lumacaftor has been researched along with Polycystic-Kidney--Autosomal-Recessive* in 1 studies
1 other study(ies) available for lumacaftor and Polycystic-Kidney--Autosomal-Recessive
| Article | Year |
|---|---|
Ameliorating liver disease in an autosomal recessive polycystic kidney disease mouse model.
Systemic and portal hypertension, liver fibrosis, and hepatomegaly are manifestations associated with autosomal recessive polycystic kidney disease (ARPKD), which is caused by malfunctions of fibrocystin/polyductin (FPC). The goal is to understand how liver pathology occurs and to devise therapeutic strategies to treat it. We injected 5-day-old Topics: Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Heat-Shock Proteins; Humans; Liver Cirrhosis; Mice; Polycystic Kidney, Autosomal Recessive; Receptors, Cell Surface | 2023 |