loxoprofen has been researched along with Demyelinating Diseases in 1 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The disease appeared during low-dose oral methotrexate (MTX) therapy for rheumatoid arthritis." | 7.74 | Massive myelinolytic leukoencephalopathy in a patient medicated with low-dose oral methotrexate for rheumatoid arthritis: an autopsy report. ( Harigaya, Y; Igeta, Y; Itoh, H; Nakazato, Y; Sasaki, N; Yokoo, H, 2007) |
| " The disease appeared during low-dose oral methotrexate (MTX) therapy for rheumatoid arthritis." | 3.74 | Massive myelinolytic leukoencephalopathy in a patient medicated with low-dose oral methotrexate for rheumatoid arthritis: an autopsy report. ( Harigaya, Y; Igeta, Y; Itoh, H; Nakazato, Y; Sasaki, N; Yokoo, H, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokoo, H | 1 |
| Nakazato, Y | 1 |
| Harigaya, Y | 1 |
| Sasaki, N | 1 |
| Igeta, Y | 1 |
| Itoh, H | 1 |
1 other study available for loxoprofen and Demyelinating Diseases
| Article | Year |
|---|---|
Massive myelinolytic leukoencephalopathy in a patient medicated with low-dose oral methotrexate for rheumatoid arthritis: an autopsy report.
Topics: Adenocarcinoma; Administration, Oral; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non- | 2007 |