luteolin and Hypersensitivity

luteolin has been researched along with Hypersensitivity* in 2 studies

Other Studies

2 other study(ies) available for luteolin and Hypersensitivity

Article	Year
Discovery and development of spleen tyrosine kinase (SYK) inhibitors. Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Topics: Animals; Autoimmune Diseases; Drug Discovery; Enzyme Inhibitors; Humans; Hypersensitivity; Intracellular Signaling Peptides and Proteins; Mice; Protein-Tyrosine Kinases; Structure-Activity Relationship; Syk Kinase; ZAP-70 Protein-Tyrosine Kinase	2012
New inhibitors for expression of IgE receptor on human mast cell. Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7 Exploration for inhibitors against expression of IgE receptor (Fc epsilonRI) on human mast cell, a significant trigger to acute and chronic allergic symptoms, disclosed epigallocatechin gallate (EGCG), epicatechin gallate, and gallocatechin gallate as active principles. Additionally, the anthocyanidin, delphinidin, and the flavone, tricetinidin, possessing a pyrogallol function were also revealed to suppress expression of Fc epsilonRI. Structure-activity relationship analysis among catechins, anthocyanidins, and flavones revealed the pyrogallol moiety to be crucial for biological potency. Furthermore, EGCG was clarified to reduce generation of gamma-chain subunit to suppress expression of Fc epsilonRI on human mast cells. Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE	2010

Article

Year

Discovery and development of spleen tyrosine kinase (SYK) inhibitors.

Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

Topics: Animals; Autoimmune Diseases; Drug Discovery; Enzyme Inhibitors; Humans; Hypersensitivity; Intracellular Signaling Peptides and Proteins; Mice; Protein-Tyrosine Kinases; Structure-Activity Relationship; Syk Kinase; ZAP-70 Protein-Tyrosine Kinase

2012

New inhibitors for expression of IgE receptor on human mast cell.

Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

Exploration for inhibitors against expression of IgE receptor (Fc epsilonRI) on human mast cell, a significant trigger to acute and chronic allergic symptoms, disclosed epigallocatechin gallate (EGCG), epicatechin gallate, and gallocatechin gallate as active principles. Additionally, the anthocyanidin, delphinidin, and the flavone, tricetinidin, possessing a pyrogallol function were also revealed to suppress expression of Fc epsilonRI. Structure-activity relationship analysis among catechins, anthocyanidins, and flavones revealed the pyrogallol moiety to be crucial for biological potency. Furthermore, EGCG was clarified to reduce generation of gamma-chain subunit to suppress expression of Fc epsilonRI on human mast cells.

Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010