Page last updated: 2024-08-17

lysine and ALS - Amyotrophic Lateral Sclerosis

lysine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's10 (40.00)29.6817
2010's6 (24.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Kang, YS; Latif, S1
Buratti, E; Elsässer, SJ; Feederle, R; Garcia Morato, J; Gloeckner, CJ; Hans, F; Kahle, PJ; Neumann, M; Skodras, AA; von Zweydorf, F1
Arenas, A; Barnett, KR; Chen, J; Gal, J; Kasarskis, EJ; Kuang, L; Zhu, H1
Chen, S; Chen, Z; Cui, F; Huang, X; Li, Y; Ling, L; Ren, Y; Sun, B; Yang, F1
Cohen, TJ; Hwang, AW; Lee, VM; Restrepo, CR; Trojanowski, JQ; Yuan, CX1
Ball, LE; Comte-Walters, S; Harlan, BA; Neely, BA; Pehar, M; Sharma, DR; Vargas, MR1
Gourie-Devi, M; Kukreti, R; Ramachandran, S; Taneja, B; Taneja, V; Vats, A; Verma, M1
Kamishina, H; Kato, S; Kobatake, Y; Kohyama, M; Maeda, S; Sakai, H; Sasaki, J; Tsukui, T; Urushitani, M; Yamato, O1
Baas, F; Bourque, PR; Diekstra, FP; Hennekam, EA; Lindhout, D; Ophoff, RA; Schelhaas, HJ; Strengman, E; van den Berg, LH; van Es, MA; Veldink, JH1
Gordon, T; Hegedus, J; Jones, KE1
Ashley, J; Bilgicer, B; Borchelt, DR; Hentz, M; Mowery, RA; Ramirez, AJ; Shaw, BF; Shi, Y; Slunt-Brown, H1
Kikuchi, S; Makita, Z; Ogata, A; Shinpo, K; Takeuchi, M; Tashiro, K; Tsuji, S1
Boehm, BO; Kaufmann, E; Kientsch-Engel, R; Ludolph, AC; Sperfeld, A; Süssmuth, SD; Tumani, H1
Horiuchi, S; Kawaguchi, M; Kobayashi, M; Shibata, N1
Hanemann, CO; Krause, BJ; Ludolph, AC; Meyer, T; Münch, C; Reske, S; Rosenbohm, A; Sedlmeier, R; Sperfeld, AD; Stumm, G; Uttner, I1
Beck, M; Sendtner, M; Toyka, KV1
Gralla, EB; Nishida, CR; Valentine, JS1
Gamonet, F; Lauquin, GJ1
Barnéoud, P; Curet, O1
Asayama, K; Hirano, A; Horiuchi, S; Kato, S; Kobayashi, M; Komori, T; Nagai, R; Shibata, N; Umahara, T1
Asayama, K; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Nakano, I; Nakashima, K; Ohama, E; Saito, M; Shibata, N1
Fujii, J; Kikuchi, S; Moriwaka, F; Ogata, A; Shinpo, K; Taniguchi, N; Tashiro, K1
Asayama, K; Hirano, A; Horiuchi, S; Jono, T; Kato, S; Kobayashi, M; Miyata, S; Nagai, R; Sasaki, S; Shibata, N1
Cleveland, DW; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Liu, J; Nagai, R; Nakano, I; Nakashima, K; Ohama, E; Shibata, N; Takikawa, M1
Bunch, LD; Poser, CM1

Other Studies

25 other study(ies) available for lysine and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
Differences of Transport Activity of Arginine and Regulation on Neuronal Nitric Oxide Synthase and Oxidative Stress in Amyotrophic Lateral Sclerosis Model Cell Lines.
    Cells, 2021, 12-16, Volume: 10, Issue:12

    Topics: Amino Acid Transport Systems, Basic; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Line; Gene Expression Regulation; Humans; Hydrogen Peroxide; Lysine; Mice; Motor Neurons; Nitric Oxide Synthase Type I; Oxidative Stress; Spinal Cord; Superoxide Dismutase-1

2021
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43.
    Nature communications, 2022, 03-09, Volume: 13, Issue:1

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Humans; Lysine; Protein Aggregation, Pathological; Protein Processing, Post-Translational; RNA; Sirtuin 1

2022
Lysine acetylation regulates the RNA binding, subcellular localization and inclusion formation of FUS.
    Human molecular genetics, 2020, 09-29, Volume: 29, Issue:16

    Topics: Acetylation; Adult; Amyotrophic Lateral Sclerosis; beta Karyopherins; Female; Frontotemporal Dementia; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Male; Middle Aged; Nuclear Localization Signals; Protein Domains; RNA-Binding Protein FUS; RNA-Binding Proteins; Sirtuins; Young Adult

2020
A novel D90_K91insN mutation in exon 4 of the SOD1 gene caused familial amyotrophic lateral sclerosis in a Chinese pedigree.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2018, Volume: 19, Issue:7-8

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Asparagine; Computational Biology; DNA Mutational Analysis; Exons; Humans; Lysine; Male; Middle Aged; Models, Molecular; Mutation; Pediatrics; Superoxide Dismutase-1

2018
An acetylation switch controls TDP-43 function and aggregation propensity.
    Nature communications, 2015, Jan-05, Volume: 6

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Frontotemporal Lobar Degeneration; Humans; Immunohistochemistry; Immunoprecipitation; Lysine; Mass Spectrometry; Mutagenesis, Site-Directed; Oxidative Stress; Protein Aggregation, Pathological; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spinal Cord

2015
Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:2

    Topics: Acetylation; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Disease Models, Animal; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; Lysine; Mice; Mice, Knockout; Neurons; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Reactive Oxygen Species

2016
Identification of L84F mutation with a novel nucleotide change c.255G > T in the superoxide dismutase gene in a North Indian family with amyotrophic lateral sclerosis.
    Amyotrophic lateral sclerosis & frontotemporal degeneration, 2016, Volume: 17, Issue:3-4

    Topics: Aged; Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Family Health; Female; Genetic Testing; Genotype; Humans; India; Lysine; Male; Middle Aged; Models, Molecular; Phenylalanine; Polymorphism, Single Nucleotide; Superoxide Dismutase-1

2016
Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy.
    Journal of the neurological sciences, 2017, Jan-15, Volume: 372

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies; Calcium-Binding Proteins; Disease Models, Animal; DNA-Binding Proteins; Dogs; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; HEK293 Cells; Humans; Immunoprecipitation; Lysine; Microfilament Proteins; Mutation; Spinal Cord; Superoxide Dismutase-1; Transfection

2017
A case of ALS-FTD in a large FALS pedigree with a K17I ANG mutation.
    Neurology, 2009, Jan-20, Volume: 72, Issue:3

    Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Base Sequence; Dementia; Female; Heterozygote; Humans; Isoleucine; Lysine; Male; Middle Aged; Mutation; Pedigree; Ribonuclease, Pancreatic

2009
Development and use of the incremental twitch subtraction MUNE method in mice.
    Supplements to Clinical neurophysiology, 2009, Volume: 60

    Topics: Action Potentials; Alanine; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Electric Stimulation; Electromyography; Isometric Contraction; Lysine; Male; Mice; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors

2009
Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding.
    Protein science : a publication of the Protein Society, 2012, Volume: 21, Issue:8

    Topics: Acetylation; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Mice; Motion; Mutant Proteins; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Superoxide Dismutase; Superoxide Dismutase-1; Surface-Active Agents

2012
Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cord.
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2002, Volume: 3, Issue:2

    Topics: Aged; Amyotrophic Lateral Sclerosis; Autopsy; Axons; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Neurons; Spinal Cord

2002
The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.
    Neuroscience letters, 2004, Nov-23, Volume: 371, Issue:2-3

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Statistics, Nonparametric

2004
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2005, Volume: 25, Issue:1

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glyoxal; Immunoblotting; Immunohistochemistry; Lysine; Rats

2005
Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.
    Annals of neurology, 2005, Volume: 58, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Arginine; Dementia; DNA Mutational Analysis; Dynactin Complex; Family Health; Female; Humans; Lysine; Magnetic Resonance Imaging; Male; Microtubule-Associated Proteins; Middle Aged; Mutation

2005
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
    Muscle & nerve, 2007, Volume: 36, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Asparagine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Lysine; Middle Aged; Mutation; Phenotype; Superoxide Dismutase; Superoxide Dismutase-1

2007
Characterization of three yeast copper-zinc superoxide dismutase mutants analogous to those coded for in familial amyotrophic lateral sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: Alanine; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Arginine; Edetic Acid; Glycine; Humans; Kinetics; Lysine; Mutagenesis; Paraquat; Point Mutation; Saccharomyces cerevisiae; Spectrophotometry; Superoxide Dismutase

1994
The Saccharomyces cerevisiae LYS7 gene is involved in oxidative stress protection.
    European journal of biochemistry, 1998, Feb-01, Volume: 251, Issue:3

    Topics: Alleles; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Copper; Cytosol; Fungal Proteins; Humans; Isoenzymes; Lysine; Methionine; Mitochondria; Molecular Chaperones; Molecular Sequence Data; Oxidative Stress; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Superoxide Dismutase; Superoxides

1998
Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis.
    Experimental neurology, 1999, Volume: 155, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; Brain; Humans; Lysine; Male; Mice; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Mutation; Postural Balance; Reflex; Salicylates; Solubility; Superoxide Dismutase

1999
Advanced glycation endproducts are deposited in neuronal hyaline inclusions: a study on familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
    Acta neuropathologica, 1999, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Antibodies; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Motor Neurons; Neurofilament Proteins; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins

1999
Astrocytic hyaline inclusions contain advanced glycation endproducts in familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation: immunohistochemical and immunoelectron microscopical analyses.
    Acta neuropathologica, 1999, Volume: 97, Issue:3

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Astrocytes; Cytoplasmic Granules; Female; Glycation End Products, Advanced; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Lewy Bodies; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Mutation; Neurofibrils; Neurons; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitins

1999
Detection of an Amadori product, 1-hexitol-lysine, in the anterior horn of the amyotrophic lateral sclerosis and spinobulbar muscular atrophy spinal cord: evidence for early involvement of glycation in motoneuron diseases.
    Acta neuropathologica, 2000, Volume: 99, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Atrophy; Axons; Glycosylation; Humans; Lysine; Muscular Disorders, Atrophic; Neurons; Spinal Cord; Time Factors

2000
Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Aged; Aldehydes; Amyotrophic Lateral Sclerosis; Arginine; Deoxyguanosine; Glycosylation; Humans; Imidazoles; Lipid Peroxidation; Lysine; Male; Middle Aged; Motor Neurons; Oxidative Stress; Spinal Cord; Superoxide Dismutase

2000
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Animals; Arginine; Female; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Immunoelectron; Middle Aged; Mutation; Norleucine; Pyrroles; Superoxide Dismutase; Superoxide Dismutase-1

2000
Serum amino acid studies in amyotrophic lateral sclerosis. II. Results of metrecal arginine lysine tolerance tests in US caucasians and Guam Chamorros.
    Archives of neurology, 1966, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Amyotrophic Lateral Sclerosis; Arginine; Blood Chemical Analysis; Chromatography; Humans; Lysine; Male; Middle Aged; Pacific Islands; United States; White People

1966