ly 293558 and Ache
ly 293558 has been researched along with Ache in 5 studies
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Alt, A; Arnold, BM; Bell, MG; Bleakman, D; Bleisch, TJ; Buckmaster, JL; Castano, AM; Del Prado, M; Dominguez, E; Escribano, A; Filla, SA; Ho, KH; Hudziak, KJ; Iyengar, S; Jones, CK; Martinez-Perez, JA; Mateo, A; Mathes, BM; Mattiuz, EL; Ogden, AM; Ornstein, PL; Shannon, HE; Simmons, RM; Stack, DR; Stratford, RE; Winter, MA; Wu, Z | 1 |
| Alt, A; Arnold, BM; Bell, MG; Bleakman, D; Bleisch, TJ; Castaño, AM; Clawson, DK; Del Prado, M; Dominguez, E; Escribano, AM; Filla, SA; Ho, KH; Hudziak, KJ; Iyengar, S; Jones, CK; Martinez-Perez, JA; Mateo, A; Mathes, BM; Mattiuz, EL; Ogden, AM; Ornstein, PL; Shannon, HE; Simmons, RM; Stack, DR; Stratford, RE; Winter, MA; Wu, Z | 1 |
| Lam, V; Schettler, J; Wallace, MS | 1 |
| Caruso, R; Chappell, AS; Gracely, RH; Hostetter, MP; Lee, G; Max, MB; Sang, CN; Schoepp, DD; Whitcup, S | 1 |
| Gilron, I | 1 |
Reviews
1 review(s) available for ly 293558 and Ache
| Article | Year |
|---|---|
LY-293558. Eli Lilly & Co.
Topics: Animals; Cerebrovascular Disorders; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Contraindications; Excitatory Amino Acid Antagonists; Humans; Isoquinolines; Pain; Receptors, AMPA; Structure-Activity Relationship; Tetrazoles | 2001 |
Trials
2 trial(s) available for ly 293558 and Ache
| Article | Year |
|---|---|
NGX426, an oral AMPA-kainate antagonist, is effective in human capsaicin-induced pain and hyperalgesia.
Topics: Adult; Capsaicin; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Isoquinolines; Male; Pain; Pain Measurement; Prodrugs; Receptors, AMPA; Receptors, Kainic Acid; Sensory System Agents; Tetrazoles; Young Adult | 2012 |
AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans.
Topics: Adult; Analgesics, Non-Narcotic; Capsaicin; Dose-Response Relationship, Drug; Hot Temperature; Humans; Hyperalgesia; Isoquinolines; Male; Middle Aged; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Receptors, AMPA; Receptors, Kainic Acid; Skin; Tetrazoles | 1998 |
Other Studies
2 other study(ies) available for ly 293558 and Ache
| Article | Year |
|---|---|
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Biological Availability; Cell Line; Disease Models, Animal; Humans; Hyperalgesia; Pain; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Spinal Cord | 2005 |
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy.
Topics: Administration, Oral; Amino Acid Sequence; Animals; Disease Models, Animal; Isoquinolines; Male; Molecular Sequence Data; Pain; Prodrugs; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Structure-Activity Relationship; Tetrazoles | 2013 |