Page last updated: 2024-08-17

lysine and Aging

lysine has been researched along with Aging in 414 studies

Research

Studies (414)

TimeframeStudies, this research(%)All Research%
pre-1990115 (27.78)18.7374
1990's93 (22.46)18.2507
2000's97 (23.43)29.6817
2010's82 (19.81)24.3611
2020's27 (6.52)2.80

Authors

AuthorsStudies
Liu, JF; Wu, Y; Yang, JT; Yang, YH1
Baldensperger, T; Dau, T; Di Sanzo, S; Glomb, MA; Heller, R; Henning, C; Kirkpatrick, JM; Leheis, A; Marx, C; Ori, A; Parca, L; Rändler, TL; Spengler, K; Wang, ZQ1
Addicks, GC; Auwerx, J; Green, AE; Kang, BE; Katsyuba, E; Kim, D; Marshall, PL; Menzies, KJ; Patel, S; Renaud, JM; Ryu, D; Vasam, G; Williams, EG; Zhang, H1
Jakhotia, S; Reddy Addi, U; Reddy, GB; Reddy, SS1
Bařinka, C; Meleshin, M; Praetorius, L; Schutkowski, M; Sippl, W; Zessin, M1
Liu, C; Liu, L; Wang, X; Zhao, T1
He, J; Hu, L; Huang, J; Le, M; Li, J; Luo, T; Yuan, Y; Zhang, D; Zheng, L; Zhou, C1
Ding, W; Feng, J; Gao, H; Gao, W; Li, X; Ling, M; Song, Y; Sun, Y; Tang, C; Wang, S; Xing, Y; Yan, R; Yang, X; Yu, N; Zhang, Z1
Aref-Eshghi, E; Bonder, MJ; Choufani, S; Martin-Herranz, DE; Reik, W; Sadikovic, B; Stegle, O; Stubbs, TM; Thornton, JM; Weksberg, R1
Alonso, AP; Cocuron, JC; Cooper, GL; Hoffman, CN; Huseby, CJ; Kuret, J; Thomas, SN; Yang, AJ1
Golian, A; Nikbakhtzade, M; Zarghi, H1
Fritz, KS; Michel, C; Nagaraj, RH; Nahomi, RB; Nandi, SK; Rakete, S1
Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L1
Hedtke, T; Heinz, A; Schmelzer, CEH1
Bernabeu, R; Faillace, MP; Pisera-Fuster, A1
Matsushita, K; Tamura, M; Ukita, M; Yamaguchi, T1
Cai, SQ; Chang, SY; Chen, Z; Cheng, X; Gao, G; Hao, P; Jiang, L; Jiang, Q; Kang, XL; Lin, DY; Liu, XJ; Liu, ZY; Ye, SW; Yin, JA; Yin, SG; Yuan, J1
Dong, Q; He, Q; Li, Y; Lv, C; Ming, X; Wang, H; Yi, Y; Zhang, Z; Zhu, B; Zou, Z1
Binda, C; Edmondson, DE; Iacovino, LG; Manzella, N; Mattevi, A; Mialet-Perez, J; Parini, A; Pisani, L; Resta, J; Rotilio, L; Vanoni, MA1
Alimova, I; Balakrishnan, I; Birks, DK; Carcaboso, AM; Dahl, N; Danis, E; Davidson, N; Donson, A; Foreman, N; Fosmire, S; Gilani, A; Green, A; Gupta, N; Hashizume, R; Hawkins, C; Hulleman, E; Jabado, N; Jones, K; Katagi, H; Lemma, R; Madhavan, K; Meel, MH; Metselaar, DS; Monje, M; Pierce, A; Sanford, B; Serkova, NJ; Sola, I; Steiner, J; Venkataraman, S; Vibhakar, R; Vijmasi, T; Wang, D1
Arakawa, S; Hayashi, H; Ikeda, R; Kayama, T; Kurosaka, D; Marumo, K; Nagai, R; Ohno, RI; Saito, M; Suzuki, R1
Chiba, T; Han, X; Jiang, TX; Lin, K; Luo, ZY; Ma, S; Qiu, XB; Xie, W; Zhu, QQ1
He, Z; Hu, X; Jiang, J; Jiang, N; Li, Q; Liu, C; Liu, L; Wu, Q1
Ikegami, S; Kato, H; Nakamura, Y; Nakano, M; Sakai, N; Suzuki, T; Takahashi, J; Tokida, R; Uehara, M1
Canella, A; Francois, A; Marcho, LM; Stratton, MS1
Dang, W; McCauley, BS1
Lee, AWT; Lee, TL; Liao, J; Luk, ACS; Qi, H; Suen, HC; Yang, L1
Adamski, J; Artati, A; Blaauw, B; Dyar, KA; Huber, S; Möller, G; Tokarz, J; Zeigerer, A1
Fu, X; Hashimoto-Torii, K; Liu, JS; Son, AI; Suto, F; Torii, M1
Brunet, A; Han, S; Hebestreit, K; Mair, WB; Schroeder, EA; Silva-García, CG1
Boyd, RD; DeDecker, AE; Díaz, JAC; Foxcroft, G; Lents, CA; Phillips, CE; Prince, TJ; Stalder, KJ; Vallet, JL1
Ritzenthaler, JD; Roman, J; Zelko, IN; Zhu, J1
Jensen, ON; Kempf, SJ; Rogowska-Wrzesinska, A; Schwämmle, V; Tvardovskiy, A1
Berger, MS; Cardona, AE; Cardona, SM; Huang, SA; Lemmon, VP; Lin, CA; Rhodes, CT; Zunino, G1
Clay Bunn, R; Creecy, A; Nyman, JS; Unal, M; Uppuganti, S; Voziyan, P1
Arnold, P; Bautmans, I; Buyl, R; Gorus, E; Njemini, R; Pool-Goudzwaard, A; Vantieghem, S1
Ito, Y; Muramatsu, N; Nagasawa, T; Sato, T; Yamamoto, Y1
García-Villanova, B; Guerra-Hernández, E; Hougen, HP; Márquez-Ruiz, AB; Rufián-Henares, JÁ; Valenzuela, A1
Saito, M; Satake, Y; Takahashi, K; Takai, S1
Bonini, NM; Kennerdell, JR; Liu, N1
Apaydin, C; Borch Jensen, M; Davis, SS; Ghaemmaghami, S; Gibson, BW; Jasper, H; Juhasz, G; Ramanathan, A; Rodriguez-Fernandez, IA; Schilling, B; Wang, L1
Becker, J; Eickhoff, SB; Mahlke, NS; Reckert, A; Ritz-Timme, S1
Imai, T; Kashiwabara, S; Saito, M; Shiraki, M; Tanaka, S1
Andrade, G; Basso, CG; Cechinel, LR; de Meireles, LCF; de Souza Grefenhagen, ÁI; Galvão, F; Lovatel, GA; Nestler, EJ; Palazzo, RP; Siqueira, IR; Walker, DM1
Karim, L; Sroga, GE; Tang, SY; Vashishth, D1
Michan, S1
He, W; Hu, S; Liu, Z; Ma, G; Xu, H1
Baloh, RH; Bouitbir, J; Dupuis, L; Eschbach, J; Fergani, A; Geny, B; Harms, MB; Larmet, Y; Loeffler, JP; Ludolph, AC; Marion, V; Messadeq, N; René, F; Schlagowski, AI; Shy, ME; Sinniger, J; Weydt, P; Zoll, J1
Ding, X; Duan, P; Hu, G; Lin, YJ; Liu, J; Qiao, Y; Tu, P; Wu, HP; Xu, R1
Arnold, AM; Djousse, L; Hirsch, C; Ix, JH; Kizer, JR; Mukamal, KJ; Newman, AB; Siscovick, D; Thielke, SM; Tracy, RP; Whitson, HE; Yee, LM; Zieman, S1
Amatrudo, JM; Crimins, JL; Hof, PR; Hunt, B; Luebke, JI; Medalla, M; Peters, A; Weaver, CM1
Baron, J; Chen, W; Cheung, CS; Lui, JC1
Asai, K; Hirata, K; Kanazawa, H; Kyoh, S; Tochino, Y1
Bardenheier, A; Bening-Abu-Shach, U; Boxem, M; Broday, L; Ching, K; Chou, TF; Koorman, T; Mishra, P; Podolsky, L; Sapir, A; Sternberg, PW; Tsur, A1
Bhunia, A; Biswas, A; DiMauro, MA; Kar, RK; Nagaraj, RH; Nandi, SK; Raghavan, CT; Wang, B1
Kim, SH; Lee, JH; Park, JY; Park, S1
Chao, PC; Mong, MC; Yin, MC1
Chisholm, NC; Dindot, S; Henderson, ML; Miranda, RC; Park, MJ; Selvamani, A; Sohrabji, F1
Brecht, M; Lenschow, C1
Auger, F; Beuscart, JB; Boulanger, E; Durieux, N; Grossin, N; Jacolot, P; Montaigne, D; Niquet-Leridon, C; Schmidt, AM; Susen, S; Tessier, FJ1
Helfand, SL; Lee, SS; Ni, Z; Pu, M; Wang, M; Wang, X; Wood, JG; Yu, H1
Ferrucci, L; Garcia, M; Harris, TB; Newman, AB; Satterfield, S; Schwartz, AV; Semba, RD; Sun, K; Varadhan, R1
Asghari-Moghadam, M; Bagherzadeh Kasmani, F; Mehri, M1
Larrick, JW; Mendelsohn, AR1
Chun, Y; Kim, CS; Kim, HJ; Kim, J; Park, S; Song, W1
Marumo, K; Saito, M1
Berishvili, E; de Graaff, HJ; Fuijkschot, WW; Houtman, M; Kakabadze, Z; Krijnen, PA; Kupreishvili, K; Meinster, E; Niessen, HW; Schalkwijk, CG; Smulders, YM; van Broekhoven, A; Vonk, AB1
Chang, JH; Cheng, X; Hu, H; Jin, J; Sun, SC; Wang, H; Xiao, Y; Xie, X; Zou, Q1
Gius, D; O'Brien, J; Santa-Maria, CA; Zhu, Y; Zou, X1
Chen, H; Xiao, D; Zheng, X; Zheng, Y1
Gustienė, O; Stanislovaitienė, D; Steponavičiūtė, R; Žaliūnas, R; Žaliūnienė, D; Žemaitienė, R1
Chovatiya, GL; Gupta, S; Khade, B; Ravi, V; Sarate, RM; Waghmare, SK1
Bank, RA; Hooymans, JM; Los, LI; van Deemter, M; Vehof, J1
Dankert, D; Demond, H; Eichenlaub-Ritter, U; Grümmer, R; Heiligentag, M; Horsthemke, B; Trapphoff, T1
Ahmed, T; Baliyan, S; Balschun, D; Dotti, CG; Martin, MG; Martín-Segura, A; Palomer, E; Venero, C1
Bendixen, C; Farajzadeh, L; Kristensen, KK; Larsen, K; Momeni, J1
Dorca, J; Escobar, I; Llatjos, R; Machahua, C; Molina-Molina, M; Montes-Worboys, A; Vicens-Zygmunt, V1
Gruber, J; Hagen, T; Hong, SY; Inoue, T; Ng, LF; Ng, LT; Tolwinski, NS1
Corzo, A; Dozier, WA; Kidd, MT; Schilling, MW1
Babusikova, E; Dobrota, D; Jesenak, M; Kaplan, P; Racay, P1
Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP1
Goto, S; Ishigami, A; Kawakami, K; Nakamura, A; Takahashi, R1
Chalisova, NI; Zakutskii, AN1
Ershler, WB; Ferrucci, L; Guralnik, JM; Longo, DL; Patel, KV; Semba, RD; Sun, K1
Ferrucci, L; Lakatta, EG; Najjar, SS; Semba, RD; Sun, K1
Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Semba, RD; Sun, K1
Gao, WJ; Wang, HX1
Bunch, TD; Fu, XW; Meng, QG; Pei, Y; Suo, L; Yan, CL; Zhu, SE1
Bertholon, C; Chapurlat, R; Gineyts, E; Munoz, F; Sornay-Rendu, E1
Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Guralnik, JM; Semba, RD; Sun, K; Varadhan, R; Walston, J1
Bank, RA; Hooymans, JM; Los, LI; Ponsioen, TL; Snabel, JM; van Deemter, M; van der Worp, RJ1
Brummer, RJ; Heitmann, BL; Nieuwenhuizen, AG; van Vught, AJ; Veldhorst, MA; Westerterp-Plantenga, MS1
Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C1
Branton, SL; Corzo, A; Dozier, WA; Kidd, MT; Tillman, PB1
Bandinelli, S; Ferrucci, L; Guralnik, JM; Semba, RD; Sun, K1
Ferrucci, L; Fink, JC; Semba, RD; Sun, K; Windham, BG1
Fan, X; Giblin, FJ; Liu, X; Monnier, VM; Nemet, I; Qian, J; Strauch, C; Theves, M; Zhang, J1
Tessier, FJ1
Sweatt, JD1
Agis-Balboa, RC; Bahari-Javan, S; Burkhardt, S; Chen, W; Cota, P; Dettenhofer, M; Farinelli, L; Fischer, A; Gogol-Doering, A; Kang, H; Opitz, L; Peleg, S; Salinas-Riester, G; Sananbenesi, F; Wittnam, JL; Zovoilis, A1
Lima, D; Luz, LL; Safronov, BV; Szucs, P1
Goto, S; Kametani, F; Kawakami, K; Nakamoto, H; Nakamura, A1
Mann, M; Walther, DM1
Dai, J; Gomes, AP; Hafner, AV; Palmeira, CM; Rosenzweig, A; Sinclair, DA; Xiao, CY1
Asai, K; Hirata, K; Ichimaru, Y; Kanazawa, H; Kyoh, S; Tochino, Y1
Eguchi, N; Hirohama, J; Jinno, M; Miyazaki, A; Takeuchi, M; Teruya, K; Watanabe, A1
Anderson, HC; Crist, JD; Gardner, BM; Li, Y; Lu, Q; Rodova, M; Wang, J; Woodbury, BG; Yost, JG; Zhong, XB1
Ali, R; Ansari, NA1
Chow, MZ; Krishnan, V; Liu, B; Liu, X; Wang, Z; Zhang, L; Zhou, Z1
Jurvelin, JS; Karjalainen, HM; Kokkonen, HT; Korhonen, RK; Kovanen, V; Kulmala, KA; Mäkelä, J; Rieppo, L; Tiitu, V; Töyräs, J1
Bao, J; Lombard, DB; Tishkoff, DX1
Cauley, JA; Harris, T; Launer, L; Lindquist, K; Rosano, C; Satterfield, S; Schwartz, AV; Simonsick, EM; Vitartas, C; Vittinghoff, E; Yaffe, K1
Aussel, C; Cynober, L; Deutz, NE; Jourdan, M1
Sack, MN1
Begall, S; Dammann, P; Monnier, VM; Sell, DR; Strauch, C1
de Boer, TN; DeGroot, J; Huisman, AM; Lafeber, FP; Mastbergen, SC; Polak, AA; Vos, PA1
Barbanel, G; Billard, JM; Dutar, P; Haxaire, C; Kervern, M; Mothet, JP; Potier, B; Sinet, PM; Turpin, FR1
Bandinelli, S; Ferrucci, L; Guralnik, JM; Patel, KV; Roy, CN; Semba, RD; Sun, K; Varadhan, R1
Goto, M; Iwaki-Egawa, S; Watanabe, Y1
Ikegami, D; Kim, YJ; Niwa, T; Takeshima, H; Ushijima, T; Wakabayashi, M1
Caricilli, AM; Carvalheira, JB; Carvalho, BM; Carvalho-Filho, MA; Cintra, DE; Curi, R; da Silva, AS; De Souza, CT; Guadagnini, D; Hirabara, S; Katashima, CK; Pauli, JR; Ropelle, ER; Saad, MJ; Velloso, LA1
Eda, A; Fukushima, T; Hohjoh, H; Takahashi, M1
Black, MJ; Campbell, DJ; Jenkins, AJ; Kelly, DJ; Kenny, JF; Newcomb, AE; Prior, DL; Schalkwijk, CG; Somaratne, JB; Yii, M1
Bertoldi, K; Cechinel, LR; Elsner, VR; Lovatel, GA; Moysés, F; Muotri, AR; Siqueira, IR; Spindler, C1
Dei, R; Horie, K; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Washimi, Y; Watanabe, M; Yasuda, Y1
Helliger, W; Koutzamani, E; Lindner, HH; Rundquist, I; Sarg, B1
Horiuchi, S; Jono, T; Kimura, T; Kitamura, T; Miyazaki, K; Nagai, R; Takamatsu, J; Yuzuriha, T1
Biemel, KM; Conrad, J; Lederer, MO1
Corzo, A; Hoehler, D; Moran, ET2
Gerrard, JA; Meade, SJ; Miller, AG1
Bakala, H; Borot-Laloi, C; Friguet, B; Hamelin, M1
Luebke, JI; Rosene, DL1
Bakala, H; Bismuth, J; Borot-Laloi, C; Corman, B; Delaval, E; Friguet, B; Hamelin, M1
Anderstam, B; Bárány, P; Fehrman-Ekholm, I; Heimbürger, O; Lindholm, B; Pecoits-Filho, R; Qureshi, AR; Rodríguez Ayala, E; Stenvinkel, P; Suliman, ME1
Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F1
Cutler, RG; Handy, A; Ingram, DK; Lane, MA; Mattison, JA; Monnier, VM; Obrenovich, ME; Roth, GS; Sell, DR1
Frey, J; Meli, M; Perier, C1
ALBANESE, AA; BREITENBACH, J; HIGGONS, RA; ORTO, LA; ZAVATTARO, DN1
FORBES, RM; RAO, T1
KAO, KY; MCGAVACK, TH1
WALIGORA, Z; WENDER, M1
APPELTAUER, GS; BENECH, C; FRANCHI, CM; LEVITAS, A1
DAVIS, JR; HOLLINGER, MA; MORRIS, RN1
Chalisova, NI; Penniiaĭnen, VA1
Zhang, ZW1
Boekelheide, K; Gray, DA; Rasoulpour, RJ; Schoenfeld, HA1
Argirov, OK; Lin, B; Ortwerth, BJ1
Ferket, P; Kogut, J; Kwakkel, R; Veldkamp, T; Verstegen, M1
Bencko, V; Bezdícková, D; Pilin, A; Pudil, F; Sajdok, J; Zídková, J1
Agrawal, CM; Li, X; Shen, X; Wang, X1
Hirao, Y; Kitauchi, T; Ozono, S; Saka, T; Yoneda, T; Yoshida, K; Yoshikawa, M1
Cruz-Sánchez, CZ; Cruz-Sánchez, FF; Gironès, X; Guimerà, A; Kalaria, R; Lafuente, JV; Makita, Z; Ortega, A; Sasaki, N1
Applegate, TJ; Banks, KM; Rush, JK; Thompson, KL1
Kölker, S; Müller, E1
Kil, IS; Lee, JH; Park, JW; Shin, AH1
Bergamini, E; Bonanomi, G; Cavallini, G; Di Stefano, R; Mosca, F; Odetti, P; Parentini, I; Poggi, A; Rossi, S1
Monnier, VM; Obrenovich, ME1
Chang, YM; Killiany, RJ; Luebke, JI; Mangiamele, LA; Rosene, DL1
Amadio, L; Di Pippo, C; Iacobini, C; Menini, S; Oddi, G; Pricci, F; Pugliese, F; Pugliese, G; Ricci, C; Sorcini, M1
Avery, NC; Bailey, AJ1
Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T1
Castellani, RJ; Moreira, PI; Nunomura, A; Perry, G; Smith, MA; Zhu, X1
Schmitt, HP1
Gill, BP1
Degroot, J; Maroudas, A; Roughley, P; Sakkee, N; Sivan, SS; Tsitron, E; van der Ham, F; Wachtel, E1
Asghar, M; Lokhandwala, MF1
Stadtman, ER1
Ahmad, G; Jamil, A; Mushtaq, T; Nisa, MU; Sarwar, M1
Hagino, N; Ishihara, A; Kikuchi, M; Kobayashi, S; Nagai, R; Nishioka, T; Nomura, M1
Ali, AB; Bannister, AP; Thomson, AM1
Cai, W; Ferrucci, L; Goodman, S; Peppa, M; Striker, G; Uribarri, J; Vlassara, H1
Czeslik, E; Friedrich, I; Gursinsky, T; Nass, N; Scheubel, RJ; Schinzel, R; Silber, RE; Simm, A; Wagner, J1
Reinberg, D; Sternglanz, R; Vaquero, A1
Ahmad, G; Mirza, MA; Mushtaq, MM; Mushtaq, T; Nawaz, H; Noreen, U; Sarwar, M1
Carrithers, JA; Haus, JM; Trappe, SW; Trappe, TA1
Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ1
Bencko, V; Bezdícková, D; Pillin, A; Pudil, F1
Liebert, F1
Babušíková, E; Dobrota, D; Jeseňák, M; Kaplán, P; Tribulová, N1
Monnier, VM; Sell, DR; Shen, W; Strauch, CM1
Hilchey, SE; Lerner, J; Smagula, RM1
van den Bosch de Aguilar, P; Vanneste, J1
Robins, SP1
Glimcher, MJ; Strawich, E1
Graf, H; Gruhn, K1
Bartov, I; Bengal, I; Hurwitz, S; Plavnik, I; Talpaz, H1
Cohen, MP; Yu-Wu, V1
Bunn, HF; Chylack, LT; Garlick, RL; Mazer, JS; Tung, WH1
Engel, AG; Rebouche, CJ1
Dobken, J; Siskind, GW; Weksler, ME1
Ausman, LM; Hegsted, DM1
Dwyer, BE; Fando, JL; Wasterlain, CG1
Cerami, A; Monnier, VM1
Leibholz, J; Wilson, RH1
Burgoyne, RD; Gross, J; Rose, SP1
Kumegawa, M; Takuma, T1
Walz, OP1
Hackl, W; Michelchen, G; Otto, E; Poppe, S; Wiesmüller, W1
Cerami, A; Monnier, VM; Stevens, VJ1
McCarthy, JP; Potter, LM; Shelton, JR1
Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R1
Foreman, J; Hwang, SM; Segal, S1
Endo, F; Ishida, S; Kadono, T; Sasaki, T; Yoshinaga, K1
Brahma, KC; Patnaik, BK1
Funaba, M; Hawkins, RL; Inoue, M; Mori, M; Torii, K1
Miesbauer, LR; Schwedler, J; Shun-Shin, GA; Smith, DL; Smith, JB; Sun, Y; Yang, Z; Zhou, X1
Baynes, JW; Bell-Farrow, AD; Cefalu, WT; Fu, MX; Sonntag, WE; Thorpe, SR; Wang, ZQ1
Easter, RA; Kerr, BJ; McKeith, FK1
Baker, DH; Biehl, RR; Hahn, JD1
Baynes, JW; Bichler, J; Reddy, S; Thorpe, SR; Wells-Knecht, KJ1
Bellmunt, MJ; Cosso, L; Odetti, P; Pamplona, R; Portero, M; Prat, J1
Aggoun-Zouaoui, D; Innocenti, GM1
McDonald, R; McGee, C; Reiser, K; Rucker, R1
Boja, B; Monnier, V; Moskowitz, RW; Pokharna, HK1
Reiser, KM1
Höger, H; Lubec, B; Lubec, G; Radner, W; Salzer, H1
Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A1
Carlson, EC; Monnier, VM; Sell, DR1
Monnier, V1
Blackman, MR; Corpas, E; Harman, SM; Roberson, R; Scholfield, D1
Behar, KL; Ogino, T1
Bruce, LL1
Denda, M; Horiuchi, K; Inoue, T; Ishihara, C; Kawana, K; Kushida, K; Takahashi, M1
Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR1
Cutler, RG; Fogarty, JF; Ingram, DK; Johnson, WA; Lane, MA; Masoro, EJ; Mock, OB; Monnier, VM; Reiser, KM; Roth, GS; Sell, DR1
Brumm, MC; Dahlquist, JM; Shelton, DP1
Coffey, RD; Cromwell, GL1
Apgar, GA; Kornegay, ET; Lindemann, MD; Notter, DR1
Carrion, D; Coma, J; Zimmerman, DR1
Dritz, SS; Goodband, RD; Nelssen, JL; Owen, KQ; Tokach, MD1
Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Takahashi, M1
Chagneau, AM; Maaa, N; Peresson, R; Tesseraud, S1
Bailey, AJ; Oxlund, H; Rasmussen, LM; Sims, TJ1
Coffey, MT; Spears, JW; van Heugten, E1
Cosso, L; Marinari, UM; Noberasco, G; Odetti, P; Pronzato, MA; Traverso, N1
Gengin, MT; Shchetinina, NV; Vernigora, AN1
Nerlich, AG; Schleicher, ED; Wagner, E1
Bailey, AJ; Paul, RG1
Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV1
England, JA; Mendes, AA; Saleh, EA; Waldroup, AL; Waldroup, PW; Watkins, SE1
Anthony, NB; Kerr, BJ; Kidd, MT1
Cruz, W; Fogarty, J; Hampel, N; Jiaan, DB; Monnier, VM; Pomerantz, J; Seftel, AD; Zuik, M1
Sell, DR1
Ahmed, MU; Baynes, JW; Brinkmann Frye, E; Degenhardt, TP; Thorpe, SR1
Ducro, BJ; Kwakkel, RP; Verstegen, MW1
Abe, M; Funaba, M; Iriki, T1
Horie, K; Kurokawa, K; Maeda, K; Miyata, T; Sobue, G; Takeda, A; Yasuda, T; Yasuda, Y1
Monnier, VM; Sell, DR2
Douglas, MW; Johnson, ML; Parsons, CM1
Iqbal, M; Klandorf, H; Probert, LL1
Fujii, K; Ishioka, N; Marumo, K; Saito, M1
Bergström, JR; Dritz, SS; Goodband, RD; Nelssen, JL; Nessmith, WB; Richert, BT; Tokach, MD1
Boos, N; Nerlich, AG; Schleicher, ED1
Boeri, D; Maiello, M; Marinari, UM; Odetti, P; Pronzato, MA; Sampietro, L1
Bank, RA; Bayliss, MT; Lafeber, FP; Maroudas, A; Tekoppele, JM1
Higami, Y; Horiuchi, S; Ikeda, T; Iwasaki, M; Shimokawa, I1
Pokharna, HK; Pottenger, LA1
Bailey, AJ; Knott, L1
Sharpe, NA; Tepper, JM1
Aragno, I; Garibaldi, S; Odetti, P; Pronzato, MA; Rolandi, R; Valentini, S1
Baynes, JW; Degenhardt, TP; Frye, EB; Thorpe, SR1
Phillips, FM; Pokharna, HK1
Horiuchi, S; Kimura, T; Miyakawa, T; Miyata, T; Takamatsu, J1
Burnham, DJ; Cantor, AH; Ferguson, NS; Ford, MJ; Gates, RS; Pescatore, AJ; Taraba, JL1
Kanai, M; Nagata, M; Nagayama, Y; Nakamura, K; Saito, N; Takahashi, S; Yoshihara, K1
Akyol, M; Bell, J; Briggs, JD; Dominiczak, MH; Shaw, S1
Baynes, JW; Degenhardt, TP; Thorpe, SR1
Avery, N; Crean, JK; Duance, VC; Eisenstein, SM; Menage, J; Roberts, S; Sims, TJ; Smith, S1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Aotaki-Keen, A; Handa, JT; Hjelmeland, LM; Lutty, GA; Matsunaga, H; Miyata, T; te Koppele, JM; Verzijl, N1
Bass, AH; Knapp, R; Marchaterre, MA1
Alhumadi, NH; Iqbal, M; Klandorf, H; Probert, LL1
Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N1
Bank, RA; Hazleman, BL; Oostingh, G; Riley, GP; TeKoppele, JM1
Bao, M; Li, D; Li, YM; Song, X1
Aotaki-Keen, A; Farboud, B; Handa, JT; Hjelmeland, LM; Miyata, T1
Monnier, VM; Obrenovich, M; Tessier, F1
Requena, JR; Stadtman, ER1
Ben-Ari, Y; Chevassus-Au-Louis, N; Diabira, D; Gozlan, H; Hennou, S1
Baynes, JW; Litchfield, JE; Thorpe, SR1
Aamodt, SM; Colonnese, MT; Constantine-Paton, M; Shi, J; Veras, W1
Nagano, A; Oikawa, M; Takahashi, M1
Lingelbach, LB; McDonald, RB; Mitchell, AE; Rucker, RB1
Brownson, C; Hipkiss, AR1
Hayase, K; Koie, M; Tanaka, M; Yokogoshi, H1
Bank, RA; Bayliss, MT; Baynes, JW; Bijlsma, JW; DeGroot, J; Lafeber, FP; Oldehinkel, E; Tekoppele, JM; Thorpe, SR; Verzijl, N1
Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C1
Brannon, JA; Carlson, CW; Noll, SL; Waibel, PE1
Al-Humadi, NH; Iqbal, M; Kenney, PB; Klandorf, H1
Ferket, PR; Kwakkel, RP; Nixey, C; Noordhuizen, JP; Veldkamp, T1
Buddington, RK; Elnif, J; Malo, C; Sangild, PT1
Fedele, D; Lapolla, A; Traldi, P1
Austic, RE; Park, BC1
Dei, R; Goto, Y; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Watanabe, M; Yamamoto, M; Yasuda, T; Yasuda, Y1
Lu, L; Thompson, JE; Wang, D; Wang, TW1
Stryker, MP; Trachtenberg, JT1
Iqbal, M; Klandorf, H; Rathore, DS; Shi, X; Van Dyke, K1
Brown, TH; McGann, JP; Moyer, JR1
Aniksztejn, L; Ben-Ari, Y; Demarque, M; Morozov, Y; Represa, A1
Donabedian, M; Hare, JM; Rosas, GO; Vandegaer, K; Zieman, SJ1
Bank, RA; Bayliss, MT; Bijlsma, JW; DeGroot, J; Lafeber, FP; Maroudas, A; TeKoppele, JM; Verzijl, N1
Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N; Wenting-Van Wijk, MJ1
Cobden, PM; Cope, DW; Maccaferri, G; Márton, LF; Roberts, JD; Somogyi, P1
Choy, HE; Kim, JH; Nam, KH; Park, SC1
Bank, RA; Baynes, JW; Ben, ZC; Bijlsma, JW; Brau-Benjamin, O; DeGroot, J; Lafeber, FP; Maroudas, A; Mizrahi, J; Schalkwijk, CG; TeKoppele, JM; Thorpe, SR; Verzijl, N1
Bottjer, SW; Iyengar, S1
Arai, K; Chikuda, M; Matsumoto, Y; Takahashi, M1
Faist, V; Heidland, A; Klvanová, J; Krajcoviová-Kudlácková, M; Schinzel, R; Sebeková, K1
Barja, G; Bellmun, MJ; Gredilla, R; Pamplona, R; Portero-Otín, M1
Calvert, CC; Larsen, JA; Rogers, QR1
Borrell, V; del Río, JA; Martínez, A; Solé, M; Soriano, E1
Ali, M; Ruiz-Torres, A1
Campagnoni, AT; Campagnoni, CW; Carey, GD1
Daniels, VG; Murphy, S1
Courtois, Y; Moczar, M; Ouzilou, J; Robert, L1
Allard, R; Bouissou, H; Julian, M; Moczar, M; Ouzilou, J; Pieraggi, MT; Robert, L1
Robert, AM; Robert, L1
Ackley, S; Ho, RW; Lawrence, AE; Mays, LL1
Hwang, SM; Segal, S1
Brickley-Parsons, D; Glimcher, MJ; Shapiro, F1
Weintraub, H1
Deyl, Z; Helm, R; Vancikova, O1
Hoyer, JR; Spiro, RG1
Miyahara, T; Murai, A; Shiozawa, S1
Castellani, I; Giro, MG; Peserico, A; Volpin, D1
Fujii, K; Kuboki, Y; Sasaki, S1
Bernikov, VA; Gorel', FL; Sharypov, VF1
Jin, ZL; Lee, TF; Wang, LC1
Arnal, M; Obled, C1
Chang, YF; Pan, X; Rao, VV1
Katsumaru, H; Murakami, F; Okawa, K; Saito, Y; Shimono, K; Song, WJ1
Grandhee, S; Ibrahim, SA; Miyata, S; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR1
Fujie, M; Horiuchi, K; Inoue, T; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A1
Fogarty, J; Grandhee, SK; Lapolla, A; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR1
Baynes, JW; Dunn, JA; Lyons, TJ; McCance, DR; Thorpe, SR1
Baynes, JW; Dunn, JA; Knecht, KJ; Lyons, TJ; McCance, DR; McFarland, KF; Thorpe, SR1
Deyl, Z; Miksík, I1
Deyl, Z; Miksik, I; Struzinsky, R1
Menzel, EJ; Reihsner, R1
Eyre, DR; Hormel, SE1
Prasad, S; Thakur, MK1
Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M; Sell, DR1
Beardsworth, LJ; Dickson, IR; Eyre, DR1
Baba, S; Hata, F; Igaki, N; Kitamura, Y; Maeda, S; Nishimoto, S; Oimomi, M1
Pensa, M; Rinaldi, E; Simonelli, F1
Baba, S; Nishimoto, S; Oimomi, M1
Arai, K; Iizuka, S; Kinoshita, N; Naito, T; Taniquchi, N; Usui, M1
Ayala, A; Bautista, J; Gordillo, E; Machado, A1
Baynes, JW; Dunn, JA; Patrick, JS; Thorpe, SR1
Baba, S; Hata, F; Hatanaka, H; Kitamura, Y; Maeda, Y; Matsumoto, S; Oimomi, M1
Wilson, RP1
Baba, S; Hatanaka, H; Kitamura, Y; Matsumoto, S; Nishimoto, S; Oimomi, M1
Fabris, N; Mocchegiani, E; Muzzioli, M; Piloni, S1
Olson, AL; Rebouche, CJ1
Bailey, AJ; Barnard, K; Light, ND; Sims, TJ1
Mechanic, GL; Woodley, DT; Yamauchi, M1
Ayala, A; Bautista, J; F-Lobato, M; Gordillo, E; Machado, A1
Kato, H; Naito, H; Nam, TJ; Noguchi, T1
Baba, S; Hata, F; Hatanaka, H; Kitamura, Y; Maeda, Y; Masuta, S; Matsumoto, S; Nakamichi, T; Nishimoto, S; Oimomi, M1
Hata, F; Igaki, N; Kitamura, Y; Maeda, Y; Masuta, S; Matsumoto, S; Nakamichi, T; Nishimoto, S; Oohara, T; Sakai, M1
Ricard-Blum, S; Ville, G1
Auray-Blais, C; Clow, CL; Giguère, R; Goodyer, P; Lemieux, B; Reade, TM; Scriver, CR1
Cree, TC; Schalch, DS1
Bone, AH; Davison, AN; Sabri, MI1
Al-Sarraf, M; Belamaric, J; Cejka, J; Kithier, K; Peterson, WD; Poulik, MD; Vaitkevicius, VK1
Kadar, A; Robert, B; Robert, L1
Liu, LP; Ortwerth, BJ1
Mezei, C; Palmer, FB1
Dunlop, DS; Lajtha, A; Van Elden, W1
Duerre, JA; Lee, CT1
Lovenberg, W; Yamabe, H1
Kim, S; Paik, WK3
Pénzes, L2
Bailey, AJ; Fowler, LJ1
Igo-Kemenes, T; Spadafora, C; Zachau, HG1
Porembska, Z1
Azzola, S; Comolli, R; Ferioli, ME1
Benditt, M; Kim, S; Paik, WK1
Anttinen, H; Kivirikko, KI; Orava, S; Ryhänen, L1
Seyer, JM; Vinson, WC1
Ebel, A; Fontaine, R; Mack, G1
Bornstein, P1
Eichhorn, GL; Miller, J; von Hahn, HP1
Deshmukh, A; Deshmukh, K; Nimni, ME1
Lavinha, F; Lowenthal, A; Mardens, Y; Van Regemorter, N; Van Sande, M1
Bailey, AJ; Robins, SP1
Acharya, PV1
Derouette, S; Moczar, E; Robert, L1
Bowman, R; Sobel, H2
Elsas, LJ; MacDonell, RC; Rosenberg, LE1
Legrand, Y; Pignaud, G1
Graeber, W1
Costello, R; Dubos, R; Schaedler, RW1
Chalkley, R; Panyim, S1
Jackson, DS1
Rohlfing, DL1
Levi, G1
Dixon, GH; Ling, V1
Akazawa, S; Matsuoka, Y; Nakajima, T1
Krishna, I; Levenbook, L1
Spiro, MJ; Spiro, RG1
Albrecht, I; Elsas, LJ; Rosenberg, LE1
Pyhtilä, MJ; Sherman, FG1
Fukushi, S; Spiro, RG1
Segal, S; Smith, I1
Duruy, A1
Fritz, RR; Rappoport, DA; Yamagami, S1
Kodirov, AN; Korot'ko, GF1

Reviews

36 review(s) available for lysine and Aging

ArticleYear
Uncovering Robust Delactoylase and Depyruvoylase Activities of HDAC Isoforms.
    ACS chemical biology, 2022, 06-17, Volume: 17, Issue:6

    Topics: Aging; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Protein Isoforms; Repressor Proteins; Sirtuin 2; Zinc

2022
Unique molecular networks: Formation and role of elastin cross-links.
    IUBMB life, 2020, Volume: 72, Issue:5

    Topics: 2-Aminoadipic Acid; Aging; Animals; Blood Vessels; Connective Tissue Diseases; Elastic Tissue; Elastin; Humans; Ligaments; Lung; Lysine; Microfibrils; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Skin

2020
Protein acetylation in cardiac aging.
    Journal of molecular and cellular cardiology, 2021, Volume: 157

    Topics: Acetylation; Aging; Animals; Biomarkers; Cell Nucleus; Cytoplasm; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation; Heart; Histone Deacetylases; Humans; Lysine; Mitochondria, Heart; Myocardium; Protein Processing, Post-Translational; Sarcomeres

2021
Acetylome regulation by sirtuins in the brain: from normal physiology to aging and pathology.
    Current pharmaceutical design, 2013, Volume: 19, Issue:38

    Topics: Acetylation; Aging; Animals; Autophagy; Brain; Brain Neoplasms; Cellular Senescence; Circadian Rhythm; DNA Damage; Emotions; Humans; Lysine; Neurodegenerative Diseases; Neurogenesis; NF-kappa B; Oxidative Stress; Proteome; Sirtuins

2013
Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.
    Rejuvenation research, 2015, Volume: 18, Issue:4

    Topics: Aging; Animals; Biomarkers; Chromobox Protein Homolog 5; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Stem Cells

2015
[Determinants of bone quality and strength independent of bone remodeling].
    Clinical calcium, 2016, Volume: 26, Issue:1

    Topics: Aging; Animals; Arginine; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Collagen; Diphosphonates; Female; Fractures, Stress; Glucocorticoids; Glycation End Products, Advanced; Humans; Lysine; Male; Osteoporosis; Precision Medicine; Selective Estrogen Receptor Modulators

2016
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.
    Antioxidants & redox signaling, 2016, 08-20, Volume: 25, Issue:6

    Topics: Acetylation; Aging; Biomarkers, Tumor; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Incidence; Longevity; Lysine; Molecular Targeted Therapy; Neoplasm Metastasis; Phenotype; Recurrence; Sirtuin 3; Superoxide Dismutase

2016
The Maillard reaction in the human body. The main discoveries and factors that affect glycation.
    Pathologie-biologie, 2010, Volume: 58, Issue:3

    Topics: Aging; Amino Acids; Diabetes Mellitus; Extracellular Matrix; Food; Free Radicals; Glucose; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Monosaccharides; Oxidation-Reduction; Protein Carbonylation; Proteins; Receptor for Advanced Glycation End Products

2010
Biological significance of protein modifications in aging and calorie restriction.
    Annals of the New York Academy of Sciences, 2010, Volume: 1197

    Topics: Acetylation; Aging; Animals; Caloric Restriction; Histones; Lysine; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proteomics; Rats; Serine

2010
Glycated lysine residues: a marker for non-enzymatic protein glycation in age-related diseases.
    Disease markers, 2011, Volume: 30, Issue:6

    Topics: Aging; Animals; Arthritis; Autoantibodies; Biomarkers; Diabetes Mellitus; Glycoproteins; Glycosylation; Humans; Lysine

2011
Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation.
    Handbook of experimental pharmacology, 2011, Volume: 206

    Topics: Acetylation; Adaptation, Physiological; Aging; Animals; Energy Metabolism; Homeostasis; Humans; Lysine; Mitochondria; Mitochondrial Proteins; Phenotype; Protein Processing, Post-Translational; Sirtuins

2011
The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging.
    Journal of molecular and cellular cardiology, 2012, Volume: 52, Issue:3

    Topics: Acetylation; Adaptation, Physiological; Aging; Animals; Cardiomegaly; Enzyme Activation; Homeostasis; Humans; Lysine; Mitochondria, Heart; Mitochondrial Proteins; Sirtuin 3

2012
Native protein glycoxidation and aging.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:4

    Topics: Aging; Arginine; Carbohydrate Metabolism; Free Radicals; Glucose; Glycation End Products, Advanced; Glycosylation; Half-Life; Humans; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins

2003
[Age-related post-translational modification of proteins in human tissue and its use determination of age in forensic medicine. Review].
    Soudni lekarstvi, 2003, Volume: 48, Issue:4

    Topics: Aging; Arginine; Forensic Medicine; Glycation End Products, Advanced; Humans; Lysine; Protein Processing, Post-Translational

2003
Reduction of lysine intake while avoiding malnutrition--major goals and major problems in dietary treatment of glutaryl-CoA dehydrogenase deficiency.
    Journal of inherited metabolic disease, 2004, Volume: 27, Issue:6

    Topics: Adult; Aging; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Diet, Protein-Restricted; Glutaryl-CoA Dehydrogenase; Humans; Infant; Lysine; Malnutrition; Oxidoreductases Acting on CH-CH Group Donors

2004
Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts.
    Science of aging knowledge environment : SAGE KE, 2005, Jan-26, Volume: 2005, Issue:4

    Topics: Aging; Animals; Apoptosis; Cell Cycle; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Lysine; Maillard Reaction; Models, Biological; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction

2005
Oxidative stress and neurodegeneration.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Aging; Alzheimer Disease; Glycation End Products, Advanced; Humans; Lysine; Nerve Degeneration; Oxidative Stress

2005
Protein oxidation and aging.
    Free radical research, 2006, Volume: 40, Issue:12

    Topics: Aging; Amino Acids; Animals; Cross-Linking Reagents; Humans; Lysine; Methionine; Oxidation-Reduction; Proteins; Reactive Oxygen Species

2006
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs.
    Oncogene, 2007, Aug-13, Volume: 26, Issue:37

    Topics: Acetylation; Aging; Diabetes Mellitus; Histone Deacetylases; Histones; Humans; Lysine; NAD; Neoplasms; Sirtuins

2007
Analysis of the crosslinking components in collagen and elastin.
    Methods of biochemical analysis, 1982, Volume: 28

    Topics: Aging; Amino Acids; Animals; Bone and Bones; Borohydrides; Buffers; Cartilage; Chemical Fractionation; Chemical Phenomena; Chemistry; Chromatography; Collagen; Cyanides; Drug Stability; Elastin; Glycosides; Hexoses; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylysine; Lysine; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Schiff Bases; Skin

1982
Maillard reactions involving proteins and carbohydrates in vivo: relevance to diabetes mellitus and aging.
    Progress in food & nutrition science, 1981, Volume: 5, Issue:1-6

    Topics: Aging; Animals; Blood Proteins; Carbohydrate Metabolism; Collagen; Crystallins; Diabetes Mellitus; Elastin; Glucose; Glycated Hemoglobin; Glycolysis; Hot Temperature; Humans; Lysine; Models, Biological; Proteins

1981
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
    Presse medicale (Paris, France : 1983), 1993, Oct-09, Volume: 22, Issue:30

    Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lysine; Maillard Reaction; Renal Insufficiency

1993
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
New biomarkers of Maillard reaction damage to proteins.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles

1996
Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance.
    Bone, 1998, Volume: 22, Issue:3

    Topics: Aging; Amino Acids; Animals; Bone and Bones; Bone Development; Calcification, Physiologic; Collagen; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteoporosis; Protein-Lysine 6-Oxidase

1998
AGE in micro- and macroangiopathy.
    Contributions to nephrology, 2001, Issue:131

    Topics: Aging; Animals; Arginine; Arteriosclerosis; Cell Adhesion; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Interferon-gamma; Lysine; Membrane Proteins; Microcirculation; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; T-Lymphocytes; Vascular Diseases

2001
Transglutaminase-mediated crosslinking of specific core histone subunits and cellular senescence.
    Annals of the New York Academy of Sciences, 2001, Volume: 928

    Topics: Aging; Animals; Brain; Cell Nucleus; Cells, Cultured; Cellular Senescence; Cross-Linking Reagents; Cytoplasm; Fibroblasts; Glutamine; Histones; Humans; Isoenzymes; Liver; Lysine; Macromolecular Substances; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Phenotype; Protein Subunits; Rats; Rats, Sprague-Dawley; Transglutaminases

2001
Pathophysiology of the intercellular matrix as a whole.
    Advances in experimental medicine and biology, 1977, Volume: 82

    Topics: Aging; Animals; Aorta; Arteriosclerosis; Autoantibodies; Connective Tissue; Elastin; Glucosamine; Glycoproteins; Humans; Lipid Metabolism; Lysine

1977
Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia.
    Diabetes, 1992, Volume: 41 Suppl 2

    Topics: Aging; Arginine; Diabetes Mellitus; Extracellular Matrix Proteins; Humans; Lysine; Maillard Reaction; Proteins; Uremia

1992
Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia.
    Diabetes/metabolism reviews, 1991, Volume: 7, Issue:4

    Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Cross-Linking Reagents; Diabetes Mellitus; Dura Mater; Humans; Lysine; Uremia

1991
Protein and amino acid requirements of fishes.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine

1986
Collagen cross-linking.
    Cellular and molecular biology, 1988, Volume: 34, Issue:6

    Topics: Aging; Animals; Collagen; Connective Tissue; Humans; Lysine; Molecular Structure

1988
The macromolecules of the intercellular matrix of the arterial wall: collagen, elastin, proteoglycans, and glycoproteins.
    Advances in experimental medicine and biology, 1974, Volume: 43, Issue:0

    Topics: Age Factors; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Radioisotopes; Chickens; Collagen; Connective Tissue; Connective Tissue Cells; Elastin; Endothelium; Female; Glycoproteins; Glycosaminoglycans; Humans; Hydroxyproline; Hypertension; In Vitro Techniques; Lysine; Male; Microscopy, Electron; Muscle, Smooth; Proline; Rabbits; Rats; Swine

1974
Current concepts of the crosslinking in bone collagen.
    Clinical orthopaedics and related research, 1972, Volume: 85

    Topics: Aging; Animals; Bone and Bones; Bone Matrix; Borohydrides; Cartilage; Cattle; Chickens; Chromatography, Ion Exchange; Collagen; Decalcification Technique; Hydro-Lyases; Hydroxylysine; Lysine; Radioisotopes; Solubility; Tendons; Tritium; Tropocollagen

1972
Different species of arginase in animal tissues.
    Enzyme, 1973, Volume: 15, Issue:1

    Topics: Aging; Animals; Anura; Arginase; Brain; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Humans; Isoenzymes; Kidney; Kinetics; Liver; Lysine; Molecular Weight; Organ Specificity; Ornithine; Rats; Species Specificity; Submandibular Gland; Sulfhydryl Reagents; Time Factors

1973
The cross-linking of collagen and elastin and its inhibition in osteolathyrism. Is there a relation to the aging process?
    The American journal of medicine, 1970, Volume: 49, Issue:4

    Topics: Aging; Aldehydes; Animals; Bone Diseases; Collagen; Connective Tissue; Elastin; Lathyrism; Lysine; Peptide Biosynthesis; Pyridinium Compounds

1970

Trials

11 trial(s) available for lysine and Aging

ArticleYear
Effect of dietary digestible lysine level on growth performance, blood metabolites and meat quality of broilers 23-38 days of age.
    Journal of animal physiology and animal nutrition, 2020, Volume: 104, Issue:1

    Topics: Aging; Animals; Chickens; Lysine; Male; Meat

2020
Effect of feeding three lysine to energy diets on growth, body composition and age at puberty in replacement gilts.
    Animal reproduction science, 2017, Volume: 184

    Topics: Aging; Animals; Body Composition; Coronavirus Infections; Female; Lysine; Porcine epidemic diarrhea virus; Sexual Maturation; Swine; Swine Diseases

2017
Dietary digestible lysine requirements of male and female broilers from forty-nine to sixty-three days of age.
    Poultry science, 2008, Volume: 87, Issue:7

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Dose-Response Relationship, Drug; Female; Lysine; Male; Nutritional Requirements; Sex Characteristics; Weight Gain

2008
Digestible lysine requirements of male and female broilers from fourteen to twenty-eight days of age.
    Poultry science, 2009, Volume: 88, Issue:8

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Dose-Response Relationship, Drug; Female; Lysine; Male; Nutritional Requirements

2009
Body composition of breeding gilts in response to dietary protein and energy balance from thirty kilograms of body weight to completion of first parity.
    Journal of animal science, 2006, Volume: 84, Issue:7

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Energy Metabolism; Feeding Behavior; Female; Litter Size; Lysine; Parity; Pregnancy; Swine; Weight Gain

2006
The influence of exogenous multienzyme preparation and graded levels of digestible lysine in sunflower meal-based diets on the performance of young broiler chicks two weeks posthatching.
    Poultry science, 2006, Volume: 85, Issue:12

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Helianthus; Lysine; Multienzyme Complexes

2006
Influence of canola meal-based diets supplemented with exogenous enzyme and digestible lysine on performance, digestibility, carcass, and immunity responses of broiler chickens.
    Poultry science, 2007, Volume: 86, Issue:10

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Brassica napus; Chickens; Diet; Digestion; Lysine; Male

2007
Modelling the optimal lysine to threonine ratio in growing chickens depending on age and efficiency of dietary amino acid utilisation.
    British poultry science, 2008, Volume: 49, Issue:1

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Proteins; Lysine; Male; Models, Biological; Nutritional Requirements; Threonine; Weight Gain

2008
Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men.
    Journal of gerontology, 1993, Volume: 48, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Lysine; Male; Middle Aged

1993
The effect of dietary methionine and its relationship to lysine on growth performance of the segregated early-weaned pig.
    Journal of animal science, 1995, Volume: 73, Issue:12

    Topics: Aging; Animals; Cystine; Diet; Lysine; Methionine; Swine; Weaning

1995
Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens.
    Poultry science, 2000, Volume: 79, Issue:9

    Topics: Aging; Animals; Arginine; Biomechanical Phenomena; Chickens; Diet; Elasticity; Female; Food Deprivation; Guanidines; Lysine; Regression Analysis; Tendons; Tensile Strength

2000

Other Studies

367 other study(ies) available for lysine and Aging

ArticleYear
[Proteome and Acetylome Profiling of Livers in C57BL/6J Male Mice during Normal Aging].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2021, Volume: 43, Issue:5

    Topics: Acetylation; Aging; Animals; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Proteome

2021
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
    Nature communications, 2021, 11-18, Volume: 12, Issue:1

    Topics: Aging; Animals; Cell Line; Cell Proliferation; Endothelial Cells; Glycosylation; Glyoxal; Humans; Lysine; Methylation; Mice; Mice, Inbred C57BL; Microtubules; Primary Cell Culture; Protein Processing, Post-Translational; Proteins; Proteomics; Proteostasis; Tubulin

2021
GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression.
    The Journal of cell biology, 2022, 02-07, Volume: 221, Issue:2

    Topics: Acetylation; Aging; Animals; DNA; Dystrophin; Gene Expression Regulation; Humans; Lysine; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Fibers, Skeletal; Muscles; Muscular Atrophy; Muscular Dystrophies; p300-CBP Transcription Factors; Transcriptome; YY1 Transcription Factor

2022
Age-related neuronal damage by advanced glycation end products through altered proteostasis.
    Chemico-biological interactions, 2022, Mar-01, Volume: 355

    Topics: Aging; Animals; Autophagy-Related Protein 5; bcl-2-Associated X Protein; Brain; Brain-Derived Neurotrophic Factor; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Lysine; Neurons; Proteostasis; Pyruvaldehyde; Rats; Rats, Wistar; Ubiquitin; Unfolded Protein Response

2022
Aging-accelerated differential production and aggregation of STAT3 protein in neuronal cells and neural stem cells in the male mouse spinal cord.
    Biogerontology, 2023, Volume: 24, Issue:1

    Topics: Aging; Animals; Lysine; Male; Mice; Neural Stem Cells; Protein Aggregates; Spinal Cord; STAT3 Transcription Factor; Ubiquitins

2023
The emerging role of lysine succinylation in ovarian aging.
    Reproductive biology and endocrinology : RB&E, 2023, Apr-20, Volume: 21, Issue:1

    Topics: Aging; Animals; Female; Follicular Atresia; Humans; Lysine; Mice; Primary Ovarian Insufficiency

2023
Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice.
    Molecular & cellular proteomics : MCP, 2023, Volume: 22, Issue:11

    Topics: Aged; Aging; Animals; Histones; Humans; Infant; Lysine; Mice; Protein Processing, Post-Translational; Proteomics

2023
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.
    Genome biology, 2019, 08-14, Volume: 20, Issue:1

    Topics: Adult; Aging; Biological Clocks; CpG Islands; DNA Methylation; Entropy; Epigenesis, Genetic; Genetic Testing; Genome, Human; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Lysine; Models, Genetic; Sotos Syndrome

2019
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 71, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; tau Proteins

2019
Lysine malonylation and propionylation are prevalent in human lens proteins.
    Experimental eye research, 2020, Volume: 190

    Topics: Aging; Animals; Blotting, Western; Chromatography, Liquid; Crystallins; Cytoskeletal Proteins; Cytosol; Epithelial Cells; Humans; Immunohistochemistry; Lens, Crystalline; Lysine; Malonates; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitochondrial Proteins; Organ Culture Techniques; Paraffin Embedding; Propionates; Sirtuin 3; Sirtuins; Tandem Mass Spectrometry

2020
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
    Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:17

    Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan

2020
Pre-Exposure to Nicotine with Nocturnal Abstinence Induces Epigenetic Changes that Potentiate Nicotine Preference.
    Molecular neurobiology, 2020, Volume: 57, Issue:4

    Topics: Acetylation; Aging; Animals; Behavior, Animal; Brain; Circadian Rhythm; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Lysine; Nicotine; Phenylbutyrates; Phosphorylation; Protein Subunits; Receptors, Nicotinic; Reward; RNA, Messenger; Task Performance and Analysis; Zebrafish

2020
Histone H3K9 methylation is involved in temporomandibular joint osteoarthritis.
    International journal of molecular medicine, 2020, Volume: 45, Issue:2

    Topics: Aging; Animals; Apoptosis; Cell Proliferation; Female; Histones; Lysine; Methylation; Mice; Mice, Inbred C57BL; Osteoarthritis; Temporomandibular Joint

2020
Two conserved epigenetic regulators prevent healthy ageing.
    Nature, 2020, Volume: 579, Issue:7797

    Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cognition; Cognitive Dysfunction; Epigenesis, Genetic; Healthy Aging; Histone-Lysine N-Methyltransferase; Histones; Humans; Longevity; Lysine; Male; Memory; Methylation; Mice; Mitochondria; Neurons; Proteins; RNA Interference; Spatial Learning; Transcription Factors, General

2020
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration.
    Cell research, 2020, Volume: 30, Issue:11

    Topics: Aging; Animals; Carcinogenesis; CCAAT-Enhancer-Binding Proteins; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA Replication; Genome, Human; HeLa Cells; Histones; Humans; Inheritance Patterns; Kinetics; Lysine; Mice; Mitosis; Mouse Embryonic Stem Cells; Nucleosomes; Proliferating Cell Nuclear Antigen; Protein Binding; Protein Domains; Ubiquitin-Protein Ligases

2020
Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging.
    ACS chemical biology, 2020, 07-17, Volume: 15, Issue:7

    Topics: Aging; Animals; Cell Line; Cellular Senescence; Humans; Hydrogen Peroxide; Lysine; Monoamine Oxidase; Mutation; Myoblasts, Cardiac; Myocardium; Protein Engineering; Rats

2020
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
    Cell reports, 2020, 10-20, Volume: 33, Issue:3

    Topics: Aging; Astrocytoma; Brain Stem Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Chromatin; Diffuse Intrinsic Pontine Glioma; Epigenomics; Female; Glioma; Histones; Humans; Lysine; Male; Mutation; Neoplasm Recurrence, Local; Polycomb Repressive Complex 1

2020
Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone.
    Scientific reports, 2020, 11-02, Volume: 10, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Bone and Bones; Bone Diseases; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Mass Spectrometry; Ornithine; Sex Characteristics; Tartrate-Resistant Acid Phosphatase

2020
Proteasome activator PA200 maintains stability of histone marks during transcription and aging.
    Theranostics, 2021, Volume: 11, Issue:3

    Topics: Acetylation; Aging; Animals; Histone Code; Histones; Lysine; Mice; Nuclear Proteins; Proteasome Endopeptidase Complex; Transcription, Genetic

2021
Age-related changes in expression of lysine48 and lysine63 ubiquitin linkages in dopamine neurons of midbrain in mice.
    Neuroreport, 2021, 05-05, Volume: 32, Issue:7

    Topics: Age Factors; Aging; Animals; Dopaminergic Neurons; Lysine; Mesencephalon; Mice; Ubiquitin; Ubiquitination

2021
Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry.
    Scientific reports, 2021, 04-09, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Arginine; Biomarkers; Bone Density; Bone Resorption; Cohort Studies; Female; Femur Neck; Hip; Humans; Japan; Lysine; Male; Middle Aged; Osteoporosis; Reference Values; Registries; Tartrate-Resistant Acid Phosphatase; Vitamin D

2021
Loosening chromatin and dysregulated transcription: a perspective on cryptic transcription during mammalian aging.
    Briefings in functional genomics, 2022, 01-25, Volume: 21, Issue:1

    Topics: Aging; Animals; Chromatin; DNA-Binding Proteins; Histones; Lysine; Mammals; Saccharomyces cerevisiae; Transcription, Genetic

2022
Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation.
    PLoS genetics, 2021, Volume: 17, Issue:7

    Topics: 5-Methylcytosine; Adult Germline Stem Cells; Aging; Alternative Splicing; Animals; Cell Differentiation; Epigenome; Gene Expression Profiling; Gene Expression Regulation; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; RNA, Long Noncoding; Testis

2021
Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging.
    International journal of molecular sciences, 2021, Jul-26, Volume: 22, Issue:15

    Topics: Aging; Animals; Arginine; Lysine; Male; Mice; Muscle, Skeletal; Oxidative Stress; Signal Transduction

2021
Proteome dynamics during postnatal mouse corpus callosum development.
    Scientific reports, 2017, 03-28, Volume: 7

    Topics: Aging; Animals; Animals, Newborn; Cluster Analysis; Corpus Callosum; Isotope Labeling; Lysine; Mass Spectrometry; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Proteome; Receptors, Cell Surface; RNA Interference; RNA, Small Interfering

2017
Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
    Nature, 2017, 04-13, Volume: 544, Issue:7649

    Topics: Aging; Animals; Caenorhabditis elegans; Dietary Fats; Down-Regulation; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Germ Cells; Histone-Lysine N-Methyltransferase; Histones; Intestinal Mucosa; Intestines; Lipid Metabolism; Longevity; Lysine; Methylation; Ribosomal Protein S6 Kinases, 70-kDa; Stearoyl-CoA Desaturase; Up-Regulation

2017
Epigenetic regulation of EC-SOD expression in aging lung fibroblasts: Role of histone acetylation.
    Free radical biology & medicine, 2017, Volume: 112

    Topics: Acetylation; Aging; Animals; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Histone Deacetylase Inhibitors; Histones; Lung; Lysine; Mice; Mice, Inbred C57BL; Primary Cell Culture; Promoter Regions, Genetic; Protein Isoforms; Protein Processing, Post-Translational; Reactive Oxygen Species; Superoxide Dismutase

2017
Accumulation of histone variant H3.3 with age is associated with profound changes in the histone methylation landscape.
    Nucleic acids research, 2017, Sep-19, Volume: 45, Issue:16

    Topics: Aging; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Hepatocytes; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice, Inbred C57BL; Protein Isoforms; Protein Processing, Post-Translational

2017
Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:3

    Topics: Aging; Animals; Cell Differentiation; Cell Movement; Chromatin; Enhancer of Zeste Homolog 2 Protein; Gene Knockout Techniques; Histone-Lysine N-Methyltransferase; Histones; Homologous Recombination; Integrases; Lysine; Methylation; Mice; Neurogenesis; Neurons; Organ Specificity; Recombinant Proteins; S Phase

2018
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
    Bone, 2018, Volume: 110

    Topics: Aging; Animals; Arginine; Bone Density; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Femur; Fractures, Bone; Lysine; Male; Mice; Spectrum Analysis, Raman; X-Ray Microtomography

2018
Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product.
    Experimental gerontology, 2018, 07-15, Volume: 108

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Electromyography; Female; Glycation End Products, Advanced; Humans; Inflammation; Isometric Contraction; Linear Models; Lysine; Male; Muscle Weakness; Muscle, Skeletal; Reaction Time; Sarcopenia; Sex Factors

2018
L-Lysine Attenuates Hepatic Steatosis in Senescence-Accelerated Mouse Prone 8 Mice.
    Journal of nutritional science and vitaminology, 2018, Volume: 64, Issue:3

    Topics: Aging; Alanine Transaminase; Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Cholesterol; Diet; Dietary Supplements; Disease Models, Animal; Liver; Lysine; Male; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Proto-Oncogene Proteins c-akt; Risk Factors; RNA, Messenger; Triglycerides

2018
Differences in non-enzymatic glycation products in human dentine and clavicle: changes with aging.
    International journal of legal medicine, 2018, Volume: 132, Issue:6

    Topics: Adolescent; Adult; Age Determination by Skeleton; Age Determination by Teeth; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Clavicle; Dentin; Female; Forensic Sciences; Humans; Lysine; Male; Middle Aged; Young Adult

2018
Objective Colorimetric Evaluation of Aging-related Articular Cartilage Degeneration.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2018, Volume: 85, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Arginine; Cartilage, Articular; Chromatography, High Pressure Liquid; Color; Colorimetry; Female; Glycation End Products, Advanced; Humans; Hydroxyproline; Lysine; Male; Middle Aged; Osteoarthritis; Prospective Studies

2018
MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging.
    Nature communications, 2018, 10-10, Volume: 9, Issue:1

    Topics: 3' Untranslated Regions; Aging; Animals; Base Sequence; Brain; Drosophila melanogaster; Drosophila Proteins; Gene Expression Profiling; Histones; Lysine; Methylation; MicroRNAs; Models, Biological; Molecular Chaperones; Mutation; Nerve Degeneration; Peptides; Polycomb Repressive Complex 2; Protein Aggregates; Transcriptome

2018
JNK modifies neuronal metabolism to promote proteostasis and longevity.
    Aging cell, 2019, Volume: 18, Issue:3

    Topics: Aging; Animals; Brain; Drosophila; Drosophila Proteins; Gene Ontology; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; JNK Mitogen-Activated Protein Kinases; Longevity; Lysine; Mass Spectrometry; Mutation; Neurons; Pentose Phosphate Pathway; Phosphoprotein Phosphatases; Proteome; Proteostasis; RNA-Seq; Signal Transduction

2019
Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study.
    International journal of legal medicine, 2020, Volume: 134, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; D-Aspartic Acid; Epiglottis; Female; Forensic Medicine; Humans; Infant; Intervertebral Disc; Lysine; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Young Adult

2020
The association of urinary pentosidine levels with the prevalence of osteoporotic fractures in postmenopausal women.
    Journal of bone and mineral metabolism, 2019, Volume: 37, Issue:6

    Topics: Aged; Aging; Arginine; Cohort Studies; Cross-Sectional Studies; Female; Humans; Logistic Models; Lysine; Middle Aged; Multivariate Analysis; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Prevalence

2019
Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications.
    Molecular neurobiology, 2019, Volume: 56, Issue:12

    Topics: Acetylation; Aging; Animals; Avoidance Learning; Chromatin; Epigenesis, Genetic; Hippocampus; Histones; Lysine; Male; Memory; Methylation; Physical Conditioning, Animal; Promoter Regions, Genetic; Rats, Wistar; Survival Rate

2019
Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Collagen; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Specimen Handling; Tibia; Tissue Culture Techniques; Young Adult

2013
The accumulation of the glycoxidation product N(ε)-carboxymethyllysine in cardiac tissues with age, diabetes mellitus and coronary heart disease.
    The Tohoku journal of experimental medicine, 2013, Volume: 230, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Coronary Artery Disease; Diabetes Mellitus; Female; Glycosylation; Humans; Infant; Lysine; Male; Middle Aged; Myocardium; Oxidation-Reduction; Smoking; Young Adult

2013
Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.
    Neurobiology of disease, 2013, Volume: 58

    Topics: Aging; Animals; Cells, Cultured; Cytoplasmic Dyneins; Embryo, Mammalian; Female; Glucagon; Glutamic Acid; Humans; Insulin; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Muscular Atrophy, Spinal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Transfection

2013
Rhein lysinate decreases the generation of β-amyloid in the brain tissues of Alzheimer's disease model mice by inhibiting inflammatory response and oxidative stress.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:7

    Topics: Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Anthraquinones; Brain; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Interleukin-6; Lysine; Male; Malondialdehyde; Mice; Oxidative Stress; Sirtuin 1; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2013
Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2014, Volume: 69, Issue:6

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Biomarkers; Cardiac Rehabilitation; Cardiovascular Diseases; Disabled Persons; Female; Follow-Up Studies; Frail Elderly; Health Status; Humans; Incidence; Lysine; Male; Prevalence; Prognosis; Retrospective Studies; United States

2014
Age-related changes to layer 3 pyramidal cells in the rhesus monkey visual cortex.
    Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:6

    Topics: Aging; Animals; Cognition; Computer Simulation; Dendritic Spines; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Lysine; Macaca mulatta; Male; Membrane Potentials; Microscopy, Electron; Models, Neurological; Neuropsychological Tests; Patch-Clamp Techniques; Pyramidal Cells; Synapses; Visual Cortex

2015
Broad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Cell Cycle; Cell Differentiation; Chromatin Immunoprecipitation; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Ontology; Histones; Kidney; Lung; Lysine; Male; Methylation; Mice, Inbred C57BL; Neurons; Protein Processing, Post-Translational; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Time Factors

2014
Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma.
    Respiratory medicine, 2014, Volume: 108, Issue:5

    Topics: Adult; Aged; Aging; Arginine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Smoking; Sputum; Vital Capacity; Young Adult

2014
Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-16, Volume: 111, Issue:37

    Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cytosol; Humans; Hydroxymethylglutaryl-CoA Synthase; Lysine; Metabolic Networks and Pathways; Mevalonic Acid; Mitochondria; Models, Biological; Mutation; Phenotype; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Maps; Protein Transport; Sumoylation; Ubiquitin

2014
Acetylation of Gly1 and Lys2 promotes aggregation of human γD-crystallin.
    Biochemistry, 2014, Nov-25, Volume: 53, Issue:46

    Topics: Acetylation; Aged; Aging; Amino Acid Sequence; Cataract; gamma-Crystallins; Glycine; Humans; Lysine; Models, Molecular; Protein Aggregates; Protein Unfolding

2014
Plasma levels of lysine, tyrosine, and valine during pregnancy are independent risk factors of insulin resistance and gestational diabetes.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:2

    Topics: Adult; Aging; Asian People; Blood Glucose; Blood Pressure; Diabetes, Gestational; Diet; Energy Intake; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Lysine; Pregnancy; Risk Factors; Tyrosine; Valine

2015
Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice.
    Food & function, 2015, Volume: 6, Issue:2

    Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Caspase 3; Dose-Response Relationship, Drug; Down-Regulation; Galactose; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Peroxidase; Glycation End Products, Advanced; Interleukin-6; Lysine; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Protein Carbonylation; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation

2015
Histone methylation patterns in astrocytes are influenced by age following ischemia.
    Epigenetics, 2015, Volume: 10, Issue:2

    Topics: Acetylation; Acetyltransferases; Aging; Animals; Astrocytes; Brain Ischemia; Cerebral Cortex; Female; Histones; Lysine; Methylation; Methyltransferases; Rats, Sprague-Dawley

2015
Barrel cortex membrane potential dynamics in social touch.
    Neuron, 2015, Feb-18, Volume: 85, Issue:4

    Topics: Afferent Pathways; Aging; Anesthetics; Animals; Animals, Newborn; Female; Interpersonal Relations; Lysine; Male; Membrane Potentials; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Rats; Rats, Wistar; Somatosensory Cortex; Statistics, Nonparametric; Touch; Vibrissae; Wakefulness

2015
Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:5

    Topics: Aging; Animals; Arteries; Dietary Proteins; Endothelium, Vascular; Lysine; Male; Mice; Mice, Inbred C57BL; Pulse Wave Analysis; Receptor for Advanced Glycation End Products; Sirtuin 1; Vascular Cell Adhesion Molecule-1; Vascular Stiffness

2015
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.
    Genes & development, 2015, Apr-01, Volume: 29, Issue:7

    Topics: Aging; Animals; Caenorhabditis elegans; Drosophila melanogaster; Gene Expression Regulation; Histones; Longevity; Lysine; Methylation

2015
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults.
    Journal of hypertension, 2015, Volume: 33, Issue:4

    Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness

2015
Estimation of lysine requirements of growing Japanese quail during the fourth and fifth weeks of age.
    Poultry science, 2015, Volume: 94, Issue:8

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Coturnix; Diet; Dose-Response Relationship, Drug; Lysine; Nutritional Requirements

2015
Treadmill Exercise Attenuates Retinal Oxidative Stress in Naturally-Aged Mice: An Immunohistochemical Study.
    International journal of molecular sciences, 2015, Sep-02, Volume: 16, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Deoxyguanosine; Lysine; Male; Mice; Oxidative Stress; Physical Conditioning, Animal; Retina; Tyrosine

2015
Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature.
    European journal of clinical investigation, 2016, Volume: 46, Issue:4

    Topics: Aging; Animals; Apolipoproteins E; Brain; Coronary Vessels; Endothelium, Vascular; Lysine; Mice, Inbred Strains; Microvessels; Superoxide Dismutase; Survival Rate

2016
Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination.
    The Journal of experimental medicine, 2016, Mar-07, Volume: 213, Issue:3

    Topics: Aging; Amino Acid Sequence; Animals; Autoimmunity; Cell Differentiation; Encephalomyelitis, Autoimmune, Experimental; Endopeptidases; Epitopes; HEK293 Cells; Homeostasis; Humans; Inflammation; Lymphocyte Activation; Lymphopenia; Lysine; Mice, Inbred C57BL; Molecular Sequence Data; Peptides; Protein Binding; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Ubiquitination; ZAP-70 Protein-Tyrosine Kinase

2016
Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.
    Aging cell, 2016, Volume: 15, Issue:3

    Topics: Aging; Animals; DNA Damage; Drosophila melanogaster; Drosophila Proteins; Fat Body; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Lamins; Lysine; Methylation; Models, Biological; Retroelements

2016
N-carboxymethyllysine as a biomarker for coronary artery disease and age-related macular degeneration.
    Medicina (Kaunas, Lithuania), 2016, Volume: 52, Issue:2

    Topics: Aged; Aging; Biomarkers; Body Mass Index; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lipoproteins; Lysine; Macular Degeneration; Male; Middle Aged; Oxidative Stress; Prevalence; Risk Factors

2016
sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:9

    Topics: Aging; Animals; Cell Differentiation; Cell Proliferation; Enzyme Activation; Epidermis; ErbB Receptors; Gene Expression Profiling; Group II Phospholipases A2; Hair Follicle; Histones; Homeostasis; Hyperplasia; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Lysine; Methylation; Mice, Transgenic; Parakeratosis; Proto-Oncogene Proteins c-jun; Sebaceous Glands; Signal Transduction; Stem Cells

2016
FACTORS ASSOCIATED WITH PENTOSIDINE ACCUMULATION IN THE HUMAN VITREOUS.
    Retina (Philadelphia, Pa.), 2017, Volume: 37, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Humans; Lysine; Male; Middle Aged; Pseudophakia; Regression Analysis; Sex Factors; Vitreous Body; Vitreous Detachment; Young Adult

2017
Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Aging; Animals; Chromosomes, Mammalian; Histones; Lysine; Metaphase; Methylation; Mice; Oocytes; Ovulation; RNA-Binding Proteins; RNA, Messenger; Spindle Apparatus

2016
Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons.
    Cell reports, 2016, 09-13, Volume: 16, Issue:11

    Topics: Acetylation; Aging; Animals; Brain-Derived Neurotrophic Factor; Cholesterol; Chromatin; Cognition; Epigenesis, Genetic; Hippocampus; Histones; Long-Term Potentiation; Lysine; Methylation; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcription, Genetic; Voriconazole

2016
A-to-I RNA editing of the IGFBP7 transcript increases during aging in porcine brain tissues.
    Biochemical and biophysical research communications, 2016, Oct-21, Volume: 479, Issue:3

    Topics: Aging; Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Brain Mapping; Cerebellum; Chromosome Mapping; Female; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Lung; Lysine; Methylation; Mice; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sulfates; Swine

2016
Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis.
    Respiratory research, 2016, 11-05, Volume: 17, Issue:1

    Topics: Aged; Aging; Alveolar Epithelial Cells; Antigens, Neoplasm; Arginine; Epithelial Cells; Extracellular Matrix Proteins; Female; Fibroblasts; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Lung; Lysine; Male; Middle Aged; Mitogen-Activated Protein Kinases; Signal Transduction

2016
The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Acylation; Aging; Animals; Caenorhabditis elegans; Drosophila melanogaster; Lysine; Mitochondria; Mitochondrial Proteins; Proteomics; Rats; Sirtuin 3

2016
Oxidative alternations in rat heart homogenate and mitochondria during ageing.
    General physiology and biophysics, 2008, Volume: 27, Issue:2

    Topics: Aging; Anilino Naphthalenesulfonates; Animals; Electron Transport Complex IV; Fluorescent Dyes; Lipid Peroxidation; Lysine; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tryptophan; Tyrosine

2008
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
    Circulation, 2008, Sep-02, Volume: 118, Issue:10

    Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left

2008
Age-related difference of site-specific histone modifications in rat liver.
    Biogerontology, 2009, Volume: 10, Issue:4

    Topics: Acetylation; Age Factors; Aging; Amino Acid Sequence; Animals; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Histones; Liver; Lysine; Male; Methylation; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Serine

2009
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
    Cell biology international, 2008, Volume: 32, Issue:12

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation

2008
Association between serum carboxymethyl-lysine, a dominant advanced glycation end product, and anemia in adults: the Baltimore longitudinal study of aging.
    Journal of the American Geriatrics Society, 2008, Volume: 56, Issue:11

    Topics: Adult; Aging; Anemia; Baltimore; Female; Humans; Longitudinal Studies; Lysine; Male

2008
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults.
    American journal of hypertension, 2009, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aorta; Exercise Test; Female; Follow-Up Studies; Glycation End Products, Advanced; Heart Rate; Humans; Lysine; Male; Middle Aged; Prognosis; Prospective Studies; Reference Values; Risk Factors; Vascular Resistance

2009
Elevated serum advanced glycation end products and poor grip strength in older community-dwelling women.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2009, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Disability Evaluation; Female; Glycation End Products, Advanced; Humans; Lysine; Muscle Strength; Muscle Weakness; Prognosis; Women's Health

2009
Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

    Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Shape; Dendrites; Epigenesis, Genetic; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Interneurons; Lysine; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Staining and Labeling; Synaptic Transmission

2009
Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development.
    Fertility and sterility, 2010, Volume: 93, Issue:3

    Topics: Acetylation; Aging; Animals; Cell Nucleus; Embryonic Development; Female; Fertilization; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Lysine; Male; Meiosis; Mice; Mice, Inbred Strains; Oocytes; Spindle Apparatus; Superovulation; Zygote

2010
Urinary levels of pentosidine and the risk of fracture in postmenopausal women: the OFELY study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone Density; Epidemiologic Methods; Female; Hip Joint; Humans; Lumbar Vertebrae; Lysine; Middle Aged; Osteoporotic Fractures; Postmenopause; Spinal Fractures

2010
Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women.
    Aging clinical and experimental research, 2009, Volume: 21, Issue:2

    Topics: Aged; Aging; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Predictive Value of Tests; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Residence Characteristics; Risk Factors

2009
Pentosidine accumulates in the aging vitreous body: a gender effect.
    Experimental eye research, 2009, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Ciliary Body; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Menopause; Middle Aged; Sex Characteristics; Vitreous Body; Young Adult

2009
Association between dietary protein and change in body composition among children (EYHS).
    Clinical nutrition (Edinburgh, Scotland), 2009, Volume: 28, Issue:6

    Topics: Adolescent; Aging; Algorithms; Arginine; Body Composition; Body Mass Index; Child; Dietary Proteins; Female; Health Surveys; Humans; Lysine; Male; Motor Activity; Obesity; Puberty; Sex Characteristics; Social Class

2009
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:3

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase

2009
Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study.
    European journal of applied physiology, 2010, Volume: 108, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Community Health Planning; Female; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Muscle Strength; Odds Ratio; Walking

2010
Serum carboxymethyl-lysine, a dominant advanced glycation end product, is associated with chronic kidney disease: the Baltimore longitudinal study of aging.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2010, Volume: 20, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Baltimore; Chronic Disease; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney Diseases; Linear Models; Longitudinal Studies; Lysine; Male; Middle Aged; Racial Groups; Smoking

2010
Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.
    The Journal of biological chemistry, 2009, Dec-11, Volume: 284, Issue:50

    Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Cattle; Child; Crystallins; Diabetes Mellitus; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; Lens, Crystalline; Leucine; Lysine; Metals; Mice; Mice, Inbred C57BL; Middle Aged; Molecular Structure; Oxidants; Oxidation-Reduction; Rabbits; Regression Analysis; Young Adult

2009
Neuroscience. Epigenetics and cognitive aging.
    Science (New York, N.Y.), 2010, May-07, Volume: 328, Issue:5979

    Topics: Acetylation; Aging; Animals; Chromatin; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Formins; Gene Expression Regulation; Hippocampus; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Memory; Memory Disorders; Mice; Microfilament Proteins; Nerve Tissue Proteins; Nuclear Proteins; Transcription, Genetic

2010
Altered histone acetylation is associated with age-dependent memory impairment in mice.
    Science (New York, N.Y.), 2010, May-07, Volume: 328, Issue:5979

    Topics: Acetylation; Aging; Animals; Chromatin; Chromatin Assembly and Disassembly; Conditioning, Psychological; Epigenesis, Genetic; Fear; Formins; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Learning; Lysine; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Microfilament Proteins; Nerve Tissue Proteins; Nuclear Proteins; Signal Transduction; Transcription Initiation Site; Transcription, Genetic; Up-Regulation

2010
Local axon collaterals of lamina I projection neurons in the spinal cord of young rats.
    The Journal of comparative neurology, 2010, Jul-15, Volume: 518, Issue:14

    Topics: Aging; Animals; Axons; Image Processing, Computer-Assisted; Lumbar Vertebrae; Lysine; Neural Pathways; Neurons; Photomicrography; Rats; Rats, Wistar; Spinal Cord

2010
Accurate quantification of more than 4000 mouse tissue proteins reveals minimal proteome changes during aging.
    Molecular & cellular proteomics : MCP, 2011, Volume: 10, Issue:2

    Topics: Aging; Animals; Chromatography, Liquid; Disulfides; Frontal Lobe; Hippocampus; Lysine; Mass Spectrometry; Mice; Mice, Inbred C57BL; Proteins; Proteome; Proteomics; Time Factors; Tissue Distribution

2011
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy.
    Aging, 2010, Volume: 2, Issue:12

    Topics: Acetylation; Age Factors; Aging; Amino Acid Sequence; Animals; Cardiomegaly; Cyclophilins; Cyclosporine; Disease Models, Animal; Humans; Lysine; Mice; Mice, 129 Strain; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myocytes, Cardiac; Peptidyl-Prolyl Isomerase F; Protein Conformation; Sirtuin 3; Structure-Activity Relationship; Time Factors

2010
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
    The Journal of allergy and clinical immunology, 2011, Volume: 127, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Asthma; Cross-Linking Reagents; Female; Humans; Lysine; Male; Middle Aged; Respiratory Function Tests; Sputum; Young Adult

2011
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.
    Human reproduction (Oxford, England), 2011, Volume: 26, Issue:3

    Topics: Aging; Arginine; Embryo Implantation; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Glycation End Products, Advanced; Humans; Infertility; Lysine; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies

2011
Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:8

    Topics: Aging; Animals; Base Sequence; Cartilage, Articular; Chondrocytes; Chromatin Immunoprecipitation; Epigenesis, Genetic; Gene Knockdown Techniques; Histone Demethylases; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Molecular Sequence Data; NFATC Transcription Factors; Osteoarthritis; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Up-Regulation

2011
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jul-26, Volume: 108, Issue:30

    Topics: Acetylation; Aging; Aging, Premature; Animals; Cells, Cultured; Cellular Senescence; Chromosomal Proteins, Non-Histone; Disease Models, Animal; DNA Repair; DNA-Binding Proteins; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Lamin Type A; Lysine; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Knockout; Nuclear Matrix; Nuclear Proteins; Protein Precursors; RNA, Small Interfering; Tumor Suppressor p53-Binding Protein 1

2011
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage.
    Osteoarthritis and cartilage, 2011, Volume: 19, Issue:10

    Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Case-Control Studies; Cattle; Collagen; Contrast Media; Hindlimb; Ioxaglic Acid; Lysine; Patella; Tetroses; Tomography, X-Ray Computed

2011
Advanced glycation end product level, diabetes, and accelerated cognitive aging.
    Neurology, 2011, Oct-04, Volume: 77, Issue:14

    Topics: Aged; Aging; Arginine; Chi-Square Distribution; Cognition Disorders; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Longitudinal Studies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests; Odds Ratio

2011
Features, causes and consequences of splanchnic sequestration of amino acid in old rats.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Age Factors; Aging; Amino Acids; Animals; Arginine; Intestinal Mucosa; Kupffer Cells; Liver; Lysine; Protein Biosynthesis; Rats; Viscera

2011
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli).
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2012, Volume: 67, Issue:6

    Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Female; Glycation End Products, Advanced; Longevity; Lysine; Male; Mole Rats; Skin

2012
In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:3

    Topics: Aged; Aging; Arginine; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Collagen; Female; Glycation End Products, Advanced; Humans; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis, Knee; Severity of Illness Index

2012
Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
    Aging cell, 2012, Volume: 11, Issue:2

    Topics: Acetylcysteine; Aging; Animals; Hippocampus; Lysine; Male; Neuronal Plasticity; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine

2012
Circulating selenium and carboxymethyl-lysine, an advanced glycation endproduct, are independent predictors of anemia in older community-dwelling adults.
    Nutrition (Burbank, Los Angeles County, Calif.), 2012, Volume: 28, Issue:7-8

    Topics: Aged; Aged, 80 and over; Aging; Anemia; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Incidence; Italy; Longitudinal Studies; Lysine; Male; Oxidative Stress; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Selenium

2012
Ageing in Werner syndrome.
    Bioscience trends, 2012, Volume: 6, Issue:1

    Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome

2012
Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells.
    Carcinogenesis, 2012, Volume: 33, Issue:12

    Topics: Aging; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Colitis; Colon; Death-Associated Protein Kinases; Dextran Sulfate; Epithelial Cells; Gene Expression; Histones; Intestinal Mucosa; Lysine; Male; Methylation; Mice; Mice, Inbred BALB C; Neoplasms

2012
Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Aging; Animals; Enzyme Inhibitors; Insulin; Insulin Resistance; Lysine; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide Synthase Type II; Nitrosation; Physical Conditioning, Animal; Signal Transduction

2013
Reduction of type IV collagen by upregulated miR-29 in normal elderly mouse and klotho-deficient, senescence-model mouse.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Collagen Type IV; Creatinine; Deoxyguanosine; Gene Expression Profiling; Gene Knockdown Techniques; Gene Silencing; Genes, Reporter; Glucuronidase; HEK293 Cells; Humans; Klotho Proteins; Lysine; Male; Mice; Mice, Inbred ICR; MicroRNAs; Models, Biological; Up-Regulation

2012
Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adult; Aged; Aging; Blood Chemical Analysis; Collagen; Coronary Artery Disease; Diastole; Echocardiography; Glycation End Products, Advanced; Hemodynamics; Humans; Lysine; Male; Middle Aged; Myocardium; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Ventricular Dysfunction, Left

2012
Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study.
    Experimental gerontology, 2013, Volume: 48, Issue:2

    Topics: Age Factors; Aging; Animals; Biomarkers; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Hippocampus; Histones; Lysine; Male; Physical Exertion; Rats; Rats, Wistar

2013
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease.
    Acta neuropathologica, 2002, Volume: 104, Issue:2

    Topics: Adolescent; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Neuroglia; Neurons; Oxidative Stress

2002
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging.
    The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42

    Topics: Aging; Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liquid; Histones; Humans; Lysine; Mass Spectrometry; Metalloendopeptidases; Methylation; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Serine Endopeptidases; Time Factors

2002
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain.
    Pathology international, 2002, Volume: 52, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyramidal Cells

2002
Unexpected carbonyl mobility in aminoketoses: the key to major Maillard crosslinks.
    Angewandte Chemie (International ed. in English), 2002, Mar-01, Volume: 41, Issue:5

    Topics: Aging; Amino Sugars; Arginine; Carbon Radioisotopes; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Radioactive Tracers

2002
Lysine need of heavy broiler males applying the ideal protein concept.
    Poultry science, 2002, Volume: 81, Issue:12

    Topics: Adipose Tissue; Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Glycine max; Lysine; Male; Muscle, Skeletal; Nutritional Requirements; Weight Gain; Zea mays

2002
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics.
    Bioorganic & medicinal chemistry, 2003, Mar-20, Volume: 11, Issue:6

    Topics: Aging; Animals; Catalysis; Cattle; Cross-Linking Reagents; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Guanidines; Indicators and Reagents; Lysine; Maillard Reaction; Methylene Blue; Renin; Ribonuclease, Pancreatic; Somatostatin

2003
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney.
    Archives of biochemistry and biophysics, 2003, Mar-15, Volume: 411, Issue:2

    Topics: Aging; Animals; Antibodies; Antibody Specificity; Basement Membrane; Biomarkers; Collagen; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Oxidative Stress; Proteins; Rats; Rats, Wistar

2003
Aging alters dendritic morphology, input resistance, and inhibitory signaling in dentate granule cells of the rhesus monkey.
    The Journal of comparative neurology, 2003, Jun-09, Volume: 460, Issue:4

    Topics: Action Potentials; Aging; Animals; Behavior, Animal; Cognition; Dendrites; Dentate Gyrus; Female; Lysine; Macaca mulatta; Male; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Receptors, GABA-A; Synaptic Transmission

2003
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.
    European journal of biochemistry, 2003, Volume: 270, Issue:10

    Topics: Adenosine Triphosphate; Aging; Animals; Blotting, Western; Cell Survival; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Lysine; Male; Methylation; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Oxygen; Oxygen Consumption; Peptides; Rats; Rats, Wistar; Stress, Physiological; Time Factors

2003
Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Glomerular Filtration Rate; Humans; Inflammation; Kidney Failure, Chronic; Lysine; Male; Mortality; Nutrition Disorders; Prognosis; Prospective Studies; Renal Dialysis; Survival Analysis

2003
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
    Diabetes, 2003, Volume: 52, Issue:6

    Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Crosses, Genetic; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Islets of Langerhans; Lysine; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvaldehyde

2003
The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2003, Volume: 58, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Arginine; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Collagen; Food Deprivation; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Regression Analysis; Saimiri; Skin

2003
Nutritional and biochemical effects of 19-nortestosterone with lysine supplements in aging convalescents.
    Geriatrics, 1958, Volume: 13, Issue:1

    Topics: Aging; Dietary Supplements; Lysine; Nandrolone; Testosterone

1958
The effect of age on the net requirements for nitrogen, lysine and tryptophan by the well-fed rat.
    Archives of biochemistry and biophysics, 1959, Volume: 82, Issue:2

    Topics: Aging; Animals; Biochemical Phenomena; Lysine; Nitrogen; Purines; Rats; Tryptophan

1959
AGING IN CONNECTIVE TISSUE: A DYNAMIC PROCESS.
    Journal of the American Geriatrics Society, 1963, Volume: 11

    Topics: Aging; Cholesterol; Collagen; Connective Tissue; Hexosamines; Histology; Lipid Metabolism; Lysine; Physiology; Proteins; Rats; Research

1963
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine

1964
UPTAKE OF C-14-L-LYSINE INTO SEGMENTS OF NORMAL RAT SCIATIC NERVE.
    Experimental neurology, 1965, Volume: 12

    Topics: Aging; Carbon Isotopes; Lysine; Metabolism; Rats; Research; Sciatic Nerve

1965
COMPARISON OF TESTICULAR PROTEIN LABELLING IN CRYPTORCHIDISM INDUCED IN PREPUBERTAL AND ADULT RATS.
    Journal of reproduction and fertility, 1965, Volume: 10

    Topics: Adult; Aging; Carbon Isotopes; Cryptorchidism; Histocytochemistry; Humans; Lysine; Male; Proteins; Rats; Research; Testis; Transplantation, Autologous

1965
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:5

    Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen

2003
Lysine needs of summer-reared male broilers from six to eight weeks of age.
    Poultry science, 2003, Volume: 82, Issue:10

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Dietary Proteins; Glycine max; Hot Temperature; Lysine; Male; Mortality; Nutritional Requirements; Seasons; Weight Gain; Zea mays

2003
Maturation of layer V pyramidal neurons in the rat prefrontal cortex: intrinsic properties and synaptic function.
    Journal of neurophysiology, 2004, Volume: 91, Issue:3

    Topics: Action Potentials; Aging; Animals; Dendrites; Electrophysiology; Female; Histocytochemistry; In Vitro Techniques; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses

2004
Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.
    The American journal of pathology, 2003, Volume: 163, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Arginine; Cell Death; Cryptorchidism; Cytoprotection; Gene Expression; Humans; Lysine; Male; Mice; Mice, Transgenic; Mutation; Spermatogenesis; Spermatozoa; Testis; Transgenes; Ubiquitin

2003
2-ammonio-6-(3-oxidopyridinium-1-yl)hexanoate (OP-lysine) is a newly identified advanced glycation end product in cataractous and aged human lenses.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Aged; Aging; Ascorbic Acid; Caproates; Cataract; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glycation End Products, Advanced; Humans; Hydrolysis; Lens, Crystalline; Light; Lysine; Magnetic Resonance Spectroscopy; Middle Aged; Models, Chemical; Pyridinium Compounds; Time Factors; Ultraviolet Rays; Water

2004
Growth responses to dietary lysine at high and low ambient temperature in male turkeys.
    Poultry science, 2003, Volume: 82, Issue:11

    Topics: Aging; Animal Feed; Animals; Diet; Eating; Lysine; Male; Meat; Muscle, Skeletal; Nutritional Requirements; Temperature; Turkeys; Weight Gain

2003
Age-related changes of noncalcified collagen in human cortical bone.
    Annals of biomedical engineering, 2003, Volume: 31, Issue:11

    Topics: Adult; Aged; Aging; Arginine; Bone Remodeling; Cadaver; Collagen; Cross-Linking Reagents; Elasticity; Female; Femoral Fractures; Femur; Haversian System; Humans; Lysine; Male; Middle Aged; Osteogenesis; Osteoporosis; Protein Denaturation

2003
Association between pentosidine and arteriosclerosis in patients receiving hemodialysis.
    Clinical and experimental nephrology, 2004, Volume: 8, Issue:1

    Topics: Aged; Aging; Aorta, Abdominal; Aortic Diseases; Arginine; Arteriosclerosis; Calcinosis; Female; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors; Tomography, X-Ray Computed

2004
N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease.
    Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cytoplasm; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; tau Proteins

2004
Effects of copper source on phosphorus retention in broiler chicks and laying hens.
    Poultry science, 2004, Volume: 83, Issue:6

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Calcification, Physiologic; Chickens; Citrates; Copper; Copper Sulfate; Diet; Dietary Supplements; Lysine; Oviposition; Phosphorus, Dietary; Weight Gain

2004
Glycation-induced inactivation of NADP(+)-dependent isocitrate dehydrogenase: implications for diabetes and aging.
    Free radical biology & medicine, 2004, Dec-01, Volume: 37, Issue:11

    Topics: Aging; Animals; Antioxidants; Cell Line; Cysteine; Diabetes Mellitus; Fructose; Glucose; Glycosylation; Humans; Isocitrate Dehydrogenase; Lysine; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats

2004
Changes in dolichol and pentosidine levels in the age-mismatched heterotopically transplanted rat heart.
    Biogerontology, 2004, Volume: 5, Issue:6

    Topics: Aging; Animals; Arginine; Biological Clocks; Connective Tissue; Dolichols; Heart Transplantation; Lysine; Male; Myocardium; Papillary Muscles; Rats; Rats, Inbred Lew; Transplantation, Heterotopic

2004
Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys.
    Cerebral cortex (New York, N.Y. : 1991), 2005, Volume: 15, Issue:4

    Topics: Action Potentials; Aging; Animals; Behavior, Animal; Cognition; Electrophysiology; Learning; Lysine; Macaca mulatta; Membrane Potentials; Memory; Memory, Short-Term; Patch-Clamp Techniques; Prefrontal Cortex; Psychomotor Performance; Pyramidal Cells; Recognition, Psychology

2005
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:3

    Topics: Age Factors; Aging; Aldehydes; Animals; Body Weight; Dinoprost; Extracellular Matrix; Galectin 3; Glomerulonephritis; Glycation End Products, Advanced; Kidney Glomerulus; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Enzymic and non-enzymic cross-linking mechanisms in relation to turnover of collagen: relevance to aging and exercise.
    Scandinavian journal of medicine & science in sports, 2005, Volume: 15, Issue:4

    Topics: Aging; Bone and Bones; Collagen; Connective Tissue; Exercise; Glucose; Glycation End Products, Advanced; Humans; Hydroxylation; Lysine; Maillard Reaction; Oxidation-Reduction; Physical Exertion; United Kingdom

2005
Immunohistochemical localization of advanced glycation end products in pinguecula.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles

2006
epsilon-Glycation, APP and Abeta in ageing and Alzheimer disease: a hypothesis.
    Medical hypotheses, 2006, Volume: 66, Issue:5

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Glycation End Products, Advanced; Humans; Lysine; Models, Neurological

2006
Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs.
    The Biochemical journal, 2006, Oct-01, Volume: 399, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Chondroitin Sulfate Proteoglycans; Collagen; Discitis; Extracellular Matrix Proteins; Humans; Intervertebral Disc; Lectins, C-Type; Lysine; Middle Aged; Proteoglycans

2006
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:5

    Topics: Age Factors; Aging; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Cyclic N-Oxides; Dietary Supplements; Homeostasis; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Lysine; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Inbred F344; Spin Labels; Triglycerides

2006
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of aged rat.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: Age Factors; Aging; Animals; Antibodies; Capillaries; Choroid; Choroidal Neovascularization; Glycation End Products, Advanced; Lysine; Macular Degeneration; Male; Organ Culture Techniques; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2007
Robust correlations between action potential duration and the properties of synaptic connections in layer 4 interneurones in neocortical slices from juvenile rats and adult rat and cat.
    The Journal of physiology, 2007, Apr-01, Volume: 580, Issue:Pt 1

    Topics: Action Potentials; Aging; Animals; Cats; Data Interpretation, Statistical; Electrophysiology; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Lysine; Male; Neocortex; Neural Pathways; Rats; Rats, Sprague-Dawley; Synapses; Visual Cortex

2007
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Diet; Dinoprost; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lysine; Male; Middle Aged; Oxidative Stress; Pyruvaldehyde

2007
Advanced glycation endproducts: a biomarker for age as an outcome predictor after cardiac surgery?
    Experimental gerontology, 2007, Volume: 42, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Coronary Artery Bypass; Glycation End Products, Advanced; Heart; Humans; Lysine; Middle Aged; Pericardial Effusion; Predictive Value of Tests; Treatment Outcome

2007
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 103, Issue:6

    Topics: Actins; Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Muscle Contraction; Muscle Strength; Muscular Diseases; Myofibrils; Myosins; Quadriceps Muscle

2007
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2007
Contents of pentosidine in the tissue of the intervertebral disc as an indicator of the human age.
    Soudni lekarstvi, 2007, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Age Determination by Skeleton; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Humans; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged

2007
Age-dependent effect of oxidative stress on cardiac sarcoplasmic reticulum vesicles.
    Physiological research, 2008, Volume: 57 Suppl 2

    Topics: Age Factors; Aging; Animals; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Lipid Peroxidation; Lysine; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sarcoplasmic Reticulum; Subcellular Fractions; Thiobarbituric Acid Reactive Substances; Tryptophan

2008
Aging, diabetes, and renal failure catalyze the oxidation of lysyl residues to 2-aminoadipic acid in human skin collagen: evidence for metal-catalyzed oxidation mediated by alpha-dicarbonyls.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aging; Child; Child, Preschool; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Humans; Infant; Infant, Newborn; Lysine; Middle Aged; Oxidation-Reduction; Skin; Skin Aging

2008
Developmental changes in amino acid transport in the chicken erythrocyte.
    Comparative biochemistry and physiology. A, Comparative physiology, 1983, Volume: 74, Issue:4

    Topics: Aging; Amino Acids; Animals; Chickens; Erythrocytes; Glycine; Kinetics; Leucine; Lysine

1983
Ageing of the spinal ganglion neurons in the rat: a radioautographic study following injection of [3H]lysine.
    Neuroscience letters, 1980, Volume: 18, Issue:3

    Topics: Aging; Animals; Autoradiography; Axonal Transport; Ganglia, Spinal; Lysine; Male; Neurons; Rats; Rats, Inbred Strains; Tritium

1980
Differences in the extent and heterogeneity of lysyl hydroxylation in embryonic chick cranial and long bone collagens.
    The Journal of biological chemistry, 1983, Jan-10, Volume: 258, Issue:1

    Topics: Aging; Animals; Bone and Bones; Bone Development; Chick Embryo; Chickens; Collagen; Hydroxylysine; Lathyrism; Lysine; Skull

1983
[Supplementation of the amino acid composition of protein-rich wheat with protein concentrates and L-lysine in rations for laying hens. 4. Effect of various rearing diets on crude protein, fat and ash contents of the utilizable and nonutilizable parts of
    Die Nahrung, 1983, Volume: 27, Issue:6

    Topics: Aging; Animals; Body Composition; Body Weight; Chickens; Diet; Dietary Fats; Dietary Proteins; Female; Lysine; Minerals; Oviposition

1983
The amino acid requirements of growing turkeys. 2. Experimental validation of model-calculated requirements for sulfur amino acids and lysine.
    Poultry science, 1983, Volume: 62, Issue:12

    Topics: Aging; Amino Acids, Sulfur; Animals; Body Weight; Diet; Lysine; Male; Models, Biological; Nutritional Requirements; Turkeys

1983
Age-related changes in non-enzymatic glycosylation of human basement membranes.
    Experimental gerontology, 1983, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Basement Membrane; Diabetes Mellitus; Female; Humans; Kidney Glomerulus; Lens Capsule, Crystalline; Lysine; Male; Membrane Proteins; Middle Aged

1983
Nonenzymatic glycation of human lens crystallin. Effect of aging and diabetes mellitus.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Crystallins; Diabetes Mellitus; Female; Glucose; Humans; Infant; Lens, Crystalline; Lysine; Male; Middle Aged; Solubility

1984
Tissue distribution of carnitine biosynthetic enzymes in man.
    Biochimica et biophysica acta, 1980, Jun-05, Volume: 630, Issue:1

    Topics: Adolescent; Adult; Aging; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Aldehyde-Lyases; Carnitine; Child; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Glucuronates; Humans; Infant; Kinetics; Lactones; Lysine; Male; Middle Aged; Mixed Function Oxygenases; Organ Specificity; Tissue Distribution

1980
Effect of age on ease of B-cell tolerance induction.
    Cellular immunology, 1980, Sep-15, Volume: 55, Issue:1

    Topics: Aging; Animals; Antibody Affinity; B-Lymphocytes; Dinitrobenzenes; Glutamates; Immune Tolerance; Lysine; Male; Mice; Mice, Inbred BALB C

1980
Protein requirements of adult cebus monkeys (Cebus albifrons).
    The American journal of clinical nutrition, 1980, Volume: 33, Issue:12

    Topics: Aging; Amino Acids; Animals; Body Weight; Cebidae; Cebus; Cholesterol; Dietary Proteins; Female; Food Analysis; Lactalbumin; Lysine; Male; Nutritional Requirements

1980
Rat brain protein synthesis declines during postdevelopmental aging.
    Journal of neurochemistry, 1980, Volume: 35, Issue:3

    Topics: Aging; Animals; Brain; Female; Lysine; Nerve Tissue Proteins; Rats

1980
Nonenzymatic browning in vivo: possible process for aging of long-lived proteins.
    Science (New York, N.Y.), 1981, Jan-30, Volume: 211, Issue:4481

    Topics: Aging; Animals; Cattle; Chemical Phenomena; Chemistry; Crystallins; Diabetes Mellitus; Glucose; Glucosephosphates; In Vitro Techniques; Lysine; Proteins; Spectrophotometry, Ultraviolet

1981
Digestion in the pigs between 7 and 35 d of age. 4. The digestion of amino acids in pigs given milk and soya-bean proteins.
    The British journal of nutrition, 1981, Volume: 45, Issue:2

    Topics: Aging; Amino Acids; Animals; Dietary Proteins; Digestion; Glycine max; Ileum; Intestine, Small; Lysine; Methionine; Milk Proteins; Plant Proteins; Swine

1981
Influence of prenatal hypoxia on brain development: effects on body weight, brain weight, DNA, protein, acetylcholinesterase, 3-quinuclidinyl benzilate binding, and in vivo incorporation of [14C]lysine into subcellular fractions.
    Journal of neurochemistry, 1981, Volume: 37, Issue:1

    Topics: Acetylcholinesterase; Aging; Animals; Body Weight; Brain; DNA; Female; Fetal Diseases; Fetus; Hypoxia; Lysine; Nerve Tissue Proteins; Organ Size; Pregnancy; Quinuclidines; Quinuclidinyl Benzilate; Rats; Subcellular Fractions

1981
Postnatal development of trypsin-like esteroproteases in mouse submandibular gland.
    Histochemistry, 1981, Volume: 72, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Female; Histocytochemistry; Isoenzymes; Lysine; Male; Mice; Mice, Inbred Strains; Sex Factors; Submandibular Gland; Trypsin

1981
[Effect of a frequent administration of a daily lysine supplement on the utilization of nutrients in pigs from 20 to 100 kg body weight. 1. Description of methods, growth and food utilization].
    Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde, 1981, Volume: 46, Issue:3

    Topics: Aging; Animals; Body Weight; Lysine; Nutritional Physiological Phenomena; Swine

1981
[Lysine requirement of fattening boars with reference to their performance. 4. Selected quantitative characteristics of the carcass and derivation of the lysine requirement].
    Archiv fur Tierernahrung, 1981, Volume: 31, Issue:7-8

    Topics: Adipose Tissue; Aging; Animals; Digestion; Energy Metabolism; Lysine; Male; Nutritional Requirements; Swine

1981
Lysine and protein requirements of growing turkeys.
    Poultry science, 1981, Volume: 60, Issue:12

    Topics: Aging; Animals; Body Weight; Dietary Proteins; Female; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Turkeys

1981
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
    The Tohoku journal of experimental medicine, 1982, Volume: 137, Issue:1

    Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine

1982
Developmental pattern of cystine transport in isolated rat renal tubules.
    Biochimica et biophysica acta, 1982, Aug-25, Volume: 690, Issue:1

    Topics: Aging; Animals; Biological Transport; Cystine; Female; Kidney Cortex; Kidney Tubules; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains

1982
Induction of immunological tolerance to single-stranded and double-stranded DNA.
    Scandinavian journal of immunology, 1982, Volume: 16, Issue:3

    Topics: Aging; Animals; Antibody-Producing Cells; Antigens; Autoantibodies; DNA; DNA, Single-Stranded; Female; Glutamates; Hemolytic Plaque Technique; Immune Tolerance; Lysine; Mice; Mice, Inbred C3H; Mice, Inbred NZB

1982
Changes in the characteristics of collagen of young male garden lizards following centrophenoxine and lysine treatment.
    Experimental gerontology, 1982, Volume: 17, Issue:5

    Topics: Aging; Animals; Bone and Bones; Collagen; Glycolates; Lizards; Lysine; Male; Meclofenoxate; Skin; Tendons

1982
Effect of continuous infusion of lysine via different routes and hepatic vagotomy on dietary choice in rats.
    Physiology & behavior, 1995, Volume: 58, Issue:2

    Topics: Aging; Animals; Diet; Eating; Food Preferences; Infusions, Parenteral; Injections, Intraventricular; Liver; Lysine; Male; Rats; Rats, Sprague-Dawley; Vagotomy

1995
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
    Journal of protein chemistry, 1995, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Carbamates; Crystallins; Female; Glutathione; Guanidine; Guanidines; Humans; Lysine; Male; Middle Aged; Renal Insufficiency; Solubility; Spectrometry, Mass, Fast Atom Bombardment; Water

1995
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:6

    Topics: Aging; Animals; Arginine; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Energy Intake; Female; Food Deprivation; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rats; Rats, Inbred BN; Skin

1995
Effect on performance and carcass characteristics of nursery to finisher pigs fed reduced crude protein, amino acid-supplemented diets.
    Journal of animal science, 1995, Volume: 73, Issue:2

    Topics: Aging; Amino Acids; Animals; Body Composition; Body Weight; Diet; Dietary Proteins; Female; Food, Fortified; Kidney; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Swine; Threonine; Trypsin

1995
Ideal digestible lysine level for early- and late-finishing swine.
    Journal of animal science, 1995, Volume: 73, Issue:3

    Topics: Aging; Amino Acids; Animal Feed; Animals; Blood Urea Nitrogen; Body Composition; Female; Food, Fortified; Glycine max; Lysine; Male; Nutritional Requirements; Random Allocation; Sex Characteristics; Swine; Weight Gain; Zea mays

1995
N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins.
    Biochemistry, 1995, Aug-29, Volume: 34, Issue:34

    Topics: Aging; Antigens; Chromatography, Gel; Crystallins; Enzyme-Linked Immunosorbent Assay; Fructose; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Kinetics; Lysine; Maillard Reaction; Serum Albumin, Bovine

1995
Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age.
    Biochimica et biophysica acta, 1995, Aug-15, Volume: 1272, Issue:1

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Extracellular Matrix; Hydroxyproline; Lung; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Solubility; Spectrometry, Fluorescence

1995
Juvenile visual callosal axons in kittens display origin- and fate-related morphology and distribution of arbors.
    The European journal of neuroscience, 1994, Dec-01, Volume: 6, Issue:12

    Topics: Aging; Animals; Axons; Cats; Cerebral Cortex; Corpus Callosum; Image Processing, Computer-Assisted; Lysine; Neural Pathways

1994
Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50A, Issue:1

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Dipeptides; Energy Intake; Granulation Tissue; Lysine; Male; Rats; Rats, Inbred F344; Time Factors; Wound Healing

1995
Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1995, Volume: 13, Issue:1

    Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Collagen; Female; Lysine; Maillard Reaction; Osteoarthritis; Peptide Mapping; Protein-Lysine 6-Oxidase; Rabbits; Solubility

1995
Influence of age and long-term dietary restriction on enzymatically mediated crosslinks and nonenzymatic glycation of collagen in mice.
    Journal of gerontology, 1994, Volume: 49, Issue:2

    Topics: Aging; Animals; Aorta; Arginine; Collagen; Cross-Linking Reagents; Food Deprivation; Glycosylation; Lung; Lysine; Male; Mice; Mice, Inbred C57BL; Skin; Spectrometry, Fluorescence; Tendons

1994
L-arginine reduces kidney collagen accumulation and N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse.
    Journal of gerontology, 1994, Volume: 49, Issue:2

    Topics: Aging; Animals; Arginine; Basement Membrane; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Hydroxyproline; Kidney; Kidney Glomerulus; Lysine; Mice

1994
Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Bone Diseases; Cartilage, Articular; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Linking Reagents; Female; Femur Head Necrosis; Hip Joint; Humans; Joint Diseases; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Osteoporosis

1994
Differential effects of type 2 (non-insulin-dependent) diabetes mellitus on pentosidine formation in skin and glomerular basement membrane.
    Diabetologia, 1993, Volume: 36, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Basement Membrane; Biomarkers; Child; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Infant; Kidney Glomerulus; Lysine; Male; Middle Aged; Skin; Skin Aging

1993
Characterization of macromolecule resonances in the 1H NMR spectrum of rat brain.
    Magnetic resonance in medicine, 1993, Volume: 30, Issue:1

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain Chemistry; Chromatography, Gel; Cytosol; Female; Hydrogen; Image Enhancement; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Methionine; Myelin Sheath; Proteins; Rats; Rats, Sprague-Dawley

1993
Postnatal development and specification of the cat's visual corticotectal projection: efferents from the posteromedial lateral suprasylvian area.
    Brain research. Developmental brain research, 1993, May-21, Volume: 73, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Axons; Cats; Cerebral Aqueduct; Efferent Pathways; Lysine; Neurons; Superior Colliculi; Synaptic Transmission; Thalamus; Visual Cortex

1993
Quantification of the cross-link pentosidine in serum from normal and uremic subjects.
    Clinical chemistry, 1993, Volume: 39, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Uremia

1993
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Diabetes Mellitus, Type 1; Female; Glycosylation; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1993
Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jan-09, Volume: 93, Issue:1

    Topics: Aging; Animals; Arginine; Cattle; Collagen; Cross-Linking Reagents; Diet; Dogs; Glucose; Humans; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Rats; Regression Analysis; Saimiri; Skin; Swine

1996
Interaction of diet composition and a reduced nocturnal temperature regimen in weanling pigs.
    Journal of animal science, 1995, Volume: 73, Issue:9

    Topics: Aging; Analysis of Variance; Animal Feed; Animals; Body Temperature Regulation; Circadian Rhythm; Diet; Female; Lysine; Male; Random Allocation; Swine; Temperature; Weaning

1995
The impact of environment and antimicrobial agents on the growth response of early-weaned pigs to spray-dried porcine plasma.
    Journal of animal science, 1995, Volume: 73, Issue:9

    Topics: Aging; Animals; Anti-Bacterial Agents; Blood Proteins; Copper; Eating; Environment; Female; Hydrochloric Acid; Lysine; Male; Milk; Random Allocation; Swine; Weaning

1995
Evaluation of copper sulfate and a copper lysine complex as growth promoters for weanling swine.
    Journal of animal science, 1995, Volume: 73, Issue:9

    Topics: Aging; Animals; Brain Chemistry; Copper; Copper Sulfate; Diet; Eating; Female; Iron; Kidney; Liver; Lymphocyte Activation; Lysine; Male; Random Allocation; Swine; Weaning; Weight Gain; Zinc

1995
Interactive effects of feed intake and stage of growth on the lysine requirement of pigs.
    Journal of animal science, 1995, Volume: 73, Issue:11

    Topics: Aging; Animals; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Eating; Lysine; Male; Nutritional Requirements; Swine

1995
Direct quantification of pentosidine in urine and serum by HPLC with column switching.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Time Factors; Uremia

1996
Relative responses of protein turnover in three different skeletal muscles to dietary lysine deficiency in chicks.
    British poultry science, 1996, Volume: 37, Issue:3

    Topics: Aging; Analysis of Variance; Animal Feed; Animals; Chickens; Diet; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Tritium

1996
The role of glycation cross-links in diabetic vascular stiffening.
    Diabetologia, 1996, Volume: 39, Issue:8

    Topics: Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Elastin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Time Factors

1996
Effects of immune challenge, dietary energy density, and source of energy on performance and immunity in weanling pigs.
    Journal of animal science, 1996, Volume: 74, Issue:10

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antibodies; Cell Division; Dietary Fats; Energy Intake; Energy Metabolism; Escherichia coli; Female; Lipopolysaccharides; Lymphocytes; Lysine; Male; Swine; Threonine; Tryptophan; Weight Gain

1996
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
    Diabetologia, 1996, Volume: 39, Issue:12

    Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence

1996
[Activity of basic arginine- and lysine-residue cleaving carboxypeptidase in rats of various ages].
    Biokhimiia (Moscow, Russia), 1996, Volume: 61, Issue:10

    Topics: Aging; Animals; Arginine; Brain; Carboxypeptidases; Hydrolysis; Lysine; Male; Rats

1996
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
    The Journal of clinical investigation, 1997, Feb-01, Volume: 99, Issue:3

    Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E

1997
Influence of dietary lysine levels and arginine:lysine ratios on performance of broilers exposed to heat or cold stress during the period of three to six weeks of age.
    Poultry science, 1997, Volume: 76, Issue:3

    Topics: Aging; Animals; Arginine; Body Composition; Body Temperature; Chickens; Cold Temperature; Diet; Dose-Response Relationship, Drug; Eating; Hot Temperature; Lysine; Male; Meat; Poultry Diseases; Regression Analysis; Stress, Physiological; Time Factors; Weight Gain

1997
Dietary interactions between lysine and threonine in broilers.
    Poultry science, 1997, Volume: 76, Issue:4

    Topics: Aging; Animals; Antibody Formation; Body Composition; Chickens; Diet; Dose-Response Relationship, Drug; Drug Interactions; Immunity, Cellular; Lysine; Male; Meat; Mortality; Threonine; Time Factors; Weight Gain

1997
Age-related increase in an advanced glycation end product in penile tissue.
    World journal of urology, 1995, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Penile Erection; Penis; Sexual Dysfunction, Physiological

1995
Ageing promotes the increase of early glycation Amadori product as assessed by epsilon-N-(2-furoylmethyl)-L-lysine (furosine) levels in rodent skin collagen. The relationship to dietary restriction and glycoxidation.
    Mechanisms of ageing and development, 1997, Volume: 95, Issue:1-2

    Topics: Aging; Animals; Chromatography, High Pressure Liquid; Collagen; Diet; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Humans; Kinetics; Lysine; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Rats; Rats, Inbred F344; Skin

1997
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins.
    The Biochemical journal, 1997, Jun-01, Volume: 324 ( Pt 2)

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbohydrate Metabolism; Child; Collagen; Crystallins; Humans; Lens, Crystalline; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Ribonucleases; Skin

1997
Diphasic allometric growth of body components in white Leghorn pullets fed ad libitum and restricted diets.
    Poultry science, 1997, Volume: 76, Issue:7

    Topics: Aging; Animals; Body Composition; Chickens; Diet; Diet, Protein-Restricted; Dietary Proteins; Dose-Response Relationship, Drug; Eating; Female; Lysine; Models, Biological; Models, Statistical

1997
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
    Journal of animal science, 1997, Volume: 75, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays

1997
Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons.
    Biochemical and biophysical research communications, 1997, Jul-18, Volume: 236, Issue:2

    Topics: Adolescent; Aged; Aging; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipofuscin; Lysine; Nerve Degeneration; Nerve Tissue Proteins; Neurons

1997
Age-related association of tail tendon break time with tissue pentosidine in DBA/2 vs C57BL/6 mice: the effect of dietary restriction.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:5

    Topics: Aging; Animals; Arginine; Collagen; Diet; Female; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Denaturation; Species Specificity; Tail; Tendons; Time Factors

1997
Evaluation of protein and energy quality of rendered spent hen meals.
    Poultry science, 1997, Volume: 76, Issue:10

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Energy Intake; Lysine; Male; Methionine; Nutritive Value

1997
Effect of dietary aminoguanidine on tissue pentosidine and reproductive performance in broiler breeder hens.
    Poultry science, 1997, Volume: 76, Issue:11

    Topics: Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Chickens; Collagen; Diet; Egg Shell; Female; Fertility; Guanidines; Lysine; Male; Oviposition; Random Allocation; Reproduction; Skin; Specific Gravity

1997
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen.
    Analytical biochemistry, 1997, Nov-01, Volume: 253, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphyses; Dipeptides; Femur; Histidine; Humans; Indicators and Reagents; Infant; Lysine; Male; Middle Aged; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence

1997
Evaluation of the interrelationships among lactose and protein sources in diets for segregated early-weaned pigs.
    Journal of animal science, 1997, Volume: 75, Issue:12

    Topics: Aging; Animals; Blood Proteins; Diet; Dietary Proteins; Lactose; Lysine; Male; Probability; Random Allocation; Soybean Proteins; Swine; Weaning

1997
1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs.
    Spine, 1997, Dec-15, Volume: 22, Issue:24

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Child; Child, Preschool; Fetus; Humans; Immunohistochemistry; Infant; Infant, Newborn; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged

1997
Basal synthesis of heat shock protein 70 increases with age in rat kidneys.
    Gerontology, 1998, Volume: 44, Issue:1

    Topics: Actins; Aging; Animals; Arginine; HSP70 Heat-Shock Proteins; Kidney; Lysine; Male; Rats; Rats, Wistar; RNA, Messenger; RNA, Ribosomal

1998
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
    The Biochemical journal, 1998, Feb-15, Volume: 330 ( Pt 1)

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomechanical Phenomena; Cartilage, Articular; Child; Child, Preschool; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Hydroxylysine; Infant; Lysine; Middle Aged; Protein Processing, Post-Translational

1998
Advanced glycosylation end products in adrenal lipofuscin.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:1

    Topics: Adrenal Cortex; Adrenal Glands; Aging; Animals; Antibodies; Brain; Cerebellum; Cerebral Cortex; Cytoplasmic Granules; Fluorescent Antibody Technique, Direct; Glycation End Products, Advanced; Immunoenzyme Techniques; Immunohistochemistry; Lipofuscin; Lysine; Male; Neurons; Purkinje Cells; Rats; Rats, Inbred F344; Zona Reticularis

1998
Nonenzymatic glycation of cartilage proteoglycans: an in vivo and in vitro study.
    Glycoconjugate journal, 1997, Volume: 14, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Animals; Arginine; Cartilage; Cartilage, Articular; Cattle; Chromatography, Agarose; Cross-Linking Reagents; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Lectins, C-Type; Lysine; Middle Aged; Molecular Weight; Osteoarthritis; Proteoglycans

1997
Postnatal development of excitatory synaptic input to the rat neostriatum: an electron microscopic study.
    Neuroscience, 1998, Volume: 84, Issue:4

    Topics: Aging; Animals; Axons; Immunohistochemistry; Lysine; Microscopy, Electron; Neostriatum; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Synapses

1998
Role of advanced glycation end products in aging collagen. A scanning force microscope study.
    Gerontology, 1998, Volume: 44, Issue:4

    Topics: Aging; Animals; Arginine; Collagen; Glycation End Products, Advanced; Lysine; Male; Microscopy; Osmolar Concentration; Periodicity; Rats; Rats, Wistar; Tail; Tendons

1998
Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.
    The Journal of biological chemistry, 1998, Jul-24, Volume: 273, Issue:30

    Topics: Aging; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; In Vitro Techniques; Lysine; Maillard Reaction; Pyruvaldehyde; Ribonucleases

1998
Collagen crosslinks in human lumbar intervertebral disc aging.
    Spine, 1998, Aug-01, Volume: 23, Issue:15

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cadaver; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged

1998
Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains.
    Pathology international, 1998, Volume: 48, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Brain; Entorhinal Cortex; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Inclusion Bodies; Lipofuscin; Lysine; Maillard Reaction; Middle Aged; Ubiquitins

1998
The effect of dietary crude protein on growth, ammonia concentration, and litter composition in broilers.
    Poultry science, 1998, Volume: 77, Issue:10

    Topics: Aging; Amino Acids; Ammonia; Animal Feed; Animals; Chickens; Dietary Proteins; Food, Fortified; Lysine; Male; Waste Products; Weight Gain

1998
Determination of urinary and serum pentosidine and its application to elder patients.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:10

    Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Lysine; Middle Aged

1998
Effects of continuous ambulatory peritoneal dialysis and kidney transplantation on advanced glycation endproducts in the skin and peritoneum.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Skin; Spectrometry, Fluorescence

1998
Chemical modification of proteins by methylglyoxal.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia

1998
Changes in collagen cross-linking in degenerative disc disease and scoliosis.
    Spine, 1998, Dec-01, Volume: 23, Issue:23

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dipeptides; Extracellular Matrix; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged; Scoliosis

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen

1999
Early development of the motor and premotor circuitry of a sexually dimorphic vocal pathway in a teleost fish.
    Journal of neurobiology, 1999, Volume: 38, Issue:4

    Topics: Aging; Animals; Axonal Transport; Biotin; Embryo, Nonmammalian; Female; Fishes; Lysine; Male; Medulla Oblongata; Motor Neurons; Neural Pathways; Neurons; Rhombencephalon; Sex Characteristics; Swimming; Vocalization, Animal

1999
Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: an avian solution?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:4

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Enzyme Inhibitors; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Hyperglycemia; Leukocytes; Lysine; Oxidative Stress; Random Allocation; Respiratory Burst; Skin; Uric Acid

1999
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Cross-Linking Reagents; Extracellular Matrix; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Osteoarthritis; Proteoglycans; Ribose

1999
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis.
    Annals of the rheumatic diseases, 1999, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Child; Chronic Disease; Collagen; Cross-Linking Reagents; Humans; Hydroxylation; Hydroxylysine; Lysine; Middle Aged; Rotator Cuff; Tendinopathy

1999
Advanced glycation in D-galactose induced mouse aging model.
    Mechanisms of ageing and development, 1999, May-17, Volume: 108, Issue:3

    Topics: Aging; Animals; Avoidance Learning; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Female; Galactose; Glucose; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Interleukin-2; Learning; Lymphocytes; Lysine; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Nervous System Diseases; Skin; Superoxide Dismutase

1999
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
    Molecular vision, 1999, Jul-14, Volume: 5

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Arginine; Bruch Membrane; Cattle; Choroid Plexus; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Lysine; Middle Aged

1999
Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis.
    The Journal of biological chemistry, 1999, Jul-23, Volume: 274, Issue:30

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cataract; Child; Child, Preschool; Chromatography; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Fluorescence; Humans; Imidazoles; Infant; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged

1999
Conversion of lysine to N(epsilon)-(carboxymethyl)lysine increases susceptibility of proteins to metal-catalyzed oxidation.
    Biochemical and biophysical research communications, 1999, Oct-14, Volume: 264, Issue:1

    Topics: Aging; Animals; Catalysis; Cattle; Lysine; Metals; Oxidation-Reduction; Serum Albumin, Bovine

1999
Late embryonic expression of AMPA receptor function in the CA1 region of the intact hippocampus in vitro.
    The European journal of neuroscience, 1999, Volume: 11, Issue:11

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Aging; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Cations, Divalent; Electric Stimulation; Embryonic and Fetal Development; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Hypoxia; Lysine; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Tetrodotoxin

1999
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
    The international journal of biochemistry & cell biology, 1999, Volume: 31, Issue:11

    Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases

1999
Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus.
    Journal of neurophysiology, 2000, Volume: 83, Issue:3

    Topics: Aging; Animals; Carrier Proteins; Coloring Agents; Electrophysiology; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Lysine; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; N-Methylaspartate; Neurons; Organic Anion Transporters; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Superior Colliculi

2000
Effect of age and menopause on serum concentrations of pentosidine, an advanced glycation end product.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Lysine; Menopause; Middle Aged; Osteocalcin

2000
Accumulation of advanced glycation endproducts in aging male Fischer 344 rats during long-term feeding of various dietary carbohydrates.
    The Journal of nutrition, 2000, Volume: 130, Issue:5

    Topics: Aging; Animals; Arginine; Blood Glucose; Collagen; Cross-Linking Reagents; Dietary Carbohydrates; Dietary Sucrose; Energy Intake; Fructosamine; Fructose; Glucose; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Inbred F344; Skin; Starch

2000
Carnosine reacts with a glycated protein.
    Free radical biology & medicine, 2000, May-15, Volume: 28, Issue:10

    Topics: Aging; Animals; Carnosine; Glycoproteins; Glycosylation; Humans; In Vitro Techniques; Lysine; Ovalbumin; Oxidation-Reduction; Pyruvaldehyde

2000
Effects of adding dietary lysine to a low gluten diet on the brain protein synthesis rate in aged rats.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:7

    Topics: Aging; Animals; Body Weight; Brain; Dietary Supplements; Glutens; Lysine; Male; Protein Biosynthesis; Rats; Rats, Wistar; RNA

2000
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
    The Biochemical journal, 2000, Sep-01, Volume: 350 Pt 2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Child; Child, Preschool; Collagen; Collagenases; Cross-Linking Reagents; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Skin; Spectrometry, Fluorescence

2000
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins.
    Biochimica et biophysica acta, 2000, Sep-29, Volume: 1481, Issue:2

    Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human

2000
Identification of limiting amino acids in methionine- and lysine-supplemented low-protein diets for turkeys.
    Poultry science, 2000, Volume: 79, Issue:9

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Diet, Protein-Restricted; Dietary Supplements; Glycine max; Lysine; Male; Meat; Methionine; Nutritional Requirements; Turkeys; Weight Gain; Zea mays

2000
Interaction between ambient temperature and supplementation of synthetic amino acids on performance and carcass parameters in commercial male turkeys.
    Poultry science, 2000, Volume: 79, Issue:10

    Topics: Aging; Amino Acids; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Body Weight; Diet; Eating; Lysine; Male; Meat; Methionine; Temperature; Threonine; Turkeys; Weight Gain

2000
Intestinal transport of monosaccharides and amino acids during postnatal development of mink.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Aging; Amino Acids; Animals; Aspartic Acid; Body Weight; Female; Fructose; Glucose; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Lysine; Male; Methionine; Microvilli; Mink; Monosaccharides; Proline

2000
Isoleucine imbalance using selected mixtures of imbalancing amino acids in diets of the broiler chick.
    Poultry science, 2000, Volume: 79, Issue:12

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Composition; Chickens; Diet; Dietary Proteins; Eating; Isoleucine; Lysine; Male; Nutritional Requirements; Regression Analysis; Weight Gain

2000
Neuronal and glial advanced glycation end product [Nepsilon-(carboxymethyl)lysine]] in Alzheimer's disease brains.
    Acta neuropathologica, 2001, Volume: 101, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Neuroglia; Neurons

2001
Isolation and characterization of senescence-induced cDNAs encoding deoxyhypusine synthase and eucaryotic translation initiation factor 5A from tomato.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Aging; Amino Acid Sequence; Archaea; Base Sequence; Conserved Sequence; DNA, Complementary; Eukaryotic Translation Initiation Factor 5A; Fungi; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Library; Humans; Lysine; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Plant Leaves; Plant Stems; Plants; Recombinant Proteins; RNA-Binding Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Solanum lycopersicum

2001
Rapid anatomical plasticity of horizontal connections in the developing visual cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10

    Topics: Aging; Animals; Axons; Brain Mapping; Cats; Dominance, Cerebral; Exotropia; Lysine; Neural Pathways; Neuronal Plasticity; Presynaptic Terminals; Pyramidal Cells; Thalamus; Vision, Binocular; Visual Cortex; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate

2001
Accelerated tissue aging and increased oxidative stress in broiler chickens fed allopurinol.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 129, Issue:2

    Topics: Aging; Allopurinol; Animals; Antimetabolites; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Glycation End Products, Advanced; Glycosylation; Hemin; Luminescent Measurements; Lysine; Muscle, Skeletal; Oxidative Stress; Skin; Uric Acid

2001
Predominance of late-spiking neurons in layer VI of rat perirhinal cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-15, Volume: 21, Issue:14

    Topics: Action Potentials; Aging; Animals; In Vitro Techniques; Lysine; Male; Microscopy, Video; Neurons; Parahippocampal Gyrus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Sensory Thresholds

2001
Recurrent CA1 collateral axons in developing rat hippocampus.
    Brain research, 2001, Sep-21, Volume: 913, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Axons; Cell Differentiation; Cell Size; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; GABA Antagonists; Hippocampus; Immunohistochemistry; Lysine; Membrane Potentials; Nerve Net; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2001
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunity; Interferon-gamma; Isoproterenol; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysine; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Signal Transduction; Up-Regulation

2001
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
    Matrix biology : journal of the International Society for Matrix Biology, 2001, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chondroitin Sulfate Proteoglycans; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Lectins, C-Type; Lysine; Middle Aged; Osteoarthritis; Proteoglycans

2001
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Arginine; Arthritis, Rheumatoid; Cartilage, Articular; Cattle; Chromatography, High Pressure Liquid; Glycosaminoglycans; Humans; In Vitro Techniques; Knee Joint; Lysine; Matrix Metalloproteinases; Middle Aged; Osteoarthritis, Knee; Phenylmercuric Acetate; Ribose; Synovial Fluid

2001
Cholecystokinin-immunopositive basket and Schaffer collateral-associated interneurones target different domains of pyramidal cells in the CA1 area of the rat hippocampus.
    Neuroscience, 2002, Volume: 109, Issue:1

    Topics: Action Potentials; Aging; Animals; Animals, Newborn; Axons; Calbindins; Cholecystokinin; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Interneurons; Lysine; Male; Neural Inhibition; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Synaptic Transmission

2002
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:1

    Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses

2002
Development of individual axon arbors in a thalamocortical circuit necessary for song learning in zebra finches.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Feb-01, Volume: 22, Issue:3

    Topics: Aging; Animals; Axons; Cerebral Cortex; Immunohistochemistry; Learning; Lysine; Male; Nerve Net; Neuronal Plasticity; Songbirds; Thalamus; Vocalization, Animal

2002
[Levels of mature cross-links and advanced glycation end product cross-links in human vitreous].
    Nippon Ganka Gakkai zasshi, 2002, Volume: 106, Issue:1

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cross-Linking Reagents; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Vitreous Body

2002
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet.
    European journal of nutrition, 2001, Volume: 40, Issue:6

    Topics: Adult; Aging; Diabetes Mellitus; Diet; Diet, Vegetarian; Edible Grain; Enzyme-Linked Immunosorbent Assay; Fabaceae; Fluorescence; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Lysine

2001
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.
    Free radical research, 2002, Volume: 36, Issue:1

    Topics: Aging; Animals; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Food Deprivation; Gas Chromatography-Mass Spectrometry; Lysine; Male; Malondialdehyde; Mitochondria; Models, Statistical; Myocardium; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2002
Processing of dietary casein decreases bioavailability of lysine in growing kittens.
    The Journal of nutrition, 2002, Volume: 132, Issue:6 Suppl 2

    Topics: Aging; Animals; Animals, Newborn; Biological Availability; Caseins; Cats; Diet; Lysine

2002
Involvement of Cajal-Retzius cells in robust and layer-specific regeneration of the entorhino-hippocampal pathways.
    The European journal of neuroscience, 2002, Volume: 15, Issue:12

    Topics: Aging; Animals; Animals, Newborn; Axotomy; Body Patterning; Cell Communication; Coculture Techniques; Cues; Entorhinal Cortex; Growth Cones; Growth Substances; Hippocampus; Lysine; Mice; Mice, Inbred Strains; Microscopy, Electron; Nerve Regeneration; Neural Pathways; Neuronal Plasticity; Organ Culture Techniques; Presynaptic Terminals; Pyramidal Cells; Stem Cells

2002
[Hydroxylation of skin collagen in relation to age: analyses of the human skin].
    Aktuelle Gerontologie, 1977, Volume: 7, Issue:5

    Topics: Adult; Age Factors; Aging; Collagen; Female; Humans; Hydrolysis; Hydroxylation; Hydroxylysine; Hydroxyproline; Lysine; Middle Aged; Proline; Skin

1977
Synthesis of myelin basic proteins in the developing mouse brain.
    Archives of biochemistry and biophysics, 1978, Volume: 190, Issue:1

    Topics: Aging; Animals; Brain; Female; Kinetics; Lysine; Male; Mice; Myelin Basic Protein

1978
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
    Journal of developmental physiology, 1979, Volume: 1, Issue:2

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine

1979
Age dependence of the biosynthesis of intercellular matrix macromolecules of rabbit aorta in organ culture and cell culture.
    Gerontology, 1976, Volume: 22, Issue:6

    Topics: Aging; Animals; Aorta; Cells, Cultured; Desmosine; Elastin; Glucosamine; Glycoproteins; Glycosaminoglycans; Lysine; Macromolecular Substances; Organ Culture Techniques; Rabbits

1976
[Structural and biochemical alterations of human diabetic dermis studied by H-lysine incorporation and microscopy].
    Pathologie-biologie, 1976, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aging; Biopsy; Buffers; Calcium Chloride; Child; Collagen; Cytoplasm; Diabetes Mellitus; Elastin; Endoplasmic Reticulum; Fibroblasts; Glycoproteins; Humans; Hydroxyproline; Intercellular Junctions; Lysine; Microbial Collagenase; Pancreatic Elastase; Skin; Tritium; Urea

1976
Age-related changes in function of transfer ribonucleic acid of rat livers.
    Federation proceedings, 1979, Volume: 38, Issue:6

    Topics: Acylation; Aging; Animals; Liver; Lysine; Protein Biosynthesis; Rats; Ribosomes; RNA, Transfer; Serine

1979
Developmental and other characteristics of lysine uptake by rat brain synaptosomes.
    Biochimica et biophysica acta, 1979, Nov-02, Volume: 557, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Brain; Kinetics; Lysine; Male; Rats; Sodium; Synaptosomes

1979
Biosynthesis of collagen crosslinks in rabbit articular cartilage in vivo.
    Archives of biochemistry and biophysics, 1979, Volume: 198, Issue:1

    Topics: Aging; Animals; Cartilage, Articular; Collagen; Cross-Linking Reagents; Lysine; Macromolecular Substances; Rabbits

1979
The nucleosome repeat length increases during erythropoiesis in the chick.
    Nucleic acids research, 1978, Volume: 5, Issue:4

    Topics: Aging; Animals; Chick Embryo; Chickens; DNA; Erythroblasts; Erythrocytes; Erythropoiesis; Histones; Leucine; Lysine; Nucleoproteins

1978
Ontogenetic changes in the content of methylated amino acids in rodent skeletal muscle.
    Experimental gerontology, 1977, Volume: 12, Issue:5-6

    Topics: Aging; Animals; Arginine; Cricetinae; Histidine; Lysine; Male; Methylation; Methylhistidines; Mice; Muscle Development; Muscles; Myosins; Rats

1977
Studies on the rat glomerular basement membrane: age-related changes in composition.
    Archives of biochemistry and biophysics, 1978, Jan-30, Volume: 185, Issue:2

    Topics: Aging; Amino Acids; Animals; Basement Membrane; Female; Glycine; Hydroxylysine; Hydroxyproline; Kidney Glomerulus; Lysine; Male; Proline; Rats; Sodium Dodecyl Sulfate

1978
The effect of age on amino acid composition of human skin collagen.
    Journal of gerontology, 1978, Volume: 33, Issue:4

    Topics: Adult; Age Factors; Aged; Aging; Aldehydes; Amino Acids; Child; Collagen; Cysteine; Female; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Lysine; Middle Aged; Proline; Skin

1978
Age-related changes in the reducible cross-links of human dermis collagen.
    Dermatologica, 1977, Volume: 155, Issue:6

    Topics: Adult; Age Factors; Aged; Aging; Borohydrides; Child, Preschool; Collagen; Desmosine; Humans; Infant, Newborn; Lysine; Middle Aged; Norleucine; Skin

1977
Aging of human bone and articular cartilage collagen: changes in the reducible cross-links and their precursors.
    Gerontology, 1976, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Bone and Bones; Cartilage, Articular; Child; Child, Preschool; Collagen; Humans; Leucine; Lysine; Middle Aged; Solubility

1976
[Changes in subfraction composition of chicken lysine-rich histone during ontogenesis].
    Biokhimiia (Moscow, Russia), 1976, Volume: 41, Issue:5

    Topics: Aging; Animals; Brain Chemistry; Chemical Fractionation; Chick Embryo; Chickens; DNA; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Histones; Intestinal Mucosa; Intestine, Small; Liver; Lysine; Male; Myocardium; Organ Size; Testis; Thymus Gland

1976
Decrease in cold tolerance of aged rats caused by the enhanced endogenous adenosine activity.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Body Temperature Regulation; Cold Temperature; Lysine; Male; Neck Muscles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines

1992
Contribution of skin to whole-body protein synthesis in rats at different stages of maturity.
    The Journal of nutrition, 1992, Volume: 122, Issue:11

    Topics: Aging; Animals; Body Composition; Lysine; Male; Muscle Development; Muscles; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Skin

1992
Developmental changes of L-lysine-ketoglutarate reductase in rat brain and liver.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1992, Volume: 103, Issue:1

    Topics: Aging; Animals; Brain; Enzyme Induction; Gestational Age; Glucagon; Liver; Lysine; Rats; Rats, Sprague-Dawley; Saccharopine Dehydrogenases; Succinate Dehydrogenase

1992
Developing corticorubral axons of the cat form synapses on filopodial dendritic protrusions.
    Neuroscience letters, 1992, Nov-23, Volume: 147, Issue:1

    Topics: Aging; Animals; Axons; Cats; Cerebral Cortex; Dendrites; Histocytochemistry; Lysine; Microscopy, Electron; Synapses

1992
Fluorophores from aging human articular cartilage.
    Journal of biochemistry, 1991, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Female; Humans; Lysine; Male; Microbial Collagenase; Middle Aged; Solubility; Spectrometry, Fluorescence

1991
Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen.
    Biochemistry, 1991, Feb-05, Volume: 30, Issue:5

    Topics: Aging; Collagen; Gas Chromatography-Mass Spectrometry; Glycosylation; Humans; Hydroxylysine; Lens, Crystalline; Lysine; Oxidation-Reduction; Skin

1991
Effect of diabetes and aging on carboxymethyllysine levels in human urine.
    Diabetes, 1991, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Diabetes Mellitus, Type 1; Humans; Lysine; Middle Aged; Oxidation-Reduction

1991
Change in the amount of epsilon-hexosyllysine, UV absorbance, and fluorescence of collagen with age in different animal species.
    Journal of gerontology, 1991, Volume: 46, Issue:3

    Topics: Aging; Animals; Aorta; Cats; Chromatography, Affinity; Collagen; Dogs; Furaldehyde; Glycosylation; Horses; Humans; Lysine; Mice; Skin; Species Specificity; Spectrometry, Fluorescence; Sugar Acids; Thiobarbiturates; Ultraviolet Rays

1991
Change with age of UV absorbance and fluorescence of collagen and accumulation of epsilon-hexosyllysine in collagen from Wistar rats living on different food restriction regimes.
    Mechanisms of ageing and development, 1991, Volume: 57, Issue:2

    Topics: Aging; Animals; Aorta, Thoracic; Collagen; Food Deprivation; Glycosylation; Hexoses; Longevity; Lysine; Pigmentation; Rats; Rats, Inbred Strains; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1991
Alterations of biochemical and biomechanical properties of rat tail tendons caused by non-enzymatic glycation and their inhibition by dibasic amino acids arginine and lysine.
    Diabetologia, 1991, Volume: 34, Issue:1

    Topics: Aging; Animals; Arginine; Fructosamine; Glucose; Glycosylation; Hexosamines; In Vitro Techniques; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Stress, Mechanical; Tail; Tendons

1991
Collagen in the ageing human intervertebral disc: an increase in covalently bound fluorophores and chromophores.
    Biochimica et biophysica acta, 1991, Jun-24, Volume: 1078, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Color; Cyanogen Bromide; Female; Humans; Hydroxylysine; Intervertebral Disc; Lysine; Middle Aged; Molecular Sequence Data; Papain; Spectrometry, Fluorescence

1991
Analysis of age-associated alteration in the synthesis of HMG nonhistone proteins of the rat liver.
    Molecular biology reports, 1991, Volume: 15, Issue:1

    Topics: Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Electrophoresis, Polyacrylamide Gel; High Mobility Group Proteins; In Vitro Techniques; Liver; Lysine; Male; Rats; Rats, Inbred Strains; Spermine

1991
High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-15, Volume: 88, Issue:22

    Topics: Adult; Aged; Aging; Animals; Arginine; Ascorbic Acid; Cataract; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Crystallins; Humans; Hydrolysis; Lens, Crystalline; Lysine; Models, Biological; Molecular Weight; Pigmentation; Reference Values

1991
Changes with age in the urinary excretion of lysyl- and hydroxylysylpyridinoline, two new markers of bone collagen turnover.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5, Issue:7

    Topics: Adult; Aged; Aging; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Hydrolysis; Hydroxylysine; Lysine; Male; Middle Aged; Pyridinium Compounds; Reference Standards; Reference Values

1990
Age- and diabetes-accelerated glycation in the human aorta.
    Archives of gerontology and geriatrics, 1989, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aorta; Arteriosclerosis; Diabetes Mellitus, Type 2; Female; Humans; Infant, Newborn; Lysine; Maillard Reaction; Male; Middle Aged

1989
[Role of the non-enzymatic glycosylation of protein in the formation of human cataracts].
    Bollettino della Societa italiana di biologia sperimentale, 1989, Volume: 65, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Diabetes Mellitus, Type 2; Eye Proteins; Female; Glycosylation; Humans; Lysine; Male; Middle Aged; Schiff Bases

1989
Glycation of collagen in the aorta and the development of aging.
    Clinica chimica acta; international journal of clinical chemistry, 1989, Jun-30, Volume: 182, Issue:2

    Topics: Aged; Aging; Animals; Aorta, Abdominal; Collagen; Diabetes Mellitus, Type 2; Fluorescence; Glycosylation; Humans; Lysine; Maillard Reaction; Middle Aged; Rats

1989
Inactivation of erythrocyte Cu-Zn-superoxide dismutase through nonenzymatic glycosylation.
    Progress in clinical and biological research, 1989, Volume: 304

    Topics: Adult; Aging; Amino Acids; Enzyme Stability; Erythrocytes; Glycosylation; Hot Temperature; Humans; Hyperglycemia; Lysine; Male; Peptide Mapping; Superoxide Dismutase; Werner Syndrome

1989
Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.
    The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29

    Topics: Aging; Animals; Arginine; Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Histidine; Immunosorbent Techniques; Liver; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1989
Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Aging; Animals; Arginine; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dura Mater; Extracellular Matrix; Hexoses; Humans; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organ Specificity; Pentoses; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1989
Oxidation of glycated proteins: age-dependent accumulation of N epsilon-(carboxymethyl)lysine in lens proteins.
    Biochemistry, 1989, Nov-28, Volume: 28, Issue:24

    Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography, Ion Exchange; Crystallins; Humans; Infant; Lysine; Middle Aged; Oxidation-Reduction

1989
A study of the age-related acceleration of glycation of tissue proteins in rats.
    Journal of gerontology, 1988, Volume: 43, Issue:4

    Topics: Aging; Animals; Aorta; Carbohydrate Metabolism; Chromatography, Affinity; Chromatography, High Pressure Liquid; Fluorescence; Glycated Hemoglobin; Lysine; Male; Proteins; Rats; Rats, Inbred Strains; Specific Pathogen-Free Organisms

1988
Age-related acceleration of glycation of tissue proteins in rats.
    Journal of gerontology, 1986, Volume: 41, Issue:6

    Topics: Aging; Animals; Aorta; Glycated Hemoglobin; Glycosylation; Lysine; Male; Rats; Rats, Inbred Strains; Sciatic Nerve

1986
Recovery of age-related decline of thymic endocrine activity and PHA response by lysin-arginine combination.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:7

    Topics: Aging; Amino Acids; Animals; Arginine; Cytotoxicity Tests, Immunologic; Lysine; Male; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Thymic Factor, Circulating; Thymus Gland; Thymus Hormones

1986
gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant.
    The Journal of nutrition, 1987, Volume: 117, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Betaine; Carnitine; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Humans; Infant; Infant, Newborn; Kidney; Liver; Lysine; Male; Middle Aged; Mixed Function Oxygenases

1987
Chemistry of the collagen cross-links. Origin and partial characterization of a putative mature cross-link of collagen.
    The Biochemical journal, 1987, Jun-01, Volume: 244, Issue:2

    Topics: Aging; Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Collagen; Electrophoresis, Paper; In Vitro Techniques; Lysine; Mass Spectrometry; Rabbits; Sheep; Skin

1987
Aging and cross-linking of skin collagen.
    Biochemical and biophysical research communications, 1988, Apr-29, Volume: 152, Issue:2

    Topics: Adult; Aged; Aging; Amino Acids; Animals; Cattle; Collagen; Cross-Linking Reagents; Histidine; Humans; Infant; Lysine; Macromolecular Substances; Norleucine; Skin; Skin Physiological Phenomena

1988
Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.
    The Journal of biological chemistry, 1988, Jun-15, Volume: 263, Issue:17

    Topics: Aging; Animals; Arginine; Histidine; Kinetics; Liver; Lysine; Malate Dehydrogenase; Methionine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds

1988
Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats.
    The British journal of nutrition, 1988, Volume: 60, Issue:2

    Topics: Aging; Amino Acids; Animals; Caseins; Dietary Proteins; Leucine; Lysine; Male; Methylhistidines; Nitrogen; Peptides; Proline; Rats; Rats, Inbred Strains; Tryptophan; Valine

1988
Age-related and diabetes-associated glycation in tissue proteins.
    The Kobe journal of medical sciences, 1988, Volume: 34, Issue:4

    Topics: Aging; Animals; Aorta; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Glycosylation; Lysine; Maillard Reaction; Male; Proteins; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1988
Collagen-glycation in the aorta as a developmental factor of aging and arteriosclerosis.
    The Kobe journal of medical sciences, 1988, Volume: 34, Issue:4

    Topics: Aging; Aorta; Arteriosclerosis; Collagen; Diabetes Mellitus, Type 2; Glycosylation; Humans; Lysine; Maillard Reaction; Spectrometry, Fluorescence

1988
Ontogeny modifies manifestations of cystinuria genes: implications for counseling.
    The Journal of pediatrics, 1985, Volume: 106, Issue:3

    Topics: Aging; Amino Acids; Arginine; Cystinuria; Follow-Up Studies; Genetic Counseling; Genotype; Humans; Infant, Newborn; Lysine; Ornithine; Phenotype; Quebec

1985
Protein utilization in growth: effect of lysine deficiency on serum growth hormone, somatomedins, insulin, total thyroxine (T4) and triiodothyronine, free T4 index, and total corticosterone.
    Endocrinology, 1985, Volume: 117, Issue:2

    Topics: Aging; Animals; Body Weight; Corticosterone; Eating; Growth Hormone; Insulin; Lysine; Male; Proteins; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatomedins; Thyroxine; Triiodothyronine

1985
Turnover of myelin and other structural proteins in the developing rat brain.
    The Biochemical journal, 1974, Volume: 142, Issue:3

    Topics: Aging; Animals; Brain; Drug Stability; Electrophoresis, Disc; Glucose; Half-Life; Lysine; Male; Microscopy, Electron; Molecular Weight; Myelin Basic Protein; Myelin Sheath; Nerve Tissue Proteins; Rats; Subcellular Fractions; Time Factors

1974
Beta2-microglobulin: occurrence in fetal life and malignancy.
    Clinica chimica acta; international journal of clinical chemistry, 1974, May-17, Volume: 52, Issue:3

    Topics: Aging; Carbon Radioisotopes; Female; Fetal Proteins; Fetus; Gestational Age; Humans; Immunodiffusion; Infant, Newborn; Infant, Premature; Isoleucine; Leukemia; Lysine; Maternal-Fetal Exchange; Neoplasms; Pregnancy; Serum Globulins; Umbilical Cord

1974
Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and cell division in mammalian tissues.
    Biochemistry, 1973, Sep-25, Volume: 12, Issue:20

    Topics: Aging; Animals; Bone Marrow; Brain; Carcinoma, Hepatocellular; Cattle; Cell Division; Cells, Cultured; Chromatography, Ion Exchange; Female; Fetus; Lens, Crystalline; Leukemia; Liver; Liver Neoplasms; Lysine; Mice; Neoplasms, Experimental; Organ Specificity; Pancreas; Pregnancy; Rats; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet; Spleen; Swine; Tritium

1973
Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.
    Journal of neurochemistry, 1974, Volume: 23, Issue:5

    Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Chick Embryo; Chickens; Glutamates; Leucyl Aminopeptidase; Lysine; Naphthols; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Sciatic Nerve; Time Factors

1974
Measurements of rates of protein synthesis in rat brain slices.
    Journal of neurochemistry, 1974, Volume: 22, Issue:5

    Topics: Aging; Amino Acids; Animals; Brain; Carbon Radioisotopes; Histidine; In Vitro Techniques; Kinetics; Leucine; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Time Factors; Tritium; Valine

1974
In vivo methylation and turnover of rat brain histones.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Half-Life; Histones; Lysine; Male; Methionine; Methylation; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; Regression Analysis; Time Factors; Tritium

1974
Increased incorporation of 14C-lysine into vascular proteins of the spontaneously hypertensive rat.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: Actomyosin; Aging; Animals; Aorta; Blood Pressure; Blood Proteins; Body Weight; Carbon Radioisotopes; Elastin; Hypertension; Kinetics; Liver; Lysine; Male; Myocardium; Organ Size; Rats; Rats, Inbred Strains; Time Factors

1974
Epsilon-alkyllysinase. New assay method, purification, and biological significance.
    Archives of biochemistry and biophysics, 1974, Volume: 165, Issue:1

    Topics: Aging; Animals; Body Weight; Carbon Radioisotopes; Chromatography, Gel; Drug Stability; Freezing; Histones; Hot Temperature; Kidney; Kinetics; Liver; Lysine; Oxidoreductases, N-Demethylating; Polyethylene Glycols; Rats; Time Factors

1974
Further data on the age-dependent intestinal absorption of dibasic amino acids.
    Experimental gerontology, 1974, Volume: 9, Issue:5-6

    Topics: Aging; Amino Acids; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestines; Lysine; Organ Size; Rats

1974
Changes in transfer RNAs and aminoacyl-tRNA synthetases during sea urchin development.
    Biochimica et biophysica acta, 1973, Jul-27, Volume: 312, Issue:4

    Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Embryo, Nonmammalian; Female; Fertilization; Leucine; Lysine; Ovum; RNA, Transfer; Saccharomyces cerevisiae; Sea Urchins; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tritium

1973
Protein turnover of the lysosomal and mitochondrial fractions of rat liver during aging.
    Experimental gerontology, 1972, Volume: 7, Issue:6

    Topics: Aging; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Liver; Lysine; Lysosomes; Male; Microsomes, Liver; Mitochondria, Liver; Proteins; Rats; Tritium

1972
Protein methylase 3 of rat kidney during the early development.
    FEBS letters, 1973, Sep-15, Volume: 35, Issue:2

    Topics: Aging; Animals; Carbon Radioisotopes; Cell Nucleus; DNA; Female; Fetus; Kidney; Lysine; Methyltransferases; Pregnancy; Proteins; Rats; S-Adenosylmethionine

1973
Protein methylases during the development of rat brain.
    Biochimica et biophysica acta, 1973, Jun-20, Volume: 313, Issue:1

    Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium

1973
Assay of protocollagen lysyl hydroxylase activity in the skin of human subjects and changes in the activity with age.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Aug-30, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Animals; Carbon Radioisotopes; Chick Embryo; Child; Child, Preschool; Collagen; Female; Fetus; Humans; Hydroxylysine; Infant; Infant, Newborn; Ketoglutaric Acids; Lysine; Middle Aged; Mixed Function Oxygenases; Pregnancy; Protein Precursors; Skin; Subcellular Fractions

1973
Synthesis of type I and type II collagen by embryonic chick cartilage.
    Biochemical and biophysical research communications, 1974, May-07, Volume: 58, Issue:1

    Topics: Aging; Animals; Autoradiography; Carbon Radioisotopes; Cartilage; Cartilage, Articular; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Collagen; Hydroxylation; Lysine; Proline; Thymidine; Time Factors; Tritium; Uridine

1974
[Aortic elastin and its variations during senescence and arteriosclerosis].
    Pathologie-biologie, 1970, Volume: 18, Issue:1

    Topics: Aging; Amino Acids; Animals; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cattle; Elastin; Glutamates; Lysine; Rabbits

1970
Age-related alterations in the structure of nucleoprotein. IV. Changes in the compoistion of whole histone from rat liver.
    Gerontologia, 1969, Volume: 15, Issue:4

    Topics: Age Factors; Aging; Animals; Arginine; DNA; Edetic Acid; Female; Histones; Immunodiffusion; Liver; Lysine; Methods; Nucleoproteins; Rats; Temperature

1969
Synthesis of aldehydes and their interactions during the in vitro aging of collagen.
    Biochemistry, 1971, Jun-08, Volume: 10, Issue:12

    Topics: Acetates; Adipates; Aging; Aldehydes; Amines; Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Cysteamine; Edetic Acid; Hot Temperature; In Vitro Techniques; Isoniazid; Lysine; Male; Penicillamine; Rats; Schiff Bases; Skin; Solubility; Tritium

1971
[Distribution of two peptides of -aminobutyric acid in human brain and CSF].
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Aminobutyrates; Brain Chemistry; Cerebral Cortex; Child; Child, Preschool; Chromatography, Ion Exchange; Dipeptides; Histidine; Humans; Infant; Lysine; Middle Aged; Parkinson Disease; Phenylketonurias

1972
Age-related changes in collagen: the identification of reducible lysine-carbohydrate condensation products.
    Biochemical and biophysical research communications, 1972, Jul-11, Volume: 48, Issue:1

    Topics: Aging; Animals; Borohydrides; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Galactose; Glucose; Lysine; Mannitol; Mass Spectrometry; Oxidation-Reduction; Skin; Sugar Alcohols; Tritium

1972
The isolation and partial characterization of age-correlated oligo-deoxyribo-ribonucleotides with covalently linked aspartyl-glutamyl polypeptides.
    Johns Hopkins medical journal. Supplement, 1972, Issue:1

    Topics: Aging; Animals; Aspartic Acid; Brain Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyribonucleotides; Female; Glutamates; Liver; Lysine; Male; Methods; Molecular Weight; Nucleotides; Peptides; Rats; Spectrophotometry; Spectrum Analysis; Tritium; Ultraviolet Rays

1972
Biochemical studies on the aging of rat tail tendon.
    Gerontologia, 1971, Volume: 17, Issue:2

    Topics: Aging; Animals; Arginine; Calcium Chloride; Collagen; Fucose; Galactose; Glucose; Glycoproteins; Glycosides; Hexosamines; Hexoses; Hydroxyproline; Lysine; Mannose; Proteins; Rats; Tail; Tendons; Time Factors; Xylose

1971
Protein metabolism in aging mice.
    Journal of gerontology, 1971, Volume: 26, Issue:4

    Topics: Aging; Animals; Carbon Isotopes; Injections, Intraperitoneal; Lysine; Male; Mice; Proteins

1971
Is protein catabolism nonrandom?
    Experientia, 1971, Oct-15, Volume: 27, Issue:10

    Topics: Aging; Animals; Carbon Isotopes; Lysine; Male; Mice; Proteins; Starvation; Time Factors

1971
Influence of age on insulin stimulation of amino acid uptake in rat diaphragm.
    The Journal of biological chemistry, 1971, Volume: 246, Issue:21

    Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Diaphragm; Drug Antagonism; Extracellular Space; In Vitro Techniques; Insulin; Inulin; Kinetics; Lysine; Male; Models, Biological; Muscle Proteins; Muscles; Puromycin; Rats; Stimulation, Chemical; Time Factors

1971
Some factors influencing the aggregating property of collagen.
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Aging; Animals; Blood Platelets; Carbohydrates; Cattle; Collagen; Humans; Hydroxyproline; Lysine; Organ Specificity; Platelet Adhesiveness; Polymers; Species Specificity; Spectrum Analysis

1971
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966
The influence of endotoxin administration on the nutritional requirements of mice.
    The Journal of experimental medicine, 1965, Nov-01, Volume: 122, Issue:5

    Topics: Aging; Amino Acids; Animals; Body Weight; Dietary Proteins; Endotoxins; Escherichia coli; Glutens; Lysine; Methionine; Mice; Nutritional Physiological Phenomena; Threonine; Valine

1965
The heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels.
    Biochemistry, 1969, Volume: 8, Issue:10

    Topics: Acrylates; Aging; Animals; Brain Chemistry; Cattle; Densitometry; Electrophoresis; Endometrium; Female; Histones; Intestines; Kidney; Liver; Lung; Lysine; Male; Organ Specificity; Sex Factors; Spleen; Sulfides

1969
Effect of concentration on the intestinal absorption of l-lysine in ageing rats.
    Experimental gerontology, 1969, Volume: 4, Issue:4

    Topics: Aging; Animals; Carbon Isotopes; Intestinal Absorption; Lysine; Rats

1969
Biosynthesis of collagen fibres.
    Clinical science, 1970, Volume: 38, Issue:2

    Topics: Aging; Aspartic Acid; Collagen; Galactose; Glucose; Glutamates; Glycoproteins; Lysine; Proline

1970
Catalytic activities of thermally prepared poly-alpha-amino acids: effect of aging.
    Science (New York, N.Y.), 1970, Sep-04, Volume: 169, Issue:3949

    Topics: Aging; Biological Evolution; Catalysis; Chemical Phenomena; Chemistry; Hot Temperature; Lysine; Oxaloacetates; Peptides; Phenylacetates; Spectrophotometry; Time Factors

1970
Cerebral amino acid transport in vitro during development: a kinetic analysis.
    Archives of biochemistry and biophysics, 1970, Volume: 138, Issue:1

    Topics: Aging; Amino Acids; Aminobutyrates; Animals; Biological Transport; Brain; Brain Chemistry; Chick Embryo; Chickens; Glutamates; In Vitro Techniques; Kinetics; Leucine; Lysine

1970
The biosynthesis of protamine in trout testis. II. Polysome patterns and protein synthetic activities during testis maturation.
    The Journal of biological chemistry, 1970, Volume: 245, Issue:12

    Topics: Aging; Animals; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Liver; Lysine; Magnesium; Male; Protamines; Ribonucleases; Ribosomes; Salmonidae; Seasons; Testis; Ultracentrifugation

1970
Putreanine excretion in human urine.
    Biochimica et biophysica acta, 1970, Nov-24, Volume: 222, Issue:2

    Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autoanalysis; Child; Child, Preschool; Chromatography, Paper; Electrophoresis; Female; Humans; Lysine; Male; Middle Aged; Sex Factors

1970
Effect of ageing on amino acid turnover and rate of protein synthesis in the blowfly Phormia regina.
    Journal of insect physiology, 1971, Volume: 17, Issue:1

    Topics: Aging; Alanine; Amino Acids; Animals; Carbon Isotopes; Diptera; Lysine; Protein Biosynthesis; Time Factors

1971
Studies on the biosynthesis of the hydroxylysine-linked disaccharide unit of basement membranes and collagens. 3. Tissue and subcellular distribution of glycosyltransferases and the effect of various conditions on the enzyme levels.
    The Journal of biological chemistry, 1971, Aug-25, Volume: 246, Issue:16

    Topics: Acetates; Aging; Amino Alcohols; Animals; Animals, Newborn; Basement Membrane; Brain; Carbon Isotopes; Cartilage, Articular; Cell Fractionation; Chromatography, Gel; Chromatography, Paper; Collagen; Diabetes Mellitus, Experimental; Disaccharides; Female; Galactose; Glucosamine; Glucose; Glucosyltransferases; Kidney; Liver; Lysine; Male; Myocardium; Nucleoside Diphosphate Sugars; Organ Specificity; Pregnancy; Rats; Skin; Spleen; Thyroid Gland; Transferases; Uracil Nucleotides; Uterus

1971
Insulin stimulation of amino acid uptake in rat diaphragm. Relationship to protein sythesis.
    The Journal of biological chemistry, 1968, Apr-25, Volume: 243, Issue:8

    Topics: Aging; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes; Cycloheximide; Cycloparaffins; Dactinomycin; Diaphragm; In Vitro Techniques; Insulin; Kinetics; Lysine; Male; Nitrogen; Nucleosides; Oxygen Consumption; Protein Biosynthesis; Puromycin; Rats; Time Factors

1968
Studies on the histones and DNA of calf and old cow thymus.
    Journal of gerontology, 1968, Volume: 23, Issue:4

    Topics: Aging; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Cesium; Chromosomes; DNA; Histocytochemistry; Histones; Lysine; Molecular Biology; Spectrophotometry; Thymus Gland

1968
The lens capsule. Sugar and amino acid composition.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Aging; Amino Acids; Animals; Carbohydrates; Cattle; Collagen; Fucose; Galactose; Glucosamine; Glucose; Glycine; Hexosamines; Hydrogen-Ion Concentration; Hydroxyproline; Kidney Glomerulus; Lens, Crystalline; Lysine; Mannose; Membranes; Neuraminic Acids; Peptides; Proline; Solubility; Uronic Acids; Vibration

1969
Delineation of separate transport systems in rat kidney cortex for L-lysine and L-cystine by developmental patterns.
    Biochemical and biophysical research communications, 1969, Jun-06, Volume: 35, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Carbon Isotopes; Cystine; Kidney; Lysine; Rats; Sodium; Sulfur Isotopes; Tromethamine

1969
[Contribution to the therapeutic study of senescence].
    Semaine therapeutique, 1964, Volume: 40, Issue:2

    Topics: Aged; Aging; Blood Protein Disorders; Humans; Lysine; Nutrition Disorders; Protein Deficiency

1964
Effect of age and nephrectomy on epsilon-lysine acylase of rat kidney.
    Nature, 1966, May-14, Volume: 210, Issue:5037

    Topics: Acid Phosphatase; Aging; Animals; Carboxypeptidases; Kidney; Lysine; Nephrectomy; Rats

1966
Biochemistry of the developing rat brain. 8. Changes in the ribosomal system and nuclear RNA's.
    Biochimica et biophysica acta, 1966, Dec-21, Volume: 129, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Hydrogen-Ion Concentration; Lysine; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Ultraviolet Rays

1966
[The formation of the feedback inhibition of pancreatic secretion in ontogeny].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1990, Volume: 76, Issue:4

    Topics: Aging; Amylases; Animals; Depression, Chemical; Dogs; Feedback; Lipase; Pancreas; Pancreatic Juice; Protein Hydrolysates; Secretin; Trypsin

1990