Compounds > lutetium
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lutetium and Colonic Neoplasms

lutetium has been researched along with Colonic Neoplasms in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.00)18.2507
2000's12 (48.00)29.6817
2010's9 (36.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fathi, M; Ghannadi-Maragheh, M; Taghikhani, M; Yavari, K1
Elgström, E; Eriksson, SE; Nilsson, R; Ohlsson, T; Örbom, A; Strand, SE; Tennvall, J1
Elgström, E; Eriksson, SE; Ljungberg, O; Nilsson, R; Ohlsson, TG; Orbom, A; Strand, SE; Tennvall, J1
Bäck, T; Elgström, E; Eriksson, SE; Jensen, H; Lindegren, S; Nilsson, R; Ohlsson, T; Tennvall, J1
Baidoo, KE; Brechbiel, MW; Milenic, DE; Yong, KJ1
Aarts, F; Bleichrodt, RP; Boerman, OC; de Man, B; Hendriks, T; Lomme, R1
Aarts, F; Bleichrodt, RP; Boerman, OC; de Jong, GM; Hendriks, T; Heskamp, S1
Agazzi, A; Aricò, D; Bodei, L; De Cicco, C; De Simone, M; Pacifici, M; Paganelli, G; Quarna, J; Sansovini, M; Sierra, ML1
Boerman, OC; Eek, A; Franssen, G; Goldenberg, DM; McBride, WJ; Oyen, WJ; Rossi, EA; Schoffelen, R; Sharkey, RM; van der Graaf, WT1
Chung, JK; Jeong, JM; Jeong, SY; Ju, CH; Kim, YJ; Lee, BC; Lee, DS; Lee, MC; Lee, YS1
Eriksson, SE; Nilsson, R; Ohlsson, T; Tennvall, J2
Eberwein, DJ; Ingram, AC; Knick, VC; Murray, DM; Ryan, CH; Stimmel, JB; Thurmond, LM; Witherspoon, SM1
Buchsbaum, DJ; Roberson, PL; Rogers, BE; Yokoyama, S1
Beitzel, MP; Brechbiel, MW; Chappell, LL; Garmestani, K; Ma, D; Milenic, DE; Venditto, V1
Axworthy, DB; Cutler, CS; Embree, MF; Jia, F; Jurisson, SS; Ketring, AR; Lewis, MR; Owen, NK; Schultz, J; Theodore, LJ; Zhang, J1
Axworthy, DB; Buchsbaum, DJ; Carpenter, M; Chaudhuri, TR; Khazaeli, MB; LoBuglio, AF; Schultz, J; Zinn, KR1
Forte, LR; Giblin, MF; Hoffman, TJ; Shelton, TD; Sieckman, GL; Volkert, WA1
Almqvist, Y; Divgi, CR; Steffen, AC; Sundin, A; Tolmachev, V1
Aarts, F; Bleichrodt, RP; Boerman, OC; Hendriks, T; Koppe, MJ; Oyen, WJ1
Cheng, R; Colcher, D; Eggensperger, D; Fordyce, W; Goeckeler, W; Kruper, WJ; Milenic, DE; Schlom, J; Schott, ME; Siler, K1
Carrasquillo, JA; Chung, Y; Curt, G; Feuerstein, I; Milenic, DE; Mulligan, T; Paik, C; Perentesis, P; Reynolds, J; Schlom, J1
Brechbiel, MW; Chappell, LL; Dadachova, E; Garmestani, K; Ma, D; Milenic, DE; Schlom, J; Yordanov, A1
Cheng, RC; Fordyce, WA; Milenic, DE; Schlom, J; Schott, ME; Whitlow, M; Wood, JF; Yokota, T1
Cheng, R; Colcher, D; Eggensperger, D; Goeckeler, W; Houchens, D; Kaplan, D; Milenic, DE; Miller, LS; Schlom, J; Siler, K1

Trials

1 trial(s) available for lutetium and Colonic Neoplasms

ArticleYear
Phase I study of intravenous Lu-labeled CC49 murine monoclonal antibody in patients with advanced adenocarcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:12

    Topics: Adenocarcinoma; Adult; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Lutetium; Male; Middle Aged; Neoplasms; Radioimmunotherapy; Radioisotopes; Radiotherapy Dosage

1995

Other Studies

24 other study(ies) available for lutetium and Colonic Neoplasms

ArticleYear
Demonstration of dose dependent cytotoxic activity in SW480 colon cancer cells by ¹⁷⁷Lu-labeled siRNA targeting IGF-1R.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:4

    Topics: Base Sequence; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Radiation; Humans; Isotope Labeling; Lutetium; Radiation Tolerance; Radiochemistry; Radioisotopes; Receptor, IGF Type 1; RNA, Messenger; RNA, Small Interfering

2013
The intratumoral distribution of radiolabeled 177Lu-BR96 monoclonal antibodies changes in relation to tumor histology over time in a syngeneic rat colon carcinoma model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Immunoconjugates; Isotope Labeling; Lewis Blood Group Antigens; Lutetium; Male; Neovascularization, Pathologic; Radiation Dosage; Radioisotopes; Rats; Time Factors

2013
Change in cell death markers during (177)Lu-mAb radioimmunotherapy-induced rejection of syngeneic rat colon carcinoma.
    Cancer biotherapy & radiopharmaceuticals, 2014, Volume: 29, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Colonic Neoplasms; Humans; Immunotoxins; Lutetium; Male; Radioimmunotherapy; Radioisotopes; Rats

2014
Sequential radioimmunotherapy with 177Lu- and 211At-labeled monoclonal antibody BR96 in a syngeneic rat colon carcinoma model.
    Cancer biotherapy & radiopharmaceuticals, 2014, Volume: 29, Issue:6

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Astatine; Colonic Neoplasms; Disease Models, Animal; Humans; Lutetium; Radioimmunotherapy; Radioisotopes; Radiopharmaceuticals; Rats

2014
Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from (177)Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor Xenografts.
    International journal of molecular sciences, 2016, May-16, Volume: 17, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chromosome Aberrations; Colonic Neoplasms; DNA Breaks, Double-Stranded; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoconjugates; Injections, Intraperitoneal; Linear Energy Transfer; Lutetium; Mice, Nude; Neoplasm Transplantation; Rad51 Recombinase; Radioimmunotherapy; Radioisotopes; Reverse Transcriptase Polymerase Chain Reaction; Trastuzumab; Xenograft Model Antitumor Assays

2016
The effects of adjuvant experimental radioimmunotherapy and hyperthermic intraperitoneal chemotherapy on intestinal and abdominal healing after cytoreductive surgery for peritoneal carcinomatosis in the rat.
    Annals of surgical oncology, 2008, Volume: 15, Issue:11

    Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Combined Modality Therapy; Disease Models, Animal; Gelatinases; Hydroxyproline; Hyperthermia, Induced; Injections, Intraperitoneal; Intestines; Lutetium; Male; Mitomycin; Peritoneal Neoplasms; Radioimmunotherapy; Rats; Rats, Inbred Strains; Survival Rate; Treatment Outcome; Wound Healing

2008
Radioimmunotherapy prevents local recurrence of colonic cancer in an experimental model.
    The British journal of surgery, 2009, Volume: 96, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Body Weight; Cell Line, Tumor; Colonic Neoplasms; Lutetium; Male; Neoplasm Recurrence, Local; Neoplasm Transplantation; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Rats; Tumor Burden

2009
Lymphocytic toxicity in patients after peptide-receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE and 90Y-DOTATOC.
    Cancer biotherapy & radiopharmaceuticals, 2009, Volume: 24, Issue:6

    Topics: Adult; Aged; B-Lymphocytes; Colonic Neoplasms; Duodenal Neoplasms; Female; Humans; Ileal Neoplasms; Lung Neoplasms; Lutetium; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Octreotide; Organometallic Compounds; Pancreatic Neoplasms; Yttrium Radioisotopes

2009
Pretargeted 177Lu radioimmunotherapy of carcinoembryonic antigen-expressing human colonic tumors in mice.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Line, Tumor; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Haptens; Humans; Lutetium; Male; Mice; Mice, Inbred BALB C; Peptides; Radioimmunotherapy; Radioisotopes

2010
Development of a ¹⁷⁷Lu-labeled RGD derivative for targeting angiogenesis.
    Cancer biotherapy & radiopharmaceuticals, 2010, Volume: 25, Issue:6

    Topics: Animal Structures; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Delivery Systems; Drug Stability; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Kidney; Lutetium; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Neovascularization, Pathologic; Oligopeptides; Radioisotopes; Radiopharmaceuticals; Tissue Distribution

2010
Repeated radioimmunotherapy with 177Lu-DOTA-BR96 in a syngeneic rat colon carcinoma model.
    Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Blood Platelets; Body Weight; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Radiation; Immunoconjugates; Leukocytes; Lutetium; Male; Radioimmunotherapy; Radioisotopes; Rats; Rats, Inbred BN

2012
Treatment with unlabeled mAb BR96 after radioimmunotherapy with 177Lu-DOTA-BR96 in a syngeneic rat colon carcinoma model.
    Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Colonic Neoplasms; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Heterocyclic Compounds, 1-Ring; Immunoenzyme Techniques; Lutetium; Male; Radioimmunotherapy; Radioisotopes; Rats; Rats, Inbred BN

2012
Adenocarcinoma cells exposed in vitro to Navelbine or Taxol increase Ep-CAM expression through a novel mechanism.
    Cancer immunology, immunotherapy : CII, 2003, Volume: 52, Issue:7

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Cell Adhesion Molecules; Cell Survival; Chromium; Colonic Neoplasms; Epithelial Cell Adhesion Molecule; Female; G2 Phase; Humans; In Vitro Techniques; Lutetium; Male; Mice; Mice, Nude; Mitosis; Paclitaxel; Prostatic Neoplasms; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2003
Three-dimensional dose model for the comparison of 177Lu-HuCC49DeltaCH2 and 177Lu-HuCC49 radioimunotherapy in mice bearing intraperitoneal xenografts.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:2

    Topics: Aniline Compounds; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Dose-Response Relationship, Radiation; Heterocyclic Compounds; Humans; Lutetium; Mice; Mice, Nude; Models, Biological; Neoplasms, Experimental; Peritoneal Neoplasms; Radioimmunotherapy; Radiotherapy Dosage; Tissue Distribution; Transplantation, Heterologous

2003
Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins.
    Nuclear medicine and biology, 2003, Volume: 30, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Chelating Agents; Colonic Neoplasms; Female; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Lutetium; Metabolic Clearance Rate; Mice; Organ Specificity; Radioimmunoassay; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

2003
Biological comparison of 149Pm-, 166Ho-, and 177Lu-DOTA-biotin pretargeted by CC49 scFv-streptavidin fusion protein in xenograft-bearing nude mice.
    Nuclear medicine and biology, 2004, Volume: 31, Issue:2

    Topics: Animals; Antibodies, Neoplasm; Biotin; Cell Line, Tumor; Colonic Neoplasms; Drug Delivery Systems; Holmium; Humans; Immunoglobulin Fragments; Injections, Intravenous; Lutetium; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Organometallic Compounds; Promethium; Radioimmunotherapy; Radioisotopes; Radiopharmaceuticals; Recombinant Fusion Proteins; Streptavidin; Tissue Distribution

2004
Intraperitoneal pretarget radioimmunotherapy with CC49 fusion protein.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Nov-15, Volume: 11, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Biotin; Cell Line, Tumor; Colonic Neoplasms; Glycoproteins; Humans; Indium Radioisotopes; Injections, Intraperitoneal; Iodine Radioisotopes; Lutetium; Mice; Mice, Nude; Organometallic Compounds; Radioimmunotherapy; Radioisotopes; Streptavidin; Survival Analysis; Time Factors; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays; Yttrium Radioisotopes

2005
In vitro and in vivo evaluation of 177Lu- and 90Y-labeled E. coli heat-stable enterotoxin for specific targeting of uroguanylin receptors on human colon cancers.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:4

    Topics: Animals; Bacterial Toxins; Cell Line, Tumor; Colonic Neoplasms; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Stability; Escherichia coli; Female; Hot Temperature; Humans; Isotope Labeling; Lutetium; Metabolic Clearance Rate; Mice; Mice, Inbred ICR; Natriuretic Peptides; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Cell Surface; Tissue Distribution; Yttrium Radioisotopes

2006
In vitro and in vivo characterization of 177Lu-huA33: a radioimmunoconjugate against colorectal cancer.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Colonic Neoplasms; Drug Stability; Female; Humans; Immunoconjugates; Lutetium; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Radioimmunotherapy; Radioisotopes; Tissue Distribution

2006
A comparison between radioimmunotherapy and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal carcinomatosis of colonic origin in rats.
    Annals of surgical oncology, 2007, Volume: 14, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Body Weight; Colonic Neoplasms; Combined Modality Therapy; Disease Models, Animal; Hyperthermia, Induced; Infusions, Parenteral; Lutetium; Mitomycin; Neoplasms, Experimental; Peritoneal Neoplasms; Radioimmunotherapy; Rats; Rats, Inbred Strains; Survival Rate; Treatment Outcome

2007
Biodistribution and preclinical radioimmunotherapy studies using radiolanthanide-labeled immunoconjugates.
    Cancer, 1994, Feb-01, Volume: 73, Issue:3 Suppl

    Topics: Aniline Compounds; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Colonic Neoplasms; Glycoproteins; Heterocyclic Compounds; Humans; Immunotoxins; Iodine Radioisotopes; Lutetium; Metals, Rare Earth; Mice; Mice, Nude; Neoplasm Transplantation; Radioimmunotherapy; Radioisotopes; Samarium; Tissue Distribution; Transplantation, Heterologous; Yttrium Radioisotopes

1994
In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications.
    Nuclear medicine and biology, 2002, Volume: 29, Issue:4

    Topics: Adenocarcinoma; Aniline Compounds; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Female; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Isothiocyanates; Lutetium; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution; Whole-Body Counting; Xenograft Model Antitumor Assays

2002
Differential metabolic patterns of iodinated versus radiometal chelated anticarcinoma single-chain Fv molecules.
    Cancer research, 1992, Nov-15, Volume: 52, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Iodine Radioisotopes; Lutetium; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Radioisotopes; Recombinant Proteins; Tissue Distribution

1992
Monoclonal antibody-based therapy of a human tumor xenograft with a 177lutetium-labeled immunoconjugate.
    Cancer research, 1991, Jun-01, Volume: 51, Issue:11

    Topics: Adenocarcinoma, Mucinous; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Humans; Immunoglobulin G; Lutetium; Mice; Mice, Nude; Radioisotopes; Radiotherapy Dosage; Tissue Distribution; Tumor Cells, Cultured

1991