lu 135252 has been researched along with Cardiovascular Stroke in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 11 (84.62) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulhak, A; Gourine, AV; Molosh, AI; Pernow, J; Poputnikov, D; Sjöquist, PO | 1 |
| Gonon, AT; Pernow, J; Shimizu, M; Wang, QD | 1 |
| Calderoni, A; Cernacek, P; Nguyen, QT; Picard, P; Rouleau, JL; Sirois, P; Stewart, DJ; White, M | 1 |
| Bauersachs, J; Ertl, G; Fraccarollo, D; Galuppo, P; Widder, J | 1 |
| Cernacek, P; Dupuis, J; Lucas, M; Thorin, E | 1 |
| Calderone, A; Colombo, F; Dupuis, J; Nguyen, QT; Rouleau, JL | 1 |
| Bauersachs, J; Braun, C; Ertl, G; Fraccarollo, D; Kirchengast, M; Rohmeiss, P; Schilling, L; Widder, J | 1 |
| del Balzo, U; DeMaria, AN; Flaim, SF; Galiuto, L; Iliceto, S; Kirchengast, M; May-Newman, K; Wolf, PL | 1 |
| Gonon, AT; Gourine, AV; Pernow, J | 1 |
| Dupuis, J; Jasmin, JF; Lucas, M | 1 |
| Alving, K; Gonon, AT; Gourine, AV; Middelveld, RJ; Pernow, J | 1 |
| Bauersachs, J; Ertl, G; Fraccarollo, D; Galuppo, P | 1 |
| Angelini, A; Basso, C; Della Barbera, M; Iliceto, S; Kirchengast, M; Thiene, G | 1 |
13 other study(ies) available for lu 135252 and Cardiovascular Stroke
| Article | Year |
|---|---|
Endothelin-1 exerts a preconditioning-like cardioprotective effect against ischaemia/reperfusion injury via the ET(A) receptor and the mitochondrial K(ATP) channel in the rat in vivo.
Topics: Animals; Electrocardiography; Endothelin-1; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Phenylpropionates; Potassium Channels; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Reperfusion Injury | 2005 |
The novel non-peptide selective endothelin A receptor antagonist LU 135,252 protects against myocardial ischaemic and reperfusion injury in the pig.
Topics: Animals; Coronary Circulation; Coronary Vessels; Endothelin Receptor Antagonists; Endothelins; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Pyrimidines; Receptor, Endothelin A; Swine | 1998 |
Endothelin A receptor blockade causes adverse left ventricular remodeling but improves pulmonary artery pressure after infarction in the rat.
Topics: Animals; Blood Pressure; Endothelin Receptor Antagonists; Intubation, Gastrointestinal; Isomerism; Male; Myocardial Infarction; Phenylpropionates; Pulmonary Artery; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Ventricular Remodeling | 1998 |
Endothelin-receptor blockade improves endothelial vasomotor dysfunction in heart failure.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Male; Myocardial Infarction; Nitroprusside; Oxygen; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Renin; Sulfonamides; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Role of ET(A) receptors in the regulation of vascular reactivity in rats with congestive heart failure.
Topics: Animals; Cerebral Arteries; Electrocardiography; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Heart Failure; Hemodynamics; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Infarction; Nitroarginine; Nitroprusside; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Vasoconstrictor Agents; Vasodilation; Viper Venoms | 2000 |
LU135252, an endothelin(A) receptor antagonist did not prevent pulmonary vascular remodelling or lung fibrosis in a rat model of myocardial infarction.
Topics: Animals; Disease Models, Animal; Endothelin Receptor Antagonists; Hemodynamics; Male; Myocardial Infarction; Phenotype; Phenylpropionates; Pulmonary Artery; Pulmonary Fibrosis; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A | 2000 |
Improvement of renal dysfunction in rats with chronic heart failure after myocardial infarction by treatment with the endothelin A receptor antagonist, LU 135252.
Topics: Animals; Chronic Disease; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Kidney; Male; Myocardial Infarction; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Renal Artery; Vasodilation | 2000 |
Ischemia-reperfusion injury at the microvascular level: treatment by endothelin A-selective antagonist and evaluation by myocardial contrast echocardiography.
Topics: Animals; Coronary Circulation; Dogs; Endothelin Receptor Antagonists; Hemodynamics; Microcirculation; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Phenylpropionates; Pyrimidines; Receptor, Endothelin A; Ultrasonography | 2000 |
Involvement of nitric oxide in cardioprotective effect of endothelin receptor antagonist during ischemia-reperfusion.
Topics: Animals; Blood Pressure; Coronary Circulation; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylpropionates; Pyrimidines; Receptor, Endothelin A; Survival Rate; Swine | 2001 |
Effect of ET(A) receptor antagonist on pulmonary hypertension and vascular reactivity in rats with congestive heart failure.
Topics: Animals; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Myocardial Infarction; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptors, Endothelin; Vasoconstriction; Vasodilation | 2001 |
Limitation of infarct size and attenuation of myeloperoxidase activity by an endothelin A receptor antagonist following ischaemia and reperfusion.
Topics: Animals; Antibodies; Blood Pressure; Cardiotonic Agents; Endothelin Receptor Antagonists; Female; Immunohistochemistry; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Neutrophils; Peroxidase; Phenylpropionates; Pulmonary Wedge Pressure; Pyrimidines; Receptor, Endothelin A; Receptors, Endothelin; Swine | 2001 |
Collagen accumulation after myocardial infarction: effects of ETA receptor blockade and implications for early remodeling.
Topics: Animals; Blotting, Western; Collagen; Collagen Type I; Collagen Type III; Collagenases; Endothelin Receptor Antagonists; Female; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Models, Animal; Myocardial Infarction; Myocardium; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling | 2002 |
Endothelin A-receptor antagonist administration immediately after experimental myocardial infarction with reperfusion does not affect scar healing in dogs.
Topics: Administration, Oral; Analysis of Variance; Animals; Dogs; Endothelin Receptor Antagonists; Fibrosis; Image Processing, Computer-Assisted; Immunohistochemistry; Injections, Intravenous; Male; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Pyrimidines; Receptor, Endothelin A; Transforming Growth Factor beta | 2002 |