lutetium has been researched along with Cancer of Prostate in 99 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 15 (15.15) | 29.6817 |
2010's | 52 (52.53) | 24.3611 |
2020's | 32 (32.32) | 2.80 |
Authors | Studies |
---|---|
Boros, E; Cingoranelli, SJ; Lapi, SE; Loveless, CS; Schlyer, D; Vaughn, BA | 1 |
Mumtaz, M; Shahid, A; Sheikh, N; Younis, MN | 1 |
Burkett, BJ | 1 |
Balieiro, LM; Benedetto, R; Bortoleti de Araújo, E; Brandão Freire, MR; de Jesus Silva, J; de Queiroz Souza Passos, P; Ferreira Dos Santos, CS; Marumo, MH; Pereira Dias, LA; Teixeira, LFS; Vieira, DP; Vivaldini, BF; Wieczorek Villas Boas, CA | 1 |
Hindié, E | 1 |
Kashihara, K; Kashihara, T | 1 |
Berruti, A; Dalla Volta, A; Grisanti, S | 1 |
Kraus, BJ; Morris, MJ; Sartor, O | 1 |
Alexoff, D; Choi, SR; Kung, HF; Li, L; Ploessl, K; Yao, X; Zha, Z; Zhao, R; Zhu, L | 1 |
Almaguel, F; Armstrong, E; Chin, BB; Flavell, RR; Gayed, IW; Ippisch, RC; Morley, A; Pantel, AR; Parent, EE; Savir-Baruch, B | 1 |
Boughdad, S; Digklia, A; Dolcan, A; Dromain, C; Homicsko, K; Peters, S; Prior, J; Schaefer, N; Trimech, M | 1 |
Karnes, RJ; Kemble, J; Kwon, ED | 1 |
de Bakker, M; Dominicus, N; Janssen, M; Konijnenberg, MW; Meeuwis, A; Nagarajah, J; Peters, SMB | 1 |
Crowley, JR | 1 |
Baum, R; Bodei, L; Bozkurt, MF; Czernin, J; Delgado Bolton, RC; Eiber, M; Ezziddin, S; Fanti, S; Fendler, WP; Forrer, F; Haberkorn, U; Herrmann, K; Hicks, RJ; Hope, TA; Kabasakal, L; Konijnenberg, M; Kopka, K; Kratochwil, C; Lassmann, M; Mottaghy, FM; Oyen, W; Rahbar, K; Schöder, H; Virgolini, I; Wester, HJ | 1 |
Azad, A; Hofman, MS; Iravani, A; Violet, J | 1 |
Flechsig, P; Giesel, FL; Haberkorn, U; Hohenfellner, M; Holland-Letz, T; Kopka, K; Kratochwil, C; Mavriopoulou, E; Mier, W; Rathke, H; Röhrich, M | 1 |
Taneja, SS | 1 |
Akbarian, R; Fattahi, K; Ghodsirad, MA; Javanmard, B; Kaghazchi, F; Pirayesh, E; Tavakoli, M | 1 |
Allen, JC; Kanesvaran, R; Lam, WWC; Ler, ASL; Ng, DCE; Somanesan, S; Tay, YS; Thang, SP; Tong, AKT; Wong, ASC | 1 |
Bögemann, M; Herrmann, K; Radtke, JP; Rahbar, K | 1 |
Dahlbom, M; Reiter, RE; Tsai, WK; Wu, AM; Zettlitz, KA | 1 |
Pirayesh, E | 1 |
Ahmadzadehfar, H; Alamdar, R; Attenberger, U; Conrad, R; Essler, M; Marinova, M; Mücke, M | 1 |
Bolzati, C; Duatti, A | 1 |
Dalm, SU; de Blois, E; de Jong, M; de Ridder, C; Haeck, J; Konijnenberg, MW; Nonnekens, J; Ruigrok, EAM; Stuurman, D; van Gent, DC; van Vliet, N; van Weerden, WM | 1 |
Grobbee, DE; Hehakaya, C; Lam, MGEH; Moors, EHM; Verburg, FA; Verkooijen, HM | 1 |
Tagawa, ST | 1 |
Civan, C; Ekenel, M; Has Simsek, D; Kuyumcu, S; Sanli, Y | 1 |
Das, N; Goyal, S; Madan, R; Mittal, BR; Satapathy, S; Singh, SK; Sood, A | 1 |
de Bakker, M; de Lange, F; Eek, A; Gotthardt, M; Jentzen, W; Konijnenberg, MW; Mehra, N; Muselaers, CHJ; Nagarajah, J; Peters, SMB; Privé, BM; Witjes, JA | 1 |
Alghazo, O; Buteau, J; Cumberbatch, M; Eapen, R; Koschel, S; Lawrentschuk, N; Loh, R; Murphy, DG | 1 |
Ahmadzadehfar, H; Becker, A; Eppard, E; Essler, M; Feldmann, G; Fisang, C; Kürpig, S; Yordanova, A | 1 |
Anderson, CJ; Berkman, CE; Beyer, SK; Choy, CJ; Geruntho, JJ; Langton-Webster, B; Latoche, JD; Ling, X | 1 |
Eiber, M; Fendler, WP; Herrmann, K; Kratochwil, C; Rahbar, K | 1 |
Acar, O; Demirkol, MO; Esen, T; Falay, O; Kiremit, MC; Ucar, B | 1 |
Ferdinandus, J; Hofman, MS; Sandhu, S; Violet, J | 1 |
Kumar, R; Mittal, BR; Parihar, AS; Singh, SK; Vadi, SK | 1 |
Turner, JH | 1 |
Assam, I; Jüptner, M; Lützen, U; Zuhayra, M | 1 |
Chakraborty, S; Chakravarty, R; Dash, A; Sarma, HD; Vimalnath, KV | 1 |
Baum, RP; Kulkarni, HR; Langbein, T; Lehmann, C; Mueller, D; Schuchardt, C; Singh, A; Zhang, J | 1 |
Chen, X; Jacobson, O; Kiesewetter, DO; Lang, L; Ma, Y; Niu, G; Szajek, LP; Tian, R; Wang, Z | 1 |
Ferretti, A; Gross, MD; Rubello, D; Viglianti, BL; Wale, DJ; Wong, KK | 1 |
Cooperberg, M; Eapen, RS; Hofman, MS; Lawrentschuk, N; Murphy, DG; Nzenza, TC | 1 |
D'Alessandria, C; Eiber, M; Gafita, A; Heck, M; Knorr, K; Rauscher, I; Retz, M; Tauber, R; Weber, WA; Wester, HJ | 1 |
Ahmadzadehfar, H; Essler, M; Feldmann, G; Gaertner, FC; Hauser, S; Kürpig, S; Linden, P; Meisenheimer, M; Yordanova, A | 1 |
Aranda-Lara, L; Azorín-Vega, E; Ferro-Flores, G; Jiménez-Mancilla, N; Nava-Cabrera, MA; Rojas-Calderón, E | 1 |
Escudero-Castellanos, A; Ferro-Flores, G; Isaac-Olivé, K; Luna-Gutiérrez, M; Morales-Ávila, E; Ocampo-García, B; Santos-Cuevas, C | 1 |
Eberlein, U; Lapa, C; Lassmann, M; Muhtadi, R; Scherthan, H; Schumann, S; Serfling, S | 1 |
Acar, E; Aksu, A; Bekiş, R; Çapa Kaya, G; Derebek, E; Özdoğan, Ö | 1 |
Burger, IA; Deberle, LM; Eberli, D; Hermanns, T; Kranzbühler, B; Müller, C; Salemi, S; Sulser, T; Umbricht, CA | 1 |
Antonarakis, ES; Denmeade, SR; Eisenberger, MA; Eshleman, JR; Isaacsson Velho, P; Luo, J; Paller, CJ; Piana, D; Pomper, MG; Riel, S; Rowe, SP | 1 |
Batra, SK; Fan, W; Garrison, JC; Lele, SM; Rachagani, S; Zhang, W; Zhou, Z | 1 |
Borkowski, S; Braun, F; Dumont, RA; Maecke, H; Mansi, R; Reubi, JC; Tamma, M; Weber, WA | 1 |
Bao, A; Cheng, Z; Cutler, CS; Jiang, L; Liu, H; Miao, Z; Ren, G; Shi, H | 1 |
Huxol, E; Mindt, TL; Valverde, IE | 1 |
Brandt-Larsen, M; Juhl, K; Kjaer, A; Madsen, J; Persson, M; Ploug, M; Rasmussen, P | 1 |
Breeman, WA; de Blois, E; de Jong, M; Krenning, EP; Maina, T; Marsouvanidis, PJ; Melis, M; Nock, BA | 1 |
Cho, EH; Choi, SM; Kim, JJ; Lee, Sy; Lim, JC; Nam, SS; Park, SH; Park, UJ | 2 |
Afshar-Oromieh, A; Bauder-Wüst, U; Benešová, M; Eder, M; Haberkorn, U; Kopka, K; Kratochwil, C; Mier, W; Schäfer, M | 1 |
Baum, RP; Beykan, S; Eiber, M; Klette, I; Kulkarni, HR; Lassmann, M; Schottelius, M; Schwaiger, M; Simecek, J; Weineisen, M; Wester, HJ; Yildiz, A | 1 |
Akyurek, S; Kucuk, NO; Ozkan, E; Soydal, C | 1 |
Knapp, FF; Pillai, AM | 1 |
Elgqvist, J; Larsson, E; Strand, SE; Timmermand, OV | 1 |
Dietlein, M; Drzezga, A; Eschner, W; Fischer, T; Hohberg, M; Kobe, C; Schmidt, M; Wild, M | 1 |
Ahmadzadehfar, H; Bode, A; Claesener, M; Eppard, E; Heinzel, A; Rahbar, K; Schmidt, M; Yordanova, A | 1 |
Abuqbeitah, M; Çavdar, İ; Demir, M; Gündüz, H; Kabasakal, L; Uslu-Beşli, L; Vatankulu, B; Yeyin, N; Yıldırım, Ö | 1 |
Banerjee, S; Das, T; Guleria, M; Kale, C; Lele, VR; Parab, A; Sarma, HD; Shah, H | 1 |
Chakraborty, S; Chakravarty, R; Dash, A; Sen, IB; Shetty, P; Vimalnath, KV | 1 |
Banerjee, S; Das, T; Guleria, M | 1 |
Baum, RP; Beer, AJ; Glatting, G; Kletting, P; Kulkarni, HR; Schuchardt, C; Shahinfar, M; Singh, A | 1 |
Ahmadzadehfar, H; Essler, M; Rahbar, K; Schäfers, M | 1 |
Ahmadzadehfar, H; Bartenstein, P; Baum, RP; Bögemann, M; Brenner, W; Drzezga, A; Essler, M; Eveslage, M; Fendler, WP; Haberkorn, U; Heinzel, A; Heuschkel, M; Kratochwil, C; Krause, BJ; Kulkarni, HR; Luster, M; Lützen, U; Marx, M; Meyer, PT; Mottaghy, FM; Pfestroff, A; Prasad, V; Rahbar, K; Ruf, J; Schäfers, M; Schmidt, M | 1 |
Eiber, M; Herrmann, K | 1 |
Eiber, M; Heck, MM; Knorr, K; Kratochwil, C; Retz, M; Tauber, R | 1 |
Blanksby, A; Emmett, L; Lee, J; Shin, J; Violet, J; Willowson, K | 1 |
Brechbiel, MW; Davis, ID; Kelly, MP; Lee, FT; Lee, ST; Scott, AM; Smyth, FE | 1 |
Tweedle, MF | 1 |
Bander, NH; Beltran, H; Goldsmith, SJ; Matulich, D; Nanus, DM; Osborne, J; Parmar, S; Petrillo, K; Tagawa, ST; Vallabhajosula, S | 1 |
Chang, CH; Chang, TJ; Chen, LC; Chiu, SP; Chuang, CH; Fu, YK; Ho, CL; Lee, TW; Lee, WC; Liu, IH; Wu, YH | 1 |
Boisclair, J; Bruchertseifer, F; Frischknecht, M; Maecke, HR; Morgenstern, A; Provencher-Bolliger, A; Reubi, JC; Wild, D; Zhang, H | 1 |
Couto, RM; De Araújo, EB; Grallert, SR; Melero, LT; Mengatti, J; Pujatti, PB; Santos, JS; Soares, CR; Suzuki, MF | 1 |
Goldsmith, SJ; Joyce, MA; Kostakoglu, L; Liu, H; Milowsky, M; Nanus, DM; Trabulsi, EJ; Vallabhajosula, S; Yao, D | 1 |
Eberwein, DJ; Ingram, AC; Knick, VC; Murray, DM; Ryan, CH; Stimmel, JB; Thurmond, LM; Witherspoon, SM | 1 |
Bander, NH; Goldsmith, SJ; Kostakoglu, L; Milowsky, MI; Nanus, DM; Vallabahajosula, S | 1 |
Chen, J; Hinni, K; Maecke, HR; Reubi, JC; Waldherr, C; Waser, B; Zhang, H | 1 |
Bander, NH; Goldsmith, SJ; Hamacher, KA; Konishi, S; Kostakoglu, L; Kothari, PA; Kuji, I; Milowski, MI; Nanus, DM; Vallabhajosula, S | 1 |
Bander, NH; Goldsmith, SJ; Kostakoglu, L; Milowsky, MI; Nanus, DM; Vallabhajosula, S | 2 |
Scott, AM | 1 |
Bander, NH; Goldsmith, SJ; Hamacher, KA; Konishi, S; Kostakoglu, L; Milowski, MI; Nanus, DM; Vallabhajosula, S | 1 |
Hoffman, TJ; Johnson, CV; Ma, L; Perry, MC; Shelton, T; Smith, CJ; Volkert, WA | 1 |
Arunachalam, T; Bogdan, NJ; Cappelletti, E; Chen, J; Eaton, SM; Feng, W; Fox, JS; Lantry, LE; Lattuada, L; Linder, KE; Maddalena, ME; Metcalfe, EC; Nunn, AD; Raju, N; Reubi, JC; Swenson, RE; Thomas, R; Tweedle, MF | 1 |
Eisenhut, M; Maecke, HR; Reubi, JC; Schuhmacher, J; Waser, B; Wild, D; Zhang, H | 1 |
Cutler, CS; Hoffman, T; Hu, F; Jurisson, SS; Sieckman, G; Volkert, WA | 1 |
15 review(s) available for lutetium and Cancer of Prostate
Article | Year |
---|---|
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals | 2022 |
Addressing the need for more therapeutic options in neuroendocrine prostate cancer.
Topics: Carcinoma, Neuroendocrine; Humans; Intracellular Signaling Peptides and Proteins; Lutetium; Male; Membrane Proteins; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radioisotopes | 2023 |
Lutetium-177 prostate-specific membrane antigen (PSMA) theranostics: practical nuances and intricacies.
Topics: Combined Modality Therapy; Dipeptides; Disease Management; Drug Administration Schedule; Follow-Up Studies; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Molecular Imaging; Molecular Targeted Therapy; Neoplasm Staging; Patient Selection; Positron Emission Tomography Computed Tomography; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Retreatment; Theranostic Nanomedicine; Treatment Outcome | 2020 |
[PSMA radioligand therapy in patients with advanced prostate cancer].
Topics: Dipeptides; Germany; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiopharmaceuticals; Treatment Outcome | 2020 |
The emerging value of 64Cu for molecular imaging and therapy.
Topics: Antigens, Surface; Chelating Agents; Coordination Complexes; Copper Radioisotopes; Gallium Radioisotopes; Glutamate Carboxypeptidase II; Humans; Iodine Radioisotopes; Lutetium; Male; Molecular Imaging; Neuroendocrine Tumors; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Receptors, Somatostatin | 2020 |
Topics: Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Prostatic Neoplasms; Radioisotopes; Radiotherapy; Safety | 2017 |
Prostate-specific membrane antigen theranostics: therapy with lutetium-177.
Topics: Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Ligands; Lutetium; Male; Prostate; Prostatic Neoplasms; Radioisotopes; Theranostic Nanomedicine; Treatment Outcome | 2018 |
Recent advances in theranostics and challenges for the future.
Topics: Clinical Trials as Topic; Dipeptides; Forecasting; Heterocyclic Compounds, 1-Ring; Humans; Kallikreins; Lutetium; Male; Molecular Targeted Therapy; Neuroendocrine Tumors; Peptides, Cyclic; Prostate-Specific Antigen; Prostatic Neoplasms; Radioactive Tracers; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Theranostic Nanomedicine | 2018 |
Theranostics of prostate cancer: from molecular imaging to precision molecular radiotherapy targeting the prostate specific membrane antigen.
Topics: Aged; Dipeptides; Edetic Acid; Forecasting; Gallium Isotopes; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Oligopeptides; Positron Emission Tomography Computed Tomography; Precision Medicine; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Retrospective Studies; Theranostic Nanomedicine | 2018 |
Nuclear Medicine Therapy With 223Radium-dichloride for Osseous Metastases in Prostate Carcinoma.
Topics: Bone Neoplasms; Clinical Trials as Topic; Humans; Lutetium; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radiopharmaceuticals; Radiotherapy; Radium | 2019 |
PSMA PET applications in the prostate cancer journey: from diagnosis to theranostics.
Topics: Dipeptides; Gallium Isotopes; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Membrane Glycoproteins; Neoplasm Metastasis; Organometallic Compounds; Positron Emission Tomography Computed Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiopharmaceuticals; Theranostic Nanomedicine | 2019 |
[PSMA-targeted radioligand therapy in prostate cancer].
Topics: Antigens, Surface; Dipeptides; Evidence-Based Medicine; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Lutetium; Male; Molecular Targeted Therapy; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy; Treatment Outcome | 2017 |
Lutetium
Topics: Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Prostatic Neoplasms; Radiotherapy; Radiotherapy Dosage; Safety | 2017 |
The utility of monoclonal antibodies in the imaging of prostate cancer.
Topics: Antibodies, Monoclonal; Antigens, Surface; Carboxypeptidases; Glutamate Carboxypeptidase II; Humans; Indium Radioisotopes; Lutetium; Male; Prostatic Neoplasms; Radiography; Radioisotopes; Tomography, Emission-Computed | 2002 |
Targeted systemic therapy of prostate cancer with a monoclonal antibody to prostate-specific membrane antigen.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antigens, Surface; Clinical Trials, Phase I as Topic; Cytotoxins; Disease Models, Animal; Drug Delivery Systems; Drug Evaluation, Preclinical; Extracellular Space; Fluorescent Antibody Technique; Glutamate Carboxypeptidase II; Humans; Immunoglobulin G; Lutetium; Male; Mice; Prostatic Neoplasms; Radioimmunodetection; Radioisotopes; Treatment Outcome; Yttrium Radioisotopes | 2003 |
6 trial(s) available for lutetium and Cancer of Prostate
Article | Year |
---|---|
Clinical outcomes of 177lutetium-prostate-specific membrane antigen therapy in advanced prostate cancer-a prospective pilot study in an Asian population.
Topics: Adult; Aged; Asian People; Humans; Kallikreins; Lutetium; Male; Middle Aged; Pain; Pilot Projects; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Survival Analysis; Treatment Outcome | 2020 |
Improving quality of life in patients with metastatic prostate cancer following one cycle of 177Lu-PSMA-617 radioligand therapy: a pilot study.
Topics: Aged; Aged, 80 and over; Bone Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Lutetium; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Radiopharmaceuticals; Retrospective Studies; Treatment Outcome | 2020 |
Pharmacokinetics and biodistribution of 111In- and 177Lu-labeled J591 antibody specific for prostate-specific membrane antigen: prediction of 90Y-J591 radiation dosimetry based on 111In or 177Lu?
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Body Burden; Half-Life; Humans; Indium Radioisotopes; Lutetium; Male; Metabolic Clearance Rate; Middle Aged; Organ Specificity; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Relative Biological Effectiveness; Tissue Distribution; Yttrium Radioisotopes | 2005 |
Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Bone Marrow; Cell Membrane; Humans; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging | 2005 |
Prediction of myelotoxicity based on bone marrow radiation-absorbed dose: radioimmunotherapy studies using 90Y- and 177Lu-labeled J591 antibodies specific for prostate-specific membrane antigen.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Body Burden; Bone Marrow; Bone Marrow Diseases; Dose-Response Relationship, Radiation; Humans; Lutetium; Male; Maximum Tolerated Dose; Middle Aged; Organ Specificity; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Injuries; Radioimmunotherapy; Radioisotopes; Radiotherapy Dosage; Relative Biological Effectiveness; Yttrium Radioisotopes | 2005 |
Radioimmunotherapy of prostate cancer using 90Y- and 177Lu-labeled J591 monoclonal antibodies: effect of multiple treatments on myelotoxicity.
Topics: Antibodies, Monoclonal; Blood Platelets; Bone Marrow; Dose Fractionation, Radiation; Follow-Up Studies; Humans; Lutetium; Male; Maximum Tolerated Dose; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunotherapy; Radioisotopes; Thrombocytopenia; Time Factors; Yttrium Radioisotopes | 2005 |
78 other study(ies) available for lutetium and Cancer of Prostate
Article | Year |
---|---|
Evaluation of
Topics: Animals; Chelating Agents; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Scandium; Tissue Distribution | 2021 |
Tc-99m PSMA and Lu-177 PSMA Theranostic Pair in a Patient of Metastatic Castration Resistant Prostate Cancer.
Topics: Humans; Lutetium; Male; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Precision Medicine; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radioisotopes | 2021 |
Radioligand Therapy for Metastatic Prostate Cancer.
Topics: Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Prostatic Neoplasms | 2021 |
In vitro and in vivo response of PSMA-617 radiolabeled with CA and NCA lutetium-177.
Topics: Animals; Cell Line, Tumor; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Mice, SCID; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays | 2022 |
Lutetium-177-PSMA-617 for Prostate Cancer.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes | 2021 |
Lutetium-177-PSMA-617 for Prostate Cancer.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes | 2021 |
Lutetium-177-PSMA-617 for Prostate Cancer.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes | 2021 |
Lutetium-177-PSMA-617 for Prostate Cancer. Reply.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes | 2021 |
New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177).
Topics: Albumins; Animals; Antigens, Surface; Cell Line, Tumor; Chelating Agents; Edetic Acid; Gallium Radioisotopes; Glutamate Carboxypeptidase II; Humans; Ligands; Lutetium; Male; Mice; Prostatic Neoplasms; Radioisotopes; Tissue Distribution | 2022 |
First communication on the efficacy of combined
Topics: Communication; Humans; Immunotherapy; Lutetium; Male; Prostate; Prostatic Neoplasms; Radioisotopes | 2022 |
Lutetium lu 177 vipivotide tetraxetan (Pluvicto) for prostate cancer.
Topics: Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostatic Neoplasms | 2022 |
Urinary excretion kinetics of [
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiopharmaceuticals | 2023 |
Critical Challenges in Pluvicto Therapy: Incontinent and Anticoagulated Patients.
Topics: Humans; Lutetium; Male; Precision Medicine; Prostatic Neoplasms | 2023 |
EANM procedure guidelines for radionuclide therapy with
Topics: Antigens, Surface; Documentation; Europe; Glutamate Carboxypeptidase II; Humans; Ligands; Lutetium; Male; Nuclear Medicine; Practice Guidelines as Topic; Prostatic Neoplasms; Radioisotopes; Radiometry; Safety | 2019 |
Response Prediction of
Topics: Aged; Biomarkers, Tumor; Chromogranin A; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; L-Lactate Dehydrogenase; Ligands; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome | 2020 |
Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (
Topics: Dipeptides; Follow-Up Studies; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Theranostic Nanomedicine | 2020 |
Diagnostic Utility of Lutetium-177 (Lu 177) Prostate-Specific Membrane Antigen (PSMA) Scintigraphy In Prostate Cancer Patients With PSA Rise And Negative Conventional Imaging.
Topics: Aged; Aged, 80 and over; Dipeptides; Evans Blue; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2020 |
Evaluation of [
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Radiation; GPI-Linked Proteins; Iodine Radioisotopes; Lutetium; Male; Mice; Neoplasm Proteins; Pentetic Acid; Prostatic Neoplasms; Radioimmunotherapy; Radioisotopes; Radiometry; Survival Analysis; Tissue Distribution | 2020 |
Radioligand Therapy With 177Lu-Prostate-Specific Membrane Antigen in a Patient With Non-Prostate-Specific Antigen-Secreting Metastatic Prostate Cancer.
Topics: Aged; Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Ligands; Lutetium; Male; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Treatment Outcome | 2020 |
Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy.
Topics: Animals; Antigens, Surface; Cell Line, Tumor; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Mice; Prostatic Neoplasms; Radioisotopes; Tissue Distribution | 2021 |
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant | 2021 |
PSMA-targeted therapy in prostate cancer.
Topics: Adenocarcinoma; Antibodies, Bispecific; Antibodies, Neoplasm; Antigens, Surface; Biomarkers, Tumor; Clinical Trials as Topic; Dipeptides; Docetaxel; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Immunotherapy, Adoptive; Lutetium; Male; Molecular Targeted Therapy; Nanoparticles; Neoplasm Proteins; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Randomized Controlled Trials as Topic | 2021 |
177Lu-PSMA Therapy for Metastatic Testicular Mixed Germ Cell Tumor.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Neoplasms, Germ Cell and Embryonal; Positron Emission Tomography Computed Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Testicular Neoplasms | 2021 |
Short-course
Topics: Aged; Antineoplastic Agents, Hormonal; Humans; Leuprolide; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Treatment Outcome | 2021 |
Intra-therapeutic dosimetry of [
Topics: Hormones; Humans; Lutetium; Male; Organs at Risk; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Dosage; Radiopharmaceuticals; Single Photon Emission Computed Tomography Computed Tomography; Treatment Outcome | 2022 |
The application of theranostics in different stages of prostate cancer.
Topics: Clinical Trials as Topic; Humans; Lutetium; Male; Neoplasm Staging; Precision Medicine; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy | 2021 |
The impact of repeated cycles of radioligand therapy using [
Topics: Aged; Dipeptides; Heterocyclic Compounds, 1-Ring; Hormones; Humans; Kidney; Ligands; Lutetium; Male; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Risk Factors; Time Factors; Treatment Failure | 2017 |
Topics: Albumins; Amides; Animals; Antigens, Surface; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Glutamate Carboxypeptidase II; Heterografts; Humans; Lutetium; Male; Mice; Mice, Nude; Phosphoric Acids; Prostatic Neoplasms; Radioisotopes; Treatment Outcome | 2017 |
Local Salvage Treatment of Post-brachytherapy Recurrent Prostate Cancer via Theranostic Application of PSMA-labeled Lutetium-177.
Topics: Administration, Intravenous; Antigens, Surface; Brachytherapy; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Middle Aged; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Salvage Therapy; Theranostic Nanomedicine; Treatment Outcome | 2018 |
Unusual Case of Diffuse Penile Metastasis of Prostate Cancer on 68Ga PSMA PET/CT Imaging and 177Lu PSMA Posttherapy Scintigraphy.
Topics: Aged, 80 and over; Edetic Acid; Gallium Isotopes; Gallium Radioisotopes; Humans; Lutetium; Male; Oligopeptides; Penile Neoplasms; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Radioisotopes | 2018 |
Successful handling of an accidental extravasation of 177Lu-PSMA-617 in the treatment of advanced prostate cancer.
Topics: Aged; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Manual Lymphatic Drainage; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals | 2018 |
Multidose formulation of ready-to-use
Topics: Animals; Dipeptides; Drug Compounding; Drug Stability; Drug Storage; Heterocyclic Compounds, 1-Ring; Humans; In Vitro Techniques; Lutetium; Male; Nuclear Pharmacy; Prostate-Specific Antigen; Prostatic Neoplasms; Quality Control; Radioisotopes; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Wistar; Tissue Distribution | 2018 |
Single Low-Dose Injection of Evans Blue Modified PSMA-617 Radioligand Therapy Eliminates Prostate-Specific Membrane Antigen Positive Tumors.
Topics: Animals; Dipeptides; Evans Blue; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Xenograft Model Antitumor Assays; Yttrium Radioisotopes | 2018 |
Early Experience of Rechallenge
Topics: Aged; Cohort Studies; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Lutetium; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Survival Analysis; Treatment Outcome | 2019 |
Outcome and safety of rechallenge [
Topics: Aged; Aged, 80 and over; Dipeptides; Feasibility Studies; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Safety; Survival Analysis; Treatment Outcome | 2019 |
Assessment of the radiation absorbed dose produced by
Topics: Actinium; Antigens, Surface; Bone Neoplasms; Cell Line, Tumor; Cell Nucleus; Computer Simulation; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Models, Biological; Monte Carlo Method; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Radiotherapy Dosage; Radium; Tumor Microenvironment | 2019 |
Synthesis and preclinical evaluation of the 177Lu-DOTA-PSMA(inhibitor)-Lys3-bombesin heterodimer designed as a radiotheranostic probe for prostate cancer.
Topics: Animals; Antigens, Surface; Bombesin; Cell Line, Tumor; Chemistry Techniques, Synthetic; Dimerization; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Lysine; Male; Mice; Prostatic Neoplasms; Radiochemistry; Radioisotopes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2019 |
DNA damage in blood leucocytes of prostate cancer patients during therapy with
Topics: Aged; Aged, 80 and over; Dipeptides; DNA Breaks, Double-Stranded; DNA Damage; Dose-Response Relationship, Radiation; Heterocyclic Compounds, 1-Ring; Humans; Leukocytes; Lutetium; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy Dosage | 2019 |
The use of molecular volumetric parameters for the evaluation of Lu-177 PSMA I&T therapy response and survival.
Topics: Aged; Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Radioisotopes; Retrospective Studies; Survival Analysis; Treatment Outcome; Tumor Burden | 2019 |
Concentration-dependent effects of dutasteride on prostate-specific membrane antigen (PSMA) expression and uptake of
Topics: 5-alpha Reductase Inhibitors; Antigens, Surface; Cell Line, Tumor; Dipeptides; Dose-Response Relationship, Drug; Dutasteride; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Receptors, Androgen; Up-Regulation | 2019 |
A pilot study of prostate-specific membrane antigen (PSMA) dynamics in men undergoing treatment for advanced prostate cancer.
Topics: Aged; Aged, 80 and over; Antigens, Surface; Bridged-Ring Compounds; Dipeptides; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; RNA, Messenger; Taxoids; Treatment Outcome | 2019 |
Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy.
Topics: Animals; Antineoplastic Agents; Autoradiography; Disease Models, Animal; Female; Hypoxia; Lutetium; Male; Mice; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Bombesin; Tissue Distribution | 2019 |
Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin.
Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Female; Gene Expression Regulation, Neoplastic; Humans; Lutetium; Male; Mice; Molecular Targeted Therapy; Oligopeptides; Prostatic Neoplasms; Radioisotopes; Receptors, Bombesin; Sirolimus | 2013 |
177Lu-labeled RGD-BBN heterodimeric peptide for targeting prostate carcinoma.
Topics: Animals; Aza Compounds; Bombesin; Cell Line, Tumor; Dimerization; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Molecular Targeted Therapy; Oligopeptides; Prostatic Neoplasms; Radiation Dosage; Radiochemistry; Radioisotopes | 2013 |
Radiolabeled antagonistic bombesin peptidomimetics for tumor targeting.
Topics: Amino Acid Sequence; Bombesin; Cell Line, Tumor; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Lutetium; Male; Peptide Fragments; Peptidomimetics; Prostatic Neoplasms; Proteolysis; Radioisotopes; Tomography, Emission-Computed, Single-Photon; Triazoles | 2014 |
uPAR targeted radionuclide therapy with (177)Lu-DOTA-AE105 inhibits dissemination of metastatic prostate cancer.
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Disease-Free Survival; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Inhibitory Concentration 50; Ligands; Lutetium; Male; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Oligopeptides; Positron-Emission Tomography; Prostatic Neoplasms; Protein Binding; Radioisotopes; Receptors, Urokinase Plasminogen Activator; Recombinant Proteins; Treatment Outcome; X-Ray Microtomography | 2014 |
In vivo enzyme inhibition improves the targeting of [177Lu]DOTA-GRP(13-27) in GRPR-positive tumors in mice.
Topics: Animals; Cell Line, Tumor; Gastrin-Releasing Peptide; Glycopeptides; Heterografts; Humans; Lutetium; Male; Mice; Mice, Nude; Neprilysin; Peptide Fragments; Prostatic Neoplasms; Protease Inhibitors; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Bombesin; Tissue Distribution | 2014 |
Biological evaluation of (177)Lu-labeled DOTA-Ala(SO3H)-Aminooctanoyl-Gln-Trp-Ala-Val-N methyl Gly-His-Statine-Leu-NH2 for gastrin-releasing peptide receptor-positive prostate tumor targeting.
Topics: Amino Acids; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Lutetium; Male; Mice; Oligopeptides; Prostatic Neoplasms; Radioisotopes; Receptors, Bombesin; Tissue Distribution | 2015 |
Preclinical pharmacokinetic, biodistribution, imaging and therapeutic efficacy of (177)Lu-Labeled glycated bombesin analogue for gastrin-releasing peptide receptor-positive prostate tumor targeting.
Topics: Aminobenzoates; Animals; Bombesin; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glycosylation; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Prostatic Neoplasms; Radioisotopes; Receptors, Bombesin; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2015 |
Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.
Topics: Animals; Antigens, Surface; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Dipeptides; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Peptides; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution | 2015 |
68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies.
Topics: Aged; Anhydrides; Animals; Antigens, Surface; Cell Line, Tumor; Contrast Media; Coordination Complexes; Female; Gallium Radioisotopes; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Inhibitory Concentration 50; Kinetics; Lutetium; Male; Mice; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; Oligopeptides; Positron-Emission Tomography; Prostatic Neoplasms; Radiometry; Radiotherapy | 2015 |
SNMMI 2015 Image of the Year.
Topics: Antigens, Surface; Awards and Prizes; Baltimore; Dipeptides; Gallium; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; History, 21st Century; Humans; Lutetium; Male; Neoplasm Metastasis; Nuclear Medicine; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging; Societies, Medical | 2015 |
Marked Response to 177Lu Prostate-Specific Membrane Antigen Treatment in Patient With Metastatic Prostate Cancer.
Topics: Edetic Acid; Gallium Isotopes; Gallium Radioisotopes; Humans; Lutetium; Male; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Oligopeptides; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tomography, X-Ray Computed | 2016 |
Lutetium-177 Labeled Therapeutics: ¹⁷⁷Lu-PSMA is Set to Redefine Prostate Cancer Treatment.
Topics: Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Lutetium; Male; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals | 2016 |
Radiosensitivity of Prostate Cancer Cell Lines for Irradiation from Beta Particle-emitting Radionuclide ¹⁷⁷Lu Compared to Alpha Particles and Gamma Rays.
Topics: Alpha Particles; Americium; Beta Particles; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Lutetium; Male; Prostatic Neoplasms; Radiation Tolerance; Radioisotopes | 2016 |
Lacrimal Glands May Represent Organs at Risk for Radionuclide Therapy of Prostate Cancer with [(177)Lu]DKFZ-PSMA-617.
Topics: Aged; Demography; Dose-Response Relationship, Radiation; Humans; Lacrimal Apparatus; Lutetium; Male; Middle Aged; Organometallic Compounds; Organs at Risk; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Tissue Distribution; Whole Body Imaging | 2016 |
Response and Tolerability of a Single Dose of 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer: A Multicenter Retrospective Analysis.
Topics: Adult; Aged; Aged, 80 and over; Dipeptides; Dose-Response Relationship, Drug; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Lymphatic Metastasis; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Injuries; Radiopharmaceuticals; Retrospective Studies; Treatment Outcome | 2016 |
Evaluation of radiation safety in (177)Lu-PSMA therapy and development of outpatient treatment protocol.
Topics: Caregivers; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Occupational Exposure; Outpatients; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Dosage; Radiation Monitoring; Radiotherapy Dosage; Safety Management; Thermoluminescent Dosimetry; Time Factors; Treatment Outcome | 2016 |
Clinical translation of (177)Lu-labeled PSMA-617: Initial experience in prostate cancer patients.
Topics: Animals; Cell Line, Tumor; Dipeptides; Drug Stability; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Dosage; Rats; Rats, Wistar; Tissue Distribution; Translational Research, Biomedical | 2016 |
Prospects of medium specific activity (177) Lu in targeted therapy of prostate cancer using (177) Lu-labeled PSMA inhibitor.
Topics: Aged; Antigens, Surface; Dipeptides; Drug Stability; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Quality Control; Radiochemistry; Radioisotopes | 2016 |
Formulation of clinical-scale
Topics: Clinical Trials as Topic; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2016 |
Investigating the Effect of Ligand Amount and Injected Therapeutic Activity: A Simulation Study for 177Lu-Labeled PSMA-Targeting Peptides.
Topics: Aged; Antigens, Surface; Computer Simulation; Dose-Response Relationship, Drug; Drug Delivery Systems; Glutamate Carboxypeptidase II; Humans; Kidney; Ligands; Lutetium; Male; Maximum Tolerated Dose; Middle Aged; Peptides; Prostatic Neoplasms; Radioisotopes; Retrospective Studies; Salivary Glands | 2016 |
Radioligand therapy with
Topics: Clinical Trials as Topic; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2016 |
German Multicenter Study Investigating 177Lu-PSMA-617 Radioligand Therapy in Advanced Prostate Cancer Patients.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Causality; Comorbidity; Dipeptides; Germany; Hematologic Diseases; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Prevalence; Prostate-Specific Antigen; Prostatic Neoplasms; Radiation Injuries; Radiopharmaceuticals; Retrospective Studies; Risk Factors; Treatment Outcome | 2017 |
From NETTER to PETTER: PSMA-Targeted Radioligand Therapy.
Topics: Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostate-Specific Antigen; Prostatic Neoplasms | 2017 |
Therapeutic efficacy of 177Lu-CHX-A''-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Docetaxel; Dose-Response Relationship, Radiation; Enzyme Inhibitors; ErbB Receptors; Humans; Isothiocyanates; Lutetium; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pentetic Acid; Phosphorylation; Prostatic Neoplasms; Quinazolines; Radiation-Sensitizing Agents; Radioimmunotherapy; Radioisotopes; Taxoids; Tyrphostins; Xenograft Model Antitumor Assays | 2009 |
Peptide-targeted diagnostics and radiotherapeutics.
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Cell Line; ErbB Receptors; Gadolinium; Humans; Lutetium; Male; Molecular Sequence Data; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Prostatic Neoplasms; Protein Binding; Radiopharmaceuticals; Rats; Receptors, G-Protein-Coupled; Tuftsin | 2009 |
Anti-prostate-specific membrane antigen-based radioimmunotherapy for prostate cancer.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Screening Assays, Antitumor; Humans; Lutetium; Male; Mice; Patient Selection; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunotherapy; Radioisotopes; Radiopharmaceuticals | 2010 |
Multimodality imaging and preclinical evaluation of 177Lu-AMBA for human prostate tumours in a murine model.
Topics: Animals; Cell Line, Tumor; Humans; Isotope Labeling; Luminescent Measurements; Lutetium; Male; Mice; Mice, SCID; Oligopeptides; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2010 |
Alpha- versus beta-particle radiopeptide therapy in a human prostate cancer model (213Bi-DOTA-PESIN and 213Bi-AMBA versus 177Lu-DOTA-PESIN).
Topics: Alpha Particles; Animals; Beta Particles; Bismuth; Female; Humans; Lutetium; Male; Mice; Mice, Nude; Oligopeptides; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Xenograft Model Antitumor Assays | 2011 |
Novel series of (177)Lu-labeled bombesin derivatives with amino acidic spacers for selective targeting of human PC-3 prostate tumor cells.
Topics: Animals; Bombesin; Cell Line, Tumor; Drug Stability; Humans; Lutetium; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2011 |
Adenocarcinoma cells exposed in vitro to Navelbine or Taxol increase Ep-CAM expression through a novel mechanism.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Cell Adhesion Molecules; Cell Survival; Chromium; Colonic Neoplasms; Epithelial Cell Adhesion Molecule; Female; G2 Phase; Humans; In Vitro Techniques; Lutetium; Male; Mice; Mice, Nude; Mitosis; Paclitaxel; Prostatic Neoplasms; Tumor Cells, Cultured; Vinblastine; Vinorelbine | 2003 |
Synthesis and evaluation of bombesin derivatives on the basis of pan-bombesin peptides labeled with indium-111, lutetium-177, and yttrium-90 for targeting bombesin receptor-expressing tumors.
Topics: Animals; Bombesin; Drug Stability; Humans; Indium Radioisotopes; Isotope Labeling; Lutetium; Male; Pancreatic Neoplasms; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Rats; Receptors, Bombesin; Tissue Distribution; Yttrium Radioisotopes | 2004 |
Radioimmunotherapy of prostate cancer: does tumor size matter?
Topics: Antibodies, Monoclonal; Humans; Lutetium; Male; Prostatic Neoplasms; Radioimmunotherapy; Radioisotopes; Yttrium Radioisotopes | 2005 |
Evaluation of combined (177)Lu-DOTA-8-AOC-BBN (7-14)NH(2) GRP receptor-targeted radiotherapy and chemotherapy in PC-3 human prostate tumor cell xenografted SCID mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Chemical Analysis; Bombesin; Docetaxel; Estramustine; Female; Lutetium; Male; Mice; Mice, SCID; Models, Molecular; Peptide Fragments; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Receptors, Bombesin; Taxoids; Tumor Protein, Translationally-Controlled 1; Xenograft Model Antitumor Assays | 2006 |
177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer.
Topics: Animals; Binding, Competitive; Bombesin; Cell Line, Tumor; Disease Progression; Gene Expression Regulation; Humans; Lutetium; Male; Mice; Mice, Nude; Oligopeptides; Peptides; Prostatic Neoplasms; Radioisotopes; Receptors, Bombesin | 2006 |
DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours.
Topics: Animals; Bombesin; Cell Line, Tumor; Gallium Radioisotopes; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging; Receptors, Bombesin | 2007 |
Pm-149 DOTA bombesin analogs for potential radiotherapy. in vivo comparison with Sm-153 and Lu-177 labeled DO3A-amide-betaAla-BBN(7-14)NH(2).
Topics: Animals; Bombesin; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Metabolic Clearance Rate; Metals, Rare Earth; Mice; Peptide Fragments; Promethium; Prostatic Neoplasms; Radiopharmaceuticals; Reproducibility of Results; Samarium; Sensitivity and Specificity; Tissue Distribution | 2002 |