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lysergic acid diethylamide and Fetal Death

lysergic acid diethylamide has been researched along with Fetal Death in 9 studies

Lysergic Acid Diethylamide: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
lysergic acid diethylamide : An ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine.

Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.

Research Excerpts

ExcerptRelevanceReference
"One of five rats given a single subcutaneous injection of lysergic acid diethylamide (LSD) early in pregnancy appeared to abort early; two delivered stunted stillborn offspring at term, one delivered a littler of seven healthy and one underdeveloped young, and the last one delivered an apparently normal litter."3.64LSD: injection early in pregnancy produces abnormalities in offspring of rats. ( Alexander, GJ; Alexander, RB; Gold, GM; Miles, BE, 1967)
"Malformations of the brain, spinal cord, liver, and other viscera; body edema; and localized hemorrhages were found in fetal hamsters from mothers injected subcutaneously with a single dose of mescaline, lysergic acid diethylamide, or 2-bromo-D lysergic acid diethylamide on the 8th day of pregnancy."3.64Congenital malformations induced by mescaline, lysergic acid diethylamide, and bromolysergic acid in the hamster. ( Geber, WF, 1967)
"Lysergic acid diethylamide tartrate was given to 98 pregnant rats, 67 mice, and 22 hamsters as a single dose of 5 to 500 micrograms per kilogram of body weight per day either at the beginning of gestation or during the period of organogenesis."1.25LSD: no teratogenic action in rats, mice, and hamsters. ( Aubry, M; Dupuis, R; Roux, C, 1970)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexander, GJ2
Miles, BE2
Gold, GM2
Alexander, RB2
Robson, JM1
Cohen, MI1
Geber, WF1
Roux, C1
Dupuis, R1
Aubry, M1
DiPaolo, JA1
Givelber, HM1
Erwin, H1
Teraki, Y1

Reviews

1 review available for lysergic acid diethylamide and Fetal Death

ArticleYear
Testing drugs for teratogenicity and their effects on fertility. The present position.
    British medical bulletin, 1970, Volume: 26, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cannabis; Chlormadinone Acetate; Female; Fertility; Fetal Deat

1970

Other Studies

8 other studies available for lysergic acid diethylamide and Fetal Death

ArticleYear
LSD: injection early in pregnancy produces abnormalities in offspring of rats.
    Science (New York, N.Y.), 1967, Jul-28, Volume: 157, Issue:3787

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Female; Fetal Death; Lysergic Acid Diet

1967
The susceptibility of the fetus and child to chemical pollutants. Environmental exposures and biologic considerations of the adolescent in relation to chemical pollutants.
    Pediatrics, 1974, Volume: 53, Issue:5

    Topics: Adolescent; Alcoholism; Amenorrhea; Anabolic Agents; Bilirubin; Bone Development; Chromosomes; Diet

1974
Congenital malformations induced by mescaline, lysergic acid diethylamide, and bromolysergic acid in the hamster.
    Science (New York, N.Y.), 1967, Oct-13, Volume: 158, Issue:3798

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Cricetinae; Female; Fetal Death; Fetus; Graft vs Host D

1967
LSD: no teratogenic action in rats, mice, and hamsters.
    Science (New York, N.Y.), 1970, Aug-07, Volume: 169, Issue:3945

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cricetinae; Female; Fertility; Fetal Death;

1970
Lysergic acid diethylamide intake in pregnancy: fetal damage in rats.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 173, Issue:1

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Administration, Oral; Animals; Embryo, Mammalian

1970
Report of Inter-Society Commission for Heart Disease Resources. Prevention of Cardiovascular Disease. Primary prevention of congenital heart disease.
    Circulation, 1970, Volume: 41, Issue:6

    Topics: Child; Chromosome Aberrations; Female; Fetal Death; Heart Defects, Congenital; Humans; Infant; Infan

1970
Evaluation of teratogenicity of lysergic acid diethylamide.
    Nature, 1968, Nov-02, Volume: 220, Issue:5166

    Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Fetal Death; Fetus; Lysergic Acid Diethyla

1968
[Mechanism of lethal action of 5-HT on the fetus and the effect of its antagonists].
    Nihon Sanka Fujinka Gakkai zasshi, 1968, Volume: 20, Issue:12

    Topics: Animals; Female; Fetal Death; Fetus; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Methysergi

1968