lutetium-lu-177-dotatate and Hyperaldosteronism

lutetium-lu-177-dotatate has been researched along with Hyperaldosteronism* in 1 studies

Other Studies

1 other study(ies) available for lutetium-lu-177-dotatate and Hyperaldosteronism

ArticleYear
Resolution of Hyperreninemia, Secondary Hyperaldosteronism, and Hypokalemia With 177Lu-DOTATATE Induction and Maintenance Peptide Receptor Radionuclide Therapy in a Patient With Pancreatic Neuroendocrine Tumor.
    Clinical nuclear medicine, 2015, Volume: 40, Issue:11

    A 54-year-old woman presented with a history of nausea, vomiting, diarrhea, and recurrent episodes of severe hypokalemia requiring hospitalization. Imaging revealed a pancreatic mass with liver metastases, histologically confirmed to be a neuroendocrine tumor. Elevated active renin and aldosterone levels were identified, and the patient was treated with 4 induction cycles of Lu-DOTATATE, which resolved the diarrhea, nausea, and hypokalemia, and normalized the renin and aldosterone levels. After 3 additional maintenance Lu-DOTATATE treatments, the pancreatic tumor had decreased in size, was deemed operable, and was resected. She remains on maintenance Lu-DOTATATE therapy with progression-free survival of 45 months thus far.

    Topics: Female; Humans; Hyperaldosteronism; Hypokalemia; Liver Neoplasms; Middle Aged; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals

2015