lysine has been researched along with Aging in 414 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 115 (27.78) | 18.7374 |
| 1990's | 93 (22.46) | 18.2507 |
| 2000's | 97 (23.43) | 29.6817 |
| 2010's | 82 (19.81) | 24.3611 |
| 2020's | 27 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, JF; Wu, Y; Yang, JT; Yang, YH | 1 |
| Baldensperger, T; Dau, T; Di Sanzo, S; Glomb, MA; Heller, R; Henning, C; Kirkpatrick, JM; Leheis, A; Marx, C; Ori, A; Parca, L; Rändler, TL; Spengler, K; Wang, ZQ | 1 |
| Addicks, GC; Auwerx, J; Green, AE; Kang, BE; Katsyuba, E; Kim, D; Marshall, PL; Menzies, KJ; Patel, S; Renaud, JM; Ryu, D; Vasam, G; Williams, EG; Zhang, H | 1 |
| Jakhotia, S; Reddy Addi, U; Reddy, GB; Reddy, SS | 1 |
| Bařinka, C; Meleshin, M; Praetorius, L; Schutkowski, M; Sippl, W; Zessin, M | 1 |
| Liu, C; Liu, L; Wang, X; Zhao, T | 1 |
| He, J; Hu, L; Huang, J; Le, M; Li, J; Luo, T; Yuan, Y; Zhang, D; Zheng, L; Zhou, C | 1 |
| Ding, W; Feng, J; Gao, H; Gao, W; Li, X; Ling, M; Song, Y; Sun, Y; Tang, C; Wang, S; Xing, Y; Yan, R; Yang, X; Yu, N; Zhang, Z | 1 |
| Aref-Eshghi, E; Bonder, MJ; Choufani, S; Martin-Herranz, DE; Reik, W; Sadikovic, B; Stegle, O; Stubbs, TM; Thornton, JM; Weksberg, R | 1 |
| Alonso, AP; Cocuron, JC; Cooper, GL; Hoffman, CN; Huseby, CJ; Kuret, J; Thomas, SN; Yang, AJ | 1 |
| Golian, A; Nikbakhtzade, M; Zarghi, H | 1 |
| Fritz, KS; Michel, C; Nagaraj, RH; Nahomi, RB; Nandi, SK; Rakete, S | 1 |
| Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L | 1 |
| Hedtke, T; Heinz, A; Schmelzer, CEH | 1 |
| Bernabeu, R; Faillace, MP; Pisera-Fuster, A | 1 |
| Matsushita, K; Tamura, M; Ukita, M; Yamaguchi, T | 1 |
| Cai, SQ; Chang, SY; Chen, Z; Cheng, X; Gao, G; Hao, P; Jiang, L; Jiang, Q; Kang, XL; Lin, DY; Liu, XJ; Liu, ZY; Ye, SW; Yin, JA; Yin, SG; Yuan, J | 1 |
| Dong, Q; He, Q; Li, Y; Lv, C; Ming, X; Wang, H; Yi, Y; Zhang, Z; Zhu, B; Zou, Z | 1 |
| Binda, C; Edmondson, DE; Iacovino, LG; Manzella, N; Mattevi, A; Mialet-Perez, J; Parini, A; Pisani, L; Resta, J; Rotilio, L; Vanoni, MA | 1 |
| Alimova, I; Balakrishnan, I; Birks, DK; Carcaboso, AM; Dahl, N; Danis, E; Davidson, N; Donson, A; Foreman, N; Fosmire, S; Gilani, A; Green, A; Gupta, N; Hashizume, R; Hawkins, C; Hulleman, E; Jabado, N; Jones, K; Katagi, H; Lemma, R; Madhavan, K; Meel, MH; Metselaar, DS; Monje, M; Pierce, A; Sanford, B; Serkova, NJ; Sola, I; Steiner, J; Venkataraman, S; Vibhakar, R; Vijmasi, T; Wang, D | 1 |
| Arakawa, S; Hayashi, H; Ikeda, R; Kayama, T; Kurosaka, D; Marumo, K; Nagai, R; Ohno, RI; Saito, M; Suzuki, R | 1 |
| Chiba, T; Han, X; Jiang, TX; Lin, K; Luo, ZY; Ma, S; Qiu, XB; Xie, W; Zhu, QQ | 1 |
| He, Z; Hu, X; Jiang, J; Jiang, N; Li, Q; Liu, C; Liu, L; Wu, Q | 1 |
| Ikegami, S; Kato, H; Nakamura, Y; Nakano, M; Sakai, N; Suzuki, T; Takahashi, J; Tokida, R; Uehara, M | 1 |
| Canella, A; Francois, A; Marcho, LM; Stratton, MS | 1 |
| Dang, W; McCauley, BS | 1 |
| Lee, AWT; Lee, TL; Liao, J; Luk, ACS; Qi, H; Suen, HC; Yang, L | 1 |
| Adamski, J; Artati, A; Blaauw, B; Dyar, KA; Huber, S; Möller, G; Tokarz, J; Zeigerer, A | 1 |
| Fu, X; Hashimoto-Torii, K; Liu, JS; Son, AI; Suto, F; Torii, M | 1 |
| Brunet, A; Han, S; Hebestreit, K; Mair, WB; Schroeder, EA; Silva-García, CG | 1 |
| Boyd, RD; DeDecker, AE; Díaz, JAC; Foxcroft, G; Lents, CA; Phillips, CE; Prince, TJ; Stalder, KJ; Vallet, JL | 1 |
| Ritzenthaler, JD; Roman, J; Zelko, IN; Zhu, J | 1 |
| Jensen, ON; Kempf, SJ; Rogowska-Wrzesinska, A; Schwämmle, V; Tvardovskiy, A | 1 |
| Berger, MS; Cardona, AE; Cardona, SM; Huang, SA; Lemmon, VP; Lin, CA; Rhodes, CT; Zunino, G | 1 |
| Clay Bunn, R; Creecy, A; Nyman, JS; Unal, M; Uppuganti, S; Voziyan, P | 1 |
| Arnold, P; Bautmans, I; Buyl, R; Gorus, E; Njemini, R; Pool-Goudzwaard, A; Vantieghem, S | 1 |
| Ito, Y; Muramatsu, N; Nagasawa, T; Sato, T; Yamamoto, Y | 1 |
| García-Villanova, B; Guerra-Hernández, E; Hougen, HP; Márquez-Ruiz, AB; Rufián-Henares, JÁ; Valenzuela, A | 1 |
| Saito, M; Satake, Y; Takahashi, K; Takai, S | 1 |
| Bonini, NM; Kennerdell, JR; Liu, N | 1 |
| Apaydin, C; Borch Jensen, M; Davis, SS; Ghaemmaghami, S; Gibson, BW; Jasper, H; Juhasz, G; Ramanathan, A; Rodriguez-Fernandez, IA; Schilling, B; Wang, L | 1 |
| Becker, J; Eickhoff, SB; Mahlke, NS; Reckert, A; Ritz-Timme, S | 1 |
| Imai, T; Kashiwabara, S; Saito, M; Shiraki, M; Tanaka, S | 1 |
| Andrade, G; Basso, CG; Cechinel, LR; de Meireles, LCF; de Souza Grefenhagen, ÁI; Galvão, F; Lovatel, GA; Nestler, EJ; Palazzo, RP; Siqueira, IR; Walker, DM | 1 |
| Karim, L; Sroga, GE; Tang, SY; Vashishth, D | 1 |
| Michan, S | 1 |
| He, W; Hu, S; Liu, Z; Ma, G; Xu, H | 1 |
| Baloh, RH; Bouitbir, J; Dupuis, L; Eschbach, J; Fergani, A; Geny, B; Harms, MB; Larmet, Y; Loeffler, JP; Ludolph, AC; Marion, V; Messadeq, N; René, F; Schlagowski, AI; Shy, ME; Sinniger, J; Weydt, P; Zoll, J | 1 |
| Ding, X; Duan, P; Hu, G; Lin, YJ; Liu, J; Qiao, Y; Tu, P; Wu, HP; Xu, R | 1 |
| Arnold, AM; Djousse, L; Hirsch, C; Ix, JH; Kizer, JR; Mukamal, KJ; Newman, AB; Siscovick, D; Thielke, SM; Tracy, RP; Whitson, HE; Yee, LM; Zieman, S | 1 |
| Amatrudo, JM; Crimins, JL; Hof, PR; Hunt, B; Luebke, JI; Medalla, M; Peters, A; Weaver, CM | 1 |
| Baron, J; Chen, W; Cheung, CS; Lui, JC | 1 |
| Asai, K; Hirata, K; Kanazawa, H; Kyoh, S; Tochino, Y | 1 |
| Bardenheier, A; Bening-Abu-Shach, U; Boxem, M; Broday, L; Ching, K; Chou, TF; Koorman, T; Mishra, P; Podolsky, L; Sapir, A; Sternberg, PW; Tsur, A | 1 |
| Bhunia, A; Biswas, A; DiMauro, MA; Kar, RK; Nagaraj, RH; Nandi, SK; Raghavan, CT; Wang, B | 1 |
| Kim, SH; Lee, JH; Park, JY; Park, S | 1 |
| Chao, PC; Mong, MC; Yin, MC | 1 |
| Chisholm, NC; Dindot, S; Henderson, ML; Miranda, RC; Park, MJ; Selvamani, A; Sohrabji, F | 1 |
| Brecht, M; Lenschow, C | 1 |
| Auger, F; Beuscart, JB; Boulanger, E; Durieux, N; Grossin, N; Jacolot, P; Montaigne, D; Niquet-Leridon, C; Schmidt, AM; Susen, S; Tessier, FJ | 1 |
| Helfand, SL; Lee, SS; Ni, Z; Pu, M; Wang, M; Wang, X; Wood, JG; Yu, H | 1 |
| Ferrucci, L; Garcia, M; Harris, TB; Newman, AB; Satterfield, S; Schwartz, AV; Semba, RD; Sun, K; Varadhan, R | 1 |
| Asghari-Moghadam, M; Bagherzadeh Kasmani, F; Mehri, M | 1 |
| Larrick, JW; Mendelsohn, AR | 1 |
| Chun, Y; Kim, CS; Kim, HJ; Kim, J; Park, S; Song, W | 1 |
| Marumo, K; Saito, M | 1 |
| Berishvili, E; de Graaff, HJ; Fuijkschot, WW; Houtman, M; Kakabadze, Z; Krijnen, PA; Kupreishvili, K; Meinster, E; Niessen, HW; Schalkwijk, CG; Smulders, YM; van Broekhoven, A; Vonk, AB | 1 |
| Chang, JH; Cheng, X; Hu, H; Jin, J; Sun, SC; Wang, H; Xiao, Y; Xie, X; Zou, Q | 1 |
| Gius, D; O'Brien, J; Santa-Maria, CA; Zhu, Y; Zou, X | 1 |
| Chen, H; Xiao, D; Zheng, X; Zheng, Y | 1 |
| Gustienė, O; Stanislovaitienė, D; Steponavičiūtė, R; Žaliūnas, R; Žaliūnienė, D; Žemaitienė, R | 1 |
| Chovatiya, GL; Gupta, S; Khade, B; Ravi, V; Sarate, RM; Waghmare, SK | 1 |
| Bank, RA; Hooymans, JM; Los, LI; van Deemter, M; Vehof, J | 1 |
| Dankert, D; Demond, H; Eichenlaub-Ritter, U; Grümmer, R; Heiligentag, M; Horsthemke, B; Trapphoff, T | 1 |
| Ahmed, T; Baliyan, S; Balschun, D; Dotti, CG; Martin, MG; Martín-Segura, A; Palomer, E; Venero, C | 1 |
| Bendixen, C; Farajzadeh, L; Kristensen, KK; Larsen, K; Momeni, J | 1 |
| Dorca, J; Escobar, I; Llatjos, R; Machahua, C; Molina-Molina, M; Montes-Worboys, A; Vicens-Zygmunt, V | 1 |
| Gruber, J; Hagen, T; Hong, SY; Inoue, T; Ng, LF; Ng, LT; Tolwinski, NS | 1 |
| Corzo, A; Dozier, WA; Kidd, MT; Schilling, MW | 1 |
| Babusikova, E; Dobrota, D; Jesenak, M; Kaplan, P; Racay, P | 1 |
| Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP | 1 |
| Goto, S; Ishigami, A; Kawakami, K; Nakamura, A; Takahashi, R | 1 |
| Chalisova, NI; Zakutskii, AN | 1 |
| Ershler, WB; Ferrucci, L; Guralnik, JM; Longo, DL; Patel, KV; Semba, RD; Sun, K | 1 |
| Ferrucci, L; Lakatta, EG; Najjar, SS; Semba, RD; Sun, K | 1 |
| Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Semba, RD; Sun, K | 1 |
| Gao, WJ; Wang, HX | 1 |
| Bunch, TD; Fu, XW; Meng, QG; Pei, Y; Suo, L; Yan, CL; Zhu, SE | 1 |
| Bertholon, C; Chapurlat, R; Gineyts, E; Munoz, F; Sornay-Rendu, E | 1 |
| Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Guralnik, JM; Semba, RD; Sun, K; Varadhan, R; Walston, J | 1 |
| Bank, RA; Hooymans, JM; Los, LI; Ponsioen, TL; Snabel, JM; van Deemter, M; van der Worp, RJ | 1 |
| Brummer, RJ; Heitmann, BL; Nieuwenhuizen, AG; van Vught, AJ; Veldhorst, MA; Westerterp-Plantenga, MS | 1 |
| Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C | 1 |
| Branton, SL; Corzo, A; Dozier, WA; Kidd, MT; Tillman, PB | 1 |
| Bandinelli, S; Ferrucci, L; Guralnik, JM; Semba, RD; Sun, K | 1 |
| Ferrucci, L; Fink, JC; Semba, RD; Sun, K; Windham, BG | 1 |
| Fan, X; Giblin, FJ; Liu, X; Monnier, VM; Nemet, I; Qian, J; Strauch, C; Theves, M; Zhang, J | 1 |
| Tessier, FJ | 1 |
| Sweatt, JD | 1 |
| Agis-Balboa, RC; Bahari-Javan, S; Burkhardt, S; Chen, W; Cota, P; Dettenhofer, M; Farinelli, L; Fischer, A; Gogol-Doering, A; Kang, H; Opitz, L; Peleg, S; Salinas-Riester, G; Sananbenesi, F; Wittnam, JL; Zovoilis, A | 1 |
| Lima, D; Luz, LL; Safronov, BV; Szucs, P | 1 |
| Goto, S; Kametani, F; Kawakami, K; Nakamoto, H; Nakamura, A | 1 |
| Mann, M; Walther, DM | 1 |
| Dai, J; Gomes, AP; Hafner, AV; Palmeira, CM; Rosenzweig, A; Sinclair, DA; Xiao, CY | 1 |
| Asai, K; Hirata, K; Ichimaru, Y; Kanazawa, H; Kyoh, S; Tochino, Y | 1 |
| Eguchi, N; Hirohama, J; Jinno, M; Miyazaki, A; Takeuchi, M; Teruya, K; Watanabe, A | 1 |
| Anderson, HC; Crist, JD; Gardner, BM; Li, Y; Lu, Q; Rodova, M; Wang, J; Woodbury, BG; Yost, JG; Zhong, XB | 1 |
| Ali, R; Ansari, NA | 1 |
| Chow, MZ; Krishnan, V; Liu, B; Liu, X; Wang, Z; Zhang, L; Zhou, Z | 1 |
| Jurvelin, JS; Karjalainen, HM; Kokkonen, HT; Korhonen, RK; Kovanen, V; Kulmala, KA; Mäkelä, J; Rieppo, L; Tiitu, V; Töyräs, J | 1 |
| Bao, J; Lombard, DB; Tishkoff, DX | 1 |
| Cauley, JA; Harris, T; Launer, L; Lindquist, K; Rosano, C; Satterfield, S; Schwartz, AV; Simonsick, EM; Vitartas, C; Vittinghoff, E; Yaffe, K | 1 |
| Aussel, C; Cynober, L; Deutz, NE; Jourdan, M | 1 |
| Sack, MN | 1 |
| Begall, S; Dammann, P; Monnier, VM; Sell, DR; Strauch, C | 1 |
| de Boer, TN; DeGroot, J; Huisman, AM; Lafeber, FP; Mastbergen, SC; Polak, AA; Vos, PA | 1 |
| Barbanel, G; Billard, JM; Dutar, P; Haxaire, C; Kervern, M; Mothet, JP; Potier, B; Sinet, PM; Turpin, FR | 1 |
| Bandinelli, S; Ferrucci, L; Guralnik, JM; Patel, KV; Roy, CN; Semba, RD; Sun, K; Varadhan, R | 1 |
| Goto, M; Iwaki-Egawa, S; Watanabe, Y | 1 |
| Ikegami, D; Kim, YJ; Niwa, T; Takeshima, H; Ushijima, T; Wakabayashi, M | 1 |
| Caricilli, AM; Carvalheira, JB; Carvalho, BM; Carvalho-Filho, MA; Cintra, DE; Curi, R; da Silva, AS; De Souza, CT; Guadagnini, D; Hirabara, S; Katashima, CK; Pauli, JR; Ropelle, ER; Saad, MJ; Velloso, LA | 1 |
| Eda, A; Fukushima, T; Hohjoh, H; Takahashi, M | 1 |
| Black, MJ; Campbell, DJ; Jenkins, AJ; Kelly, DJ; Kenny, JF; Newcomb, AE; Prior, DL; Schalkwijk, CG; Somaratne, JB; Yii, M | 1 |
| Bertoldi, K; Cechinel, LR; Elsner, VR; Lovatel, GA; Moysés, F; Muotri, AR; Siqueira, IR; Spindler, C | 1 |
| Dei, R; Horie, K; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Washimi, Y; Watanabe, M; Yasuda, Y | 1 |
| Helliger, W; Koutzamani, E; Lindner, HH; Rundquist, I; Sarg, B | 1 |
| Horiuchi, S; Jono, T; Kimura, T; Kitamura, T; Miyazaki, K; Nagai, R; Takamatsu, J; Yuzuriha, T | 1 |
| Biemel, KM; Conrad, J; Lederer, MO | 1 |
| Corzo, A; Hoehler, D; Moran, ET | 2 |
| Gerrard, JA; Meade, SJ; Miller, AG | 1 |
| Bakala, H; Borot-Laloi, C; Friguet, B; Hamelin, M | 1 |
| Luebke, JI; Rosene, DL | 1 |
| Bakala, H; Bismuth, J; Borot-Laloi, C; Corman, B; Delaval, E; Friguet, B; Hamelin, M | 1 |
| Anderstam, B; Bárány, P; Fehrman-Ekholm, I; Heimbürger, O; Lindholm, B; Pecoits-Filho, R; Qureshi, AR; Rodríguez Ayala, E; Stenvinkel, P; Suliman, ME | 1 |
| Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F | 1 |
| Cutler, RG; Handy, A; Ingram, DK; Lane, MA; Mattison, JA; Monnier, VM; Obrenovich, ME; Roth, GS; Sell, DR | 1 |
| Frey, J; Meli, M; Perier, C | 1 |
| ALBANESE, AA; BREITENBACH, J; HIGGONS, RA; ORTO, LA; ZAVATTARO, DN | 1 |
| FORBES, RM; RAO, T | 1 |
| KAO, KY; MCGAVACK, TH | 1 |
| WALIGORA, Z; WENDER, M | 1 |
| APPELTAUER, GS; BENECH, C; FRANCHI, CM; LEVITAS, A | 1 |
| DAVIS, JR; HOLLINGER, MA; MORRIS, RN | 1 |
| Chalisova, NI; Penniiaĭnen, VA | 1 |
| Zhang, ZW | 1 |
| Boekelheide, K; Gray, DA; Rasoulpour, RJ; Schoenfeld, HA | 1 |
| Argirov, OK; Lin, B; Ortwerth, BJ | 1 |
| Ferket, P; Kogut, J; Kwakkel, R; Veldkamp, T; Verstegen, M | 1 |
| Bencko, V; Bezdícková, D; Pilin, A; Pudil, F; Sajdok, J; Zídková, J | 1 |
| Agrawal, CM; Li, X; Shen, X; Wang, X | 1 |
| Hirao, Y; Kitauchi, T; Ozono, S; Saka, T; Yoneda, T; Yoshida, K; Yoshikawa, M | 1 |
| Cruz-Sánchez, CZ; Cruz-Sánchez, FF; Gironès, X; Guimerà, A; Kalaria, R; Lafuente, JV; Makita, Z; Ortega, A; Sasaki, N | 1 |
| Applegate, TJ; Banks, KM; Rush, JK; Thompson, KL | 1 |
| Kölker, S; Müller, E | 1 |
| Kil, IS; Lee, JH; Park, JW; Shin, AH | 1 |
| Bergamini, E; Bonanomi, G; Cavallini, G; Di Stefano, R; Mosca, F; Odetti, P; Parentini, I; Poggi, A; Rossi, S | 1 |
| Monnier, VM; Obrenovich, ME | 1 |
| Chang, YM; Killiany, RJ; Luebke, JI; Mangiamele, LA; Rosene, DL | 1 |
| Amadio, L; Di Pippo, C; Iacobini, C; Menini, S; Oddi, G; Pricci, F; Pugliese, F; Pugliese, G; Ricci, C; Sorcini, M | 1 |
| Avery, NC; Bailey, AJ | 1 |
| Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T | 1 |
| Castellani, RJ; Moreira, PI; Nunomura, A; Perry, G; Smith, MA; Zhu, X | 1 |
| Schmitt, HP | 1 |
| Gill, BP | 1 |
| Degroot, J; Maroudas, A; Roughley, P; Sakkee, N; Sivan, SS; Tsitron, E; van der Ham, F; Wachtel, E | 1 |
| Asghar, M; Lokhandwala, MF | 1 |
| Stadtman, ER | 1 |
| Ahmad, G; Jamil, A; Mushtaq, T; Nisa, MU; Sarwar, M | 1 |
| Hagino, N; Ishihara, A; Kikuchi, M; Kobayashi, S; Nagai, R; Nishioka, T; Nomura, M | 1 |
| Ali, AB; Bannister, AP; Thomson, AM | 1 |
| Cai, W; Ferrucci, L; Goodman, S; Peppa, M; Striker, G; Uribarri, J; Vlassara, H | 1 |
| Czeslik, E; Friedrich, I; Gursinsky, T; Nass, N; Scheubel, RJ; Schinzel, R; Silber, RE; Simm, A; Wagner, J | 1 |
| Reinberg, D; Sternglanz, R; Vaquero, A | 1 |
| Ahmad, G; Mirza, MA; Mushtaq, MM; Mushtaq, T; Nawaz, H; Noreen, U; Sarwar, M | 1 |
| Carrithers, JA; Haus, JM; Trappe, SW; Trappe, TA | 1 |
| Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ | 1 |
| Bencko, V; Bezdícková, D; Pillin, A; Pudil, F | 1 |
| Liebert, F | 1 |
| Babušíková, E; Dobrota, D; Jeseňák, M; Kaplán, P; Tribulová, N | 1 |
| Monnier, VM; Sell, DR; Shen, W; Strauch, CM | 1 |
| Hilchey, SE; Lerner, J; Smagula, RM | 1 |
| van den Bosch de Aguilar, P; Vanneste, J | 1 |
| Robins, SP | 1 |
| Glimcher, MJ; Strawich, E | 1 |
| Graf, H; Gruhn, K | 1 |
| Bartov, I; Bengal, I; Hurwitz, S; Plavnik, I; Talpaz, H | 1 |
| Cohen, MP; Yu-Wu, V | 1 |
| Bunn, HF; Chylack, LT; Garlick, RL; Mazer, JS; Tung, WH | 1 |
| Engel, AG; Rebouche, CJ | 1 |
| Dobken, J; Siskind, GW; Weksler, ME | 1 |
| Ausman, LM; Hegsted, DM | 1 |
| Dwyer, BE; Fando, JL; Wasterlain, CG | 1 |
| Cerami, A; Monnier, VM | 1 |
| Leibholz, J; Wilson, RH | 1 |
| Burgoyne, RD; Gross, J; Rose, SP | 1 |
| Kumegawa, M; Takuma, T | 1 |
| Walz, OP | 1 |
| Hackl, W; Michelchen, G; Otto, E; Poppe, S; Wiesmüller, W | 1 |
| Cerami, A; Monnier, VM; Stevens, VJ | 1 |
| McCarthy, JP; Potter, LM; Shelton, JR | 1 |
| Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R | 1 |
| Foreman, J; Hwang, SM; Segal, S | 1 |
| Endo, F; Ishida, S; Kadono, T; Sasaki, T; Yoshinaga, K | 1 |
| Brahma, KC; Patnaik, BK | 1 |
| Funaba, M; Hawkins, RL; Inoue, M; Mori, M; Torii, K | 1 |
| Miesbauer, LR; Schwedler, J; Shun-Shin, GA; Smith, DL; Smith, JB; Sun, Y; Yang, Z; Zhou, X | 1 |
| Baynes, JW; Bell-Farrow, AD; Cefalu, WT; Fu, MX; Sonntag, WE; Thorpe, SR; Wang, ZQ | 1 |
| Easter, RA; Kerr, BJ; McKeith, FK | 1 |
| Baker, DH; Biehl, RR; Hahn, JD | 1 |
| Baynes, JW; Bichler, J; Reddy, S; Thorpe, SR; Wells-Knecht, KJ | 1 |
| Bellmunt, MJ; Cosso, L; Odetti, P; Pamplona, R; Portero, M; Prat, J | 1 |
| Aggoun-Zouaoui, D; Innocenti, GM | 1 |
| McDonald, R; McGee, C; Reiser, K; Rucker, R | 1 |
| Boja, B; Monnier, V; Moskowitz, RW; Pokharna, HK | 1 |
| Reiser, KM | 1 |
| Höger, H; Lubec, B; Lubec, G; Radner, W; Salzer, H | 1 |
| Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A | 1 |
| Carlson, EC; Monnier, VM; Sell, DR | 1 |
| Monnier, V | 1 |
| Blackman, MR; Corpas, E; Harman, SM; Roberson, R; Scholfield, D | 1 |
| Behar, KL; Ogino, T | 1 |
| Bruce, LL | 1 |
| Denda, M; Horiuchi, K; Inoue, T; Ishihara, C; Kawana, K; Kushida, K; Takahashi, M | 1 |
| Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Cutler, RG; Fogarty, JF; Ingram, DK; Johnson, WA; Lane, MA; Masoro, EJ; Mock, OB; Monnier, VM; Reiser, KM; Roth, GS; Sell, DR | 1 |
| Brumm, MC; Dahlquist, JM; Shelton, DP | 1 |
| Coffey, RD; Cromwell, GL | 1 |
| Apgar, GA; Kornegay, ET; Lindemann, MD; Notter, DR | 1 |
| Carrion, D; Coma, J; Zimmerman, DR | 1 |
| Dritz, SS; Goodband, RD; Nelssen, JL; Owen, KQ; Tokach, MD | 1 |
| Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Takahashi, M | 1 |
| Chagneau, AM; Maaa, N; Peresson, R; Tesseraud, S | 1 |
| Bailey, AJ; Oxlund, H; Rasmussen, LM; Sims, TJ | 1 |
| Coffey, MT; Spears, JW; van Heugten, E | 1 |
| Cosso, L; Marinari, UM; Noberasco, G; Odetti, P; Pronzato, MA; Traverso, N | 1 |
| Gengin, MT; Shchetinina, NV; Vernigora, AN | 1 |
| Nerlich, AG; Schleicher, ED; Wagner, E | 1 |
| Bailey, AJ; Paul, RG | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV | 1 |
| England, JA; Mendes, AA; Saleh, EA; Waldroup, AL; Waldroup, PW; Watkins, SE | 1 |
| Anthony, NB; Kerr, BJ; Kidd, MT | 1 |
| Cruz, W; Fogarty, J; Hampel, N; Jiaan, DB; Monnier, VM; Pomerantz, J; Seftel, AD; Zuik, M | 1 |
| Sell, DR | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann Frye, E; Degenhardt, TP; Thorpe, SR | 1 |
| Ducro, BJ; Kwakkel, RP; Verstegen, MW | 1 |
| Abe, M; Funaba, M; Iriki, T | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, T; Sobue, G; Takeda, A; Yasuda, T; Yasuda, Y | 1 |
| Monnier, VM; Sell, DR | 2 |
| Douglas, MW; Johnson, ML; Parsons, CM | 1 |
| Iqbal, M; Klandorf, H; Probert, LL | 1 |
| Fujii, K; Ishioka, N; Marumo, K; Saito, M | 1 |
| Bergström, JR; Dritz, SS; Goodband, RD; Nelssen, JL; Nessmith, WB; Richert, BT; Tokach, MD | 1 |
| Boos, N; Nerlich, AG; Schleicher, ED | 1 |
| Boeri, D; Maiello, M; Marinari, UM; Odetti, P; Pronzato, MA; Sampietro, L | 1 |
| Bank, RA; Bayliss, MT; Lafeber, FP; Maroudas, A; Tekoppele, JM | 1 |
| Higami, Y; Horiuchi, S; Ikeda, T; Iwasaki, M; Shimokawa, I | 1 |
| Pokharna, HK; Pottenger, LA | 1 |
| Bailey, AJ; Knott, L | 1 |
| Sharpe, NA; Tepper, JM | 1 |
| Aragno, I; Garibaldi, S; Odetti, P; Pronzato, MA; Rolandi, R; Valentini, S | 1 |
| Baynes, JW; Degenhardt, TP; Frye, EB; Thorpe, SR | 1 |
| Phillips, FM; Pokharna, HK | 1 |
| Horiuchi, S; Kimura, T; Miyakawa, T; Miyata, T; Takamatsu, J | 1 |
| Burnham, DJ; Cantor, AH; Ferguson, NS; Ford, MJ; Gates, RS; Pescatore, AJ; Taraba, JL | 1 |
| Kanai, M; Nagata, M; Nagayama, Y; Nakamura, K; Saito, N; Takahashi, S; Yoshihara, K | 1 |
| Akyol, M; Bell, J; Briggs, JD; Dominiczak, MH; Shaw, S | 1 |
| Baynes, JW; Degenhardt, TP; Thorpe, SR | 1 |
| Avery, N; Crean, JK; Duance, VC; Eisenstein, SM; Menage, J; Roberts, S; Sims, TJ; Smith, S | 1 |
| Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Aotaki-Keen, A; Handa, JT; Hjelmeland, LM; Lutty, GA; Matsunaga, H; Miyata, T; te Koppele, JM; Verzijl, N | 1 |
| Bass, AH; Knapp, R; Marchaterre, MA | 1 |
| Alhumadi, NH; Iqbal, M; Klandorf, H; Probert, LL | 1 |
| Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N | 1 |
| Bank, RA; Hazleman, BL; Oostingh, G; Riley, GP; TeKoppele, JM | 1 |
| Bao, M; Li, D; Li, YM; Song, X | 1 |
| Aotaki-Keen, A; Farboud, B; Handa, JT; Hjelmeland, LM; Miyata, T | 1 |
| Monnier, VM; Obrenovich, M; Tessier, F | 1 |
| Requena, JR; Stadtman, ER | 1 |
| Ben-Ari, Y; Chevassus-Au-Louis, N; Diabira, D; Gozlan, H; Hennou, S | 1 |
| Baynes, JW; Litchfield, JE; Thorpe, SR | 1 |
| Aamodt, SM; Colonnese, MT; Constantine-Paton, M; Shi, J; Veras, W | 1 |
| Nagano, A; Oikawa, M; Takahashi, M | 1 |
| Lingelbach, LB; McDonald, RB; Mitchell, AE; Rucker, RB | 1 |
| Brownson, C; Hipkiss, AR | 1 |
| Hayase, K; Koie, M; Tanaka, M; Yokogoshi, H | 1 |
| Bank, RA; Bayliss, MT; Baynes, JW; Bijlsma, JW; DeGroot, J; Lafeber, FP; Oldehinkel, E; Tekoppele, JM; Thorpe, SR; Verzijl, N | 1 |
| Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C | 1 |
| Brannon, JA; Carlson, CW; Noll, SL; Waibel, PE | 1 |
| Al-Humadi, NH; Iqbal, M; Kenney, PB; Klandorf, H | 1 |
| Ferket, PR; Kwakkel, RP; Nixey, C; Noordhuizen, JP; Veldkamp, T | 1 |
| Buddington, RK; Elnif, J; Malo, C; Sangild, PT | 1 |
| Fedele, D; Lapolla, A; Traldi, P | 1 |
| Austic, RE; Park, BC | 1 |
| Dei, R; Goto, Y; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Watanabe, M; Yamamoto, M; Yasuda, T; Yasuda, Y | 1 |
| Lu, L; Thompson, JE; Wang, D; Wang, TW | 1 |
| Stryker, MP; Trachtenberg, JT | 1 |
| Iqbal, M; Klandorf, H; Rathore, DS; Shi, X; Van Dyke, K | 1 |
| Brown, TH; McGann, JP; Moyer, JR | 1 |
| Aniksztejn, L; Ben-Ari, Y; Demarque, M; Morozov, Y; Represa, A | 1 |
| Donabedian, M; Hare, JM; Rosas, GO; Vandegaer, K; Zieman, SJ | 1 |
| Bank, RA; Bayliss, MT; Bijlsma, JW; DeGroot, J; Lafeber, FP; Maroudas, A; TeKoppele, JM; Verzijl, N | 1 |
| Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N; Wenting-Van Wijk, MJ | 1 |
| Cobden, PM; Cope, DW; Maccaferri, G; Márton, LF; Roberts, JD; Somogyi, P | 1 |
| Choy, HE; Kim, JH; Nam, KH; Park, SC | 1 |
| Bank, RA; Baynes, JW; Ben, ZC; Bijlsma, JW; Brau-Benjamin, O; DeGroot, J; Lafeber, FP; Maroudas, A; Mizrahi, J; Schalkwijk, CG; TeKoppele, JM; Thorpe, SR; Verzijl, N | 1 |
| Bottjer, SW; Iyengar, S | 1 |
| Arai, K; Chikuda, M; Matsumoto, Y; Takahashi, M | 1 |
| Faist, V; Heidland, A; Klvanová, J; Krajcoviová-Kudlácková, M; Schinzel, R; Sebeková, K | 1 |
| Barja, G; Bellmun, MJ; Gredilla, R; Pamplona, R; Portero-Otín, M | 1 |
| Calvert, CC; Larsen, JA; Rogers, QR | 1 |
| Borrell, V; del Río, JA; Martínez, A; Solé, M; Soriano, E | 1 |
| Ali, M; Ruiz-Torres, A | 1 |
| Campagnoni, AT; Campagnoni, CW; Carey, GD | 1 |
| Daniels, VG; Murphy, S | 1 |
| Courtois, Y; Moczar, M; Ouzilou, J; Robert, L | 1 |
| Allard, R; Bouissou, H; Julian, M; Moczar, M; Ouzilou, J; Pieraggi, MT; Robert, L | 1 |
| Robert, AM; Robert, L | 1 |
| Ackley, S; Ho, RW; Lawrence, AE; Mays, LL | 1 |
| Hwang, SM; Segal, S | 1 |
| Brickley-Parsons, D; Glimcher, MJ; Shapiro, F | 1 |
| Weintraub, H | 1 |
| Deyl, Z; Helm, R; Vancikova, O | 1 |
| Hoyer, JR; Spiro, RG | 1 |
| Miyahara, T; Murai, A; Shiozawa, S | 1 |
| Castellani, I; Giro, MG; Peserico, A; Volpin, D | 1 |
| Fujii, K; Kuboki, Y; Sasaki, S | 1 |
| Bernikov, VA; Gorel', FL; Sharypov, VF | 1 |
| Jin, ZL; Lee, TF; Wang, LC | 1 |
| Arnal, M; Obled, C | 1 |
| Chang, YF; Pan, X; Rao, VV | 1 |
| Katsumaru, H; Murakami, F; Okawa, K; Saito, Y; Shimono, K; Song, WJ | 1 |
| Grandhee, S; Ibrahim, SA; Miyata, S; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR | 1 |
| Fujie, M; Horiuchi, K; Inoue, T; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A | 1 |
| Fogarty, J; Grandhee, SK; Lapolla, A; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR | 1 |
| Baynes, JW; Dunn, JA; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Baynes, JW; Dunn, JA; Knecht, KJ; Lyons, TJ; McCance, DR; McFarland, KF; Thorpe, SR | 1 |
| Deyl, Z; Miksík, I | 1 |
| Deyl, Z; Miksik, I; Struzinsky, R | 1 |
| Menzel, EJ; Reihsner, R | 1 |
| Eyre, DR; Hormel, SE | 1 |
| Prasad, S; Thakur, MK | 1 |
| Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M; Sell, DR | 1 |
| Beardsworth, LJ; Dickson, IR; Eyre, DR | 1 |
| Baba, S; Hata, F; Igaki, N; Kitamura, Y; Maeda, S; Nishimoto, S; Oimomi, M | 1 |
| Pensa, M; Rinaldi, E; Simonelli, F | 1 |
| Baba, S; Nishimoto, S; Oimomi, M | 1 |
| Arai, K; Iizuka, S; Kinoshita, N; Naito, T; Taniquchi, N; Usui, M | 1 |
| Ayala, A; Bautista, J; Gordillo, E; Machado, A | 1 |
| Baynes, JW; Dunn, JA; Patrick, JS; Thorpe, SR | 1 |
| Baba, S; Hata, F; Hatanaka, H; Kitamura, Y; Maeda, Y; Matsumoto, S; Oimomi, M | 1 |
| Wilson, RP | 1 |
| Baba, S; Hatanaka, H; Kitamura, Y; Matsumoto, S; Nishimoto, S; Oimomi, M | 1 |
| Fabris, N; Mocchegiani, E; Muzzioli, M; Piloni, S | 1 |
| Olson, AL; Rebouche, CJ | 1 |
| Bailey, AJ; Barnard, K; Light, ND; Sims, TJ | 1 |
| Mechanic, GL; Woodley, DT; Yamauchi, M | 1 |
| Ayala, A; Bautista, J; F-Lobato, M; Gordillo, E; Machado, A | 1 |
| Kato, H; Naito, H; Nam, TJ; Noguchi, T | 1 |
| Baba, S; Hata, F; Hatanaka, H; Kitamura, Y; Maeda, Y; Masuta, S; Matsumoto, S; Nakamichi, T; Nishimoto, S; Oimomi, M | 1 |
| Hata, F; Igaki, N; Kitamura, Y; Maeda, Y; Masuta, S; Matsumoto, S; Nakamichi, T; Nishimoto, S; Oohara, T; Sakai, M | 1 |
| Ricard-Blum, S; Ville, G | 1 |
| Auray-Blais, C; Clow, CL; Giguère, R; Goodyer, P; Lemieux, B; Reade, TM; Scriver, CR | 1 |
| Cree, TC; Schalch, DS | 1 |
| Bone, AH; Davison, AN; Sabri, MI | 1 |
| Al-Sarraf, M; Belamaric, J; Cejka, J; Kithier, K; Peterson, WD; Poulik, MD; Vaitkevicius, VK | 1 |
| Kadar, A; Robert, B; Robert, L | 1 |
| Liu, LP; Ortwerth, BJ | 1 |
| Mezei, C; Palmer, FB | 1 |
| Dunlop, DS; Lajtha, A; Van Elden, W | 1 |
| Duerre, JA; Lee, CT | 1 |
| Lovenberg, W; Yamabe, H | 1 |
| Kim, S; Paik, WK | 3 |
| Pénzes, L | 2 |
| Bailey, AJ; Fowler, LJ | 1 |
| Igo-Kemenes, T; Spadafora, C; Zachau, HG | 1 |
| Porembska, Z | 1 |
| Azzola, S; Comolli, R; Ferioli, ME | 1 |
| Benditt, M; Kim, S; Paik, WK | 1 |
| Anttinen, H; Kivirikko, KI; Orava, S; Ryhänen, L | 1 |
| Seyer, JM; Vinson, WC | 1 |
| Ebel, A; Fontaine, R; Mack, G | 1 |
| Bornstein, P | 1 |
| Eichhorn, GL; Miller, J; von Hahn, HP | 1 |
| Deshmukh, A; Deshmukh, K; Nimni, ME | 1 |
| Lavinha, F; Lowenthal, A; Mardens, Y; Van Regemorter, N; Van Sande, M | 1 |
| Bailey, AJ; Robins, SP | 1 |
| Acharya, PV | 1 |
| Derouette, S; Moczar, E; Robert, L | 1 |
| Bowman, R; Sobel, H | 2 |
| Elsas, LJ; MacDonell, RC; Rosenberg, LE | 1 |
| Legrand, Y; Pignaud, G | 1 |
| Graeber, W | 1 |
| Costello, R; Dubos, R; Schaedler, RW | 1 |
| Chalkley, R; Panyim, S | 1 |
| Jackson, DS | 1 |
| Rohlfing, DL | 1 |
| Levi, G | 1 |
| Dixon, GH; Ling, V | 1 |
| Akazawa, S; Matsuoka, Y; Nakajima, T | 1 |
| Krishna, I; Levenbook, L | 1 |
| Spiro, MJ; Spiro, RG | 1 |
| Albrecht, I; Elsas, LJ; Rosenberg, LE | 1 |
| Pyhtilä, MJ; Sherman, FG | 1 |
| Fukushi, S; Spiro, RG | 1 |
| Segal, S; Smith, I | 1 |
| Duruy, A | 1 |
| Fritz, RR; Rappoport, DA; Yamagami, S | 1 |
| Kodirov, AN; Korot'ko, GF | 1 |
36 review(s) available for lysine and Aging
| Article | Year |
|---|---|
Uncovering Robust Delactoylase and Depyruvoylase Activities of HDAC Isoforms.
Topics: Aging; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Protein Isoforms; Repressor Proteins; Sirtuin 2; Zinc | 2022 |
Unique molecular networks: Formation and role of elastin cross-links.
Topics: 2-Aminoadipic Acid; Aging; Animals; Blood Vessels; Connective Tissue Diseases; Elastic Tissue; Elastin; Humans; Ligaments; Lung; Lysine; Microfibrils; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Skin | 2020 |
Protein acetylation in cardiac aging.
Topics: Acetylation; Aging; Animals; Biomarkers; Cell Nucleus; Cytoplasm; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation; Heart; Histone Deacetylases; Humans; Lysine; Mitochondria, Heart; Myocardium; Protein Processing, Post-Translational; Sarcomeres | 2021 |
Acetylome regulation by sirtuins in the brain: from normal physiology to aging and pathology.
Topics: Acetylation; Aging; Animals; Autophagy; Brain; Brain Neoplasms; Cellular Senescence; Circadian Rhythm; DNA Damage; Emotions; Humans; Lysine; Neurodegenerative Diseases; Neurogenesis; NF-kappa B; Oxidative Stress; Proteome; Sirtuins | 2013 |
Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.
Topics: Aging; Animals; Biomarkers; Chromobox Protein Homolog 5; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Stem Cells | 2015 |
[Determinants of bone quality and strength independent of bone remodeling].
Topics: Aging; Animals; Arginine; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Collagen; Diphosphonates; Female; Fractures, Stress; Glucocorticoids; Glycation End Products, Advanced; Humans; Lysine; Male; Osteoporosis; Precision Medicine; Selective Estrogen Receptor Modulators | 2016 |
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.
Topics: Acetylation; Aging; Biomarkers, Tumor; Breast Neoplasms; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Incidence; Longevity; Lysine; Molecular Targeted Therapy; Neoplasm Metastasis; Phenotype; Recurrence; Sirtuin 3; Superoxide Dismutase | 2016 |
The Maillard reaction in the human body. The main discoveries and factors that affect glycation.
Topics: Aging; Amino Acids; Diabetes Mellitus; Extracellular Matrix; Food; Free Radicals; Glucose; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Monosaccharides; Oxidation-Reduction; Protein Carbonylation; Proteins; Receptor for Advanced Glycation End Products | 2010 |
Biological significance of protein modifications in aging and calorie restriction.
Topics: Acetylation; Aging; Animals; Caloric Restriction; Histones; Lysine; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proteomics; Rats; Serine | 2010 |
Glycated lysine residues: a marker for non-enzymatic protein glycation in age-related diseases.
Topics: Aging; Animals; Arthritis; Autoantibodies; Biomarkers; Diabetes Mellitus; Glycoproteins; Glycosylation; Humans; Lysine | 2011 |
Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation.
Topics: Acetylation; Adaptation, Physiological; Aging; Animals; Energy Metabolism; Homeostasis; Humans; Lysine; Mitochondria; Mitochondrial Proteins; Phenotype; Protein Processing, Post-Translational; Sirtuins | 2011 |
The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging.
Topics: Acetylation; Adaptation, Physiological; Aging; Animals; Cardiomegaly; Enzyme Activation; Homeostasis; Humans; Lysine; Mitochondria, Heart; Mitochondrial Proteins; Sirtuin 3 | 2012 |
Native protein glycoxidation and aging.
Topics: Aging; Arginine; Carbohydrate Metabolism; Free Radicals; Glucose; Glycation End Products, Advanced; Glycosylation; Half-Life; Humans; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins | 2003 |
[Age-related post-translational modification of proteins in human tissue and its use determination of age in forensic medicine. Review].
Topics: Aging; Arginine; Forensic Medicine; Glycation End Products, Advanced; Humans; Lysine; Protein Processing, Post-Translational | 2003 |
Reduction of lysine intake while avoiding malnutrition--major goals and major problems in dietary treatment of glutaryl-CoA dehydrogenase deficiency.
Topics: Adult; Aging; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Diet, Protein-Restricted; Glutaryl-CoA Dehydrogenase; Humans; Infant; Lysine; Malnutrition; Oxidoreductases Acting on CH-CH Group Donors | 2004 |
Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts.
Topics: Aging; Animals; Apoptosis; Cell Cycle; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Lysine; Maillard Reaction; Models, Biological; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction | 2005 |
Oxidative stress and neurodegeneration.
Topics: Aging; Alzheimer Disease; Glycation End Products, Advanced; Humans; Lysine; Nerve Degeneration; Oxidative Stress | 2005 |
Protein oxidation and aging.
Topics: Aging; Amino Acids; Animals; Cross-Linking Reagents; Humans; Lysine; Methionine; Oxidation-Reduction; Proteins; Reactive Oxygen Species | 2006 |
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs.
Topics: Acetylation; Aging; Diabetes Mellitus; Histone Deacetylases; Histones; Humans; Lysine; NAD; Neoplasms; Sirtuins | 2007 |
Analysis of the crosslinking components in collagen and elastin.
Topics: Aging; Amino Acids; Animals; Bone and Bones; Borohydrides; Buffers; Cartilage; Chemical Fractionation; Chemical Phenomena; Chemistry; Chromatography; Collagen; Cyanides; Drug Stability; Elastin; Glycosides; Hexoses; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylysine; Lysine; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Schiff Bases; Skin | 1982 |
Maillard reactions involving proteins and carbohydrates in vivo: relevance to diabetes mellitus and aging.
Topics: Aging; Animals; Blood Proteins; Carbohydrate Metabolism; Collagen; Crystallins; Diabetes Mellitus; Elastin; Glucose; Glycated Hemoglobin; Glycolysis; Hot Temperature; Humans; Lysine; Models, Biological; Proteins | 1981 |
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lysine; Maillard Reaction; Renal Insufficiency | 1993 |
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles | 1996 |
New biomarkers of Maillard reaction damage to proteins.
Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles | 1996 |
Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance.
Topics: Aging; Amino Acids; Animals; Bone and Bones; Bone Development; Calcification, Physiologic; Collagen; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteoporosis; Protein-Lysine 6-Oxidase | 1998 |
AGE in micro- and macroangiopathy.
Topics: Aging; Animals; Arginine; Arteriosclerosis; Cell Adhesion; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Interferon-gamma; Lysine; Membrane Proteins; Microcirculation; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; T-Lymphocytes; Vascular Diseases | 2001 |
Transglutaminase-mediated crosslinking of specific core histone subunits and cellular senescence.
Topics: Aging; Animals; Brain; Cell Nucleus; Cells, Cultured; Cellular Senescence; Cross-Linking Reagents; Cytoplasm; Fibroblasts; Glutamine; Histones; Humans; Isoenzymes; Liver; Lysine; Macromolecular Substances; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Phenotype; Protein Subunits; Rats; Rats, Sprague-Dawley; Transglutaminases | 2001 |
Pathophysiology of the intercellular matrix as a whole.
Topics: Aging; Animals; Aorta; Arteriosclerosis; Autoantibodies; Connective Tissue; Elastin; Glucosamine; Glycoproteins; Humans; Lipid Metabolism; Lysine | 1977 |
Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia.
Topics: Aging; Arginine; Diabetes Mellitus; Extracellular Matrix Proteins; Humans; Lysine; Maillard Reaction; Proteins; Uremia | 1992 |
Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia.
Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Cross-Linking Reagents; Diabetes Mellitus; Dura Mater; Humans; Lysine; Uremia | 1991 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
Collagen cross-linking.
Topics: Aging; Animals; Collagen; Connective Tissue; Humans; Lysine; Molecular Structure | 1988 |
The macromolecules of the intercellular matrix of the arterial wall: collagen, elastin, proteoglycans, and glycoproteins.
Topics: Age Factors; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Radioisotopes; Chickens; Collagen; Connective Tissue; Connective Tissue Cells; Elastin; Endothelium; Female; Glycoproteins; Glycosaminoglycans; Humans; Hydroxyproline; Hypertension; In Vitro Techniques; Lysine; Male; Microscopy, Electron; Muscle, Smooth; Proline; Rabbits; Rats; Swine | 1974 |
Current concepts of the crosslinking in bone collagen.
Topics: Aging; Animals; Bone and Bones; Bone Matrix; Borohydrides; Cartilage; Cattle; Chickens; Chromatography, Ion Exchange; Collagen; Decalcification Technique; Hydro-Lyases; Hydroxylysine; Lysine; Radioisotopes; Solubility; Tendons; Tritium; Tropocollagen | 1972 |
Different species of arginase in animal tissues.
Topics: Aging; Animals; Anura; Arginase; Brain; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Drug Stability; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Humans; Isoenzymes; Kidney; Kinetics; Liver; Lysine; Molecular Weight; Organ Specificity; Ornithine; Rats; Species Specificity; Submandibular Gland; Sulfhydryl Reagents; Time Factors | 1973 |
The cross-linking of collagen and elastin and its inhibition in osteolathyrism. Is there a relation to the aging process?
Topics: Aging; Aldehydes; Animals; Bone Diseases; Collagen; Connective Tissue; Elastin; Lathyrism; Lysine; Peptide Biosynthesis; Pyridinium Compounds | 1970 |
11 trial(s) available for lysine and Aging
| Article | Year |
|---|---|
Effect of dietary digestible lysine level on growth performance, blood metabolites and meat quality of broilers 23-38 days of age.
Topics: Aging; Animals; Chickens; Lysine; Male; Meat | 2020 |
Effect of feeding three lysine to energy diets on growth, body composition and age at puberty in replacement gilts.
Topics: Aging; Animals; Body Composition; Coronavirus Infections; Female; Lysine; Porcine epidemic diarrhea virus; Sexual Maturation; Swine; Swine Diseases | 2017 |
Dietary digestible lysine requirements of male and female broilers from forty-nine to sixty-three days of age.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Dose-Response Relationship, Drug; Female; Lysine; Male; Nutritional Requirements; Sex Characteristics; Weight Gain | 2008 |
Digestible lysine requirements of male and female broilers from fourteen to twenty-eight days of age.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Dose-Response Relationship, Drug; Female; Lysine; Male; Nutritional Requirements | 2009 |
Body composition of breeding gilts in response to dietary protein and energy balance from thirty kilograms of body weight to completion of first parity.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Diet; Dietary Proteins; Dose-Response Relationship, Drug; Energy Metabolism; Feeding Behavior; Female; Litter Size; Lysine; Parity; Pregnancy; Swine; Weight Gain | 2006 |
The influence of exogenous multienzyme preparation and graded levels of digestible lysine in sunflower meal-based diets on the performance of young broiler chicks two weeks posthatching.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Digestion; Helianthus; Lysine; Multienzyme Complexes | 2006 |
Influence of canola meal-based diets supplemented with exogenous enzyme and digestible lysine on performance, digestibility, carcass, and immunity responses of broiler chickens.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Brassica napus; Chickens; Diet; Digestion; Lysine; Male | 2007 |
Modelling the optimal lysine to threonine ratio in growing chickens depending on age and efficiency of dietary amino acid utilisation.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Proteins; Lysine; Male; Models, Biological; Nutritional Requirements; Threonine; Weight Gain | 2008 |
Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men.
Topics: Administration, Oral; Adult; Aged; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Lysine; Male; Middle Aged | 1993 |
The effect of dietary methionine and its relationship to lysine on growth performance of the segregated early-weaned pig.
Topics: Aging; Animals; Cystine; Diet; Lysine; Methionine; Swine; Weaning | 1995 |
Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens.
Topics: Aging; Animals; Arginine; Biomechanical Phenomena; Chickens; Diet; Elasticity; Female; Food Deprivation; Guanidines; Lysine; Regression Analysis; Tendons; Tensile Strength | 2000 |
367 other study(ies) available for lysine and Aging
| Article | Year |
|---|---|
[Proteome and Acetylome Profiling of Livers in C57BL/6J Male Mice during Normal Aging].
Topics: Acetylation; Aging; Animals; Liver; Lysine; Male; Mice; Mice, Inbred C57BL; Proteome | 2021 |
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
Topics: Aging; Animals; Cell Line; Cell Proliferation; Endothelial Cells; Glycosylation; Glyoxal; Humans; Lysine; Methylation; Mice; Mice, Inbred C57BL; Microtubules; Primary Cell Culture; Protein Processing, Post-Translational; Proteins; Proteomics; Proteostasis; Tubulin | 2021 |
GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression.
Topics: Acetylation; Aging; Animals; DNA; Dystrophin; Gene Expression Regulation; Humans; Lysine; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Fibers, Skeletal; Muscles; Muscular Atrophy; Muscular Dystrophies; p300-CBP Transcription Factors; Transcriptome; YY1 Transcription Factor | 2022 |
Age-related neuronal damage by advanced glycation end products through altered proteostasis.
Topics: Aging; Animals; Autophagy-Related Protein 5; bcl-2-Associated X Protein; Brain; Brain-Derived Neurotrophic Factor; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Lysine; Neurons; Proteostasis; Pyruvaldehyde; Rats; Rats, Wistar; Ubiquitin; Unfolded Protein Response | 2022 |
Aging-accelerated differential production and aggregation of STAT3 protein in neuronal cells and neural stem cells in the male mouse spinal cord.
Topics: Aging; Animals; Lysine; Male; Mice; Neural Stem Cells; Protein Aggregates; Spinal Cord; STAT3 Transcription Factor; Ubiquitins | 2023 |
The emerging role of lysine succinylation in ovarian aging.
Topics: Aging; Animals; Female; Follicular Atresia; Humans; Lysine; Mice; Primary Ovarian Insufficiency | 2023 |
Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice.
Topics: Aged; Aging; Animals; Histones; Humans; Infant; Lysine; Mice; Protein Processing, Post-Translational; Proteomics | 2023 |
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.
Topics: Adult; Aging; Biological Clocks; CpG Islands; DNA Methylation; Entropy; Epigenesis, Genetic; Genetic Testing; Genome, Human; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Lysine; Models, Genetic; Sotos Syndrome | 2019 |
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; tau Proteins | 2019 |
Lysine malonylation and propionylation are prevalent in human lens proteins.
Topics: Aging; Animals; Blotting, Western; Chromatography, Liquid; Crystallins; Cytoskeletal Proteins; Cytosol; Epithelial Cells; Humans; Immunohistochemistry; Lens, Crystalline; Lysine; Malonates; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitochondrial Proteins; Organ Culture Techniques; Paraffin Embedding; Propionates; Sirtuin 3; Sirtuins; Tandem Mass Spectrometry | 2020 |
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan | 2020 |
Pre-Exposure to Nicotine with Nocturnal Abstinence Induces Epigenetic Changes that Potentiate Nicotine Preference.
Topics: Acetylation; Aging; Animals; Behavior, Animal; Brain; Circadian Rhythm; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Lysine; Nicotine; Phenylbutyrates; Phosphorylation; Protein Subunits; Receptors, Nicotinic; Reward; RNA, Messenger; Task Performance and Analysis; Zebrafish | 2020 |
Histone H3K9 methylation is involved in temporomandibular joint osteoarthritis.
Topics: Aging; Animals; Apoptosis; Cell Proliferation; Female; Histones; Lysine; Methylation; Mice; Mice, Inbred C57BL; Osteoarthritis; Temporomandibular Joint | 2020 |
Two conserved epigenetic regulators prevent healthy ageing.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cognition; Cognitive Dysfunction; Epigenesis, Genetic; Healthy Aging; Histone-Lysine N-Methyltransferase; Histones; Humans; Longevity; Lysine; Male; Memory; Methylation; Mice; Mitochondria; Neurons; Proteins; RNA Interference; Spatial Learning; Transcription Factors, General | 2020 |
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration.
Topics: Aging; Animals; Carcinogenesis; CCAAT-Enhancer-Binding Proteins; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA Replication; Genome, Human; HeLa Cells; Histones; Humans; Inheritance Patterns; Kinetics; Lysine; Mice; Mitosis; Mouse Embryonic Stem Cells; Nucleosomes; Proliferating Cell Nuclear Antigen; Protein Binding; Protein Domains; Ubiquitin-Protein Ligases | 2020 |
Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging.
Topics: Aging; Animals; Cell Line; Cellular Senescence; Humans; Hydrogen Peroxide; Lysine; Monoamine Oxidase; Mutation; Myoblasts, Cardiac; Myocardium; Protein Engineering; Rats | 2020 |
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Topics: Aging; Astrocytoma; Brain Stem Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Chromatin; Diffuse Intrinsic Pontine Glioma; Epigenomics; Female; Glioma; Histones; Humans; Lysine; Male; Mutation; Neoplasm Recurrence, Local; Polycomb Repressive Complex 1 | 2020 |
Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Bone and Bones; Bone Diseases; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Mass Spectrometry; Ornithine; Sex Characteristics; Tartrate-Resistant Acid Phosphatase | 2020 |
Proteasome activator PA200 maintains stability of histone marks during transcription and aging.
Topics: Acetylation; Aging; Animals; Histone Code; Histones; Lysine; Mice; Nuclear Proteins; Proteasome Endopeptidase Complex; Transcription, Genetic | 2021 |
Age-related changes in expression of lysine48 and lysine63 ubiquitin linkages in dopamine neurons of midbrain in mice.
Topics: Age Factors; Aging; Animals; Dopaminergic Neurons; Lysine; Mesencephalon; Mice; Ubiquitin; Ubiquitination | 2021 |
Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry.
Topics: Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Arginine; Biomarkers; Bone Density; Bone Resorption; Cohort Studies; Female; Femur Neck; Hip; Humans; Japan; Lysine; Male; Middle Aged; Osteoporosis; Reference Values; Registries; Tartrate-Resistant Acid Phosphatase; Vitamin D | 2021 |
Loosening chromatin and dysregulated transcription: a perspective on cryptic transcription during mammalian aging.
Topics: Aging; Animals; Chromatin; DNA-Binding Proteins; Histones; Lysine; Mammals; Saccharomyces cerevisiae; Transcription, Genetic | 2022 |
Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation.
Topics: 5-Methylcytosine; Adult Germline Stem Cells; Aging; Alternative Splicing; Animals; Cell Differentiation; Epigenome; Gene Expression Profiling; Gene Expression Regulation; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; RNA, Long Noncoding; Testis | 2021 |
Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging.
Topics: Aging; Animals; Arginine; Lysine; Male; Mice; Muscle, Skeletal; Oxidative Stress; Signal Transduction | 2021 |
Proteome dynamics during postnatal mouse corpus callosum development.
Topics: Aging; Animals; Animals, Newborn; Cluster Analysis; Corpus Callosum; Isotope Labeling; Lysine; Mass Spectrometry; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Proteome; Receptors, Cell Surface; RNA Interference; RNA, Small Interfering | 2017 |
Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
Topics: Aging; Animals; Caenorhabditis elegans; Dietary Fats; Down-Regulation; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Germ Cells; Histone-Lysine N-Methyltransferase; Histones; Intestinal Mucosa; Intestines; Lipid Metabolism; Longevity; Lysine; Methylation; Ribosomal Protein S6 Kinases, 70-kDa; Stearoyl-CoA Desaturase; Up-Regulation | 2017 |
Epigenetic regulation of EC-SOD expression in aging lung fibroblasts: Role of histone acetylation.
Topics: Acetylation; Aging; Animals; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Histone Deacetylase Inhibitors; Histones; Lung; Lysine; Mice; Mice, Inbred C57BL; Primary Cell Culture; Promoter Regions, Genetic; Protein Isoforms; Protein Processing, Post-Translational; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
Accumulation of histone variant H3.3 with age is associated with profound changes in the histone methylation landscape.
Topics: Aging; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Hepatocytes; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice, Inbred C57BL; Protein Isoforms; Protein Processing, Post-Translational | 2017 |
Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches.
Topics: Aging; Animals; Cell Differentiation; Cell Movement; Chromatin; Enhancer of Zeste Homolog 2 Protein; Gene Knockout Techniques; Histone-Lysine N-Methyltransferase; Histones; Homologous Recombination; Integrases; Lysine; Methylation; Mice; Neurogenesis; Neurons; Organ Specificity; Recombinant Proteins; S Phase | 2018 |
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
Topics: Aging; Animals; Arginine; Bone Density; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Femur; Fractures, Bone; Lysine; Male; Mice; Spectrum Analysis, Raman; X-Ray Microtomography | 2018 |
Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Electromyography; Female; Glycation End Products, Advanced; Humans; Inflammation; Isometric Contraction; Linear Models; Lysine; Male; Muscle Weakness; Muscle, Skeletal; Reaction Time; Sarcopenia; Sex Factors | 2018 |
L-Lysine Attenuates Hepatic Steatosis in Senescence-Accelerated Mouse Prone 8 Mice.
Topics: Aging; Alanine Transaminase; Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Cholesterol; Diet; Dietary Supplements; Disease Models, Animal; Liver; Lysine; Male; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Proto-Oncogene Proteins c-akt; Risk Factors; RNA, Messenger; Triglycerides | 2018 |
Differences in non-enzymatic glycation products in human dentine and clavicle: changes with aging.
Topics: Adolescent; Adult; Age Determination by Skeleton; Age Determination by Teeth; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Clavicle; Dentin; Female; Forensic Sciences; Humans; Lysine; Male; Middle Aged; Young Adult | 2018 |
Objective Colorimetric Evaluation of Aging-related Articular Cartilage Degeneration.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Arginine; Cartilage, Articular; Chromatography, High Pressure Liquid; Color; Colorimetry; Female; Glycation End Products, Advanced; Humans; Hydroxyproline; Lysine; Male; Middle Aged; Osteoarthritis; Prospective Studies | 2018 |
MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging.
Topics: 3' Untranslated Regions; Aging; Animals; Base Sequence; Brain; Drosophila melanogaster; Drosophila Proteins; Gene Expression Profiling; Histones; Lysine; Methylation; MicroRNAs; Models, Biological; Molecular Chaperones; Mutation; Nerve Degeneration; Peptides; Polycomb Repressive Complex 2; Protein Aggregates; Transcriptome | 2018 |
JNK modifies neuronal metabolism to promote proteostasis and longevity.
Topics: Aging; Animals; Brain; Drosophila; Drosophila Proteins; Gene Ontology; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; JNK Mitogen-Activated Protein Kinases; Longevity; Lysine; Mass Spectrometry; Mutation; Neurons; Pentose Phosphate Pathway; Phosphoprotein Phosphatases; Proteome; Proteostasis; RNA-Seq; Signal Transduction | 2019 |
Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; D-Aspartic Acid; Epiglottis; Female; Forensic Medicine; Humans; Infant; Intervertebral Disc; Lysine; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Young Adult | 2020 |
The association of urinary pentosidine levels with the prevalence of osteoporotic fractures in postmenopausal women.
Topics: Aged; Aging; Arginine; Cohort Studies; Cross-Sectional Studies; Female; Humans; Logistic Models; Lysine; Middle Aged; Multivariate Analysis; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Prevalence | 2019 |
Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications.
Topics: Acetylation; Aging; Animals; Avoidance Learning; Chromatin; Epigenesis, Genetic; Hippocampus; Histones; Lysine; Male; Memory; Methylation; Physical Conditioning, Animal; Promoter Regions, Genetic; Rats, Wistar; Survival Rate | 2019 |
Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Collagen; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Specimen Handling; Tibia; Tissue Culture Techniques; Young Adult | 2013 |
The accumulation of the glycoxidation product N(ε)-carboxymethyllysine in cardiac tissues with age, diabetes mellitus and coronary heart disease.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Coronary Artery Disease; Diabetes Mellitus; Female; Glycosylation; Humans; Infant; Lysine; Male; Middle Aged; Myocardium; Oxidation-Reduction; Smoking; Young Adult | 2013 |
Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.
Topics: Aging; Animals; Cells, Cultured; Cytoplasmic Dyneins; Embryo, Mammalian; Female; Glucagon; Glutamic Acid; Humans; Insulin; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Muscular Atrophy, Spinal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Transfection | 2013 |
Rhein lysinate decreases the generation of β-amyloid in the brain tissues of Alzheimer's disease model mice by inhibiting inflammatory response and oxidative stress.
Topics: Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Anthraquinones; Brain; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Interleukin-6; Lysine; Male; Malondialdehyde; Mice; Oxidative Stress; Sirtuin 1; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Biomarkers; Cardiac Rehabilitation; Cardiovascular Diseases; Disabled Persons; Female; Follow-Up Studies; Frail Elderly; Health Status; Humans; Incidence; Lysine; Male; Prevalence; Prognosis; Retrospective Studies; United States | 2014 |
Age-related changes to layer 3 pyramidal cells in the rhesus monkey visual cortex.
Topics: Aging; Animals; Cognition; Computer Simulation; Dendritic Spines; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Lysine; Macaca mulatta; Male; Membrane Potentials; Microscopy, Electron; Models, Neurological; Neuropsychological Tests; Patch-Clamp Techniques; Pyramidal Cells; Synapses; Visual Cortex | 2015 |
Broad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns.
Topics: Aging; Animals; Animals, Newborn; Cell Cycle; Cell Differentiation; Chromatin Immunoprecipitation; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Ontology; Histones; Kidney; Lung; Lysine; Male; Methylation; Mice, Inbred C57BL; Neurons; Protein Processing, Post-Translational; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2014 |
Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma.
Topics: Adult; Aged; Aging; Arginine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Smoking; Sputum; Vital Capacity; Young Adult | 2014 |
Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cytosol; Humans; Hydroxymethylglutaryl-CoA Synthase; Lysine; Metabolic Networks and Pathways; Mevalonic Acid; Mitochondria; Models, Biological; Mutation; Phenotype; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Maps; Protein Transport; Sumoylation; Ubiquitin | 2014 |
Acetylation of Gly1 and Lys2 promotes aggregation of human γD-crystallin.
Topics: Acetylation; Aged; Aging; Amino Acid Sequence; Cataract; gamma-Crystallins; Glycine; Humans; Lysine; Models, Molecular; Protein Aggregates; Protein Unfolding | 2014 |
Plasma levels of lysine, tyrosine, and valine during pregnancy are independent risk factors of insulin resistance and gestational diabetes.
Topics: Adult; Aging; Asian People; Blood Glucose; Blood Pressure; Diabetes, Gestational; Diet; Energy Intake; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Lysine; Pregnancy; Risk Factors; Tyrosine; Valine | 2015 |
Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice.
Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Caspase 3; Dose-Response Relationship, Drug; Down-Regulation; Galactose; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Peroxidase; Glycation End Products, Advanced; Interleukin-6; Lysine; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pentacyclic Triterpenes; Protein Carbonylation; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Histone methylation patterns in astrocytes are influenced by age following ischemia.
Topics: Acetylation; Acetyltransferases; Aging; Animals; Astrocytes; Brain Ischemia; Cerebral Cortex; Female; Histones; Lysine; Methylation; Methyltransferases; Rats, Sprague-Dawley | 2015 |
Barrel cortex membrane potential dynamics in social touch.
Topics: Afferent Pathways; Aging; Anesthetics; Animals; Animals, Newborn; Female; Interpersonal Relations; Lysine; Male; Membrane Potentials; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Rats; Rats, Wistar; Somatosensory Cortex; Statistics, Nonparametric; Touch; Vibrissae; Wakefulness | 2015 |
Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.
Topics: Aging; Animals; Arteries; Dietary Proteins; Endothelium, Vascular; Lysine; Male; Mice; Mice, Inbred C57BL; Pulse Wave Analysis; Receptor for Advanced Glycation End Products; Sirtuin 1; Vascular Cell Adhesion Molecule-1; Vascular Stiffness | 2015 |
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.
Topics: Aging; Animals; Caenorhabditis elegans; Drosophila melanogaster; Gene Expression Regulation; Histones; Longevity; Lysine; Methylation | 2015 |
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults.
Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness | 2015 |
Estimation of lysine requirements of growing Japanese quail during the fourth and fifth weeks of age.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Coturnix; Diet; Dose-Response Relationship, Drug; Lysine; Nutritional Requirements | 2015 |
Treadmill Exercise Attenuates Retinal Oxidative Stress in Naturally-Aged Mice: An Immunohistochemical Study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Deoxyguanosine; Lysine; Male; Mice; Oxidative Stress; Physical Conditioning, Animal; Retina; Tyrosine | 2015 |
Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature.
Topics: Aging; Animals; Apolipoproteins E; Brain; Coronary Vessels; Endothelium, Vascular; Lysine; Mice, Inbred Strains; Microvessels; Superoxide Dismutase; Survival Rate | 2016 |
Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination.
Topics: Aging; Amino Acid Sequence; Animals; Autoimmunity; Cell Differentiation; Encephalomyelitis, Autoimmune, Experimental; Endopeptidases; Epitopes; HEK293 Cells; Homeostasis; Humans; Inflammation; Lymphocyte Activation; Lymphopenia; Lysine; Mice, Inbred C57BL; Molecular Sequence Data; Peptides; Protein Binding; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Ubiquitination; ZAP-70 Protein-Tyrosine Kinase | 2016 |
Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.
Topics: Aging; Animals; DNA Damage; Drosophila melanogaster; Drosophila Proteins; Fat Body; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Lamins; Lysine; Methylation; Models, Biological; Retroelements | 2016 |
N-carboxymethyllysine as a biomarker for coronary artery disease and age-related macular degeneration.
Topics: Aged; Aging; Biomarkers; Body Mass Index; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lipoproteins; Lysine; Macular Degeneration; Male; Middle Aged; Oxidative Stress; Prevalence; Risk Factors | 2016 |
sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation.
Topics: Aging; Animals; Cell Differentiation; Cell Proliferation; Enzyme Activation; Epidermis; ErbB Receptors; Gene Expression Profiling; Group II Phospholipases A2; Hair Follicle; Histones; Homeostasis; Hyperplasia; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Lysine; Methylation; Mice, Transgenic; Parakeratosis; Proto-Oncogene Proteins c-jun; Sebaceous Glands; Signal Transduction; Stem Cells | 2016 |
FACTORS ASSOCIATED WITH PENTOSIDINE ACCUMULATION IN THE HUMAN VITREOUS.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Humans; Lysine; Male; Middle Aged; Pseudophakia; Regression Analysis; Sex Factors; Vitreous Body; Vitreous Detachment; Young Adult | 2017 |
Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes.
Topics: Aging; Animals; Chromosomes, Mammalian; Histones; Lysine; Metaphase; Methylation; Mice; Oocytes; Ovulation; RNA-Binding Proteins; RNA, Messenger; Spindle Apparatus | 2016 |
Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons.
Topics: Acetylation; Aging; Animals; Brain-Derived Neurotrophic Factor; Cholesterol; Chromatin; Cognition; Epigenesis, Genetic; Hippocampus; Histones; Long-Term Potentiation; Lysine; Methylation; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcription, Genetic; Voriconazole | 2016 |
A-to-I RNA editing of the IGFBP7 transcript increases during aging in porcine brain tissues.
Topics: Aging; Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Brain Mapping; Cerebellum; Chromosome Mapping; Female; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Lung; Lysine; Methylation; Mice; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sulfates; Swine | 2016 |
Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis.
Topics: Aged; Aging; Alveolar Epithelial Cells; Antigens, Neoplasm; Arginine; Epithelial Cells; Extracellular Matrix Proteins; Female; Fibroblasts; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Lung; Lysine; Male; Middle Aged; Mitogen-Activated Protein Kinases; Signal Transduction | 2016 |
The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing.
Topics: Acylation; Aging; Animals; Caenorhabditis elegans; Drosophila melanogaster; Lysine; Mitochondria; Mitochondrial Proteins; Proteomics; Rats; Sirtuin 3 | 2016 |
Oxidative alternations in rat heart homogenate and mitochondria during ageing.
Topics: Aging; Anilino Naphthalenesulfonates; Animals; Electron Transport Complex IV; Fluorescent Dyes; Lipid Peroxidation; Lysine; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tryptophan; Tyrosine | 2008 |
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left | 2008 |
Age-related difference of site-specific histone modifications in rat liver.
Topics: Acetylation; Age Factors; Aging; Amino Acid Sequence; Animals; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Histones; Liver; Lysine; Male; Methylation; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Serine | 2009 |
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Association between serum carboxymethyl-lysine, a dominant advanced glycation end product, and anemia in adults: the Baltimore longitudinal study of aging.
Topics: Adult; Aging; Anemia; Baltimore; Female; Humans; Longitudinal Studies; Lysine; Male | 2008 |
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aorta; Exercise Test; Female; Follow-Up Studies; Glycation End Products, Advanced; Heart Rate; Humans; Lysine; Male; Middle Aged; Prognosis; Prospective Studies; Reference Values; Risk Factors; Vascular Resistance | 2009 |
Elevated serum advanced glycation end products and poor grip strength in older community-dwelling women.
Topics: Aged; Aged, 80 and over; Aging; Disability Evaluation; Female; Glycation End Products, Advanced; Humans; Lysine; Muscle Strength; Muscle Weakness; Prognosis; Women's Health | 2009 |
Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Shape; Dendrites; Epigenesis, Genetic; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Interneurons; Lysine; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Staining and Labeling; Synaptic Transmission | 2009 |
Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development.
Topics: Acetylation; Aging; Animals; Cell Nucleus; Embryonic Development; Female; Fertilization; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Lysine; Male; Meiosis; Mice; Mice, Inbred Strains; Oocytes; Spindle Apparatus; Superovulation; Zygote | 2010 |
Urinary levels of pentosidine and the risk of fracture in postmenopausal women: the OFELY study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone Density; Epidemiologic Methods; Female; Hip Joint; Humans; Lumbar Vertebrae; Lysine; Middle Aged; Osteoporotic Fractures; Postmenopause; Spinal Fractures | 2010 |
Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women.
Topics: Aged; Aging; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Predictive Value of Tests; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Residence Characteristics; Risk Factors | 2009 |
Pentosidine accumulates in the aging vitreous body: a gender effect.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Ciliary Body; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Menopause; Middle Aged; Sex Characteristics; Vitreous Body; Young Adult | 2009 |
Association between dietary protein and change in body composition among children (EYHS).
Topics: Adolescent; Aging; Algorithms; Arginine; Body Composition; Body Mass Index; Child; Dietary Proteins; Female; Health Surveys; Humans; Lysine; Male; Motor Activity; Obesity; Puberty; Sex Characteristics; Social Class | 2009 |
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men.
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase | 2009 |
Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Community Health Planning; Female; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Muscle Strength; Odds Ratio; Walking | 2010 |
Serum carboxymethyl-lysine, a dominant advanced glycation end product, is associated with chronic kidney disease: the Baltimore longitudinal study of aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Baltimore; Chronic Disease; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney Diseases; Linear Models; Longitudinal Studies; Lysine; Male; Middle Aged; Racial Groups; Smoking | 2010 |
Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.
Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Cattle; Child; Crystallins; Diabetes Mellitus; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; Lens, Crystalline; Leucine; Lysine; Metals; Mice; Mice, Inbred C57BL; Middle Aged; Molecular Structure; Oxidants; Oxidation-Reduction; Rabbits; Regression Analysis; Young Adult | 2009 |
Neuroscience. Epigenetics and cognitive aging.
Topics: Acetylation; Aging; Animals; Chromatin; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Formins; Gene Expression Regulation; Hippocampus; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Memory; Memory Disorders; Mice; Microfilament Proteins; Nerve Tissue Proteins; Nuclear Proteins; Transcription, Genetic | 2010 |
Altered histone acetylation is associated with age-dependent memory impairment in mice.
Topics: Acetylation; Aging; Animals; Chromatin; Chromatin Assembly and Disassembly; Conditioning, Psychological; Epigenesis, Genetic; Fear; Formins; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Learning; Lysine; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Microfilament Proteins; Nerve Tissue Proteins; Nuclear Proteins; Signal Transduction; Transcription Initiation Site; Transcription, Genetic; Up-Regulation | 2010 |
Local axon collaterals of lamina I projection neurons in the spinal cord of young rats.
Topics: Aging; Animals; Axons; Image Processing, Computer-Assisted; Lumbar Vertebrae; Lysine; Neural Pathways; Neurons; Photomicrography; Rats; Rats, Wistar; Spinal Cord | 2010 |
Accurate quantification of more than 4000 mouse tissue proteins reveals minimal proteome changes during aging.
Topics: Aging; Animals; Chromatography, Liquid; Disulfides; Frontal Lobe; Hippocampus; Lysine; Mass Spectrometry; Mice; Mice, Inbred C57BL; Proteins; Proteome; Proteomics; Time Factors; Tissue Distribution | 2011 |
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy.
Topics: Acetylation; Age Factors; Aging; Amino Acid Sequence; Animals; Cardiomegaly; Cyclophilins; Cyclosporine; Disease Models, Animal; Humans; Lysine; Mice; Mice, 129 Strain; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myocytes, Cardiac; Peptidyl-Prolyl Isomerase F; Protein Conformation; Sirtuin 3; Structure-Activity Relationship; Time Factors | 2010 |
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Asthma; Cross-Linking Reagents; Female; Humans; Lysine; Male; Middle Aged; Respiratory Function Tests; Sputum; Young Adult | 2011 |
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.
Topics: Aging; Arginine; Embryo Implantation; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Glycation End Products, Advanced; Humans; Infertility; Lysine; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies | 2011 |
Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
Topics: Aging; Animals; Base Sequence; Cartilage, Articular; Chondrocytes; Chromatin Immunoprecipitation; Epigenesis, Genetic; Gene Knockdown Techniques; Histone Demethylases; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Molecular Sequence Data; NFATC Transcription Factors; Osteoarthritis; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Up-Regulation | 2011 |
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice.
Topics: Acetylation; Aging; Aging, Premature; Animals; Cells, Cultured; Cellular Senescence; Chromosomal Proteins, Non-Histone; Disease Models, Animal; DNA Repair; DNA-Binding Proteins; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Lamin Type A; Lysine; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Knockout; Nuclear Matrix; Nuclear Proteins; Protein Precursors; RNA, Small Interfering; Tumor Suppressor p53-Binding Protein 1 | 2011 |
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage.
Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Case-Control Studies; Cattle; Collagen; Contrast Media; Hindlimb; Ioxaglic Acid; Lysine; Patella; Tetroses; Tomography, X-Ray Computed | 2011 |
Advanced glycation end product level, diabetes, and accelerated cognitive aging.
Topics: Aged; Aging; Arginine; Chi-Square Distribution; Cognition Disorders; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Longitudinal Studies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests; Odds Ratio | 2011 |
Features, causes and consequences of splanchnic sequestration of amino acid in old rats.
Topics: Age Factors; Aging; Amino Acids; Animals; Arginine; Intestinal Mucosa; Kupffer Cells; Liver; Lysine; Protein Biosynthesis; Rats; Viscera | 2011 |
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli).
Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Female; Glycation End Products, Advanced; Longevity; Lysine; Male; Mole Rats; Skin | 2012 |
In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage.
Topics: Aged; Aging; Arginine; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Collagen; Female; Glycation End Products, Advanced; Humans; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis, Knee; Severity of Illness Index | 2012 |
Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation.
Topics: Acetylcysteine; Aging; Animals; Hippocampus; Lysine; Male; Neuronal Plasticity; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 2012 |
Circulating selenium and carboxymethyl-lysine, an advanced glycation endproduct, are independent predictors of anemia in older community-dwelling adults.
Topics: Aged; Aged, 80 and over; Aging; Anemia; Biomarkers; Cohort Studies; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Incidence; Italy; Longitudinal Studies; Lysine; Male; Oxidative Stress; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Selenium | 2012 |
Ageing in Werner syndrome.
Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome | 2012 |
Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells.
Topics: Aging; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Colitis; Colon; Death-Associated Protein Kinases; Dextran Sulfate; Epithelial Cells; Gene Expression; Histones; Intestinal Mucosa; Lysine; Male; Methylation; Mice; Mice, Inbred BALB C; Neoplasms | 2012 |
Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice.
Topics: Aging; Animals; Enzyme Inhibitors; Insulin; Insulin Resistance; Lysine; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide Synthase Type II; Nitrosation; Physical Conditioning, Animal; Signal Transduction | 2013 |
Reduction of type IV collagen by upregulated miR-29 in normal elderly mouse and klotho-deficient, senescence-model mouse.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Collagen Type IV; Creatinine; Deoxyguanosine; Gene Expression Profiling; Gene Knockdown Techniques; Gene Silencing; Genes, Reporter; Glucuronidase; HEK293 Cells; Humans; Klotho Proteins; Lysine; Male; Mice; Mice, Inbred ICR; MicroRNAs; Models, Biological; Up-Regulation | 2012 |
Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.
Topics: Adult; Aged; Aging; Blood Chemical Analysis; Collagen; Coronary Artery Disease; Diastole; Echocardiography; Glycation End Products, Advanced; Hemodynamics; Humans; Lysine; Male; Middle Aged; Myocardium; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Ventricular Dysfunction, Left | 2012 |
Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study.
Topics: Age Factors; Aging; Animals; Biomarkers; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Hippocampus; Histones; Lysine; Male; Physical Exertion; Rats; Rats, Wistar | 2013 |
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease.
Topics: Adolescent; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Neuroglia; Neurons; Oxidative Stress | 2002 |
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging.
Topics: Aging; Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liquid; Histones; Humans; Lysine; Mass Spectrometry; Metalloendopeptidases; Methylation; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Serine Endopeptidases; Time Factors | 2002 |
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyramidal Cells | 2002 |
Unexpected carbonyl mobility in aminoketoses: the key to major Maillard crosslinks.
Topics: Aging; Amino Sugars; Arginine; Carbon Radioisotopes; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Radioactive Tracers | 2002 |
Lysine need of heavy broiler males applying the ideal protein concept.
Topics: Adipose Tissue; Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Glycine max; Lysine; Male; Muscle, Skeletal; Nutritional Requirements; Weight Gain; Zea mays | 2002 |
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics.
Topics: Aging; Animals; Catalysis; Cattle; Cross-Linking Reagents; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Guanidines; Indicators and Reagents; Lysine; Maillard Reaction; Methylene Blue; Renin; Ribonuclease, Pancreatic; Somatostatin | 2003 |
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney.
Topics: Aging; Animals; Antibodies; Antibody Specificity; Basement Membrane; Biomarkers; Collagen; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Oxidative Stress; Proteins; Rats; Rats, Wistar | 2003 |
Aging alters dendritic morphology, input resistance, and inhibitory signaling in dentate granule cells of the rhesus monkey.
Topics: Action Potentials; Aging; Animals; Behavior, Animal; Cognition; Dendrites; Dentate Gyrus; Female; Lysine; Macaca mulatta; Male; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Receptors, GABA-A; Synaptic Transmission | 2003 |
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.
Topics: Adenosine Triphosphate; Aging; Animals; Blotting, Western; Cell Survival; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Lysine; Male; Methylation; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Oxygen; Oxygen Consumption; Peptides; Rats; Rats, Wistar; Stress, Physiological; Time Factors | 2003 |
Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Glomerular Filtration Rate; Humans; Inflammation; Kidney Failure, Chronic; Lysine; Male; Mortality; Nutrition Disorders; Prognosis; Prospective Studies; Renal Dialysis; Survival Analysis | 2003 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Crosses, Genetic; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Islets of Langerhans; Lysine; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvaldehyde | 2003 |
The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates.
Topics: Aging; Analysis of Variance; Animals; Arginine; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Collagen; Food Deprivation; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Regression Analysis; Saimiri; Skin | 2003 |
Nutritional and biochemical effects of 19-nortestosterone with lysine supplements in aging convalescents.
Topics: Aging; Dietary Supplements; Lysine; Nandrolone; Testosterone | 1958 |
The effect of age on the net requirements for nitrogen, lysine and tryptophan by the well-fed rat.
Topics: Aging; Animals; Biochemical Phenomena; Lysine; Nitrogen; Purines; Rats; Tryptophan | 1959 |
AGING IN CONNECTIVE TISSUE: A DYNAMIC PROCESS.
Topics: Aging; Cholesterol; Collagen; Connective Tissue; Hexosamines; Histology; Lipid Metabolism; Lysine; Physiology; Proteins; Rats; Research | 1963 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
UPTAKE OF C-14-L-LYSINE INTO SEGMENTS OF NORMAL RAT SCIATIC NERVE.
Topics: Aging; Carbon Isotopes; Lysine; Metabolism; Rats; Research; Sciatic Nerve | 1965 |
COMPARISON OF TESTICULAR PROTEIN LABELLING IN CRYPTORCHIDISM INDUCED IN PREPUBERTAL AND ADULT RATS.
Topics: Adult; Aging; Carbon Isotopes; Cryptorchidism; Histocytochemistry; Humans; Lysine; Male; Proteins; Rats; Research; Testis; Transplantation, Autologous | 1965 |
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen | 2003 |
Lysine needs of summer-reared male broilers from six to eight weeks of age.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Dietary Proteins; Glycine max; Hot Temperature; Lysine; Male; Mortality; Nutritional Requirements; Seasons; Weight Gain; Zea mays | 2003 |
Maturation of layer V pyramidal neurons in the rat prefrontal cortex: intrinsic properties and synaptic function.
Topics: Action Potentials; Aging; Animals; Dendrites; Electrophysiology; Female; Histocytochemistry; In Vitro Techniques; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses | 2004 |
Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.
Topics: Aging; Animals; Animals, Newborn; Arginine; Cell Death; Cryptorchidism; Cytoprotection; Gene Expression; Humans; Lysine; Male; Mice; Mice, Transgenic; Mutation; Spermatogenesis; Spermatozoa; Testis; Transgenes; Ubiquitin | 2003 |
2-ammonio-6-(3-oxidopyridinium-1-yl)hexanoate (OP-lysine) is a newly identified advanced glycation end product in cataractous and aged human lenses.
Topics: Aged; Aging; Ascorbic Acid; Caproates; Cataract; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glycation End Products, Advanced; Humans; Hydrolysis; Lens, Crystalline; Light; Lysine; Magnetic Resonance Spectroscopy; Middle Aged; Models, Chemical; Pyridinium Compounds; Time Factors; Ultraviolet Rays; Water | 2004 |
Growth responses to dietary lysine at high and low ambient temperature in male turkeys.
Topics: Aging; Animal Feed; Animals; Diet; Eating; Lysine; Male; Meat; Muscle, Skeletal; Nutritional Requirements; Temperature; Turkeys; Weight Gain | 2003 |
Age-related changes of noncalcified collagen in human cortical bone.
Topics: Adult; Aged; Aging; Arginine; Bone Remodeling; Cadaver; Collagen; Cross-Linking Reagents; Elasticity; Female; Femoral Fractures; Femur; Haversian System; Humans; Lysine; Male; Middle Aged; Osteogenesis; Osteoporosis; Protein Denaturation | 2003 |
Association between pentosidine and arteriosclerosis in patients receiving hemodialysis.
Topics: Aged; Aging; Aorta, Abdominal; Aortic Diseases; Arginine; Arteriosclerosis; Calcinosis; Female; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors; Tomography, X-Ray Computed | 2004 |
N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cytoplasm; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; tau Proteins | 2004 |
Effects of copper source on phosphorus retention in broiler chicks and laying hens.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Calcification, Physiologic; Chickens; Citrates; Copper; Copper Sulfate; Diet; Dietary Supplements; Lysine; Oviposition; Phosphorus, Dietary; Weight Gain | 2004 |
Glycation-induced inactivation of NADP(+)-dependent isocitrate dehydrogenase: implications for diabetes and aging.
Topics: Aging; Animals; Antioxidants; Cell Line; Cysteine; Diabetes Mellitus; Fructose; Glucose; Glycosylation; Humans; Isocitrate Dehydrogenase; Lysine; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats | 2004 |
Changes in dolichol and pentosidine levels in the age-mismatched heterotopically transplanted rat heart.
Topics: Aging; Animals; Arginine; Biological Clocks; Connective Tissue; Dolichols; Heart Transplantation; Lysine; Male; Myocardium; Papillary Muscles; Rats; Rats, Inbred Lew; Transplantation, Heterotopic | 2004 |
Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys.
Topics: Action Potentials; Aging; Animals; Behavior, Animal; Cognition; Electrophysiology; Learning; Lysine; Macaca mulatta; Membrane Potentials; Memory; Memory, Short-Term; Patch-Clamp Techniques; Prefrontal Cortex; Psychomotor Performance; Pyramidal Cells; Recognition, Psychology | 2005 |
Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice.
Topics: Age Factors; Aging; Aldehydes; Animals; Body Weight; Dinoprost; Extracellular Matrix; Galectin 3; Glomerulonephritis; Glycation End Products, Advanced; Kidney Glomerulus; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Enzymic and non-enzymic cross-linking mechanisms in relation to turnover of collagen: relevance to aging and exercise.
Topics: Aging; Bone and Bones; Collagen; Connective Tissue; Exercise; Glucose; Glycation End Products, Advanced; Humans; Hydroxylation; Lysine; Maillard Reaction; Oxidation-Reduction; Physical Exertion; United Kingdom | 2005 |
Immunohistochemical localization of advanced glycation end products in pinguecula.
Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles | 2006 |
epsilon-Glycation, APP and Abeta in ageing and Alzheimer disease: a hypothesis.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Glycation End Products, Advanced; Humans; Lysine; Models, Neurological | 2006 |
Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs.
Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Chondroitin Sulfate Proteoglycans; Collagen; Discitis; Extracellular Matrix Proteins; Humans; Intervertebral Disc; Lectins, C-Type; Lysine; Middle Aged; Proteoglycans | 2006 |
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats.
Topics: Age Factors; Aging; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Cyclic N-Oxides; Dietary Supplements; Homeostasis; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Lysine; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Inbred F344; Spin Labels; Triglycerides | 2006 |
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of aged rat.
Topics: Age Factors; Aging; Animals; Antibodies; Capillaries; Choroid; Choroidal Neovascularization; Glycation End Products, Advanced; Lysine; Macular Degeneration; Male; Organ Culture Techniques; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2007 |
Robust correlations between action potential duration and the properties of synaptic connections in layer 4 interneurones in neocortical slices from juvenile rats and adult rat and cat.
Topics: Action Potentials; Aging; Animals; Cats; Data Interpretation, Statistical; Electrophysiology; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Lysine; Male; Neocortex; Neural Pathways; Rats; Rats, Sprague-Dawley; Synapses; Visual Cortex | 2007 |
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Diet; Dinoprost; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lysine; Male; Middle Aged; Oxidative Stress; Pyruvaldehyde | 2007 |
Advanced glycation endproducts: a biomarker for age as an outcome predictor after cardiac surgery?
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Coronary Artery Bypass; Glycation End Products, Advanced; Heart; Humans; Lysine; Middle Aged; Pericardial Effusion; Predictive Value of Tests; Treatment Outcome | 2007 |
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle.
Topics: Actins; Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Muscle Contraction; Muscle Strength; Muscular Diseases; Myofibrils; Myosins; Quadriceps Muscle | 2007 |
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2007 |
Contents of pentosidine in the tissue of the intervertebral disc as an indicator of the human age.
Topics: Adolescent; Adult; Age Determination by Skeleton; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Humans; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged | 2007 |
Age-dependent effect of oxidative stress on cardiac sarcoplasmic reticulum vesicles.
Topics: Age Factors; Aging; Animals; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Lipid Peroxidation; Lysine; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sarcoplasmic Reticulum; Subcellular Fractions; Thiobarbituric Acid Reactive Substances; Tryptophan | 2008 |
Aging, diabetes, and renal failure catalyze the oxidation of lysyl residues to 2-aminoadipic acid in human skin collagen: evidence for metal-catalyzed oxidation mediated by alpha-dicarbonyls.
Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aging; Child; Child, Preschool; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Humans; Infant; Infant, Newborn; Lysine; Middle Aged; Oxidation-Reduction; Skin; Skin Aging | 2008 |
Developmental changes in amino acid transport in the chicken erythrocyte.
Topics: Aging; Amino Acids; Animals; Chickens; Erythrocytes; Glycine; Kinetics; Leucine; Lysine | 1983 |
Ageing of the spinal ganglion neurons in the rat: a radioautographic study following injection of [3H]lysine.
Topics: Aging; Animals; Autoradiography; Axonal Transport; Ganglia, Spinal; Lysine; Male; Neurons; Rats; Rats, Inbred Strains; Tritium | 1980 |
Differences in the extent and heterogeneity of lysyl hydroxylation in embryonic chick cranial and long bone collagens.
Topics: Aging; Animals; Bone and Bones; Bone Development; Chick Embryo; Chickens; Collagen; Hydroxylysine; Lathyrism; Lysine; Skull | 1983 |
[Supplementation of the amino acid composition of protein-rich wheat with protein concentrates and L-lysine in rations for laying hens. 4. Effect of various rearing diets on crude protein, fat and ash contents of the utilizable and nonutilizable parts of
Topics: Aging; Animals; Body Composition; Body Weight; Chickens; Diet; Dietary Fats; Dietary Proteins; Female; Lysine; Minerals; Oviposition | 1983 |
The amino acid requirements of growing turkeys. 2. Experimental validation of model-calculated requirements for sulfur amino acids and lysine.
Topics: Aging; Amino Acids, Sulfur; Animals; Body Weight; Diet; Lysine; Male; Models, Biological; Nutritional Requirements; Turkeys | 1983 |
Age-related changes in non-enzymatic glycosylation of human basement membranes.
Topics: Adolescent; Adult; Aged; Aging; Basement Membrane; Diabetes Mellitus; Female; Humans; Kidney Glomerulus; Lens Capsule, Crystalline; Lysine; Male; Membrane Proteins; Middle Aged | 1983 |
Nonenzymatic glycation of human lens crystallin. Effect of aging and diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aging; Crystallins; Diabetes Mellitus; Female; Glucose; Humans; Infant; Lens, Crystalline; Lysine; Male; Middle Aged; Solubility | 1984 |
Tissue distribution of carnitine biosynthetic enzymes in man.
Topics: Adolescent; Adult; Aging; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Aldehyde-Lyases; Carnitine; Child; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Glucuronates; Humans; Infant; Kinetics; Lactones; Lysine; Male; Middle Aged; Mixed Function Oxygenases; Organ Specificity; Tissue Distribution | 1980 |
Effect of age on ease of B-cell tolerance induction.
Topics: Aging; Animals; Antibody Affinity; B-Lymphocytes; Dinitrobenzenes; Glutamates; Immune Tolerance; Lysine; Male; Mice; Mice, Inbred BALB C | 1980 |
Protein requirements of adult cebus monkeys (Cebus albifrons).
Topics: Aging; Amino Acids; Animals; Body Weight; Cebidae; Cebus; Cholesterol; Dietary Proteins; Female; Food Analysis; Lactalbumin; Lysine; Male; Nutritional Requirements | 1980 |
Rat brain protein synthesis declines during postdevelopmental aging.
Topics: Aging; Animals; Brain; Female; Lysine; Nerve Tissue Proteins; Rats | 1980 |
Nonenzymatic browning in vivo: possible process for aging of long-lived proteins.
Topics: Aging; Animals; Cattle; Chemical Phenomena; Chemistry; Crystallins; Diabetes Mellitus; Glucose; Glucosephosphates; In Vitro Techniques; Lysine; Proteins; Spectrophotometry, Ultraviolet | 1981 |
Digestion in the pigs between 7 and 35 d of age. 4. The digestion of amino acids in pigs given milk and soya-bean proteins.
Topics: Aging; Amino Acids; Animals; Dietary Proteins; Digestion; Glycine max; Ileum; Intestine, Small; Lysine; Methionine; Milk Proteins; Plant Proteins; Swine | 1981 |
Influence of prenatal hypoxia on brain development: effects on body weight, brain weight, DNA, protein, acetylcholinesterase, 3-quinuclidinyl benzilate binding, and in vivo incorporation of [14C]lysine into subcellular fractions.
Topics: Acetylcholinesterase; Aging; Animals; Body Weight; Brain; DNA; Female; Fetal Diseases; Fetus; Hypoxia; Lysine; Nerve Tissue Proteins; Organ Size; Pregnancy; Quinuclidines; Quinuclidinyl Benzilate; Rats; Subcellular Fractions | 1981 |
Postnatal development of trypsin-like esteroproteases in mouse submandibular gland.
Topics: Aging; Animals; Animals, Newborn; Female; Histocytochemistry; Isoenzymes; Lysine; Male; Mice; Mice, Inbred Strains; Sex Factors; Submandibular Gland; Trypsin | 1981 |
[Effect of a frequent administration of a daily lysine supplement on the utilization of nutrients in pigs from 20 to 100 kg body weight. 1. Description of methods, growth and food utilization].
Topics: Aging; Animals; Body Weight; Lysine; Nutritional Physiological Phenomena; Swine | 1981 |
[Lysine requirement of fattening boars with reference to their performance. 4. Selected quantitative characteristics of the carcass and derivation of the lysine requirement].
Topics: Adipose Tissue; Aging; Animals; Digestion; Energy Metabolism; Lysine; Male; Nutritional Requirements; Swine | 1981 |
Lysine and protein requirements of growing turkeys.
Topics: Aging; Animals; Body Weight; Dietary Proteins; Female; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Turkeys | 1981 |
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine | 1982 |
Developmental pattern of cystine transport in isolated rat renal tubules.
Topics: Aging; Animals; Biological Transport; Cystine; Female; Kidney Cortex; Kidney Tubules; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains | 1982 |
Induction of immunological tolerance to single-stranded and double-stranded DNA.
Topics: Aging; Animals; Antibody-Producing Cells; Antigens; Autoantibodies; DNA; DNA, Single-Stranded; Female; Glutamates; Hemolytic Plaque Technique; Immune Tolerance; Lysine; Mice; Mice, Inbred C3H; Mice, Inbred NZB | 1982 |
Changes in the characteristics of collagen of young male garden lizards following centrophenoxine and lysine treatment.
Topics: Aging; Animals; Bone and Bones; Collagen; Glycolates; Lizards; Lysine; Male; Meclofenoxate; Skin; Tendons | 1982 |
Effect of continuous infusion of lysine via different routes and hepatic vagotomy on dietary choice in rats.
Topics: Aging; Animals; Diet; Eating; Food Preferences; Infusions, Parenteral; Injections, Intraventricular; Liver; Lysine; Male; Rats; Rats, Sprague-Dawley; Vagotomy | 1995 |
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
Topics: Aged; Aged, 80 and over; Aging; Carbamates; Crystallins; Female; Glutathione; Guanidine; Guanidines; Humans; Lysine; Male; Middle Aged; Renal Insufficiency; Solubility; Spectrometry, Mass, Fast Atom Bombardment; Water | 1995 |
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
Topics: Aging; Animals; Arginine; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Energy Intake; Female; Food Deprivation; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rats; Rats, Inbred BN; Skin | 1995 |
Effect on performance and carcass characteristics of nursery to finisher pigs fed reduced crude protein, amino acid-supplemented diets.
Topics: Aging; Amino Acids; Animals; Body Composition; Body Weight; Diet; Dietary Proteins; Female; Food, Fortified; Kidney; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Swine; Threonine; Trypsin | 1995 |
Ideal digestible lysine level for early- and late-finishing swine.
Topics: Aging; Amino Acids; Animal Feed; Animals; Blood Urea Nitrogen; Body Composition; Female; Food, Fortified; Glycine max; Lysine; Male; Nutritional Requirements; Random Allocation; Sex Characteristics; Swine; Weight Gain; Zea mays | 1995 |
N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins.
Topics: Aging; Antigens; Chromatography, Gel; Crystallins; Enzyme-Linked Immunosorbent Assay; Fructose; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Kinetics; Lysine; Maillard Reaction; Serum Albumin, Bovine | 1995 |
Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Extracellular Matrix; Hydroxyproline; Lung; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Solubility; Spectrometry, Fluorescence | 1995 |
Juvenile visual callosal axons in kittens display origin- and fate-related morphology and distribution of arbors.
Topics: Aging; Animals; Axons; Cats; Cerebral Cortex; Corpus Callosum; Image Processing, Computer-Assisted; Lysine; Neural Pathways | 1994 |
Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Dipeptides; Energy Intake; Granulation Tissue; Lysine; Male; Rats; Rats, Inbred F344; Time Factors; Wound Healing | 1995 |
Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage.
Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Collagen; Female; Lysine; Maillard Reaction; Osteoarthritis; Peptide Mapping; Protein-Lysine 6-Oxidase; Rabbits; Solubility | 1995 |
Influence of age and long-term dietary restriction on enzymatically mediated crosslinks and nonenzymatic glycation of collagen in mice.
Topics: Aging; Animals; Aorta; Arginine; Collagen; Cross-Linking Reagents; Food Deprivation; Glycosylation; Lung; Lysine; Male; Mice; Mice, Inbred C57BL; Skin; Spectrometry, Fluorescence; Tendons | 1994 |
L-arginine reduces kidney collagen accumulation and N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse.
Topics: Aging; Animals; Arginine; Basement Membrane; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Hydroxyproline; Kidney; Kidney Glomerulus; Lysine; Mice | 1994 |
Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Bone Diseases; Cartilage, Articular; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Linking Reagents; Female; Femur Head Necrosis; Hip Joint; Humans; Joint Diseases; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Osteoporosis | 1994 |
Differential effects of type 2 (non-insulin-dependent) diabetes mellitus on pentosidine formation in skin and glomerular basement membrane.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Basement Membrane; Biomarkers; Child; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Infant; Kidney Glomerulus; Lysine; Male; Middle Aged; Skin; Skin Aging | 1993 |
Characterization of macromolecule resonances in the 1H NMR spectrum of rat brain.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain Chemistry; Chromatography, Gel; Cytosol; Female; Hydrogen; Image Enhancement; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Methionine; Myelin Sheath; Proteins; Rats; Rats, Sprague-Dawley | 1993 |
Postnatal development and specification of the cat's visual corticotectal projection: efferents from the posteromedial lateral suprasylvian area.
Topics: Aging; Animals; Animals, Newborn; Axons; Cats; Cerebral Aqueduct; Efferent Pathways; Lysine; Neurons; Superior Colliculi; Synaptic Transmission; Thalamus; Visual Cortex | 1993 |
Quantification of the cross-link pentosidine in serum from normal and uremic subjects.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Uremia | 1993 |
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Diabetes Mellitus, Type 1; Female; Glycosylation; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.
Topics: Aging; Animals; Arginine; Cattle; Collagen; Cross-Linking Reagents; Diet; Dogs; Glucose; Humans; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Rats; Regression Analysis; Saimiri; Skin; Swine | 1996 |
Interaction of diet composition and a reduced nocturnal temperature regimen in weanling pigs.
Topics: Aging; Analysis of Variance; Animal Feed; Animals; Body Temperature Regulation; Circadian Rhythm; Diet; Female; Lysine; Male; Random Allocation; Swine; Temperature; Weaning | 1995 |
The impact of environment and antimicrobial agents on the growth response of early-weaned pigs to spray-dried porcine plasma.
Topics: Aging; Animals; Anti-Bacterial Agents; Blood Proteins; Copper; Eating; Environment; Female; Hydrochloric Acid; Lysine; Male; Milk; Random Allocation; Swine; Weaning | 1995 |
Evaluation of copper sulfate and a copper lysine complex as growth promoters for weanling swine.
Topics: Aging; Animals; Brain Chemistry; Copper; Copper Sulfate; Diet; Eating; Female; Iron; Kidney; Liver; Lymphocyte Activation; Lysine; Male; Random Allocation; Swine; Weaning; Weight Gain; Zinc | 1995 |
Interactive effects of feed intake and stage of growth on the lysine requirement of pigs.
Topics: Aging; Animals; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Eating; Lysine; Male; Nutritional Requirements; Swine | 1995 |
Direct quantification of pentosidine in urine and serum by HPLC with column switching.
Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Time Factors; Uremia | 1996 |
Relative responses of protein turnover in three different skeletal muscles to dietary lysine deficiency in chicks.
Topics: Aging; Analysis of Variance; Animal Feed; Animals; Chickens; Diet; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Tritium | 1996 |
The role of glycation cross-links in diabetic vascular stiffening.
Topics: Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Elastin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Time Factors | 1996 |
Effects of immune challenge, dietary energy density, and source of energy on performance and immunity in weanling pigs.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antibodies; Cell Division; Dietary Fats; Energy Intake; Energy Metabolism; Escherichia coli; Female; Lipopolysaccharides; Lymphocytes; Lysine; Male; Swine; Threonine; Tryptophan; Weight Gain | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence | 1996 |
[Activity of basic arginine- and lysine-residue cleaving carboxypeptidase in rats of various ages].
Topics: Aging; Animals; Arginine; Brain; Carboxypeptidases; Hydrolysis; Lysine; Male; Rats | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E | 1997 |
Influence of dietary lysine levels and arginine:lysine ratios on performance of broilers exposed to heat or cold stress during the period of three to six weeks of age.
Topics: Aging; Animals; Arginine; Body Composition; Body Temperature; Chickens; Cold Temperature; Diet; Dose-Response Relationship, Drug; Eating; Hot Temperature; Lysine; Male; Meat; Poultry Diseases; Regression Analysis; Stress, Physiological; Time Factors; Weight Gain | 1997 |
Dietary interactions between lysine and threonine in broilers.
Topics: Aging; Animals; Antibody Formation; Body Composition; Chickens; Diet; Dose-Response Relationship, Drug; Drug Interactions; Immunity, Cellular; Lysine; Male; Meat; Mortality; Threonine; Time Factors; Weight Gain | 1997 |
Age-related increase in an advanced glycation end product in penile tissue.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Penile Erection; Penis; Sexual Dysfunction, Physiological | 1995 |
Ageing promotes the increase of early glycation Amadori product as assessed by epsilon-N-(2-furoylmethyl)-L-lysine (furosine) levels in rodent skin collagen. The relationship to dietary restriction and glycoxidation.
Topics: Aging; Animals; Chromatography, High Pressure Liquid; Collagen; Diet; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Humans; Kinetics; Lysine; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Rats; Rats, Inbred F344; Skin | 1997 |
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbohydrate Metabolism; Child; Collagen; Crystallins; Humans; Lens, Crystalline; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Ribonucleases; Skin | 1997 |
Diphasic allometric growth of body components in white Leghorn pullets fed ad libitum and restricted diets.
Topics: Aging; Animals; Body Composition; Chickens; Diet; Diet, Protein-Restricted; Dietary Proteins; Dose-Response Relationship, Drug; Eating; Female; Lysine; Models, Biological; Models, Statistical | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons.
Topics: Adolescent; Aged; Aging; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipofuscin; Lysine; Nerve Degeneration; Nerve Tissue Proteins; Neurons | 1997 |
Age-related association of tail tendon break time with tissue pentosidine in DBA/2 vs C57BL/6 mice: the effect of dietary restriction.
Topics: Aging; Animals; Arginine; Collagen; Diet; Female; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Denaturation; Species Specificity; Tail; Tendons; Time Factors | 1997 |
Evaluation of protein and energy quality of rendered spent hen meals.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Energy Intake; Lysine; Male; Methionine; Nutritive Value | 1997 |
Effect of dietary aminoguanidine on tissue pentosidine and reproductive performance in broiler breeder hens.
Topics: Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Chickens; Collagen; Diet; Egg Shell; Female; Fertility; Guanidines; Lysine; Male; Oviposition; Random Allocation; Reproduction; Skin; Specific Gravity | 1997 |
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphyses; Dipeptides; Femur; Histidine; Humans; Indicators and Reagents; Infant; Lysine; Male; Middle Aged; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence | 1997 |
Evaluation of the interrelationships among lactose and protein sources in diets for segregated early-weaned pigs.
Topics: Aging; Animals; Blood Proteins; Diet; Dietary Proteins; Lactose; Lysine; Male; Probability; Random Allocation; Soybean Proteins; Swine; Weaning | 1997 |
1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Child; Child, Preschool; Fetus; Humans; Immunohistochemistry; Infant; Infant, Newborn; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged | 1997 |
Basal synthesis of heat shock protein 70 increases with age in rat kidneys.
Topics: Actins; Aging; Animals; Arginine; HSP70 Heat-Shock Proteins; Kidney; Lysine; Male; Rats; Rats, Wistar; RNA, Messenger; RNA, Ribosomal | 1998 |
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomechanical Phenomena; Cartilage, Articular; Child; Child, Preschool; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Hydroxylysine; Infant; Lysine; Middle Aged; Protein Processing, Post-Translational | 1998 |
Advanced glycosylation end products in adrenal lipofuscin.
Topics: Adrenal Cortex; Adrenal Glands; Aging; Animals; Antibodies; Brain; Cerebellum; Cerebral Cortex; Cytoplasmic Granules; Fluorescent Antibody Technique, Direct; Glycation End Products, Advanced; Immunoenzyme Techniques; Immunohistochemistry; Lipofuscin; Lysine; Male; Neurons; Purkinje Cells; Rats; Rats, Inbred F344; Zona Reticularis | 1998 |
Nonenzymatic glycation of cartilage proteoglycans: an in vivo and in vitro study.
Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Animals; Arginine; Cartilage; Cartilage, Articular; Cattle; Chromatography, Agarose; Cross-Linking Reagents; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Lectins, C-Type; Lysine; Middle Aged; Molecular Weight; Osteoarthritis; Proteoglycans | 1997 |
Postnatal development of excitatory synaptic input to the rat neostriatum: an electron microscopic study.
Topics: Aging; Animals; Axons; Immunohistochemistry; Lysine; Microscopy, Electron; Neostriatum; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Synapses | 1998 |
Role of advanced glycation end products in aging collagen. A scanning force microscope study.
Topics: Aging; Animals; Arginine; Collagen; Glycation End Products, Advanced; Lysine; Male; Microscopy; Osmolar Concentration; Periodicity; Rats; Rats, Wistar; Tail; Tendons | 1998 |
Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.
Topics: Aging; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; In Vitro Techniques; Lysine; Maillard Reaction; Pyruvaldehyde; Ribonucleases | 1998 |
Collagen crosslinks in human lumbar intervertebral disc aging.
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cadaver; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged | 1998 |
Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Brain; Entorhinal Cortex; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Inclusion Bodies; Lipofuscin; Lysine; Maillard Reaction; Middle Aged; Ubiquitins | 1998 |
The effect of dietary crude protein on growth, ammonia concentration, and litter composition in broilers.
Topics: Aging; Amino Acids; Ammonia; Animal Feed; Animals; Chickens; Dietary Proteins; Food, Fortified; Lysine; Male; Waste Products; Weight Gain | 1998 |
Determination of urinary and serum pentosidine and its application to elder patients.
Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Lysine; Middle Aged | 1998 |
Effects of continuous ambulatory peritoneal dialysis and kidney transplantation on advanced glycation endproducts in the skin and peritoneum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Skin; Spectrometry, Fluorescence | 1998 |
Chemical modification of proteins by methylglyoxal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia | 1998 |
Changes in collagen cross-linking in degenerative disc disease and scoliosis.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dipeptides; Extracellular Matrix; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged; Scoliosis | 1998 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen | 1999 |
Early development of the motor and premotor circuitry of a sexually dimorphic vocal pathway in a teleost fish.
Topics: Aging; Animals; Axonal Transport; Biotin; Embryo, Nonmammalian; Female; Fishes; Lysine; Male; Medulla Oblongata; Motor Neurons; Neural Pathways; Neurons; Rhombencephalon; Sex Characteristics; Swimming; Vocalization, Animal | 1999 |
Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: an avian solution?
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Enzyme Inhibitors; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Hyperglycemia; Leukocytes; Lysine; Oxidative Stress; Random Allocation; Respiratory Burst; Skin; Uric Acid | 1999 |
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Cross-Linking Reagents; Extracellular Matrix; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Osteoarthritis; Proteoglycans; Ribose | 1999 |
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Child; Chronic Disease; Collagen; Cross-Linking Reagents; Humans; Hydroxylation; Hydroxylysine; Lysine; Middle Aged; Rotator Cuff; Tendinopathy | 1999 |
Advanced glycation in D-galactose induced mouse aging model.
Topics: Aging; Animals; Avoidance Learning; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Female; Galactose; Glucose; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Interleukin-2; Learning; Lymphocytes; Lysine; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Nervous System Diseases; Skin; Superoxide Dismutase | 1999 |
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Arginine; Bruch Membrane; Cattle; Choroid Plexus; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Lysine; Middle Aged | 1999 |
Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cataract; Child; Child, Preschool; Chromatography; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Fluorescence; Humans; Imidazoles; Infant; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged | 1999 |
Conversion of lysine to N(epsilon)-(carboxymethyl)lysine increases susceptibility of proteins to metal-catalyzed oxidation.
Topics: Aging; Animals; Catalysis; Cattle; Lysine; Metals; Oxidation-Reduction; Serum Albumin, Bovine | 1999 |
Late embryonic expression of AMPA receptor function in the CA1 region of the intact hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Aging; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Cations, Divalent; Electric Stimulation; Embryonic and Fetal Development; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Hypoxia; Lysine; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Tetrodotoxin | 1999 |
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases | 1999 |
Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus.
Topics: Aging; Animals; Carrier Proteins; Coloring Agents; Electrophysiology; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Lysine; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; N-Methylaspartate; Neurons; Organic Anion Transporters; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Superior Colliculi | 2000 |
Effect of age and menopause on serum concentrations of pentosidine, an advanced glycation end product.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Lysine; Menopause; Middle Aged; Osteocalcin | 2000 |
Accumulation of advanced glycation endproducts in aging male Fischer 344 rats during long-term feeding of various dietary carbohydrates.
Topics: Aging; Animals; Arginine; Blood Glucose; Collagen; Cross-Linking Reagents; Dietary Carbohydrates; Dietary Sucrose; Energy Intake; Fructosamine; Fructose; Glucose; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Inbred F344; Skin; Starch | 2000 |
Carnosine reacts with a glycated protein.
Topics: Aging; Animals; Carnosine; Glycoproteins; Glycosylation; Humans; In Vitro Techniques; Lysine; Ovalbumin; Oxidation-Reduction; Pyruvaldehyde | 2000 |
Effects of adding dietary lysine to a low gluten diet on the brain protein synthesis rate in aged rats.
Topics: Aging; Animals; Body Weight; Brain; Dietary Supplements; Glutens; Lysine; Male; Protein Biosynthesis; Rats; Rats, Wistar; RNA | 2000 |
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Child; Child, Preschool; Collagen; Collagenases; Cross-Linking Reagents; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Skin; Spectrometry, Fluorescence | 2000 |
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins.
Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human | 2000 |
Identification of limiting amino acids in methionine- and lysine-supplemented low-protein diets for turkeys.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Diet, Protein-Restricted; Dietary Supplements; Glycine max; Lysine; Male; Meat; Methionine; Nutritional Requirements; Turkeys; Weight Gain; Zea mays | 2000 |
Interaction between ambient temperature and supplementation of synthetic amino acids on performance and carcass parameters in commercial male turkeys.
Topics: Aging; Amino Acids; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Body Weight; Diet; Eating; Lysine; Male; Meat; Methionine; Temperature; Threonine; Turkeys; Weight Gain | 2000 |
Intestinal transport of monosaccharides and amino acids during postnatal development of mink.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Body Weight; Female; Fructose; Glucose; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Lysine; Male; Methionine; Microvilli; Mink; Monosaccharides; Proline | 2000 |
Isoleucine imbalance using selected mixtures of imbalancing amino acids in diets of the broiler chick.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Composition; Chickens; Diet; Dietary Proteins; Eating; Isoleucine; Lysine; Male; Nutritional Requirements; Regression Analysis; Weight Gain | 2000 |
Neuronal and glial advanced glycation end product [Nepsilon-(carboxymethyl)lysine]] in Alzheimer's disease brains.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Neuroglia; Neurons | 2001 |
Isolation and characterization of senescence-induced cDNAs encoding deoxyhypusine synthase and eucaryotic translation initiation factor 5A from tomato.
Topics: Aging; Amino Acid Sequence; Archaea; Base Sequence; Conserved Sequence; DNA, Complementary; Eukaryotic Translation Initiation Factor 5A; Fungi; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Library; Humans; Lysine; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Plant Leaves; Plant Stems; Plants; Recombinant Proteins; RNA-Binding Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Solanum lycopersicum | 2001 |
Rapid anatomical plasticity of horizontal connections in the developing visual cortex.
Topics: Aging; Animals; Axons; Brain Mapping; Cats; Dominance, Cerebral; Exotropia; Lysine; Neural Pathways; Neuronal Plasticity; Presynaptic Terminals; Pyramidal Cells; Thalamus; Vision, Binocular; Visual Cortex; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2001 |
Accelerated tissue aging and increased oxidative stress in broiler chickens fed allopurinol.
Topics: Aging; Allopurinol; Animals; Antimetabolites; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Glycation End Products, Advanced; Glycosylation; Hemin; Luminescent Measurements; Lysine; Muscle, Skeletal; Oxidative Stress; Skin; Uric Acid | 2001 |
Predominance of late-spiking neurons in layer VI of rat perirhinal cortex.
Topics: Action Potentials; Aging; Animals; In Vitro Techniques; Lysine; Male; Microscopy, Video; Neurons; Parahippocampal Gyrus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Sensory Thresholds | 2001 |
Recurrent CA1 collateral axons in developing rat hippocampus.
Topics: Aging; Animals; Animals, Newborn; Axons; Cell Differentiation; Cell Size; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; GABA Antagonists; Hippocampus; Immunohistochemistry; Lysine; Membrane Potentials; Nerve Net; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunity; Interferon-gamma; Isoproterenol; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysine; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Signal Transduction; Up-Regulation | 2001 |
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chondroitin Sulfate Proteoglycans; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Lectins, C-Type; Lysine; Middle Aged; Osteoarthritis; Proteoglycans | 2001 |
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Arginine; Arthritis, Rheumatoid; Cartilage, Articular; Cattle; Chromatography, High Pressure Liquid; Glycosaminoglycans; Humans; In Vitro Techniques; Knee Joint; Lysine; Matrix Metalloproteinases; Middle Aged; Osteoarthritis, Knee; Phenylmercuric Acetate; Ribose; Synovial Fluid | 2001 |
Cholecystokinin-immunopositive basket and Schaffer collateral-associated interneurones target different domains of pyramidal cells in the CA1 area of the rat hippocampus.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Axons; Calbindins; Cholecystokinin; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Interneurons; Lysine; Male; Neural Inhibition; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Synaptic Transmission | 2002 |
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses | 2002 |
Development of individual axon arbors in a thalamocortical circuit necessary for song learning in zebra finches.
Topics: Aging; Animals; Axons; Cerebral Cortex; Immunohistochemistry; Learning; Lysine; Male; Nerve Net; Neuronal Plasticity; Songbirds; Thalamus; Vocalization, Animal | 2002 |
[Levels of mature cross-links and advanced glycation end product cross-links in human vitreous].
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cross-Linking Reagents; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Vitreous Body | 2002 |
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet.
Topics: Adult; Aging; Diabetes Mellitus; Diet; Diet, Vegetarian; Edible Grain; Enzyme-Linked Immunosorbent Assay; Fabaceae; Fluorescence; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Lysine | 2001 |
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.
Topics: Aging; Animals; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Food Deprivation; Gas Chromatography-Mass Spectrometry; Lysine; Male; Malondialdehyde; Mitochondria; Models, Statistical; Myocardium; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 2002 |
Processing of dietary casein decreases bioavailability of lysine in growing kittens.
Topics: Aging; Animals; Animals, Newborn; Biological Availability; Caseins; Cats; Diet; Lysine | 2002 |
Involvement of Cajal-Retzius cells in robust and layer-specific regeneration of the entorhino-hippocampal pathways.
Topics: Aging; Animals; Animals, Newborn; Axotomy; Body Patterning; Cell Communication; Coculture Techniques; Cues; Entorhinal Cortex; Growth Cones; Growth Substances; Hippocampus; Lysine; Mice; Mice, Inbred Strains; Microscopy, Electron; Nerve Regeneration; Neural Pathways; Neuronal Plasticity; Organ Culture Techniques; Presynaptic Terminals; Pyramidal Cells; Stem Cells | 2002 |
[Hydroxylation of skin collagen in relation to age: analyses of the human skin].
Topics: Adult; Age Factors; Aging; Collagen; Female; Humans; Hydrolysis; Hydroxylation; Hydroxylysine; Hydroxyproline; Lysine; Middle Aged; Proline; Skin | 1977 |
Synthesis of myelin basic proteins in the developing mouse brain.
Topics: Aging; Animals; Brain; Female; Kinetics; Lysine; Male; Mice; Myelin Basic Protein | 1978 |
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine | 1979 |
Age dependence of the biosynthesis of intercellular matrix macromolecules of rabbit aorta in organ culture and cell culture.
Topics: Aging; Animals; Aorta; Cells, Cultured; Desmosine; Elastin; Glucosamine; Glycoproteins; Glycosaminoglycans; Lysine; Macromolecular Substances; Organ Culture Techniques; Rabbits | 1976 |
[Structural and biochemical alterations of human diabetic dermis studied by H-lysine incorporation and microscopy].
Topics: Adolescent; Adult; Aging; Biopsy; Buffers; Calcium Chloride; Child; Collagen; Cytoplasm; Diabetes Mellitus; Elastin; Endoplasmic Reticulum; Fibroblasts; Glycoproteins; Humans; Hydroxyproline; Intercellular Junctions; Lysine; Microbial Collagenase; Pancreatic Elastase; Skin; Tritium; Urea | 1976 |
Age-related changes in function of transfer ribonucleic acid of rat livers.
Topics: Acylation; Aging; Animals; Liver; Lysine; Protein Biosynthesis; Rats; Ribosomes; RNA, Transfer; Serine | 1979 |
Developmental and other characteristics of lysine uptake by rat brain synaptosomes.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Brain; Kinetics; Lysine; Male; Rats; Sodium; Synaptosomes | 1979 |
Biosynthesis of collagen crosslinks in rabbit articular cartilage in vivo.
Topics: Aging; Animals; Cartilage, Articular; Collagen; Cross-Linking Reagents; Lysine; Macromolecular Substances; Rabbits | 1979 |
The nucleosome repeat length increases during erythropoiesis in the chick.
Topics: Aging; Animals; Chick Embryo; Chickens; DNA; Erythroblasts; Erythrocytes; Erythropoiesis; Histones; Leucine; Lysine; Nucleoproteins | 1978 |
Ontogenetic changes in the content of methylated amino acids in rodent skeletal muscle.
Topics: Aging; Animals; Arginine; Cricetinae; Histidine; Lysine; Male; Methylation; Methylhistidines; Mice; Muscle Development; Muscles; Myosins; Rats | 1977 |
Studies on the rat glomerular basement membrane: age-related changes in composition.
Topics: Aging; Amino Acids; Animals; Basement Membrane; Female; Glycine; Hydroxylysine; Hydroxyproline; Kidney Glomerulus; Lysine; Male; Proline; Rats; Sodium Dodecyl Sulfate | 1978 |
The effect of age on amino acid composition of human skin collagen.
Topics: Adult; Age Factors; Aged; Aging; Aldehydes; Amino Acids; Child; Collagen; Cysteine; Female; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Lysine; Middle Aged; Proline; Skin | 1978 |
Age-related changes in the reducible cross-links of human dermis collagen.
Topics: Adult; Age Factors; Aged; Aging; Borohydrides; Child, Preschool; Collagen; Desmosine; Humans; Infant, Newborn; Lysine; Middle Aged; Norleucine; Skin | 1977 |
Aging of human bone and articular cartilage collagen: changes in the reducible cross-links and their precursors.
Topics: Adolescent; Adult; Aged; Aging; Bone and Bones; Cartilage, Articular; Child; Child, Preschool; Collagen; Humans; Leucine; Lysine; Middle Aged; Solubility | 1976 |
[Changes in subfraction composition of chicken lysine-rich histone during ontogenesis].
Topics: Aging; Animals; Brain Chemistry; Chemical Fractionation; Chick Embryo; Chickens; DNA; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Histones; Intestinal Mucosa; Intestine, Small; Liver; Lysine; Male; Myocardium; Organ Size; Testis; Thymus Gland | 1976 |
Decrease in cold tolerance of aged rats caused by the enhanced endogenous adenosine activity.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Body Temperature Regulation; Cold Temperature; Lysine; Male; Neck Muscles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1992 |
Contribution of skin to whole-body protein synthesis in rats at different stages of maturity.
Topics: Aging; Animals; Body Composition; Lysine; Male; Muscle Development; Muscles; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Skin | 1992 |
Developmental changes of L-lysine-ketoglutarate reductase in rat brain and liver.
Topics: Aging; Animals; Brain; Enzyme Induction; Gestational Age; Glucagon; Liver; Lysine; Rats; Rats, Sprague-Dawley; Saccharopine Dehydrogenases; Succinate Dehydrogenase | 1992 |
Developing corticorubral axons of the cat form synapses on filopodial dendritic protrusions.
Topics: Aging; Animals; Axons; Cats; Cerebral Cortex; Dendrites; Histocytochemistry; Lysine; Microscopy, Electron; Synapses | 1992 |
Fluorophores from aging human articular cartilage.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Female; Humans; Lysine; Male; Microbial Collagenase; Middle Aged; Solubility; Spectrometry, Fluorescence | 1991 |
Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen.
Topics: Aging; Collagen; Gas Chromatography-Mass Spectrometry; Glycosylation; Humans; Hydroxylysine; Lens, Crystalline; Lysine; Oxidation-Reduction; Skin | 1991 |
Effect of diabetes and aging on carboxymethyllysine levels in human urine.
Topics: Adolescent; Adult; Aged; Aging; Diabetes Mellitus, Type 1; Humans; Lysine; Middle Aged; Oxidation-Reduction | 1991 |
Change in the amount of epsilon-hexosyllysine, UV absorbance, and fluorescence of collagen with age in different animal species.
Topics: Aging; Animals; Aorta; Cats; Chromatography, Affinity; Collagen; Dogs; Furaldehyde; Glycosylation; Horses; Humans; Lysine; Mice; Skin; Species Specificity; Spectrometry, Fluorescence; Sugar Acids; Thiobarbiturates; Ultraviolet Rays | 1991 |
Change with age of UV absorbance and fluorescence of collagen and accumulation of epsilon-hexosyllysine in collagen from Wistar rats living on different food restriction regimes.
Topics: Aging; Animals; Aorta, Thoracic; Collagen; Food Deprivation; Glycosylation; Hexoses; Longevity; Lysine; Pigmentation; Rats; Rats, Inbred Strains; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1991 |
Alterations of biochemical and biomechanical properties of rat tail tendons caused by non-enzymatic glycation and their inhibition by dibasic amino acids arginine and lysine.
Topics: Aging; Animals; Arginine; Fructosamine; Glucose; Glycosylation; Hexosamines; In Vitro Techniques; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Stress, Mechanical; Tail; Tendons | 1991 |
Collagen in the ageing human intervertebral disc: an increase in covalently bound fluorophores and chromophores.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Color; Cyanogen Bromide; Female; Humans; Hydroxylysine; Intervertebral Disc; Lysine; Middle Aged; Molecular Sequence Data; Papain; Spectrometry, Fluorescence | 1991 |
Analysis of age-associated alteration in the synthesis of HMG nonhistone proteins of the rat liver.
Topics: Aging; Animals; Benzamides; Butyrates; Butyric Acid; Dexamethasone; Electrophoresis, Polyacrylamide Gel; High Mobility Group Proteins; In Vitro Techniques; Liver; Lysine; Male; Rats; Rats, Inbred Strains; Spermine | 1991 |
High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.
Topics: Adult; Aged; Aging; Animals; Arginine; Ascorbic Acid; Cataract; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Crystallins; Humans; Hydrolysis; Lens, Crystalline; Lysine; Models, Biological; Molecular Weight; Pigmentation; Reference Values | 1991 |
Changes with age in the urinary excretion of lysyl- and hydroxylysylpyridinoline, two new markers of bone collagen turnover.
Topics: Adult; Aged; Aging; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Hydrolysis; Hydroxylysine; Lysine; Male; Middle Aged; Pyridinium Compounds; Reference Standards; Reference Values | 1990 |
Age- and diabetes-accelerated glycation in the human aorta.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aorta; Arteriosclerosis; Diabetes Mellitus, Type 2; Female; Humans; Infant, Newborn; Lysine; Maillard Reaction; Male; Middle Aged | 1989 |
[Role of the non-enzymatic glycosylation of protein in the formation of human cataracts].
Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Diabetes Mellitus, Type 2; Eye Proteins; Female; Glycosylation; Humans; Lysine; Male; Middle Aged; Schiff Bases | 1989 |
Glycation of collagen in the aorta and the development of aging.
Topics: Aged; Aging; Animals; Aorta, Abdominal; Collagen; Diabetes Mellitus, Type 2; Fluorescence; Glycosylation; Humans; Lysine; Maillard Reaction; Middle Aged; Rats | 1989 |
Inactivation of erythrocyte Cu-Zn-superoxide dismutase through nonenzymatic glycosylation.
Topics: Adult; Aging; Amino Acids; Enzyme Stability; Erythrocytes; Glycosylation; Hot Temperature; Humans; Hyperglycemia; Lysine; Male; Peptide Mapping; Superoxide Dismutase; Werner Syndrome | 1989 |
Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.
Topics: Aging; Animals; Arginine; Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Histidine; Immunosorbent Techniques; Liver; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1989 |
Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process.
Topics: Aging; Animals; Arginine; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dura Mater; Extracellular Matrix; Hexoses; Humans; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organ Specificity; Pentoses; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1989 |
Oxidation of glycated proteins: age-dependent accumulation of N epsilon-(carboxymethyl)lysine in lens proteins.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography, Ion Exchange; Crystallins; Humans; Infant; Lysine; Middle Aged; Oxidation-Reduction | 1989 |
A study of the age-related acceleration of glycation of tissue proteins in rats.
Topics: Aging; Animals; Aorta; Carbohydrate Metabolism; Chromatography, Affinity; Chromatography, High Pressure Liquid; Fluorescence; Glycated Hemoglobin; Lysine; Male; Proteins; Rats; Rats, Inbred Strains; Specific Pathogen-Free Organisms | 1988 |
Age-related acceleration of glycation of tissue proteins in rats.
Topics: Aging; Animals; Aorta; Glycated Hemoglobin; Glycosylation; Lysine; Male; Rats; Rats, Inbred Strains; Sciatic Nerve | 1986 |
Recovery of age-related decline of thymic endocrine activity and PHA response by lysin-arginine combination.
Topics: Aging; Amino Acids; Animals; Arginine; Cytotoxicity Tests, Immunologic; Lysine; Male; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Thymic Factor, Circulating; Thymus Gland; Thymus Hormones | 1986 |
gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant.
Topics: Adolescent; Adult; Aged; Aging; Betaine; Carnitine; Child, Preschool; Female; gamma-Butyrobetaine Dioxygenase; Humans; Infant; Infant, Newborn; Kidney; Liver; Lysine; Male; Middle Aged; Mixed Function Oxygenases | 1987 |
Chemistry of the collagen cross-links. Origin and partial characterization of a putative mature cross-link of collagen.
Topics: Aging; Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Collagen; Electrophoresis, Paper; In Vitro Techniques; Lysine; Mass Spectrometry; Rabbits; Sheep; Skin | 1987 |
Aging and cross-linking of skin collagen.
Topics: Adult; Aged; Aging; Amino Acids; Animals; Cattle; Collagen; Cross-Linking Reagents; Histidine; Humans; Infant; Lysine; Macromolecular Substances; Norleucine; Skin; Skin Physiological Phenomena | 1988 |
Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.
Topics: Aging; Animals; Arginine; Histidine; Kinetics; Liver; Lysine; Malate Dehydrogenase; Methionine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds | 1988 |
Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats.
Topics: Aging; Amino Acids; Animals; Caseins; Dietary Proteins; Leucine; Lysine; Male; Methylhistidines; Nitrogen; Peptides; Proline; Rats; Rats, Inbred Strains; Tryptophan; Valine | 1988 |
Age-related and diabetes-associated glycation in tissue proteins.
Topics: Aging; Animals; Aorta; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Glycosylation; Lysine; Maillard Reaction; Male; Proteins; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1988 |
Collagen-glycation in the aorta as a developmental factor of aging and arteriosclerosis.
Topics: Aging; Aorta; Arteriosclerosis; Collagen; Diabetes Mellitus, Type 2; Glycosylation; Humans; Lysine; Maillard Reaction; Spectrometry, Fluorescence | 1988 |
Ontogeny modifies manifestations of cystinuria genes: implications for counseling.
Topics: Aging; Amino Acids; Arginine; Cystinuria; Follow-Up Studies; Genetic Counseling; Genotype; Humans; Infant, Newborn; Lysine; Ornithine; Phenotype; Quebec | 1985 |
Protein utilization in growth: effect of lysine deficiency on serum growth hormone, somatomedins, insulin, total thyroxine (T4) and triiodothyronine, free T4 index, and total corticosterone.
Topics: Aging; Animals; Body Weight; Corticosterone; Eating; Growth Hormone; Insulin; Lysine; Male; Proteins; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatomedins; Thyroxine; Triiodothyronine | 1985 |
Turnover of myelin and other structural proteins in the developing rat brain.
Topics: Aging; Animals; Brain; Drug Stability; Electrophoresis, Disc; Glucose; Half-Life; Lysine; Male; Microscopy, Electron; Molecular Weight; Myelin Basic Protein; Myelin Sheath; Nerve Tissue Proteins; Rats; Subcellular Fractions; Time Factors | 1974 |
Beta2-microglobulin: occurrence in fetal life and malignancy.
Topics: Aging; Carbon Radioisotopes; Female; Fetal Proteins; Fetus; Gestational Age; Humans; Immunodiffusion; Infant, Newborn; Infant, Premature; Isoleucine; Leukemia; Lysine; Maternal-Fetal Exchange; Neoplasms; Pregnancy; Serum Globulins; Umbilical Cord | 1974 |
Correlation between a specific isoaccepting lysyl transfer ribonucleic acid and cell division in mammalian tissues.
Topics: Aging; Animals; Bone Marrow; Brain; Carcinoma, Hepatocellular; Cattle; Cell Division; Cells, Cultured; Chromatography, Ion Exchange; Female; Fetus; Lens, Crystalline; Leukemia; Liver; Liver Neoplasms; Lysine; Mice; Neoplasms, Experimental; Organ Specificity; Pancreas; Pregnancy; Rats; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet; Spleen; Swine; Tritium | 1973 |
Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.
Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Chick Embryo; Chickens; Glutamates; Leucyl Aminopeptidase; Lysine; Naphthols; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Sciatic Nerve; Time Factors | 1974 |
Measurements of rates of protein synthesis in rat brain slices.
Topics: Aging; Amino Acids; Animals; Brain; Carbon Radioisotopes; Histidine; In Vitro Techniques; Kinetics; Leucine; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Time Factors; Tritium; Valine | 1974 |
In vivo methylation and turnover of rat brain histones.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Half-Life; Histones; Lysine; Male; Methionine; Methylation; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; Regression Analysis; Time Factors; Tritium | 1974 |
Increased incorporation of 14C-lysine into vascular proteins of the spontaneously hypertensive rat.
Topics: Actomyosin; Aging; Animals; Aorta; Blood Pressure; Blood Proteins; Body Weight; Carbon Radioisotopes; Elastin; Hypertension; Kinetics; Liver; Lysine; Male; Myocardium; Organ Size; Rats; Rats, Inbred Strains; Time Factors | 1974 |
Epsilon-alkyllysinase. New assay method, purification, and biological significance.
Topics: Aging; Animals; Body Weight; Carbon Radioisotopes; Chromatography, Gel; Drug Stability; Freezing; Histones; Hot Temperature; Kidney; Kinetics; Liver; Lysine; Oxidoreductases, N-Demethylating; Polyethylene Glycols; Rats; Time Factors | 1974 |
Further data on the age-dependent intestinal absorption of dibasic amino acids.
Topics: Aging; Amino Acids; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestines; Lysine; Organ Size; Rats | 1974 |
Changes in transfer RNAs and aminoacyl-tRNA synthetases during sea urchin development.
Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Embryo, Nonmammalian; Female; Fertilization; Leucine; Lysine; Ovum; RNA, Transfer; Saccharomyces cerevisiae; Sea Urchins; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
Protein turnover of the lysosomal and mitochondrial fractions of rat liver during aging.
Topics: Aging; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Liver; Lysine; Lysosomes; Male; Microsomes, Liver; Mitochondria, Liver; Proteins; Rats; Tritium | 1972 |
Protein methylase 3 of rat kidney during the early development.
Topics: Aging; Animals; Carbon Radioisotopes; Cell Nucleus; DNA; Female; Fetus; Kidney; Lysine; Methyltransferases; Pregnancy; Proteins; Rats; S-Adenosylmethionine | 1973 |
Protein methylases during the development of rat brain.
Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium | 1973 |
Assay of protocollagen lysyl hydroxylase activity in the skin of human subjects and changes in the activity with age.
Topics: Adolescent; Adult; Aged; Aging; Animals; Carbon Radioisotopes; Chick Embryo; Child; Child, Preschool; Collagen; Female; Fetus; Humans; Hydroxylysine; Infant; Infant, Newborn; Ketoglutaric Acids; Lysine; Middle Aged; Mixed Function Oxygenases; Pregnancy; Protein Precursors; Skin; Subcellular Fractions | 1973 |
Synthesis of type I and type II collagen by embryonic chick cartilage.
Topics: Aging; Animals; Autoradiography; Carbon Radioisotopes; Cartilage; Cartilage, Articular; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Collagen; Hydroxylation; Lysine; Proline; Thymidine; Time Factors; Tritium; Uridine | 1974 |
[Aortic elastin and its variations during senescence and arteriosclerosis].
Topics: Aging; Amino Acids; Animals; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cattle; Elastin; Glutamates; Lysine; Rabbits | 1970 |
Age-related alterations in the structure of nucleoprotein. IV. Changes in the compoistion of whole histone from rat liver.
Topics: Age Factors; Aging; Animals; Arginine; DNA; Edetic Acid; Female; Histones; Immunodiffusion; Liver; Lysine; Methods; Nucleoproteins; Rats; Temperature | 1969 |
Synthesis of aldehydes and their interactions during the in vitro aging of collagen.
Topics: Acetates; Adipates; Aging; Aldehydes; Amines; Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Chemical Phenomena; Chemistry; Collagen; Cysteamine; Edetic Acid; Hot Temperature; In Vitro Techniques; Isoniazid; Lysine; Male; Penicillamine; Rats; Schiff Bases; Skin; Solubility; Tritium | 1971 |
[Distribution of two peptides of -aminobutyric acid in human brain and CSF].
Topics: Adolescent; Adult; Aged; Aging; Aminobutyrates; Brain Chemistry; Cerebral Cortex; Child; Child, Preschool; Chromatography, Ion Exchange; Dipeptides; Histidine; Humans; Infant; Lysine; Middle Aged; Parkinson Disease; Phenylketonurias | 1972 |
Age-related changes in collagen: the identification of reducible lysine-carbohydrate condensation products.
Topics: Aging; Animals; Borohydrides; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Galactose; Glucose; Lysine; Mannitol; Mass Spectrometry; Oxidation-Reduction; Skin; Sugar Alcohols; Tritium | 1972 |
The isolation and partial characterization of age-correlated oligo-deoxyribo-ribonucleotides with covalently linked aspartyl-glutamyl polypeptides.
Topics: Aging; Animals; Aspartic Acid; Brain Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Deoxyribonucleotides; Female; Glutamates; Liver; Lysine; Male; Methods; Molecular Weight; Nucleotides; Peptides; Rats; Spectrophotometry; Spectrum Analysis; Tritium; Ultraviolet Rays | 1972 |
Biochemical studies on the aging of rat tail tendon.
Topics: Aging; Animals; Arginine; Calcium Chloride; Collagen; Fucose; Galactose; Glucose; Glycoproteins; Glycosides; Hexosamines; Hexoses; Hydroxyproline; Lysine; Mannose; Proteins; Rats; Tail; Tendons; Time Factors; Xylose | 1971 |
Protein metabolism in aging mice.
Topics: Aging; Animals; Carbon Isotopes; Injections, Intraperitoneal; Lysine; Male; Mice; Proteins | 1971 |
Is protein catabolism nonrandom?
Topics: Aging; Animals; Carbon Isotopes; Lysine; Male; Mice; Proteins; Starvation; Time Factors | 1971 |
Influence of age on insulin stimulation of amino acid uptake in rat diaphragm.
Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Depression, Chemical; Diaphragm; Drug Antagonism; Extracellular Space; In Vitro Techniques; Insulin; Inulin; Kinetics; Lysine; Male; Models, Biological; Muscle Proteins; Muscles; Puromycin; Rats; Stimulation, Chemical; Time Factors | 1971 |
Some factors influencing the aggregating property of collagen.
Topics: Aging; Animals; Blood Platelets; Carbohydrates; Cattle; Collagen; Humans; Hydroxyproline; Lysine; Organ Specificity; Platelet Adhesiveness; Polymers; Species Specificity; Spectrum Analysis | 1971 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
The influence of endotoxin administration on the nutritional requirements of mice.
Topics: Aging; Amino Acids; Animals; Body Weight; Dietary Proteins; Endotoxins; Escherichia coli; Glutens; Lysine; Methionine; Mice; Nutritional Physiological Phenomena; Threonine; Valine | 1965 |
The heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels.
Topics: Acrylates; Aging; Animals; Brain Chemistry; Cattle; Densitometry; Electrophoresis; Endometrium; Female; Histones; Intestines; Kidney; Liver; Lung; Lysine; Male; Organ Specificity; Sex Factors; Spleen; Sulfides | 1969 |
Effect of concentration on the intestinal absorption of l-lysine in ageing rats.
Topics: Aging; Animals; Carbon Isotopes; Intestinal Absorption; Lysine; Rats | 1969 |
Biosynthesis of collagen fibres.
Topics: Aging; Aspartic Acid; Collagen; Galactose; Glucose; Glutamates; Glycoproteins; Lysine; Proline | 1970 |
Catalytic activities of thermally prepared poly-alpha-amino acids: effect of aging.
Topics: Aging; Biological Evolution; Catalysis; Chemical Phenomena; Chemistry; Hot Temperature; Lysine; Oxaloacetates; Peptides; Phenylacetates; Spectrophotometry; Time Factors | 1970 |
Cerebral amino acid transport in vitro during development: a kinetic analysis.
Topics: Aging; Amino Acids; Aminobutyrates; Animals; Biological Transport; Brain; Brain Chemistry; Chick Embryo; Chickens; Glutamates; In Vitro Techniques; Kinetics; Leucine; Lysine | 1970 |
The biosynthesis of protamine in trout testis. II. Polysome patterns and protein synthetic activities during testis maturation.
Topics: Aging; Animals; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Liver; Lysine; Magnesium; Male; Protamines; Ribonucleases; Ribosomes; Salmonidae; Seasons; Testis; Ultracentrifugation | 1970 |
Putreanine excretion in human urine.
Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autoanalysis; Child; Child, Preschool; Chromatography, Paper; Electrophoresis; Female; Humans; Lysine; Male; Middle Aged; Sex Factors | 1970 |
Effect of ageing on amino acid turnover and rate of protein synthesis in the blowfly Phormia regina.
Topics: Aging; Alanine; Amino Acids; Animals; Carbon Isotopes; Diptera; Lysine; Protein Biosynthesis; Time Factors | 1971 |
Studies on the biosynthesis of the hydroxylysine-linked disaccharide unit of basement membranes and collagens. 3. Tissue and subcellular distribution of glycosyltransferases and the effect of various conditions on the enzyme levels.
Topics: Acetates; Aging; Amino Alcohols; Animals; Animals, Newborn; Basement Membrane; Brain; Carbon Isotopes; Cartilage, Articular; Cell Fractionation; Chromatography, Gel; Chromatography, Paper; Collagen; Diabetes Mellitus, Experimental; Disaccharides; Female; Galactose; Glucosamine; Glucose; Glucosyltransferases; Kidney; Liver; Lysine; Male; Myocardium; Nucleoside Diphosphate Sugars; Organ Specificity; Pregnancy; Rats; Skin; Spleen; Thyroid Gland; Transferases; Uracil Nucleotides; Uterus | 1971 |
Insulin stimulation of amino acid uptake in rat diaphragm. Relationship to protein sythesis.
Topics: Aging; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Isotopes; Cycloheximide; Cycloparaffins; Dactinomycin; Diaphragm; In Vitro Techniques; Insulin; Kinetics; Lysine; Male; Nitrogen; Nucleosides; Oxygen Consumption; Protein Biosynthesis; Puromycin; Rats; Time Factors | 1968 |
Studies on the histones and DNA of calf and old cow thymus.
Topics: Aging; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Cesium; Chromosomes; DNA; Histocytochemistry; Histones; Lysine; Molecular Biology; Spectrophotometry; Thymus Gland | 1968 |
The lens capsule. Sugar and amino acid composition.
Topics: Aging; Amino Acids; Animals; Carbohydrates; Cattle; Collagen; Fucose; Galactose; Glucosamine; Glucose; Glycine; Hexosamines; Hydrogen-Ion Concentration; Hydroxyproline; Kidney Glomerulus; Lens, Crystalline; Lysine; Mannose; Membranes; Neuraminic Acids; Peptides; Proline; Solubility; Uronic Acids; Vibration | 1969 |
Delineation of separate transport systems in rat kidney cortex for L-lysine and L-cystine by developmental patterns.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Carbon Isotopes; Cystine; Kidney; Lysine; Rats; Sodium; Sulfur Isotopes; Tromethamine | 1969 |
[Contribution to the therapeutic study of senescence].
Topics: Aged; Aging; Blood Protein Disorders; Humans; Lysine; Nutrition Disorders; Protein Deficiency | 1964 |
Effect of age and nephrectomy on epsilon-lysine acylase of rat kidney.
Topics: Acid Phosphatase; Aging; Animals; Carboxypeptidases; Kidney; Lysine; Nephrectomy; Rats | 1966 |
Biochemistry of the developing rat brain. 8. Changes in the ribosomal system and nuclear RNA's.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Hydrogen-Ion Concentration; Lysine; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Ultraviolet Rays | 1966 |
[The formation of the feedback inhibition of pancreatic secretion in ontogeny].
Topics: Aging; Amylases; Animals; Depression, Chemical; Dogs; Feedback; Lipase; Pancreas; Pancreatic Juice; Protein Hydrolysates; Secretin; Trypsin | 1990 |