Page last updated: 2024-08-24

lubeluzole and Stroke

lubeluzole has been researched along with Stroke in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's10 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anger, T; Madge, DJ; Mulla, M; Riddall, D1
Bechtel, WD; Carter, AJ; Grauert, M; Nar, H; Stransky, W; Weiser, T1
Diener, HC; Wessel, TC1
Donnan, GA; Ly, JV; Zavala, JA1
De Keyser, J; Koch, MW; Luijckx, GJ; Stewart, RE; Uyttenboogaart, M; Vroomen, PC1
Bankhead, C1
Cortens, M; Diener, HC; Ford, G; Grotta, J; Hacke, W; Kaste, M; Koudstaal, PJ; Wessel, T1
Fisher, M; Schaebitz, W1
Grotta, J2
Sareen, D1

Reviews

5 review(s) available for lubeluzole and Stroke

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke

2001
Nitrous oxide modulator: lubeluzole.
    Current medical research and opinion, 2002, Volume: 18 Suppl 2

    Topics: Aged; Brain Ischemia; Humans; Neuroprotective Agents; Nitrous Oxide; Piperidines; Stroke; Thiazoles

2002
Neuroprotection and thrombolysis: combination therapy in acute ischaemic stroke.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:12

    Topics: Animals; Benzenesulfonates; Brain; Brain Ischemia; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; GABA Agonists; Humans; Neuroprotective Agents; Nitrogen Oxides; Piperidines; Randomized Controlled Trials as Topic; Sodium Channel Blockers; Stroke; Thiazoles; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

2006
An overview of acute stroke therapy: past, present, and future.
    Archives of internal medicine, 2000, Nov-27, Volume: 160, Issue:21

    Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy

2000
Neuroprotective agents in acute ischemic stroke.
    The Journal of the Association of Physicians of India, 2002, Volume: 50

    Topics: Acute Disease; Adult; Aged; Animals; Antioxidants; Calcium Channel Blockers; Chlormethiazole; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Forecasting; GABA Modulators; Guanidines; Humans; Imidazoles; Middle Aged; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pipecolic Acids; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Stroke; Thiazoles

2002

Trials

4 trial(s) available for lubeluzole and Stroke

ArticleYear
Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke.
    Brain : a journal of neurology, 2007, Volume: 130, Issue:Pt 6

    Topics: Acute Disease; Aged; Aged, 80 and over; Blood Glucose; Brain Infarction; Female; Humans; Hyperglycemia; Male; Middle Aged; Neuroprotective Agents; Piperidines; Prognosis; Severity of Illness Index; Stroke; Thiazoles; Treatment Outcome

2007
Lubeluzole in acute ischemic stroke treatment: A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo.
    Stroke, 2000, Volume: 31, Issue:11

    Topics: Acute Disease; Aged; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Neuroprotective Agents; Piperidines; Placebos; Severity of Illness Index; Stroke; Thiazoles; Treatment Outcome

2000
Combination therapy stroke trial. rt-PA +/- lubeluzole.
    Annals of the New York Academy of Sciences, 2001, Volume: 939

    Topics: Drug Therapy, Combination; Feasibility Studies; Humans; Neuroprotective Agents; Piperidines; Stroke; Thiazoles

2001
Combination Therapy Stroke Trial: recombinant tissue-type plasminogen activator with/without lubeluzole.
    Cerebrovascular diseases (Basel, Switzerland), 2001, Volume: 12, Issue:3

    Topics: Activities of Daily Living; Aged; Cerebral Hemorrhage; Double-Blind Method; Feasibility Studies; Female; Glasgow Coma Scale; Humans; Male; Neuroprotective Agents; Piperidines; Plasminogen Activators; Prospective Studies; Recombinant Proteins; Stroke; Thiazoles; Tissue Plasminogen Activator

2001

Other Studies

3 other study(ies) available for lubeluzole and Stroke

ArticleYear
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Benzomorphans; Cerebral Cortex; Corpus Striatum; Crystallography, X-Ray; Electroshock; Glutamic Acid; In Vitro Techniques; Male; Mice; Neuroprotective Agents; Radioligand Assay; Rats; Seizures; Sodium Channel Blockers; Stroke; Structure-Activity Relationship; Thromboembolism; Veratridine

2002
Lubeluzole. JK 8792, R 87926, Prosynap.
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Acute Disease; Brain Ischemia; Drugs, Investigational; Humans; Neuroprotective Agents; Piperidines; Stroke; Thiazoles

1999
What's new with neuroprotective agents in stroke?
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Animals; Chlormethiazole; Cytidine Diphosphate Choline; Drugs, Investigational; Humans; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles

1999