lynestrenol and Endometriosis studies

Lynestrenol: A synthetic progestational hormone used often in mixtures with estrogens as an oral contraceptive (CONTRACEPTIVES, ORAL).

Endometriosis: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.

Research Excerpts

Excerpt	Relevance	Reference
"The Lipoprotein profile of 24 patients with endometriosis was determined before, during and after the treatment with the two steroid hormones Lynestrenol (10 mg/day) and Danazol (600-800 mg/day)."	7.67	[Lipoprotein changes during hormonal treatment of endometriosis with lynestrenol and danazol]. ( Cremer, P; Kuhn, W; Seidel, D; Teichmann, AT; Wieland, H, 1984)
"Luteinising hormone-releasing hormone agonist (Buserelin) therapy administered for a period of 6 months in 4 patients with longstanding, severe, danazol-resistant endometriosis, was found to be effective in reducing all complaints related to endometriosis."	7.67	Treatment with a luteinising hormone-releasing hormone analogue (Buserelin) in danazol-resistant endometriosis patients. ( Chadha, DR; Franssen, AM; Rolland, R; Vemer, HM; Willemsen, WN, 1986)
"The treatment of endometriosis with danazol or lynestrenol decreased cholesterol content of plasma high-density lipoproteins by 50% and 32%."	7.66	Effects of danazol and lynestrenol on serum lipoproteins in endometriosis. ( Hirvonen, E; Mälkönen, M; Manninen, V, 1980)
"Endometriosis is thought to be an ovarian-dependent benign disease that affects up to 12% of women during their reproductive life."	6.70	Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis. ( Förtig, P; Kienle, E; Lübben, G; Regidor, M; Regidor, PA; Ruwe, B; Schindler, AE; Schmidt, M, 2001)
"The Lipoprotein profile of 24 patients with endometriosis was determined before, during and after the treatment with the two steroid hormones Lynestrenol (10 mg/day) and Danazol (600-800 mg/day)."	3.67	[Lipoprotein changes during hormonal treatment of endometriosis with lynestrenol and danazol]. ( Cremer, P; Kuhn, W; Seidel, D; Teichmann, AT; Wieland, H, 1984)
"Three groups of patients with pelvic endometriosis were treated with medroxyprogesterone acetate (MPA) 50 mg/day (n = 10), lynestrenol (LYN) 10 mg/day (n = 25) and danazol (DAN) 600 mg/day (n = 25) respectively."	3.67	Lipid metabolic changes during hormonal treatment of endometriosis. ( Cremer, P; Kuhn, W; Seidel, D; Teichmann, AT; Wieland, H, 1988)
"Luteinising hormone-releasing hormone agonist (Buserelin) therapy administered for a period of 6 months in 4 patients with longstanding, severe, danazol-resistant endometriosis, was found to be effective in reducing all complaints related to endometriosis."	3.67	Treatment with a luteinising hormone-releasing hormone analogue (Buserelin) in danazol-resistant endometriosis patients. ( Chadha, DR; Franssen, AM; Rolland, R; Vemer, HM; Willemsen, WN, 1986)
"Fifty patients with moderate or severe endometriosis received 5 mg/day lynestrenol for 6 months prior to microsurgery."	3.67	Combined (hormonal and microsurgical) therapy in infertile women with endometriosis. ( Casanas-Roux, F; Donnez, J; Karaman, Y; Lemaire-Rubbers, M; Nisolle-Pochet, M, 1987)
"The treatment of endometriosis with danazol or lynestrenol decreased cholesterol content of plasma high-density lipoproteins by 50% and 32%."	3.66	Effects of danazol and lynestrenol on serum lipoproteins in endometriosis. ( Hirvonen, E; Mälkönen, M; Manninen, V, 1980)
"Marked transformation and involution phenomena were observed in relation to lynestrenol-induced pseudogravidal changes of mucus membrane in a small (nut-size) retrocervical endometriosis."	3.65	[The changing morphological picture of endometriosis. 1. Unusual regression in a pseudopregnant retrocervical endometriosis caused by ovulation inhibitors]. ( Schmid, KO, 1973)
"Endometriosis is thought to be an ovarian-dependent benign disease that affects up to 12% of women during their reproductive life."	2.70	Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis. ( Förtig, P; Kienle, E; Lübben, G; Regidor, M; Regidor, PA; Ruwe, B; Schindler, AE; Schmidt, M, 2001)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (91.67)	18.7374
1990's	3 (6.25)	18.2507
2000's	1 (2.08)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
GREGOIRE, L	1
FONTAINE, J	1
NICOLAS, A	1
SOIVA, K	1
CASTREN, O	1
CAPRIOLI, N	1
VIZZONE, A	1
SUBRIZI, D	1
FERIN, J	1
NEVINNY-STICKEL, J	1
KAISER, R	1
ARNOLD, M	1
TSCHERNE, E	1
HAUSER, GA	1
BORGLIN, NE	2
THEANDER, G	1
WEHLIN, L	1
Kowalski, ML	1
Szmidt, M	1
Rozniecki, J	1
Teichmann, AT	2
Wieland, H	2
Cremer, P	2
Kuhn, W	2
Seidel, D	2
Mälkönen, M	1
Manninen, V	1
Hirvonen, E	1
Wenzl, R	1
Schurz, B	1
Freude, G	1
Huber, J	1
Donnez, J	4
Nisolle, M	2
Casanas-Roux, F	3
Brion, P	1
Da Costa Ferreira, N	1
Regidor, PA	1
Regidor, M	1
Schmidt, M	1
Ruwe, B	1
Lübben, G	1
Förtig, P	1
Kienle, E	1
Schindler, AE	1
Clerckx, F	1
Casanas, F	1
Franssen, AM	1
Rolland, R	1
Chadha, DR	1
Willemsen, WN	1
Vemer, HM	1
Nisolle-Pochet, M	2
Lemaire-Rubbers, M	1
Karaman, Y	1
Hansen, CL	1
Clementsen, P	1
Høegholm, A	1
Tóth, F	1
Horn, B	1
Primász, P	1
Czyba, JC	1
Zada, FS	1
Cottinet, D	1
Pellet, H	1
Schmid, KO	1
Richter, K	4
Laudańska, E	1
Davies, R	1
Kalinowski, S	1
Müller, A	1
Dubach, UC	1
Demol, R	1
Vandekerckhove, D	1
Hooghe, R	1
Schubert, L	1
Giarola, P	1
Gibelli, A	1
Iurlaro, F	1
Minucci, D	1
Sciarretta, A	1
Gromadzki, W	1
Wiskont-Buczkowska, H	1
Giedroyć, B	1
Korte, W	2
Beck, KJ	2
Scherholz, KP	1
Fiehn, G	1
Fiehn, E	1
Willmes, HG	1
Timonen, S	1
Johansson, CJ	1
Kourides, IA	1
Kistner, RW	1
Husslein, H	1
Mach, S	1
Dapunt, O	1
Plate, WP	1
Gaudefroy, M	1

Article	Year
[GnRH analogs versus gestagens in therapy of endometriosis]. Gynakologisch-geburtshilfliche Rundschau, 1993, Volume: 33, Issue:4 Topics: Adult; Delayed-Action Preparations; Endometriosis; Female; Humans; Injections, Intramuscular; Lynest	1993
Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2001, Volume: 15, Issue:3 Topics: Adult; Delayed-Action Preparations; Dysmenorrhea; Dyspareunia; Endometriosis; Estradiol; Female; Fer	2001
Evaluation of preoperative use of danazol, gestrinone, lynestrenol, buserelin spray and buserelin implant, in the treatment of endometriosis associated infertility. Progress in clinical and biological research, 1990, Volume: 323 Topics: Adult; Buserelin; Clinical Trials as Topic; Danazol; Endometriosis; Female; Gestrinone; Humans; Infe	1990
[Clinical results of administration of gestagens (Anovlar 21 and Lyndiol 2,5) in endometriosis]. Ginekologia polska, 1968, Volume: 39, Issue:9 Topics: Clinical Trials as Topic; Contraceptives, Oral; Endometriosis; Female; Humans; Lynestrenol; Mestrano	1968

Article	Year
[Treatment of endometriosis by lynestrenol]. Bulletin de la Societe royale belge de gynecologie et d'obstetrique, 1963, Volume: 33 Topics: Endometriosis; Female; Humans; Lynestrenol	1963
THE CONSERVATIVE TREATMENT OF ENDOMETRIOSIS WITH LYNESTRENOL. Annales chirurgiae et gynaecologiae Fenniae, 1963, Volume: 52 Topics: Colposcopy; Endometriosis; Ethinyl Estradiol; Female; Humans; Lynestrenol; Pregnancy	1963
[THE ASSOCIATION OF LINESTRENOL AND MESTRANOL IN GYNECOLOGICAL HORMONE THERAPY]. La Clinica terapeutica, 1964, Mar-31, Volume: 28 Topics: Amenorrhea; Contraceptive Agents; Contraceptives, Oral; Dysmenorrhea; Endometriosis; Female; Gynecol	1964
[THERAPEUTIC INDICATIONS FOR OVARIAN BLOCK BY THE ADMINISTRATION OF PROGESTATIONAL HORMONES]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1964, Oct-02, Volume: 40 Topics: Amenorrhea; Anemia; Anemia, Hypochromic; Breast Diseases; Endometriosis; Female; Humans; Infertility	1964
[PRACTICAL EXPERIENCES WITH OVULATION INHIBITION]. Bibliotheca gynaecologica, 1965, Volume: 32 Topics: Chlormadinone Acetate; Drug Therapy; Dysmenorrhea; Endometriosis; Ethinyl Estradiol; Female; Humans;	1965
[PRACTICAL EXPERIENCES WITH OVULATION INHIBITION]. Bibliotheca gynaecologica, 1965, Volume: 32 Topics: Amenorrhea; Chlormadinone Acetate; Drug Therapy; Dysmenorrhea; Endometriosis; Ethinyl Estradiol; Fem	1965
[PRACTICAL EXPERIENCES WITH OVULATION INHIBITION]. Bibliotheca gynaecologica, 1965, Volume: 32 Topics: Drug Therapy; Dysmenorrhea; Endometriosis; Female; Humans; Infertility; Infertility, Female; Lynestr	1965
[PRACTICAL EXPERIENCES WITH OVULATION INHIBITION]. Bibliotheca gynaecologica, 1965, Volume: 32 Topics: Contraceptive Agents; Contraceptives, Oral; Drug Therapy; Dysmenorrhea; Endometriosis; Ethinyl Estra	1965
[PRACTICAL EXPERIENCES WITH OVULATION INHIBITORS]. Bibliotheca gynaecologica, 1965, Volume: 32 Topics: Amenorrhea; Drug Therapy; Dysmenorrhea; Endometriosis; Ethinyl Estradiol; Female; Humans; Infertilit	1965
ORAL CONTRACEPTIVES AND LIVER DAMAGE. British medical journal, 1965, May-15, Volume: 1, Issue:5445 Topics: Chemical and Drug Induced Liver Injury; Contraceptives, Oral; Drug Synergism; Drug Therapy; Endometr	1965
ROENTGENOGRAPHIC OBSERVATIONS ON THE EFFECT OF PSEUDOPREGNANCY IN ENDOMETRIOSIS. The Journal of obstetrics and gynaecology of the British Commonwealth, 1965, Volume: 72 Topics: Drug Therapy; Endometriosis; Female; Humans; Lynestrenol; Pseudopregnancy; Radiography; Uterine Neop	1965
Catamenial pneumothorax. European journal of respiratory diseases, 1980, Volume: 61, Issue:3 Topics: Chlormadinone Acetate; Contraceptives, Oral, Combined; Drug Combinations; Endometriosis; Female; Hum	1980
[Lipoprotein changes during hormonal treatment of endometriosis with lynestrenol and danazol]. Geburtshilfe und Frauenheilkunde, 1984, Volume: 44, Issue:3 Topics: Adult; Arteriosclerosis; Coronary Disease; Danazol; Endometriosis; Female; Humans; Lipoproteins; Lyn	1984
Effects of danazol and lynestrenol on serum lipoproteins in endometriosis. Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:5 Topics: Adult; Danazol; Endometriosis; Female; Humans; Lipoproteins; Lynestrenol; Pregnadienes	1980
Stereometric evaluation of peritoneal endometriosis and endometriotic nodules of the rectovaginal septum. Human reproduction (Oxford, England), 1996, Volume: 11, Issue:1 Topics: Biopsy; Endometriosis; Endometrium; Epithelium; Female; Gonadotropin-Releasing Hormone; Humans; Lyne	1996
Lipid metabolic changes during hormonal treatment of endometriosis. Maturitas, 1988, Volume: 10, Issue:1 Topics: Adult; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Chol	1988
Treatment with a luteinising hormone-releasing hormone analogue (Buserelin) in danazol-resistant endometriosis patients. European journal of obstetrics, gynecology, and reproductive biology, 1986, Volume: 23, Issue:5-6 Topics: Adult; Buserelin; Danazol; Drug Resistance; Endometriosis; Estradiol; Female; Follicle Stimulating H	1986
Histologic study of ovarian endometriosis after hormonal therapy. Fertility and sterility, 1988, Volume: 49, Issue:3 Topics: Adult; Buserelin; Endometriosis; Female; Gestrinone; Humans; Lynestrenol	1988
Combined (hormonal and microsurgical) therapy in infertile women with endometriosis. Fertility and sterility, 1987, Volume: 48, Issue:2 Topics: Adult; Body Weight; Combined Modality Therapy; Dyspareunia; Endometriosis; Female; Humans; Infertili	1987
[Catamenial pneumothorax]. Ugeskrift for laeger, 1986, Aug-18, Volume: 148, Issue:34 Topics: Adult; Endometriosis; Female; Humans; Lynestrenol; Menstruation; Pleural Neoplasms; Pneumothorax; Ra	1986
[Clinical importance and pharmacodynamics of synthetic progesteroids]. Zeitschrift fur arztliche Fortbildung, 1970, Feb-01, Volume: 64, Issue:3 Topics: Acne Vulgaris; Adult; Animals; Chiari-Frommel Syndrome; Endometriosis; Endometrium; Ethisterone; Fem	1970
[Course of endometrium autograft in rats and golden hamsters subjected to diverse endocrine conditionings]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1971, Volume: 165, Issue:1 Topics: Animals; Cricetinae; Diethylstilbestrol; Disease Models, Animal; Endometriosis; Endometrium; Estradi	1971
[The changing morphological picture of endometriosis. 1. Unusual regression in a pseudopregnant retrocervical endometriosis caused by ovulation inhibitors]. Zentralblatt fur Gynakologie, 1973, Jun-01, Volume: 95, Issue:22 Topics: Adult; Endometriosis; Female; Humans; Lynestrenol; Pelvic Neoplasms; Pseudopregnancy; Remission, Spo	1973
[Investigations on 324 patients with histologically proved external endometriosis followed up for as long as 17 years. 3. Therapy (author's transl)]. Geburtshilfe und Frauenheilkunde, 1974, Volume: 34, Issue:7 Topics: Adult; Endometriosis; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Hysterectomy; La	1974
[Extragenital endometriosis. Report of a case of pulmonary endometriosis]. Schweizerische medizinische Wochenschrift, 1971, Aug-28, Volume: 101, Issue:34 Topics: Abortion, Spontaneous; Drug Combinations; Endometriosis; Female; Hemoptysis; Hormones; Humans; Lung	1971
Immunological determination of urinary LH after surgical intervention with or without castration. Acta endocrinologica. Supplementum, 1969, Volume: 141 Topics: Castration; Endometriosis; Estrogens; Female; Humans; Hysterectomy; Luteinizing Hormone; Lynestrenol	1969
[Estroprogestinic associations in the preclimacteric syndrome: blood coagulation problems]. Giornale di gerontologia, 1969, Volume: 17, Issue:11 Topics: Adult; Blood Coagulation Disorders; Endometriosis; Female; Humans; Lynestrenol; Menopause; Menstruat	1969
[Lynestrenol in gynecologic pathology]. Rivista italiana di ginecologia, 1969, Volume: 53, Issue:12 Topics: Adult; Endometriosis; Endometrium; Female; Humans; Lynestrenol; Menstruation Disturbances	1969
[The treatment of endometriosis with gestagens as a procedure against tubal sterility]. Ginekologia polska, 1970, Volume: 41, Issue:5 Topics: Endometriosis; Female; Humans; Infertility, Female; Lynestrenol; Pregnancy	1970
[Surgical treatment of endometriosis and long-term therapy with lynestrenol]. Geburtshilfe und Frauenheilkunde, 1970, Volume: 30, Issue:2 Topics: Adult; Endometriosis; Female; Humans; Lynestrenol; Middle Aged; Time Factors	1970
[Endometriosis treated with Lynestrenol]. Ugeskrift for laeger, 1967, Apr-27, Volume: 129, Issue:17 Topics: Adolescent; Adult; Endometriosis; Female; Humans; Lynestrenol; Middle Aged	1967
[Tolerance of the gestagen-estrogen combination Noracyclin in contraception and gynecologic indications]. Medizinische Klinik, 1967, Jun-16, Volume: 62, Issue:24 Topics: Adult; Body Weight; Contraception; Drug Synergism; Drug Tolerance; Endometriosis; Ethinyl Estradiol;	1967
[Conservative anagement of endometriosis externa]. Munchener medizinische Wochenschrift (1950), 1968, May-10, Volume: 110, Issue:19 Topics: Endometriosis; Female; Follow-Up Studies; Humans; Lynestrenol; Neoplasm Recurrence, Local	1968
)Significance of lynestrenol (Orgametril)-induced amenorrhea in the therapy of endometriosis externa. Wiener klinische Wochenschrift, 1968, May-31, Volume: 80, Issue:22 Topics: Adult; Amenorrhea; Endometriosis; Female; Humans; Lynestrenol; Neoplasm Recurrence, Local	1968
Endometriosis treated with lynestrenol. Annales chirurgiae et gynaecologiae Fenniae, 1968, Volume: 57, Issue:2 Topics: Adult; Cervix Mucus; Endometriosis; Female; Humans; Lynestrenol; Pregnancy; Uterine Hemorrhage; Vagi	1968
Three new synthetic progestins in the treatment of endometriosis. Obstetrics and gynecology, 1968, Volume: 31, Issue:6 Topics: Endometriosis; Estradiol; Estrogens; Female; Humans; Lynestrenol; Mestranol; Norethindrone; Pregnanc	1968
[Drug therapy of endometriosis]. Archiv fur Gynakologie, 1969, Volume: 207, Issue:1 Topics: Androgens; Endometriosis; Estrogens; Female; Humans; Lynestrenol; Progestins	1969
[Surgical and long-term lynestrenol treatment of endometriosis]. Archiv fur Gynakologie, 1969, Volume: 207, Issue:1 Topics: Endometriosis; Female; Humans; Lynestrenol	1969
[Significance of vaginal surgery in the treatment of external endometriosis]. Zentralblatt fur Gynakologie, 1965, Dec-18, Volume: 87, Issue:51 Topics: Adolescent; Endometriosis; Female; Humans; Hysterectomy; Laparotomy; Lynestrenol	1965
[Bladder endometriosis and its treatment at the Universitäts-Frauenklinik Berlin (1941-1963)]. Zeitschrift fur Urologie und Nephrologie, 1965, Volume: 58, Issue:8 Topics: Adult; Endometriosis; Female; Humans; Lynestrenol; Mestranol; Middle Aged; Progesterone; Radium; Tes	1965
[Histologic and hormone-analytical studies in acyclic continuous therapy with ovulation-inhibitors]. Geburtshilfe und Frauenheilkunde, 1966, Volume: 26, Issue:5 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Anemia; Biopsy; Endometriosis; Estrogens; Female; Gonado	1966
Effect of progestational compounds on ovarian endometriosis. Nederlandsch tijdschrift voor verloskunde en gynaecologie, 1966, Volume: 66, Issue:4 Topics: Adult; Endometriosis; Female; Humans; Lynestrenol; Mestranol; Ovarian Diseases	1966
[Clinical study of a synthetic progestagen at low doses]. Gynecologie pratique, 1966, Volume: 17 Topics: Adolescent; Adult; Endometriosis; Female; Genital Diseases, Female; Humans; Lynestrenol; Menstruatio	1966

lynestrenol and Endometriosis

Research Excerpts

Research

Studies (48)

Authors

Reviews

Trials

Other Studies