lysergic acid diethylamide has been researched along with Migraine Disorders in 28 studies
Lysergic Acid Diethylamide: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
lysergic acid diethylamide : An ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Migraine is a primary headache disorder characterized by recurrent attacks." | 1.48 | Acute Migraine Headache: Treatment Strategies. ( Mayans, L; Walling, A, 2018) |
| "A 15-year-old girl suffered from common migraine." | 1.35 | [Recurrent cortical blindness after LSD-intake]. ( Bernhard, MK; Ulrich, K, 2009) |
| "Patients with classical migraine investigated between attacks had significantly fewer platelet 3H-imipramine binding sites than control subjects and this finding was more marked in males than in females." | 1.27 | Decreased platelet 3H-imipramine binding sites in classical migraine. ( Elliott, JM; Geaney, DP; Grahame-Smith, DG; Peet, KM; Rutterford, MG; Schächter, M, 1984) |
| "The vascular mechanism of migraine attacks--intracranial vasoconstriction during the prodromal stage and passive vasodilatation of extracranial arteries during the painful phase--has been confirmed by modern methods." | 1.26 | [Importance of chemical mediators for the pathogenesis and treatment of hemicrania]. ( Berde, B; Fanchamps, A, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (89.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayans, L | 1 |
| Walling, A | 1 |
| Bernhard, MK | 1 |
| Ulrich, K | 1 |
| Sewell, RA | 1 |
| Gottschalk, CH | 1 |
| FRIEDMAN, AP | 2 |
| LOSIN, S | 1 |
| DALESSIO, DJ | 6 |
| CAMP, WA | 2 |
| GOODELL, H | 3 |
| WOLFF, HG | 3 |
| DALSGAARD-NIELSEN, T | 1 |
| CHAPMAN, LF | 1 |
| ZILELI, T | 1 |
| CATTELL, M | 1 |
| EHRLICH, R | 1 |
| FORTUIN, F | 1 |
| HALE, AR | 1 |
| REED, AF | 1 |
| ELKIND, AH | 1 |
| DOMINGUEZ LAZARO, AR | 1 |
| SASTRE CASTILLO, A | 1 |
| PEREZ GUERRERO, J | 1 |
| CALLEJA CANELAS, JL | 1 |
| SICUTERI, F | 7 |
| CROWTHER, DL | 1 |
| ABRAMSON, HA | 2 |
| Geaney, DP | 1 |
| Rutterford, MG | 1 |
| Elliott, JM | 1 |
| Schächter, M | 1 |
| Peet, KM | 1 |
| Grahame-Smith, DG | 1 |
| Lake, F | 1 |
| Berde, B | 1 |
| Fanchamps, A | 1 |
| Anselmi, B | 1 |
| Del Bianco, PL | 1 |
| Rolo, A | 1 |
| Podvalová, I | 1 |
| Dlabac, A | 1 |
1 trial available for lysergic acid diethylamide and Migraine Disorders
| Article | Year |
|---|---|
Lysergic acid diethylamide (LSD-25). 38. Comparison with action of methysergide and psilocybin on test subjects.
Topics: Clinical Trials as Topic; Drug Tolerance; Humans; Lysergic Acid Diethylamide; Methysergide; Migraine | 1965 |
27 other studies available for lysergic acid diethylamide and Migraine Disorders
| Article | Year |
|---|---|
Acute Migraine Headache: Treatment Strategies.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Curriculum; Education, Medical, | 2018 |
[Recurrent cortical blindness after LSD-intake].
Topics: Adolescent; Blindness, Cortical; Electroencephalography; Evoked Potentials, Visual; Female; Hallucin | 2009 |
Problem child is no headache.
Topics: Cluster Headache; Hallucinogens; Humans; Lysergic Acid Diethylamide; Migraine Disorders; Treatment O | 2011 |
Evaluation of UML-491 in the treatment of vascular headaches. An analysis of the effects of 1-methyl-D-lysergic acid (plus) butanolamide bimaleate (methysergide).
Topics: Lysergic Acid; Lysergic Acid Diethylamide; Methysergide; Migraine Disorders; Vascular Headaches | 1961 |
Studies on headache. The mode of action of UML-491 and its relevance to the nature of vascular headache of the migraine type.
Topics: Headache; Humans; Lysergic Acid Diethylamide; Methysergide; Migraine Disorders; Vascular Headaches | 1961 |
[On the prophylactic treatment of migraine with deseril].
Topics: Lysergic Acid Diethylamide; Methysergide; Migraine Disorders | 1960 |
Studies in headache: further analysis of the mode of action of UML-491 and its relevance to the nature of vascular headache of the migraine type.
Topics: Headache; Lysergic Acid Diethylamide; Methysergide; Migraine Disorders; Vascular Headaches | 1961 |
Studies on headache. The responses of the bulbar conjunctival blood vessels during induced oliguria and diuresis, and their modification by UML-491.
Topics: Anuria; Conjunctiva; Diuresis; Headache; Lysergic Acid Diethylamide; Methysergide; Migraine Disorder | 1961 |
On migraine headache: serotonin and serotonin antagonism.
Topics: Antihypertensive Agents; Humans; Lysergic Acid Diethylamide; Migraine Disorders; Serotonin; Serotoni | 1962 |
Prophylaxis of frequent vascular headache with methysergide.
Topics: Headache; Lysergic Acid Diethylamide; Methysergide; Migraine Disorders; Vascular Headaches | 1962 |
Appraisal of methysergide in treatment of vascular headaches of migraine type.
Topics: Humans; Lysergic Acid Diethylamide; Methysergide; Migraine Disorders; Vascular Headaches | 1963 |
Recent experimental studies on headache.
Topics: Headache; Lysergic Acid Diethylamide; Migraine Disorders | 1963 |
[UML-491 (1-methyl-D-lysergic acid butanolamide) in the prevention and treatment of migraine and other types of headache].
Topics: Biomedical Research; Headache; Lysergic Acid; Lysergic Acid Diethylamide; Methysergide; Migraine Dis | 1962 |
PROPHYLACTIC TREATMENT OF MIGRAINE BY MEANS OF LYSERGIC ACID DERIVATIVES.
Topics: Biochemical Phenomena; Biochemistry; Electroencephalography; Ergot Alkaloids; Humans; Lysergic Acid; | 1963 |
MAST CELLS AND THEIR ACTIVE SUBSTANCES: THEIR ROLE IN THE PATHOGENESIS OF MIGRAINE.
Topics: Benzaldehydes; Biochemical Phenomena; Biochemistry; Bradykinin; Catecholamines; Dogs; Drug Tolerance | 1963 |
THE PROPHYLACTIC EFFECT OF 1-METHYL-D-LYSERGIC ACID BUTANOLAMIDE (METHYSERGIDE) IN THE TREATMENT OF VASCULAR HEADACHE. A CLINICAL STUDY.
Topics: Analgesics; Ergot Alkaloids; Facial Neuralgia; Humans; Lysergic Acid; Lysergic Acid Diethylamide; Me | 1964 |
ANTISEROTONIN ACTION OF LSD-25 AND OTHER LYSERGIC ACID DERIVATIVES: FACT AND FICTION.
Topics: Asthma; Autistic Disorder; Child; Hallucinogens; Humans; Hypersensitivity; Lysergic Acid; Lysergic A | 1964 |
CENTRAL MECHANISMS IN HEADACHE.
Topics: Brain; Brain Ischemia; Cerebral Infarction; Drug Therapy; Headache; Humans; Ischemic Attack, Transie | 1965 |
Identification of antiepileptic properties of a lysergic-acid-derivative-UML 491-serotonin antagonist; preliminary report.
Topics: Anticonvulsants; Epilepsy; Lysergic Acid; Lysergic Acid Diethylamide; Methysergide; Migraine Disorde | 1960 |
Prophylactic and therapeutic properties of 1-methyl-lysergic acid butanolamide in migraine.
Topics: Analgesics; Lysergic Acid; Lysergic Acid Diethylamide; Migraine Disorders; Serotonin | 1959 |
[First experiments in hemicrania and epilepsy with 1-methyl-lysergic acid butanolamide, a substance with antiserotonin effects].
Topics: Anencephaly; Epilepsy; Headache; Lysergic Acid; Lysergic Acid Diethylamide; Migraine Disorders | 1960 |
Decreased platelet 3H-imipramine binding sites in classical migraine.
Topics: Blood Platelets; Carrier Proteins; Female; Humans; Imipramine; Kinetics; Lysergic Acid Diethylamide; | 1984 |
Hypothesis: migraine, a central biochemical dysnociception.
Topics: Adult; Animals; Apomorphine; Circadian Rhythm; Dopamine; Female; Fever; Headache; Humans; Levodopa; | 1976 |
Treating psychosomatic disorders related to birth trauma.
Topics: Abreaction; Birth Injuries; Depression; Dermatitis, Atopic; Female; Humans; Labor, Obstetric; Lyserg | 1978 |
[Importance of chemical mediators for the pathogenesis and treatment of hemicrania].
Topics: 5-Hydroxytryptophan; Aminopyrine; Female; Histamine; Humans; Kinins; Lysergic Acid Diethylamide; Men | 1976 |
5-hydroxytryptamine supersensitivity as a new theory of headache and central pain: a clinical pharmacological approach with p-chlorophenylalanine.
Topics: Brain Chemistry; Drug Hypersensitivity; Fenclonine; Headache; Humans; Lysergic Acid Diethylamide; Me | 1973 |
Lysenyl, a new antiserotonin agent. Pharmacological and clinical survey.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Blood Pressure; Dose-Response Relationship, Drug | 1970 |