loxoprofen has been researched along with Prostatic Hyperplasia in 2 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We explored the effectiveness of loxoprofen sodium (loxoprofen), which is the most common non-steroidal anti-inflammatory drug (NSAID) in Japan, for patients with benign prostatic hyperplasia (BPH) complaining of nocturia." | 9.11 | Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping. ( Araki, T; Kumon, H; Yokoyama, T, 2004) |
| "We explored the effectiveness of loxoprofen sodium (loxoprofen), which is the most common non-steroidal anti-inflammatory drug (NSAID) in Japan, for patients with benign prostatic hyperplasia (BPH) complaining of nocturia." | 5.11 | Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping. ( Araki, T; Kumon, H; Yokoyama, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araki, T | 1 |
| Yokoyama, T | 1 |
| Kumon, H | 1 |
| Saito, M | 1 |
| Kawatani, M | 1 |
| Kinoshita, Y | 1 |
| Satoh, K | 1 |
| Miyagawa, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Clinical Efficacy of Non-steroidal Anti-inflammation Drugs in Patients With Benign Prostatic Hyperplasia: A Prospective Randomized Multicenter Trial[NCT00687388] | Phase 4 | 0 participants (Actual) | Interventional | 2008-05-31 | Withdrawn (stopped due to in order to prepare a new clinical trial to evaluate with pathological change) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for loxoprofen and Prostatic Hyperplasia
| Article | Year |
|---|---|
Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Humans; Male; Middle Aged; Phenylp | 2004 |
Effectiveness of an anti-inflammatory drug, loxoprofen, for patients with nocturia.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Male; Middle Aged; Patient Satisfacti | 2005 |