ly 171883 has been researched along with Anaphylactic Reaction in 3 studies
LY 171883: structure in first source; leukotriene receptor antagonist
tomelukast : A member of the class of acetophenones that is 1-phenylethanone substituted at position 2 by a hydroxy group, a propyl group at position 3 and a 4-(1H-tetrazol-5-yl)butoxy group at position 4. A leukotriene antagonist, it exhibits anti-asthmatic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since the non-steroidal anti-inflammatory agents, indomethacin and aspirin, were inactive, cyclooxygenase products are not involved in the anaphylactic reaction in boosted or unboosted mice." | 3.69 | Involvement of leukotrienes in allergic inflammation in mice. ( Cordeiro, RS; Vargaftig, BB; Zuany-Amorim, C, 1994) |
| " The edematogenic reaction appeared 5 min after the intraplantar injection of ovalbumin, peaked at 30 min after the antigenic challenge, and decreased thereafter." | 3.68 | Effect of PAF-acether antagonists on active anaphylactic mouse paw edema. ( Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB, 1991) |
| " In an attempt to study this problem, two 5-lipoxygenase inhibitors, the novel compound RG 6866, N-methyl-4-benzyloxyphenyl acetohydroxamic acid, and AA 861 have been examined in Langendorff-perfused guinea pig hearts undergoing cardiac anaphylaxis and compared to indomethacin and LY 171883, a cyclooxygenase inhibitor and a leukotriene antagonist, respectively." | 3.67 | Effects of 5-lipoxygenase inhibition on cardiac anaphylaxis in isolated guinea pig hearts. ( Jolly, SR; Travis, J; Van Inwegen, RG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zuany-Amorim, C | 1 |
| Cordeiro, RS | 2 |
| Vargaftig, BB | 2 |
| Amorim, CZ | 1 |
| Henriques, MG | 1 |
| Weg, VB | 1 |
| Jolly, SR | 1 |
| Travis, J | 1 |
| Van Inwegen, RG | 1 |
3 other studies available for ly 171883 and Anaphylactic Reaction
| Article | Year |
|---|---|
Involvement of leukotrienes in allergic inflammation in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A | 1994 |
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A | 1991 |
Effects of 5-lipoxygenase inhibition on cardiac anaphylaxis in isolated guinea pig hearts.
Topics: Acetophenones; Anaphylaxis; Animals; Arachidonate Lipoxygenases; Benzoquinones; Benzyl Compounds; Bl | 1989 |