lu 135252 has been researched along with Hypertension, Pulmonary in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arzt, M; Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Wolf, K | 1 |
| Cernacek, P; Dupuis, J; Jasmin, JF | 1 |
| Shi, GY | 1 |
| Bartholdy, R; Boemke, W; Busch, T; Deja, M; Donaubauer, B; Francis, RC; Kaisers, U; Laudi, S; Petersen, B | 1 |
| Cernacek, P; Dupuis, J; Leung, TK; Prié, S; Ryan, JW | 1 |
| Dupuis, J; Prié, S; Stewart, DJ | 1 |
| Heller, A; Koch, T; Neuhof, H; Patt, B; Schmeck, J; van Ackern, K | 1 |
| Cernacek, P; Dupuis, J; Jasmin, JF; Lucas, M | 1 |
| Dupuis, J; Jasmin, JF; Lucas, M | 1 |
| Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Sandner, P; Wolf, K | 1 |
10 other study(ies) available for lu 135252 and Hypertension, Pulmonary
| Article | Year |
|---|---|
Effects of ET-A receptor blockade on eNOS gene expression in chronic hypoxic rat lungs.
Topics: Animals; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylpropionates; Pressure; Pulmonary Artery; Pulmonary Circulation; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Systole; Ventricular Function, Right | 2003 |
Activation of the right ventricular endothelin (ET) system in the monocrotaline model of pulmonary hypertension: response to chronic ETA receptor blockade.
Topics: Animals; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Endothelins; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Phenylpropionates; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A | 2003 |
[New choice of therapy of pulmonary hypertension: endothelin receptor antagonist].
Topics: Adult; Atrasentan; Bosentan; Endothelin Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Phenylpropionates; Pyrimidines; Pyrrolidines; Sulfonamides | 2005 |
Inhalation of the ETA receptor antagonist LU-135252 selectively attenuates hypoxic pulmonary vasoconstriction.
Topics: Administration, Inhalation; Animals; Blood Pressure; Disease Models, Animal; Endothelin A Receptor Antagonists; Hypertension, Pulmonary; Hypoxia; Phenylpropionates; Pulmonary Artery; Pulmonary Circulation; Pyrimidines; Receptor, Endothelin A; Swine; Vasoconstriction | 2008 |
The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphe nyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-treated ra
Topics: Administration, Oral; Animals; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptidyl-Dipeptidase A; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Ventricular Function, Right | 1997 |
EndothelinA receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension.
Topics: Animals; Endothelin Receptor Antagonists; Hypertension, Pulmonary; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Vasodilation | 1998 |
The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Embolism, Air; Endothelin Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Hypertension, Pulmonary; In Vitro Techniques; Oligopeptides; Perfusion; Phenylpropionates; Piperidines; Pulmonary Artery; Pulmonary Embolism; Pyrimidines; Rabbits; Radioimmunoassay; Thromboxane A2; Time Factors; Vascular Resistance | 1998 |
Effectiveness of a nonselective ET(A/B) and a selective ET(A) antagonist in rats with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Phenylpropionates; Pulmonary Circulation; Pyrimidines; Rats; Rats, Sprague-Dawley; Vascular Resistance | 2001 |
Effect of ET(A) receptor antagonist on pulmonary hypertension and vascular reactivity in rats with congestive heart failure.
Topics: Animals; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Myocardial Infarction; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptors, Endothelin; Vasoconstriction; Vasodilation | 2001 |
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Chronic Disease; Cytochrome P-450 Enzyme System; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Intramolecular Oxidoreductases; Male; Models, Animal; Molsidomine; Nitric Oxide Donors; Phenylpropionates; Pulmonary Artery; Pyrimidines; Random Allocation; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Systole; Ventricular Pressure | 2002 |