lubeluzole has been researched along with Brain Ischemia in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (55.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diener, HC; Wessel, TC | 1 |
| Brantley, DR; Deyo, DJ; Disterhoft, JF; Mueller, RN; Zornow, MH | 1 |
| Engel, DC; Maas, AI; Slemmer, JE; Vlug, AS; Weber, JT | 1 |
| Donnan, GA; Ly, JV; Zavala, JA | 1 |
| De Keyser, J; Diener, HC; Hacke, W; Hantson, L; Hennerici, M; Rådberg, J | 1 |
| Aronowski, J; Grotta, JC; Strong, R | 1 |
| Ashton, D; Clincke, G; Marrannes, R; Van Reempts, J; Willems, R; Wynants, J | 1 |
| Borgers, M; Haseldonckx, M; Van de Ven, M; Van Reempts, J; Wouters, L | 1 |
| Grotta, J | 1 |
| Culmsee, C; Junker, V; Krieglstein, J; Semkova, I; Wolz, P | 1 |
| Lodder, J | 1 |
| Beard, DC; Billingsley, ML; Burkhart, KK; Lehman, RA | 1 |
| Grotta, J; Hickenbottom, SL | 1 |
| Demchuk, AM; Hantson, L; Jauss, M; Kasner, SE; Krieger, DW | 1 |
| Fisher, M; Schaebitz, W | 1 |
| Que, M; Witte, OW; Zilles, K | 1 |
| Koinig, H; Rueda, C; Vornik, V; Zornow, MH | 1 |
| Conti, M; Gandolfo, C; Sandercock, P | 1 |
| Berger, R; Garnier, Y; Jensen, A; Löbbert, T | 1 |
5 review(s) available for lubeluzole and Brain Ischemia
| Article | Year |
|---|---|
Nitrous oxide modulator: lubeluzole.
Topics: Aged; Brain Ischemia; Humans; Neuroprotective Agents; Nitrous Oxide; Piperidines; Stroke; Thiazoles | 2002 |
Neuroprotection and thrombolysis: combination therapy in acute ischaemic stroke.
Topics: Animals; Benzenesulfonates; Brain; Brain Ischemia; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; GABA Agonists; Humans; Neuroprotective Agents; Nitrogen Oxides; Piperidines; Randomized Controlled Trials as Topic; Sodium Channel Blockers; Stroke; Thiazoles; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 2006 |
Neuroprotective therapy.
Topics: Brain Ischemia; Calcium Channel Blockers; Clinical Trials as Topic; Cytoprotection; Excitatory Amino Acid Antagonists; Humans; Neuroprotective Agents; Piperidines; Thiazoles | 1998 |
An overview of acute stroke therapy: past, present, and future.
Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy | 2000 |
Lubeluzole for acute ischaemic stroke.
Topics: Acute Disease; Brain Ischemia; Humans; Neuroprotective Agents; Piperidines; Thiazoles | 2002 |
3 trial(s) available for lubeluzole and Brain Ischemia
| Article | Year |
|---|---|
Lubeluzole in acute ischemic stroke. A double-blind, placebo-controlled phase II trial. Lubeluzole International Study Group.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Agents; Carotid Artery Diseases; Cerebrovascular Disorders; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Logistic Models; Male; Middle Aged; Multivariate Analysis; Piperidines; Placebos; Safety; Thiazoles | 1996 |
Lubeluzole treatment of acute ischemic stroke. The US and Canadian Lubeluzole Ischemic Stroke Study Group.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Cerebrovascular Disorders; Double-Blind Method; Female; Heart Diseases; Humans; Male; Middle Aged; Mortality; Neuroprotective Agents; Piperidines; Survival Analysis; Thiazoles; Treatment Outcome | 1997 |
Early clinical and radiological predictors of fatal brain swelling in ischemic stroke.
Topics: Acute Disease; Aged; Brain Edema; Brain Ischemia; Case-Control Studies; Cerebral Arteries; Female; Hospital Mortality; Humans; Male; Middle Aged; Neuroprotective Agents; Piperidines; Prognosis; Risk Factors; Severity of Illness Index; Thiazoles; Tomography, X-Ray Computed | 1999 |
12 other study(ies) available for lubeluzole and Brain Ischemia
| Article | Year |
|---|---|
Lubeluzole and conditioned learning after cerebral ischemia.
Topics: Animals; Brain Ischemia; Conditioning, Psychological; Learning; Male; Piperidines; Rabbits; Thiazoles | 2003 |
Combined effects of mechanical and ischemic injury to cortical cells: secondary ischemia increases damage and decreases effects of neuroprotective agents.
Topics: Animals; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Mice; Mitogen-Activated Protein Kinase 1; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Physical Stimulation; Piperidines; Stress, Mechanical; Superoxide Dismutase; Thiazoles | 2005 |
Treatment of experimental focal ischemia in rats with lubeluzole.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Neuroprotective Agents; Piperidines; Rats; Thiazoles | 1996 |
Altered Na(+)-channel function as an in vitro model of the ischemic penumbra: action of lubeluzole and other neuroprotective drugs.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Cerebrovascular Circulation; Extracellular Space; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Neuroprotective Agents; Piperidines; Pyramidal Cells; Sodium Channels; Thiazoles; Veratridine | 1997 |
Protection with lubeluzole against delayed ischemic brain damage in rats. A quantitative histopathologic study.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Carotid Stenosis; Cell Death; Drug Evaluation, Preclinical; Hippocampus; Ligation; Male; Neurons; Neuroprotective Agents; Piperidines; Rats; Rats, Wistar; Shock; Thiazoles; Time Factors | 1997 |
Lubeluzole protects hippocampal neurons from excitotoxicity in vitro and reduces brain damage caused by ischemia.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Ischemia; Cells, Cultured; Excitatory Amino Acids; Glutamic Acid; Hippocampus; Male; Mice; Neurons; Neuroprotective Agents; Piperidines; Rats; Rats, Inbred F344; Stereoisomerism; Thiazoles | 1998 |
Lubeluzole treatment of acute ischemic stroke.
Topics: Acute Disease; Brain Ischemia; Cardiovascular Agents; Cerebrovascular Disorders; Humans; Piperidines; Thiazoles | 1998 |
Alterations in tau phosphorylation in rat and human neocortical brain slices following hypoxia and glucose deprivation.
Topics: Animals; Brain Ischemia; Cell Hypoxia; Enzyme Inhibitors; Glucose; Humans; Hypoglycemia; Hypoxia, Brain; Male; Neocortex; Neuroprotective Agents; Okadaic Acid; Organ Culture Techniques; Phosphorylation; Piperidines; Precipitin Tests; Rats; Rats, Sprague-Dawley; tau Proteins; Temporal Lobe; Thiazoles | 1998 |
Lubeluzole. JK 8792, R 87926, Prosynap.
Topics: Acute Disease; Brain Ischemia; Drugs, Investigational; Humans; Neuroprotective Agents; Piperidines; Stroke; Thiazoles | 1999 |
Transient up-regulation of gamma-aminobutyric acid(A) receptor binding by lubeluzole after neocortical specify lesion in rats.
Topics: Animals; Brain Ischemia; Male; Muscimol; Neocortex; Neuroprotective Agents; Photochemistry; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rose Bengal; Thiazoles; Tritium; Up-Regulation | 2000 |
Lubeluzole inhibits accumulation of extracellular glutamate in the hippocampus during transient global cerebral ischemia.
Topics: Action Potentials; Animals; Body Temperature; Brain Ischemia; Cardiovascular Physiological Phenomena; Extracellular Space; Glutamic Acid; Hippocampus; Microdialysis; Nerve Degeneration; Neurons; Neuroprotective Agents; Piperidines; Rabbits; Reperfusion Injury; Respiratory Physiological Phenomena; Thiazoles | 2001 |
Lubeluzole pretreatment does not provide neuroprotection against transient global cerebral ischemia in fetal sheep near term.
Topics: Acid-Base Equilibrium; Animals; Blood Gas Analysis; Brain; Brain Ischemia; Cerebrovascular Circulation; Female; Fetal Diseases; Gestational Age; Humans; Neuroprotective Agents; Piperidines; Pregnancy; Sheep; Thiazoles | 2002 |