Page last updated: 2024-11-06

lysergic acid diethylamide and Serotonin Syndrome

lysergic acid diethylamide has been researched along with Serotonin Syndrome in 3 studies

Lysergic Acid Diethylamide: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
lysergic acid diethylamide : An ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
" There were no significant interactions between LSD treatment and Sert gene dosage in any of the behavioral domains measured."1.43Effects of LSD on grooming behavior in serotonin transporter heterozygous (Sert⁺/⁻) mice. ( Kalueff, AV; Kyzar, EJ; Stewart, AM, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kyzar, EJ1
Stewart, AM1
Kalueff, AV1
Halberstadt, AL1
Geyer, MA1
Heard, K1
Daly, FF1
O'Malley, G1
Rosen, N1

Reviews

1 review available for lysergic acid diethylamide and Serotonin Syndrome

ArticleYear
Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens.
    Neuropharmacology, 2011, Volume: 61, Issue:3

    Topics: Animals; Behavior; Behavior, Animal; Hallucinogens; Humans; Lysergic Acid Diethylamide; Nerve Tissue

2011

Other Studies

2 other studies available for lysergic acid diethylamide and Serotonin Syndrome

ArticleYear
Effects of LSD on grooming behavior in serotonin transporter heterozygous (Sert⁺/⁻) mice.
    Behavioural brain research, 2016, Jan-01, Volume: 296

    Topics: Animals; Disease Models, Animal; Grooming; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57B

2016
Respiratory distress after use of droperidol for agitation.
    Annals of emergency medicine, 1999, Volume: 34, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Drope

1999