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lysergic acid diethylamide and Aging

lysergic acid diethylamide has been researched along with Aging in 17 studies

Lysergic Acid Diethylamide: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
lysergic acid diethylamide : An ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Dose-response data were obtained from extracellular records of the firing of DRN neurons recorded in midbrain slices perfused with artificial cerebral spinal fluid containing varying concentrations of the drugs investigated."1.28Electrophysiological and biochemical characterization of the development of alpha 1-adrenergic and 5-HT1 receptors associated with dorsal raphe neurons. ( Gallager, DW; Smith, DA, 1989)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's5 (29.41)18.2507
2000's1 (5.88)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamazaki, M1
Okabe, M1
Yamamoto, N1
Yarimizu, J1
Harada, K1
WAPNER, S1
Niblock, MM1
Kinney, HC1
Luce, CJ1
Belliveau, RA1
Filiano, JJ1
Trulson, ME1
Howell, GA1
Waeber, C1
Palacios, JM1
Spigset, O2
Mjörndal, T2
Southall, MD1
Flinn, JM1
Holt, RW1
Chandhoke, V1
Fowler, CJ1
Sjöberg, E1
Tiger, G1
Sigurdh, J1
Allard, P1
Hägglöf, B1
Heikkila, JJ1
Brown, IR1
Jonsson, G1
Pollare, T1
Hallman, H1
Sachs, C1
Govoni, S1
Loddo, P1
Spano, PF1
Trabucchi, M1
Bourgoin, S1
Artaud, F1
Enjalbert, A1
Héry, F1
Glowinski, J1
Hamon, M1
Smith, DA1
Gallager, DW1
Schächter, M1
Geaney, DP1
Grahame-Smith, DG1
Cowen, PJ1
Elliott, JM1
Wikler, A1
Rosenberg, DE1
Hawthorne, JD1
Cassidy, TM1
Achkova, M1

Trials

1 trial available for lysergic acid diethylamide and Aging

ArticleYear
Age and effect of LSD-25 on pupil size and kneejerk threshold. Studies in chronic schizophrenic and nonpsychotic subjects.
    Psychopharmacologia, 1965, Jan-14, Volume: 7, Issue:1

    Topics: Adult; Aging; Clinical Trials as Topic; Humans; Injections, Intramuscular; Lysergic Acid Diethylamid

1965

Other Studies

16 other studies available for lysergic acid diethylamide and Aging

ArticleYear
Novel 5-HT5A receptor antagonists ameliorate scopolamine-induced working memory deficit in mice and reference memory impairment in aged rats.
    Journal of pharmacological sciences, 2015, Volume: 127, Issue:3

    Topics: Aging; Animals; Brain; Cognition Disorders; Dementia; Disease Models, Animal; Dose-Response Relation

2015
SOME ASPECTS OF A RESEARCH PROGRAM BASED ON AN ORGANISMIC-DEVELOPMENTAL APPROACH TO COGNITION: EXPERIMENTS AND THEORY.
    Journal of the American Academy of Child Psychiatry, 1964, Volume: 3

    Topics: Adolescent; Aging; Body Image; Child; Cognition; Geriatrics; Humans; Interpersonal Relations; Learni

1964
The development of the medullary serotonergic system in the piglet.
    Autonomic neuroscience : basic & clinical, 2004, Feb-27, Volume: 110, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Animals, Newborn; Binding, Competitive; Bloo

2004
Ontogeny of the behavioral effects of lysergic acid diethylamide in cats.
    Developmental psychobiology, 1984, Volume: 17, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Drug Tol

1984
Binding sites for 5-hydroxytryptamine-2 receptor agonists are predominantly located in striosomes in the human basal ganglia.
    Brain research. Molecular brain research, 1994, Volume: 24, Issue:1-4

    Topics: Adult; Aged; Aging; Animals; Basal Ganglia; Binding Sites; Binding, Competitive; Brain; Cats; Cattle

1994
Serotonin 5-HT2A receptor binding in platelets from healthy subjects as studied by [3H]-lysergic acid diethylamide ([3H]-LSD): intra- and interindividual variability.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Blood Platelets; Blood Pressure; Cell Membrane; Contraceptives, Oral

1997
Age dependent changes in serotonin and dopamine receptors in Aplysia californica.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 118, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Aplysia; Ganglia, Invertebrate; Lysergic Acid Diethylamide; Ra

1997
Serotonin stimulation of calcium mobilisation in human platelets: choice of units of measurement, effects of age and tobacco use, and correlation with serotonin2A receptor density.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 287, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amphetamines; Blood Platelets; Calcium; Female; H

1999
Binding of [(3)H]lysergic acid diethylamide to serotonin 5-HT(2A) receptors and of [(3)H]paroxetine to serotonin uptake sites in platelets from healthy children, adolescents and adults.
    Neuropsychobiology, 1999, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aging; Binding Sites; Blood Platelets; Child; Female; Humans; Lysergic Acid Dieth

1999
Disaggregation of brain polysomes after LSD in vivo. Involvement of LSD-induced hyperthermia.
    Neurochemical research, 1979, Volume: 4, Issue:6

    Topics: Aging; Animals; Apomorphine; Body Temperature; Brain; Chlorpromazine; Fever; Kidney; Lysergic Acid D

1979
Developmental plasticity of central serotonin neurons after 5,7-dihydroxytryptamine treatment.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Animals, Newborn; Central Nervous System; Dihydroxytryptami

1978
Dopamine receptor sensitivity in brain and retina of rats during aging.
    Brain research, 1977, Dec-23, Volume: 138, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Dose-Response Rela

1977
Acute changes in central serotonin metabolism induced by the blockade or stimulation of serotoninergic receptors during ontogenesis in the rat.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Brain; Female; Hydroxyindoleacetic Acid; In Vit

1977
Electrophysiological and biochemical characterization of the development of alpha 1-adrenergic and 5-HT1 receptors associated with dorsal raphe neurons.
    Brain research. Developmental brain research, 1989, Apr-01, Volume: 46, Issue:2

    Topics: Action Potentials; Aging; Animals; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Phenylephr

1989
Increased platelet membrane [3H]-LSD binding in patients on chronic neuroleptic treatment.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:4

    Topics: Adult; Aging; Antipsychotic Agents; Blood Platelets; Cell Membrane; Female; Humans; Kinetics; Lyserg

1985
[Age-related aspects of the psychic reactions of oligophrenics to the administration of lysergic acid diethylamide].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1965, Volume: 65, Issue:12

    Topics: Adolescent; Adult; Aging; Child; Humans; Intellectual Disability; Lysergic Acid Diethylamide; Middle

1965