Page last updated: 2024-08-17

lysine and Acute Myelogenous Leukemia

lysine has been researched along with Acute Myelogenous Leukemia in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (16.28)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (18.60)	29.6817
2010's	16 (37.21)	24.3611
2020's	12 (27.91)	2.80

Authors

Authors	Studies
Cooney, J; Hodges, S	1
Acusta, A; Ballas, M; Borthakur, G; Collingwood, T; de la Fuente Burguera, A; Del Buono, H; Dhar, A; Ferron-Brady, G; Karpinich, NO; Kruger, RG; Mohammad, HP; Roboz, GJ; Sanz, G; Verma, A; Wei, AH; Yee, K	1
Casado, P; Cutillas, PR; Gribben, JG; Hijazi, M; Pedicona, F; Rouault-Pierre, K	1
Alikarami, F; Barrett, DR; Bernt, KM; Carroll, M; Chen, CW; Foley, MA; Gardini, A; Hill, C; Huggins, DJ; Kargman, S; Khan, TA; Ladduwahetty, T; Li, H; Li, Q; Li, Y; Liu, Y; Liverton, N; Mahdavi, L; Maillard, I; Meinke, PT; Michino, M; Pokharel, SP; Renzetti, LM; Shi, J; Song, L; Stamford, AW; Tang, S; Taylor, S; Wan, L; Watt, GF; Yang, L	1
Crunkhorn, S	1
Amatori, S; Bonaldi, T; Cantatore, F; Casciaro, F; Errico Provenzano, A; Fanelli, M; Formica, M; Fusi, V; Gambardella, S; Giorgi, L; Giorgio, M; Macedi, E; Noberini, R; Persico, G; Rusin, M	1
Beckedorff, F; Duffort, S; Figueroa, M; Greenblatt, S; Karl, D; Lai, F; Liu, F; Man, N; Martin, GM; Martinez, C; Martinez, CJ; Nimer, S; Roisman, A; Shiekhattar, R; Sun, J; Sun, X; Wang, L; Xu, Y; Yue, J	1
Aa, J; Cao, B; Li, J; Wang, Q; Zheng, M; Zhou, X	1
Chen, TQ; Chen, YQ; Fang, K; Han, C; Huang, W; Luo, XQ; Pan, Q; Sun, LY; Sun, YM; Wang, D; Wang, WT; Yang, QQ; Zeng, ZC	1
Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W	1
Hu, H; Muntean, AG; Peterson, LF; Ropa, J; Saha, N; Talpaz, M	1
Ahmann, JM; Andersen, JL; Antelope, O; Clair, PM; Cox, JE; D'Alessandro, A; Deininger, MW; Egbert, CM; Franzini, A; Gantz, KC; Halverson, BJ; Heaton, WL; Iyer, SM; Jones, CL; Khorashad, JS; Mason, CC; O'Hare, T; Olsen, CA; Owen, SC; Patel, AB; Pomicter, AD; Rajabi, N; Redwine, HM; Reisz, JA; Senina, AV; Than, H; van Scoyk, A; Vellore, NA; Xiao, MJ; Yan, D; Zabriskie, MS	1
Arellano, M; Blum, WG; Boggon, TJ; Chen, D; Chen, J; Dong, L; Elf, SE; Famulare, CA; Fan, H; Gao, X; He, C; Le Beau, M; Levine, RL; Li, Y; Lonial, S; Mao, H; Odenike, O; Stock, W; Su, R; Wang, M; Wu, R; Xia, S; Zhang, R; Zhu, AC	1
Chen, S; Chen, X; Greenblatt, S; Guo, Y; Guo, Z; He, F; Li, J; Li, Z; Man, N; Morey, L; Nimer, SD; Shi, H; Sun, Y; Wang, L; Wang, QF; Wang, QT; Williams, S; Xu, M; Yang, FC; Yang, H; Yu, P; Zhang, P; Zhou, Y	1
Barosi, G; Campanelli, R; Catarsi, P; Massa, M; Poletto, V; Rosti, V; Vannucchi, AM; Villani, L	1
Jordan, AM; McGonagle, AE; Mould, DP; Williams, EL; Wiseman, DH	1
Ikezoe, T; Nishioka, C; Yang, J; Yokoyama, A	1
Cheng, Z; Hao, Y; Liu, H; Liu, N; Liu, X; Peng, X; Qi, W; Sun, Z; Wang, F; Wu, Q; Xu, L; Yan, J; Zheng, N; Zhu, J; Zhu, X	1
Andreeff, M; Campbell, CT; Chevassut, T; Daigle, SR; Deng, L; Goodell, MA; Jeong, M; Kornblau, SM; Li, W; Luo, M; Rau, RE; Rodriguez, BA; Rogers, JH; Rosen, A; Song, Y; Sweet, S	1
Allis, CD; Armstrong, SA; Bradner, JE; Erb, MA; Hoshii, T; Joseph, JK; Li, H; Li, W; Li, Y; Loh, YE; Lyu, J; Shen, L; Shi, X; Souza, AL; Wan, L; Wang, X; Wen, H; Xi, Y	1
Ai, J; Avalos, BR; Druhan, LJ; Loveland, MJ	1
Armstrong, SA; Bracken, AP; Faber, J; Feng, Z; Jesneck, J; Krivtsov, AV; Kung, AL; Kutok, JL; Lemieux, ME; Silverman, LB; Sinha, AU; Vempati, S; Xia, X	1
Frankel, AE; Ghosh, S; Hogge, DE; Li, SY; Ortiz, J; Su, Y	1
Bies, J; Paul, TA; Small, D; Wolff, L	1
Agrawal-Singh, S; Becker, A; Berdel, WE; Disselhoff, C; Dugas, M; Ehninger, G; Hascher, A; Isken, F; Klein, HU; Koschmieder, S; McClelland, M; Müller, FU; Müller-Tidow, C; Schlenke, P; Schmitz, W; Seidl, M; Serve, H; Thiede, C; Thoennissen, N; Tickenbrock, L; Tschanter, P; Wang, Y; zur Stadt, U	1
Asai, T; Cole, PA; Deblasio, T; Gural, A; Hatlen, MA; Huang, G; Jiang, Y; Liu, F; Melnick, A; Menendez, S; Nimer, SD; Perna, F; Roeder, RG; Sun, XJ; Voza, F; Vu, L; Wang, L; Xu, H; Zhang, J; Zhao, X	1
Burnett, A; Casero, RA; Chen, WC; Dick, JE; Dugas, M; Göllner, S; Hebestreit, K; Howell, L; Jin, L; Klein, HU; Marton, L; Mills, K; Minden, MD; Müller-Tidow, C; Petrie, K; Popescu, AC; Schenk, T; Wang, JC; Woster, P; Zelent, A	1
Armstrong, SA; Beverloo, HB; Bindels, EM; Delwel, R; Döhner, H; Erpelinck, C; Haanstra, JR; Havermans, M; Hudson, WA; Kersey, JH; Krivtsov, AV; Kumar, AR; Lugthart, S; Rombouts, E; Taskesen, E; Wocjtowicz, E	1
Jevdjovic, T; Meenhuis, A; Palande, K; Touw, IP	1
Barbetti, V; Cheloni, G; Dello Sbarba, P; Fabiani, E; Gozzini, A; Marzi, I; Rovida, E; Santini, V	1
Karakus, S; Seftalioglu, A	1
Lin, D; Liu, X; Rao, Q; Tian, Z; Wang, J; Wang, M; Yu, W	1
Anensen, N; Bruserud, Ø; Gjertsen, BT; Ryningen, A; Stapnes, C; Tronstad, KJ	1
Jing, N; Shao, H; Tweardy, DJ; Xu, X	1
Freitas, MA; Knapp, AR; Liu, S; Marcucci, G; Parthun, MR; Su, X; Zhang, L	1
Balkhi, MY; Behre, G; Christopeit, M; Geletu, M; Peer Zada, AA; Pulikkan, JA; Tenen, DG; Trivedi, AK	1
Hansz, J	1
Kass, L	1
Lippman, ME; Perry, S; Thompson, EB	1
Iavorkovskiĭ, LI; Poddubnaia, EV	1
Beebe, DP; Faguet, GB	1
Caen, J; Janneau, C; Lukasiewicz, H; Vainer, H	1
Hersh, EM; Ohno, R	1

Reviews

3 review(s) available for lysine and Acute Myelogenous Leukemia

Article	Year
Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date. Medicinal research reviews, 2015, Volume: 35, Issue:3 Topics: Animals; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone Demethylases; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Lysine; Mice; Polyamines; Treatment Outcome	2015
Scratching the surface: signaling and routing dynamics of the CSF3 receptor. Frontiers in bioscience (Landmark edition), 2013, 01-01, Volume: 18, Issue:1 Topics: Animals; Congenital Bone Marrow Failure Syndromes; Endocytosis; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Humans; Janus Kinases; Leukemia, Myeloid, Acute; Lysine; Lysosomes; Mice; Neutropenia; Oxidation-Reduction; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Receptors, Colony-Stimulating Factor; Signal Transduction; Ubiquitin Thiolesterase; Ubiquitination	2013
Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. Expert opinion on therapeutic targets, 2006, Volume: 10, Issue:1 Topics: Acetylation; Adult; Antineoplastic Agents; Drug Delivery Systems; Enzyme Inhibitors; Hematopoiesis; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leukemia, Myeloid, Acute; Lysine	2006

Trials

1 trial(s) available for lysine and Acute Myelogenous Leukemia

Article	Year
Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes. Leukemia & lymphoma, 2022, Volume: 63, Issue:2 Topics: Benzoates; Cyclopropanes; Humans; Leukemia, Myeloid, Acute; Lysine; Myelodysplastic Syndromes	2022

Other Studies

39 other study(ies) available for lysine and Acute Myelogenous Leukemia

Article	Year
Novel lysine-specific histone demethylase 1 inhibitor in acute myeloid leukaemia transformed from essential thrombocythaemia. Cancer reports (Hoboken, N.J.), 2022, Volume: 5, Issue:8 Topics: Aged; Enzyme Inhibitors; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Thrombocythemia, Essential	2022
Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment. Science signaling, 2022, 04-19, Volume: 15, Issue:730 Topics: Antineoplastic Agents; Cell Line, Tumor; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors	2022
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia. Cancer discovery, 2022, 11-02, Volume: 12, Issue:11 Topics: Chromatin; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Myeloid-Lymphoid Leukemia Protein	2022
Acyl-lysine reader inhibitor blocks AML progression. Nature reviews. Drug discovery, 2022, Volume: 21, Issue:11 Topics: Histones; Humans; Leukemia, Myeloid, Acute; Lysine	2022
Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation. Cancer gene therapy, 2023, Volume: 30, Issue:5 Topics: Antiviral Agents; Cell Differentiation; Down-Regulation; Epigenomics; Histones; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lysine; Oncogene Proteins, Fusion	2023
TAF1 plays a critical role in AML1-ETO driven leukemogenesis. Nature communications, 2019, 10-29, Volume: 10, Issue:1 Topics: Acetylation; Animals; Carcinogenesis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Chromatin; Core Binding Factor Alpha 2 Subunit; Gene Expression Regulation, Leukemic; Histone Acetyltransferases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice, Inbred C57BL; Myeloid Cells; Oncogene Proteins, Fusion; Protein Binding; Protein Domains; RUNX1 Translocation Partner 1 Protein; TATA-Binding Protein Associated Factors; Transcription Factor TFIID	2019
Metabolomics analysis identifies lysine and taurine as candidate prognostic biomarkers for AML-M2 patients. International journal of hematology, 2020, Volume: 111, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Humans; Leukemia, Myeloid, Acute; Lysine; Male; Metabolomics; Middle Aged; Mutation; Prognosis; Risk; Taurine; Young Adult	2020
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia. Journal of hematology & oncology, 2020, 06-17, Volume: 13, Issue:1 Topics: Animals; Cell Self Renewal; Child, Preschool; Female; Gene Expression Regulation, Leukemic; Genetic Vectors; Heterografts; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Infant; Leukemia, Myeloid, Acute; Lysine; Lysosomal Membrane Proteins; Male; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA Interference; RNA, Antisense; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Specific Pathogen-Free Organisms; Tumor Cells, Cultured; Tumor Stem Cell Assay	2020
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia. Oncogene, 2020, Volume: 39, Issue:50 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic	2020
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation. Haematologica, 2020, 09-01, Volume: 105, Issue:9 Topics: Animals; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion	2020
SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA. Blood cancer discovery, 2021, Volume: 2, Issue:3 Topics: Apoptosis; Humans; Leukemia, Myeloid, Acute; Lysine; Mitochondria; Oxidative Phosphorylation; Sirtuins	2021
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Molecular cell, 2021, 09-16, Volume: 81, Issue:18 Topics: Acetyl-CoA C-Acetyltransferase; Acetylation; Animals; Antineoplastic Agents; Female; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Leukemia, Myeloid, Acute; Lysine; Male; Mice; Mice, Inbred NOD; Mutation; NADP; Nuclear Proteins; Phosphorylation; Polymorphism, Single Nucleotide; Primary Cell Culture; Protein Binding; Protein Processing, Post-Translational; Protein-Tyrosine Kinases	2021
Loss of Asxl2 leads to myeloid malignancies in mice. Nature communications, 2017, 06-08, Volume: 8 Topics: Animals; Cell Lineage; Cell Self Renewal; Disease Progression; Gene Deletion; Gene Expression Regulation, Leukemic; Hematopoiesis; Hematopoietic Stem Cells; Histones; Leukemia, Myeloid, Acute; Lysine; Mice; Myelodysplastic Syndromes; Myeloid Cells; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic	2017
No association between the XPD Lys751Gln (rs13181) polymorphism and disease phenotype or leukemic transformation in primary myelofibrosis. Haematologica, 2013, Volume: 98, Issue:8 Topics: Cell Transformation, Neoplastic; Cohort Studies; Genetic Variation; Glutamine; Humans; Leukemia, Myeloid, Acute; Lysine; Phenotype; Polymorphism, Genetic; Primary Myelofibrosis; Xeroderma Pigmentosum Group D Protein	2013
Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells. PloS one, 2015, Volume: 10, Issue:5 Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; Cell Line, Tumor; DNA Methylation; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Enzyme Activation; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Histones; Humans; Kangai-1 Protein; Leukemia, Myeloid, Acute; Lysine; Male; MAP Kinase Signaling System; Models, Biological; p38 Mitogen-Activated Protein Kinases; Polycomb Repressive Complex 2; Polymerase Chain Reaction; Promoter Regions, Genetic; PTEN Phosphohydrolase; RNA, Small Interfering	2015
Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells. Scientific reports, 2016, Jan-29, Volume: 6 Topics: Acetylation; Amino Acid Motifs; Amino Acid Sequence; Cluster Analysis; Computational Biology; HL-60 Cells; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Lysine; Position-Specific Scoring Matrices; Protein Interaction Mapping; Protein Interaction Maps; Proteome; Proteomics; Valproic Acid; Vorinostat	2016
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood, 2016, 08-18, Volume: 128, Issue:7 Topics: Adenosine; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice, Inbred C57BL; Molecular Targeted Therapy; Mutation; Phenylurea Compounds; Rats; Time Factors; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays	2016
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature, 2017, 03-09, Volume: 543, Issue:7644 Topics: Acetylation; Animals; Cell Line, Tumor; CRISPR-Cas Systems; Epigenesis, Genetic; Female; Gene Editing; Gene Expression Regulation, Neoplastic; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Oncogenes; Promoter Regions, Genetic; Protein Binding; Protein Domains; RNA Polymerase II; Transcription, Genetic; Transcriptional Elongation Factors	2017
G-CSFR ubiquitination critically regulates myeloid cell survival and proliferation. PloS one, 2008, Volume: 3, Issue:10 Topics: Cell Proliferation; Cell Survival; Humans; Leukemia, Myeloid, Acute; Lysine; Mutant Proteins; Myeloid Cells; Neutropenia; Receptors, Granulocyte Colony-Stimulating Factor; Ubiquitination	2008
H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer cell, 2008, Nov-04, Volume: 14, Issue:5 Topics: Animals; Biomarkers, Tumor; Cell Differentiation; Cells, Cultured; Chromatin Immunoprecipitation; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Rearrangement; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Immunophenotyping; Integrases; Leukemia, Myeloid, Acute; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Transgenic; Myeloid-Lymphoid Leukemia Protein; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Principal Component Analysis; Protein Methyltransferases; RNA, Small Interfering; Transcription, Genetic	2008
Characterization of variant diphtheria toxin-interleukin-3 fusion protein, DTIL3K116W, for phase I clinical trials. Biologicals : journal of the International Association of Biological Standardization, 2010, Volume: 38, Issue:1 Topics: Amino Acid Substitution; Bone Marrow Cells; Cells, Cultured; Clinical Trials, Phase I as Topic; Diphtheria Toxin; Drug Compounding; Drug Contamination; Drug Evaluation, Preclinical; Drug Stability; Genetic Variation; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Lysine; Recombinant Fusion Proteins; Sterilization; Toxicity Tests; Tryptophan	2010
Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML. Blood, 2010, Apr-15, Volume: 115, Issue:15 Topics: Blast Crisis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Genetic Loci; Histone Deacetylase Inhibitors; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Transcription Factors	2010
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia. Blood, 2010, Nov-04, Volume: 116, Issue:18 Topics: Adolescent; Antigens, CD34; Child; Child, Preschool; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histones; Humans; Infant; Leukemia, Myeloid, Acute; Lysine; Male; Methylation; Prognosis; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Tumor Cells, Cultured	2010
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (New York, N.Y.), 2011, Aug-05, Volume: 333, Issue:6043 Topics: Acetylation; Animals; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Core Binding Factor Alpha 2 Subunit; E1A-Associated p300 Protein; Fetal Blood; Gene Expression Profiling; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred C57BL; Mutant Proteins; Oncogene Proteins, Fusion; Preleukemia; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; RUNX1 Translocation Partner 1 Protein; Transcriptional Activation; Tumor Cells, Cultured	2011
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nature medicine, 2012, Mar-11, Volume: 18, Issue:4 Topics: Animals; Antigens, CD34; Apoptosis; CD11b Antigen; Cell Differentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Female; Flow Cytometry; Gene Expression Regulation; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Lysine; Mice; Mice, Inbred NOD; Mice, SCID; RNA, Small Interfering; Stem Cell Factor; Time Factors; Transplants; Tranylcypromine; Tretinoin	2012
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs. Blood, 2012, Jun-14, Volume: 119, Issue:24 Topics: Animals; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Colony-Forming Units Assay; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Gene Rearrangement; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; MDS1 and EVI1 Complex Locus Protein; Mice; Mice, Inbred C57BL; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Transcription Factors	2012
Time- and residue-specific differences in histone acetylation induced by VPA and SAHA in AML1/ETO-positive leukemia cells. Epigenetics, 2013, Volume: 8, Issue:2 Topics: Acetylation; Apoptosis; Cell Differentiation; Core Binding Factor Alpha 2 Subunit; Gene Expression Regulation, Leukemic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Lysine; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Time Factors; Transcription Factors; Valproic Acid; Vorinostat	2013
Syndecan-1/CD138 expression in normal myeloid, acute lymphoblastic and myeloblastic leukemia cells. Acta histochemica, 2003, Volume: 105, Issue:3 Topics: Acute Disease; Adult; Antibodies, Monoclonal; Cell Membrane; Formaldehyde; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Membrane Glycoproteins; Microscopy, Immunoelectron; Middle Aged; Myeloid Cells; Periodic Acid; Proteoglycans; Syndecan-1; Syndecans	2003
The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level. Leukemia research, 2006, Volume: 30, Issue:5 Topics: Apoptosis; Asparagine; Benzoquinones; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia, Myeloid, Acute; Lysine; Mutation; Proto-Oncogene Proteins c-kit; RNA, Messenger; Time Factors; Tumor Cells, Cultured	2006
Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. Journal of immunology (Baltimore, Md. : 1950), 2006, Mar-01, Volume: 176, Issue:5 Topics: Arginine; Cell Line; Computational Biology; Glutamic Acid; Humans; Leukemia, Myeloid, Acute; Ligands; Lysine; Models, Molecular; Phosphopeptides; Phosphotyrosine; Protein Binding; Receptors, Granulocyte Colony-Stimulating Factor; STAT3 Transcription Factor	2006
Histone H4 N-terminal acetylation in Kasumi-1 cells treated with depsipeptide determined by acetic acid-urea polyacrylamide gel electrophoresis, amino acid coded mass tagging, and mass spectrometry. Journal of proteome research, 2007, Volume: 6, Issue:1 Topics: Acetic Acid; Acetylation; Cell Line; Cell Line, Tumor; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Histone Deacetylases; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Mass Spectrometry; Protein Processing, Post-Translational; Urea	2007
Target proteins of C/EBPalphap30 in AML: C/EBPalphap30 enhances sumoylation of C/EBPalphap42 via up-regulation of Ubc9. Blood, 2007, Nov-01, Volume: 110, Issue:9 Topics: CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Gene Expression Regulation, Leukemic; Gene Silencing; Genes, Dominant; Granulocytes; Humans; K562 Cells; Leukemia, Myeloid, Acute; Lysine; Models, Biological; Mutant Proteins; Protein Isoforms; Protein Processing, Post-Translational; Receptors, Estrogen; SUMO-1 Protein; Transcriptional Activation; Ubiquitin-Conjugating Enzymes; Up-Regulation	2007
[Lysine metabolism in acute leukemia]. Acta haematologica Polonica, 1979, Volume: 10, Issue:4 Topics: Adolescent; Adult; Carbon Dioxide; Carbon Radioisotopes; Female; Granulocytes; Humans; Isotope Labeling; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lipids; Lymphocytes; Lysine; Male; Middle Aged; Nucleotides	1979
Histone abnormalities in adult acute leukemias. Blood, 1975, Volume: 45, Issue:4 Topics: Adult; Arginine; Electrophoresis, Disc; Esterases; Hematopoietic Stem Cells; Histones; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Monocytes	1975
Glucocorticoid binding proteins in myeloblasts of acute myelogenous leukemia. The American journal of medicine, 1975, Volume: 59, Issue:2 Topics: Bone Marrow; Bone Marrow Cells; Cytoplasm; Cytosol; Dexamethasone; DNA, Neoplasm; Glucocorticoids; Humans; Leukemia, Myeloid, Acute; Lysine; Protein Binding; Proteins; Receptors, Drug; Steroids; Thymidine; Trichloroacetic Acid; Uridine	1975
[Change in the fractional composition of the histones of leukocytes in various forms of leukemia]. Problemy gematologii i perelivaniia krovi, 1975, Volume: 20, Issue:10 Topics: Granulocytes; Histones; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lysine	1975
Nutritional requirements of human malignant (leukemic) cell lines: implications for adjuvant therapy. Cancer research, 1987, May-01, Volume: 47, Issue:9 Topics: Amino Acids; Cell Division; Cells, Cultured; Culture Media; DNA Replication; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lysine	1987
Biosynthetic activities in normal and pathological platelet populations. Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53 Topics: Adenosine; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cell Survival; Centrifugation, Density Gradient; Epinephrine; Glutamates; Glycogen; Glycogen Synthase; Histocompatibility Antigens; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Platelet Adhesiveness; Prostaglandins; Purpura, Thrombocytopenic; Thrombin; Thrombocytopenia	1972
Immunosuppressive effects of L-asparaginase. Cancer research, 1970, Volume: 30, Issue:6 Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine	1970