ly 171883 has been researched along with Experimental Hepatoma in 3 studies
LY 171883: structure in first source; leukotriene receptor antagonist
tomelukast : A member of the class of acetophenones that is 1-phenylethanone substituted at position 2 by a hydroxy group, a propyl group at position 3 and a 4-(1H-tetrazol-5-yl)butoxy group at position 4. A leukotriene antagonist, it exhibits anti-asthmatic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Survival was not adversely affected by treatment, however, body weight of males and females in the high dose group was significantly lower than that of controls." | 1.28 | Effects of chronic treatment with the leukotriene D4-antagonist compound LY171883 on B6C3F1 mice. ( Bendele, AM; Eacho, PI; Foxworthy, PS; Hoover, DM; van Lier, RB, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helvering, LM | 1 |
| Richardson, FC | 1 |
| Horn, DM | 1 |
| Rexroat, MA | 1 |
| Engelhardt, JA | 1 |
| Richardson, KK | 1 |
| Eacho, PI | 2 |
| Lanier, TL | 1 |
| Brodhecker, CA | 1 |
| Bendele, AM | 1 |
| Hoover, DM | 1 |
| van Lier, RB | 1 |
| Foxworthy, PS | 1 |
3 other studies available for ly 171883 and Experimental Hepatoma
| Article | Year |
|---|---|
H-ras 61st codon activation in archival proliferative hepatic lesions isolated from female B6C3F1 mice exposed to the leukotriene D4-antagonist, LY171883.
Topics: Acetophenones; Animals; Base Sequence; Carcinogens; Codon; DNA Primers; Female; Genes, ras; Leukotri | 1994 |
Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: comparison of WY-14,643 to clofibric acid, nafenopin and LY171883.
Topics: Acetophenones; Animals; Bromodeoxyuridine; Clofibric Acid; DNA Replication; Immunohistochemistry; Li | 1991 |
Effects of chronic treatment with the leukotriene D4-antagonist compound LY171883 on B6C3F1 mice.
Topics: Acetophenones; Animals; Autacoids; Body Weight; Carcinogens; Chemical and Drug Induced Liver Injury; | 1990 |