ly 171883 has been researched along with Enlarged Liver in 1 studies
LY 171883: structure in first source; leukotriene receptor antagonist
tomelukast : A member of the class of acetophenones that is 1-phenylethanone substituted at position 2 by a hydroxy group, a propyl group at position 3 and a 4-(1H-tetrazol-5-yl)butoxy group at position 4. A leukotriene antagonist, it exhibits anti-asthmatic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The doses required to elicit hepatomegaly greatly exceeded doses that produce pharmacological efficacy in animals and those that are expected to be used clinically." | 1.27 | Characterization of liver enlargement induced by compound LY171883 in rats. ( Eacho, PI; Foxworthy, PS; Johnson, WD; van Lier, RB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eacho, PI | 1 |
| Foxworthy, PS | 1 |
| Johnson, WD | 1 |
| van Lier, RB | 1 |
1 other study available for ly 171883 and Enlarged Liver
| Article | Year |
|---|---|
Characterization of liver enlargement induced by compound LY171883 in rats.
Topics: Acetophenones; Animals; Azoles; Cricetinae; DNA; Dose-Response Relationship, Drug; Hepatomegaly; Liv | 1985 |