Page last updated: 2024-10-30

loxoprofen and Pain, Postoperative

loxoprofen has been researched along with Pain, Postoperative in 13 studies

loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"75% ropivacaine is safe and effective, and provides adequate analgesia for a long period in adult patients following an inguinal hernia repair procedure."9.16[Local instillation of 0.75% ropivacaine compared with intravenous fentanyl and flurbiprofen for postoperative analgesia following inguinal hernia repair in adults]. ( Kato, T; Kinoshita, H; Miyoshi, H; Tanaka, H, 2012)
"Celecoxib is a selective COX-2 inhibitor and has a lower effect of platelet aggregation compared with conventional non-steroidal anti-inflammatory drugs (NSAIDs)."5.43A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy. ( Ariki, M; Fukushima, N; Hirai, T; Miyahara, N; Yoshiga, A, 2016)
"A new perioperative management method was explored by assessing the safety and the efficacy of pregabalin for the treatment of intercostal neuralgia after thoracotomy."5.20Pregabalin reduces post-surgical pain after thoracotomy: a prospective, randomized, controlled trial. ( Dejima, H; Kawamura, M; Matsutani, N; Takahashi, Y, 2015)
"75% ropivacaine is safe and effective, and provides adequate analgesia for a long period in adult patients following an inguinal hernia repair procedure."5.16[Local instillation of 0.75% ropivacaine compared with intravenous fentanyl and flurbiprofen for postoperative analgesia following inguinal hernia repair in adults]. ( Kato, T; Kinoshita, H; Miyoshi, H; Tanaka, H, 2012)
"Celecoxib was discontinued in one patient on day 2 at the patient's request."2.80Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study. ( Imura, T; Inoue, G; Miyagi, M; Nakazawa, T; Saito, W; Sekiguchi, H; Takahira, N; Takaso, M; Uchida, K, 2015)
"Postoperative pain was evaluated at the clinic on the 1st, 7th and 14th postoperative day (POD) using a visual analogue scale (VAS), as was the number of loxoprofen tablets consumed, and the results were compared among the 3 groups with statistical significance of P<0."2.72Premedication with cyclooxygenase-2 inhibitor meloxicam reduced postoperative pain in patients after oral surgery. ( Aoki, T; Izawa, K; Kaneko, A; Naito, H; Ota, Y; Sakamoto, H; Shiiki, K; Yamaguchi, H, 2006)
"We analyzed postoperative pain intensity, the incidence rate of acute kidney injury, drug-induced liver injury, and rate of elevation in serum creatinine after open radical prostatectomy."1.62Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis. ( Hamada, S; Hamada, Y; Hara, K; Kadowaki, D; Miyamura, S; Nishimura, F; Nojima, M; Oniki, K; Saruwatari, J; Ushijima, T, 2021)
"There were questionnaires about postoperative pain for patients whose mandibular impacted third teeth were extracted from July 2017 to August 2017 in First Clinical Division of Peking University School and Hospital of Stomatology."1.48[Preemptive analgesia with loxoprofen sodiumorally in extraction of impacted teeth]. ( Chen, Q; Chen, YH; Gao, W; Li, JQ; Liu, WS; Meng, T; Zhang, X; Zhang, ZY, 2018)
"Celecoxib is a selective COX-2 inhibitor and has a lower effect of platelet aggregation compared with conventional non-steroidal anti-inflammatory drugs (NSAIDs)."1.43A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy. ( Ariki, M; Fukushima, N; Hirai, T; Miyahara, N; Yoshiga, A, 2016)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's9 (69.23)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Nishimura, F1
Ushijima, T1
Nojima, M1
Hamada, S1
Hara, K1
Hamada, Y1
Kadowaki, D1
Miyamura, S1
Oniki, K1
Saruwatari, J1
Meng, T1
Zhang, ZY1
Zhang, X1
Chen, YH1
Li, JQ1
Chen, Q1
Liu, WS1
Gao, W1
Hirai, T1
Fukushima, N1
Miyahara, N1
Yoshiga, A1
Ariki, M1
Kanazawa, H1
Kotoda, A1
Akimoto, T1
Shinozaki, T1
Inoue, M1
Sugimoto, H1
Kusano, E1
Wada, T1
Yamauchi, M1
Oki, G1
Sonoda, T1
Yamakage, M1
Yamashita, T1
Yamashita, Y1
Sano, N1
Shimohira, D1
Danjo, A1
Goto, M1
Matsutani, N1
Dejima, H1
Takahashi, Y1
Kawamura, M1
Sekiguchi, H1
Inoue, G1
Nakazawa, T1
Imura, T1
Saito, W1
Uchida, K1
Miyagi, M1
Takahira, N1
Takaso, M1
Onda, A1
Ogoshi, A1
Itoh, M1
Nakagawa, T1
Kimura, M1
Miyoshi, H1
Tanaka, H1
Kato, T1
Kinoshita, H1
Ise, Y1
Murota, Y1
Takayama, K1
Narita, M1
Suzuki, T1
Soh, S1
Katayama, S1
Hirano, M1
Fujita, K1
Sakamoto, O1
Matsumoto, M1
Kohrogi, H1
Suga, M1
Aoki, T1
Yamaguchi, H1
Naito, H1
Shiiki, K1
Izawa, K1
Ota, Y1
Sakamoto, H1
Kaneko, A1

Trials

7 trials available for loxoprofen and Pain, Postoperative

ArticleYear
Efficacy of axillary nerve block in elbow arthroscopic surgery: a randomized trial.
    Journal of shoulder and elbow surgery, 2014, Volume: 23, Issue:3

    Topics: Analgesics; Anesthetics, Local; Arthroscopy; Axilla; Elbow; Female; Humans; Male; Middle Aged; Nerve

2014
A parallel-group comparison study of celecoxib with loxoprofen sodium in third mandibular molar extraction patients.
    International journal of oral and maxillofacial surgery, 2014, Volume: 43, Issue:12

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Female

2014
Pregabalin reduces post-surgical pain after thoracotomy: a prospective, randomized, controlled trial.
    Surgery today, 2015, Volume: 45, Issue:11

    Topics: Administration, Oral; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Female; Huma

2015
Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2015, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relat

2015
Comparison of the effects of treatment with celecoxib, loxoprofen, and acetaminophen on postoperative acute pain after arthroscopic knee surgery: A randomized, parallel-group trial.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2016, Volume: 21, Issue:2

    Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Anterior Cruciate Ligament Injuries; Ant

2016
[Local instillation of 0.75% ropivacaine compared with intravenous fentanyl and flurbiprofen for postoperative analgesia following inguinal hernia repair in adults].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:10

    Topics: Aged; Aged, 80 and over; Amides; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Anti-Infl

2012
Premedication with cyclooxygenase-2 inhibitor meloxicam reduced postoperative pain in patients after oral surgery.
    International journal of oral and maxillofacial surgery, 2006, Volume: 35, Issue:7

    Topics: Administration, Oral; Adult; Analysis of Variance; Anesthesia, Local; Anti-Inflammatory Agents, Non-

2006

Other Studies

6 other studies available for loxoprofen and Pain, Postoperative

ArticleYear
Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:10

    Topics: Acetaminophen; Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug

2021
[Preemptive analgesia with loxoprofen sodiumorally in extraction of impacted teeth].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2018, Feb-18, Volume: 50, Issue:1

    Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain, Postoperative; Phenylpropionates;

2018
A Comparison of Analgesic Effect between Loxoprofen and Celecoxib and the Frequency of the Hemorrhage Following Tonsillectomy.
    Nihon Jibiinkoka Gakkai kaiho, 2016, Volume: 119, Issue:8

    Topics: Adult; Analgesics; Celecoxib; Female; Hemorrhage; Humans; Male; Pain, Postoperative; Phenylpropionat

2016
Serial Tc-99m MAG3 renography evaluating the recovery of acute kidney injury associated with minimal change nephrotic syndrome.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:9

    Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Susceptibility; Fracture

2013
[The analysis of prescription frequency and the factors on adverse reactions of NSAIDs for post-operative pain in orthopedic patients].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2003, Volume: 123, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cost Savings; Drug Prescriptions; Female; Heal

2003
[A case of loxoprofen sodium-induced bronchiolitis obliterans organizing pneumonia (BOOP)].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2003, Volume: 41, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cryptogenic Organizing Pneumonia; Humans; Lung Neopla

2003