Page last updated: 2024-09-05

lu 135252 and Chronic Disease

lu 135252 has been researched along with Chronic Disease in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boujedaini, H; Henry, JP; Mulder, P; Münter, K; Renet, S; Richard, V; Thuillez, C	1
Arzt, M; Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Wolf, K	1
Dietz, R; Enseleit, F; Hürlimann, D; Lüscher, TF; Mitrovic, V; Noll, G; Notter, T; Pacher, R; Philipp, S; Rousson, V; Ruschitzka, F; Schulze, MR; Willenbrock, R	1
Piuhola, J; Ruskoaho, H; Szokodi, I	1
Blumberg, FC; Holmer, SR; Kammerl, M; Krämer, BK; Pfeifer, M; Riegger, GA; Schweda, A; Schweda, F	1
Blumberg, FC; Holmer, SR; Krämer, BK; Nabel, C; Pfeifer, M; Riegger, GA; Schweda, A; Schweda, F	1
Bauersachs, J; Braun, C; Ertl, G; Fraccarollo, D; Kirchengast, M; Rohmeiss, P; Schilling, L; Widder, J	1
Berger, R; Frey, B; Heher, S; Hülsmann, M; Neunteufl, T; Pacher, R; Stanek, B	1
Cheng, TO	1
Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Sandner, P; Wolf, K	1

Trials

2 trial(s) available for lu 135252 and Chronic Disease

Article	Year
Hemodynamic and neurohumoral effects of selective endothelin A (ET(A)) receptor blockade in chronic heart failure: the Heart Failure ET(A) Receptor Blockade Trial (HEAT). Circulation, 2002, Nov-19, Volume: 106, Issue:21 Topics: Blood Pressure; Catecholamines; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Endothelin Receptor Antagonists; Europe; Female; Follow-Up Studies; Headache; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Hypotension; Male; Middle Aged; Phenylpropionates; Pulmonary Wedge Pressure; Pyrimidines; Receptor, Endothelin A; Shock, Cardiogenic; Treatment Outcome; Vascular Resistance; Ventricular Fibrillation	2002
Effects of endothelin a receptor blockade on endothelial function in patients with chronic heart failure. Circulation, 2001, Feb-20, Volume: 103, Issue:7 Topics: Blood Flow Velocity; Brachial Artery; Chronic Disease; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Endothelium, Vascular; Female; Heart Failure; Heart Function Tests; Humans; Linear Models; Male; Middle Aged; Nitroglycerin; Phenylpropionates; Protein Precursors; Pyrimidines; Receptor, Endothelin A; Treatment Outcome; Vasodilation	2001

Article

Year

Hemodynamic and neurohumoral effects of selective endothelin A (ET(A)) receptor blockade in chronic heart failure: the Heart Failure ET(A) Receptor Blockade Trial (HEAT).

Circulation, 2002, Nov-19, Volume: 106, Issue:21

Topics: Blood Pressure; Catecholamines; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Endothelin Receptor Antagonists; Europe; Female; Follow-Up Studies; Headache; Heart Failure; Heart Function Tests; Hemodynamics; Humans; Hypotension; Male; Middle Aged; Phenylpropionates; Pulmonary Wedge Pressure; Pyrimidines; Receptor, Endothelin A; Shock, Cardiogenic; Treatment Outcome; Vascular Resistance; Ventricular Fibrillation

2002

Effects of endothelin a receptor blockade on endothelial function in patients with chronic heart failure.

Circulation, 2001, Feb-20, Volume: 103, Issue:7

Topics: Blood Flow Velocity; Brachial Artery; Chronic Disease; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Endothelium, Vascular; Female; Heart Failure; Heart Function Tests; Humans; Linear Models; Male; Middle Aged; Nitroglycerin; Phenylpropionates; Protein Precursors; Pyrimidines; Receptor, Endothelin A; Treatment Outcome; Vasodilation

2001

Other Studies

8 other study(ies) available for lu 135252 and Chronic Disease

Article	Year
Long-term survival and hemodynamics after endothelin-a receptor antagonism and angiotensin-converting enzyme inhibition in rats with chronic heart failure: monotherapy versus combination therapy. Circulation, 2002, Aug-27, Volume: 106, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Chronic Disease; Coronary Vessels; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Endothelin Receptor Antagonists; Heart Failure; Hemodynamics; Ligation; Male; Myocardium; Peptidyl-Dipeptidase A; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Stroke Volume; Survival Rate; Ventricular Function, Left; Ventricular Remodeling; Wakefulness	2002
Effects of ET-A receptor blockade on eNOS gene expression in chronic hypoxic rat lungs. Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:2 Topics: Animals; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylpropionates; Pressure; Pulmonary Artery; Pulmonary Circulation; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Systole; Ventricular Function, Right	2003
Endothelin receptor blockade and exacerbation of heart failure. Circulation, 2003, Jun-10, Volume: 107, Issue:22 Topics: Animals; Bosentan; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelins; Heart; Heart Failure; Humans; Myocardial Contraction; Phenylpropionates; Pyrimidines; Rats; Receptor, Endothelin A; Sulfonamides; Vascular Resistance; Water-Electrolyte Balance	2003
Effects of chronic hypoxia on renal renin gene expression in rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1 Topics: Animals; Blood Pressure; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Gene Expression; Hypoxia; Kidney; Male; Molsidomine; Nitric Oxide Donors; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Renin; RNA, Messenger	2000
Effects of chronic hypoxia on renal PDGF-A, PDGF-B, and VEGF gene expression in rats. Nephron, 2000, Volume: 86, Issue:2 Topics: Animals; Chronic Disease; Endothelial Growth Factors; Endothelin Receptor Antagonists; Gene Expression Regulation; Hematocrit; Hemodynamics; Hypoxia; Kidney; Lymphokines; Male; Molsidomine; Nitric Oxide Donors; Phenylpropionates; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Improvement of renal dysfunction in rats with chronic heart failure after myocardial infarction by treatment with the endothelin A receptor antagonist, LU 135252. Journal of hypertension, 2000, Volume: 18, Issue:10 Topics: Animals; Chronic Disease; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Kidney; Male; Myocardial Infarction; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Renal Artery; Vasodilation	2000
Endothelin receptor blockade in congestive heart failure. Circulation, 2001, Oct-30, Volume: 104, Issue:18 Topics: Acute Disease; Antihypertensive Agents; Bosentan; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelin-1; Exercise Tolerance; Heart Failure; Hemodynamics; Humans; Phenylpropionates; Pyridines; Pyrimidines; Sulfonamides; Tetrazoles; Treatment Outcome; Vasodilator Agents	2001
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension. Cardiovascular research, 2002, Volume: 55, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Chronic Disease; Cytochrome P-450 Enzyme System; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Intramolecular Oxidoreductases; Male; Models, Animal; Molsidomine; Nitric Oxide Donors; Phenylpropionates; Pulmonary Artery; Pyrimidines; Random Allocation; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Systole; Ventricular Pressure	2002