lucifer-yellow and Abnormalities--Radiation-Induced

lucifer-yellow has been researched along with Abnormalities--Radiation-Induced* in 1 studies

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1 other study(ies) available for lucifer-yellow and Abnormalities--Radiation-Induced

ArticleYear
Developmental abnormalities of corticospinal tract neurons in prenatally irradiated rats: a study using retrograde labeling with Fast blue and intracellular Lucifer yellow staining.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    The effect of prenatal X-irradiation on the ontogenesis of corticospinal tract (CST) neurons was examined in rats using retrograde labeling with Fast blue and intracellular Lucifer yellow staining. In prenatally irradiated rats, the cortical laminar architecture of the CST neurons was confused and many cells demonstrated migratory disturbances. Migratory-disordered CST neurons at deeper cortical levels resembled pyramidal cells, but their apical dendrites were oriented in various directions and the development of their dendrites was poor. Migratory-disordered CST neurons near the ependymal layer demonstrated round somata and many thin dendrites with spokewise radiation, suggesting a maturation disturbance. These results suggested that prenatal X-irradiation impeded the migration and maturation of CST neurons. These findings may form the basis for analyzing the mechanisms of radiation-induced mental retardation and behavioral changes.

    Topics: Abnormalities, Radiation-Induced; Amidines; Animals; Cerebral Cortex; Corpus Callosum; Dendrites; Female; Histocytochemistry; Isoquinolines; Neurons; Pregnancy; Rats; Rats, Wistar; Spinal Cord

1993