Page last updated: 2024-09-03

luzindole and Disease Models, Animal

luzindole has been researched along with Disease Models, Animal in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's12 (66.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Huang, J; Li, L; Luo, Y; Shen, Y; Tang, L; Yang, Y; Zhang, L1
Ding, C; Huang, B; Li, H; Meng, Q; Qian, C; Zou, Q1
Jiang, J; Jin, X; Lu, F; Ma, X; Xia, X; Yang, S; Zheng, C; Zhu, W1
Azizi, M; Kashani, IR; Mokhtari, T; Nadji, SA; Omidi, N; Pasbakhsh, P; Pourabdollah, M; Sadr, M; Zendehdel, A1
Fink, T; Glas, M; Kiefer, D; Kleber, A; Mathes, AM; Rensing, H; Reus, E; Volk, T; Wolf, A; Wolf, B; Wolff, M1
Chen, CR; Chen, L; Cheng, NN; Huang, ZL; Laudon, M; Liu, YY; Qu, WM; Urade, Y; Yin, D1
Chen, H; Jang, L; Li, Z; Rui, BB; Wei, W; Xu, WP; Yang, JM1
Chen, Y; Dai, ZS; He, LJ; Huang, L; Ke, QF; Wu, JZ; Wu, WH1
Heymann, P; Kubulus, D; Mathes, AM; Rensing, H; Waibel, L; Weiler, J; Wolf, B1
Mickle, A; Miranda, A; Sengupta, JN; Shahmohammadi, G; Sood, M; Zhang, Z1
Dehpour, AR; Hojati, A; Moezi, L; Shafaroodi, H1
Albrecht, E; Bähr, I; Mühlbauer, E; Peschke, E1
Bedini, A; Comai, S; Fraschini, F; Gobbi, G; Mor, M; Ochoa-Sanchez, R; Rainer, Q; Rivara, S; Spadoni, G; Tarzia, G1
Bahadir, GM; Berna, T; Berrak, Y; Can, E; Handan, K; Ipek, E; Umit, UM1
Leung, LS; Stewart, LS1
Li, F; Liu, RY; Qian, ZX; Zhou, L1
Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J1

Other Studies

18 other study(ies) available for luzindole and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Luzindole attenuates LPS/d-galactosamine-induced acute hepatitis in mice.
    Innate immunity, 2020, Volume: 26, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apoptosis; Disease Models, Animal; Galactosamine; Hepatitis; Humans; Interleukin-6; Lipopolysaccharides; Liver; Melatonin; Mice; Mice, Inbred BALB C; Receptors, Melatonin; Tryptamines; Tumor Necrosis Factor-alpha

2020
Fetal liver mesenchymal stem cells restore ovarian function in premature ovarian insufficiency by targeting MT1.
    Stem cell research & therapy, 2019, 11-29, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Female; Fetus; Granulosa Cells; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Oxidative Stress; Primary Ovarian Insufficiency; Receptor, Melatonin, MT1; RNA Interference; RNA, Small Interfering; Tryptamines; Up-Regulation

2019
The value of applying a melatonin antagonist (Luzindole) in improving the success rate of the bipedal rat scoliosis model.
    BMC musculoskeletal disorders, 2017, 04-04, Volume: 18, Issue:1

    Topics: Animals; Disease Models, Animal; Melatonin; Random Allocation; Rats, Sprague-Dawley; Scoliosis; Tryptamines

2017
Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 68

    Topics: Animals; Animals, Newborn; Antioxidants; Carcinogens; Catalase; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation, Developmental; Glutathione Peroxidase; Intermediate Filaments; Malformations of Cortical Development; Malondialdehyde; Maze Learning; Melatonin; Methylazoxymethanol Acetate; Mice; Mice, Inbred BALB C; Nitroprusside; Pregnancy; Prenatal Exposure Delayed Effects; Superoxide Dismutase; Tryptamines

2018
Melatonin receptors mediate improvements of survival in a model of polymicrobial sepsis.
    Critical care medicine, 2014, Volume: 42, Issue:1

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Indenes; Interleukin-10; Interleukin-6; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Knockout; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Sepsis; Tryptamines; Tumor Necrosis Factor-alpha

2014
Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.
    Psychopharmacology, 2014, Volume: 231, Issue:20

    Topics: Analgesics; Animals; Disease Models, Animal; Hyperalgesia; Hypnotics and Sedatives; Indoles; Male; Melatonin; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Piperazines; Pyrans; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Melatonin; Receptors, Opioid; Sciatic Nerve; Serotonin Antagonists; Sleep Wake Disorders; Tryptamines

2014
Melatonin Upregulates the Activity of AMPK and Attenuates Lipid Accumulation in Alcohol-induced Rats.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2016, Volume: 51, Issue:1

    Topics: Alanine Transaminase; AMP-Activated Protein Kinases; Animals; Antioxidants; Aspartate Aminotransferases; Disease Models, Animal; Fatty Liver, Alcoholic; Hep G2 Cells; Humans; Lipid Metabolism; Lipid Peroxidation; Liver; Malondialdehyde; Melatonin; Rats; Receptor, Melatonin, MT1; Superoxide Dismutase; Triglycerides; Tryptamines; Up-Regulation

2016
Effect of Melatonin and Calmodulin in an Idiopathic Scoliosis Model.
    BioMed research international, 2016, Volume: 2016

    Topics: Animals; Calmodulin; Disease Models, Animal; Female; Humans; Lighting; Melatonin; Rats; Scoliosis; Tamoxifen; Tryptamines

2016
Selective activation of melatonin receptors with ramelteon improves liver function and hepatic perfusion after hemorrhagic shock in rat.
    Critical care medicine, 2008, Volume: 36, Issue:10

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Indenes; Infusions, Intravenous; Liver Circulation; Liver Diseases; Liver Function Tests; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Sensitivity and Specificity; Shock, Hemorrhagic; Tryptamines

2008
Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: a centrally mediated process.
    Pain, 2010, Volume: 149, Issue:3

    Topics: Analgesics; Animals; Colitis; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Melatonin; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Tryptamines; Visceral Afferents

2010
The interaction of melatonin and agmatine on pentylenetetrazole-induced seizure threshold in mice.
    Epilepsy & behavior : E&B, 2011, Volume: 22, Issue:2

    Topics: Agmatine; Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Melatonin; Mice; Pentylenetetrazole; Prazosin; Receptors, Melatonin; Seizures; Time Factors; Tryptamines

2011
Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.
    Journal of pineal research, 2012, Volume: 53, Issue:4

    Topics: Animals; Cell Line; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; GTP-Binding Protein alpha Subunits, Gq-G11; Liver; Male; Melanins; Mice; Mice, Knockout; Pertussis Toxin; Phosphatidylinositol 3-Kinase; Rats; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Glucagon; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Tissue Culture Techniques; Tryptamines; Type C Phospholipases

2012
Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Dec-03, Volume: 39, Issue:2

    Topics: Acetamides; Aniline Compounds; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Partial Agonism; Feeding Behavior; Male; Maze Learning; Melatonin; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT2; Tetrahydronaphthalenes; Tryptamines

2012
Role of melatonin and luzindole in rat mammary cancer.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:6

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Disease Models, Animal; DNA Fragmentation; Estradiol; Female; Heme Oxygenase-1; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Oxidative Stress; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley; Tryptamines

2012
Hippocampal melatonin receptors modulate seizure threshold.
    Epilepsia, 2005, Volume: 46, Issue:4

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Exploratory Behavior; Functional Laterality; GABA Antagonists; Hippocampus; Locomotion; Male; Muscimol; Pilocarpine; Rats; Rats, Wistar; Receptors, Melatonin; Seizures; Tetrahydronaphthalenes; Tryptamines

2005
[The effect of melatonin on the regulation of collagen accumulation and matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 mRNA and protein in a murine model of chronic asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2007, Volume: 30, Issue:7

    Topics: Animals; Asthma; Collagen; Dexamethasone; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Inbred BALB C; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tryptamines

2007
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
    Annals of neurology, 2002, Volume: 51, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease Models, Animal; Excitatory Amino Acid Agonists; Free Radical Scavengers; Humans; Hypothermia, Induced; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Melatonin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuroprotective Agents; Neurotoxins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetrahydronaphthalenes; Tryptamines

2002