loxoprofen has been researched along with Hematochezia in 6 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Hematochezia: The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amagase, K | 3 |
| Yoshida, Y | 1 |
| Hara, D | 1 |
| Murakami, T | 1 |
| Takeuchi, K | 3 |
| Izumi, N | 1 |
| Takahira, Y | 1 |
| Wada, T | 1 |
| Nakamura, E | 1 |
| Kato, S | 1 |
| Yamakawa, N | 1 |
| Suemasu, S | 1 |
| Matoyama, M | 1 |
| Kimoto, A | 1 |
| Takeda, M | 1 |
| Tanaka, K | 1 |
| Ishihara, T | 1 |
| Katsu, T | 1 |
| Okamoto, Y | 1 |
| Otsuka, M | 1 |
| Mizushima, T | 1 |
| Nagai, N | 1 |
| Takeda, A | 1 |
| Itanami, Y | 1 |
| Ito, Y | 1 |
| Nakase, H | 1 |
| Itani, T | 1 |
| Mimura, J | 1 |
| Kawasaki, T | 1 |
| Komori, H | 1 |
| Hashimoto, K | 1 |
| Chiba, T | 1 |
1 review available for loxoprofen and Hematochezia
| Article | Year |
|---|---|
[Glutamate as a potential protective drug in the gastrointestinal mucosa].
Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Gastr | 2015 |
5 other studies available for loxoprofen and Hematochezia
| Article | Year |
|---|---|
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage; | 2013 |
Importance of cyclooxygenase-1/prostacyclin in modulating gastric mucosal integrity under stress conditions.
Topics: Animals; Cold Temperature; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; | 2014 |
Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; | 2010 |
Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Experimental; Drug T | 2012 |
Colonic ulceration caused by administration of loxoprofen sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis, Ulcerative; Colonoscopy; | 1999 |