatum; Cytoplasm; Drosophila; Genes, MDR; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Lysine; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Proline; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; SUMO-1 Protein; Transcription, Genetic; Transfection; Ubiquitin

2004
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-17, Volume: 24, Issue:46

    Topics: Animals; Antibiotics, Antineoplastic; Brain; Cells, Cultured; Gene Silencing; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Lysine; Male; Methylation; Mice; Mice, Transgenic; Mitochondria, Liver; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Plicamycin; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, Glutamate; Transcription, Genetic

2004
Modulation of age at onset of Huntington disease patients by variations in TP53 and human caspase activated DNase (hCAD) genes.
    Neuroscience letters, 2005, Feb-10, Volume: 374, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Arginine; Deoxyribonucleases; Female; Genetic Variation; Genotype; Glucan 1,3-beta-Glucosidase; Humans; Huntington Disease; Lysine; Male; Odds Ratio; Poly-ADP-Ribose Binding Proteins; Polymorphism, Single Nucleotide; Proline; Trinucleotide Repeat Expansion; Tumor Suppressor Protein p53

2005
Global changes to the ubiquitin system in Huntington's disease.
    Nature, 2007, Aug-09, Volume: 448, Issue:7154

    Topics: Animals; Brain; Disease Models, Animal; Humans; Huntington Disease; Inclusion Bodies; Lysine; Mice; Mice, Transgenic; Polyubiquitin; Proteasome Endopeptidase Complex; Ubiquitin

2007
Investigation of tRNA(Leu/Lys) and ATPase 6 genes mutations in Huntington's disease.
    Cellular and molecular neurobiology, 2008, Volume: 28, Issue:7

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; DNA Damage; DNA Mutational Analysis; DNA, Mitochondrial; Genetic Predisposition to Disease; Genetic Testing; Humans; Huntington Disease; Leucine; Lysine; Mitochondrial Diseases; Mutation; RNA, Transfer

2008
Increased levels of gamma-glutamylamines in Huntington disease CSF.
    Journal of neurochemistry, 2008, Volume: 106, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amination; Biogenic Polyamines; Biomarkers; Brain; Female; Glutamine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Neurochemistry; Protein Processing, Post-Translational; Putrescine; Spermidine; Transglutaminases; Up-Regulation

2008
Huntington's disease: studies on brain free amino acids.
    Life sciences, 1988, Volume: 42, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine

1988