Page last updated: 2024-08-24

lufironil and Cirrhoses, Experimental Liver

lufironil has been researched along with Cirrhoses, Experimental Liver in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (81.82)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kayano, K; Kubota, M; Mori, K; Okita, K; Sakaida, I; Takenaka, K1
Okita, K; Sakaida, I1
Kayano, K; Kubota, M; Matsumura, Y; Okita, K; Sakaida, I; Takenaka, K1
Ishihara, T; Kimura, T; Matsumura, Y; Okita, K; Sakaida, I; Uchida, K1
Bickel, M; Bissell, DM; Gerl, M; Guenzler, V; Wang, SS; Wang, YJ1
Hironaka, K; Okita, K; Sakaida, I; Uchida, K1
Bickel, M; Hyder, A; Juergensen, A; Laue, C; Marx, SK; Schrezenmeir, J; Zhang, WJ1
Hino, K; Okita, K; Sakaida, I1
Böker, K; Günzler, V; Kaule, G; Ohlendorf, S; Schmidt, E; Schwarting, G1
Baader, E; Bickel, M; Brocks, DG; Engelbart, K; Günzler, V; Schmidts, HL; Vogel, GH1
Badder, E; Eckert, HG; Kellner, HM; Kürzel, GU; Volz, M1

Reviews

1 review(s) available for lufironil and Cirrhoses, Experimental Liver

ArticleYear
Current strategies for chemoprevention of hepatocellular carcinoma.
    Oncology, 2002, Volume: 62 Suppl 1

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Chemoprevention; Drugs, Chinese Herbal; Forecasting; Hepatitis B; Hepatitis C; Humans; Interferons; Liver Cirrhosis, Experimental; Liver Neoplasms; Pyridines; Tretinoin

2002

Other Studies

10 other study(ies) available for lufironil and Cirrhoses, Experimental Liver

ArticleYear
Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: Amino Acids; Animals; Choline Deficiency; Diet; Disease Models, Animal; Glutathione Transferase; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Procollagen-Proline Dioxygenase; Prodrugs; Pyridines; Rats; Rats, Wistar

1994
New prolyl 4-hydroxylase inhibitor reduces procollagen gene expression and enzyme-altered lesions in rat liver cirrhosis.
    Journal of gastroenterology and hepatology, 1995, Volume: 10 Suppl 1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Northern; Choline; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Liver; Liver Cirrhosis, Experimental; Male; Procollagen; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Wistar; RNA, Messenger

1995
The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:4

    Topics: Amino Acids; Animals; Choline Deficiency; Gene Expression; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Procollagen; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Wistar; RNA, Messenger

1996
Prolyl 4-hydroxylase inhibitor (HOE 077) inhibits pig serum-induced rat liver fibrosis by preventing stellate cell activation.
    Journal of hepatology, 1997, Volume: 27, Issue:1

    Topics: Animals; Biomarkers; Blood; Blotting, Northern; Enzyme Inhibitors; Hydroxyproline; Liver; Liver Cirrhosis, Experimental; Male; Microscopy, Electron; Microscopy, Immunoelectron; Procollagen; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Swine

1997
Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: differential effects in males and females.
    The American journal of pathology, 1998, Volume: 152, Issue:1

    Topics: Animals; Carbon Tetrachloride; Collagen; Female; Liver; Liver Cirrhosis, Experimental; Male; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sex Characteristics

1998
Prolyl 4-hydroxylase inhibitor (HOE 077) prevents TIMP-1 gene expression in rat liver fibrosis.
    Journal of gastroenterology, 1999, Volume: 34, Issue:3

    Topics: Animals; Blotting, Northern; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Liver Cirrhosis, Experimental; Male; Procollagen; Pyridines; Rats; Rats, Wistar; Reference Values; Tissue Inhibitor of Metalloproteinase-1

1999
HOE 077 reduces fibrotic overgrowth around the barium alginate microcapsules.
    Transplantation proceedings, 2000, Volume: 32, Issue:1

    Topics: Alginates; Animals; Barium; Capsules; Cell Separation; Cell Survival; Fibrosis; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred BALB C; Prodrugs; Pyridines; Swine; Transplantation, Heterotopic

2000
[Experimental studies of the inhibition of fibrogenesis].
    Zeitschrift fur Gastroenterologie, 1992, Volume: 30 Suppl 1

    Topics: Animals; Colchicine; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Liver; Liver Cirrhosis, Experimental; Male; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Wistar

1992
Beneficial effects of inhibitors of prolyl 4-hydroxylase in CCl4-induced fibrosis of the liver in rats.
    Journal of hepatology, 1991, Volume: 13 Suppl 3

    Topics: Animals; Bile Acids and Salts; Bilirubin; Carbon Tetrachloride Poisoning; Collagen; Connective Tissue; Female; Liver; Liver Cirrhosis, Experimental; Procollagen; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Inbred Strains; Reference Values; Tensile Strength; Wound Healing

1991
Pharmacokinetics and metabolism of HOE 077. Preclinical studies.
    Journal of hepatology, 1991, Volume: 13 Suppl 3

    Topics: Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Carbon Tetrachloride Poisoning; Dogs; Female; Liver; Liver Cirrhosis, Experimental; Liver Function Tests; Male; Metabolic Clearance Rate; Procollagen-Proline Dioxygenase; Pyridines; Rats; Rats, Inbred Strains; Tissue Distribution

1991