ly-2157299 and Diabetes-Mellitus

ly-2157299 has been researched along with Diabetes-Mellitus* in 1 studies

Other Studies

1 other study(ies) available for ly-2157299 and Diabetes-Mellitus

ArticleYear
Discovery of a drug candidate for GLIS3-associated diabetes.
    Nature communications, 2018, 07-11, Volume: 9, Issue:1

    GLIS3 mutations are associated with type 1, type 2, and neonatal diabetes, reflecting a key function for this gene in pancreatic β-cell biology. Previous attempts to recapitulate disease-relevant phenotypes in GLIS3

    Topics: Animals; Cell Differentiation; Cell Line; Diabetes Mellitus; DNA-Binding Proteins; Drug Discovery; Gene Expression Profiling; Human Embryonic Stem Cells; Humans; Hypoglycemic Agents; Insulin Secretion; Insulin-Secreting Cells; Male; Mice, SCID; Mutation; Pyrazoles; Quinolines; Repressor Proteins; Trans-Activators; Transcription Factors; Transplantation, Heterologous

2018