Page last updated: 2024-09-05

lu 25-109 and Acute Confusional Senile Dementia

lu 25-109 has been researched along with Acute Confusional Senile Dementia in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (50.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cutler, NR; Forrest, M; Hourani, J; Jhee, SS; Mengel, H; Sramek, JJ	1
Langer, U; Moltzen-Lenz, S; Müller, D; Nitsch, RM; Wiegmann, H	1
Forrest, M; Loft, H; Mengel, H; Thal, LJ	1
Anderton, BH; Dayanandan, R; Forlenza, OV; Lovestone, S; Olesen, OF; Spink, JM	1

Trials

2 trial(s) available for lu 25-109 and Acute Confusional Senile Dementia

Article	Year
A bridging study of LU 25-109 in patients with probable Alzheimer's disease. Life sciences, 1998, Volume: 62, Issue:3 Topics: Aged; Alzheimer Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Placebos; Pyridines; Tetrazoles	1998
Lu 25-109, a muscarinic agonist, fails to improve cognition in Alzheimer's disease. Lu25-109 Study Group. Neurology, 2000, Jan-25, Volume: 54, Issue:2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cholinergic Fibers; Cognition; Double-Blind Method; Female; Genotype; Humans; Male; Middle Aged; Muscarinic Agonists; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazoles; Treatment Failure	2000

Article

Year

A bridging study of LU 25-109 in patients with probable Alzheimer's disease.

Life sciences, 1998, Volume: 62, Issue:3

Topics: Aged; Alzheimer Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Placebos; Pyridines; Tetrazoles

1998

Lu 25-109, a muscarinic agonist, fails to improve cognition in Alzheimer's disease. Lu25-109 Study Group.

Neurology, 2000, Jan-25, Volume: 54, Issue:2

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cholinergic Fibers; Cognition; Double-Blind Method; Female; Genotype; Humans; Male; Middle Aged; Muscarinic Agonists; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazoles; Treatment Failure

2000

Other Studies

2 other study(ies) available for lu 25-109 and Acute Confusional Senile Dementia

Article	Year
Lu 25-109, a combined m1 agonist and m2 antagonist, modulates regulated processing of the amyloid precursor protein of Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:8-9 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Hippocampus; Humans; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Protein Processing, Post-Translational; Pyridines; Rats; Rats, Inbred Lew; Tetrazoles; Transfection	1998
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:10 Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Lithium Chloride; Microtubules; Muscarinic Agonists; Neurons; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; tau Proteins; Tetrazoles; Thiadiazoles	2000

Article

Year

Lu 25-109, a combined m1 agonist and m2 antagonist, modulates regulated processing of the amyloid precursor protein of Alzheimer's disease.

Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:8-9

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Hippocampus; Humans; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Protein Processing, Post-Translational; Pyridines; Rats; Rats, Inbred Lew; Tetrazoles; Transfection

1998

Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons.

Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:10

Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Fetus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Lithium Chloride; Microtubules; Muscarinic Agonists; Neurons; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; tau Proteins; Tetrazoles; Thiadiazoles

2000