lutetium-lu-177-dotatate and Carotid-Body-Tumor

Paragangliomas are rare benign neuroendocrine tumors, and 80% of all paragangliomas are either carotid body tumors or glomus jugulare tumors. We present a case of recurrent unresectable carotid body paraganglioma with nodal and T7 vertebral metastases in a 30-year-old man 6 years postsurgery detected with Ga DOTANOC PET/CT and was administered with peptide receptor radionuclide therapy using Lu DOTATATE. After 5 cycles of Lu DOTATATE (total cumulative activity of 750 mCi [27 GBq]), significant response at the primary site on Ga DOTANOC PET/CT and complete disappearance of nodal and T7 vertebral metastases were noted.

Topics: Adult; Carotid Body Tumor; Humans; Male; Neoplasm Recurrence, Local; Octreotide; Organometallic Compounds; Paraganglioma; Radionuclide Imaging; Spinal Neoplasms