loxoprofen has been researched along with Chronic Pain in 4 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding." | 8.02 | Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021) |
| "In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)." | 7.30 | Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023) |
| "The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back pain (LBP), using real-world cost information for loxoprofen and pharmacotherapy for gastrointestinal bleeding." | 4.02 | Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan. ( Kamae, I; Karasawa, Y; Murata, T; Nozawa, K; Sakamoto, C; Soen, S; Zeniya, S, 2021) |
| "In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality of life (QOL)." | 3.30 | Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee. ( Aono, H; Endo, M; Hara, T; Kawahara, S; Kawano, T; Mawatari, T; Miyaji, T; Miyake, M; Nakashima, Y; Sakamoto, S; Sato, T; Shimokawa, M; Takano, T; Tokunaga, M; Zenda, S, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endo, M | 1 |
| Kawahara, S | 1 |
| Sato, T | 1 |
| Tokunaga, M | 1 |
| Hara, T | 1 |
| Mawatari, T | 1 |
| Kawano, T | 1 |
| Zenda, S | 1 |
| Miyaji, T | 1 |
| Shimokawa, M | 1 |
| Sakamoto, S | 1 |
| Takano, T | 1 |
| Miyake, M | 1 |
| Aono, H | 1 |
| Nakashima, Y | 1 |
| Lee, B | 1 |
| Seo, BK | 2 |
| Kwon, OJ | 1 |
| Jo, DJ | 2 |
| Lee, JH | 2 |
| Lee, S | 2 |
| Karasawa, Y | 1 |
| Kamae, I | 1 |
| Nozawa, K | 1 |
| Zeniya, S | 1 |
| Murata, T | 1 |
| Soen, S | 1 |
| Sakamoto, C | 1 |
| Kim, PK | 1 |
| Baek, YH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Research on the Efficacy and Safety of East-West Collaborative Treatment Using NSAIDs and BV on Chronic Cervical Pain; A Randomized, Controlled, Parallel, Pilot Study[NCT01922466] | Phase 2 | 60 participants (Anticipated) | Interventional | 2013-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for loxoprofen and Chronic Pain
| Article | Year |
|---|---|
Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee.
Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal | 2023 |
Effect of Combined Bee Venom Acupuncture and NSAID Treatment for Non-Specific Chronic Neck Pain: A Randomized, Assessor-Blinded, Pilot Clinical Trial.
Topics: Acupuncture Therapy; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bee Venoms; Chronic Pain; Combi | 2021 |
Bee venom acupuncture, NSAIDs or combined treatment for chronic neck pain: study protocol for a randomized, assessor-blind trial.
Topics: Acupuncture Therapy; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-St | 2014 |
1 other study available for loxoprofen and Chronic Pain
| Article | Year |
|---|---|
Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan.
Topics: Aged; Aged, 80 and over; Celecoxib; Chronic Pain; Computer Simulation; Cost Savings; Cost-Benefit An | 2021 |