loxoprofen has been researched along with Diabetes Mellitus, Type 2 in 1 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because oral nonsteroidal anti-inflammatory drugs (NSAIDs) have adverse effects on kidney function, patients with kidney diseases are administered these drugs as transdermal patches." | 2.79 | Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy. ( Araki, H; Araki, S; Isshiki, K; Kashiwagi, A; Kume, S; Kuwagata, S; Maegawa, H; Morita, Y; Soumura, M; Uzu, T; Yamahara, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araki, H | 1 |
| Kuwagata, S | 1 |
| Soumura, M | 1 |
| Yamahara, K | 1 |
| Morita, Y | 1 |
| Kume, S | 1 |
| Isshiki, K | 1 |
| Araki, S | 1 |
| Kashiwagi, A | 1 |
| Maegawa, H | 1 |
| Uzu, T | 1 |
1 trial available for loxoprofen and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; | 2014 |