Compounds > lubiprostone

Page last updated: 2024-09-04

lubiprostone and Cystic Fibrosis

lubiprostone has been researched along with Cystic Fibrosis in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (44.44)	29.6817
2010's	5 (55.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hawkins, CE; Henderson, MJ; MacDonald, KD; McKenzie, KR; Vij, N; Zeitlin, PL	1
Cuthbert, AW; Joo, NS; Wine, JJ	1
Kapoor, S	1
Anderson, PJ; O'Brien, CE; Stowe, CD	2
De Lisle, RC; Mueller, R; Roach, E	1
Cuthbert, AW	1
Kang, PW; Kovbasnjuk, O; Lee, S; Schiffhauer, ES; Vij, N; Walker, D; Zeitlin, PL	1
Cope, G; Cuthbert, AW; MacVinish, LJ; Ropenga, A	1

Trials

1 trial(s) available for lubiprostone and Cystic Fibrosis

Article	Year
Lubiprostone for constipation in adults with cystic fibrosis: a pilot study. The Annals of pharmacotherapy, 2011, Volume: 45, Issue:9 Topics: Adult; Alprostadil; Chloride Channels; CLC-2 Chloride Channels; Constipation; Cystic Fibrosis; Female; Humans; Lubiprostone; Male; Pilot Projects; Treatment Outcome; Young Adult	2011

Other Studies

8 other study(ies) available for lubiprostone and Cystic Fibrosis

Article	Year
Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:5 Topics: Adenosine Triphosphate; Administration, Topical; Alprostadil; Animals; Biological Transport; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electric Conductivity; Epithelium; Gene Expression Regulation; Lubiprostone; Membrane Potentials; Mice; Mice, Knockout; Respiratory System; RNA, Messenger; Subcellular Fractions	2008
Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans. American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:5 Topics: Alprostadil; Animals; Anions; Carbachol; Chloride Channels; Cystic Fibrosis; Dose-Response Relationship, Drug; Electric Conductivity; Exocrine Glands; Humans; In Vitro Techniques; Lubiprostone; Mucous Membrane; Muscle Contraction; Sheep; Sus scrofa; Trachea	2009
Lubiprostone: clinical applications beyond constipation. World journal of gastroenterology, 2009, Mar-07, Volume: 15, Issue:9 Topics: Alprostadil; Animals; Chloride Channels; Constipation; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Laxatives; Lubiprostone; Muscle Contraction	2009
Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:3 Topics: Adult; Alprostadil; Chloride Channels; Constipation; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Intestinal Obstruction; Lubiprostone; Male; Secondary Prevention; Treatment Outcome; Young Adult	2010
Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype. BMC gastroenterology, 2010, Sep-15, Volume: 10 Topics: Alprostadil; Animals; Bacteria; Bacterial Load; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Immunity, Innate; Intestine, Small; Lubiprostone; Mice; Mice, Inbred C57BL; Phenotype	2010
Lubiprostone targets prostanoid EP₄ receptors in ovine airways. British journal of pharmacology, 2011, Volume: 162, Issue:2 Topics: Adenylyl Cyclases; Alprostadil; Animals; Chloride Channels; CLC-2 Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Lubiprostone; Molecular Targeted Therapy; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Mucosa; Sheep; Thiophenes; Trachea; Triazoles	2011
Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia. American journal of physiology. Lung cellular and molecular physiology, 2013, Mar-01, Volume: 304, Issue:5 Topics: Alprostadil; Animals; Chloride Channels; CLC-2 Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Ion Transport; Lubiprostone; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nasal Mucosa; Scorpion Venoms	2013
Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR. British journal of pharmacology, 2007, Volume: 150, Issue:8 Topics: Adenylyl Cyclases; Alprostadil; Carbachol; Cell Line; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Fatty Acids; Genetic Vectors; Humans; Lubiprostone; Lung; Membrane Potentials; Muscarinic Agonists; Retroviridae; RNA Interference; RNA, Small Interfering; Time Factors	2007